Result of FASTA (omim) for
pF1KB0497
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0497, 4427 aa
1>>>pF1KB0497 4427 - 4427 aa - 4427 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2383+/-0.00067; mu= 19.6555+/- 0.042
mean_var=143.0560+/-29.570, 0's: 0 Z-trim(107.6): 165 B-trim: 476 in 2/56
Lambda= 0.107231
statistics sampled from 15457 (15622) to 15457 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.487), E-opt: 0.2 (0.183), width: 16
Scan time: 28.400
The best scores are: opt bits E(85289)
NP_065928 (OMIM: 603333) dynein heavy chain 2, axo (4427) 29334 4553.1 0
XP_011521969 (OMIM: 603333) PREDICTED: dynein heav (4427) 29334 4553.1 0
XP_011521966 (OMIM: 603333) PREDICTED: dynein heav (4509) 26768 4156.1 0
XP_011521965 (OMIM: 603333) PREDICTED: dynein heav (4509) 26768 4156.1 0
XP_011521970 (OMIM: 603333) PREDICTED: dynein heav (3973) 26259 4077.3 0
XP_011521971 (OMIM: 603333) PREDICTED: dynein heav (3841) 25421 3947.7 0
XP_016879707 (OMIM: 603333) PREDICTED: dynein heav (3844) 25102 3898.3 0
XP_016879708 (OMIM: 603333) PREDICTED: dynein heav (3799) 21620 3359.7 0
XP_011521972 (OMIM: 603333) PREDICTED: dynein heav (3551) 20302 3155.8 0
XP_011521968 (OMIM: 603333) PREDICTED: dynein heav (4446) 14378 2239.4 0
NP_775899 (OMIM: 610063) dynein heavy chain 17, ax (4462) 7652 1198.8 0
XP_011523718 (OMIM: 610063) PREDICTED: dynein heav (4466) 7635 1196.2 0
NP_001363 (OMIM: 603330) dynein heavy chain 9, axo (4486) 7579 1187.6 0
XP_016879781 (OMIM: 603330) PREDICTED: dynein heav (4462) 7077 1109.9 0
XP_011522005 (OMIM: 603330) PREDICTED: dynein heav (4501) 7071 1109.0 0
XP_016879782 (OMIM: 603330) PREDICTED: dynein heav (3795) 6945 1089.4 0
NP_001264044 (OMIM: 603339,611884) dynein heavy ch (4516) 6186 972.1 0
XP_016874450 (OMIM: 605884) PREDICTED: dynein heav (4486) 5736 902.4 0
NP_997320 (OMIM: 605884) dynein heavy chain 10, ax (4471) 5571 876.9 0
XP_005253612 (OMIM: 605884) PREDICTED: dynein heav (4589) 5571 876.9 0
XP_016874451 (OMIM: 605884) PREDICTED: dynein heav (3509) 5544 872.7 0
XP_011536321 (OMIM: 605884) PREDICTED: dynein heav (3536) 5544 872.7 0
XP_011509792 (OMIM: 610061) PREDICTED: dynein heav (3949) 5417 853.0 0
XP_011536319 (OMIM: 605884) PREDICTED: dynein heav (4477) 4994 787.6 0
XP_011536317 (OMIM: 605884) PREDICTED: dynein heav (4526) 4994 787.7 0
XP_011536316 (OMIM: 605884) PREDICTED: dynein heav (4536) 4994 787.7 0
XP_016879783 (OMIM: 603330) PREDICTED: dynein heav (3362) 4971 784.0 0
XP_016880750 (OMIM: 610063) PREDICTED: dynein heav (2244) 4746 749.1 2.7e-214
XP_016878915 (OMIM: 603334) PREDICTED: dynein heav (4032) 4076 645.6 6.9e-183
XP_011536318 (OMIM: 605884) PREDICTED: dynein heav (4526) 3930 623.0 4.7e-176
XP_011512621 (OMIM: 603337) PREDICTED: dynein heav (4671) 3759 596.6 4.5e-168
XP_016873781 (OMIM: 603297) PREDICTED: cytoplasmic (4101) 3757 596.3 5e-168
NP_001368 (OMIM: 603297) cytoplasmic dynein 2 heav (4307) 3757 596.3 5.2e-168
NP_001073932 (OMIM: 603297) cytoplasmic dynein 2 h (4314) 3662 581.6 1.4e-163
XP_011509799 (OMIM: 610061) PREDICTED: dynein heav (2148) 3635 577.2 1.5e-162
XP_016873780 (OMIM: 603297) PREDICTED: cytoplasmic (4237) 3573 567.8 1.9e-159
XP_016874449 (OMIM: 605884) PREDICTED: dynein heav (4494) 3497 556.1 6.9e-156
XP_016878919 (OMIM: 603334) PREDICTED: dynein heav (2095) 3450 548.5 5.9e-154
XP_006718966 (OMIM: 603297) PREDICTED: cytoplasmic (4300) 3412 542.9 6.1e-152
XP_011536322 (OMIM: 605884) PREDICTED: dynein heav (2591) 3373 536.7 2.7e-150
XP_016864673 (OMIM: 603335,608644) PREDICTED: dyne (3071) 3323 529.0 6.5e-148
XP_016864672 (OMIM: 603335,608644) PREDICTED: dyne (3238) 3323 529.0 6.8e-148
XP_016864671 (OMIM: 603335,608644) PREDICTED: dyne (3809) 3323 529.1 7.7e-148
XP_016865816 (OMIM: 603337) PREDICTED: dynein heav (2857) 3265 520.0 3.1e-145
XP_016879784 (OMIM: 603330) PREDICTED: dynein heav (2548) 3253 518.1 1e-144
XP_016864677 (OMIM: 603335,608644) PREDICTED: dyne (2653) 3042 485.5 7.1e-135
XP_016864675 (OMIM: 603335,608644) PREDICTED: dyne (2874) 3042 485.5 7.5e-135
XP_016864674 (OMIM: 603335,608644) PREDICTED: dyne (3023) 3042 485.5 7.8e-135
XP_016864668 (OMIM: 603335,608644) PREDICTED: dyne (4295) 3042 485.7 1e-134
XP_016864667 (OMIM: 603335,608644) PREDICTED: dyne (4295) 3042 485.7 1e-134
>>NP_065928 (OMIM: 603333) dynein heavy chain 2, axonema (4427 aa)
initn: 29334 init1: 29334 opt: 29334 Z-score: 24521.5 bits: 4553.1 E(85289): 0
Smith-Waterman score: 29334; 99.9% identity (100.0% similar) in 4427 aa overlap (1-4427:1-4427)
10 20 30 40 50 60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSAFE
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
NP_065 TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB0 VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB0 SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB0 PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB0 NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB0 SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB0 TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB0 YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB0 LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB0 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB0 RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB0 YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB0 LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KB0 LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KB0 RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KB0 YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KB0 VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KB0 TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KB0 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800 2810 2820
pF1KB0 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV
2770 2780 2790 2800 2810 2820
2830 2840 2850 2860 2870 2880
pF1KB0 DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE
2830 2840 2850 2860 2870 2880
2890 2900 2910 2920 2930 2940
pF1KB0 RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG
2890 2900 2910 2920 2930 2940
2950 2960 2970 2980 2990 3000
pF1KB0 TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL
2950 2960 2970 2980 2990 3000
3010 3020 3030 3040 3050 3060
pF1KB0 LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ
3010 3020 3030 3040 3050 3060
3070 3080 3090 3100 3110 3120
pF1KB0 KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP
3070 3080 3090 3100 3110 3120
3130 3140 3150 3160 3170 3180
pF1KB0 AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD
3130 3140 3150 3160 3170 3180
3190 3200 3210 3220 3230 3240
pF1KB0 FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK
3190 3200 3210 3220 3230 3240
3250 3260 3270 3280 3290 3300
pF1KB0 LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL
3250 3260 3270 3280 3290 3300
3310 3320 3330 3340 3350 3360
pF1KB0 EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN
3310 3320 3330 3340 3350 3360
3370 3380 3390 3400 3410 3420
pF1KB0 PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ
3370 3380 3390 3400 3410 3420
3430 3440 3450 3460 3470 3480
pF1KB0 MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN
3430 3440 3450 3460 3470 3480
3490 3500 3510 3520 3530 3540
pF1KB0 FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN
3490 3500 3510 3520 3530 3540
3550 3560 3570 3580 3590 3600
pF1KB0 IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT
3550 3560 3570 3580 3590 3600
3610 3620 3630 3640 3650 3660
pF1KB0 DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID
3610 3620 3630 3640 3650 3660
3670 3680 3690 3700 3710 3720
pF1KB0 YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG
3670 3680 3690 3700 3710 3720
3730 3740 3750 3760 3770 3780
pF1KB0 QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE
3730 3740 3750 3760 3770 3780
3790 3800 3810 3820 3830 3840
pF1KB0 NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI
3790 3800 3810 3820 3830 3840
3850 3860 3870 3880 3890 3900
pF1KB0 LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL
3850 3860 3870 3880 3890 3900
3910 3920 3930 3940 3950 3960
pF1KB0 SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL
3910 3920 3930 3940 3950 3960
3970 3980 3990 4000 4010 4020
pF1KB0 YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL
3970 3980 3990 4000 4010 4020
4030 4040 4050 4060 4070 4080
pF1KB0 LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA
4030 4040 4050 4060 4070 4080
4090 4100 4110 4120 4130 4140
pF1KB0 LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI
4090 4100 4110 4120 4130 4140
4150 4160 4170 4180 4190 4200
pF1KB0 TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM
4150 4160 4170 4180 4190 4200
4210 4220 4230 4240 4250 4260
pF1KB0 QTILFSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLAMR
:::::::::::::::::::::::::::::::.::::::::::::::::::::::.:::::
NP_065 QTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMR
4210 4220 4230 4240 4250 4260
4270 4280 4290 4300 4310 4320
pF1KB0 VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN
4270 4280 4290 4300 4310 4320
4330 4340 4350 4360 4370 4380
pF1KB0 LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS
4330 4340 4350 4360 4370 4380
4390 4400 4410 4420
pF1KB0 CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
:::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
4390 4400 4410 4420
>>XP_011521969 (OMIM: 603333) PREDICTED: dynein heavy ch (4427 aa)
initn: 29334 init1: 29334 opt: 29334 Z-score: 24521.5 bits: 4553.1 E(85289): 0
Smith-Waterman score: 29334; 99.9% identity (100.0% similar) in 4427 aa overlap (1-4427:1-4427)
10 20 30 40 50 60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSAFE
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_011 TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB0 VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB0 SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB0 PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB0 NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB0 SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB0 TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB0 YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB0 LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB0 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB0 RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB0 YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB0 LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KB0 LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KB0 RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KB0 YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KB0 VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KB0 TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KB0 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800 2810 2820
pF1KB0 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV
2770 2780 2790 2800 2810 2820
2830 2840 2850 2860 2870 2880
pF1KB0 DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE
2830 2840 2850 2860 2870 2880
2890 2900 2910 2920 2930 2940
pF1KB0 RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG
2890 2900 2910 2920 2930 2940
2950 2960 2970 2980 2990 3000
pF1KB0 TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL
2950 2960 2970 2980 2990 3000
3010 3020 3030 3040 3050 3060
pF1KB0 LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ
3010 3020 3030 3040 3050 3060
3070 3080 3090 3100 3110 3120
pF1KB0 KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP
3070 3080 3090 3100 3110 3120
3130 3140 3150 3160 3170 3180
pF1KB0 AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD
3130 3140 3150 3160 3170 3180
3190 3200 3210 3220 3230 3240
pF1KB0 FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK
3190 3200 3210 3220 3230 3240
3250 3260 3270 3280 3290 3300
pF1KB0 LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL
3250 3260 3270 3280 3290 3300
3310 3320 3330 3340 3350 3360
pF1KB0 EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN
3310 3320 3330 3340 3350 3360
3370 3380 3390 3400 3410 3420
pF1KB0 PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ
3370 3380 3390 3400 3410 3420
3430 3440 3450 3460 3470 3480
pF1KB0 MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN
3430 3440 3450 3460 3470 3480
3490 3500 3510 3520 3530 3540
pF1KB0 FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN
3490 3500 3510 3520 3530 3540
3550 3560 3570 3580 3590 3600
pF1KB0 IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT
3550 3560 3570 3580 3590 3600
3610 3620 3630 3640 3650 3660
pF1KB0 DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID
3610 3620 3630 3640 3650 3660
3670 3680 3690 3700 3710 3720
pF1KB0 YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG
3670 3680 3690 3700 3710 3720
3730 3740 3750 3760 3770 3780
pF1KB0 QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE
3730 3740 3750 3760 3770 3780
3790 3800 3810 3820 3830 3840
pF1KB0 NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI
3790 3800 3810 3820 3830 3840
3850 3860 3870 3880 3890 3900
pF1KB0 LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL
3850 3860 3870 3880 3890 3900
3910 3920 3930 3940 3950 3960
pF1KB0 SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL
3910 3920 3930 3940 3950 3960
3970 3980 3990 4000 4010 4020
pF1KB0 YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL
3970 3980 3990 4000 4010 4020
4030 4040 4050 4060 4070 4080
pF1KB0 LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA
4030 4040 4050 4060 4070 4080
4090 4100 4110 4120 4130 4140
pF1KB0 LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI
4090 4100 4110 4120 4130 4140
4150 4160 4170 4180 4190 4200
pF1KB0 TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM
4150 4160 4170 4180 4190 4200
4210 4220 4230 4240 4250 4260
pF1KB0 QTILFSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLAMR
:::::::::::::::::::::::::::::::.::::::::::::::::::::::.:::::
XP_011 QTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMR
4210 4220 4230 4240 4250 4260
4270 4280 4290 4300 4310 4320
pF1KB0 VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN
4270 4280 4290 4300 4310 4320
4330 4340 4350 4360 4370 4380
pF1KB0 LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS
4330 4340 4350 4360 4370 4380
4390 4400 4410 4420
pF1KB0 CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
4390 4400 4410 4420
>>XP_011521966 (OMIM: 603333) PREDICTED: dynein heavy ch (4509 aa)
initn: 26768 init1: 26768 opt: 26768 Z-score: 22376.0 bits: 4156.1 E(85289): 0
Smith-Waterman score: 28848; 98.1% identity (98.1% similar) in 4459 aa overlap (51-4427:51-4509)
30 40 50 60 70 80
pF1KB0 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
::::::::::::::::::::::::::::::
XP_011 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB0 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB0 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
150 160 170 180 190 200
210 220 230 240 250 260
pF1KB0 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
210 220 230 240 250 260
270 280 290 300 310 320
pF1KB0 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
270 280 290 300 310 320
330 340 350 360 370 380
pF1KB0 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
330 340 350 360 370 380
390
pF1KB0 RERLTSLFRK--------------------------------------------------
::::::::::
XP_011 RERLTSLFRKMSNEIIRLCCHAISLDRIFEGYVSSSKEDLQGCILCCHAWKDHYVQAVQM
390 400 410 420 430 440
400 410
pF1KB0 --------------------------------VCDCQYHFARWEDGKQGPLPCFFGAQGP
::::::::::::::::::::::::::::
XP_011 HIQFSSRGWVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGKQGPLPCFFGAQGP
450 460 470 480 490 500
420 430 440 450 460 470
pF1KB0 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSA
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSA
510 520 530 540 550 560
480 490 500 510 520 530
pF1KB0 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
570 580 590 600 610 620
540 550 560 570 580 590
pF1KB0 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
630 640 650 660 670 680
600 610 620 630 640 650
pF1KB0 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
690 700 710 720 730 740
660 670 680 690 700 710
pF1KB0 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
750 760 770 780 790 800
720 730 740 750 760 770
pF1KB0 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
810 820 830 840 850 860
780 790 800 810 820 830
pF1KB0 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
870 880 890 900 910 920
840 850 860 870 880 890
pF1KB0 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
930 940 950 960 970 980
900 910 920 930 940 950
pF1KB0 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KB0 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KB0 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110 1120 1130
pF1KB0 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
1170 1180 1190 1200 1210 1220
1140 1150 1160 1170 1180 1190
pF1KB0 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
1230 1240 1250 1260 1270 1280
1200 1210 1220 1230 1240 1250
pF1KB0 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
1290 1300 1310 1320 1330 1340
1260 1270 1280 1290 1300 1310
pF1KB0 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
1350 1360 1370 1380 1390 1400
1320 1330 1340 1350 1360 1370
pF1KB0 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
1410 1420 1430 1440 1450 1460
1380 1390 1400 1410 1420 1430
pF1KB0 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
1470 1480 1490 1500 1510 1520
1440 1450 1460 1470 1480 1490
pF1KB0 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
1530 1540 1550 1560 1570 1580
1500 1510 1520 1530 1540 1550
pF1KB0 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
1590 1600 1610 1620 1630 1640
1560 1570 1580 1590 1600 1610
pF1KB0 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
1650 1660 1670 1680 1690 1700
1620 1630 1640 1650 1660 1670
pF1KB0 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
1710 1720 1730 1740 1750 1760
1680 1690 1700 1710 1720 1730
pF1KB0 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
1770 1780 1790 1800 1810 1820
1740 1750 1760 1770 1780 1790
pF1KB0 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
1830 1840 1850 1860 1870 1880
1800 1810 1820 1830 1840 1850
pF1KB0 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
1890 1900 1910 1920 1930 1940
1860 1870 1880 1890 1900 1910
pF1KB0 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
1950 1960 1970 1980 1990 2000
1920 1930 1940 1950 1960 1970
pF1KB0 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
2010 2020 2030 2040 2050 2060
1980 1990 2000 2010 2020 2030
pF1KB0 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
2070 2080 2090 2100 2110 2120
2040 2050 2060 2070 2080 2090
pF1KB0 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
2130 2140 2150 2160 2170 2180
2100 2110 2120 2130 2140 2150
pF1KB0 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
2190 2200 2210 2220 2230 2240
2160 2170 2180 2190 2200 2210
pF1KB0 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
2250 2260 2270 2280 2290 2300
2220 2230 2240 2250 2260 2270
pF1KB0 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
2310 2320 2330 2340 2350 2360
2280 2290 2300 2310 2320 2330
pF1KB0 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
2370 2380 2390 2400 2410 2420
2340 2350 2360 2370 2380 2390
pF1KB0 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
2430 2440 2450 2460 2470 2480
2400 2410 2420 2430 2440 2450
pF1KB0 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
2490 2500 2510 2520 2530 2540
2460 2470 2480 2490 2500 2510
pF1KB0 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
2550 2560 2570 2580 2590 2600
2520 2530 2540 2550 2560 2570
pF1KB0 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
2610 2620 2630 2640 2650 2660
2580 2590 2600 2610 2620 2630
pF1KB0 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
2670 2680 2690 2700 2710 2720
2640 2650 2660 2670 2680 2690
pF1KB0 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
2730 2740 2750 2760 2770 2780
2700 2710 2720 2730 2740 2750
pF1KB0 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
2790 2800 2810 2820 2830 2840
2760 2770 2780 2790 2800 2810
pF1KB0 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
2850 2860 2870 2880 2890 2900
2820 2830 2840 2850 2860 2870
pF1KB0 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
2910 2920 2930 2940 2950 2960
2880 2890 2900 2910 2920 2930
pF1KB0 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
2970 2980 2990 3000 3010 3020
2940 2950 2960 2970 2980 2990
pF1KB0 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
3030 3040 3050 3060 3070 3080
3000 3010 3020 3030 3040 3050
pF1KB0 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
3090 3100 3110 3120 3130 3140
3060 3070 3080 3090 3100 3110
pF1KB0 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
3150 3160 3170 3180 3190 3200
3120 3130 3140 3150 3160 3170
pF1KB0 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
3210 3220 3230 3240 3250 3260
3180 3190 3200 3210 3220 3230
pF1KB0 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
3270 3280 3290 3300 3310 3320
3240 3250 3260 3270 3280 3290
pF1KB0 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
3330 3340 3350 3360 3370 3380
3300 3310 3320 3330 3340 3350
pF1KB0 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
3390 3400 3410 3420 3430 3440
3360 3370 3380 3390 3400 3410
pF1KB0 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
3450 3460 3470 3480 3490 3500
3420 3430 3440 3450 3460 3470
pF1KB0 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
3510 3520 3530 3540 3550 3560
3480 3490 3500 3510 3520 3530
pF1KB0 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
3570 3580 3590 3600 3610 3620
3540 3550 3560 3570 3580 3590
pF1KB0 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
3630 3640 3650 3660 3670 3680
3600 3610 3620 3630 3640 3650
pF1KB0 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
3690 3700 3710 3720 3730 3740
3660 3670 3680 3690 3700 3710
pF1KB0 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
3750 3760 3770 3780 3790 3800
3720 3730 3740 3750 3760 3770
pF1KB0 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
3810 3820 3830 3840 3850 3860
3780 3790 3800 3810 3820 3830
pF1KB0 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
3870 3880 3890 3900 3910 3920
3840 3850 3860 3870 3880 3890
pF1KB0 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
3930 3940 3950 3960 3970 3980
3900 3910 3920 3930 3940 3950
pF1KB0 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
3990 4000 4010 4020 4030 4040
3960 3970 3980 3990 4000 4010
pF1KB0 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
4050 4060 4070 4080 4090 4100
4020 4030 4040 4050 4060 4070
pF1KB0 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
4110 4120 4130 4140 4150 4160
4080 4090 4100 4110 4120 4130
pF1KB0 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
4170 4180 4190 4200 4210 4220
4140 4150 4160 4170 4180 4190
pF1KB0 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
4230 4240 4250 4260 4270 4280
4200 4210 4220 4230 4240 4250
pF1KB0 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLA
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::.:::
XP_011 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLA
4290 4300 4310 4320 4330 4340
4260 4270 4280 4290 4300 4310
pF1KB0 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
4350 4360 4370 4380 4390 4400
4320 4330 4340 4350 4360 4370
pF1KB0 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
4410 4420 4430 4440 4450 4460
4380 4390 4400 4410 4420
pF1KB0 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
4470 4480 4490 4500
>--
initn: 312 init1: 312 opt: 312 Z-score: 256.7 bits: 63.3 E(85289): 1.5e-07
Smith-Waterman score: 312; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)
10 20 30 40 50 60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
XP_011 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
70 80 90 100 110 120
>>XP_011521965 (OMIM: 603333) PREDICTED: dynein heavy ch (4509 aa)
initn: 26768 init1: 26768 opt: 26768 Z-score: 22376.0 bits: 4156.1 E(85289): 0
Smith-Waterman score: 28848; 98.1% identity (98.1% similar) in 4459 aa overlap (51-4427:51-4509)
30 40 50 60 70 80
pF1KB0 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
::::::::::::::::::::::::::::::
XP_011 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB0 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB0 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
150 160 170 180 190 200
210 220 230 240 250 260
pF1KB0 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
210 220 230 240 250 260
270 280 290 300 310 320
pF1KB0 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
270 280 290 300 310 320
330 340 350 360 370 380
pF1KB0 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
330 340 350 360 370 380
390
pF1KB0 RERLTSLFRK--------------------------------------------------
::::::::::
XP_011 RERLTSLFRKMSNEIIRLCCHAISLDRIFEGYVSSSKEDLQGCILCCHAWKDHYVQAVQM
390 400 410 420 430 440
400 410
pF1KB0 --------------------------------VCDCQYHFARWEDGKQGPLPCFFGAQGP
::::::::::::::::::::::::::::
XP_011 HIQFSSRGWVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGKQGPLPCFFGAQGP
450 460 470 480 490 500
420 430 440 450 460 470
pF1KB0 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSA
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSA
510 520 530 540 550 560
480 490 500 510 520 530
pF1KB0 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
570 580 590 600 610 620
540 550 560 570 580 590
pF1KB0 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
630 640 650 660 670 680
600 610 620 630 640 650
pF1KB0 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
690 700 710 720 730 740
660 670 680 690 700 710
pF1KB0 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
750 760 770 780 790 800
720 730 740 750 760 770
pF1KB0 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
810 820 830 840 850 860
780 790 800 810 820 830
pF1KB0 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
870 880 890 900 910 920
840 850 860 870 880 890
pF1KB0 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
930 940 950 960 970 980
900 910 920 930 940 950
pF1KB0 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KB0 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KB0 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110 1120 1130
pF1KB0 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
1170 1180 1190 1200 1210 1220
1140 1150 1160 1170 1180 1190
pF1KB0 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
1230 1240 1250 1260 1270 1280
1200 1210 1220 1230 1240 1250
pF1KB0 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
1290 1300 1310 1320 1330 1340
1260 1270 1280 1290 1300 1310
pF1KB0 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
1350 1360 1370 1380 1390 1400
1320 1330 1340 1350 1360 1370
pF1KB0 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
1410 1420 1430 1440 1450 1460
1380 1390 1400 1410 1420 1430
pF1KB0 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
1470 1480 1490 1500 1510 1520
1440 1450 1460 1470 1480 1490
pF1KB0 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
1530 1540 1550 1560 1570 1580
1500 1510 1520 1530 1540 1550
pF1KB0 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
1590 1600 1610 1620 1630 1640
1560 1570 1580 1590 1600 1610
pF1KB0 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
1650 1660 1670 1680 1690 1700
1620 1630 1640 1650 1660 1670
pF1KB0 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
1710 1720 1730 1740 1750 1760
1680 1690 1700 1710 1720 1730
pF1KB0 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
1770 1780 1790 1800 1810 1820
1740 1750 1760 1770 1780 1790
pF1KB0 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
1830 1840 1850 1860 1870 1880
1800 1810 1820 1830 1840 1850
pF1KB0 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
1890 1900 1910 1920 1930 1940
1860 1870 1880 1890 1900 1910
pF1KB0 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
1950 1960 1970 1980 1990 2000
1920 1930 1940 1950 1960 1970
pF1KB0 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
2010 2020 2030 2040 2050 2060
1980 1990 2000 2010 2020 2030
pF1KB0 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
2070 2080 2090 2100 2110 2120
2040 2050 2060 2070 2080 2090
pF1KB0 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
2130 2140 2150 2160 2170 2180
2100 2110 2120 2130 2140 2150
pF1KB0 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
2190 2200 2210 2220 2230 2240
2160 2170 2180 2190 2200 2210
pF1KB0 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
2250 2260 2270 2280 2290 2300
2220 2230 2240 2250 2260 2270
pF1KB0 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
2310 2320 2330 2340 2350 2360
2280 2290 2300 2310 2320 2330
pF1KB0 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
2370 2380 2390 2400 2410 2420
2340 2350 2360 2370 2380 2390
pF1KB0 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
2430 2440 2450 2460 2470 2480
2400 2410 2420 2430 2440 2450
pF1KB0 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
2490 2500 2510 2520 2530 2540
2460 2470 2480 2490 2500 2510
pF1KB0 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
2550 2560 2570 2580 2590 2600
2520 2530 2540 2550 2560 2570
pF1KB0 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
2610 2620 2630 2640 2650 2660
2580 2590 2600 2610 2620 2630
pF1KB0 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
2670 2680 2690 2700 2710 2720
2640 2650 2660 2670 2680 2690
pF1KB0 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
2730 2740 2750 2760 2770 2780
2700 2710 2720 2730 2740 2750
pF1KB0 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
2790 2800 2810 2820 2830 2840
2760 2770 2780 2790 2800 2810
pF1KB0 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
2850 2860 2870 2880 2890 2900
2820 2830 2840 2850 2860 2870
pF1KB0 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
2910 2920 2930 2940 2950 2960
2880 2890 2900 2910 2920 2930
pF1KB0 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
2970 2980 2990 3000 3010 3020
2940 2950 2960 2970 2980 2990
pF1KB0 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
3030 3040 3050 3060 3070 3080
3000 3010 3020 3030 3040 3050
pF1KB0 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
3090 3100 3110 3120 3130 3140
3060 3070 3080 3090 3100 3110
pF1KB0 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
3150 3160 3170 3180 3190 3200
3120 3130 3140 3150 3160 3170
pF1KB0 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
3210 3220 3230 3240 3250 3260
3180 3190 3200 3210 3220 3230
pF1KB0 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
3270 3280 3290 3300 3310 3320
3240 3250 3260 3270 3280 3290
pF1KB0 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
3330 3340 3350 3360 3370 3380
3300 3310 3320 3330 3340 3350
pF1KB0 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
3390 3400 3410 3420 3430 3440
3360 3370 3380 3390 3400 3410
pF1KB0 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
3450 3460 3470 3480 3490 3500
3420 3430 3440 3450 3460 3470
pF1KB0 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
3510 3520 3530 3540 3550 3560
3480 3490 3500 3510 3520 3530
pF1KB0 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
3570 3580 3590 3600 3610 3620
3540 3550 3560 3570 3580 3590
pF1KB0 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
3630 3640 3650 3660 3670 3680
3600 3610 3620 3630 3640 3650
pF1KB0 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
3690 3700 3710 3720 3730 3740
3660 3670 3680 3690 3700 3710
pF1KB0 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
3750 3760 3770 3780 3790 3800
3720 3730 3740 3750 3760 3770
pF1KB0 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
3810 3820 3830 3840 3850 3860
3780 3790 3800 3810 3820 3830
pF1KB0 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
3870 3880 3890 3900 3910 3920
3840 3850 3860 3870 3880 3890
pF1KB0 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
3930 3940 3950 3960 3970 3980
3900 3910 3920 3930 3940 3950
pF1KB0 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
3990 4000 4010 4020 4030 4040
3960 3970 3980 3990 4000 4010
pF1KB0 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
4050 4060 4070 4080 4090 4100
4020 4030 4040 4050 4060 4070
pF1KB0 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
4110 4120 4130 4140 4150 4160
4080 4090 4100 4110 4120 4130
pF1KB0 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
4170 4180 4190 4200 4210 4220
4140 4150 4160 4170 4180 4190
pF1KB0 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
4230 4240 4250 4260 4270 4280
4200 4210 4220 4230 4240 4250
pF1KB0 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLA
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::.:::
XP_011 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLA
4290 4300 4310 4320 4330 4340
4260 4270 4280 4290 4300 4310
pF1KB0 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
4350 4360 4370 4380 4390 4400
4320 4330 4340 4350 4360 4370
pF1KB0 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
4410 4420 4430 4440 4450 4460
4380 4390 4400 4410 4420
pF1KB0 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
4470 4480 4490 4500
>--
initn: 312 init1: 312 opt: 312 Z-score: 256.7 bits: 63.3 E(85289): 1.5e-07
Smith-Waterman score: 312; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)
10 20 30 40 50 60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
XP_011 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
70 80 90 100 110 120
>>XP_011521970 (OMIM: 603333) PREDICTED: dynein heavy ch (3973 aa)
initn: 26259 init1: 26259 opt: 26259 Z-score: 21951.2 bits: 4077.3 E(85289): 0
Smith-Waterman score: 26259; 99.8% identity (99.9% similar) in 3972 aa overlap (456-4427:2-3973)
430 440 450 460 470 480
pF1KB0 EIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSAFELVRDV
: .::::::: ::::::::::::::::::
XP_011 MDSCRFRAGIKDLEVMTQNLITSAFELVRDV
10 20 30
490 500 510 520 530 540
pF1KB0 PHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPYVAQYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPYVAQYS
40 50 60 70 80 90
550 560 570 580 590 600
pF1KB0 GKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSS
100 110 120 130 140 150
610 620 630 640 650 660
pF1KB0 LDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERA
160 170 180 190 200 210
670 680 690 700 710 720
pF1KB0 EDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAF
220 230 240 250 260 270
730 740 750 760 770 780
pF1KB0 FITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHR
280 290 300 310 320 330
790 800 810 820 830 840
pF1KB0 AAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLL
340 350 360 370 380 390
850 860 870 880 890 900
pF1KB0 ELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTIS
400 410 420 430 440 450
910 920 930 940 950 960
pF1KB0 VFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREI
460 470 480 490 500 510
970 980 990 1000 1010 1020
pF1KB0 WEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLV
520 530 540 550 560 570
1030 1040 1050 1060 1070 1080
pF1KB0 QHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDL
580 590 600 610 620 630
1090 1100 1110 1120 1130 1140
pF1KB0 ANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKF
640 650 660 670 680 690
1150 1160 1170 1180 1190 1200
pF1KB0 KTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRA
700 710 720 730 740 750
1210 1220 1230 1240 1250 1260
pF1KB0 NLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAH
760 770 780 790 800 810
1270 1280 1290 1300 1310 1320
pF1KB0 GLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQR
820 830 840 850 860 870
1330 1340 1350 1360 1370 1380
pF1KB0 EFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPY
880 890 900 910 920 930
1390 1400 1410 1420 1430 1440
pF1KB0 KDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILT
940 950 960 970 980 990
1450 1460 1470 1480 1490 1500
pF1KB0 VQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDT
1000 1010 1020 1030 1040 1050
1510 1520 1530 1540 1550 1560
pF1KB0 LIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDN
1060 1070 1080 1090 1100 1110
1570 1580 1590 1600 1610 1620
pF1KB0 IKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLL
1120 1130 1140 1150 1160 1170
1630 1640 1650 1660 1670 1680
pF1KB0 RNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKN
1180 1190 1200 1210 1220 1230
1690 1700 1710 1720 1730 1740
pF1KB0 QVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRF
1240 1250 1260 1270 1280 1290
1750 1760 1770 1780 1790 1800
pF1KB0 YWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPA
1300 1310 1320 1330 1340 1350
1810 1820 1830 1840 1850 1860
pF1KB0 GTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVL
1360 1370 1380 1390 1400 1410
1870 1880 1890 1900 1910 1920
pF1KB0 SVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRP
1420 1430 1440 1450 1460 1470
1930 1940 1950 1960 1970 1980
pF1KB0 IAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLR
1480 1490 1500 1510 1520 1530
1990 2000 2010 2020 2030 2040
pF1KB0 YAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLR
1540 1550 1560 1570 1580 1590
2050 2060 2070 2080 2090 2100
pF1KB0 ETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLC
1600 1610 1620 1630 1640 1650
2110 2120 2130 2140 2150 2160
pF1KB0 RAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWIL
1660 1670 1680 1690 1700 1710
2170 2180 2190 2200 2210 2220
pF1KB0 FDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMV
1720 1730 1740 1750 1760 1770
2230 2240 2250 2260 2270 2280
pF1KB0 YTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGIT
1780 1790 1800 1810 1820 1830
2290 2300 2310 2320 2330 2340
pF1KB0 SLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIE
1840 1850 1860 1870 1880 1890
2350 2360 2370 2380 2390 2400
pF1KB0 GSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSL
1900 1910 1920 1930 1940 1950
2410 2420 2430 2440 2450 2460
pF1KB0 VANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKR
1960 1970 1980 1990 2000 2010
2470 2480 2490 2500 2510 2520
pF1KB0 TKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREM
2020 2030 2040 2050 2060 2070
2530 2540 2550 2560 2570 2580
pF1KB0 FLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIG
2080 2090 2100 2110 2120 2130
2590 2600 2610 2620 2630 2640
pF1KB0 NVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWI
2140 2150 2160 2170 2180 2190
2650 2660 2670 2680 2690 2700
pF1KB0 HECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYED
2200 2210 2220 2230 2240 2250
2710 2720 2730 2740 2750 2760
pF1KB0 LTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGG
2260 2270 2280 2290 2300 2310
2770 2780 2790 2800 2810 2820
pF1KB0 SGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIA
2320 2330 2340 2350 2360 2370
2830 2840 2850 2860 2870 2880
pF1KB0 DESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNN
2380 2390 2400 2410 2420 2430
2890 2900 2910 2920 2930 2940
pF1KB0 LHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENI
2440 2450 2460 2470 2480 2490
2950 2960 2970 2980 2990 3000
pF1KB0 HRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQAN
2500 2510 2520 2530 2540 2550
3010 3020 3030 3040 3050 3060
pF1KB0 KLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTA
2560 2570 2580 2590 2600 2610
3070 3080 3090 3100 3110 3120
pF1KB0 NSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEI
2620 2630 2640 2650 2660 2670
3130 3140 3150 3160 3170 3180
pF1KB0 VMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDI
2680 2690 2700 2710 2720 2730
3190 3200 3210 3220 3230 3240
pF1KB0 IGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVA
2740 2750 2760 2770 2780 2790
3250 3260 3270 3280 3290 3300
pF1KB0 EKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLG
2800 2810 2820 2830 2840 2850
3310 3320 3330 3340 3350 3360
pF1KB0 YLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVR
2860 2870 2880 2890 2900 2910
3370 3380 3390 3400 3410 3420
pF1KB0 DWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYL
2920 2930 2940 2950 2960 2970
3430 3440 3450 3460 3470 3480
pF1KB0 RILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYI
2980 2990 3000 3010 3020 3030
3490 3500 3510 3520 3530 3540
pF1KB0 TTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGK
3040 3050 3060 3070 3080 3090
3550 3560 3570 3580 3590 3600
pF1KB0 RKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLARE
3100 3110 3120 3130 3140 3150
3610 3620 3630 3640 3650 3660
pF1KB0 AYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDY
3160 3170 3180 3190 3200 3210
3670 3680 3690 3700 3710 3720
pF1KB0 HTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNP
3220 3230 3240 3250 3260 3270
3730 3740 3750 3760 3770 3780
pF1KB0 CSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNE
3280 3290 3300 3310 3320 3330
3790 3800 3810 3820 3830 3840
pF1KB0 MQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGV
3340 3350 3360 3370 3380 3390
3850 3860 3870 3880 3890 3900
pF1KB0 DPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPN
3400 3410 3420 3430 3440 3450
3910 3920 3930 3940 3950 3960
pF1KB0 LDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMS
3460 3470 3480 3490 3500 3510
3970 3980 3990 4000 4010 4020
pF1KB0 EPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYL
3520 3530 3540 3550 3560 3570
4030 4040 4050 4060 4070 4080
pF1KB0 DEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYF
3580 3590 3600 3610 3620 3630
4090 4100 4110 4120 4130 4140
pF1KB0 IPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRA
3640 3650 3660 3670 3680 3690
4150 4160 4170 4180 4190 4200
pF1KB0 GGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILF
3700 3710 3720 3730 3740 3750
4210 4220 4230 4240 4250 4260
pF1KB0 SLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLAMRVEQFE
::::::::::::::::::::::::::.::::::::::::::::::::::.::::::::::
XP_011 SLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQFE
3760 3770 3780 3790 3800 3810
4270 4280 4290 4300 4310 4320
pF1KB0 LWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPP
3820 3830 3840 3850 3860 3870
4330 4340 4350 4360 4370 4380
pF1KB0 KDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYY
3880 3890 3900 3910 3920 3930
4390 4400 4410 4420
pF1KB0 YPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
::::::::::::::::::::::::::::::::::::::::::
XP_011 YPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
3940 3950 3960 3970
>>XP_011521971 (OMIM: 603333) PREDICTED: dynein heavy ch (3841 aa)
initn: 25421 init1: 25421 opt: 25421 Z-score: 21250.8 bits: 3947.7 E(85289): 0
Smith-Waterman score: 25421; 99.9% identity (100.0% similar) in 3841 aa overlap (587-4427:1-3841)
560 570 580 590 600 610
pF1KB0 RIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSSLDKDCIRRLDT
::::::::::::::::::::::::::::::
XP_011 MVQAIDELVRKTFQEWTSSLDKDCIRRLDT
10 20 30
620 630 640 650 660 670
pF1KB0 PLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILRENLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILRENLL
40 50 60 70 80 90
680 690 700 710 720 730
pF1KB0 LVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRIHASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRIHASK
100 110 120 130 140 150
740 750 760 770 780 790
pF1KB0 VQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHRAAVQQKLMNLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHRAAVQQKLMNLH
160 170 180 190 200 210
800 810 820 830 840 850
pF1KB0 QDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGK
220 230 240 250 260 270
860 870 880 890 900 910
pF1KB0 TSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTK
280 290 300 310 320 330
920 930 940 950 960 970
pF1KB0 RKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHR
340 350 360 370 380 390
980 990 1000 1010 1020 1030
pF1KB0 YQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFA
400 410 420 430 440 450
1040 1050 1060 1070 1080 1090
pF1KB0 TLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPIH
460 470 480 490 500 510
1100 1110 1120 1130 1140 1150
pF1KB0 EQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDF
520 530 540 550 560 570
1160 1170 1180 1190 1200 1210
pF1KB0 KKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPP
580 590 600 610 620 630
1220 1230 1240 1250 1260 1270
pF1KB0 SKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAK
640 650 660 670 680 690
1280 1290 1300 1310 1320 1330
pF1KB0 EYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTL
700 710 720 730 740 750
1340 1350 1360 1370 1380 1390
pF1KB0 EQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGT
760 770 780 790 800 810
1400 1410 1420 1430 1440 1450
pF1KB0 EEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENI
820 830 840 850 860 870
1460 1470 1480 1490 1500 1510
pF1KB0 FLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDI
880 890 900 910 920 930
1520 1530 1540 1550 1560 1570
pF1KB0 QKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGG
940 950 960 970 980 990
1580 1590 1600 1610 1620 1630
pF1KB0 PSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFL
1000 1010 1020 1030 1040 1050
1640 1650 1660 1670 1680 1690
pF1KB0 NKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEA
1060 1070 1080 1090 1100 1110
1700 1710 1720 1730 1740 1750
pF1KB0 IRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVI
1120 1130 1140 1150 1160 1170
1760 1770 1780 1790 1800 1810
pF1KB0 RQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDL
1180 1190 1200 1210 1220 1230
1820 1830 1840 1850 1860 1870
pF1KB0 GKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCIL
1240 1250 1260 1270 1280 1290
1880 1890 1900 1910 1920 1930
pF1KB0 SALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLI
1300 1310 1320 1330 1340 1350
1940 1950 1960 1970 1980 1990
pF1KB0 AEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPD
1360 1370 1380 1390 1400 1410
2000 2010 2020 2030 2040 2050
pF1KB0 LTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMG
1420 1430 1440 1450 1460 1470
2060 2070 2080 2090 2100 2110
pF1KB0 LQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVR
1480 1490 1500 1510 1520 1530
2120 2130 2140 2150 2160 2170
pF1KB0 EFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIE
1540 1550 1560 1570 1580 1590
2180 2190 2200 2210 2220 2230
pF1KB0 NMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKP
1600 1610 1620 1630 1640 1650
2240 2250 2260 2270 2280 2290
pF1KB0 YVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALAT
1660 1670 1680 1690 1700 1710
2300 2310 2320 2330 2340 2350
pF1KB0 PENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIEGSFPNKDTVYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIEGSFPNKDTVYE
1720 1730 1740 1750 1760 1770
2360 2370 2380 2390 2400 2410
pF1KB0 YFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVG
1780 1790 1800 1810 1820 1830
2420 2430 2440 2450 2460 2470
pF1KB0 PVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGK
1840 1850 1860 1870 1880 1890
2480 2490 2500 2510 2520 2530
pF1KB0 SMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGG
1900 1910 1920 1930 1940 1950
2540 2550 2560 2570 2580 2590
pF1KB0 GRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDMY
1960 1970 1980 1990 2000 2010
2600 2610 2620 2630 2640 2650
pF1KB0 NTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRL
2020 2030 2040 2050 2060 2070
2660 2670 2680 2690 2700 2710
pF1KB0 VDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYEDLTDLTVLKTVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYEDLTDLTVLKTVM
2080 2090 2100 2110 2120 2130
2720 2730 2740 2750 2760 2770
pF1KB0 ETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLAS
2140 2150 2160 2170 2180 2190
2780 2790 2800 2810 2820 2830
pF1KB0 SICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNI
2200 2210 2220 2230 2240 2250
2840 2850 2860 2870 2880 2890
pF1KB0 LSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCLSPMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCLSPMG
2260 2270 2280 2290 2300 2310
2900 2910 2920 2930 2940 2950
pF1KB0 DPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVTM
2320 2330 2340 2350 2360 2370
2960 2970 2980 2990 3000 3010
pF1KB0 HWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDE
2380 2390 2400 2410 2420 2430
3020 3030 3040 3050 3060 3070
pF1KB0 TREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIK
2440 2450 2460 2470 2480 2490
3080 3090 3100 3110 3120 3130
pF1KB0 CQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGN
2500 2510 2520 2530 2540 2550
3140 3150 3160 3170 3180 3190
pF1KB0 EPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSL
2560 2570 2580 2590 2600 2610
3200 3210 3220 3230 3240 3250
pF1KB0 CMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYD
2620 2630 2640 2650 2660 2670
3260 3270 3280 3290 3300 3310
pF1KB0 EKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAA
2680 2690 2700 2710 2720 2730
3320 3330 3340 3350 3360 3370
pF1KB0 FLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDA
2740 2750 2760 2770 2780 2790
3380 3390 3400 3410 3420 3430
pF1KB0 FSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGY
2800 2810 2820 2830 2840 2850
3440 3450 3460 3470 3480 3490
pF1KB0 PVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSP
2860 2870 2880 2890 2900 2910
3500 3510 3520 3530 3540 3550
pF1KB0 ETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEIL
2920 2930 2940 2950 2960 2970
3560 3570 3580 3590 3600 3610
pF1KB0 RLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASI
2980 2990 3000 3010 3020 3030
3620 3630 3640 3650 3660 3670
pF1KB0 LFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCR
3040 3050 3060 3070 3080 3090
3680 3690 3700 3710 3720 3730
pF1KB0 TLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWD
3100 3110 3120 3130 3140 3150
3740 3750 3760 3770 3780 3790
pF1KB0 NITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLR
3160 3170 3180 3190 3200 3210
3800 3810 3820 3830 3840 3850
pF1KB0 QDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAE
3220 3230 3240 3250 3260 3270
3860 3870 3880 3890 3900 3910
pF1KB0 HMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVE
3280 3290 3300 3310 3320 3330
3920 3930 3940 3950 3960 3970
pF1KB0 DPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPA
3340 3350 3360 3370 3380 3390
3980 3990 4000 4010 4020 4030
pF1KB0 KYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDAL
3400 3410 3420 3430 3440 3450
4040 4050 4060 4070 4080 4090
pF1KB0 KYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYK
3460 3470 3480 3490 3500 3510
4100 4110 4120 4130 4140 4150
pF1KB0 EYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLE
3520 3530 3540 3550 3560 3570
4160 4170 4180 4190 4200 4210
pF1KB0 LAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQG
3580 3590 3600 3610 3620 3630
4220 4230 4240 4250 4260 4270
pF1KB0 LIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLAMRVEQFELWASRARPPVI
:::::::::::::::.::::::::::::::::::::::.:::::::::::::::::::::
XP_011 LIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVI
3640 3650 3660 3670 3680 3690
4280 4290 4300 4310 4320 4330
pF1KB0 FWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYL
3700 3710 3720 3730 3740 3750
4340 4350 4360 4370 4380 4390
pF1KB0 EGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSSDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSSDRA
3760 3770 3780 3790 3800 3810
4400 4410 4420
pF1KB0 SFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
:::::::::::::::::::::::::::::::
XP_011 SFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
3820 3830 3840
>>XP_016879707 (OMIM: 603333) PREDICTED: dynein heavy ch (3844 aa)
initn: 25102 init1: 25102 opt: 25102 Z-score: 20984.1 bits: 3898.3 E(85289): 0
Smith-Waterman score: 25102; 99.9% identity (100.0% similar) in 3793 aa overlap (635-4427:52-3844)
610 620 630 640 650 660
pF1KB0 SLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAER
.:::::::::::::::::::::::::::::
XP_016 FFAGACPLQLNFKAKRQLPFIITLEPHLPWRSLLILFAEIDYWERLLFETPHYVVNVAER
30 40 50 60 70 80
670 680 690 700 710 720
pF1KB0 AEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASA
90 100 110 120 130 140
730 740 750 760 770 780
pF1KB0 FFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREH
150 160 170 180 190 200
790 800 810 820 830 840
pF1KB0 RAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSL
210 220 230 240 250 260
850 860 870 880 890 900
pF1KB0 LELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTI
270 280 290 300 310 320
910 920 930 940 950 960
pF1KB0 SVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYRE
330 340 350 360 370 380
970 980 990 1000 1010 1020
pF1KB0 IWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSL
390 400 410 420 430 440
1030 1040 1050 1060 1070 1080
pF1KB0 VQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHD
450 460 470 480 490 500
1090 1100 1110 1120 1130 1140
pF1KB0 LANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEK
510 520 530 540 550 560
1150 1160 1170 1180 1190 1200
pF1KB0 FKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLR
570 580 590 600 610 620
1210 1220 1230 1240 1250 1260
pF1KB0 ANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTA
630 640 650 660 670 680
1270 1280 1290 1300 1310 1320
pF1KB0 HGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQ
690 700 710 720 730 740
1330 1340 1350 1360 1370 1380
pF1KB0 REFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVP
750 760 770 780 790 800
1390 1400 1410 1420 1430 1440
pF1KB0 YKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMIL
810 820 830 840 850 860
1450 1460 1470 1480 1490 1500
pF1KB0 TVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLD
870 880 890 900 910 920
1510 1520 1530 1540 1550 1560
pF1KB0 TLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFD
930 940 950 960 970 980
1570 1580 1590 1600 1610 1620
pF1KB0 NIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDL
990 1000 1010 1020 1030 1040
1630 1640 1650 1660 1670 1680
pF1KB0 LRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKK
1050 1060 1070 1080 1090 1100
1690 1700 1710 1720 1730 1740
pF1KB0 NQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLR
1110 1120 1130 1140 1150 1160
1750 1760 1770 1780 1790 1800
pF1KB0 FYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGP
1170 1180 1190 1200 1210 1220
1810 1820 1830 1840 1850 1860
pF1KB0 AGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEV
1230 1240 1250 1260 1270 1280
1870 1880 1890 1900 1910 1920
pF1KB0 LSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFR
1290 1300 1310 1320 1330 1340
1930 1940 1950 1960 1970 1980
pF1KB0 PIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLL
1350 1360 1370 1380 1390 1400
1990 2000 2010 2020 2030 2040
pF1KB0 RYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKL
1410 1420 1430 1440 1450 1460
2050 2060 2070 2080 2090 2100
pF1KB0 RETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSL
1470 1480 1490 1500 1510 1520
2110 2120 2130 2140 2150 2160
pF1KB0 CRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWI
1530 1540 1550 1560 1570 1580
2170 2180 2190 2200 2210 2220
pF1KB0 LFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGM
1590 1600 1610 1620 1630 1640
2230 2240 2250 2260 2270 2280
pF1KB0 VYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGI
1650 1660 1670 1680 1690 1700
2290 2300 2310 2320 2330 2340
pF1KB0 TSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREI
1710 1720 1730 1740 1750 1760
2350 2360 2370 2380 2390 2400
pF1KB0 EGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSS
1770 1780 1790 1800 1810 1820
2410 2420 2430 2440 2450 2460
pF1KB0 LVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEK
1830 1840 1850 1860 1870 1880
2470 2480 2490 2500 2510 2520
pF1KB0 RTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIRE
1890 1900 1910 1920 1930 1940
2530 2540 2550 2560 2570 2580
pF1KB0 MFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPI
1950 1960 1970 1980 1990 2000
2590 2600 2610 2620 2630 2640
pF1KB0 GNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLW
2010 2020 2030 2040 2050 2060
2650 2660 2670 2680 2690 2700
pF1KB0 IHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYE
2070 2080 2090 2100 2110 2120
2710 2720 2730 2740 2750 2760
pF1KB0 DLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIG
2130 2140 2150 2160 2170 2180
2770 2780 2790 2800 2810 2820
pF1KB0 GSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQI
2190 2200 2210 2220 2230 2240
2830 2840 2850 2860 2870 2880
pF1KB0 ADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQN
2250 2260 2270 2280 2290 2300
2890 2900 2910 2920 2930 2940
pF1KB0 NLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQEN
2310 2320 2330 2340 2350 2360
2950 2960 2970 2980 2990 3000
pF1KB0 IHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQA
2370 2380 2390 2400 2410 2420
3010 3020 3030 3040 3050 3060
pF1KB0 NKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVT
2430 2440 2450 2460 2470 2480
3070 3080 3090 3100 3110 3120
pF1KB0 ANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVE
2490 2500 2510 2520 2530 2540
3130 3140 3150 3160 3170 3180
pF1KB0 IVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPD
2550 2560 2570 2580 2590 2600
3190 3200 3210 3220 3230 3240
pF1KB0 IIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREV
2610 2620 2630 2640 2650 2660
3250 3260 3270 3280 3290 3300
pF1KB0 AEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDL
2670 2680 2690 2700 2710 2720
3310 3320 3330 3340 3350 3360
pF1KB0 GYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKV
2730 2740 2750 2760 2770 2780
3370 3380 3390 3400 3410 3420
pF1KB0 RDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDY
2790 2800 2810 2820 2830 2840
3430 3440 3450 3460 3470 3480
pF1KB0 LRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFY
2850 2860 2870 2880 2890 2900
3490 3500 3510 3520 3530 3540
pF1KB0 ITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAG
2910 2920 2930 2940 2950 2960
3550 3560 3570 3580 3590 3600
pF1KB0 KRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAR
2970 2980 2990 3000 3010 3020
3610 3620 3630 3640 3650 3660
pF1KB0 EAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLND
3030 3040 3050 3060 3070 3080
3670 3680 3690 3700 3710 3720
pF1KB0 YHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDN
3090 3100 3110 3120 3130 3140
3730 3740 3750 3760 3770 3780
pF1KB0 PCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACN
3150 3160 3170 3180 3190 3200
3790 3800 3810 3820 3830 3840
pF1KB0 EMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPG
3210 3220 3230 3240 3250 3260
3850 3860 3870 3880 3890 3900
pF1KB0 VDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMP
3270 3280 3290 3300 3310 3320
3910 3920 3930 3940 3950 3960
pF1KB0 NLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLM
3330 3340 3350 3360 3370 3380
3970 3980 3990 4000 4010 4020
pF1KB0 SEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLY
3390 3400 3410 3420 3430 3440
4030 4040 4050 4060 4070 4080
pF1KB0 LDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETY
3450 3460 3470 3480 3490 3500
4090 4100 4110 4120 4130 4140
pF1KB0 FIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTR
3510 3520 3530 3540 3550 3560
4150 4160 4170 4180 4190 4200
pF1KB0 AGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTIL
3570 3580 3590 3600 3610 3620
4210 4220 4230 4240 4250 4260
pF1KB0 FSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLAMRVEQF
:::::::::::::::::::::::::::.::::::::::::::::::::::.:::::::::
XP_016 FSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQF
3630 3640 3650 3660 3670 3680
4270 4280 4290 4300 4310 4320
pF1KB0 ELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYP
3690 3700 3710 3720 3730 3740
4330 4340 4350 4360 4370 4380
pF1KB0 PKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCY
3750 3760 3770 3780 3790 3800
4390 4400 4410 4420
pF1KB0 YYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
:::::::::::::::::::::::::::::::::::::::::::
XP_016 YYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
3810 3820 3830 3840
>>XP_016879708 (OMIM: 603333) PREDICTED: dynein heavy ch (3799 aa)
initn: 21620 init1: 21620 opt: 21620 Z-score: 18072.9 bits: 3359.7 E(85289): 0
Smith-Waterman score: 23700; 97.8% identity (97.8% similar) in 3703 aa overlap (51-3671:51-3753)
30 40 50 60 70 80
pF1KB0 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
::::::::::::::::::::::::::::::
XP_016 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB0 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB0 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
150 160 170 180 190 200
210 220 230 240 250 260
pF1KB0 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
210 220 230 240 250 260
270 280 290 300 310 320
pF1KB0 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
270 280 290 300 310 320
330 340 350 360 370 380
pF1KB0 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
330 340 350 360 370 380
390
pF1KB0 RERLTSLFRK--------------------------------------------------
::::::::::
XP_016 RERLTSLFRKMSNEIIRLCCHAISLDRIFEGYVSSSKEDLQGCILCCHAWKDHYVQAVQM
390 400 410 420 430 440
400 410
pF1KB0 --------------------------------VCDCQYHFARWEDGKQGPLPCFFGAQGP
::::::::::::::::::::::::::::
XP_016 HIQFSSRGWVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGKQGPLPCFFGAQGP
450 460 470 480 490 500
420 430 440 450 460 470
pF1KB0 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSA
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSA
510 520 530 540 550 560
480 490 500 510 520 530
pF1KB0 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
570 580 590 600 610 620
540 550 560 570 580 590
pF1KB0 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
630 640 650 660 670 680
600 610 620 630 640 650
pF1KB0 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
690 700 710 720 730 740
660 670 680 690 700 710
pF1KB0 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
750 760 770 780 790 800
720 730 740 750 760 770
pF1KB0 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
810 820 830 840 850 860
780 790 800 810 820 830
pF1KB0 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
870 880 890 900 910 920
840 850 860 870 880 890
pF1KB0 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
930 940 950 960 970 980
900 910 920 930 940 950
pF1KB0 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KB0 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KB0 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110 1120 1130
pF1KB0 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
1170 1180 1190 1200 1210 1220
1140 1150 1160 1170 1180 1190
pF1KB0 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
1230 1240 1250 1260 1270 1280
1200 1210 1220 1230 1240 1250
pF1KB0 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
1290 1300 1310 1320 1330 1340
1260 1270 1280 1290 1300 1310
pF1KB0 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
1350 1360 1370 1380 1390 1400
1320 1330 1340 1350 1360 1370
pF1KB0 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
1410 1420 1430 1440 1450 1460
1380 1390 1400 1410 1420 1430
pF1KB0 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
1470 1480 1490 1500 1510 1520
1440 1450 1460 1470 1480 1490
pF1KB0 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
1530 1540 1550 1560 1570 1580
1500 1510 1520 1530 1540 1550
pF1KB0 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
1590 1600 1610 1620 1630 1640
1560 1570 1580 1590 1600 1610
pF1KB0 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
1650 1660 1670 1680 1690 1700
1620 1630 1640 1650 1660 1670
pF1KB0 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
1710 1720 1730 1740 1750 1760
1680 1690 1700 1710 1720 1730
pF1KB0 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
1770 1780 1790 1800 1810 1820
1740 1750 1760 1770 1780 1790
pF1KB0 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
1830 1840 1850 1860 1870 1880
1800 1810 1820 1830 1840 1850
pF1KB0 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
1890 1900 1910 1920 1930 1940
1860 1870 1880 1890 1900 1910
pF1KB0 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
1950 1960 1970 1980 1990 2000
1920 1930 1940 1950 1960 1970
pF1KB0 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
2010 2020 2030 2040 2050 2060
1980 1990 2000 2010 2020 2030
pF1KB0 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
2070 2080 2090 2100 2110 2120
2040 2050 2060 2070 2080 2090
pF1KB0 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
2130 2140 2150 2160 2170 2180
2100 2110 2120 2130 2140 2150
pF1KB0 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
2190 2200 2210 2220 2230 2240
2160 2170 2180 2190 2200 2210
pF1KB0 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
2250 2260 2270 2280 2290 2300
2220 2230 2240 2250 2260 2270
pF1KB0 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
2310 2320 2330 2340 2350 2360
2280 2290 2300 2310 2320 2330
pF1KB0 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
2370 2380 2390 2400 2410 2420
2340 2350 2360 2370 2380 2390
pF1KB0 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
2430 2440 2450 2460 2470 2480
2400 2410 2420 2430 2440 2450
pF1KB0 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
2490 2500 2510 2520 2530 2540
2460 2470 2480 2490 2500 2510
pF1KB0 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
2550 2560 2570 2580 2590 2600
2520 2530 2540 2550 2560 2570
pF1KB0 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
2610 2620 2630 2640 2650 2660
2580 2590 2600 2610 2620 2630
pF1KB0 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
2670 2680 2690 2700 2710 2720
2640 2650 2660 2670 2680 2690
pF1KB0 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
2730 2740 2750 2760 2770 2780
2700 2710 2720 2730 2740 2750
pF1KB0 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
2790 2800 2810 2820 2830 2840
2760 2770 2780 2790 2800 2810
pF1KB0 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
2850 2860 2870 2880 2890 2900
2820 2830 2840 2850 2860 2870
pF1KB0 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
2910 2920 2930 2940 2950 2960
2880 2890 2900 2910 2920 2930
pF1KB0 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
2970 2980 2990 3000 3010 3020
2940 2950 2960 2970 2980 2990
pF1KB0 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
3030 3040 3050 3060 3070 3080
3000 3010 3020 3030 3040 3050
pF1KB0 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
3090 3100 3110 3120 3130 3140
3060 3070 3080 3090 3100 3110
pF1KB0 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
3150 3160 3170 3180 3190 3200
3120 3130 3140 3150 3160 3170
pF1KB0 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
3210 3220 3230 3240 3250 3260
3180 3190 3200 3210 3220 3230
pF1KB0 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
3270 3280 3290 3300 3310 3320
3240 3250 3260 3270 3280 3290
pF1KB0 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
3330 3340 3350 3360 3370 3380
3300 3310 3320 3330 3340 3350
pF1KB0 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
3390 3400 3410 3420 3430 3440
3360 3370 3380 3390 3400 3410
pF1KB0 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
3450 3460 3470 3480 3490 3500
3420 3430 3440 3450 3460 3470
pF1KB0 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
3510 3520 3530 3540 3550 3560
3480 3490 3500 3510 3520 3530
pF1KB0 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
3570 3580 3590 3600 3610 3620
3540 3550 3560 3570 3580 3590
pF1KB0 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
3630 3640 3650 3660 3670 3680
3600 3610 3620 3630 3640 3650
pF1KB0 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
3690 3700 3710 3720 3730 3740
3660 3670 3680 3690 3700 3710
pF1KB0 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
:::::::::::::
XP_016 IDYLNDYHTYAVYSLGQLLGNFPSPAGRDIITDGLSVLSETVAYSSLCLQDLAECLARQ
3750 3760 3770 3780 3790
>--
initn: 312 init1: 312 opt: 312 Z-score: 257.8 bits: 63.3 E(85289): 1.3e-07
Smith-Waterman score: 312; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)
10 20 30 40 50 60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
XP_016 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
70 80 90 100 110 120
>>XP_011521972 (OMIM: 603333) PREDICTED: dynein heavy ch (3551 aa)
initn: 20302 init1: 20302 opt: 20302 Z-score: 16971.4 bits: 3155.8 E(85289): 0
Smith-Waterman score: 22382; 97.6% identity (97.6% similar) in 3494 aa overlap (51-3462:51-3544)
30 40 50 60 70 80
pF1KB0 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
::::::::::::::::::::::::::::::
XP_011 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB0 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB0 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
150 160 170 180 190 200
210 220 230 240 250 260
pF1KB0 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
210 220 230 240 250 260
270 280 290 300 310 320
pF1KB0 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
270 280 290 300 310 320
330 340 350 360 370 380
pF1KB0 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
330 340 350 360 370 380
390
pF1KB0 RERLTSLFRK--------------------------------------------------
::::::::::
XP_011 RERLTSLFRKMSNEIIRLCCHAISLDRIFEGYVSSSKEDLQGCILCCHAWKDHYVQAVQM
390 400 410 420 430 440
400 410
pF1KB0 --------------------------------VCDCQYHFARWEDGKQGPLPCFFGAQGP
::::::::::::::::::::::::::::
XP_011 HIQFSSRGWVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGKQGPLPCFFGAQGP
450 460 470 480 490 500
420 430 440 450 460 470
pF1KB0 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSA
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSA
510 520 530 540 550 560
480 490 500 510 520 530
pF1KB0 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
570 580 590 600 610 620
540 550 560 570 580 590
pF1KB0 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
630 640 650 660 670 680
600 610 620 630 640 650
pF1KB0 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
690 700 710 720 730 740
660 670 680 690 700 710
pF1KB0 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
750 760 770 780 790 800
720 730 740 750 760 770
pF1KB0 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
810 820 830 840 850 860
780 790 800 810 820 830
pF1KB0 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
870 880 890 900 910 920
840 850 860 870 880 890
pF1KB0 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
930 940 950 960 970 980
900 910 920 930 940 950
pF1KB0 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KB0 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KB0 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110 1120 1130
pF1KB0 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
1170 1180 1190 1200 1210 1220
1140 1150 1160 1170 1180 1190
pF1KB0 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
1230 1240 1250 1260 1270 1280
1200 1210 1220 1230 1240 1250
pF1KB0 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
1290 1300 1310 1320 1330 1340
1260 1270 1280 1290 1300 1310
pF1KB0 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
1350 1360 1370 1380 1390 1400
1320 1330 1340 1350 1360 1370
pF1KB0 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
1410 1420 1430 1440 1450 1460
1380 1390 1400 1410 1420 1430
pF1KB0 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
1470 1480 1490 1500 1510 1520
1440 1450 1460 1470 1480 1490
pF1KB0 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
1530 1540 1550 1560 1570 1580
1500 1510 1520 1530 1540 1550
pF1KB0 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
1590 1600 1610 1620 1630 1640
1560 1570 1580 1590 1600 1610
pF1KB0 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
1650 1660 1670 1680 1690 1700
1620 1630 1640 1650 1660 1670
pF1KB0 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
1710 1720 1730 1740 1750 1760
1680 1690 1700 1710 1720 1730
pF1KB0 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
1770 1780 1790 1800 1810 1820
1740 1750 1760 1770 1780 1790
pF1KB0 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
1830 1840 1850 1860 1870 1880
1800 1810 1820 1830 1840 1850
pF1KB0 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
1890 1900 1910 1920 1930 1940
1860 1870 1880 1890 1900 1910
pF1KB0 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
1950 1960 1970 1980 1990 2000
1920 1930 1940 1950 1960 1970
pF1KB0 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
2010 2020 2030 2040 2050 2060
1980 1990 2000 2010 2020 2030
pF1KB0 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
2070 2080 2090 2100 2110 2120
2040 2050 2060 2070 2080 2090
pF1KB0 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
2130 2140 2150 2160 2170 2180
2100 2110 2120 2130 2140 2150
pF1KB0 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
2190 2200 2210 2220 2230 2240
2160 2170 2180 2190 2200 2210
pF1KB0 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
2250 2260 2270 2280 2290 2300
2220 2230 2240 2250 2260 2270
pF1KB0 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
2310 2320 2330 2340 2350 2360
2280 2290 2300 2310 2320 2330
pF1KB0 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
2370 2380 2390 2400 2410 2420
2340 2350 2360 2370 2380 2390
pF1KB0 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
2430 2440 2450 2460 2470 2480
2400 2410 2420 2430 2440 2450
pF1KB0 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
2490 2500 2510 2520 2530 2540
2460 2470 2480 2490 2500 2510
pF1KB0 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
2550 2560 2570 2580 2590 2600
2520 2530 2540 2550 2560 2570
pF1KB0 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
2610 2620 2630 2640 2650 2660
2580 2590 2600 2610 2620 2630
pF1KB0 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
2670 2680 2690 2700 2710 2720
2640 2650 2660 2670 2680 2690
pF1KB0 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
2730 2740 2750 2760 2770 2780
2700 2710 2720 2730 2740 2750
pF1KB0 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
2790 2800 2810 2820 2830 2840
2760 2770 2780 2790 2800 2810
pF1KB0 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
2850 2860 2870 2880 2890 2900
2820 2830 2840 2850 2860 2870
pF1KB0 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
2910 2920 2930 2940 2950 2960
2880 2890 2900 2910 2920 2930
pF1KB0 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
2970 2980 2990 3000 3010 3020
2940 2950 2960 2970 2980 2990
pF1KB0 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
3030 3040 3050 3060 3070 3080
3000 3010 3020 3030 3040 3050
pF1KB0 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
3090 3100 3110 3120 3130 3140
3060 3070 3080 3090 3100 3110
pF1KB0 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
3150 3160 3170 3180 3190 3200
3120 3130 3140 3150 3160 3170
pF1KB0 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
3210 3220 3230 3240 3250 3260
3180 3190 3200 3210 3220 3230
pF1KB0 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
3270 3280 3290 3300 3310 3320
3240 3250 3260 3270 3280 3290
pF1KB0 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
3330 3340 3350 3360 3370 3380
3300 3310 3320 3330 3340 3350
pF1KB0 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
3390 3400 3410 3420 3430 3440
3360 3370 3380 3390 3400 3410
pF1KB0 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
3450 3460 3470 3480 3490 3500
3420 3430 3440 3450 3460 3470
pF1KB0 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIDSPGLGP
3510 3520 3530 3540 3550
3480 3490 3500 3510 3520 3530
pF1KB0 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
>--
initn: 312 init1: 312 opt: 312 Z-score: 258.2 bits: 63.3 E(85289): 1.2e-07
Smith-Waterman score: 312; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)
10 20 30 40 50 60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
XP_011 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
70 80 90 100 110 120
>>XP_011521968 (OMIM: 603333) PREDICTED: dynein heavy ch (4446 aa)
initn: 14541 init1: 14378 opt: 14378 Z-score: 12017.1 bits: 2239.4 E(85289): 0
Smith-Waterman score: 28307; 96.7% identity (96.7% similar) in 4459 aa overlap (51-4427:51-4446)
30 40 50 60 70 80
pF1KB0 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
::::::::::::::::::::::::::::::
XP_011 WSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEGPQAQSEESVEPEADVKPLF
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB0 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVY
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB0 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASH
150 160 170 180 190 200
210 220 230 240 250 260
pF1KB0 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEML
210 220 230 240 250 260
270 280 290 300 310 320
pF1KB0 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMK
270 280 290 300 310 320
330 340 350 360 370 380
pF1KB0 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNT
330 340 350 360 370 380
390
pF1KB0 RERLTSLFRK--------------------------------------------------
::::::::::
XP_011 RERLTSLFRKMSNEIIRLCCHAISLDRIFEGYVSSSKEDLQGCILCCHAWKDHYVQAVQM
390 400 410 420 430 440
400 410
pF1KB0 --------------------------------VCDCQYHFARWEDGKQGPLPCFFGAQGP
::::::::::::::::::::::::::::
XP_011 HIQFSSRGWVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGKQGPLPCFFGAQGP
450 460 470 480 490 500
420 430 440 450 460 470
pF1KB0 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDPEVMTQNLITSA
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 QITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSA
510 520 530 540 550 560
480 490 500 510 520 530
pF1KB0 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE
570 580 590 600 610 620
540 550 560 570 580 590
pF1KB0 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKT
630 640 650 660 670 680
600 610 620 630 640 650
pF1KB0 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYV
690 700 710 720 730 740
660 670 680 690 700 710
pF1KB0 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWA
750 760 770 780 790 800
720 730 740 750 760 770
pF1KB0 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFE
810 820 830 840 850 860
780 790 800 810 820 830
pF1KB0 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRL
870 880 890 900 910 920
840 850 860 870 880 890
pF1KB0 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGN
930 940 950 960 970 980
900 910 920 930 940 950
pF1KB0 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKT
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KB0 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCS
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KB0 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLV
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110 1120 1130
pF1KB0 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQML
1170 1180 1190 1200 1210 1220
1140 1150 1160 1170 1180 1190
pF1KB0 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMRE
1230 1240 1250 1260 1270 1280
1200 1210 1220 1230 1240 1250
pF1KB0 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTE
1290 1300 1310 1320 1330 1340
1260 1270 1280 1290 1300 1310
pF1KB0 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQ
1350 1360 1370 1380 1390 1400
1320 1330 1340 1350 1360 1370
pF1KB0 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVT
1410 1420 1430 1440 1450 1460
1380 1390 1400 1410 1420 1430
pF1KB0 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILE
1470 1480 1490 1500 1510 1520
1440 1450 1460 1470 1480 1490
pF1KB0 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTH
1530 1540 1550 1560 1570 1580
1500 1510 1520 1530 1540 1550
pF1KB0 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPH
1590 1600 1610 1620 1630 1640
1560 1570 1580 1590 1600 1610
pF1KB0 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMR
1650 1660 1670 1680 1690 1700
1620 1630 1640 1650 1660 1670
pF1KB0 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKI
1710 1720 1730 1740 1750 1760
1680 1690 1700 1710 1720 1730
pF1KB0 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFD
1770 1780 1790 1800 1810 1820
1740 1750 1760 1770 1780 1790
pF1KB0 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRG
1830 1840 1850 1860 1870 1880
1800 1810 1820 1830 1840 1850
pF1KB0 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFN
1890 1900 1910 1920 1930 1940
1860 1870 1880 1890 1900 1910
pF1KB0 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPEN
1950 1960 1970 1980 1990 2000
1920 1930 1940 1950 1960 1970
pF1KB0 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLR
2010 2020 2030 2040 2050 2060
1980 1990 2000 2010 2020 2030
pF1KB0 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPV
2070 2080 2090 2100 2110 2120
2040 2050 2060 2070 2080 2090
pF1KB0 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQ
2130 2140 2150 2160 2170 2180
2100 2110 2120 2130 2140 2150
pF1KB0 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEK
2190 2200 2210 2220 2230 2240
2160 2170 2180 2190 2200 2210
pF1KB0 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPAT
2250 2260 2270 2280 2290 2300
2220 2230 2240 2250 2260 2270
pF1KB0 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPL
2310 2320 2330 2340 2350 2360
2280 2290 2300 2310 2320 2330
pF1KB0 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRID
2370 2380 2390 2400 2410 2420
2340 2350 2360 2370 2380 2390
pF1KB0 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRY
2430 2440 2450 2460 2470 2480
2400 2410 2420 2430 2440 2450
pF1KB0 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSII
2490 2500 2510 2520 2530 2540
2460 2470 2480 2490 2500 2510
pF1KB0 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQT
2550 2560 2570 2580 2590 2600
2520 2530 2540 2550 2560 2570
pF1KB0 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFE
::::::::::::::::::::::::::::::::::::::::
XP_011 IKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPT--------------------
2610 2620 2630 2640
2580 2590 2600 2610 2620 2630
pF1KB0 EEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKS
:::::::::::::::::
XP_011 -------------------------------------------VFQGMLRANKDFHDTKS
2650
2640 2650 2660 2670 2680 2690
pF1KB0 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLK
2660 2670 2680 2690 2700 2710
2700 2710 2720 2730 2740 2750
pF1KB0 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNM
2720 2730 2740 2750 2760 2770
2760 2770 2780 2790 2800 2810
pF1KB0 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFI
2780 2790 2800 2810 2820 2830
2820 2830 2840 2850 2860 2870
pF1KB0 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYL
2840 2850 2860 2870 2880 2890
2880 2890 2900 2910 2920 2930
pF1KB0 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVD
2900 2910 2920 2930 2940 2950
2940 2950 2960 2970 2980 2990
pF1KB0 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQ
2960 2970 2980 2990 3000 3010
3000 3010 3020 3030 3040 3050
pF1KB0 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADE
3020 3030 3040 3050 3060 3070
3060 3070 3080 3090 3100 3110
pF1KB0 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGR
3080 3090 3100 3110 3120 3130
3120 3130 3140 3150 3160 3170
pF1KB0 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQ
3140 3150 3160 3170 3180 3190
3180 3190 3200 3210 3220 3230
pF1KB0 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQ
3200 3210 3220 3230 3240 3250
3240 3250 3260 3270 3280 3290
pF1KB0 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQ
3260 3270 3280 3290 3300 3310
3300 3310 3320 3330 3340 3350
pF1KB0 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFL
3320 3330 3340 3350 3360 3370
3360 3370 3380 3390 3400 3410
pF1KB0 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIID
3380 3390 3400 3410 3420 3430
3420 3430 3440 3450 3460 3470
pF1KB0 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYN
3440 3450 3460 3470 3480 3490
3480 3490 3500 3510 3520 3530
pF1KB0 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLV
3500 3510 3520 3530 3540 3550
3540 3550 3560 3570 3580 3590
pF1KB0 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEI
3560 3570 3580 3590 3600 3610
3600 3610 3620 3630 3640 3650
pF1KB0 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDR
3620 3630 3640 3650 3660 3670
3660 3670 3680 3690 3700 3710
pF1KB0 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDR
3680 3690 3700 3710 3720 3730
3720 3730 3740 3750 3760 3770
pF1KB0 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGE
3740 3750 3760 3770 3780 3790
3780 3790 3800 3810 3820 3830
pF1KB0 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLV
3800 3810 3820 3830 3840 3850
3840 3850 3860 3870 3880 3890
pF1KB0 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHL
3860 3870 3880 3890 3900 3910
3900 3910 3920 3930 3940 3950
pF1KB0 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMT
3920 3930 3940 3950 3960 3970
3960 3970 3980 3990 4000 4010
pF1KB0 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSE
3980 3990 4000 4010 4020 4030
4020 4030 4040 4050 4060 4070
pF1KB0 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRL
4040 4050 4060 4070 4080 4090
4080 4090 4100 4110 4120 4130
pF1KB0 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQP
4100 4110 4120 4130 4140 4150
4140 4150 4160 4170 4180 4190
pF1KB0 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNT
4160 4170 4180 4190 4200 4210
4200 4210 4220 4230 4240 4250
pF1KB0 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCILDAHVPPLWGKAYPSQKPLAAWTQDLA
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::.:::
XP_011 LMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLA
4220 4230 4240 4250 4260 4270
4260 4270 4280 4290 4300 4310
pF1KB0 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDD
4280 4290 4300 4310 4320 4330
4320 4330 4340 4350 4360 4370
pF1KB0 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGM
4340 4350 4360 4370 4380 4390
4380 4390 4400 4410 4420
pF1KB0 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
4400 4410 4420 4430 4440
>--
initn: 312 init1: 312 opt: 312 Z-score: 256.8 bits: 63.3 E(85289): 1.4e-07
Smith-Waterman score: 312; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)
10 20 30 40 50 60
pF1KB0 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
XP_011 GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
70 80 90 100 110 120
4427 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:03:05 2016 done: Fri Nov 4 02:03:10 2016
Total Scan time: 28.400 Total Display time: 6.010
Function used was FASTA [36.3.4 Apr, 2011]