FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0452, 919 aa 1>>>pF1KB0452 919 - 919 aa - 919 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.0061+/-0.00109; mu= -1.9574+/- 0.066 mean_var=433.7384+/-88.953, 0's: 0 Z-trim(115.2): 146 B-trim: 0 in 0/54 Lambda= 0.061583 statistics sampled from 15603 (15748) to 15603 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.484), width: 16 Scan time: 5.390 The best scores are: opt bits E(32554) CCDS14387.1 AR gene_id:367|Hs108|chrX ( 920) 6306 575.3 1.8e-163 CCDS43965.1 AR gene_id:367|Hs108|chrX ( 388) 2608 246.4 7.9e-65 CCDS8310.1 PGR gene_id:5241|Hs108|chr11 ( 933) 1519 150.0 1.9e-35 CCDS4278.1 NR3C1 gene_id:2908|Hs108|chr5 ( 777) 1335 133.6 1.4e-30 CCDS34258.1 NR3C1 gene_id:2908|Hs108|chr5 ( 778) 1330 133.2 1.9e-30 CCDS59229.1 PGR gene_id:5241|Hs108|chr11 ( 339) 1267 127.2 5.3e-29 CCDS47298.1 NR3C1 gene_id:2908|Hs108|chr5 ( 742) 1199 121.5 5.9e-27 CCDS3772.1 NR3C2 gene_id:4306|Hs108|chr4 ( 984) 872 92.6 4e-18 CCDS54811.1 NR3C2 gene_id:4306|Hs108|chr4 ( 867) 696 76.9 1.9e-13 >>CCDS14387.1 AR gene_id:367|Hs108|chrX (920 aa) initn: 3346 init1: 3346 opt: 6306 Z-score: 3048.4 bits: 575.3 E(32554): 1.8e-163 Smith-Waterman score: 6306; 99.7% identity (99.7% similar) in 921 aa overlap (1-919:1-920) 10 20 30 40 50 60 pF1KB0 MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 QQQQQQQQQQQQQQQQQQ--ETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQ :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: CCDS14 QQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 SALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSAD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 LKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELC 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 KAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 KSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB0 SRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAA 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB0 GPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGGEAGAVA ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: CCDS14 GPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGG-EAGAVA 430 440 450 460 470 480 490 500 510 520 530 pF1KB0 PYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMR 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB0 LETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASR 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB0 NDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB0 LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB0 AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKS 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB0 RMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKEL 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB0 DRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEI 840 850 860 870 880 890 900 910 pF1KB0 ISVQVPKILSGKVKPIYFHTQ ::::::::::::::::::::: CCDS14 ISVQVPKILSGKVKPIYFHTQ 900 910 920 >>CCDS43965.1 AR gene_id:367|Hs108|chrX (388 aa) initn: 2608 init1: 2608 opt: 2608 Z-score: 1277.4 bits: 246.4 E(32554): 7.9e-65 Smith-Waterman score: 2608; 100.0% identity (100.0% similar) in 381 aa overlap (539-919:8-388) 510 520 530 540 550 560 pF1KB0 SRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASG :::::::::::::::::::::::::::::: CCDS43 MILWLHSLETARDHVLPIDYYFPPQKTCLICGDEASG 10 20 30 570 580 590 600 610 620 pF1KB0 CHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGA 40 50 60 70 80 90 630 640 650 660 670 680 pF1KB0 RKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAG 100 110 120 130 140 150 690 700 710 720 730 740 pF1KB0 HDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 HDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFA 160 170 180 190 200 210 750 760 770 780 790 800 pF1KB0 MGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMK 220 230 240 250 260 270 810 820 830 840 850 860 pF1KB0 ALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQP 280 290 300 310 320 330 870 880 890 900 910 pF1KB0 IARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 IARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ 340 350 360 370 380 >>CCDS8310.1 PGR gene_id:5241|Hs108|chr11 (933 aa) initn: 1550 init1: 980 opt: 1519 Z-score: 749.8 bits: 150.0 E(32554): 1.9e-35 Smith-Waterman score: 1596; 35.8% identity (60.3% similar) in 950 aa overlap (42-919:46-933) 20 30 40 50 60 pF1KB0 PRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQ--QQQQQQQQQQ ::. :: : . . ::. . : :. .... CCDS83 GGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEV-SAIPISLDGLLFPRPCQGQDPSDEKT 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB0 QQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYL--VLDEEQQPSQPQSALECHPER :.::. .. : . . . .: :: .. . .: : ::: :: : . .: CCDS83 QDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPG---QSQPS- 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB0 GCVPEPGAAVAASKGL-PQQLPAPPDEDDSAAPSTLSLLGPTFP------GLSSCSADLK : :. :..: : .:: :: :::.: .:.: . : :: .: . CCDS83 ---P-PACEVTSSWCLFGPELP----EDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAH 140 150 160 170 180 190 200 210 220 pF1KB0 DILSE--ASTMQLL---------------QQQQQEAVSEGSSSGRAREASGAPT-SSKDN .: . . . ::: . : :: .: : :..: ..: CCDS83 KVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPR 190 200 210 220 230 240 230 240 250 260 pF1KB0 YLGGTSTISDNA---------------KELCKAVSVSMGLGVEALEHLSPGEQLRG---- :::... . : :: . . ..: :: ..::.. . CCDS83 ALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVAL-VEQDAPMAPGRSPLATTVM 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB0 DCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESL : ...:.: . :. . : : .. : .:: .. . : .. : :. CCDS83 DFIHVPILPLNHALLAARTRQLLEDES--YDGGAGAASAFAPPRSSPCASSTPVAVGDFP 310 320 330 340 350 330 340 350 360 370 pF1KB0 GCSGSA-AAGSSGTLEL-----PSTLSLYKSGALDEAAAYQSRDYY---NFPLALAGPPP :. : .. . : : .:.. . ::.: . :.: : :. : CCDS83 DCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPL 360 370 380 390 400 410 380 390 400 410 420 430 pF1KB0 PPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWH :::: : : :. : :. : .:.:.:.: :.:.::. CCDS83 GPPPPLP--------P---------RATPSRPGEAAV-----TAAPASASVSSASSSGST 420 430 440 450 440 450 460 470 480 pF1KB0 T---LFTAE-----EGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPP :. :: .: . : . :..: : . ..... ::: :: : : CCDS83 LECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGA-APALY--PA 460 470 480 490 500 510 490 500 510 520 530 540 pF1KB0 QGLAGQESDFTAPDVWYPGGMVSR-VPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDH :: : :.. : ...... .: : :... : .: .. .. CCDS83 LGLNGL------PQLGYQAAVLKEGLPQVYP--------PYLN-----Y--LRPDSEASQ 520 530 540 550 550 560 570 580 590 600 pF1KB0 VLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDK .. ::: ::::::::::::::.::::::::::::: ::...::::.:::: .:: CCDS83 SPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDK 560 570 580 590 600 610 610 620 630 640 650 pF1KB0 FRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSP------TEETTQKL .::::::.:::::: .:::.::.::.::...... . .: . .: .. .:.. CCDS83 IRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRF 620 630 640 650 660 670 660 670 680 690 700 710 pF1KB0 TVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA : : . . : ..:.: .::: :. :::::..::. ..::.:::.::::::. ::::. CCDS83 TFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWS 680 690 700 710 720 730 720 730 740 750 760 770 pF1KB0 KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSR :.::::::::.:::...::::::.::::..::::. .:...::::::::..:: ::..: CCDS83 KSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESS 740 750 760 770 780 790 780 790 800 810 820 830 pF1KB0 MYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELD .:: :. : .. ::: ::.. .::::::.:::.. ::..::..: :.:.: .::.:: CCDS83 FYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELI 800 810 820 830 840 850 840 850 860 870 880 890 pF1KB0 RIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEII . :. ..:. .: :.::::::::::... ....:: . .. .:.:. .::.:::::.:.: CCDS83 KAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVI 860 870 880 890 900 910 900 910 pF1KB0 SVQVPKILSGKVKPIYFHTQ ..:.::::.: :::. :: . CCDS83 AAQLPKILAGMVKPLLFHKK 920 930 >>CCDS4278.1 NR3C1 gene_id:2908|Hs108|chr5 (777 aa) initn: 1352 init1: 751 opt: 1335 Z-score: 662.4 bits: 133.6 E(32554): 1.4e-30 Smith-Waterman score: 1338; 47.7% identity (73.4% similar) in 436 aa overlap (487-919:368-777) 460 470 480 490 500 510 pF1KB0 GGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSP :: .:... . . .:: : : :: CCDS42 TASLSQQQDQKPIFNVIPPIPVGSENWNRCQG-SGDDNLTSLGTLNFPGRTVFSNGYSSP 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB0 TCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTC . : : : : : .. :. :: : ::.:.:::::::::.::: CCDS42 S-----MRP--DVSSPPSSSSTATTG-----------PPPKLCLVCSDEASGCHYGVLTC 400 410 420 430 580 590 600 610 620 630 pF1KB0 GSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGN ::::::::::.::...::::.:::: :::.::::::.:: ::: .:::.: ::: :: CCDS42 GSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKK--- 440 450 460 470 480 490 640 650 660 670 680 690 pF1KB0 LKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQ :.. : ..::. ..::... :. . : ....::.::: :. ::.:.. CCDS42 -KIK--GIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSV 500 510 520 530 540 550 700 710 720 730 740 750 pF1KB0 PDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRS ::: ....:: :: ::.. .::::::.:::::::.::::...::::: ::.::.:::: CCDS42 PDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRS 560 570 580 590 600 610 760 770 780 790 800 810 pF1KB0 FTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLF . . .. .: :::::..:: :: ::.:: .: ..:.:. ::.. .:.::::.:::. CCDS42 YRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLL 620 630 640 650 660 670 820 830 840 850 860 870 pF1KB0 SIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIAREL : .: ::::.:..:::.::.::::: . :. .. : .. .:::::::::::.. ....: CCDS42 SSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENL 680 690 700 710 720 730 880 890 900 910 pF1KB0 HQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ .. :. .. . : :..::::.::::. :.:: .:..: . :: . CCDS42 LNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 740 750 760 770 >>CCDS34258.1 NR3C1 gene_id:2908|Hs108|chr5 (778 aa) initn: 1151 init1: 751 opt: 1330 Z-score: 660.0 bits: 133.2 E(32554): 1.9e-30 Smith-Waterman score: 1333; 47.8% identity (73.2% similar) in 437 aa overlap (487-919:368-778) 460 470 480 490 500 510 pF1KB0 GGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSP :: .:... . . .:: : : :: CCDS34 TASLSQQQDQKPIFNVIPPIPVGSENWNRCQG-SGDDNLTSLGTLNFPGRTVFSNGYSSP 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB0 TCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTC . : : : : : .. :. :: : ::.:.:::::::::.::: CCDS34 S-----MRP--DVSSPPSSSSTATTG-----------PPPKLCLVCSDEASGCHYGVLTC 400 410 420 430 580 590 600 610 620 630 pF1KB0 GSCKVFFKRAAEGKQK-YLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLG ::::::::::.::.:. ::::.:::: :::.::::::.:: ::: .:::.: ::: :: CCDS34 GSCKVFFKRAVEGRQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKK-- 440 450 460 470 480 490 640 650 660 670 680 690 pF1KB0 NLKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNN :.. : ..::. ..::... :. . : ....::.::: :. ::.:.. CCDS34 --KIK--GIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSS 500 510 520 530 540 550 700 710 720 730 740 750 pF1KB0 QPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWR ::: ....:: :: ::.. .::::::.:::::::.::::...::::: ::.::.::: CCDS34 VPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWR 560 570 580 590 600 610 760 770 780 790 800 810 pF1KB0 SFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLL :. . .. .: :::::..:: :: ::.:: .: ..:.:. ::.. .:.::::.::: CCDS34 SYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLL 620 630 640 650 660 670 820 830 840 850 860 870 pF1KB0 FSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARE .: .: ::::.:..:::.::.::::: . :. .. : .. .:::::::::::.. .... CCDS34 LSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVEN 680 690 700 710 720 730 880 890 900 910 pF1KB0 LHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ : .. :. .. . : :..::::.::::. :.:: .:..: . :: . CCDS34 LLNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 740 750 760 770 >>CCDS59229.1 PGR gene_id:5241|Hs108|chr11 (339 aa) initn: 1232 init1: 980 opt: 1267 Z-score: 634.2 bits: 127.2 E(32554): 5.3e-29 Smith-Waterman score: 1267; 51.8% identity (83.4% similar) in 338 aa overlap (588-919:2-339) 560 570 580 590 600 610 pF1KB0 TCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLR ::...::::.:::: .::.::::::.:::: CCDS59 MEGQHNYLCAGRNDCIVDKIRRKNCPACRLR 10 20 30 620 630 640 650 660 670 pF1KB0 KCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSP------TEETTQKLTVSHIEGYECQP :: .:::.::.::.::...... . .: . .: .. .:..: : . . : CCDS59 KCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIP 40 50 60 70 80 90 680 690 700 710 720 730 pF1KB0 IFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVD ..:.: .::: :. :::::..::. ..::.:::.::::::. ::::.:.::::::::.: CCDS59 PLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHID 100 110 120 130 140 150 740 750 760 770 780 790 pF1KB0 DQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLS ::...::::::.::::..::::. .:...::::::::..:: ::..: .:: :. : .. CCDS59 DQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIP 160 170 180 190 200 210 800 810 820 830 840 850 pF1KB0 QEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTS ::: ::.. .::::::.:::.. ::..::..: :.:.: .::.:: . :. ..:. .: CCDS59 QEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVS 220 230 240 250 260 270 860 870 880 890 900 910 pF1KB0 CSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKV :.::::::::::... ....:: . .. .:.:. .::.:::::.:.:..:.::::.: : CCDS59 SSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMV 280 290 300 310 320 330 pF1KB0 KPIYFHTQ ::. :: . CCDS59 KPLLFHKK >>CCDS47298.1 NR3C1 gene_id:2908|Hs108|chr5 (742 aa) initn: 1229 init1: 729 opt: 1199 Z-score: 597.4 bits: 121.5 E(32554): 5.9e-27 Smith-Waterman score: 1202; 49.2% identity (73.2% similar) in 384 aa overlap (487-867:368-726) 460 470 480 490 500 510 pF1KB0 GGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSP :: .:... . . .:: : : :: CCDS47 TASLSQQQDQKPIFNVIPPIPVGSENWNRCQG-SGDDNLTSLGTLNFPGRTVFSNGYSSP 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB0 TCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTC . : : : : : .. :. :: : ::.:.:::::::::.::: CCDS47 S-----MRP--DVSSPPSSSSTATTG-----------PPPKLCLVCSDEASGCHYGVLTC 400 410 420 430 580 590 600 610 620 630 pF1KB0 GSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGN ::::::::::.::...::::.:::: :::.::::::.:: ::: .:::.: ::: :: CCDS47 GSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKK--- 440 450 460 470 480 490 640 650 660 670 680 690 pF1KB0 LKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQ :.. : ..::. ..::... :. . : ....::.::: :. ::.:.. CCDS47 -KIK--GIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSV 500 510 520 530 540 550 700 710 720 730 740 750 pF1KB0 PDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRS ::: ....:: :: ::.. .::::::.:::::::.::::...::::: ::.::.:::: CCDS47 PDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRS 560 570 580 590 600 610 760 770 780 790 800 810 pF1KB0 FTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLF . . .. .: :::::..:: :: ::.:: .: ..:.:. ::.. .:.::::.:::. CCDS47 YRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLL 620 630 640 650 660 670 820 830 840 850 860 870 pF1KB0 SIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIAREL : .: ::::.:..:::.::.::::: . :. .. : .. .:::::::::::.. CCDS47 SSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHENVMWL 680 690 700 710 720 730 880 890 900 910 pF1KB0 HQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ CCDS47 KPESTSHTLI 740 >>CCDS3772.1 NR3C2 gene_id:4306|Hs108|chr4 (984 aa) initn: 1395 init1: 870 opt: 872 Z-score: 438.9 bits: 92.6 E(32554): 4e-18 Smith-Waterman score: 1328; 51.8% identity (76.9% similar) in 386 aa overlap (555-919:599-984) 530 540 550 560 570 580 pF1KB0 PWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFK :.: ::.:::::::::::..:::::::::: CCDS37 RRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFK 570 580 590 600 610 620 590 600 610 620 630 640 pF1KB0 RAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLK-LQEEG ::.::...::::.:::: :::.::::::.:::.:: .:::.::::: ::::.:: ..:: CCDS37 RAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQ 630 640 650 660 670 680 650 660 670 680 pF1KB0 -----------------EASSTTSPTEE-TTQKLTVSHIE--GYECQPIFLNVLEAIEPG :... .:..: ... : .. . : . ::: ::: CCDS37 PQQQQPPPPPPPPQSPEEGTTYIAPAKEPSVNTALVPQLSTISRALTPSPVMVLENIEPE 690 700 710 720 730 740 690 700 710 720 730 740 pF1KB0 VVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMG .: ::.:...::. :::.::.:. .:...::::::.::::.:: ..::...:::::: CCDS37 IVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMC 750 760 770 780 790 800 750 760 770 780 790 800 pF1KB0 LMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQE : ::..:::. ..::..::::::::::: .::.: :: : :...: .: ::.: .: CCDS37 LSSFALSWRSYKHTNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEE 810 820 830 840 850 860 810 820 830 840 850 860 pF1KB0 FLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL . ::.:::.: :: ::::.: :.:.: :::::: .... .: . .::::::::: CCDS37 YTIMKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLL 870 880 890 900 910 920 870 880 890 900 910 pF1KB0 DSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ ::.. .. .: .: : . .:: ..:.:: :..:::: :.::. ::..::.::: . CCDS37 DSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK 930 940 950 960 970 980 >>CCDS54811.1 NR3C2 gene_id:4306|Hs108|chr4 (867 aa) initn: 1160 init1: 683 opt: 696 Z-score: 355.0 bits: 76.9 E(32554): 1.9e-13 Smith-Waterman score: 931; 43.0% identity (61.4% similar) in 365 aa overlap (555-919:599-867) 530 540 550 560 570 580 pF1KB0 PWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFK :.: ::.:::::::::::..:::::::::: CCDS54 RRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFK 570 580 590 600 610 620 590 600 610 620 630 640 pF1KB0 RAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGE ::.::...::::.:::: :::.::::::.:::.:: .:::.:: CCDS54 RAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLQKCLQAGMNLG----------------- 630 640 650 660 670 650 660 670 680 690 700 pF1KB0 ASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSL CCDS54 ------------------------------------------------------------ 710 720 730 740 750 760 pF1KB0 NELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYF ::.:: ..::...:::::: : ::..:::. ..::..::: CCDS54 -------------------GFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYF 680 690 700 710 770 780 790 800 810 820 pF1KB0 APDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQ :::::::: .::.: :: : :...: .: ::.: .:. ::.:::.: :: ::::.: CCDS54 APDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGLKSQ 720 730 740 750 760 770 830 840 850 860 870 880 pF1KB0 KFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKS :.:.: :::::: .... .: . .:::::::::::.. .. .: .: : . .: CCDS54 AAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSMHDLVSDLLEFCFYTFRES 780 790 800 810 820 830 890 900 910 pF1KB0 HMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ : ..:.:: :..:::: :.::. ::..::.::: . CCDS54 HALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK 840 850 860 919 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 20:34:14 2016 done: Sun Nov 6 20:34:15 2016 Total Scan time: 5.390 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]