Result of FASTA (omim) for
pF1KB0904
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0904, 299 aa
1>>>pF1KB0904 299 - 299 aa - 299 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2874+/-0.000441; mu= 11.1543+/- 0.027
mean_var=96.0825+/-18.788, 0's: 0 Z-trim(112.4): 12 B-trim: 267 in 1/51
Lambda= 0.130843
statistics sampled from 21315 (21327) to 21315 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.25), width: 16
Scan time: 7.350
The best scores are: opt bits E(85289)
NP_001138303 (OMIM: 610704) prohibitin-2 isoform 1 ( 299) 1872 363.8 2.4e-100
NP_001254629 (OMIM: 610704) prohibitin-2 isoform 3 ( 261) 1286 253.1 4.2e-67
NP_002625 (OMIM: 114480,176705) prohibitin isoform ( 272) 862 173.1 5.4e-43
NP_001268425 (OMIM: 114480,176705) prohibitin isof ( 272) 862 173.1 5.4e-43
XP_016880252 (OMIM: 114480,176705) PREDICTED: proh ( 272) 862 173.1 5.4e-43
NP_001268644 (OMIM: 114480,176705) prohibitin isof ( 272) 862 173.1 5.4e-43
XP_016880251 (OMIM: 114480,176705) PREDICTED: proh ( 289) 719 146.1 7.6e-35
NP_001268426 (OMIM: 114480,176705) prohibitin isof ( 155) 480 100.8 1.7e-21
>>NP_001138303 (OMIM: 610704) prohibitin-2 isoform 1 [Ho (299 aa)
initn: 1872 init1: 1872 opt: 1872 Z-score: 1922.6 bits: 363.8 E(85289): 2.4e-100
Smith-Waterman score: 1872; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299)
10 20 30 40 50 60
pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 DVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGE
190 200 210 220 230 240
250 260 270 280 290
pF1KB0 ALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK
250 260 270 280 290
>>NP_001254629 (OMIM: 610704) prohibitin-2 isoform 3 [Ho (261 aa)
initn: 1286 init1: 1286 opt: 1286 Z-score: 1325.7 bits: 253.1 E(85289): 4.2e-67
Smith-Waterman score: 1554; 87.3% identity (87.3% similar) in 299 aa overlap (1-299:1-261)
10 20 30 40 50 60
pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 DVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGE
:::::::::::::::::::::::
NP_001 DVAITELSFSREYTAAVEAKQVA-------------------------------------
190 200
250 260 270 280 290
pF1KB0 ALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -LSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK
210 220 230 240 250 260
>>NP_002625 (OMIM: 114480,176705) prohibitin isoform 1 [ (272 aa)
initn: 784 init1: 715 opt: 862 Z-score: 892.9 bits: 173.1 E(85289): 5.4e-43
Smith-Waterman score: 862; 53.9% identity (82.3% similar) in 254 aa overlap (29-280:15-267)
10 20 30 40 50
pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ
: ::: :: .: ...:..::::..:.:. :::
NP_002 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ
10 20 30 40
60 70 80 90 100 110
pF1KB0 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS
: ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..::
NP_002 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB0 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL
.. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.:::
NP_002 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB0 DDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLG
:::..:.:.:..:.: ::::::::::::.::.:.::::.:... :..:::...::....
NP_002 DDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB0 EAL-SKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK
..: . . : :.:::..::..:. .. :.: :: : . ::
NP_002 NSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
230 240 250 260 270
pF1KB0 K
>>NP_001268425 (OMIM: 114480,176705) prohibitin isoform (272 aa)
initn: 784 init1: 715 opt: 862 Z-score: 892.9 bits: 173.1 E(85289): 5.4e-43
Smith-Waterman score: 862; 53.9% identity (82.3% similar) in 254 aa overlap (29-280:15-267)
10 20 30 40 50
pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ
: ::: :: .: ...:..::::..:.:. :::
NP_001 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ
10 20 30 40
60 70 80 90 100 110
pF1KB0 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS
: ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..::
NP_001 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB0 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL
.. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.:::
NP_001 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB0 DDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLG
:::..:.:.:..:.: ::::::::::::.::.:.::::.:... :..:::...::....
NP_001 DDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB0 EAL-SKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK
..: . . : :.:::..::..:. .. :.: :: : . ::
NP_001 NSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
230 240 250 260 270
pF1KB0 K
>>XP_016880252 (OMIM: 114480,176705) PREDICTED: prohibit (272 aa)
initn: 784 init1: 715 opt: 862 Z-score: 892.9 bits: 173.1 E(85289): 5.4e-43
Smith-Waterman score: 862; 53.9% identity (82.3% similar) in 254 aa overlap (29-280:15-267)
10 20 30 40 50
pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ
: ::: :: .: ...:..::::..:.:. :::
XP_016 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ
10 20 30 40
60 70 80 90 100 110
pF1KB0 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS
: ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..::
XP_016 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB0 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL
.. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.:::
XP_016 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB0 DDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLG
:::..:.:.:..:.: ::::::::::::.::.:.::::.:... :..:::...::....
XP_016 DDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB0 EAL-SKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK
..: . . : :.:::..::..:. .. :.: :: : . ::
XP_016 NSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
230 240 250 260 270
pF1KB0 K
>>NP_001268644 (OMIM: 114480,176705) prohibitin isoform (272 aa)
initn: 784 init1: 715 opt: 862 Z-score: 892.9 bits: 173.1 E(85289): 5.4e-43
Smith-Waterman score: 862; 53.9% identity (82.3% similar) in 254 aa overlap (29-280:15-267)
10 20 30 40 50
pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ
: ::: :: .: ...:..::::..:.:. :::
NP_001 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ
10 20 30 40
60 70 80 90 100 110
pF1KB0 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS
: ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..::
NP_001 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB0 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL
.. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.:::
NP_001 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB0 DDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLG
:::..:.:.:..:.: ::::::::::::.::.:.::::.:... :..:::...::....
NP_001 DDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB0 EAL-SKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGK
..: . . : :.:::..::..:. .. :.: :: : . ::
NP_001 NSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
230 240 250 260 270
pF1KB0 K
>>XP_016880251 (OMIM: 114480,176705) PREDICTED: prohibit (289 aa)
initn: 642 init1: 642 opt: 719 Z-score: 746.6 bits: 146.1 E(85289): 7.6e-35
Smith-Waterman score: 719; 59.8% identity (83.6% similar) in 189 aa overlap (29-216:15-202)
10 20 30 40 50
pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ
: ::: :: .: ...:..::::..:.:. :::
XP_016 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ
10 20 30 40
60 70 80 90 100 110
pF1KB0 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS
: ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..::
XP_016 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB0 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL
.. .: ::.:::::::..:.::::::.:.:..::::: :: . .::::: :.:::
XP_016 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLIL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB0 DDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLG
:::..:.:.:..:.: ::::::::::::.::.:.:::
XP_016 DDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKVSLRPDGRSLSLPFLRHSASPFA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB0 EALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK
XP_016 GWPGNSSSVIPSSGIIRRGLKELYFCNWFQSLQGLVKDMWSYVPKSLKGNFSSTSLRSKT
230 240 250 260 270 280
>>NP_001268426 (OMIM: 114480,176705) prohibitin isoform (155 aa)
initn: 403 init1: 403 opt: 480 Z-score: 506.8 bits: 100.8 E(85289): 1.7e-21
Smith-Waterman score: 480; 57.8% identity (82.8% similar) in 128 aa overlap (29-155:15-141)
10 20 30 40 50
pF1KB0 MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRES-VFTVEGGHRAIFFNRIGGVQ
: ::: :: .: ...:..::::..:.:. :::
NP_001 MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQ
10 20 30 40
60 70 80 90 100 110
pF1KB0 QDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPS
: ...:: :: ::: : :::.: :.:::.. ::::::: :::.::.: :: :..::
NP_001 -DIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB0 MYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLIL
.. .: ::.:::::::..:.::::::.:.:..:::
NP_001 IFTSIGEDYDERVLPSITTEILKSVVARFDAGELITYLPAGQSVLLQLPQ
110 120 130 140 150
180 190 200 210 220 230
pF1KB0 DDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLG
299 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:07:25 2016 done: Sat Nov 5 17:07:26 2016
Total Scan time: 7.350 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]