FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0447, 501 aa 1>>>pF1KB0447 501 - 501 aa - 501 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8395+/-0.000867; mu= 16.8328+/- 0.052 mean_var=92.8536+/-18.329, 0's: 0 Z-trim(108.7): 23 B-trim: 129 in 1/51 Lambda= 0.133099 statistics sampled from 10396 (10403) to 10396 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.32), width: 16 Scan time: 3.270 The best scores are: opt bits E(32554) CCDS47832.1 CLU gene_id:1191|Hs108|chr8 ( 449) 3016 589.3 2.9e-168 CCDS42405.1 CLUL1 gene_id:27098|Hs108|chr18 ( 466) 332 73.9 4.2e-13 CCDS74187.1 CLUL1 gene_id:27098|Hs108|chr18 ( 518) 332 74.0 4.6e-13 >>CCDS47832.1 CLU gene_id:1191|Hs108|chr8 (449 aa) initn: 3016 init1: 3016 opt: 3016 Z-score: 3134.3 bits: 589.3 E(32554): 2.9e-168 Smith-Waterman score: 3016; 100.0% identity (100.0% similar) in 449 aa overlap (53-501:1-449) 30 40 50 60 70 80 pF1KB0 PSAHNAASPGGARGHRVPLTEACKDSRIGGMMKTLLLFVGLLLTWESGQVLGDQTVSDNE :::::::::::::::::::::::::::::: CCDS47 MMKTLLLFVGLLLTWESGQVLGDQTVSDNE 10 20 30 90 100 110 120 130 140 pF1KB0 LQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB0 SETKLKELPGVCNETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SETKLKELPGVCNETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPF 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB0 YFWMNGDRIDSLLENDRQQTHMLDVMQDHFSRASSIIDELFQDRFFTREPQDTYHYLPFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 YFWMNGDRIDSLLENDRQQTHMLDVMQDHFSRASSIIDELFQDRFFTREPQDTYHYLPFS 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB0 LPHRRPHFFFPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMIHEAQQAMDIHFHSPAFQHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LPHRRPHFFFPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMIHEAQQAMDIHFHSPAFQHP 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB0 PTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRRELDES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRRELDES 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB0 LQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVTTVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVTTVA 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB0 SHTSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRKKHREE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SHTSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRKKHREE 400 410 420 430 440 >>CCDS42405.1 CLUL1 gene_id:27098|Hs108|chr18 (466 aa) initn: 274 init1: 120 opt: 332 Z-score: 348.7 bits: 73.9 E(32554): 4.2e-13 Smith-Waterman score: 566; 25.6% identity (60.1% similar) in 476 aa overlap (53-499:1-464) 30 40 50 60 70 pF1KB0 PSAHNAASPGGARGHRVPLTEACKDSRIGGMMKTLLLFVGLLLTW----ESGQVLGDQTV : ::.:. :: : . . . :.:. CCDS42 MKPPLLVFIVCLL-WLKDSHCAPTWKDKTA 10 20 80 90 100 110 120 130 pF1KB0 SDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALN ...:. .:. : ...:...:..:.::.: ..:. ..:. .:.:.:.. ...:..::. CCDS42 ISENLKSFSEVGEIDADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALK 30 40 50 60 70 80 140 150 160 170 180 190 pF1KB0 ETRESETKLKELPGVCNETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQ : . .:.: .: :.. : ::. ::...::..:. .:. . . : ..:.:. . CCDS42 LLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRIYT-TCQPSWSSVKNKIERFFRK 90 100 110 120 130 140 200 210 220 230 240 250 pF1KB0 SSPFYFWMNGDR------IDSLLENDRQQTHMLDVMQDHFSRASSIIDELFQDRF-FTRE : : .. : ..:.:.: : :.: :: ::. . .. ::. : :. CCDS42 IYQFLFPFHEDNEKDLPISEKLIEEDAQLTQMEDV----FSQLTVDVNSLFNRSFNVFRQ 150 160 170 180 190 200 260 270 280 290 300 pF1KB0 PQDTY------HYLPFSLPHRRPHFF--FPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMI :. . :.. . .:.:: : : .... . : :: .: : : CCDS42 MQQEFDQTFQSHFIS-DTDLTEPYFFPAFSKEPMTKADLEQCWDIP-NFFQLFCNFSVSI 210 220 230 240 250 260 310 320 330 340 350 pF1KB0 HEA---------QQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQC .:. . :. .. : .: .:: .: :. .: . :......: CCDS42 YESVSETITKMLKAIEDLPKQDKAPDHGGLISKMLPGQDRGLCGELDQNLSRCFKFHEKC 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB0 DKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQL .::. :: :: :. :. ::::...... ...:...:. . .. .:. :.:.. CCDS42 QKCQAHLSEDC----PDVPALHTELDEAIRLVNVSNQQYGQILQMTRKHLEDTAYLVEKM 330 340 350 360 370 420 430 440 450 460 470 pF1KB0 NEQFNWVSRLANLTQGEDQYYLRVTTVAS-HTSDSDVPSGVTEVVVKLFDSDPITVTVPV ::.:::.::: . . . . .: : .. . . . . .... :. .:. .:. CCDS42 RGQFGWVSELANQAPETEIIFNSIQVVPRIHEGNISKQDETMMTDLSILPSSNFTLKIPL 380 390 400 410 420 430 480 490 500 pF1KB0 EVSRKNPKFMETVAEKALQEYRKKHREE : : .. .:. :. ::::..... . CCDS42 EESAESSNFIGYVVAKALQHFKEHFKTW 440 450 460 >>CCDS74187.1 CLUL1 gene_id:27098|Hs108|chr18 (518 aa) initn: 274 init1: 120 opt: 332 Z-score: 348.1 bits: 74.0 E(32554): 4.6e-13 Smith-Waterman score: 577; 25.1% identity (58.9% similar) in 514 aa overlap (15-499:15-516) 10 20 30 40 50 60 pF1KB0 MQVCSQPQRGCVREQSAINTAPPSAHNAASPGGARGHRVPLTEACKDSRIGGMMKTLLLF :.... :. . : : . :. . : :.: ::.: CCDS74 MRTWDYRWSLALVAQTGVHCCNLSSLQPLPPRFKRFSCLSLSSGWDYSNSGNMKPPLLVF 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 VGLLLTW----ESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTN . :: : . . . :.:. ...:. .:. : ...:...:..:.::.: ..:. . CCDS74 IVCLL-WLKDSHCAPTWKDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMKIMMERKE 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 EERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQTCMKF .:. .:.:.:.. ...:..::. : . .:.: .: :.. : ::. ::...::.. CCDS74 KEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 YARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDR------IDSLLENDRQQTHMLDVMQD :. .:. . . : ..:.:. . : : .. : ..:.:.: : :.: :: CCDS74 YT-TCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQMEDV--- 180 190 200 210 220 230 240 250 260 270 280 pF1KB0 HFSRASSIIDELFQDRF-FTREPQDTY------HYLPFSLPHRRPHFF--FPKSRIVRSL ::. . .. ::. : :. :. . :.. . .:.:: : : .... CCDS74 -FSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFIS-DTDLTEPYFFPAFSKEPMTKAD 240 250 260 270 280 290 290 300 310 320 330 pF1KB0 MPFSPYEPLNFHAMFQPFLEMIHEA---------QQAMDIHFHSPAFQHPPTEFIREGDD . : :: .: : :.:. . :. .. : .: . CCDS74 LEQCWDIP-NFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAPDHGGLISKMLPGQ 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB0 DRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRK :: .: :. .: . :......:.::. :: :: :. :. ::::...... ... CCDS74 DRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDC----PDVPALHTELDEAIRLVNVSNQQ 360 370 380 390 400 400 410 420 430 440 450 pF1KB0 YNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVTTVAS-HTSDSDVP :...:. . .. .:. :.:.. ::.:::.::: . . . . .: : .. . CCDS74 YGQILQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQVVPRIHEGNISKQ 410 420 430 440 450 460 460 470 480 490 500 pF1KB0 SGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRKKHREE . . . .... :. .:. .:.: : .. .:. :. ::::..... . CCDS74 DETMMTDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQHFKEHFKTW 470 480 490 500 510 501 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:54:30 2016 done: Sat Nov 5 16:54:31 2016 Total Scan time: 3.270 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]