FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0469, 515 aa 1>>>pF1KB0469 515 - 515 aa - 515 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.7591+/-0.00047; mu= -4.3346+/- 0.029 mean_var=384.5035+/-79.835, 0's: 0 Z-trim(121.5): 12 B-trim: 689 in 1/54 Lambda= 0.065407 statistics sampled from 38087 (38099) to 38087 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.447), width: 16 Scan time: 9.600 The best scores are: opt bits E(85289) NP_003067 (OMIM: 601735) SWI/SNF-related matrix-as ( 515) 3483 342.7 1.5e-93 NP_620710 (OMIM: 601735) SWI/SNF-related matrix-as ( 474) 2857 283.6 8.6e-76 NP_001003802 (OMIM: 601737) SWI/SNF-related matrix ( 470) 2363 237.0 9.2e-62 NP_003069 (OMIM: 601737) SWI/SNF-related matrix-as ( 470) 2363 237.0 9.2e-62 NP_001003801 (OMIM: 601737) SWI/SNF-related matrix ( 483) 2356 236.4 1.5e-61 NP_001091896 (OMIM: 601736) SWI/SNF-related matrix ( 531) 2164 218.3 4.5e-56 XP_011514823 (OMIM: 601737) PREDICTED: SWI/SNF-rel ( 381) 2127 214.7 4e-55 NP_001317369 (OMIM: 601736) SWI/SNF-related matrix ( 483) 2110 213.2 1.4e-54 NP_001317368 (OMIM: 601736) SWI/SNF-related matrix ( 456) 2078 210.1 1.1e-53 XP_005269164 (OMIM: 601735) PREDICTED: SWI/SNF-rel ( 474) 2029 205.5 2.8e-52 XP_011536997 (OMIM: 601735) PREDICTED: SWI/SNF-rel ( 265) 1734 177.4 4.5e-44 XP_016868045 (OMIM: 601737) PREDICTED: SWI/SNF-rel ( 318) 1612 166.0 1.5e-40 >>NP_003067 (OMIM: 601735) SWI/SNF-related matrix-associ (515 aa) initn: 3483 init1: 3483 opt: 3483 Z-score: 1800.5 bits: 342.7 E(85289): 1.5e-93 Smith-Waterman score: 3483; 100.0% identity (100.0% similar) in 515 aa overlap (1-515:1-515) 10 20 30 40 50 60 pF1KB0 MAARAGFQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MAARAGFQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 PGMLPGSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PGMLPGSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 HNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 KLRIFISNTFNPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KLRIFISNTFNPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 VIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 LARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LHALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LHALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 DNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAE 430 440 450 460 470 480 490 500 510 pF1KB0 FYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT ::::::::::::::::::::::::::::::::::: NP_003 FYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT 490 500 510 >>NP_620710 (OMIM: 601735) SWI/SNF-related matrix-associ (474 aa) initn: 2940 init1: 2857 opt: 2857 Z-score: 1481.7 bits: 283.6 E(85289): 8.6e-76 Smith-Waterman score: 3110; 92.0% identity (92.0% similar) in 515 aa overlap (1-515:1-474) 10 20 30 40 50 60 pF1KB0 MAARAGFQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MAARAGFQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 PGMLPGSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 PGMLPGSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 HNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 HNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 KLRIFISNTFNPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 KLRIFISNTFNPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 VIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 VIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 LARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 LARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LHALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 LHALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 DNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAE ::: :::::::::::::::: NP_620 DNK-----------------------------------------TMTDVVGNPEEERRAE 430 490 500 510 pF1KB0 FYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT ::::::::::::::::::::::::::::::::::: NP_620 FYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT 440 450 460 470 >>NP_001003802 (OMIM: 601737) SWI/SNF-related matrix-ass (470 aa) initn: 1822 init1: 1619 opt: 2363 Z-score: 1229.8 bits: 237.0 E(85289): 9.2e-62 Smith-Waterman score: 2363; 74.1% identity (88.0% similar) in 475 aa overlap (54-515:3-470) 30 40 50 60 70 pF1KB0 AAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYP-----RPGMLPGSRMTPQGPSMGP :: .: :::: :.:: :: ::: NP_001 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGP 10 20 30 80 90 100 110 120 130 pF1KB0 PG--YGGNPSVRPGLAQSGMDQSRKR--PAPQQIQ-QVQQQAVQN---RNHNAKKKKMAD :: : :.:.:::::: .::. .::: : : : : : : : : . :...::..:::: NP_001 PGSPYMGSPAVRPGLAPAGMEPARKRAAPPPGQSQAQSQGQPVPTAPARSRSAKRRKMAD 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB0 KILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTF :::::::::::::::::::::::::::::::::::.:::::::::.:::::::..::::: NP_001 KILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTF 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB0 NPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYG :::: ::::..:..:::::::::.::.: .::::::::::::::::::::::: NP_001 NPAKPDAEDSDGSIASWELRVEGKLLDDP-------SKQKRKFSSFFKSLVIELDKDLYG 160 170 180 190 200 260 270 280 290 300 310 pF1KB0 PDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQ ::::::::::: :::::::::::::::..::::.::::::::::::::::::::::.::: NP_001 PDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQ 210 220 230 240 250 260 320 330 340 350 360 370 pF1KB0 TRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPEP .: .:.::::::.::..::: :..:.. :::.::::. :.::::::::: :::.::.: NP_001 SRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQIFDCPRLKFSEIPQRLTALLLPPDP 270 280 290 300 310 320 380 390 400 410 420 430 pF1KB0 IIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIET :.:::::::::.::::::::::::::.. :: ::.:::::::.::::..::.:::::::. NP_001 IVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIES 330 340 350 360 370 380 440 450 460 470 480 490 pF1KB0 INQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEA ::::: ::.:::::.:::.:...: :.:: ::::.::::.:::::::::::: :::.::: NP_001 INQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEA 390 400 410 420 430 440 500 510 pF1KB0 VCRYFYSKVQQRRQELEQALGIRNT : :::: :.:::::::::.: .::: NP_001 VSRYFYCKIQQRRQELEQSLVVRNT 450 460 470 >>NP_003069 (OMIM: 601737) SWI/SNF-related matrix-associ (470 aa) initn: 1822 init1: 1619 opt: 2363 Z-score: 1229.8 bits: 237.0 E(85289): 9.2e-62 Smith-Waterman score: 2363; 74.1% identity (88.0% similar) in 475 aa overlap (54-515:3-470) 30 40 50 60 70 pF1KB0 AAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYP-----RPGMLPGSRMTPQGPSMGP :: .: :::: :.:: :: ::: NP_003 MTPGLQHPPTVVQRPGMPSGARMPHQGAPMGP 10 20 30 80 90 100 110 120 130 pF1KB0 PG--YGGNPSVRPGLAQSGMDQSRKR--PAPQQIQ-QVQQQAVQN---RNHNAKKKKMAD :: : :.:.:::::: .::. .::: : : : : : : : : . :...::..:::: NP_003 PGSPYMGSPAVRPGLAPAGMEPARKRAAPPPGQSQAQSQGQPVPTAPARSRSAKRRKMAD 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB0 KILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTF :::::::::::::::::::::::::::::::::::.:::::::::.:::::::..::::: NP_003 KILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTF 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB0 NPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYG :::: ::::..:..:::::::::.::.: .::::::::::::::::::::::: NP_003 NPAKPDAEDSDGSIASWELRVEGKLLDDP-------SKQKRKFSSFFKSLVIELDKDLYG 160 170 180 190 200 260 270 280 290 300 310 pF1KB0 PDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQ ::::::::::: :::::::::::::::..::::.::::::::::::::::::::::.::: NP_003 PDNHLVEWHRTPTTQETDGFQVKRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQ 210 220 230 240 250 260 320 330 340 350 360 370 pF1KB0 TRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPEP .: .:.::::::.::..::: :..:.. :::.::::. :.::::::::: :::.::.: NP_003 SRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQIFDCPRLKFSEIPQRLTALLLPPDP 270 280 290 300 310 320 380 390 400 410 420 430 pF1KB0 IIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIET :.:::::::::.::::::::::::::.. :: ::.:::::::.::::..::.:::::::. NP_003 IVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIES 330 340 350 360 370 380 440 450 460 470 480 490 pF1KB0 INQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEA ::::: ::.:::::.:::.:...: :.:: ::::.::::.:::::::::::: :::.::: NP_003 INQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEA 390 400 410 420 430 440 500 510 pF1KB0 VCRYFYSKVQQRRQELEQALGIRNT : :::: :.:::::::::.: .::: NP_003 VSRYFYCKIQQRRQELEQSLVVRNT 450 460 470 >>NP_001003801 (OMIM: 601737) SWI/SNF-related matrix-ass (483 aa) initn: 1816 init1: 1619 opt: 2356 Z-score: 1226.1 bits: 236.4 E(85289): 1.5e-61 Smith-Waterman score: 2356; 75.2% identity (89.2% similar) in 464 aa overlap (60-515:27-483) 30 40 50 60 70 80 pF1KB0 PGGTPGPPVRMGPAPGQGLYRSPMPGAAYPRPGMLPGSRMTPQGPSMGPPG--YGGNPSV :::: :.:: :: ::::: : :.:.: NP_001 MAADEVAGGARKATKSKLFEFLVHGVRPGMPSGARMPHQGAPMGPPGSPYMGSPAV 10 20 30 40 50 90 100 110 120 130 140 pF1KB0 RPGLAQSGMDQSRKR--PAPQQIQ-QVQQQAVQN---RNHNAKKKKMADKILPQRIRELV ::::: .::. .::: : : : : : : : : . :...::..::::::::::::::: NP_001 RPGLAPAGMEPARKRAAPPPGQSQAQSQGQPVPTAPARSRSAKRRKMADKILPQRIRELV 60 70 80 90 100 110 150 160 170 180 190 200 pF1KB0 PESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGE ::::::::::::::::::::::::.:::::::::.:::::::..::::::::: ::::.. NP_001 PESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSD 120 130 140 150 160 170 210 220 230 240 250 260 pF1KB0 GTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRT :..:::::::::.::.: .:::::::::::::::::::::::::::::::::: NP_001 GSIASWELRVEGKLLDDP-------SKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRT 180 190 200 210 220 270 280 290 300 310 320 pF1KB0 ATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQTRPVIIQALWQ :::::::::::::::..::::.::::::::::::::::::::::.:::.: .:.::::: NP_001 PTTQETDGFQVKRPGDLSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQ 230 240 250 260 270 280 330 340 350 360 370 380 pF1KB0 YIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPEPIIINHVISVDP :.::..::: :..:.. :::.::::. :.::::::::: :::.::.::.::::::::: NP_001 YVKTNRLQDSHDKEYINGDKYFQQIFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDP 290 300 310 320 330 340 390 400 410 420 430 440 pF1KB0 NDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFM .::::::::::::::.. :: ::.:::::::.::::..::.:::::::.::::: ::.:: NP_001 SDQKKTACYDIDVEVEEPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFM 350 360 370 380 390 400 450 460 470 480 490 500 pF1KB0 LSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQ :::.:::.:...: :.:: ::::.::::.:::::::::::: :::.:::: :::: :.:: NP_001 LSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQ 410 420 430 440 450 460 510 pF1KB0 RRQELEQALGIRNT :::::::.: .::: NP_001 RRQELEQSLVVRNT 470 480 >>NP_001091896 (OMIM: 601736) SWI/SNF-related matrix-ass (531 aa) initn: 2159 init1: 1539 opt: 2164 Z-score: 1127.7 bits: 218.3 E(85289): 4.5e-56 Smith-Waterman score: 2208; 63.6% identity (80.1% similar) in 544 aa overlap (1-515:1-531) 10 20 30 40 50 pF1KB0 MAARA--GFQ--SVAPSGGAGASGGAGAAAALGPGGTPGPPVRM-GPA-----PGQGLYR :..:. :: ..:.::: :.. .. ::: ::: .: ::: :: . .: NP_001 MSGRGAGGFPLPPLSPGGGAVAAALGAPPPPAGPGMLPGPALRGPGPAGGVGGPGAAAFR 10 20 30 40 50 60 60 70 80 90 100 pF1KB0 SPM----PGAAYPRPGMLPGSRMTPQGPSMGPPG---YGGNPSVRPGLAQSGMDQSRKRP :: :.: : :::: ::.:: : ..:::. .:. .:::. . :: ::: NP_001 -PMGPAGPAAQYQRPGMSPGNRMPMAGLQVGPPAGSPFGAAAPLRPGMPPTMMDPFRKR- 70 80 90 100 110 110 120 130 140 150 160 pF1KB0 APQQIQQVQQQAVQNRNHNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMR . :.: .: .. :..:::::.::::::::::::::::::::::::::::: : NP_001 --LLVPQAQPPMPAQR-RGLKRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQTIAR 120 130 140 150 160 170 170 180 190 200 210 pF1KB0 KRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGEGT------------VASWELRV ::..::::.:.:. :::::::.:::::.:.:... :. :: :::::::: NP_001 KRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEG-DSAGTAGTPGGTPAGDKVASWELRV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB0 EGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTATTQETDGFQ ::.::. : .:::::::::::::::::::.::::::::::::: ::::::::: NP_001 EGKLLD-------DPSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMPTTQETDGFQ 240 250 260 270 280 280 290 300 310 320 330 pF1KB0 VKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDP ::::::.::.::.:::::.::::.:::::::::::.::::: .:.:::: ::: ..::: NP_001 VKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDG 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB0 HEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPEPIIINHVISVDPNDQKKTACYD ::::.. :..:..::: :..:::::..: .::. :.::.::::::::::::::::::: NP_001 HEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHVISVDPNDQKKTACYD 350 360 370 380 390 400 400 410 420 430 440 450 pF1KB0 IDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGF ::::::: ::.::..:: ::..:::::.:: :::::::.::::::::.:::::. ::: : NP_001 IDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTDPQDF 410 420 430 440 450 460 460 470 480 490 500 510 pF1KB0 INDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALG :..::.:: :::: .:::.::::::::: :: :::::::: :....:::::::::::.:: NP_001 IQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLG 470 480 490 500 510 520 pF1KB0 IRNT :: : NP_001 IRLT 530 >>XP_011514823 (OMIM: 601737) PREDICTED: SWI/SNF-related (381 aa) initn: 1619 init1: 1619 opt: 2127 Z-score: 1110.6 bits: 214.7 E(85289): 4e-55 Smith-Waterman score: 2127; 79.6% identity (93.3% similar) in 388 aa overlap (128-515:1-381) 100 110 120 130 140 150 pF1KB0 QSRKRPAPQQIQQVQQQAVQNRNHNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKL :::::::::::::::::::::::::::::: XP_011 MADKILPQRIRELVPESQAYMDLLAFERKL 10 20 30 160 170 180 190 200 210 pF1KB0 DQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGEGTVASWELRVEGRLLE ::::::::.:::::::::.:::::::..::::::::: ::::..:..:::::::::.::. XP_011 DQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDAEDSDGSIASWELRVEGKLLD 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB0 DSALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPGD : .:::::::::::::::::::::::::::::::::: ::::::::::::::: XP_011 -------DPSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGD 100 110 120 130 140 280 290 300 310 320 330 pF1KB0 VNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFV ..::::.::::::::::::::::::::::.:::.: .:.::::::.::..::: :..:.. XP_011 LSVRCTLLLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYI 150 160 170 180 190 200 340 350 360 370 380 390 pF1KB0 ICDKYLQQIFESQRMKFSEIPQRLHALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVD :::.::::. :.::::::::: :::.::.::.:::::::::.::::::::::::::. XP_011 NGDKYFQQIFDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDIDVEVE 210 220 230 240 250 260 400 410 420 430 440 450 pF1KB0 DTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQ . :: ::.:::::::.::::..::.:::::::.::::: ::.:::::.:::.:...: :. XP_011 EPLKGQMSSFLLSTANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLR 270 280 290 300 310 320 460 470 480 490 500 510 pF1KB0 SQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT :: ::::.::::.:::::::::::: :::.:::: :::: :.:::::::::.: .::: XP_011 SQSRDLKVMTDVAGNPEEERRAEFYHQPWSQEAVSRYFYCKIQQRRQELEQSLVVRNT 330 340 350 360 370 380 >>NP_001317369 (OMIM: 601736) SWI/SNF-related matrix-ass (483 aa) initn: 2141 init1: 1539 opt: 2110 Z-score: 1100.6 bits: 213.2 E(85289): 1.4e-54 Smith-Waterman score: 2110; 67.4% identity (83.4% similar) in 476 aa overlap (55-515:20-483) 30 40 50 60 70 80 pF1KB0 AAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPRPGMLPGSRMTPQGPSMGPPG---Y :: :::: ::.:: : ..:::. . NP_001 MGRRVGVEVTPRWAPQKCQGARPQRPGMSPGNRMPMAGLQVGPPAGSPF 10 20 30 40 90 100 110 120 130 140 pF1KB0 GGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRNHNAKKKKMADKILPQRIRELV :. .:::. . :: ::: . :.: .: .. :..:::::.::::::::: NP_001 GAAAPLRPGMPPTMMDPFRKR---LLVPQAQPPMPAQR-RGLKRRKMADKVLPQRIRELV 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB0 PESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGE :::::::::::::::::::: :::..::::.:.:. :::::::.:::::.:.:... :. NP_001 PESQAYMDLLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEG-DSA 110 120 130 140 150 160 210 220 230 240 pF1KB0 GT------------VASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLY :: ::::::::::.::.: .:::::::::::::::::::.:: NP_001 GTAGTPGGTPAGDKVASWELRVEGKLLDDP-------SKQKRKFSSFFKSLVIELDKELY 170 180 190 200 210 250 260 270 280 290 300 pF1KB0 GPDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHT ::::::::::: :::::::::::::::.::.::.:::::.::::.:::::::::::.:: NP_001 GPDNHLVEWHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHT 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB0 QTRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPE ::: .:.:::: ::: ..::: ::::.. :..:..::: :..:::::..: .::. :. NP_001 QTRAAIMQALWLYIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPD 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB0 PIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIE ::.:::::::::::::::::::::::::: ::.::..:: ::..:::::.:: ::::::: NP_001 PIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIE 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB0 TINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQE .::::::::.:::::. ::: ::..::.:: :::: .:::.::::::::: :: :::::: NP_001 SINQLKTQRDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQE 400 410 420 430 440 450 490 500 510 pF1KB0 AVCRYFYSKVQQRRQELEQALGIRNT :: :....:::::::::::.:::: : NP_001 AVGRHIFAKVQQRRQELEQVLGIRLT 460 470 480 >>NP_001317368 (OMIM: 601736) SWI/SNF-related matrix-ass (456 aa) initn: 2109 init1: 1539 opt: 2078 Z-score: 1084.6 bits: 210.1 E(85289): 1.1e-53 Smith-Waterman score: 2078; 67.5% identity (83.8% similar) in 468 aa overlap (63-515:1-456) 40 50 60 70 80 pF1KB0 TPGPPVRMGPAPGQGLYRSPMPGAAYPRPGMLPGSRMTPQGPSMGPPG---YGGNPSVRP : ::.:: : ..:::. .:. .:: NP_001 MSPGNRMPMAGLQVGPPAGSPFGAAAPLRP 10 20 30 90 100 110 120 130 140 pF1KB0 GLAQSGMDQSRKRPAPQQIQQVQQQAVQNRNHNAKKKKMADKILPQRIRELVPESQAYMD :. . :: ::: . :.: .: .. :..:::::.::::::::::::::::: NP_001 GMPPTMMDPFRKR---LLVPQAQPPMPAQR-RGLKRRKMADKVLPQRIRELVPESQAYMD 40 50 60 70 80 150 160 170 180 190 200 pF1KB0 LLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGEGT------ :::::::::::: :::..::::.:.:. :::::::.:::::.:.:... :. :: NP_001 LLAFERKLDQTIARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEG-DSAGTAGTPGG 90 100 110 120 130 140 210 220 230 240 250 pF1KB0 ------VASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVE ::::::::::.::. : .:::::::::::::::::::.:::::::::: NP_001 TPAGDKVASWELRVEGKLLD-------DPSKQKRKFSSFFKSLVIELDKELYGPDNHLVE 150 160 170 180 190 260 270 280 290 300 310 pF1KB0 WHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQTRPVIIQ ::: :::::::::::::::.::.::.:::::.::::.:::::::::::.::::: .:.: NP_001 WHRMPTTQETDGFQVKRPGDLNVKCTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQ 200 210 220 230 240 250 320 330 340 350 360 370 pF1KB0 ALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPEPIIINHVI ::: ::: ..::: ::::.. :..:..::: :..:::::..: .::. :.::.::::: NP_001 ALWLYIKHNQLQDGHEREYINCNRYFRQIFSCGRLRFSEIPMKLAGLLQHPDPIVINHVI 260 270 280 290 300 310 380 390 400 410 420 430 pF1KB0 SVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQ ::::::::::::::::::::: ::.::..:: ::..:::::.:: :::::::.::::::: NP_001 SVDPNDQKKTACYDIDVEVDDPLKAQMSNFLASTTNQQEIASLDVKIHETIESINQLKTQ 320 330 340 350 360 370 440 450 460 470 480 490 pF1KB0 REFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYS :.:::::. ::: ::..::.:: :::: .:::.::::::::: :: :::::::: :.... NP_001 RDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEERRAAFYHQPWAQEAVGRHIFA 380 390 400 410 420 430 500 510 pF1KB0 KVQQRRQELEQALGIRNT :::::::::::.:::: : NP_001 KVQQRRQELEQVLGIRLT 440 450 >>XP_005269164 (OMIM: 601735) PREDICTED: SWI/SNF-related (474 aa) initn: 3203 init1: 2001 opt: 2029 Z-score: 1059.4 bits: 205.5 E(85289): 2.8e-52 Smith-Waterman score: 3125; 92.0% identity (92.0% similar) in 515 aa overlap (1-515:1-474) 10 20 30 40 50 60 pF1KB0 MAARAGFQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAARAGFQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 PGMLPGSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGMLPGSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 HNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIK--- 130 140 150 160 170 190 200 210 220 230 240 pF1KB0 KLRIFISNTFNPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSL :::::::::::::::::::::: XP_005 --------------------------------------SALSKYDATKQKRKFSSFFKSL 180 190 250 260 270 280 290 300 pF1KB0 VIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPR 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB0 LARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQR 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB0 LHALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATL 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB0 DNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAE 380 390 400 410 420 430 490 500 510 pF1KB0 FYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT ::::::::::::::::::::::::::::::::::: XP_005 FYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT 440 450 460 470 515 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:01:36 2016 done: Sat Nov 5 17:01:37 2016 Total Scan time: 9.600 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]