FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0477, 518 aa 1>>>pF1KB0477 518 - 518 aa - 518 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3057+/-0.000809; mu= 13.6805+/- 0.049 mean_var=82.5650+/-16.188, 0's: 0 Z-trim(108.5): 18 B-trim: 0 in 0/52 Lambda= 0.141149 statistics sampled from 10243 (10251) to 10243 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.315), width: 16 Scan time: 2.530 The best scores are: opt bits E(32554) CCDS33017.1 SARS2 gene_id:54938|Hs108|chr19 ( 518) 3480 718.4 4.9e-207 CCDS54265.1 SARS2 gene_id:54938|Hs108|chr19 ( 520) 3275 676.6 1.8e-194 CCDS795.1 SARS gene_id:6301|Hs108|chr1 ( 514) 590 129.9 7e-30 CCDS81356.1 SARS gene_id:6301|Hs108|chr1 ( 536) 497 110.9 3.6e-24 >>CCDS33017.1 SARS2 gene_id:54938|Hs108|chr19 (518 aa) initn: 3480 init1: 3480 opt: 3480 Z-score: 3830.4 bits: 718.4 E(32554): 4.9e-207 Smith-Waterman score: 3480; 100.0% identity (100.0% similar) in 518 aa overlap (1-518:1-518) 10 20 30 40 50 60 pF1KB0 MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 ERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 ERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 LANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 GDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 GLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNLAGTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNLAGTA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 EVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 SASNCTDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQKDGSVLVPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SASNCTDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQKDGSVLVPPA 430 440 450 460 470 480 490 500 510 pF1KB0 LQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS :::::::::::::::::::::::::::::::::::::: CCDS33 LQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS 490 500 510 >>CCDS54265.1 SARS2 gene_id:54938|Hs108|chr19 (520 aa) initn: 3300 init1: 2452 opt: 3275 Z-score: 3604.8 bits: 676.6 E(32554): 1.8e-194 Smith-Waterman score: 3275; 95.4% identity (96.2% similar) in 521 aa overlap (1-518:1-520) 10 20 30 40 50 60 pF1KB0 MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 ERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRAL 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 LANQDSGEVQQ---DPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPD ::::::::::: :: .. . . : :::::::::::::::::::::: CCDS54 LANQDSGEVQQVRLDPGAGSIFGPTFLPFPGQLSLLV-EAQLEEQFYLQALKLPNQTHPD 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 VPVGDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VPVGDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGAL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 LQHGLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LQHGLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNLA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 GTAEVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 GTAEVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVT 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB0 GPGLEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 GPGLEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFG 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB0 EVTSASNCTDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQKDGSVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EVTSASNCTDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQKDGSVLV 420 430 440 450 460 470 480 490 500 510 pF1KB0 PPALQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS ::::::::::::::::::::::::::::::::::::::::: CCDS54 PPALQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS 480 490 500 510 520 >>CCDS795.1 SARS gene_id:6301|Hs108|chr1 (514 aa) initn: 433 init1: 287 opt: 590 Z-score: 649.9 bits: 129.9 E(32554): 7e-30 Smith-Waterman score: 596; 29.5% identity (66.4% similar) in 342 aa overlap (158-485:123-460) 130 140 150 160 170 180 pF1KB0 EVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPVGDESQA- .:: . . . .. : ::.::.... .. CCDS79 DALANLKVSQIKKVRLLIDEAILKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDVD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB0 -RVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQHGLVNF .: .. :: : . .:... .: .. .. . :.: :.:.:.:. ..:...:... CCDS79 NKVERIWGDCTVR--KKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQY 160 170 180 190 200 210 250 260 270 280 290 pF1KB0 TFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNI--------DPARFKDLNLA .. : ::. :. .: ..: :.. .. . . ..:.. : . . : CCDS79 ALRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDE-ELYKVIGKGSEKSDDNSYDEKYLI 220 230 240 250 260 300 310 320 330 340 350 pF1KB0 GTAEVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNT-GQEPRGLYRVHHFTKVEMFGV .:.: .:. :. . .:::.... :::.: :... :.. ::..:::.: :.:.: CCDS79 ATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVY 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB0 TGPGLEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRF ..: ..: ...::... :. ::. ...... . :. : .:.:.:::.:: : : CCDS79 SSPHDNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAF 330 340 350 360 370 380 420 430 440 450 460 470 pF1KB0 GEVTSASNCTDFQSRRLHIMF-QTEA--GELQFAHTVNATACAVPRLLIALLESNQQKDG :..: :::::.:.:::.: . ::. ...:.: .::: ::. : . :.::. : . : CCDS79 RELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKG 390 400 410 420 430 440 480 490 500 510 pF1KB0 SVLVPPALQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS . :: :. .. CCDS79 -ITVPEKLKEFMPPGLQELIPFVKPAPIEQEPSKKQKKQHEGSKKKAAARDVTLENRLQN 450 460 470 480 490 500 >>CCDS81356.1 SARS gene_id:6301|Hs108|chr1 (536 aa) initn: 433 init1: 287 opt: 497 Z-score: 547.3 bits: 110.9 E(32554): 3.6e-24 Smith-Waterman score: 554; 28.3% identity (62.9% similar) in 364 aa overlap (158-485:123-482) 130 140 150 160 170 180 pF1KB0 EVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPVGDESQA- .:: . . . .. : ::.::.... .. CCDS81 DALANLKVSQIKKVRLLIDEAILKCDAERIKLEAERFENLREIGNLLHPSVPISNDEDVD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB0 -RVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQHGLVNF .: .. :: : . .:... .: .. .. . :.: :.:.:.:. ..:...:... CCDS81 NKVERIWGDCTVR--KKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQY 160 170 180 190 200 210 250 260 270 280 290 pF1KB0 TFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNI--------DPARFKDLNLA .. : ::. :. .: ..: :.. .. . . ..:.. : . . : CCDS81 ALRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDE-ELYKVIGKGSEKSDDNSYDEKYLI 220 230 240 250 260 300 310 320 330 340 350 pF1KB0 GTAEVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNT-GQEPRGLYRVHHFTKVEMFGV .:.: .:. :. . .:::.... :::.: :... :.. ::..:::.: :.:.: CCDS81 ATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVY 270 280 290 300 310 320 360 370 380 390 400 410 pF1KB0 TGPGLEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRF ..: ..: ...::... :. ::. ...... . :. : .:.:.:::.:: : : CCDS81 SSPHDNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAF 330 340 350 360 370 380 420 430 440 450 pF1KB0 GEVTSASNCTDFQSRRLHIMF-QT-------------------EAG-----ELQFAHTVN :..: :::::.:.:::.: . :: ::. ...:.: .: CCDS81 RELVSCSNCTDYQARRLRIRYGQTKKMMDKRKNNLHLSTQNKLEASLFSPKKVEFVHMLN 390 400 410 420 430 440 460 470 480 490 500 510 pF1KB0 ATACAVPRLLIALLESNQQKDGSVLVPPALQSYLGTDRITAPTHVPLQYIGPNQPRKPGL :: ::. : . :.::. : . : . :: :. .. CCDS81 ATMCATTRTICAILENYQTEKG-ITVPEKLKEFMPPGLQELIPFVKPAPIEQEPSKKQKK 450 460 470 480 490 500 pF1KB0 PGQPAVS CCDS81 QHEGSKKKAAARDVTLENRLQNMEVTDA 510 520 530 518 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:04:55 2016 done: Sat Nov 5 17:04:55 2016 Total Scan time: 2.530 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]