FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0901, 80 aa 1>>>pF1KB0901 80 - 80 aa - 80 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.3828+/-0.000224; mu= 13.7925+/- 0.014 mean_var=55.7161+/-11.183, 0's: 0 Z-trim(123.9): 32 B-trim: 1966 in 1/52 Lambda= 0.171824 statistics sampled from 44559 (44598) to 44559 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.864), E-opt: 0.2 (0.523), width: 16 Scan time: 4.330 The best scores are: opt bits E(85289) NP_071289 (OMIM: 606684) FXYD domain-containing io ( 80) 531 137.9 1.7e-33 NP_001265646 (OMIM: 602359) phospholemman precurso ( 92) 176 49.9 5.9e-07 NP_005022 (OMIM: 602359) phospholemman precursor [ ( 92) 176 49.9 5.9e-07 XP_016882363 (OMIM: 602359) PREDICTED: phospholemm ( 92) 176 49.9 5.9e-07 NP_001265647 (OMIM: 602359) phospholemman precurso ( 92) 176 49.9 5.9e-07 NP_068702 (OMIM: 602359) phospholemman precursor [ ( 92) 176 49.9 5.9e-07 XP_016882364 (OMIM: 602359) PREDICTED: phospholemm ( 110) 176 50.0 6.8e-07 XP_016882365 (OMIM: 602359) PREDICTED: phospholemm ( 110) 176 50.0 6.8e-07 NP_071286 (OMIM: 606683) FXYD domain-containing io ( 95) 145 42.2 0.00013 NP_001158308 (OMIM: 606683) FXYD domain-containing ( 95) 145 42.2 0.00013 NP_001158304 (OMIM: 606683) FXYD domain-containing ( 95) 145 42.2 0.00013 NP_001158303 (OMIM: 606683) FXYD domain-containing ( 95) 145 42.2 0.00013 NP_001158309 (OMIM: 606683) FXYD domain-containing ( 95) 145 42.2 0.00013 NP_067614 (OMIM: 154020,601814) sodium/potassium-t ( 64) 140 40.9 0.00022 NP_001671 (OMIM: 154020,601814) sodium/potassium-t ( 66) 140 40.9 0.00022 XP_016882366 (OMIM: 604996) PREDICTED: FXYD domain ( 87) 135 39.7 0.00065 XP_016882367 (OMIM: 604996) PREDICTED: FXYD domain ( 87) 135 39.7 0.00065 NP_005962 (OMIM: 604996) FXYD domain-containing io ( 87) 135 39.7 0.00065 NP_001129483 (OMIM: 604996) FXYD domain-containing ( 87) 135 39.7 0.00065 NP_001129479 (OMIM: 604996) FXYD domain-containing ( 144) 135 39.9 0.00095 NP_001171892 (OMIM: 616926) FXYD domain-containing ( 89) 128 38.0 0.0022 NP_775183 (OMIM: 616926) FXYD domain-containing io ( 89) 128 38.0 0.0022 NP_001307842 (OMIM: 606669) FXYD domain-containing ( 147) 129 38.4 0.0027 NP_054883 (OMIM: 606669) FXYD domain-containing io ( 178) 129 38.5 0.0031 NP_001158077 (OMIM: 606669) FXYD domain-containing ( 178) 129 38.5 0.0031 NP_659003 (OMIM: 606669) FXYD domain-containing io ( 178) 129 38.5 0.0031 >>NP_071289 (OMIM: 606684) FXYD domain-containing ion tr (80 aa) initn: 531 init1: 531 opt: 531 Z-score: 722.2 bits: 137.9 E(85289): 1.7e-33 Smith-Waterman score: 531; 100.0% identity (100.0% similar) in 80 aa overlap (1-80:1-80) 10 20 30 40 50 60 pF1KB0 MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKKVKCRKADSRSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKKVKCRKADSRSES 10 20 30 40 50 60 70 80 pF1KB0 PTCKSCKSELPSSAPGGGGV :::::::::::::::::::: NP_071 PTCKSCKSELPSSAPGGGGV 70 80 >>NP_001265646 (OMIM: 602359) phospholemman precursor [H (92 aa) initn: 153 init1: 153 opt: 176 Z-score: 245.8 bits: 49.9 E(85289): 5.9e-07 Smith-Waterman score: 176; 43.1% identity (81.0% similar) in 58 aa overlap (5-61:16-73) 10 20 30 40 pF1KB0 MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKKV :.. ...:.: ::: :::...: :...: :::.::::::.:.. NP_001 MASLGHILVFCVGLLTMAKAESPKEHDPFTYDYQSLQIGGLVIAGILFILGILIVLSRRC 10 20 30 40 50 60 50 60 70 80 pF1KB0 KCR-KADSRSESPTCKSCKSELPSSAPGGGGV .:. . ..:. : NP_001 RCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR 70 80 90 >>NP_005022 (OMIM: 602359) phospholemman precursor [Homo (92 aa) initn: 153 init1: 153 opt: 176 Z-score: 245.8 bits: 49.9 E(85289): 5.9e-07 Smith-Waterman score: 176; 43.1% identity (81.0% similar) in 58 aa overlap (5-61:16-73) 10 20 30 40 pF1KB0 MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKKV :.. ...:.: ::: :::...: :...: :::.::::::.:.. NP_005 MASLGHILVFCVGLLTMAKAESPKEHDPFTYDYQSLQIGGLVIAGILFILGILIVLSRRC 10 20 30 40 50 60 50 60 70 80 pF1KB0 KCR-KADSRSESPTCKSCKSELPSSAPGGGGV .:. . ..:. : NP_005 RCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR 70 80 90 >>XP_016882363 (OMIM: 602359) PREDICTED: phospholemman i (92 aa) initn: 153 init1: 153 opt: 176 Z-score: 245.8 bits: 49.9 E(85289): 5.9e-07 Smith-Waterman score: 176; 43.1% identity (81.0% similar) in 58 aa overlap (5-61:16-73) 10 20 30 40 pF1KB0 MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKKV :.. ...:.: ::: :::...: :...: :::.::::::.:.. XP_016 MASLGHILVFCVGLLTMAKAESPKEHDPFTYDYQSLQIGGLVIAGILFILGILIVLSRRC 10 20 30 40 50 60 50 60 70 80 pF1KB0 KCR-KADSRSESPTCKSCKSELPSSAPGGGGV .:. . ..:. : XP_016 RCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR 70 80 90 >>NP_001265647 (OMIM: 602359) phospholemman precursor [H (92 aa) initn: 153 init1: 153 opt: 176 Z-score: 245.8 bits: 49.9 E(85289): 5.9e-07 Smith-Waterman score: 176; 43.1% identity (81.0% similar) in 58 aa overlap (5-61:16-73) 10 20 30 40 pF1KB0 MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKKV :.. ...:.: ::: :::...: :...: :::.::::::.:.. NP_001 MASLGHILVFCVGLLTMAKAESPKEHDPFTYDYQSLQIGGLVIAGILFILGILIVLSRRC 10 20 30 40 50 60 50 60 70 80 pF1KB0 KCR-KADSRSESPTCKSCKSELPSSAPGGGGV .:. . ..:. : NP_001 RCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR 70 80 90 >>NP_068702 (OMIM: 602359) phospholemman precursor [Homo (92 aa) initn: 153 init1: 153 opt: 176 Z-score: 245.8 bits: 49.9 E(85289): 5.9e-07 Smith-Waterman score: 176; 43.1% identity (81.0% similar) in 58 aa overlap (5-61:16-73) 10 20 30 40 pF1KB0 MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKKV :.. ...:.: ::: :::...: :...: :::.::::::.:.. NP_068 MASLGHILVFCVGLLTMAKAESPKEHDPFTYDYQSLQIGGLVIAGILFILGILIVLSRRC 10 20 30 40 50 60 50 60 70 80 pF1KB0 KCR-KADSRSESPTCKSCKSELPSSAPGGGGV .:. . ..:. : NP_068 RCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR 70 80 90 >>XP_016882364 (OMIM: 602359) PREDICTED: phospholemman i (110 aa) initn: 153 init1: 153 opt: 176 Z-score: 244.8 bits: 50.0 E(85289): 6.8e-07 Smith-Waterman score: 176; 43.1% identity (81.0% similar) in 58 aa overlap (5-61:34-91) 10 20 30 pF1KB0 MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLAT :.. ...:.: ::: :::...: :...: XP_016 SKGTHCLIRGVPPRTMASLGHILVFCVGLLTMAKAESPKEHDPFTYDYQSLQIGGLVIAG 10 20 30 40 50 60 40 50 60 70 80 pF1KB0 ILFLLGILIVISKKVKCR-KADSRSESPTCKSCKSELPSSAPGGGGV :::.::::::.:.. .:. . ..:. : XP_016 ILFILGILIVLSRRCRCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR 70 80 90 100 110 >>XP_016882365 (OMIM: 602359) PREDICTED: phospholemman i (110 aa) initn: 153 init1: 153 opt: 176 Z-score: 244.8 bits: 50.0 E(85289): 6.8e-07 Smith-Waterman score: 176; 43.1% identity (81.0% similar) in 58 aa overlap (5-61:34-91) 10 20 30 pF1KB0 MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLAT :.. ...:.: ::: :::...: :...: XP_016 SKGTHCLIRGVPPRTMASLGHILVFCVGLLTMAKAESPKEHDPFTYDYQSLQIGGLVIAG 10 20 30 40 50 60 40 50 60 70 80 pF1KB0 ILFLLGILIVISKKVKCR-KADSRSESPTCKSCKSELPSSAPGGGGV :::.::::::.:.. .:. . ..:. : XP_016 ILFILGILIVLSRRCRCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR 70 80 90 100 110 >>NP_071286 (OMIM: 606683) FXYD domain-containing ion tr (95 aa) initn: 154 init1: 145 opt: 145 Z-score: 204.1 bits: 42.2 E(85289): 0.00013 Smith-Waterman score: 145; 46.2% identity (87.2% similar) in 39 aa overlap (13-51:25-63) 10 20 30 40 pF1KB0 MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKK .: :::.:::.:.. :...:..:: .:::...:.. NP_071 MELVLVFLCSLLAPMVLASAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRR 10 20 30 40 50 60 50 60 70 80 pF1KB0 VKCRKADSRSESPTCKSCKSELPSSAPGGGGV :: NP_071 CKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN 70 80 90 >>NP_001158308 (OMIM: 606683) FXYD domain-containing ion (95 aa) initn: 154 init1: 145 opt: 145 Z-score: 204.1 bits: 42.2 E(85289): 0.00013 Smith-Waterman score: 145; 46.2% identity (87.2% similar) in 39 aa overlap (13-51:25-63) 10 20 30 40 pF1KB0 MATPTQTPTKAPEEPDPFYYDYNTVQTVGMTLATILFLLGILIVISKK .: :::.:::.:.. :...:..:: .:::...:.. NP_001 MELVLVFLCSLLAPMVLASAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRR 10 20 30 40 50 60 50 60 70 80 pF1KB0 VKCRKADSRSESPTCKSCKSELPSSAPGGGGV :: NP_001 CKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN 70 80 90 80 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:54:26 2016 done: Sat Nov 5 17:54:27 2016 Total Scan time: 4.330 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]