FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0905, 93 aa 1>>>pF1KB0905 93 - 93 aa - 93 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8582+/-0.000278; mu= 11.1162+/- 0.017 mean_var=57.0761+/-11.738, 0's: 0 Z-trim(118.4): 60 B-trim: 597 in 1/54 Lambda= 0.169765 statistics sampled from 31347 (31413) to 31347 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.368), width: 16 Scan time: 3.330 The best scores are: opt bits E(85289) NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 639 163.7 3.8e-41 NP_116738 (OMIM: 601392) C-C motif chemokine 14 is ( 109) 483 125.6 1.4e-29 NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 323 86.3 7.5e-18 NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 323 86.3 7.5e-18 NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 318 85.1 1.7e-17 NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 311 83.4 5.7e-17 NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 307 82.4 1.1e-16 NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 271 73.6 4.9e-14 NP_001278397 (OMIM: 610757) C-C motif chemokine 4- ( 87) 268 72.9 8.1e-14 NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 248 68.0 2.5e-12 NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 246 67.6 4.4e-12 XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 246 67.6 4.4e-12 NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 236 65.1 2e-11 NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 236 65.1 2.7e-11 NP_665905 (OMIM: 602494) C-C motif chemokine 23 is ( 120) 230 63.6 6.7e-11 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 220 61.1 3.1e-10 NP_116741 (OMIM: 601393) C-C motif chemokine 15 pr ( 113) 220 61.2 3.5e-10 XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 219 60.9 3.5e-10 NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 219 60.9 3.5e-10 XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 219 61.0 5.1e-10 NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 214 59.7 8.6e-10 NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 212 59.2 1.2e-09 NP_001278401 (OMIM: 610757) C-C motif chemokine 4- ( 96) 204 57.2 4.6e-09 XP_011521558 (OMIM: 601520) PREDICTED: C-C motif c ( 122) 202 56.8 7.8e-09 XP_016879019 (OMIM: 601520) PREDICTED: C-C motif c ( 123) 202 56.8 7.9e-09 NP_002978 (OMIM: 601520) C-C motif chemokine 17 pr ( 94) 200 56.2 8.9e-09 XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 201 56.5 9.1e-09 NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 201 56.5 9.1e-09 XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 201 56.5 9.1e-09 NP_001278400 (OMIM: 610757) C-C motif chemokine 4- ( 103) 192 54.3 3.7e-08 NP_001278404 (OMIM: 610757) C-C motif chemokine 4- ( 103) 191 54.0 4.4e-08 NP_001278398 (OMIM: 610757) C-C motif chemokine 4- ( 64) 188 53.2 5e-08 NP_001278399 (OMIM: 610757) C-C motif chemokine 4- ( 64) 188 53.2 5e-08 NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 189 53.5 6e-08 NP_001278402 (OMIM: 610757) C-C motif chemokine 4- ( 86) 188 53.3 6.3e-08 XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 186 52.8 9.5e-08 NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 186 52.8 9.5e-08 NP_002972 (OMIM: 182281) C-C motif chemokine 1 pre ( 96) 171 49.1 1.2e-06 NP_001265665 (OMIM: 187011) C-C motif chemokine 5 ( 154) 158 46.1 1.7e-05 NP_003166 (OMIM: 604828) cytokine SCM-1 beta precu ( 114) 155 45.3 2.2e-05 NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 154 45.0 2.9e-05 XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 154 45.1 3.1e-05 XP_011508167 (OMIM: 600250) PREDICTED: lymphotacti ( 114) 152 44.5 3.6e-05 NP_002986 (OMIM: 600250) lymphotactin precursor [H ( 114) 152 44.5 3.6e-05 NP_006265 (OMIM: 602227) C-C motif chemokine 19 pr ( 98) 141 41.8 0.00021 NP_001123518 (OMIM: 601960) C-C motif chemokine 20 ( 95) 122 37.1 0.005 NP_004582 (OMIM: 601960) C-C motif chemokine 20 is ( 96) 122 37.1 0.0051 NP_002987 (OMIM: 601880) fractalkine isoform 1 pre ( 397) 127 38.7 0.007 >>NP_116739 (OMIM: 601392) C-C motif chemokine 14 isofor (93 aa) initn: 639 init1: 639 opt: 639 Z-score: 859.7 bits: 163.7 E(85289): 3.8e-41 Smith-Waterman score: 639; 100.0% identity (100.0% similar) in 93 aa overlap (1-93:1-93) 10 20 30 40 50 60 pF1KB0 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS 10 20 30 40 50 60 70 80 90 pF1KB0 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN ::::::::::::::::::::::::::::::::: NP_116 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN 70 80 90 >>NP_116738 (OMIM: 601392) C-C motif chemokine 14 isofor (109 aa) initn: 619 init1: 483 opt: 483 Z-score: 652.2 bits: 125.6 E(85289): 1.4e-29 Smith-Waterman score: 591; 84.4% identity (85.3% similar) in 109 aa overlap (1-93:1-109) 10 20 30 40 pF1KB0 MKISVAAIPFFLLITIALGTKTESSSR----------------GPYHPSECCFTYTTYKI ::::::::::::::::::::::::::. ::::::::::::::::: NP_116 MKISVAAIPFFLLITIALGTKTESSSQTGGKPKVVKIQLKLVGGPYHPSECCFTYTTYKI 10 20 30 40 50 60 50 60 70 80 90 pF1KB0 PRQRIMDYYETNSQCSKPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN ::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 PRQRIMDYYETNSQCSKPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN 70 80 90 100 >>NP_001001437 (OMIM: 609468) C-C motif chemokine 3-like (93 aa) initn: 325 init1: 307 opt: 323 Z-score: 441.5 bits: 86.3 E(85289): 7.5e-18 Smith-Waterman score: 323; 47.3% identity (82.4% similar) in 91 aa overlap (1-91:1-90) 10 20 30 40 50 60 pF1KB0 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS :..:.::. :: :.:: ... :. . :. :::.::. .::.. : ::.::.:::: NP_001 MQVSTAALAV-LLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCS 10 20 30 40 50 70 80 90 pF1KB0 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN ::...:.::::..::..::..::: :..:.. NP_001 KPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 >>NP_066286 (OMIM: 601395,609423) C-C motif chemokine 3- (93 aa) initn: 325 init1: 307 opt: 323 Z-score: 441.5 bits: 86.3 E(85289): 7.5e-18 Smith-Waterman score: 323; 47.3% identity (82.4% similar) in 91 aa overlap (1-91:1-90) 10 20 30 40 50 60 pF1KB0 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS :..:.::. :: :.:: ... :. . :. :::.::. .::.. : ::.::.:::: NP_066 MQVSTAALAV-LLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCS 10 20 30 40 50 70 80 90 pF1KB0 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN ::...:.::::..::..::..::: :..:.. NP_066 KPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 >>NP_002974 (OMIM: 182283,609423) C-C motif chemokine 3 (92 aa) initn: 299 init1: 279 opt: 318 Z-score: 434.9 bits: 85.1 E(85289): 1.7e-17 Smith-Waterman score: 318; 48.4% identity (82.4% similar) in 91 aa overlap (1-91:1-89) 10 20 30 40 50 60 pF1KB0 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS :..:.::. :: :.:: .. :.: . :. :::.::. .::.. : ::.::.:::: NP_002 MQVSTAALAV-LLCTMALCNQF-SASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCS 10 20 30 40 50 70 80 90 pF1KB0 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN :::..:.:::...::..::..::: :..:.. NP_002 KPGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 >>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa) initn: 301 init1: 276 opt: 311 Z-score: 425.7 bits: 83.4 E(85289): 5.7e-17 Smith-Waterman score: 311; 44.1% identity (80.6% similar) in 93 aa overlap (1-93:1-92) 10 20 30 40 50 60 pF1KB0 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS ::. :... ...:.. :. . . :. : :. :::.::. :.::. ..:::::.: :: NP_996 MKLCVTVLSLLVLVA-AFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCS 10 20 30 40 50 70 80 90 pF1KB0 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN .:..:: ::::..::..::..:::.:. :.. : NP_996 QPAVVFQTKRGKQVCADPSESWVQEYVYDLELN 60 70 80 90 >>NP_002975 (OMIM: 182284) C-C motif chemokine 4 precurs (92 aa) initn: 295 init1: 268 opt: 307 Z-score: 420.4 bits: 82.4 E(85289): 1.1e-16 Smith-Waterman score: 307; 43.0% identity (80.6% similar) in 93 aa overlap (1-93:1-92) 10 20 30 40 50 60 pF1KB0 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS ::. :... ...:.. :. . . :. : :. :::.::. :.::. ..:::::.: :: NP_002 MKLCVTVLSLLMLVA-AFCSPALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCS 10 20 30 40 50 70 80 90 pF1KB0 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN .:..:: :::...::..::..:::.:. :.. : NP_002 QPAVVFQTKRSKQVCADPSESWVQEYVYDLELN 60 70 80 90 >>NP_002979 (OMIM: 603757) C-C motif chemokine 18 precur (89 aa) initn: 290 init1: 267 opt: 271 Z-score: 372.9 bits: 73.6 E(85289): 4.9e-14 Smith-Waterman score: 271; 41.9% identity (76.3% similar) in 93 aa overlap (1-93:1-88) 10 20 30 40 50 60 pF1KB0 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS :: ..:: . :. :.:: . .. .. . ::..::...::.. :.:: ::. :: NP_002 MK-GLAAALLVLVCTMALCSCAQVGT----NKELCCLVYTSWQIPQKFIVDYSETSPQCP 10 20 30 40 50 70 80 90 pF1KB0 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN :::....::::...:..:. :::: ::.:.: : NP_002 KPGVILLTKRGRQICADPNKKWVQKYISDLKLNA 60 70 80 >>NP_001278397 (OMIM: 610757) C-C motif chemokine 4-like (87 aa) initn: 249 init1: 153 opt: 268 Z-score: 369.1 bits: 72.9 E(85289): 8.1e-14 Smith-Waterman score: 268; 39.8% identity (76.3% similar) in 93 aa overlap (1-93:1-87) 10 20 30 40 50 60 pF1KB0 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS ::. :... ...:.. :. . . :. : :. :::.::. :.::. ..:::::.: :: NP_001 MKLCVTVLSLLVLVA-AFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCS 10 20 30 40 50 70 80 90 pF1KB0 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN .:..: :..::..::..:::.:. :.. : NP_001 QPAVV-----GKQVCADPSESWVQEYVYDLELN 60 70 80 >>NP_002976 (OMIM: 187011) C-C motif chemokine 5 isoform (91 aa) initn: 256 init1: 219 opt: 248 Z-score: 342.3 bits: 68.0 E(85289): 2.5e-12 Smith-Waterman score: 248; 38.7% identity (74.2% similar) in 93 aa overlap (1-91:1-89) 10 20 30 40 50 pF1KB0 MKISVAAIPFFLLITIALGTKTESSSRGPYHP--SECCFTYTTYKIPRQRIMDYYETNSQ ::.:.::. .::. :: .: .:: . :::.: . .:: .: .:. :... NP_002 MKVSAAALAV-ILIATAL---CAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGK 10 20 30 40 50 60 70 80 90 pF1KB0 CSKPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN ::.:..::.:.....::.:: :::..::.... NP_002 CSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS 60 70 80 90 93 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:07:52 2016 done: Sat Nov 5 17:07:53 2016 Total Scan time: 3.330 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]