Result of FASTA (omim) for
pF1KB0916
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0916, 328 aa
1>>>pF1KB0916 328 - 328 aa - 328 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1329+/-0.000259; mu= 14.4026+/- 0.016
mean_var=120.1594+/-24.285, 0's: 0 Z-trim(122.7): 59 B-trim: 13 in 1/56
Lambda= 0.117003
statistics sampled from 41195 (41255) to 41195 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.484), width: 16
Scan time: 9.340
The best scores are: opt bits E(85289)
NP_001272916 (OMIM: 164177) POU domain, class 5, t ( 265) 681 125.0 1.7e-28
NP_002692 (OMIM: 164177) POU domain, class 5, tran ( 360) 680 125.0 2.4e-28
NP_001153014 (OMIM: 615739) putative POU domain, c ( 359) 655 120.8 4.4e-27
NP_976034 (OMIM: 164177) POU domain, class 5, tran ( 190) 536 100.4 3.1e-21
NP_001167002 (OMIM: 164177) POU domain, class 5, t ( 190) 536 100.4 3.1e-21
NP_000298 (OMIM: 300039,304400) POU domain, class ( 361) 490 92.9 1.1e-18
NP_002690 (OMIM: 602479) POU domain, class 3, tran ( 451) 488 92.7 1.6e-18
NP_006227 (OMIM: 602480) POU domain, class 3, tran ( 500) 482 91.7 3.5e-18
NP_005595 (OMIM: 600494) POU domain, class 3, tran ( 443) 476 90.6 6.4e-18
XP_011541043 (OMIM: 607394) PREDICTED: POU domain, ( 403) 429 82.7 1.5e-15
XP_011541044 (OMIM: 607394) PREDICTED: POU domain, ( 403) 429 82.7 1.5e-15
XP_011541045 (OMIM: 607394) PREDICTED: POU domain, ( 403) 429 82.7 1.5e-15
XP_011541041 (OMIM: 607394) PREDICTED: POU domain, ( 432) 429 82.7 1.5e-15
XP_011541042 (OMIM: 607394) PREDICTED: POU domain, ( 432) 429 82.7 1.5e-15
NP_055167 (OMIM: 607394) POU domain, class 2, tran ( 436) 429 82.7 1.6e-15
NP_001231611 (OMIM: 607394) POU domain, class 2, t ( 438) 429 82.7 1.6e-15
XP_016872976 (OMIM: 607394) PREDICTED: POU domain, ( 356) 418 80.8 4.9e-15
NP_001272915 (OMIM: 164177) POU domain, class 5, t ( 164) 408 78.8 9e-15
XP_011507957 (OMIM: 164175) PREDICTED: POU domain, ( 671) 400 78.0 6.3e-14
NP_001185715 (OMIM: 164175) POU domain, class 2, t ( 703) 400 78.0 6.5e-14
XP_011507956 (OMIM: 164175) PREDICTED: POU domain, ( 743) 400 78.0 6.8e-14
NP_001185712 (OMIM: 164175) POU domain, class 2, t ( 755) 400 78.0 6.9e-14
NP_002688 (OMIM: 164175) POU domain, class 2, tran ( 766) 400 78.0 6.9e-14
XP_011507955 (OMIM: 164175) PREDICTED: POU domain, ( 769) 400 78.0 7e-14
NP_000297 (OMIM: 173110,613038) pituitary-specific ( 291) 354 69.9 7.5e-12
NP_001116229 (OMIM: 173110,613038) pituitary-speci ( 317) 354 69.9 8e-12
NP_001193955 (OMIM: 164176) POU domain, class 2, t ( 467) 352 69.7 1.3e-11
NP_001193954 (OMIM: 164176) POU domain, class 2, t ( 479) 352 69.7 1.4e-11
XP_011525343 (OMIM: 164176) PREDICTED: POU domain, ( 501) 352 69.8 1.4e-11
XP_011525345 (OMIM: 164176) PREDICTED: POU domain, ( 537) 352 69.8 1.5e-11
XP_016882385 (OMIM: 164176) PREDICTED: POU domain, ( 600) 352 69.8 1.6e-11
XP_016882383 (OMIM: 164176) PREDICTED: POU domain, ( 602) 352 69.8 1.6e-11
XP_016882384 (OMIM: 164176) PREDICTED: POU domain, ( 602) 352 69.8 1.6e-11
XP_011525342 (OMIM: 164176) PREDICTED: POU domain, ( 624) 352 69.8 1.6e-11
XP_016882381 (OMIM: 164176) PREDICTED: POU domain, ( 701) 352 69.9 1.8e-11
XP_016882377 (OMIM: 164176) PREDICTED: POU domain, ( 711) 352 69.9 1.8e-11
XP_016882379 (OMIM: 164176) PREDICTED: POU domain, ( 711) 352 69.9 1.8e-11
XP_016882376 (OMIM: 164176) PREDICTED: POU domain, ( 711) 352 69.9 1.8e-11
XP_016882375 (OMIM: 164176) PREDICTED: POU domain, ( 711) 352 69.9 1.8e-11
XP_016882378 (OMIM: 164176) PREDICTED: POU domain, ( 711) 352 69.9 1.8e-11
XP_016882373 (OMIM: 164176) PREDICTED: POU domain, ( 723) 352 69.9 1.8e-11
XP_016882374 (OMIM: 164176) PREDICTED: POU domain, ( 723) 352 69.9 1.8e-11
NP_006228 (OMIM: 601632) POU domain, class 4, tran ( 419) 347 68.8 2.2e-11
NP_004566 (OMIM: 113725) POU domain, class 4, tran ( 409) 338 67.3 6.2e-11
NP_002691 (OMIM: 602459,602460) POU domain, class ( 338) 336 66.9 6.9e-11
NP_001159490 (OMIM: 601583,609062) POU domain, cla ( 655) 315 63.6 1.3e-09
NP_001234923 (OMIM: 164176) POU domain, class 2, t ( 400) 288 58.9 2.1e-08
NP_002689 (OMIM: 164176) POU domain, class 2, tran ( 463) 288 58.9 2.4e-08
XP_011525344 (OMIM: 164176) PREDICTED: POU domain, ( 485) 288 58.9 2.5e-08
XP_005259067 (OMIM: 164176) PREDICTED: POU domain, ( 586) 288 59.0 2.8e-08
>>NP_001272916 (OMIM: 164177) POU domain, class 5, trans (265 aa)
initn: 707 init1: 626 opt: 681 Z-score: 632.6 bits: 125.0 E(85289): 1.7e-28
Smith-Waterman score: 690; 50.9% identity (71.1% similar) in 232 aa overlap (104-324:29-259)
80 90 100 110 120 130
pF1KB0 GWIAPCRPRLGASEAGDWLRRPSEGALPGPYIALRSIPKLPPPEDISGILKELQQLAKEL
:. .: .::... :::.:.:: :
NP_001 MHFYRLFLGATRRFLNPEWKGEIDNWCVYVLTSLLPFKIQSQDIKALQKELEQFAKLL
10 20 30 40 50
140 150 160 170 180 190
pF1KB0 RQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVEA
.:::..:::.:::::...:.:::::.:::::::::: ::: :: ::::::.::..:..
NP_001 KQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADN
60 70 80 90 100 110
200 210 220 230 240 250
pF1KB0 -ENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKD
::: .:: : ..: : .:.: : :. ..::..: .::::: ::::::: : :.::
NP_001 NENLQEICKAETLVQAR-KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKD
120 130 140 150 160 170
260 270 280 290 300
pF1KB0 VVRVWFYNRSKMGSRPTNDASPREIVGTAGPPCPGAPVCFHLG----LGLP-VDIPHYTR
:::::: :: . :.: ..: . :: .:: : :.:: : :. .: : ::.:
NP_001 VVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTA
180 190 200 210 220 230
310 320
pF1KB0 LYSA-----GVAHSSAPATTLGLLRF
:::. : : . .::::
NP_001 LYSSVPFPEGEAFPPVSVTTLGSPMHSN
240 250 260
>>NP_002692 (OMIM: 164177) POU domain, class 5, transcri (360 aa)
initn: 925 init1: 619 opt: 680 Z-score: 629.9 bits: 125.0 E(85289): 2.4e-28
Smith-Waterman score: 945; 47.6% identity (64.9% similar) in 359 aa overlap (1-324:1-354)
10 20 30 40 50
pF1KB0 MAGHRPSNH-FCPLPGSGGGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPD
:::: :. : : ::.:: :: :: : :: :::: :. :: :.. ::. :: .
NP_002 MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGG----PGIGPGVGPGSE
10 20 30 40 50
60 70 80 90 100
pF1KB0 VWRIPLGPLPHEFRGWIAPCRPRLGAS--------------EAGDWLRRPSEGALPGPYI
:: :: : :.:: : .: : :..:.. ::: .. :.:: : :
NP_002 VWGIPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCT
60 70 80 90 100 110
110 120 130 140 150
pF1KB0 ALRSIPKLPP------PE---DISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFG
. . :: :: ::... :::.:.:: :.:::..:::.:::::...:.:::
NP_002 VTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB0 KVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVEA-ENLLGLCKMEMILQQSGKWRRA
::.:::::::::: ::: :: ::::::.::..:.. ::: .:: : ..: : .:.
NP_002 KVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQAR-KRKRT
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB0 SRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPR
: : :. ..::..: .::::: ::::::: : :.:::::::: :: . :.: ..: . :
NP_002 SIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQR
240 250 260 270 280 290
280 290 300 310 320
pF1KB0 EIVGTAGPPCPGAPVCFHLG----LGLP-VDIPHYTRLYSA-----GVAHSSAPATTLGL
: .:: : :.:: : :. .: : ::.: :::. : : . .::::
NP_002 EDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGS
300 310 320 330 340 350
pF1KB0 LRF
NP_002 PMHSN
360
>>NP_001153014 (OMIM: 615739) putative POU domain, class (359 aa)
initn: 775 init1: 422 opt: 655 Z-score: 607.1 bits: 120.8 E(85289): 4.4e-27
Smith-Waterman score: 895; 47.8% identity (65.1% similar) in 341 aa overlap (1-311:1-335)
10 20 30 40 50
pF1KB0 MAGHRPSNH-FCPLPGSGGGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPD
:::: :. : : ::.:: :: : : :: ::::: :. :: :.. ::. :: .
NP_001 MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGG----PGIGPGVGPGSE
10 20 30 40 50
60 70 80 90 100
pF1KB0 VWRIPLGPLPHEFRGWIAPCRPRLGA--------------SEAGDWLRRPSEGALPGPYI
:: :: : :.:. : .: : :..:. :::: .. :.:: : :
NP_001 VWGIPPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCT
60 70 80 90 100 110
110 120 130 140 150
pF1KB0 ALRSIPKLPP------PE---DISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFG
. . :: :: ::... :::.:.:: :.:::..:::.:::::. .:.:::
NP_001 VPPGAVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB0 KVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVEA-ENLLGLCKMEMILQQSGKWRRA
::.:: ::::::: ::: :: ::::::.::..:.. ::: .:: : :.:. : .:.
NP_001 KVFSQKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAET-LMQARKRKRT
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB0 SRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPR
: : :. ..::..: .::::: :::::: : :.:::::::: :: . :.: ..: . :
NP_001 SIENRVRGNLENLFLQCPKPT-LQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQR
240 250 260 270 280 290
280 290 300 310 320
pF1KB0 EIVGTAGPPCPGAPVCFHLG----LGLP-VDIPHYTRLYSAGVAHSSAPATTLGLLRF
: .:: : :.:: : . .: : ::.: :::.
NP_001 EDFEAAGSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGS
300 310 320 330 340 350
NP_001 PMHSN
>>NP_976034 (OMIM: 164177) POU domain, class 5, transcri (190 aa)
initn: 553 init1: 472 opt: 536 Z-score: 502.1 bits: 100.4 E(85289): 3.1e-21
Smith-Waterman score: 545; 51.9% identity (69.7% similar) in 185 aa overlap (151-324:1-184)
130 140 150 160 170 180
pF1KB0 GILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKL
.:.:::::.:::::::::: ::: :: ::
NP_976 MGVLFGKVFSQTTICRFEALQLSFKNMCKL
10 20 30
190 200 210 220 230
pF1KB0 RPLLKKWLKEVEA-ENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQ
::::.::..:.. ::: .:: : ..: : .:.: : :. ..::..: .::::: ::
NP_976 RPLLQKWVEEADNNENLQEICKAETLVQAR-KRKRTSIENRVRGNLENLFLQCPKPTLQQ
40 50 60 70 80
240 250 260 270 280 290
pF1KB0 ISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAGPPCPGAPVCFHLG----
::::: : :.:::::::: :: . :.: ..: . :: .:: : :.:: : :.
NP_976 ISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPH
90 100 110 120 130 140
300 310 320
pF1KB0 LGLP-VDIPHYTRLYSA-----GVAHSSAPATTLGLLRF
.: : ::.: :::. : : . .::::
NP_976 FGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
150 160 170 180 190
>>NP_001167002 (OMIM: 164177) POU domain, class 5, trans (190 aa)
initn: 553 init1: 472 opt: 536 Z-score: 502.1 bits: 100.4 E(85289): 3.1e-21
Smith-Waterman score: 545; 51.9% identity (69.7% similar) in 185 aa overlap (151-324:1-184)
130 140 150 160 170 180
pF1KB0 GILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKL
.:.:::::.:::::::::: ::: :: ::
NP_001 MGVLFGKVFSQTTICRFEALQLSFKNMCKL
10 20 30
190 200 210 220 230
pF1KB0 RPLLKKWLKEVEA-ENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQ
::::.::..:.. ::: .:: : ..: : .:.: : :. ..::..: .::::: ::
NP_001 RPLLQKWVEEADNNENLQEICKAETLVQAR-KRKRTSIENRVRGNLENLFLQCPKPTLQQ
40 50 60 70 80
240 250 260 270 280 290
pF1KB0 ISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAGPPCPGAPVCFHLG----
::::: : :.:::::::: :: . :.: ..: . :: .:: : :.:: : :.
NP_001 ISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPH
90 100 110 120 130 140
300 310 320
pF1KB0 LGLP-VDIPHYTRLYSA-----GVAHSSAPATTLGLLRF
.: : ::.: :::. : : . .::::
NP_001 FGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
150 160 170 180 190
>>NP_000298 (OMIM: 300039,304400) POU domain, class 3, t (361 aa)
initn: 465 init1: 465 opt: 490 Z-score: 456.6 bits: 92.9 E(85289): 1.1e-18
Smith-Waterman score: 495; 39.3% identity (62.3% similar) in 239 aa overlap (48-277:118-347)
20 30 40 50 60 70
pF1KB0 GGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPG--P-DVWRIP----LGPLPH
:: :.: . : .:. : : : :
NP_000 LQLGAIIHHRSPHVAHHSPHTNHPNAWGASPAPNPSITSSGQPLNVYSQPGFTVSGMLEH
90 100 110 120 130 140
80 90 100 110 120 130
pF1KB0 EFRGWIAPCRPRLGASEAGDWLRRPSEGALPGPYIALRSIPKLPPPEDISGILKELQQLA
: ..: .:. ::.: . . : . . : : ::.:.:
NP_000 ---GGLTPPPAAASAQSLHPVLREPPDHGELGSHHCQDHSDEETPTSD------ELEQFA
150 160 170 180 190
140 150 160 170 180 190
pF1KB0 KELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKE
:...:.:..::..:::::.:.:.:.:.:.:::::::::: ::: :: ::.:::.:::.:
NP_000 KQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEE
200 210 220 230 240 250
200 210 220 230 240 250
pF1KB0 VEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQ
... . .. : . .:.: : . . :: : .::::. :.:: .: :::.
NP_000 ADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLE
260 270 280 290 300 310
260 270 280 290 300
pF1KB0 KDVVRVWFYNRSKMGSR--PTNDASPREIVGTAGPPCPGAPVCFHLGLGLPVDIPHYTRL
:.:::::: :: . .: : .: .:.:.
NP_000 KEVVRVWFCNRRQKEKRMTPPGDQQPHEVYSHTVKTDTSCHDL
320 330 340 350 360
>>NP_002690 (OMIM: 602479) POU domain, class 3, transcri (451 aa)
initn: 475 init1: 438 opt: 488 Z-score: 453.5 bits: 92.7 E(85289): 1.6e-18
Smith-Waterman score: 493; 34.0% identity (57.8% similar) in 315 aa overlap (4-293:135-439)
10 20 30
pF1KB0 MAGHRPSNHFCPLPGSGGGGPRGPMPLRVDTLT
:. . . : ::..:: . :.:: . . .
NP_002 DGGGGGGFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGG--HQPQPLGLYAQA
110 120 130 140 150 160
40 50 60 70 80
pF1KB0 WLSTQAAPGRVMVWPAVRPGICPG------PDVWRIPLGPLPHEFRGWI--APCRPRLGA
.. : . . : : :: : . : : : : : . . :.
NP_002 AYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGG
170 180 190 200 210 220
90 100 110 120 130 140
pF1KB0 SEAGDWLRRPSEGALPGPYIALRSIPKLPPPEDISGILKELQQLAKELRQKRLSLGYSQA
.:. .:. :. : .. .: : .: :.:.::...:.:..::..::
NP_002 LHAAAAHLHPGAGG-GGSSVGEHSDEDAPSSDD-------LEQFAKQFKQRRIKLGFTQA
230 240 250 260 270
150 160 170 180 190 200
pF1KB0 DVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVEAENLLGLCKMEMI
:::.:.:.:.:.:.:::::::::: ::: :: ::.:::.:::.:... . ..
NP_002 DVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIA
280 290 300 310 320 330
210 220 230 240 250 260
pF1KB0 LQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSK--
: . .:.: : . ..::. : .::::. ..:. .: :::.:.:::::: :: .
NP_002 AQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKE
340 350 360 370 380 390
270 280 290 300
pF1KB0 --------MGSRPTNDA-SPREIV---GTAGPPC---PGAPVCFHLGLGLPVDIPHYTRL
: : .:. .: :. : :.:: : :. .:
NP_002 KRMTPAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAALHHHHHHTLPGSVQ
400 410 420 430 440 450
310 320
pF1KB0 YSAGVAHSSAPATTLGLLRF
>>NP_006227 (OMIM: 602480) POU domain, class 3, transcri (500 aa)
initn: 548 init1: 449 opt: 482 Z-score: 447.5 bits: 91.7 E(85289): 3.5e-18
Smith-Waterman score: 485; 38.6% identity (63.9% similar) in 241 aa overlap (64-300:280-499)
40 50 60 70 80 90
pF1KB0 WLSTQAAPGRVMVWPAVRPGICPGPDVWRIPLGPLPHEFRGWIAPCRPRLGASEAGDWLR
: : ::. .: : :. :.. .:
NP_006 GAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQG---P--PHHGGG-GG----
250 260 270 280 290
100 110 120 130 140 150
pF1KB0 RPSEGALPGPYIALRSIPKLPPPEDISGILKELQQLAKELRQKRLSLGYSQADVGIAVGA
:: :: : : . : .. . .:.:.::...:.:..::..:::::.:.:.
NP_006 ----GAGPG----LNS--HDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGT
300 310 320 330 340
160 170 180 190 200 210
pF1KB0 LFGKVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVEAENLLGLCKMEMILQQSGKWR
:.:.:.:::::::::: ::: :: ::.:::.:::.:... . .. : . .
NP_006 LYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKK
350 360 370 380 390 400
220 230 240 250 260
pF1KB0 RASRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPT----
:.: : . ..::. : .::::. :.:...: :::.:.:::::: :: . .: :
NP_006 RTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGI
410 420 430 440 450 460
270 280 290 300 310 320
pF1KB0 NDASPREIVGTAGPPCPGAPVCFHLGLGLPVDIPHYTRLYSAGVAHSSAPATTLGLLRF
.. .: .. . .: .: : :: :
NP_006 QQQTPDDVYSQVGTVSADTPPPHH-GLQTSVQ
470 480 490 500
>>NP_005595 (OMIM: 600494) POU domain, class 3, transcri (443 aa)
initn: 544 init1: 448 opt: 476 Z-score: 442.7 bits: 90.6 E(85289): 6.4e-18
Smith-Waterman score: 476; 42.2% identity (70.3% similar) in 185 aa overlap (114-290:258-442)
90 100 110 120 130 140
pF1KB0 GASEAGDWLRRPSEGALPGPYIALRSIPKLPPPEDISGILKELQQLAKELRQKRLSLGYS
: .. . .:.:.::...:.:..::..
NP_005 HPHPHSHPHQQPPPPPPPQGPPGHPGAHHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFT
230 240 250 260 270 280
150 160 170 180 190 200
pF1KB0 QADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVEAENLLGLCKME
:::::.:.:.:.:.:.:::::::::: ::: :: ::.:::.:::.:... . .
NP_005 QADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSSGSPTSIDK
290 300 310 320 330 340
210 220 230 240 250 260
pF1KB0 MILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSK
. : . .:.: : . ..::. : .::::. :.:. .: :::.:.:::::: :: .
NP_005 IAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQ
350 360 370 380 390 400
270 280 290 300 310
pF1KB0 MGSR--PTNDASP--REIVGTA--GPPCPGA--PVCFHLGLGLPVDIPHYTRLYSAGVAH
.: : . . : ... : . :: :. ::
NP_005 KEKRMTPPGGTLPGAEDVYGGSRDTPPHHGVQTPVQ
410 420 430 440
320
pF1KB0 SSAPATTLGLLRF
>>XP_011541043 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 424 init1: 268 opt: 429 Z-score: 400.3 bits: 82.7 E(85289): 1.5e-15
Smith-Waterman score: 434; 34.3% identity (60.7% similar) in 280 aa overlap (56-319:84-352)
30 40 50 60 70 80
pF1KB0 PLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPDVWRIPLGPLPHEFRGWIAPCRPRLGA
:: . . : :.:.. : . : . :
XP_011 DMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQSGLLLP---QTGP
60 70 80 90 100 110
90 100 110 120 130
pF1KB0 SEAGDWLRRPSEGALPGPYIA--LRSIPKLPPPEDI--SGI------LKELQQLAKELRQ
. :.. . .:. ::: . :.. .:: :. . :: :.::...:: ..:
XP_011 GLASQAFGHPG---LPGSSLEPHLEASQHLPVPKHLPSSGGADEPSDLEELEKFAKTFKQ
120 130 140 150 160
140 150 160 170 180 190
pF1KB0 KRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVEAE-
.:..::..:.:::.:.: :.:. .::::: :::: .:: :: ::.:::.:::...:.
XP_011 RRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSP
170 180 190 200 210 220
200 210 220 230 240
pF1KB0 ---NLLGLCKMEMILQQSGKWR--RASRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQL
.. .. . . :. : :.: : : .::: :: :::. ..:: :: :..
XP_011 SDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSM
230 240 250 260 270 280
250 260 270 280 290 300
pF1KB0 QKDVVRVWFYNRSKMGSRPTNDASPREIVGTAGPPCPGAPVCFHLGLGLPVDIPHYTRLY
.:.:::::: :: . .: . : .. :: .. . : :...: .
XP_011 EKEVVRVWFCNRRQKEKRIN---CP--VATPIKPPVYNSRLVSPSGSLGPLSVPPVHSTM
290 300 310 320 330 340
310 320
pF1KB0 SAGVAHSSAPATTLGLLRF
. :. : .:
XP_011 PGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHSTYL
350 360 370 380 390 400
328 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:56:04 2016 done: Sat Nov 5 17:56:06 2016
Total Scan time: 9.340 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]