FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0438, 869 aa 1>>>pF1KB0438 869 - 869 aa - 869 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2087+/-0.000341; mu= 3.4125+/- 0.021 mean_var=216.2591+/-43.903, 0's: 0 Z-trim(122.0): 18 B-trim: 356 in 1/58 Lambda= 0.087214 statistics sampled from 39447 (39465) to 39447 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.463), width: 16 Scan time: 16.000 The best scores are: opt bits E(85289) NP_005670 (OMIM: 604905) TATA box-binding protein- ( 869) 6076 777.7 0 XP_005256283 (OMIM: 604905) PREDICTED: TATA box-bi ( 869) 6065 776.3 0 XP_006721388 (OMIM: 604905) PREDICTED: TATA box-bi ( 870) 6065 776.3 0 XP_005256284 (OMIM: 604905) PREDICTED: TATA box-bi ( 802) 5591 716.7 1.1e-205 XP_016879335 (OMIM: 604905) PREDICTED: TATA box-bi ( 802) 5591 716.7 1.1e-205 XP_016879336 (OMIM: 604905) PREDICTED: TATA box-bi ( 776) 3937 508.5 4.7e-143 XP_016879334 (OMIM: 604905) PREDICTED: TATA box-bi ( 843) 3937 508.6 5.1e-143 NP_001230085 (OMIM: 604905) TATA box-binding prote ( 843) 3937 508.6 5.1e-143 XP_006721389 (OMIM: 604905) PREDICTED: TATA box-bi ( 844) 3937 508.6 5.1e-143 NP_647610 (OMIM: 604905) TATA box-binding protein- ( 775) 3917 506.0 2.7e-142 XP_016879337 (OMIM: 604905) PREDICTED: TATA box-bi ( 537) 3747 484.5 5.5e-136 NP_001230087 (OMIM: 604905) TATA box-binding prote ( 537) 3747 484.5 5.5e-136 NP_001230086 (OMIM: 604905) TATA box-binding prote ( 537) 3747 484.5 5.5e-136 NP_001230088 (OMIM: 604905) TATA box-binding prote ( 460) 3210 416.9 1.1e-115 NP_001230089 (OMIM: 604905) TATA box-binding prote ( 392) 2721 355.3 3.1e-97 >>NP_005670 (OMIM: 604905) TATA box-binding protein-asso (869 aa) initn: 6076 init1: 6076 opt: 6076 Z-score: 4143.0 bits: 777.7 E(85289): 0 Smith-Waterman score: 6076; 100.0% identity (100.0% similar) in 869 aa overlap (1-869:1-869) 10 20 30 40 50 60 pF1KB0 MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 ATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRPRVVLDVTEQISRFLLDHGDVAFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRPRVVLDVTEQISRFLLDHGDVAFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 PLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 HFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPGP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 FHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKW 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 NHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 DSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 RQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSER 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 PPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA 790 800 810 820 830 840 850 860 pF1KB0 SSVRATRSQQHTPVLSSSQPLRKKPRMGF ::::::::::::::::::::::::::::: NP_005 SSVRATRSQQHTPVLSSSQPLRKKPRMGF 850 860 >>XP_005256283 (OMIM: 604905) PREDICTED: TATA box-bindin (869 aa) initn: 6065 init1: 6065 opt: 6065 Z-score: 4135.5 bits: 776.3 E(85289): 0 Smith-Waterman score: 6065; 99.9% identity (99.9% similar) in 869 aa overlap (1-869:1-869) 10 20 30 40 50 60 pF1KB0 MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 ATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRPRVVLDVTEQISRFLLDHGDVAFA :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: XP_005 ATPGPLPMLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 PLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 HFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPGP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 FHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 VCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKW 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 NHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 DSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 PQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 RQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSER 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 LGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 PPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA 790 800 810 820 830 840 850 860 pF1KB0 SSVRATRSQQHTPVLSSSQPLRKKPRMGF ::::::::::::::::::::::::::::: XP_005 SSVRATRSQQHTPVLSSSQPLRKKPRMGF 850 860 >>XP_006721388 (OMIM: 604905) PREDICTED: TATA box-bindin (870 aa) initn: 6065 init1: 6065 opt: 6065 Z-score: 4135.5 bits: 776.3 E(85289): 0 Smith-Waterman score: 6065; 99.9% identity (99.9% similar) in 869 aa overlap (1-869:2-870) 10 20 30 40 50 pF1KB0 MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MMDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 PATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRPRVVLDVTEQISRFLLDHGDVAF ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_006 PATPGPLPMLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 APLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 PILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 LHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 PFHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PFHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB0 AVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGC 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB0 GLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLK 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB0 WNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSR 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB0 IDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQL 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB0 RPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFT 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB0 HRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSE 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB0 RLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPE 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB0 WPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQ 790 800 810 820 830 840 840 850 860 pF1KB0 ASSVRATRSQQHTPVLSSSQPLRKKPRMGF :::::::::::::::::::::::::::::: XP_006 ASSVRATRSQQHTPVLSSSQPLRKKPRMGF 850 860 870 >>XP_005256284 (OMIM: 604905) PREDICTED: TATA box-bindin (802 aa) initn: 5591 init1: 5591 opt: 5591 Z-score: 3813.7 bits: 716.7 E(85289): 1.1e-205 Smith-Waterman score: 5591; 99.9% identity (99.9% similar) in 802 aa overlap (68-869:1-802) 40 50 60 70 80 90 pF1KB0 PEAQPQNSENGALHVTKDLLWEPATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRP ::::::::::::::::::::::: :::::: XP_005 MLPPLIDPWDPGLTARDLLFRGGCRYRKRP 10 20 30 100 110 120 130 140 150 pF1KB0 RVVLDVTEQISRFLLDHGDVAFAPLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RVVLDVTEQISRFLLDHGDVAFAPLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGH 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB0 QPWGCPWAYLSNRQRRFSILGGPILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPWGCPWAYLSNRQRRFSILGGPILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALA 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB0 WVPGRTPQFGQLVYPAGGAQDRLHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WVPGRTPQFGQLVYPAGGAQDRLHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQ 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB0 GESKALIYTFLPHWLTCYLTPGPFHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GESKALIYTFLPHWLTCYLTPGPFHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEK 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB0 GATGISLSPHLPGELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GATGISLSPHLPGELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHP 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB0 RVLTVGDRTGVKMLDTQGPPGCGLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RVLTVGDRTGVKMLDTQGPPGCGLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLH 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB0 LVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLL 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB0 HLAGEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLAGEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPS 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB0 APTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCS 520 530 540 550 560 570 640 650 660 670 680 690 pF1KB0 QWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDL 580 590 600 610 620 630 700 710 720 730 740 750 pF1KB0 GSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLS 640 650 660 670 680 690 760 770 780 790 800 810 pF1KB0 SSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRD 700 710 720 730 740 750 820 830 840 850 860 pF1KB0 YMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF 760 770 780 790 800 >>XP_016879335 (OMIM: 604905) PREDICTED: TATA box-bindin (802 aa) initn: 5591 init1: 5591 opt: 5591 Z-score: 3813.7 bits: 716.7 E(85289): 1.1e-205 Smith-Waterman score: 5591; 99.9% identity (99.9% similar) in 802 aa overlap (68-869:1-802) 40 50 60 70 80 90 pF1KB0 PEAQPQNSENGALHVTKDLLWEPATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRP ::::::::::::::::::::::: :::::: XP_016 MLPPLIDPWDPGLTARDLLFRGGCRYRKRP 10 20 30 100 110 120 130 140 150 pF1KB0 RVVLDVTEQISRFLLDHGDVAFAPLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVVLDVTEQISRFLLDHGDVAFAPLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGH 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB0 QPWGCPWAYLSNRQRRFSILGGPILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPWGCPWAYLSNRQRRFSILGGPILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALA 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB0 WVPGRTPQFGQLVYPAGGAQDRLHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WVPGRTPQFGQLVYPAGGAQDRLHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQ 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB0 GESKALIYTFLPHWLTCYLTPGPFHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GESKALIYTFLPHWLTCYLTPGPFHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEK 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB0 GATGISLSPHLPGELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GATGISLSPHLPGELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHP 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB0 RVLTVGDRTGVKMLDTQGPPGCGLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVLTVGDRTGVKMLDTQGPPGCGLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLH 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB0 LVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLL 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB0 HLAGEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLAGEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPS 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB0 APTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCS 520 530 540 550 560 570 640 650 660 670 680 690 pF1KB0 QWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDL 580 590 600 610 620 630 700 710 720 730 740 750 pF1KB0 GSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLS 640 650 660 670 680 690 760 770 780 790 800 810 pF1KB0 SSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRD 700 710 720 730 740 750 820 830 840 850 860 pF1KB0 YMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF 760 770 780 790 800 >>XP_016879336 (OMIM: 604905) PREDICTED: TATA box-bindin (776 aa) initn: 5380 init1: 3937 opt: 3937 Z-score: 2689.2 bits: 508.5 E(85289): 4.7e-143 Smith-Waterman score: 5332; 96.5% identity (96.6% similar) in 802 aa overlap (68-869:1-776) 40 50 60 70 80 90 pF1KB0 PEAQPQNSENGALHVTKDLLWEPATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRP ::::::::::::::::::::::: :::::: XP_016 MLPPLIDPWDPGLTARDLLFRGGCRYRKRP 10 20 30 100 110 120 130 140 150 pF1KB0 RVVLDVTEQISRFLLDHGDVAFAPLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVVLDVTEQISRFLLDHGDVAFAPLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGH 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB0 QPWGCPWAYLSNRQRRFSILGGPILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPWGCPWAYLSNRQRRFSILGGPILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALA 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB0 WVPGRTPQFGQLVYPAGGAQDRLHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WVPGRTPQFGQLVYPAGGAQDRLHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQ 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB0 GESKALIYTFLPHWLTCYLTPGPFHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEK ::. ::::::::::::::::::::::::::::::: XP_016 GET--------------------------LLAVRSDYHCAVWKFGKQWQPTLLQAMQVEK 220 230 240 340 350 360 370 380 390 pF1KB0 GATGISLSPHLPGELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GATGISLSPHLPGELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHP 250 260 270 280 290 300 400 410 420 430 440 450 pF1KB0 RVLTVGDRTGVKMLDTQGPPGCGLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVLTVGDRTGVKMLDTQGPPGCGLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLH 310 320 330 340 350 360 460 470 480 490 500 510 pF1KB0 LVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLL 370 380 390 400 410 420 520 530 540 550 560 570 pF1KB0 HLAGEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLAGEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPS 430 440 450 460 470 480 580 590 600 610 620 630 pF1KB0 APTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCS 490 500 510 520 530 540 640 650 660 670 680 690 pF1KB0 QWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDL 550 560 570 580 590 600 700 710 720 730 740 750 pF1KB0 GSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLS 610 620 630 640 650 660 760 770 780 790 800 810 pF1KB0 SSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRD 670 680 690 700 710 720 820 830 840 850 860 pF1KB0 YMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF 730 740 750 760 770 >>XP_016879334 (OMIM: 604905) PREDICTED: TATA box-bindin (843 aa) initn: 5854 init1: 3937 opt: 3937 Z-score: 2688.7 bits: 508.6 E(85289): 5.1e-143 Smith-Waterman score: 5806; 96.8% identity (96.9% similar) in 869 aa overlap (1-869:1-843) 10 20 30 40 50 60 pF1KB0 MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 ATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRPRVVLDVTEQISRFLLDHGDVAFA :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: XP_016 ATPGPLPMLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 PLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 HFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPGP :::::::::::::::::::::::::::::::::::::::. XP_016 HFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGET-------------------- 250 260 270 280 310 320 330 340 350 360 pF1KB0 FHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ------LLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGA 290 300 310 320 330 370 380 390 400 410 420 pF1KB0 VCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB0 LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKW 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB0 NHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRI 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB0 DSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLR 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB0 PQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTH 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB0 RQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSER 640 650 660 670 680 690 730 740 750 760 770 780 pF1KB0 LGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW 700 710 720 730 740 750 790 800 810 820 830 840 pF1KB0 PPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA 760 770 780 790 800 810 850 860 pF1KB0 SSVRATRSQQHTPVLSSSQPLRKKPRMGF ::::::::::::::::::::::::::::: XP_016 SSVRATRSQQHTPVLSSSQPLRKKPRMGF 820 830 840 >>NP_001230085 (OMIM: 604905) TATA box-binding protein-a (843 aa) initn: 5865 init1: 3937 opt: 3937 Z-score: 2688.7 bits: 508.6 E(85289): 5.1e-143 Smith-Waterman score: 5817; 96.9% identity (97.0% similar) in 869 aa overlap (1-869:1-843) 10 20 30 40 50 60 pF1KB0 MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 ATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRPRVVLDVTEQISRFLLDHGDVAFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRPRVVLDVTEQISRFLLDHGDVAFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 PLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 HFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPGP :::::::::::::::::::::::::::::::::::::::. NP_001 HFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGET-------------------- 250 260 270 280 310 320 330 340 350 360 pF1KB0 FHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ------LLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGA 290 300 310 320 330 370 380 390 400 410 420 pF1KB0 VCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB0 LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKW 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB0 NHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRI 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB0 DSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLR 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB0 PQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTH 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB0 RQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSER 640 650 660 670 680 690 730 740 750 760 770 780 pF1KB0 LGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW 700 710 720 730 740 750 790 800 810 820 830 840 pF1KB0 PPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA 760 770 780 790 800 810 850 860 pF1KB0 SSVRATRSQQHTPVLSSSQPLRKKPRMGF ::::::::::::::::::::::::::::: NP_001 SSVRATRSQQHTPVLSSSQPLRKKPRMGF 820 830 840 >>XP_006721389 (OMIM: 604905) PREDICTED: TATA box-bindin (844 aa) initn: 5854 init1: 3937 opt: 3937 Z-score: 2688.7 bits: 508.6 E(85289): 5.1e-143 Smith-Waterman score: 5806; 96.8% identity (96.9% similar) in 869 aa overlap (1-869:2-844) 10 20 30 40 50 pF1KB0 MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MMDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 PATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRPRVVLDVTEQISRFLLDHGDVAF ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_006 PATPGPLPMLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 APLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 PILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 LHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPG ::::::::::::::::::::::::::::::::::::::::. XP_006 LHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGET------------------- 250 260 270 280 300 310 320 330 340 350 pF1KB0 PFHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSG ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 -------LLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSG 290 300 310 320 330 360 370 380 390 400 410 pF1KB0 AVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGC 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB0 GLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLK 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB0 WNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSR 460 470 480 490 500 510 540 550 560 570 580 590 pF1KB0 IDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQL 520 530 540 550 560 570 600 610 620 630 640 650 pF1KB0 RPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFT 580 590 600 610 620 630 660 670 680 690 700 710 pF1KB0 HRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSE 640 650 660 670 680 690 720 730 740 750 760 770 pF1KB0 RLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPE 700 710 720 730 740 750 780 790 800 810 820 830 pF1KB0 WPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQ 760 770 780 790 800 810 840 850 860 pF1KB0 ASSVRATRSQQHTPVLSSSQPLRKKPRMGF :::::::::::::::::::::::::::::: XP_006 ASSVRATRSQQHTPVLSSSQPLRKKPRMGF 820 830 840 >>NP_647610 (OMIM: 604905) TATA box-binding protein-asso (775 aa) initn: 3886 init1: 2432 opt: 3917 Z-score: 2675.6 bits: 506.0 E(85289): 2.7e-142 Smith-Waterman score: 5323; 96.5% identity (96.6% similar) in 802 aa overlap (68-869:1-775) 40 50 60 70 80 90 pF1KB0 PEAQPQNSENGALHVTKDLLWEPATPGPLPMLPPLIDPWDPGLTARDLLFRGGYRYRKRP :::::::::::::::::::::::::::::: NP_647 MLPPLIDPWDPGLTARDLLFRGGYRYRKRP 10 20 30 100 110 120 130 140 150 pF1KB0 RVVLDVTEQISRFLLDHGDVAFAPLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 RVVLDVTEQISRFLLDHGDVAFAPLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGH 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB0 QPWGCPWAYLSNRQRRFSILGGPILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 QPWGCPWAYLSNRQRRFSILGGPILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALA 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB0 WVPGRTPQFGQLVYPAGGAQDRLHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 WVPGRTPQFGQLVYPAGGAQDRLHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQ 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB0 GESKALIYTFLPHWLTCYLTPGPFHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEK ::. ::::::::::::::::::::::::::::::: NP_647 GET--------------------------LLAVRSDYHCAVWKFGKQWQPTLLQAMQVEK 220 230 240 340 350 360 370 380 390 pF1KB0 GATGISLSPHLPGELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 GATGISLSPHLPGELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHP 250 260 270 280 290 300 400 410 420 430 440 450 pF1KB0 RVLTVGDRTGVKMLDTQGPPGCGLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 RVLTVGDRTGVKMLDTQGPPGCGLLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLH 310 320 330 340 350 360 460 470 480 490 500 510 pF1KB0 LVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 LVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLL 370 380 390 400 410 420 520 530 540 550 560 570 pF1KB0 HLAGEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPS ::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 HLA-EGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPS 430 440 450 460 470 480 580 590 600 610 620 630 pF1KB0 APTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 APTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCS 490 500 510 520 530 540 640 650 660 670 680 690 pF1KB0 QWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 QWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDL 550 560 570 580 590 600 700 710 720 730 740 750 pF1KB0 GSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 GSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLS 610 620 630 640 650 660 760 770 780 790 800 810 pF1KB0 SSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 SSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRD 670 680 690 700 710 720 820 830 840 850 860 pF1KB0 YMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_647 YMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF 730 740 750 760 770 869 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:53:24 2016 done: Sat Nov 5 11:53:26 2016 Total Scan time: 16.000 Total Display time: 0.290 Function used was FASTA [36.3.4 Apr, 2011]