FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0442, 902 aa 1>>>pF1KB0442 902 - 902 aa - 902 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.4762+/-0.000433; mu= -15.1939+/- 0.027 mean_var=519.4190+/-108.486, 0's: 0 Z-trim(125.0): 98 B-trim: 895 in 1/58 Lambda= 0.056275 statistics sampled from 47682 (47794) to 47682 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.56), width: 16 Scan time: 17.390 The best scores are: opt bits E(85289) NP_004545 (OMIM: 602699) nuclear factor of activat ( 902) 6348 530.5 1.4e-149 NP_001306972 (OMIM: 602699) nuclear factor of acti ( 965) 6348 530.5 1.5e-149 NP_001129494 (OMIM: 602699) nuclear factor of acti ( 964) 6193 517.9 9.2e-146 XP_011535099 (OMIM: 602699) PREDICTED: nuclear fac ( 890) 6133 513.0 2.5e-144 XP_011535100 (OMIM: 602699) PREDICTED: nuclear fac ( 879) 6130 512.8 3e-144 NP_001275731 (OMIM: 602699) nuclear factor of acti ( 889) 5978 500.4 1.6e-140 NP_001185895 (OMIM: 602699) nuclear factor of acti ( 832) 5835 488.8 4.6e-137 NP_001185894 (OMIM: 602699) nuclear factor of acti ( 794) 5401 453.5 1.8e-126 NP_001185896 (OMIM: 602699) nuclear factor of acti ( 857) 5401 453.6 1.9e-126 XP_011535101 (OMIM: 602699) PREDICTED: nuclear fac ( 782) 5186 436.1 3.2e-121 NP_775186 (OMIM: 602698) nuclear factor of activat (1065) 1660 149.9 6.1e-35 NP_004546 (OMIM: 602698) nuclear factor of activat (1068) 1660 149.9 6.1e-35 NP_775188 (OMIM: 602698) nuclear factor of activat (1075) 1660 149.9 6.1e-35 NP_765975 (OMIM: 600489) nuclear factor of activat ( 930) 1550 140.9 2.7e-32 NP_001265598 (OMIM: 600489) nuclear factor of acti ( 943) 1545 140.5 3.6e-32 NP_765977 (OMIM: 600489) nuclear factor of activat ( 812) 1505 137.2 3e-31 NP_006153 (OMIM: 600489) nuclear factor of activat ( 825) 1500 136.8 4.1e-31 NP_036472 (OMIM: 600490) nuclear factor of activat ( 921) 1449 132.7 7.8e-30 NP_775114 (OMIM: 600490) nuclear factor of activat ( 925) 1449 132.7 7.8e-30 XP_011527126 (OMIM: 600490) PREDICTED: nuclear fac ( 940) 1449 132.7 7.9e-30 NP_001129493 (OMIM: 600490) nuclear factor of acti ( 901) 1447 132.6 8.6e-30 NP_001245221 (OMIM: 600490) nuclear factor of acti ( 905) 1447 132.6 8.6e-30 XP_011527127 (OMIM: 600490) PREDICTED: nuclear fac ( 920) 1447 132.6 8.7e-30 NP_001245225 (OMIM: 600490) nuclear factor of acti ( 702) 1438 131.8 1.2e-29 NP_001245223 (OMIM: 600490) nuclear factor of acti ( 702) 1438 131.8 1.2e-29 NP_001245226 (OMIM: 600490) nuclear factor of acti ( 706) 1438 131.8 1.2e-29 NP_001245224 (OMIM: 600490) nuclear factor of acti ( 706) 1438 131.8 1.2e-29 XP_011527128 (OMIM: 600490) PREDICTED: nuclear fac ( 721) 1438 131.8 1.2e-29 XP_016883339 (OMIM: 600490) PREDICTED: nuclear fac ( 721) 1438 131.8 1.2e-29 NP_001265601 (OMIM: 600489) nuclear factor of acti ( 700) 1420 130.3 3.2e-29 NP_001265604 (OMIM: 600489) nuclear factor of acti ( 703) 1418 130.1 3.6e-29 NP_001265599 (OMIM: 600489) nuclear factor of acti ( 713) 1415 129.9 4.4e-29 NP_765978 (OMIM: 600489) nuclear factor of activat ( 716) 1413 129.7 4.9e-29 XP_016883340 (OMIM: 600490) PREDICTED: nuclear fac ( 695) 1391 127.9 1.6e-28 XP_016881272 (OMIM: 600489) PREDICTED: nuclear fac ( 639) 1223 114.3 2e-24 NP_001265602 (OMIM: 600489) nuclear factor of acti ( 471) 1107 104.7 1.1e-21 NP_765976 (OMIM: 600489) nuclear factor of activat ( 353) 1062 101.0 1.1e-20 XP_016878362 (OMIM: 604708) PREDICTED: nuclear fac (1324) 685 70.8 4.8e-11 XP_011521121 (OMIM: 604708) PREDICTED: nuclear fac (1325) 685 70.8 4.8e-11 XP_011521122 (OMIM: 604708) PREDICTED: nuclear fac (1325) 685 70.8 4.8e-11 XP_016878361 (OMIM: 604708) PREDICTED: nuclear fac (1325) 685 70.8 4.8e-11 XP_011521124 (OMIM: 604708) PREDICTED: nuclear fac (1325) 685 70.8 4.8e-11 XP_016878360 (OMIM: 604708) PREDICTED: nuclear fac (1454) 682 70.6 6.1e-11 XP_016878359 (OMIM: 604708) PREDICTED: nuclear fac (1455) 682 70.6 6.1e-11 NP_775322 (OMIM: 604708) nuclear factor of activat (1455) 682 70.6 6.1e-11 NP_619728 (OMIM: 604708) nuclear factor of activat (1455) 682 70.6 6.1e-11 NP_775321 (OMIM: 604708) nuclear factor of activat (1455) 682 70.6 6.1e-11 XP_011521120 (OMIM: 604708) PREDICTED: nuclear fac (1455) 682 70.6 6.1e-11 XP_006721188 (OMIM: 604708) PREDICTED: nuclear fac (1484) 682 70.6 6.2e-11 XP_011521119 (OMIM: 604708) PREDICTED: nuclear fac (1530) 682 70.6 6.4e-11 >>NP_004545 (OMIM: 602699) nuclear factor of activated T (902 aa) initn: 6348 init1: 6348 opt: 6348 Z-score: 2806.3 bits: 530.5 E(85289): 1.4e-149 Smith-Waterman score: 6348; 100.0% identity (100.0% similar) in 902 aa overlap (1-902:1-902) 10 20 30 40 50 60 pF1KB0 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEP 850 860 870 880 890 900 pF1KB0 PA :: NP_004 PA >>NP_001306972 (OMIM: 602699) nuclear factor of activate (965 aa) initn: 6348 init1: 6348 opt: 6348 Z-score: 2805.9 bits: 530.5 E(85289): 1.5e-149 Smith-Waterman score: 6348; 100.0% identity (100.0% similar) in 902 aa overlap (1-902:64-965) 10 20 30 pF1KB0 MGAASCEDEELEFKLVFGEEKEAPPLGAGG :::::::::::::::::::::::::::::: NP_001 LSKPDFPGNSSPGLPSSSSPGRDLGAPAGSMGAASCEDEELEFKLVFGEEKEAPPLGAGG 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB0 LGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPA 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB0 RSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPE 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB0 GFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFG 220 230 240 250 260 270 220 230 240 250 260 270 pF1KB0 LGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRR 280 290 300 310 320 330 280 290 300 310 320 330 pF1KB0 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKT 340 350 360 370 380 390 340 350 360 370 380 390 pF1KB0 RRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKAR 400 410 420 430 440 450 400 410 420 430 440 450 pF1KB0 IGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHP 460 470 480 490 500 510 460 470 480 490 500 510 pF1KB0 VVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMT 520 530 540 550 560 570 520 530 540 550 560 570 pF1KB0 LLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQA 580 590 600 610 620 630 580 590 600 610 620 630 pF1KB0 ASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQW 640 650 660 670 680 690 640 650 660 670 680 690 pF1KB0 EEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPVICKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPVICKE 700 710 720 730 740 750 700 710 720 730 740 750 pF1KB0 EPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYP 760 770 780 790 800 810 760 770 780 790 800 810 pF1KB0 QTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAP 820 830 840 850 860 870 820 830 840 850 860 870 pF1KB0 FRPPPLPASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRPPPLPASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDS 880 890 900 910 920 930 880 890 900 pF1KB0 VPIQGITLEEVSEIIGRDLSGFPAPPGEEPPA :::::::::::::::::::::::::::::::: NP_001 VPIQGITLEEVSEIIGRDLSGFPAPPGEEPPA 940 950 960 >>NP_001129494 (OMIM: 602699) nuclear factor of activate (964 aa) initn: 6193 init1: 6193 opt: 6193 Z-score: 2737.9 bits: 517.9 E(85289): 9.2e-146 Smith-Waterman score: 6193; 100.0% identity (100.0% similar) in 880 aa overlap (1-880:64-943) 10 20 30 pF1KB0 MGAASCEDEELEFKLVFGEEKEAPPLGAGG :::::::::::::::::::::::::::::: NP_001 LSKPDFPGNSSPGLPSSSSPGRDLGAPAGSMGAASCEDEELEFKLVFGEEKEAPPLGAGG 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB0 LGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPA 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB0 RSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPE 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB0 GFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFG 220 230 240 250 260 270 220 230 240 250 260 270 pF1KB0 LGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRR 280 290 300 310 320 330 280 290 300 310 320 330 pF1KB0 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKT 340 350 360 370 380 390 340 350 360 370 380 390 pF1KB0 RRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKAR 400 410 420 430 440 450 400 410 420 430 440 450 pF1KB0 IGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHP 460 470 480 490 500 510 460 470 480 490 500 510 pF1KB0 VVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMT 520 530 540 550 560 570 520 530 540 550 560 570 pF1KB0 LLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQA 580 590 600 610 620 630 580 590 600 610 620 630 pF1KB0 ASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQW 640 650 660 670 680 690 640 650 660 670 680 690 pF1KB0 EEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPVICKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPVICKE 700 710 720 730 740 750 700 710 720 730 740 750 pF1KB0 EPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYP 760 770 780 790 800 810 760 770 780 790 800 810 pF1KB0 QTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAP 820 830 840 850 860 870 820 830 840 850 860 870 pF1KB0 FRPPPLPASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRPPPLPASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDS 880 890 900 910 920 930 880 890 900 pF1KB0 VPIQGITLEEVSEIIGRDLSGFPAPPGEEPPA :::::::::: NP_001 VPIQGITLEEGGCGTGGCECECVQEIALHVC 940 950 960 >>XP_011535099 (OMIM: 602699) PREDICTED: nuclear factor (890 aa) initn: 6132 init1: 6132 opt: 6133 Z-score: 2712.0 bits: 513.0 E(85289): 2.5e-144 Smith-Waterman score: 6133; 99.2% identity (99.4% similar) in 879 aa overlap (24-902:12-890) 10 20 30 40 50 60 pF1KB0 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG : : . .:::::::::::::::::::::::::::: XP_011 MPASISSIFPGPTLLLSCGSEELDSEDAPPCCRLALGEPPPYGAAPIG 10 20 30 40 70 80 90 100 110 120 pF1KB0 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB0 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB0 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB0 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB0 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB0 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB0 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB0 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB0 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB0 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB0 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB0 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV 710 720 730 740 750 760 790 800 810 820 830 840 pF1KB0 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY 770 780 790 800 810 820 850 860 870 880 890 900 pF1KB0 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEP 830 840 850 860 870 880 pF1KB0 PA :: XP_011 PA 890 >>XP_011535100 (OMIM: 602699) PREDICTED: nuclear factor (879 aa) initn: 6126 init1: 6126 opt: 6130 Z-score: 2710.8 bits: 512.8 E(85289): 3e-144 Smith-Waterman score: 6130; 99.1% identity (99.5% similar) in 878 aa overlap (25-902:2-879) 10 20 30 40 50 60 pF1KB0 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG : . ... ::::::::::::::::::::::::::: XP_011 MPASISSIFPELDSEDAPPCCRLALGEPPPYGAAPIG 10 20 30 70 80 90 100 110 120 pF1KB0 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB0 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB0 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB0 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB0 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB0 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB0 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB0 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB0 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB0 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB0 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP 640 650 660 670 680 690 730 740 750 760 770 780 pF1KB0 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV 700 710 720 730 740 750 790 800 810 820 830 840 pF1KB0 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY 760 770 780 790 800 810 850 860 870 880 890 900 pF1KB0 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEP 820 830 840 850 860 870 pF1KB0 PA :: XP_011 PA >>NP_001275731 (OMIM: 602699) nuclear factor of activate (889 aa) initn: 5977 init1: 5977 opt: 5978 Z-score: 2644.0 bits: 500.4 E(85289): 1.6e-140 Smith-Waterman score: 5978; 99.2% identity (99.4% similar) in 857 aa overlap (24-880:12-868) 10 20 30 40 50 60 pF1KB0 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG : : . .:::::::::::::::::::::::::::: NP_001 MPASISSIFPGPTLLLSCGSEELDSEDAPPCCRLALGEPPPYGAAPIG 10 20 30 40 70 80 90 100 110 120 pF1KB0 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB0 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB0 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB0 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB0 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB0 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB0 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB0 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB0 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB0 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB0 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB0 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV 710 720 730 740 750 760 790 800 810 820 830 840 pF1KB0 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY 770 780 790 800 810 820 850 860 870 880 890 900 pF1KB0 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEVSEIIGRDLSGFPAPPGEEP :::::::::::::::::::::::::::::::::::::::: NP_001 NKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEEGGCGTGGCECECVQEIALHV 830 840 850 860 870 880 pF1KB0 PA NP_001 C >>NP_001185895 (OMIM: 602699) nuclear factor of activate (832 aa) initn: 5835 init1: 5835 opt: 5835 Z-score: 2581.7 bits: 488.8 E(85289): 4.6e-137 Smith-Waterman score: 5835; 100.0% identity (100.0% similar) in 832 aa overlap (71-902:1-832) 50 60 70 80 90 100 pF1KB0 PPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGG :::::::::::::::::::::::::::::: NP_001 MHSPPPRPAPSPGTWESQPARSVRLGGPGG 10 20 30 110 120 130 140 150 160 pF1KB0 GAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGG 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB0 QGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRA 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB0 SPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSA 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB0 SPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVA 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB0 LPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRT 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB0 SALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEK 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB0 PLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAAN 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB0 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQR 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB0 SAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQ 520 530 540 550 560 570 650 660 670 680 690 700 pF1KB0 SNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRG 580 590 600 610 620 630 710 720 730 740 750 760 pF1KB0 FPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRP 640 650 660 670 680 690 770 780 790 800 810 820 pF1KB0 GLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASP 700 710 720 730 740 750 830 840 850 860 870 880 pF1KB0 PLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLEGPFPSQSDVHPLPAEGYNKVGPGYGPGEGAPEQEKSRGGYSSGFRDSVPIQGITLEE 760 770 780 790 800 810 890 900 pF1KB0 VSEIIGRDLSGFPAPPGEEPPA :::::::::::::::::::::: NP_001 VSEIIGRDLSGFPAPPGEEPPA 820 830 >>NP_001185894 (OMIM: 602699) nuclear factor of activate (794 aa) initn: 5542 init1: 5401 opt: 5401 Z-score: 2391.5 bits: 453.5 E(85289): 1.8e-126 Smith-Waterman score: 5401; 100.0% identity (100.0% similar) in 772 aa overlap (1-772:1-772) 10 20 30 40 50 60 pF1KB0 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTVSEIIGRD 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY NP_001 LSGFPAPPGEEPPA 790 >>NP_001185896 (OMIM: 602699) nuclear factor of activate (857 aa) initn: 5542 init1: 5401 opt: 5401 Z-score: 2391.1 bits: 453.6 E(85289): 1.9e-126 Smith-Waterman score: 5401; 100.0% identity (100.0% similar) in 772 aa overlap (1-772:64-835) 10 20 30 pF1KB0 MGAASCEDEELEFKLVFGEEKEAPPLGAGG :::::::::::::::::::::::::::::: NP_001 LSKPDFPGNSSPGLPSSSSPGRDLGAPAGSMGAASCEDEELEFKLVFGEEKEAPPLGAGG 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB0 LGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGEELDSEDAPPCCRLALGEPPPYGAAPIGIPRPPPPRPGMHSPPPRPAPSPGTWESQPA 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB0 RSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSVRLGGPGGGAGGAGGGRVLECPSIRITSISPTPEPPAALEDNPDAWGDGSPRDYPPPE 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB0 GFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFGGYREAGGQGGGAFFSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFG 220 230 240 250 260 270 220 230 240 250 260 270 pF1KB0 LGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGSPLPSPRASPRPWTPEDPWSLYGPSPGGRGPEDSWLLLSAPGPTPASPRPASPCGKRR 280 290 300 310 320 330 280 290 300 310 320 330 pF1KB0 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKT 340 350 360 370 380 390 340 350 360 370 380 390 pF1KB0 RRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRTSSEQAVALPRSEEPASCNGKLPLGAEESVAPPGGSRKEVAGMDYLAVPSPLAWSKAR 400 410 420 430 440 450 400 410 420 430 440 450 pF1KB0 IGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHP 460 470 480 490 500 510 460 470 480 490 500 510 pF1KB0 VVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITGKMVATASYEAVVSGTKVLEMT 520 530 540 550 560 570 520 530 540 550 560 570 pF1KB0 LLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQGGGKVVSVQA 580 590 600 610 620 630 580 590 600 610 620 630 pF1KB0 ASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGSNFLPDSKVVFIERGPDGKLQW 640 650 660 670 680 690 640 650 660 670 680 690 pF1KB0 EEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPVICKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVSNGRRKRSPTQSFRFLPVICKE 700 710 720 730 740 750 700 710 720 730 740 750 pF1KB0 EPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYP 760 770 780 790 800 810 760 770 780 790 800 810 pF1KB0 QTGPPPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLGLPFSPPAP :::::::::::::::::::::: NP_001 QTGPPPSYRPGLRMFPETRGTTVSEIIGRDLSGFPAPPGEEPPA 820 830 840 850 >>XP_011535101 (OMIM: 602699) PREDICTED: nuclear factor (782 aa) initn: 5326 init1: 5185 opt: 5186 Z-score: 2297.3 bits: 436.1 E(85289): 3.2e-121 Smith-Waterman score: 5186; 99.1% identity (99.3% similar) in 749 aa overlap (24-772:12-760) 10 20 30 40 50 60 pF1KB0 MGAASCEDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPIG : : . .:::::::::::::::::::::::::::: XP_011 MPASISSIFPGPTLLLSCGSEELDSEDAPPCCRLALGEPPPYGAAPIG 10 20 30 40 70 80 90 100 110 120 pF1KB0 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPRPPPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGGRVLECPSIRITS 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB0 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISPTPEPPAALEDNPDAWGDGSPRDYPPPEGFGGYREAGGQGGGAFFSPSPGSSSLSSWS 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB0 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWTPEDPWSLYGPSPGG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB0 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGPEDSWLLLSAPGPTPASPRPASPCGKRRYSSSGTPSSASPALSRRGSLGEEGSEPPPP 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB0 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPLPLARDPGSPGPFDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCNGKLPLGAEE 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB0 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVAPPGGSRKEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELR 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB0 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHA 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB0 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYQVHRITGKMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGE 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB0 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDIGRKNTRVRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRG 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB0 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSR 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB0 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVQVYFYVSNGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRP 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB0 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTGCAQPPAV :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYPSYPHEDPACETPYLSEGFGYGMPPLYPQTGPPPSYRPGLRMFPETRGTTVSEIIGRD 710 720 730 740 750 760 790 800 810 820 830 840 pF1KB0 SFLPRPFPSDPYGGRGSSFSLGLPFSPPAPFRPPPLPASPPLEGPFPSQSDVHPLPAEGY XP_011 LSGFPAPPGEEPPA 770 780 902 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:53:19 2016 done: Sat Nov 5 16:53:21 2016 Total Scan time: 17.390 Total Display time: 0.280 Function used was FASTA [36.3.4 Apr, 2011]