FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0452, 919 aa 1>>>pF1KB0452 919 - 919 aa - 919 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.7347+/-0.00043; mu= -0.2676+/- 0.027 mean_var=495.7673+/-102.167, 0's: 0 Z-trim(123.1): 386 B-trim: 0 in 0/58 Lambda= 0.057602 statistics sampled from 41893 (42337) to 41893 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.496), width: 16 Scan time: 16.690 The best scores are: opt bits E(85289) NP_000035 (OMIM: 176807,300068,300633,312300,31320 ( 920) 6306 539.5 2.8e-152 NP_001011645 (OMIM: 176807,300068,300633,312300,31 ( 388) 2608 231.7 5.3e-60 NP_000917 (OMIM: 264080,607311) progesterone recep ( 933) 1519 141.7 1.6e-32 NP_001189403 (OMIM: 264080,607311) progesterone re ( 769) 1500 140.0 4.3e-32 XP_011535939 (OMIM: 138040,615962) PREDICTED: gluc ( 380) 1335 125.9 3.7e-28 NP_001191193 (OMIM: 138040,615962) glucocorticoid ( 442) 1335 126.0 4.1e-28 NP_001191192 (OMIM: 138040,615962) glucocorticoid ( 447) 1335 126.0 4.1e-28 NP_001191191 (OMIM: 138040,615962) glucocorticoid ( 462) 1335 126.0 4.2e-28 NP_001191190 (OMIM: 138040,615962) glucocorticoid ( 680) 1335 126.2 5.3e-28 NP_001191189 (OMIM: 138040,615962) glucocorticoid ( 688) 1335 126.2 5.3e-28 NP_001191188 (OMIM: 138040,615962) glucocorticoid ( 692) 1335 126.3 5.4e-28 NP_001191187 (OMIM: 138040,615962) glucocorticoid ( 751) 1335 126.3 5.6e-28 NP_001018087 (OMIM: 138040,615962) glucocorticoid ( 777) 1335 126.3 5.8e-28 NP_001018084 (OMIM: 138040,615962) glucocorticoid ( 777) 1335 126.3 5.8e-28 XP_016864886 (OMIM: 138040,615962) PREDICTED: gluc ( 777) 1335 126.3 5.8e-28 NP_001018086 (OMIM: 138040,615962) glucocorticoid ( 777) 1335 126.3 5.8e-28 NP_001018085 (OMIM: 138040,615962) glucocorticoid ( 777) 1335 126.3 5.8e-28 XP_016864887 (OMIM: 138040,615962) PREDICTED: gluc ( 777) 1335 126.3 5.8e-28 NP_000167 (OMIM: 138040,615962) glucocorticoid rec ( 777) 1335 126.3 5.8e-28 XP_005268480 (OMIM: 138040,615962) PREDICTED: gluc ( 778) 1330 125.9 7.7e-28 NP_001019265 (OMIM: 138040,615962) glucocorticoid ( 778) 1330 125.9 7.7e-28 XP_005268479 (OMIM: 138040,615962) PREDICTED: gluc ( 778) 1330 125.9 7.7e-28 XP_005268477 (OMIM: 138040,615962) PREDICTED: gluc ( 778) 1330 125.9 7.7e-28 XP_005268476 (OMIM: 138040,615962) PREDICTED: gluc ( 778) 1330 125.9 7.7e-28 NP_001258091 (OMIM: 264080,607311) progesterone re ( 339) 1267 120.2 1.7e-26 NP_001018661 (OMIM: 138040,615962) glucocorticoid ( 742) 1199 115.0 1.4e-24 XP_006718921 (OMIM: 264080,607311) PREDICTED: prog ( 797) 1042 102.0 1.2e-20 NP_001191194 (OMIM: 138040,615962) glucocorticoid ( 676) 1008 99.1 8e-20 NP_000892 (OMIM: 177735,600983,605115) mineralocor ( 984) 872 88.0 2.5e-16 XP_016863706 (OMIM: 177735,600983,605115) PREDICTE ( 984) 872 88.0 2.5e-16 XP_011530277 (OMIM: 177735,600983,605115) PREDICTE ( 988) 872 88.0 2.6e-16 XP_011530278 (OMIM: 177735,600983,605115) PREDICTE ( 988) 872 88.0 2.6e-16 XP_011530279 (OMIM: 177735,600983,605115) PREDICTE ( 988) 872 88.0 2.6e-16 NP_001258090 (OMIM: 264080,607311) progesterone re ( 667) 786 80.6 2.8e-14 NP_001159576 (OMIM: 177735,600983,605115) mineralo ( 867) 696 73.3 6e-12 XP_016876569 (OMIM: 601663) PREDICTED: estrogen re ( 530) 541 60.1 3.3e-08 XP_016876570 (OMIM: 601663) PREDICTED: estrogen re ( 530) 541 60.1 3.3e-08 XP_016876572 (OMIM: 601663) PREDICTED: estrogen re ( 530) 541 60.1 3.3e-08 NP_001428 (OMIM: 601663) estrogen receptor beta is ( 530) 541 60.1 3.3e-08 XP_016876568 (OMIM: 601663) PREDICTED: estrogen re ( 530) 541 60.1 3.3e-08 XP_016876571 (OMIM: 601663) PREDICTED: estrogen re ( 530) 541 60.1 3.3e-08 NP_001258805 (OMIM: 601663) estrogen receptor beta ( 474) 538 59.8 3.7e-08 NP_001201831 (OMIM: 601663) estrogen receptor beta ( 481) 538 59.8 3.7e-08 NP_001278652 (OMIM: 601663) estrogen receptor beta ( 495) 538 59.8 3.8e-08 NP_001035365 (OMIM: 601663) estrogen receptor beta ( 495) 538 59.8 3.8e-08 NP_001278641 (OMIM: 601663) estrogen receptor beta ( 495) 538 59.8 3.8e-08 XP_016876573 (OMIM: 601663) PREDICTED: estrogen re ( 495) 538 59.8 3.8e-08 XP_011507580 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 529 59.0 5.9e-08 XP_016856124 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 529 59.0 5.9e-08 XP_011507579 (OMIM: 602969) PREDICTED: estrogen-re ( 442) 529 59.0 5.9e-08 >>NP_000035 (OMIM: 176807,300068,300633,312300,313200,31 (920 aa) initn: 3346 init1: 3346 opt: 6306 Z-score: 2854.8 bits: 539.5 E(85289): 2.8e-152 Smith-Waterman score: 6306; 99.7% identity (99.7% similar) in 921 aa overlap (1-919:1-920) 10 20 30 40 50 60 pF1KB0 MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 QQQQQQQQQQQQQQQQQQ--ETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQ :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: NP_000 QQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 SALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSAD 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 LKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELC 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 KAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAG 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 KSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQ 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB0 SRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAA 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB0 GPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGGEAGAVA ::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::: NP_000 GPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGG-EAGAVA 430 440 450 460 470 480 490 500 510 520 530 pF1KB0 PYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMR 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB0 LETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASR 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB0 NDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQK 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB0 LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB0 AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKS 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB0 RMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKEL 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB0 DRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEI 840 850 860 870 880 890 900 910 pF1KB0 ISVQVPKILSGKVKPIYFHTQ ::::::::::::::::::::: NP_000 ISVQVPKILSGKVKPIYFHTQ 900 910 920 >>NP_001011645 (OMIM: 176807,300068,300633,312300,313200 (388 aa) initn: 2608 init1: 2608 opt: 2608 Z-score: 1198.1 bits: 231.7 E(85289): 5.3e-60 Smith-Waterman score: 2608; 100.0% identity (100.0% similar) in 381 aa overlap (539-919:8-388) 510 520 530 540 550 560 pF1KB0 SRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASG :::::::::::::::::::::::::::::: NP_001 MILWLHSLETARDHVLPIDYYFPPQKTCLICGDEASG 10 20 30 570 580 590 600 610 620 pF1KB0 CHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGA 40 50 60 70 80 90 630 640 650 660 670 680 pF1KB0 RKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAG 100 110 120 130 140 150 690 700 710 720 730 740 pF1KB0 HDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFA 160 170 180 190 200 210 750 760 770 780 790 800 pF1KB0 MGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMK 220 230 240 250 260 270 810 820 830 840 850 860 pF1KB0 ALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQP 280 290 300 310 320 330 870 880 890 900 910 pF1KB0 IARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ 340 350 360 370 380 >>NP_000917 (OMIM: 264080,607311) progesterone receptor (933 aa) initn: 1550 init1: 980 opt: 1519 Z-score: 704.8 bits: 141.7 E(85289): 1.6e-32 Smith-Waterman score: 1596; 35.8% identity (60.3% similar) in 950 aa overlap (42-919:46-933) 20 30 40 50 60 pF1KB0 PRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQ--QQQQQQQQQQ ::. :: : . . ::. . : :. .... NP_000 GGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEV-SAIPISLDGLLFPRPCQGQDPSDEKT 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB0 QQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYL--VLDEEQQPSQPQSALECHPER :.::. .. : . . . .: :: .. . .: : ::: :: : . .: NP_000 QDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPG---QSQPS- 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB0 GCVPEPGAAVAASKGL-PQQLPAPPDEDDSAAPSTLSLLGPTFP------GLSSCSADLK : :. :..: : .:: :: :::.: .:.: . : :: .: . NP_000 ---P-PACEVTSSWCLFGPELP----EDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAH 140 150 160 170 180 190 200 210 220 pF1KB0 DILSE--ASTMQLL---------------QQQQQEAVSEGSSSGRAREASGAPT-SSKDN .: . . . ::: . : :: .: : :..: ..: NP_000 KVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPR 190 200 210 220 230 240 230 240 250 260 pF1KB0 YLGGTSTISDNA---------------KELCKAVSVSMGLGVEALEHLSPGEQLRG---- :::... . : :: . . ..: :: ..::.. . NP_000 ALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVAL-VEQDAPMAPGRSPLATTVM 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB0 DCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESL : ...:.: . :. . : : .. : .:: .. . : .. : :. NP_000 DFIHVPILPLNHALLAARTRQLLEDES--YDGGAGAASAFAPPRSSPCASSTPVAVGDFP 310 320 330 340 350 330 340 350 360 370 pF1KB0 GCSGSA-AAGSSGTLEL-----PSTLSLYKSGALDEAAAYQSRDYY---NFPLALAGPPP :. : .. . : : .:.. . ::.: . :.: : :. : NP_000 DCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPL 360 370 380 390 400 410 380 390 400 410 420 430 pF1KB0 PPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWH :::: : : :. : :. : .:.:.:.: :.:.::. NP_000 GPPPPLP--------P---------RATPSRPGEAAV-----TAAPASASVSSASSSGST 420 430 440 450 440 450 460 470 480 pF1KB0 T---LFTAE-----EGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPP :. :: .: . : . :..: : . ..... ::: :: : : NP_000 LECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGA-APALY--PA 460 470 480 490 500 510 490 500 510 520 530 540 pF1KB0 QGLAGQESDFTAPDVWYPGGMVSR-VPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDH :: : :.. : ...... .: : :... : .: .. .. NP_000 LGLNGL------PQLGYQAAVLKEGLPQVYP--------PYLN-----Y--LRPDSEASQ 520 530 540 550 550 560 570 580 590 600 pF1KB0 VLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDK .. ::: ::::::::::::::.::::::::::::: ::...::::.:::: .:: NP_000 SPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDK 560 570 580 590 600 610 610 620 630 640 650 pF1KB0 FRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSP------TEETTQKL .::::::.:::::: .:::.::.::.::...... . .: . .: .. .:.. NP_000 IRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRF 620 630 640 650 660 670 660 670 680 690 700 710 pF1KB0 TVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA : : . . : ..:.: .::: :. :::::..::. ..::.:::.::::::. ::::. NP_000 TFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWS 680 690 700 710 720 730 720 730 740 750 760 770 pF1KB0 KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSR :.::::::::.:::...::::::.::::..::::. .:...::::::::..:: ::..: NP_000 KSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESS 740 750 760 770 780 790 780 790 800 810 820 830 pF1KB0 MYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELD .:: :. : .. ::: ::.. .::::::.:::.. ::..::..: :.:.: .::.:: NP_000 FYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELI 800 810 820 830 840 850 840 850 860 870 880 890 pF1KB0 RIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEII . :. ..:. .: :.::::::::::... ....:: . .. .:.:. .::.:::::.:.: NP_000 KAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVI 860 870 880 890 900 910 900 910 pF1KB0 SVQVPKILSGKVKPIYFHTQ ..:.::::.: :::. :: . NP_000 AAQLPKILAGMVKPLLFHKK 920 930 >>NP_001189403 (OMIM: 264080,607311) progesterone recept (769 aa) initn: 1517 init1: 980 opt: 1500 Z-score: 697.2 bits: 140.0 E(85289): 4.3e-32 Smith-Waterman score: 1557; 37.2% identity (63.4% similar) in 830 aa overlap (128-919:5-769) 100 110 120 130 140 150 pF1KB0 HRRGPTGYLVLDEEQQPSQPQSALECHPERGC-VPEPGAAVAASKGLPQQL-PA-----P :: : . ....:: : ::. : :: : NP_001 MSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLP 10 20 30 160 170 180 190 200 pF1KB0 PDEDD--SAAPSTLSLLGPTFPGLSSCSADLKD-ILSEASTMQLLQQQQQEAVSEGSSSG .:. :.:: . :. : .. .. .: :: :. ::. . . . ....: NP_001 ASESPHWSGAP-----VKPS-PQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGG 40 50 60 70 80 210 220 230 240 250 260 pF1KB0 RAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRG---- : :: . ::.. . . ... .: :.. :: ..::.. . NP_001 AAAVPPGAAA-------GGVALVPKEDSRF-SAPRVAL---VEQDAPMAPGRSPLATTVM 90 100 110 120 130 270 280 290 300 310 320 pF1KB0 DCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESL : ...:.: . :. . : : .. : .:: .. . : .. : :. NP_001 DFIHVPILPLNHALLAARTRQLLEDES--YDGGAGAASAFAPPRSSPCASSTPVAVGDFP 140 150 160 170 180 190 330 340 350 360 370 pF1KB0 GCSGSA-AAGSSGTLEL-----PSTLSLYKSGALDEAAAYQSRDYY---NFPLALAGPPP :. : .. . : : .:.. . ::.: . :.: : :. : NP_001 DCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPL 200 210 220 230 240 250 380 390 400 410 420 430 pF1KB0 PPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWH :::: : : :. : :. : .:.:.:.: :.:.::. NP_001 GPPPPLP--------P---------RATPSRPGEAAV-----TAAPASASVSSASSSGST 260 270 280 290 440 450 460 470 480 pF1KB0 T---LFTAE-----EGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPP :. :: .: . : . :..: : . ..... ::: :: : : NP_001 LECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGA-APALY--PA 300 310 320 330 340 350 490 500 510 520 530 540 pF1KB0 QGLAGQESDFTAPDVWYPGGMVSR-VPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDH :: : :.. : ...... .: : :... : .: .. .. NP_001 LGLNG------LPQLGYQAAVLKEGLPQVYP--------PYLN-Y------LRPDSEASQ 360 370 380 550 560 570 580 590 600 pF1KB0 VLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDK .. ::: ::::::::::::::.::::::::::::: ::...::::.:::: .:: NP_001 SPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDK 390 400 410 420 430 440 610 620 630 640 650 pF1KB0 FRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSP------TEETTQKL .::::::.:::::: .:::.::.::.::...... . .: . .: .. .:.. NP_001 IRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRF 450 460 470 480 490 500 660 670 680 690 700 710 pF1KB0 TVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA : : . . : ..:.: .::: :. :::::..::. ..::.:::.::::::. ::::. NP_001 TFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWS 510 520 530 540 550 560 720 730 740 750 760 770 pF1KB0 KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSR :.::::::::.:::...::::::.::::..::::. .:...::::::::..:: ::..: NP_001 KSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESS 570 580 590 600 610 620 780 790 800 810 820 830 pF1KB0 MYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELD .:: :. : .. ::: ::.. .::::::.:::.. ::..::..: :.:.: .::.:: NP_001 FYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELI 630 640 650 660 670 680 840 850 860 870 880 890 pF1KB0 RIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEII . :. ..:. .: :.::::::::::... ....:: . .. .:.:. .::.:::::.:.: NP_001 KAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVI 690 700 710 720 730 740 900 910 pF1KB0 SVQVPKILSGKVKPIYFHTQ ..:.::::.: :::. :: . NP_001 AAQLPKILAGMVKPLLFHKK 750 760 >>XP_011535939 (OMIM: 138040,615962) PREDICTED: glucocor (380 aa) initn: 1311 init1: 751 opt: 1335 Z-score: 626.5 bits: 125.9 E(85289): 3.7e-28 Smith-Waterman score: 1335; 52.3% identity (79.7% similar) in 369 aa overlap (554-919:19-380) 530 540 550 560 570 580 pF1KB0 GPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFF :: : ::.:.:::::::::.:::::::::: XP_011 MRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFF 10 20 30 40 590 600 610 620 630 640 pF1KB0 KRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEG :::.::...::::.:::: :::.::::::.:: ::: .:::.: ::: :: :.. : XP_011 KRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKK----KIK--G 50 60 70 80 90 100 650 660 670 680 690 700 pF1KB0 EASSTTSPTEETTQK---LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAAL ..::. ..::... :. . : ....::.::: :. ::.:.. ::: . XP_011 IQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRI 110 120 130 140 150 160 710 720 730 740 750 760 pF1KB0 LSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSR ...:: :: ::.. .::::::.:::::::.::::...::::: ::.::.::::. . .. XP_011 MTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSAN 170 180 190 200 210 220 770 780 790 800 810 820 pF1KB0 MLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG .: :::::..:: :: ::.:: .: ..:.:. ::.. .:.::::.:::.: .: :: XP_011 LLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDG 230 240 250 260 270 280 830 840 850 860 870 880 pF1KB0 LKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDL ::.:..:::.::.::::: . :. .. : .. .:::::::::::.. ....: .. :. XP_011 LKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQT 290 300 310 320 330 340 890 900 910 pF1KB0 LIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ .. . : :..::::.::::. :.:: .:..: . :: . XP_011 FLDKTM-SIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 350 360 370 380 >>NP_001191193 (OMIM: 138040,615962) glucocorticoid rece (442 aa) initn: 1311 init1: 751 opt: 1335 Z-score: 625.8 bits: 126.0 E(85289): 4.1e-28 Smith-Waterman score: 1338; 47.7% identity (73.4% similar) in 436 aa overlap (487-919:33-442) 460 470 480 490 500 510 pF1KB0 GGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSP :: .:... . . .:: : : :: NP_001 TASLSQQQDQKPIFNVIPPIPVGSENWNRCQG-SGDDNLTSLGTLNFPGRTVFSNGYSSP 10 20 30 40 50 60 520 530 540 550 560 570 pF1KB0 TCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTC . : : : : : .. :. :: : ::.:.:::::::::.::: NP_001 S-----MRP--DVSSPPSSSSTATTG-----------PPPKLCLVCSDEASGCHYGVLTC 70 80 90 100 580 590 600 610 620 630 pF1KB0 GSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGN ::::::::::.::...::::.:::: :::.::::::.:: ::: .:::.: ::: :: NP_001 GSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKK--- 110 120 130 140 150 160 640 650 660 670 680 690 pF1KB0 LKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQ :.. : ..::. ..::... :. . : ....::.::: :. ::.:.. NP_001 -KIK--GIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSV 170 180 190 200 210 700 710 720 730 740 750 pF1KB0 PDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRS ::: ....:: :: ::.. .::::::.:::::::.::::...::::: ::.::.:::: NP_001 PDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRS 220 230 240 250 260 270 760 770 780 790 800 810 pF1KB0 FTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLF . . .. .: :::::..:: :: ::.:: .: ..:.:. ::.. .:.::::.:::. NP_001 YRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLL 280 290 300 310 320 330 820 830 840 850 860 870 pF1KB0 SIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIAREL : .: ::::.:..:::.::.::::: . :. .. : .. .:::::::::::.. ....: NP_001 SSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENL 340 350 360 370 380 390 880 890 900 910 pF1KB0 HQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ .. :. .. . : :..::::.::::. :.:: .:..: . :: . NP_001 LNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 400 410 420 430 440 >>NP_001191192 (OMIM: 138040,615962) glucocorticoid rece (447 aa) initn: 1311 init1: 751 opt: 1335 Z-score: 625.7 bits: 126.0 E(85289): 4.1e-28 Smith-Waterman score: 1338; 47.7% identity (73.4% similar) in 436 aa overlap (487-919:38-447) 460 470 480 490 500 510 pF1KB0 GGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSP :: .:... . . .:: : : :: NP_001 TASLSQQQDQKPIFNVIPPIPVGSENWNRCQG-SGDDNLTSLGTLNFPGRTVFSNGYSSP 10 20 30 40 50 60 520 530 540 550 560 570 pF1KB0 TCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTC . : : : : : .. :. :: : ::.:.:::::::::.::: NP_001 S-----MRP--DVSSPPSSSSTATTG-----------PPPKLCLVCSDEASGCHYGVLTC 70 80 90 100 580 590 600 610 620 630 pF1KB0 GSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGN ::::::::::.::...::::.:::: :::.::::::.:: ::: .:::.: ::: :: NP_001 GSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKK--- 110 120 130 140 150 160 640 650 660 670 680 690 pF1KB0 LKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQ :.. : ..::. ..::... :. . : ....::.::: :. ::.:.. NP_001 -KIK--GIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSV 170 180 190 200 210 220 700 710 720 730 740 750 pF1KB0 PDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRS ::: ....:: :: ::.. .::::::.:::::::.::::...::::: ::.::.:::: NP_001 PDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRS 230 240 250 260 270 280 760 770 780 790 800 810 pF1KB0 FTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLF . . .. .: :::::..:: :: ::.:: .: ..:.:. ::.. .:.::::.:::. NP_001 YRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLL 290 300 310 320 330 340 820 830 840 850 860 870 pF1KB0 SIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIAREL : .: ::::.:..:::.::.::::: . :. .. : .. .:::::::::::.. ....: NP_001 SSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENL 350 360 370 380 390 400 880 890 900 910 pF1KB0 HQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ .. :. .. . : :..::::.::::. :.:: .:..: . :: . NP_001 LNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 410 420 430 440 >>NP_001191191 (OMIM: 138040,615962) glucocorticoid rece (462 aa) initn: 1311 init1: 751 opt: 1335 Z-score: 625.6 bits: 126.0 E(85289): 4.2e-28 Smith-Waterman score: 1338; 47.7% identity (73.4% similar) in 436 aa overlap (487-919:53-462) 460 470 480 490 500 510 pF1KB0 GGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSP :: .:... . . .:: : : :: NP_001 TASLSQQQDQKPIFNVIPPIPVGSENWNRCQG-SGDDNLTSLGTLNFPGRTVFSNGYSSP 30 40 50 60 70 80 520 530 540 550 560 570 pF1KB0 TCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTC . : : : : : .. :. :: : ::.:.:::::::::.::: NP_001 S-----MRP--DVSSPPSSSSTATTG-----------PPPKLCLVCSDEASGCHYGVLTC 90 100 110 120 580 590 600 610 620 630 pF1KB0 GSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGN ::::::::::.::...::::.:::: :::.::::::.:: ::: .:::.: ::: :: NP_001 GSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKK--- 130 140 150 160 170 180 640 650 660 670 680 690 pF1KB0 LKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQ :.. : ..::. ..::... :. . : ....::.::: :. ::.:.. NP_001 -KIK--GIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSV 190 200 210 220 230 700 710 720 730 740 750 pF1KB0 PDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRS ::: ....:: :: ::.. .::::::.:::::::.::::...::::: ::.::.:::: NP_001 PDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRS 240 250 260 270 280 290 760 770 780 790 800 810 pF1KB0 FTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLF . . .. .: :::::..:: :: ::.:: .: ..:.:. ::.. .:.::::.:::. NP_001 YRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLL 300 310 320 330 340 350 820 830 840 850 860 870 pF1KB0 SIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIAREL : .: ::::.:..:::.::.::::: . :. .. : .. .:::::::::::.. ....: NP_001 SSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENL 360 370 380 390 400 410 880 890 900 910 pF1KB0 HQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ .. :. .. . : :..::::.::::. :.:: .:..: . :: . NP_001 LNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 420 430 440 450 460 >>NP_001191190 (OMIM: 138040,615962) glucocorticoid rece (680 aa) initn: 1343 init1: 751 opt: 1335 Z-score: 623.7 bits: 126.2 E(85289): 5.3e-28 Smith-Waterman score: 1338; 47.7% identity (73.4% similar) in 436 aa overlap (487-919:271-680) 460 470 480 490 500 510 pF1KB0 GGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSP :: .:... . . .:: : : :: NP_001 TASLSQQQDQKPIFNVIPPIPVGSENWNRCQG-SGDDNLTSLGTLNFPGRTVFSNGYSSP 250 260 270 280 290 520 530 540 550 560 570 pF1KB0 TCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTC . : : : : : .. :. :: : ::.:.:::::::::.::: NP_001 S-----MRP--DVSSPPSSSSTATTG-----------PPPKLCLVCSDEASGCHYGVLTC 300 310 320 330 340 580 590 600 610 620 630 pF1KB0 GSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGN ::::::::::.::...::::.:::: :::.::::::.:: ::: .:::.: ::: :: NP_001 GSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKK--- 350 360 370 380 390 640 650 660 670 680 690 pF1KB0 LKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQ :.. : ..::. ..::... :. . : ....::.::: :. ::.:.. NP_001 -KIK--GIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSV 400 410 420 430 440 450 700 710 720 730 740 750 pF1KB0 PDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRS ::: ....:: :: ::.. .::::::.:::::::.::::...::::: ::.::.:::: NP_001 PDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRS 460 470 480 490 500 510 760 770 780 790 800 810 pF1KB0 FTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLF . . .. .: :::::..:: :: ::.:: .: ..:.:. ::.. .:.::::.:::. NP_001 YRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLL 520 530 540 550 560 570 820 830 840 850 860 870 pF1KB0 SIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIAREL : .: ::::.:..:::.::.::::: . :. .. : .. .:::::::::::.. ....: NP_001 SSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENL 580 590 600 610 620 630 880 890 900 910 pF1KB0 HQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ .. :. .. . : :..::::.::::. :.:: .:..: . :: . NP_001 LNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 640 650 660 670 680 >>NP_001191189 (OMIM: 138040,615962) glucocorticoid rece (688 aa) initn: 1343 init1: 751 opt: 1335 Z-score: 623.7 bits: 126.2 E(85289): 5.3e-28 Smith-Waterman score: 1338; 47.7% identity (73.4% similar) in 436 aa overlap (487-919:279-688) 460 470 480 490 500 510 pF1KB0 GGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSP :: .:... . . .:: : : :: NP_001 TASLSQQQDQKPIFNVIPPIPVGSENWNRCQG-SGDDNLTSLGTLNFPGRTVFSNGYSSP 250 260 270 280 290 300 520 530 540 550 560 570 pF1KB0 TCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTC . : : : : : .. :. :: : ::.:.:::::::::.::: NP_001 S-----MRP--DVSSPPSSSSTATTG-----------PPPKLCLVCSDEASGCHYGVLTC 310 320 330 340 580 590 600 610 620 630 pF1KB0 GSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGN ::::::::::.::...::::.:::: :::.::::::.:: ::: .:::.: ::: :: NP_001 GSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKK--- 350 360 370 380 390 400 640 650 660 670 680 690 pF1KB0 LKLQEEGEASSTTSPTEETTQK---LTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQ :.. : ..::. ..::... :. . : ....::.::: :. ::.:.. NP_001 -KIK--GIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSV 410 420 430 440 450 460 700 710 720 730 740 750 pF1KB0 PDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRS ::: ....:: :: ::.. .::::::.:::::::.::::...::::: ::.::.:::: NP_001 PDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRS 470 480 490 500 510 520 760 770 780 790 800 810 pF1KB0 FTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLF . . .. .: :::::..:: :: ::.:: .: ..:.:. ::.. .:.::::.:::. NP_001 YRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLL 530 540 550 560 570 580 820 830 840 850 860 870 pF1KB0 SIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIAREL : .: ::::.:..:::.::.::::: . :. .. : .. .:::::::::::.. ....: NP_001 SSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENL 590 600 610 620 630 640 880 890 900 910 pF1KB0 HQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ .. :. .. . : :..::::.::::. :.:: .:..: . :: . NP_001 LNYCFQTFLDKTM-SIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK 650 660 670 680 919 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 20:34:15 2016 done: Sun Nov 6 20:34:18 2016 Total Scan time: 16.690 Total Display time: 0.210 Function used was FASTA [36.3.4 Apr, 2011]