FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0473, 499 aa 1>>>pF1KB0473 499 - 499 aa - 499 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1782+/-0.000472; mu= 14.8142+/- 0.030 mean_var=341.8772+/-74.966, 0's: 0 Z-trim(119.0): 136 B-trim: 1929 in 1/56 Lambda= 0.069365 statistics sampled from 32374 (32570) to 32374 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.382), width: 16 Scan time: 10.660 The best scores are: opt bits E(85289) XP_016868729 (OMIM: 604819,615583) PREDICTED: poly ( 499) 3216 336.0 1.5e-91 NP_001258029 (OMIM: 604819,615583) poly(U)-binding ( 499) 3216 336.0 1.5e-91 NP_001258026 (OMIM: 604819,615583) poly(U)-binding ( 513) 3216 336.1 1.5e-91 NP_001258025 (OMIM: 604819,615583) poly(U)-binding ( 541) 3216 336.1 1.5e-91 NP_055096 (OMIM: 604819,615583) poly(U)-binding-sp ( 542) 3216 336.1 1.5e-91 XP_016868725 (OMIM: 604819,615583) PREDICTED: poly ( 579) 3216 336.1 1.6e-91 XP_011515232 (OMIM: 604819,615583) PREDICTED: poly ( 579) 3216 336.1 1.6e-91 NP_001129505 (OMIM: 604819,615583) poly(U)-binding ( 516) 2872 301.6 3.5e-81 XP_016868728 (OMIM: 604819,615583) PREDICTED: poly ( 516) 2872 301.6 3.5e-81 NP_001258028 (OMIM: 604819,615583) poly(U)-binding ( 530) 2872 301.7 3.5e-81 NP_001258027 (OMIM: 604819,615583) poly(U)-binding ( 558) 2872 301.7 3.6e-81 NP_510965 (OMIM: 604819,615583) poly(U)-binding-sp ( 559) 2872 301.7 3.6e-81 XP_016868724 (OMIM: 604819,615583) PREDICTED: poly ( 584) 2872 301.7 3.7e-81 XP_016868726 (OMIM: 604819,615583) PREDICTED: poly ( 596) 2872 301.7 3.7e-81 XP_011515231 (OMIM: 604819,615583) PREDICTED: poly ( 596) 2872 301.7 3.7e-81 XP_016868723 (OMIM: 604819,615583) PREDICTED: poly ( 596) 2872 301.7 3.7e-81 XP_016868727 (OMIM: 604819,615583) PREDICTED: poly ( 596) 2872 301.7 3.7e-81 NP_001020259 (OMIM: 612679) CUGBP Elav-like family ( 484) 288 43.0 0.0023 XP_011531379 (OMIM: 603518,604454) PREDICTED: nucl ( 385) 282 42.2 0.0032 NP_071505 (OMIM: 603518,604454) nucleolysin TIA-1 ( 386) 282 42.2 0.0032 NP_620412 (OMIM: 607897) RNA-binding protein Musas ( 328) 278 41.7 0.0039 XP_016883636 (OMIM: 604739) PREDICTED: RNA-binding ( 341) 278 41.7 0.0039 XP_016883635 (OMIM: 604739) PREDICTED: RNA-binding ( 341) 278 41.7 0.0039 XP_016883632 (OMIM: 604739) PREDICTED: RNA-binding ( 367) 278 41.8 0.0041 XP_016883634 (OMIM: 604739) PREDICTED: RNA-binding ( 367) 278 41.8 0.0041 XP_016883630 (OMIM: 604739) PREDICTED: RNA-binding ( 367) 278 41.8 0.0041 XP_016883633 (OMIM: 604739) PREDICTED: RNA-binding ( 367) 278 41.8 0.0041 XP_016883631 (OMIM: 604739) PREDICTED: RNA-binding ( 367) 278 41.8 0.0041 NP_001310352 (OMIM: 604739) RNA-binding protein 39 ( 373) 278 41.8 0.0041 XP_011527413 (OMIM: 604739) PREDICTED: RNA-binding ( 373) 278 41.8 0.0041 XP_006723954 (OMIM: 604739) PREDICTED: RNA-binding ( 373) 278 41.8 0.0041 XP_006723953 (OMIM: 604739) PREDICTED: RNA-binding ( 373) 278 41.8 0.0041 XP_016883629 (OMIM: 604739) PREDICTED: RNA-binding ( 373) 278 41.8 0.0041 XP_016883628 (OMIM: 604739) PREDICTED: RNA-binding ( 373) 278 41.8 0.0041 XP_016883627 (OMIM: 604739) PREDICTED: RNA-binding ( 476) 278 42.0 0.0046 NP_001310351 (OMIM: 604739) RNA-binding protein 39 ( 498) 278 42.0 0.0048 NP_001229529 (OMIM: 604739) RNA-binding protein 39 ( 502) 278 42.0 0.0048 NP_001229528 (OMIM: 604739) RNA-binding protein 39 ( 508) 278 42.0 0.0048 NP_004893 (OMIM: 604739) RNA-binding protein 39 is ( 524) 278 42.1 0.0049 NP_001310353 (OMIM: 604739) RNA-binding protein 39 ( 529) 278 42.1 0.0049 NP_909122 (OMIM: 604739) RNA-binding protein 39 is ( 530) 278 42.1 0.0049 XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 267 40.7 0.0085 XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 267 40.7 0.0085 >>XP_016868729 (OMIM: 604819,615583) PREDICTED: poly(U)- (499 aa) initn: 3216 init1: 3216 opt: 3216 Z-score: 1764.7 bits: 336.0 E(85289): 1.5e-91 Smith-Waterman score: 3216; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:1-499) 10 20 30 40 50 60 pF1KB0 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR 430 440 450 460 470 480 490 pF1KB0 KVVAEVYDQERFDNSDLSA ::::::::::::::::::: XP_016 KVVAEVYDQERFDNSDLSA 490 >>NP_001258029 (OMIM: 604819,615583) poly(U)-binding-spl (499 aa) initn: 3216 init1: 3216 opt: 3216 Z-score: 1764.7 bits: 336.0 E(85289): 1.5e-91 Smith-Waterman score: 3216; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:1-499) 10 20 30 40 50 60 pF1KB0 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR 430 440 450 460 470 480 490 pF1KB0 KVVAEVYDQERFDNSDLSA ::::::::::::::::::: NP_001 KVVAEVYDQERFDNSDLSA 490 >>NP_001258026 (OMIM: 604819,615583) poly(U)-binding-spl (513 aa) initn: 3216 init1: 3216 opt: 3216 Z-score: 1764.6 bits: 336.1 E(85289): 1.5e-91 Smith-Waterman score: 3216; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:15-513) 10 20 30 40 pF1KB0 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIA :::::::::::::::::::::::::::::::::::::::::::::: NP_001 MATATIALGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB0 HQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVT 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB0 MKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFN 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB0 RIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSS 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB0 MNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB0 TLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILAS 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB0 PPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVL 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB0 RNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETH 430 440 450 460 470 480 470 480 490 pF1KB0 KAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA ::::::::::::::::::::::::::::::::: NP_001 KAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 490 500 510 >>NP_001258025 (OMIM: 604819,615583) poly(U)-binding-spl (541 aa) initn: 3216 init1: 3216 opt: 3216 Z-score: 1764.4 bits: 336.1 E(85289): 1.5e-91 Smith-Waterman score: 3216; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:43-541) 10 20 30 pF1KB0 MENGQSTAAKLGLPPLTPEQQEALQKAKKY :::::::::::::::::::::::::::::: NP_001 QGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKY 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB0 AMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFA 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB0 PFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQ 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB0 AQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB0 FIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAAT 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB0 AKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPI 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB0 PVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHM 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB0 VMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAE 440 450 460 470 480 490 460 470 480 490 pF1KB0 IIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 500 510 520 530 540 >>NP_055096 (OMIM: 604819,615583) poly(U)-binding-splici (542 aa) initn: 3216 init1: 3216 opt: 3216 Z-score: 1764.4 bits: 336.1 E(85289): 1.5e-91 Smith-Waterman score: 3216; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:44-542) 10 20 30 pF1KB0 MENGQSTAAKLGLPPLTPEQQEALQKAKKY :::::::::::::::::::::::::::::: NP_055 QGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKY 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB0 AMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFA 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB0 PFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQ 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB0 AQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB0 FIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAAT 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB0 AKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPI 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB0 PVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHM 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB0 VMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAE 440 450 460 470 480 490 460 470 480 490 pF1KB0 IIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA ::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 500 510 520 530 540 >>XP_016868725 (OMIM: 604819,615583) PREDICTED: poly(U)- (579 aa) initn: 3216 init1: 3216 opt: 3216 Z-score: 1764.1 bits: 336.1 E(85289): 1.6e-91 Smith-Waterman score: 3216; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:81-579) 10 20 30 pF1KB0 MENGQSTAAKLGLPPLTPEQQEALQKAKKY :::::::::::::::::::::::::::::: XP_016 QGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKY 60 70 80 90 100 110 40 50 60 70 80 90 pF1KB0 AMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFA 120 130 140 150 160 170 100 110 120 130 140 150 pF1KB0 PFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQ 180 190 200 210 220 230 160 170 180 190 200 210 pF1KB0 AQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB0 FIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAAT 300 310 320 330 340 350 280 290 300 310 320 330 pF1KB0 AKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPI 360 370 380 390 400 410 340 350 360 370 380 390 pF1KB0 PVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHM 420 430 440 450 460 470 400 410 420 430 440 450 pF1KB0 VMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAE 480 490 500 510 520 530 460 470 480 490 pF1KB0 IIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 540 550 560 570 >>XP_011515232 (OMIM: 604819,615583) PREDICTED: poly(U)- (579 aa) initn: 3216 init1: 3216 opt: 3216 Z-score: 1764.1 bits: 336.1 E(85289): 1.6e-91 Smith-Waterman score: 3216; 100.0% identity (100.0% similar) in 499 aa overlap (1-499:81-579) 10 20 30 pF1KB0 MENGQSTAAKLGLPPLTPEQQEALQKAKKY :::::::::::::::::::::::::::::: XP_011 QGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKY 60 70 80 90 100 110 40 50 60 70 80 90 pF1KB0 AMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFA 120 130 140 150 160 170 100 110 120 130 140 150 pF1KB0 PFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQ 180 190 200 210 220 230 160 170 180 190 200 210 pF1KB0 AQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB0 FIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAAT 300 310 320 330 340 350 280 290 300 310 320 330 pF1KB0 AKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPI 360 370 380 390 400 410 340 350 360 370 380 390 pF1KB0 PVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHM 420 430 440 450 460 470 400 410 420 430 440 450 pF1KB0 VMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAE 480 490 500 510 520 530 460 470 480 490 pF1KB0 IIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 540 550 560 570 >>NP_001129505 (OMIM: 604819,615583) poly(U)-binding-spl (516 aa) initn: 2867 init1: 2867 opt: 2872 Z-score: 1578.5 bits: 301.6 E(85289): 3.5e-81 Smith-Waterman score: 3172; 96.7% identity (96.7% similar) in 516 aa overlap (1-499:1-516) 10 20 30 40 50 pF1KB0 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAA- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAV 10 20 30 40 50 60 60 70 80 90 100 pF1KB0 ----------------QRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWD :::::::::::::::::::::::::::::::::::::::::::: NP_001 TMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWD 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB0 SVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEAR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB0 AFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDA 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB0 VSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAA 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB0 VLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPI 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB0 LASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTV 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB0 MVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIAS 430 440 450 460 470 480 470 480 490 pF1KB0 ETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA :::::::::::::::::::::::::::::::::::: NP_001 ETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 490 500 510 >>XP_016868728 (OMIM: 604819,615583) PREDICTED: poly(U)- (516 aa) initn: 2867 init1: 2867 opt: 2872 Z-score: 1578.5 bits: 301.6 E(85289): 3.5e-81 Smith-Waterman score: 3172; 96.7% identity (96.7% similar) in 516 aa overlap (1-499:1-516) 10 20 30 40 50 pF1KB0 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAA- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAV 10 20 30 40 50 60 60 70 80 90 100 pF1KB0 ----------------QRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWD :::::::::::::::::::::::::::::::::::::::::::: XP_016 TMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWD 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB0 SVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEAR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB0 AFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDA 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB0 VSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAA 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB0 VLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPI 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB0 LASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTV 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB0 MVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIAS 430 440 450 460 470 480 470 480 490 pF1KB0 ETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA :::::::::::::::::::::::::::::::::::: XP_016 ETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 490 500 510 >>NP_001258028 (OMIM: 604819,615583) poly(U)-binding-spl (530 aa) initn: 2867 init1: 2867 opt: 2872 Z-score: 1578.4 bits: 301.7 E(85289): 3.5e-81 Smith-Waterman score: 3172; 96.7% identity (96.7% similar) in 516 aa overlap (1-499:15-530) 10 20 30 40 pF1KB0 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIA :::::::::::::::::::::::::::::::::::::::::::::: NP_001 MATATIALGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIA 10 20 30 40 50 60 50 60 70 80 pF1KB0 HQQQQLTNLQMAA-----------------QRQRALAIMCRVYVGSIYYELGEDTIRQAF ::::::::::::: :::::::::::::::::::::::::::::: NP_001 HQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAF 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB0 APFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIG 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB0 QAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGY 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB0 GFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAA 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB0 TAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPP 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB0 IPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARH 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB0 MVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDA 430 440 450 460 470 480 450 460 470 480 490 pF1KB0 EIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 490 500 510 520 530 499 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:02:57 2016 done: Sat Nov 5 17:02:59 2016 Total Scan time: 10.660 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]