FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0904, 299 aa 1>>>pF1KB0904 299 - 299 aa - 299 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4360+/-0.000993; mu= 10.0504+/- 0.059 mean_var=87.0473+/-17.133, 0's: 0 Z-trim(105.6): 22 B-trim: 11 in 1/49 Lambda= 0.137466 statistics sampled from 8497 (8505) to 8497 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.261), width: 16 Scan time: 2.540 The best scores are: opt bits E(32554) CCDS53741.1 PHB2 gene_id:11331|Hs108|chr12 ( 299) 1872 381.2 5.1e-106 CCDS58207.1 PHB2 gene_id:11331|Hs108|chr12 ( 261) 1286 265.0 4.4e-71 CCDS11548.1 PHB gene_id:5245|Hs108|chr17 ( 272) 862 180.9 9.3e-46 CCDS62244.1 PHB gene_id:5245|Hs108|chr17 ( 155) 480 105.0 3.6e-23 >>CCDS53741.1 PHB2 gene_id:11331|Hs108|chr12 (299 aa) initn: 1872 init1: 1872 opt: 1872 Z-score: 2016.8 bits: 381.2 E(32554): 5.1e-106 Smith-Waterman score: 1872; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299) 10 20 30 40 50 60 pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 DTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 DTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 YQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 YQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 DVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 DVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGE 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 ALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK 250 260 270 280 290 >>CCDS58207.1 PHB2 gene_id:11331|Hs108|chr12 (261 aa) initn: 1286 init1: 1286 opt: 1286 Z-score: 1389.7 bits: 265.0 E(32554): 4.4e-71 Smith-Waterman score: 1554; 87.3% identity (87.3% similar) in 299 aa overlap (1-299:1-261) 10 20 30 40 50 60 pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 DTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 YQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 DVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGE ::::::::::::::::::::::: CCDS58 DVAITELSFSREYTAAVEAKQVA------------------------------------- 190 200 250 260 270 280 290 pF1KB0 ALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 -LSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK 210 220 230 240 250 260 >>CCDS11548.1 PHB gene_id:5245|Hs108|chr17 (272 aa) initn: 784 init1: 715 opt: 862 Z-score: 934.9 bits: 180.9 E(32554): 9.3e-46 Smith-Waterman score: 862; 53.9% identity (82.3% similar) in 254 aa overlap (29-280:15-267) 10 20 30 40 50 pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ : ::: :: .: ...:..::::..:.:. ::: CCDS11 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ 10 20 30 40 60 70 80 90 100 110 pF1KB0 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS : ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..:: CCDS11 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB0 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL .. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.::: CCDS11 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB0 DDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLG :::..:.:.:..:.: ::::::::::::.::.:.::::.:... :..:::...::.... CCDS11 DDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB0 EAL-SKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK ..: . . : :.:::..::..:. .. :.: :: : . :: CCDS11 NSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ 230 240 250 260 270 pF1KB0 K >>CCDS62244.1 PHB gene_id:5245|Hs108|chr17 (155 aa) initn: 403 init1: 403 opt: 480 Z-score: 529.4 bits: 105.0 E(32554): 3.6e-23 Smith-Waterman score: 480; 57.8% identity (82.8% similar) in 128 aa overlap (29-155:15-141) 10 20 30 40 50 pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ : ::: :: .: ...:..::::..:.:. ::: CCDS62 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ 10 20 30 40 60 70 80 90 100 110 pF1KB0 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS : ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..:: CCDS62 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB0 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL .. .: ::.:::::::..:.::::::.:.:..::: CCDS62 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITYLPAGQSVLLQLPQ 110 120 130 140 150 180 190 200 210 220 230 pF1KB0 DDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLG 299 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:07:25 2016 done: Sat Nov 5 17:07:25 2016 Total Scan time: 2.540 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]