Result of FASTA (omim) for
pF1KB0869
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0869, 1074 aa
1>>>pF1KB0869 1074 - 1074 aa - 1074 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2463+/-0.000527; mu= 17.4591+/- 0.032
mean_var=123.9871+/-23.600, 0's: 0 Z-trim(112.8): 428 B-trim: 100 in 1/50
Lambda= 0.115182
statistics sampled from 21345 (21839) to 21345 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.256), width: 16
Scan time: 14.240
The best scores are: opt bits E(85289)
XP_011512458 (OMIM: 609297) PREDICTED: semaphorin- (1074) 7681 1289.2 0
XP_011512457 (OMIM: 609297) PREDICTED: semaphorin- (1074) 7681 1289.2 0
XP_011512459 (OMIM: 609297) PREDICTED: semaphorin- (1074) 7681 1289.2 0
XP_011512460 (OMIM: 609297) PREDICTED: semaphorin- (1074) 7681 1289.2 0
NP_003957 (OMIM: 609297) semaphorin-5A precursor [ (1074) 7681 1289.2 0
XP_006714569 (OMIM: 609297) PREDICTED: semaphorin- (1074) 7681 1289.2 0
XP_006714570 (OMIM: 609297) PREDICTED: semaphorin- (1074) 7681 1289.2 0
XP_011512461 (OMIM: 609297) PREDICTED: semaphorin- (1027) 7067 1187.1 0
XP_016865505 (OMIM: 609297) PREDICTED: semaphorin- ( 917) 6605 1110.3 0
NP_001243275 (OMIM: 609298) semaphorin-5B isoform (1151) 4720 797.2 0
NP_001026872 (OMIM: 609298) semaphorin-5B isoform (1151) 4720 797.2 0
NP_001243276 (OMIM: 609298) semaphorin-5B isoform (1205) 4720 797.2 0
XP_016862127 (OMIM: 609298) PREDICTED: semaphorin- (1117) 4415 746.5 2e-214
NP_001243277 (OMIM: 609298) semaphorin-5B isoform (1057) 3948 668.8 4.4e-191
XP_016862128 (OMIM: 609298) PREDICTED: semaphorin- ( 794) 3617 613.7 1.3e-174
XP_011525943 (OMIM: 608873) PREDICTED: semaphorin- ( 578) 894 161.1 1.7e-38
XP_005272099 (OMIM: 605885) PREDICTED: semaphorin- ( 975) 895 161.5 2.2e-38
NP_065847 (OMIM: 605885) semaphorin-6A isoform 2 p (1030) 895 161.5 2.3e-38
NP_115484 (OMIM: 608873) semaphorin-6B precursor [ ( 888) 894 161.3 2.3e-38
NP_001287709 (OMIM: 605885) semaphorin-6A isoform (1047) 895 161.5 2.3e-38
XP_011525941 (OMIM: 608873) PREDICTED: semaphorin- ( 894) 894 161.3 2.3e-38
XP_011525942 (OMIM: 608873) PREDICTED: semaphorin- ( 894) 894 161.3 2.3e-38
XP_006714726 (OMIM: 605885) PREDICTED: semaphorin- (1052) 895 161.5 2.3e-38
XP_016865164 (OMIM: 605885) PREDICTED: semaphorin- (1052) 895 161.5 2.3e-38
XP_011508173 (OMIM: 607292,610282,610283) PREDICTE ( 723) 867 156.7 4.5e-37
NP_001180229 (OMIM: 607292,610282,610283) semaphor ( 761) 867 156.7 4.6e-37
XP_016857545 (OMIM: 607292,610282,610283) PREDICTE ( 761) 867 156.7 4.6e-37
NP_001180230 (OMIM: 607292,610282,610283) semaphor ( 761) 867 156.7 4.6e-37
NP_071762 (OMIM: 607292,610282,610283) semaphorin- ( 761) 867 156.7 4.6e-37
XP_011508175 (OMIM: 607292,610282,610283) PREDICTE ( 761) 867 156.7 4.6e-37
XP_011508174 (OMIM: 607292,610282,610283) PREDICTE ( 761) 867 156.7 4.6e-37
XP_011508177 (OMIM: 607292,610282,610283) PREDICTE ( 662) 866 156.5 4.7e-37
XP_011508180 (OMIM: 607292,610282,610283) PREDICTE ( 662) 866 156.5 4.7e-37
XP_011508176 (OMIM: 607292,610282,610283) PREDICTE ( 662) 866 156.5 4.7e-37
XP_011508178 (OMIM: 607292,610282,610283) PREDICTE ( 662) 866 156.5 4.7e-37
NP_079242 (OMIM: 609295) semaphorin-6D isoform 6 p ( 476) 852 154.0 1.9e-36
NP_705872 (OMIM: 609295) semaphorin-6D isoform 5 p ( 597) 852 154.1 2.2e-36
XP_016878110 (OMIM: 609295) PREDICTED: semaphorin- ( 998) 852 154.3 3.2e-36
XP_011520383 (OMIM: 609295) PREDICTED: semaphorin- ( 998) 852 154.3 3.2e-36
NP_705869 (OMIM: 609295) semaphorin-6D isoform 2 p ( 998) 852 154.3 3.2e-36
NP_065909 (OMIM: 609295) semaphorin-6D isoform 1 p (1011) 852 154.3 3.2e-36
XP_011520382 (OMIM: 609295) PREDICTED: semaphorin- (1011) 852 154.3 3.2e-36
NP_001185928 (OMIM: 609295) semaphorin-6D isoform (1011) 852 154.3 3.2e-36
NP_705870 (OMIM: 609295) semaphorin-6D isoform 3 p (1017) 852 154.3 3.2e-36
XP_011520381 (OMIM: 609295) PREDICTED: semaphorin- (1017) 852 154.3 3.2e-36
XP_016878109 (OMIM: 609295) PREDICTED: semaphorin- (1017) 852 154.3 3.2e-36
XP_011520380 (OMIM: 609295) PREDICTED: semaphorin- (1030) 852 154.4 3.2e-36
XP_016878108 (OMIM: 609295) PREDICTED: semaphorin- (1030) 852 154.4 3.2e-36
XP_005254746 (OMIM: 609295) PREDICTED: semaphorin- (1054) 852 154.4 3.3e-36
XP_011520379 (OMIM: 609295) PREDICTED: semaphorin- (1054) 852 154.4 3.3e-36
>>XP_011512458 (OMIM: 609297) PREDICTED: semaphorin-5A i (1074 aa)
initn: 7681 init1: 7681 opt: 7681 Z-score: 6903.9 bits: 1289.2 E(85289): 0
Smith-Waterman score: 7681; 100.0% identity (100.0% similar) in 1074 aa overlap (1-1074:1-1074)
10 20 30 40 50 60
pF1KB0 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB0 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
1030 1040 1050 1060 1070
>>XP_011512457 (OMIM: 609297) PREDICTED: semaphorin-5A i (1074 aa)
initn: 7681 init1: 7681 opt: 7681 Z-score: 6903.9 bits: 1289.2 E(85289): 0
Smith-Waterman score: 7681; 100.0% identity (100.0% similar) in 1074 aa overlap (1-1074:1-1074)
10 20 30 40 50 60
pF1KB0 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB0 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
1030 1040 1050 1060 1070
>>XP_011512459 (OMIM: 609297) PREDICTED: semaphorin-5A i (1074 aa)
initn: 7681 init1: 7681 opt: 7681 Z-score: 6903.9 bits: 1289.2 E(85289): 0
Smith-Waterman score: 7681; 100.0% identity (100.0% similar) in 1074 aa overlap (1-1074:1-1074)
10 20 30 40 50 60
pF1KB0 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB0 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
1030 1040 1050 1060 1070
>>XP_011512460 (OMIM: 609297) PREDICTED: semaphorin-5A i (1074 aa)
initn: 7681 init1: 7681 opt: 7681 Z-score: 6903.9 bits: 1289.2 E(85289): 0
Smith-Waterman score: 7681; 100.0% identity (100.0% similar) in 1074 aa overlap (1-1074:1-1074)
10 20 30 40 50 60
pF1KB0 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB0 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
1030 1040 1050 1060 1070
>>NP_003957 (OMIM: 609297) semaphorin-5A precursor [Homo (1074 aa)
initn: 7681 init1: 7681 opt: 7681 Z-score: 6903.9 bits: 1289.2 E(85289): 0
Smith-Waterman score: 7681; 100.0% identity (100.0% similar) in 1074 aa overlap (1-1074:1-1074)
10 20 30 40 50 60
pF1KB0 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB0 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
1030 1040 1050 1060 1070
>>XP_006714569 (OMIM: 609297) PREDICTED: semaphorin-5A i (1074 aa)
initn: 7681 init1: 7681 opt: 7681 Z-score: 6903.9 bits: 1289.2 E(85289): 0
Smith-Waterman score: 7681; 100.0% identity (100.0% similar) in 1074 aa overlap (1-1074:1-1074)
10 20 30 40 50 60
pF1KB0 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB0 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
1030 1040 1050 1060 1070
>>XP_006714570 (OMIM: 609297) PREDICTED: semaphorin-5A i (1074 aa)
initn: 7681 init1: 7681 opt: 7681 Z-score: 6903.9 bits: 1289.2 E(85289): 0
Smith-Waterman score: 7681; 100.0% identity (100.0% similar) in 1074 aa overlap (1-1074:1-1074)
10 20 30 40 50 60
pF1KB0 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHII
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KB0 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
1030 1040 1050 1060 1070
>>XP_011512461 (OMIM: 609297) PREDICTED: semaphorin-5A i (1027 aa)
initn: 7067 init1: 7067 opt: 7067 Z-score: 6352.7 bits: 1187.1 E(85289): 0
Smith-Waterman score: 7067; 99.9% identity (100.0% similar) in 985 aa overlap (90-1074:43-1027)
60 70 80 90 100 110
pF1KB0 QLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIR
.:::::::::::::::::::::::::::::
XP_011 PHTPHKATWESRGRRVEHHRAVGGRPYSGRKAVEWECDEATKKACYSKGKSKEECQNYIR
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB0 VLLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGEL
80 90 100 110 120 130
180 190 200 210 220 230
pF1KB0 YAATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVE
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB0 HDCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HDCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPE
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB0 LDLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGT
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB0 VDQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDQGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHI
320 330 340 350 360 370
420 430 440 450 460 470
pF1KB0 IYLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHV
380 390 400 410 420 430
480 490 500 510 520 530
pF1KB0 VKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTV
440 450 460 470 480 490
540 550 560 570 580 590
pF1KB0 DGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWT
500 510 520 530 540 550
600 610 620 630 640 650
pF1KB0 PWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGW
560 570 580 590 600 610
660 670 680 690 700 710
pF1KB0 GPWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNIS
620 630 640 650 660 670
720 730 740 750 760 770
pF1KB0 DNGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYS
680 690 700 710 720 730
780 790 800 810 820 830
pF1KB0 AHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCP
740 750 760 770 780 790
840 850 860 870 880 890
pF1KB0 VDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESW
800 810 820 830 840 850
900 910 920 930 940 950
pF1KB0 SEWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVE
860 870 880 890 900 910
960 970 980 990 1000 1010
pF1KB0 EKRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRCGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSIT
920 930 940 950 960 970
1020 1030 1040 1050 1060 1070
pF1KB0 NHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
980 990 1000 1010 1020
>>XP_016865505 (OMIM: 609297) PREDICTED: semaphorin-5A i (917 aa)
initn: 6605 init1: 6605 opt: 6605 Z-score: 5938.5 bits: 1110.3 E(85289): 0
Smith-Waterman score: 6605; 100.0% identity (100.0% similar) in 917 aa overlap (158-1074:1-917)
130 140 150 160 170 180
pF1KB0 LFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELYAATAMDF
::::::::::::::::::::::::::::::
XP_016 MARCPYSPQHNSTALLTAGGELYAATAMDF
10 20 30
190 200 210 220 230 240
pF1KB0 PGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHDCGKTVF
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB0 SRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPELDLIYGIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPELDLIYGIF
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB0 TTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTVDQGLYVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGTVDQGLYVN
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB0 LTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHIIYLATDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHIIYLATDYG
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB0 TIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRC
280 290 300 310 320 330
490 500 510 520 530 540
pF1KB0 QFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVDGHFGVWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLTVDGHFGVWS
340 350 360 370 380 390
550 560 570 580 590 600
pF1KB0 PWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTPWTSWSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGWTPWTSWSPC
400 410 420 430 440 450
610 620 630 640 650 660
pF1KB0 STTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWGPWERCTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTGWGPWERCTA
460 470 480 490 500 510
670 680 690 700 710 720
pF1KB0 QCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISDNGGHYEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISDNGGHYEQ
520 530 540 550 560 570
730 740 750 760 770 780
pF1KB0 RFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAW
580 590 600 610 620 630
790 800 810 820 830 840
pF1KB0 SAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPVDGVWSCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPVDGVWSCW
640 650 660 670 680 690
850 860 870 880 890 900
pF1KB0 SPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWSEWSDWSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPESWSEWSDWSE
700 710 720 730 740 750
910 920 930 940 950 960
pF1KB0 CEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEEKRCGEFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSVEEKRCGEFN
760 770 780 790 800 810
970 980 990 1000 1010 1020
pF1KB0 MFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITNHINKLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTSITNHINKLDK
820 830 840 850 860 870
1030 1040 1050 1060 1070
pF1KB0 YDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYFTDLNNYDEY
880 890 900 910
>>NP_001243275 (OMIM: 609298) semaphorin-5B isoform 1 [H (1151 aa)
initn: 4654 init1: 2798 opt: 4720 Z-score: 4244.3 bits: 797.2 E(85289): 0
Smith-Waterman score: 4720; 59.1% identity (83.8% similar) in 1045 aa overlap (30-1071:98-1135)
10 20 30 40 50
pF1KB0 MKGTCVIAWLFSSLGLWRLAHPEAQGTTQCQRTEHPVISYKEIGPWLREFRAKNAVDFS
: ..::....... ::. .: .: :::
NP_001 SLLLPSLTLLVSHLSSSQDVSSEPSSEQQLCALSKHPTVAFEDLQPWVSNFTYPGARDFS
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB0 QLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSKGKSKEECQNYIR
::..::. ..:.::::::::::.: ..::.::.:: .: :...: ::::..::::::.:
NP_001 QLALDPSGNQLIVGARNYLFRLSLANVSLLQATEWASSEDTRRSCQSKGKTEEECQNYVR
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB0 VLLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGEL
::.:.: ..: ::::::.:.::.:...::.. ..:.:.:::::.:.:::::.... :::
NP_001 VLIVAGRKVFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNSTAVISSQGEL
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB0 YAATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVE
::::..:: ::::::::::: :::::::::::::::::::..:::: :.:::.::::::
NP_001 YAATVIDFSGRDPAIYRSLGSGPPLRTAQYNSKWLNEPNFVAAYDIGLFAYFFLRENAVE
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB0 HDCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPE
::::.::.::.:::::::.:::::::::::::::::::::::::::::::::::.: :::
NP_001 HDCGRTVYSRVARVCKNDVGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSAFHLPE
310 320 330 340 350 360
300 310 320 330 340 350
pF1KB0 LDLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPNPNPHFQCGT
:::::.::::::::::::::.::::::.:::.:::.:::: :.:::: :: :.:::::
NP_001 QDLIYGVFTTNVNSIAASAVCAFNLSAISQAFNGPFRYQENPRAAWLPIANPIPNFQCGT
370 380 390 400 410 420
360 370 380 390 400 410
pF1KB0 VDQ-GLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVH
. . : :::::.:::::...:: :.::::: : .:. ::::..::.::....: :
NP_001 LPETGPNENLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYH
430 440 450 460 470 480
420 430 440 450 460 470
pF1KB0 IIYLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREH
..:..:. ::: :. ... .: :::....: ::::.:::.:::: .::::::.
NP_001 VLYIGTESGTILKALSTASRSLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDG
490 500 510 520 530 540
480 490 500 510 520 530
pF1KB0 VVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLEESLSMTQWEQSISACPTRNLT
:...::.:: ::....:.::.::::::: ...:..::.: .:. : :.:.:::.::.:
NP_001 VLRVPLERCAAYRSQGACLGARDPYCGWDGKQQRCSTLEDSSNMSLWTQNITACPVRNVT
550 560 570 580 590 600
540 550 560 570 580 590
pF1KB0 VDGHFGVWSPWTPCTHTDGSAVGSCLCRTRSCDSPAPQCGGWQCEGPGMEIANCSRNGGW
:: :: :::: :: : ::. ::::::.:::::: :.::: .: ::...::::::::.:
NP_001 RDGGFGPWSPWQPCEHLDGDNSGSCLCRARSCDSPRPRCGGLDCLGPAIHIANCSRNGAW
610 620 630 640 650 660
600 610 620 630 640 650
pF1KB0 TPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMFWTG
:::.::. :::.:::::::::::::::.::::::.:::..::::.:::. :: .::..
NP_001 TPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVPIFWAS
670 680 690 700 710 720
660 670 680 690 700 710
pF1KB0 WGPWERCTAQCGGGIQARRRICENGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNI
:: : .:...::::.:.::: :::: .: ::.::...:: . :::....:::::: :::.
NP_001 WGSWSKCSSNCGGGMQSRRRACENGNSCLGCGVEFKTCNPEGCPEVRRNTPWTPWLPVNV
730 740 750 760 770 780
720 730 740 750 760 770
pF1KB0 SDNGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRY
...:.. :::::.::.: ::::. :. ::.: : : : .::...:.::.: .::.:
NP_001 TQGGARQEQRFRFTCRAPLADPHGLQFGRRRTETRTCPADGSGSCDTDALVEVLLRSGST
790 800 810 820 830 840
780 790 800 810 820 830
pF1KB0 SAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPC
: :::.:.:.:: ::.::::: :.: :::.:.::::. ::.::.: . :::.:: :
NP_001 SPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQAC
850 860 870 880 890 900
840 850 860 870 880 890
pF1KB0 PVDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCPES
:: :.::::. :. :::.::::::.:::::..:::. : ::::::::::::: :: :::.
NP_001 PVRGAWSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACPEG
910 920 930 940 950 960
900 910 920 930 940 950
pF1KB0 WSEWSDWSECEASGVQVRARQCILLFPMGSQCSGNTTESRPCVFDSNFIPEVSVARSSSV
:: ::.::.: .:.: :.:.: :.: .: :.::...:::: .. :: . : ::.
NP_001 WSPWSEWSKCTDDGAQSRSRHCEELLPGSSACAGNSSQSRPCPYSE--IPVILPA--SSM
970 980 990 1000 1010 1020
960 970 980 990 1000 1010
pF1KB0 EEKR-CGEFNMFHMIAVGLSSSILGCLLTLLVYTYCQRYQQQSHDATVIHPVSPAPLNTS
:: :. ::..:..:.:.: . . :::: :: ::. :.::...:..::..: :. .
NP_001 EEATDCAGFNLIHLVATGISCFLGSGLLTLAVYLSCQHCQRQSQESTLVHPATPNHLHYK
1030 1040 1050 1060 1070 1080
1020 1030 1040 1050 1060 1070
pF1KB0 ITNHINKLDKYDSVEAIKAFNKNNLILEERNKYFNPHLTGKTYSNAYF-TDLNNYDEY
. : .:: .: .:..:::::: ..: ... : ..:...:. . ::..
NP_001 -GGGTPKNEKYTPME-FKTLNKNNLIPDDRANFY-PLQQTNVYTTTYYPSPLNKHSFRPE
1090 1100 1110 1120 1130 1140
NP_001 ASPGQRCFPNS
1150
1074 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 11:46:30 2016 done: Thu Nov 3 11:46:32 2016
Total Scan time: 14.240 Total Display time: 0.450
Function used was FASTA [36.3.4 Apr, 2011]