FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0918, 331 aa 1>>>pF1KB0918 331 - 331 aa - 331 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1476+/-0.000329; mu= 12.2839+/- 0.020 mean_var=87.8860+/-17.334, 0's: 0 Z-trim(117.7): 99 B-trim: 785 in 1/53 Lambda= 0.136809 statistics sampled from 29765 (29879) to 29765 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.35), width: 16 Scan time: 7.630 The best scores are: opt bits E(85289) NP_001035533 (OMIM: 147050,600807,607796) PHD fing ( 331) 2234 450.6 2.2e-126 NP_001035534 (OMIM: 147050,600807,607796) PHD fing ( 292) 1981 400.6 2.1e-111 NP_115711 (OMIM: 300414,301900) PHD finger protein ( 312) 352 79.1 1.4e-14 NP_001015877 (OMIM: 300414,301900) PHD finger prot ( 365) 311 71.0 4.3e-12 NP_115834 (OMIM: 300414,301900) PHD finger protein ( 365) 311 71.0 4.3e-12 NP_060239 (OMIM: 611299) G2/M phase-specific E3 ub ( 706) 235 56.2 2.4e-07 XP_011535227 (OMIM: 611299) PREDICTED: G2/M phase- ( 706) 235 56.2 2.4e-07 XP_011535228 (OMIM: 611299) PREDICTED: G2/M phase- ( 667) 230 55.2 4.6e-07 XP_006718902 (OMIM: 159555,605130) PREDICTED: hist (3133) 209 51.4 3e-05 XP_011541135 (OMIM: 159555,605130) PREDICTED: hist (3166) 209 51.4 3e-05 NP_005924 (OMIM: 159555,605130) histone-lysine N-m (3969) 209 51.4 3.7e-05 NP_001184033 (OMIM: 159555,605130) histone-lysine (3972) 209 51.4 3.7e-05 XP_011541133 (OMIM: 159555,605130) PREDICTED: hist (4002) 209 51.4 3.7e-05 XP_011541132 (OMIM: 159555,605130) PREDICTED: hist (4004) 209 51.4 3.7e-05 XP_011541131 (OMIM: 159555,605130) PREDICTED: hist (4005) 209 51.4 3.7e-05 NP_001295026 (OMIM: 611299) G2/M phase-specific E3 ( 660) 197 48.7 4.2e-05 XP_016883035 (OMIM: 606834) PREDICTED: histone-lys (1703) 201 49.7 5.4e-05 XP_016883034 (OMIM: 606834) PREDICTED: histone-lys (2527) 201 49.8 7.5e-05 XP_011525863 (OMIM: 606834) PREDICTED: histone-lys (2527) 201 49.8 7.5e-05 XP_011525864 (OMIM: 606834) PREDICTED: histone-lys (2628) 201 49.8 7.7e-05 XP_016883033 (OMIM: 606834) PREDICTED: histone-lys (2685) 201 49.8 7.9e-05 NP_055542 (OMIM: 606834) histone-lysine N-methyltr (2715) 201 49.8 7.9e-05 XP_016867979 (OMIM: 606833) PREDICTED: histone-lys (3741) 172 44.1 0.0055 XP_016867978 (OMIM: 606833) PREDICTED: histone-lys (3873) 172 44.1 0.0057 XP_011514756 (OMIM: 606833) PREDICTED: histone-lys (4678) 172 44.2 0.0066 XP_011514755 (OMIM: 606833) PREDICTED: histone-lys (4904) 172 44.2 0.0069 NP_733751 (OMIM: 606833) histone-lysine N-methyltr (4911) 172 44.2 0.0069 XP_016867977 (OMIM: 606833) PREDICTED: histone-lys (4922) 172 44.2 0.0069 XP_006716142 (OMIM: 606833) PREDICTED: histone-lys (4927) 172 44.2 0.0069 XP_005250088 (OMIM: 606833) PREDICTED: histone-lys (4928) 172 44.2 0.0069 XP_011514754 (OMIM: 606833) PREDICTED: histone-lys (4932) 172 44.2 0.0069 XP_016867976 (OMIM: 606833) PREDICTED: histone-lys (4934) 172 44.2 0.0069 XP_011514753 (OMIM: 606833) PREDICTED: histone-lys (4943) 172 44.2 0.0069 XP_016867975 (OMIM: 606833) PREDICTED: histone-lys (4954) 172 44.2 0.007 XP_006716141 (OMIM: 606833) PREDICTED: histone-lys (4959) 172 44.2 0.007 XP_011514758 (OMIM: 606833) PREDICTED: histone-lys (4963) 172 44.2 0.007 XP_016867974 (OMIM: 606833) PREDICTED: histone-lys (4966) 172 44.2 0.007 XP_011514752 (OMIM: 606833) PREDICTED: histone-lys (4967) 172 44.2 0.007 XP_016867973 (OMIM: 606833) PREDICTED: histone-lys (4972) 172 44.2 0.007 XP_016867972 (OMIM: 606833) PREDICTED: histone-lys (4978) 172 44.2 0.007 XP_016867971 (OMIM: 606833) PREDICTED: histone-lys (4978) 172 44.2 0.007 XP_005250085 (OMIM: 606833) PREDICTED: histone-lys (4979) 172 44.2 0.007 XP_006716140 (OMIM: 606833) PREDICTED: histone-lys (4982) 172 44.2 0.007 XP_016867970 (OMIM: 606833) PREDICTED: histone-lys (4982) 172 44.2 0.007 XP_005250084 (OMIM: 606833) PREDICTED: histone-lys (4982) 172 44.2 0.007 XP_005250083 (OMIM: 606833) PREDICTED: histone-lys (4982) 172 44.2 0.007 XP_005250082 (OMIM: 606833) PREDICTED: histone-lys (4983) 172 44.2 0.007 XP_016867969 (OMIM: 606833) PREDICTED: histone-lys (4983) 172 44.2 0.007 >>NP_001035533 (OMIM: 147050,600807,607796) PHD finger p (331 aa) initn: 2234 init1: 2234 opt: 2234 Z-score: 2390.0 bits: 450.6 E(85289): 2.2e-126 Smith-Waterman score: 2234; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331) 10 20 30 40 50 60 pF1KB0 MAQASPPRPERVLGASSPEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNVLYFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQASPPRPERVLGASSPEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNVLYFA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 QSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 GCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 KKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 VHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEI 250 260 270 280 290 300 310 320 330 pF1KB0 ELLQDLKQTLCSFQENRDLMSSSTSISSLSY ::::::::::::::::::::::::::::::: NP_001 ELLQDLKQTLCSFQENRDLMSSSTSISSLSY 310 320 330 >>NP_001035534 (OMIM: 147050,600807,607796) PHD finger p (292 aa) initn: 1981 init1: 1981 opt: 1981 Z-score: 2121.0 bits: 400.6 E(85289): 2.1e-111 Smith-Waterman score: 1981; 100.0% identity (100.0% similar) in 292 aa overlap (40-331:1-292) 10 20 30 40 50 60 pF1KB0 ERVLGASSPEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNVLYFAQSENIAAHE :::::::::::::::::::::::::::::: NP_001 MEKRTCALCPKDVEYNVLYFAQSENIAAHE 10 20 30 70 80 90 100 110 120 pF1KB0 NCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNK 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB0 NYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHV 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB0 QPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLM 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB0 DETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQT 220 230 240 250 260 270 310 320 330 pF1KB0 LCSFQENRDLMSSSTSISSLSY :::::::::::::::::::::: NP_001 LCSFQENRDLMSSSTSISSLSY 280 290 >>NP_115711 (OMIM: 300414,301900) PHD finger protein 6 i (312 aa) initn: 341 init1: 257 opt: 352 Z-score: 382.9 bits: 79.1 E(85289): 1.4e-14 Smith-Waterman score: 352; 37.5% identity (72.1% similar) in 136 aa overlap (29-161:1-133) 10 20 30 40 50 pF1KB0 MAQASPPRPERVLGASSPEARPAQEALLLPTGVFQVAEKMEKRTCALCP--KDVEYNVLY . ..: : ..: :..: .: : . : NP_115 MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLL 10 20 30 60 70 80 90 100 110 pF1KB0 FAQSENIAAHENCLLYSSGLVECE-DQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRG .......:::..:.:.::.:: . :.. :. .:..:.:.:::.:: :: :..:: : NP_115 ISENQKVAAHHKCMLFSSALVSSHSDNESLG---GFSIEDVQKEIKRGTKLMCSLCHCPG 40 50 60 70 80 120 130 140 150 160 170 pF1KB0 ATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRK ::.:::.:.:...::. :: .: : . .::: . :..: . NP_115 ATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEAADLEESFNE 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB0 RGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEI NP_115 HELEPSSPKSKKKSRKGRPRKTNFKGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDT 150 160 170 180 190 200 >>NP_001015877 (OMIM: 300414,301900) PHD finger protein (365 aa) initn: 376 init1: 258 opt: 311 Z-score: 338.1 bits: 71.0 E(85289): 4.3e-12 Smith-Waterman score: 352; 37.5% identity (72.1% similar) in 136 aa overlap (29-161:1-133) 10 20 30 40 50 pF1KB0 MAQASPPRPERVLGASSPEARPAQEALLLPTGVFQVAEKMEKRTCALCP--KDVEYNVLY . ..: : ..: :..: .: : . : NP_001 MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLL 10 20 30 60 70 80 90 100 110 pF1KB0 FAQSENIAAHENCLLYSSGLVECE-DQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRG .......:::..:.:.::.:: . :.. :. .:..:.:.:::.:: :: :..:: : NP_001 ISENQKVAAHHKCMLFSSALVSSHSDNESLG---GFSIEDVQKEIKRGTKLMCSLCHCPG 40 50 60 70 80 120 130 140 150 160 170 pF1KB0 ATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRK ::.:::.:.:...::. :: .: : . .::: . :..: . NP_001 ATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEESFNEH 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB0 RGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEI NP_001 ELEPSSPKSKKKSRKGRPRKTNFKGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDTR 150 160 170 180 190 200 >-- initn: 401 init1: 258 opt: 311 Z-score: 338.1 bits: 71.0 E(85289): 4.3e-12 Smith-Waterman score: 311; 37.5% identity (67.5% similar) in 120 aa overlap (45-160:212-330) 20 30 40 50 60 70 pF1KB0 ASSPEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNV----LYFAQSENIAAHEN :..: : : :.. .... ::: . NP_001 TSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHYK 190 200 210 220 230 240 80 90 100 110 120 130 pF1KB0 CLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKN :.:.::: :. . . .::...: .::.::...:: .: . :::.::..: : :. NP_001 CMLFSSGTVQLTTTSRAEFG-DFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKT 250 260 270 280 290 300 140 150 160 170 180 190 pF1KB0 YHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQ ::. :. .: : . :::::: :..:. NP_001 YHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQQQLTQQ 310 320 330 340 350 360 >>NP_115834 (OMIM: 300414,301900) PHD finger protein 6 i (365 aa) initn: 376 init1: 258 opt: 311 Z-score: 338.1 bits: 71.0 E(85289): 4.3e-12 Smith-Waterman score: 352; 37.5% identity (72.1% similar) in 136 aa overlap (29-161:1-133) 10 20 30 40 50 pF1KB0 MAQASPPRPERVLGASSPEARPAQEALLLPTGVFQVAEKMEKRTCALCP--KDVEYNVLY . ..: : ..: :..: .: : . : NP_115 MSSSVEQKKGPTRQRKCGFCKSNRDKECGQLL 10 20 30 60 70 80 90 100 110 pF1KB0 FAQSENIAAHENCLLYSSGLVECE-DQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRG .......:::..:.:.::.:: . :.. :. .:..:.:.:::.:: :: :..:: : NP_115 ISENQKVAAHHKCMLFSSALVSSHSDNESLG---GFSIEDVQKEIKRGTKLMCSLCHCPG 40 50 60 70 80 120 130 140 150 160 170 pF1KB0 ATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRK ::.:::.:.:...::. :: .: : . .::: . :..: . NP_115 ATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEESFNEH 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB0 RGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEI NP_115 ELEPSSPKSKKKSRKGRPRKTNFKGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDTR 150 160 170 180 190 200 >-- initn: 401 init1: 258 opt: 311 Z-score: 338.1 bits: 71.0 E(85289): 4.3e-12 Smith-Waterman score: 311; 37.5% identity (67.5% similar) in 120 aa overlap (45-160:212-330) 20 30 40 50 60 70 pF1KB0 ASSPEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNV----LYFAQSENIAAHEN :..: : : :.. .... ::: . NP_115 TSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFNAKKAAAHYK 190 200 210 220 230 240 80 90 100 110 120 130 pF1KB0 CLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKN :.:.::: :. . . .::...: .::.::...:: .: . :::.::..: : :. NP_115 CMLFSSGTVQLTTTSRAEFG-DFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKT 250 260 270 280 290 300 140 150 160 170 180 190 pF1KB0 YHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQ ::. :. .: : . :::::: :..:. NP_115 YHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGKVEIDQQQLTQQ 310 320 330 340 350 360 >>NP_060239 (OMIM: 611299) G2/M phase-specific E3 ubiqui (706 aa) initn: 214 init1: 159 opt: 235 Z-score: 252.7 bits: 56.2 E(85289): 2.4e-07 Smith-Waterman score: 235; 24.7% identity (52.9% similar) in 223 aa overlap (48-268:23-233) 20 30 40 50 60 70 pF1KB0 PEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSG ::. .:. .. :...: :::.::: NP_060 MNESKPGDSQNLACVFCRKHDDCPN--KYGEKKTKEKWNLTVHYYCLLMSSG 10 20 30 40 50 80 90 100 110 120 130 pF1KB0 LVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAK . . .. . .: .:...::..:. :::: :.: ::..:: :...::: :. NP_060 IWQRGKEE--EGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGL 60 70 80 90 100 140 150 160 170 180 190 pF1KB0 KDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRK--KPLSGNHVQPPETM . . . : : . .: .: ::... .. . .:. . .. NP_060 QRECIFQ---FTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCC 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB0 KCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSE : : :. . .. .: : :. .: . . . .:.: :::: . : NP_060 KNAWFHRDCLQVQA--INAGV---FFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEE 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB0 SDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQE . :.:. . : NP_060 NAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNW 230 240 250 260 270 280 >>XP_011535227 (OMIM: 611299) PREDICTED: G2/M phase-spec (706 aa) initn: 214 init1: 159 opt: 235 Z-score: 252.7 bits: 56.2 E(85289): 2.4e-07 Smith-Waterman score: 235; 24.7% identity (52.9% similar) in 223 aa overlap (48-268:23-233) 20 30 40 50 60 70 pF1KB0 PEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSG ::. .:. .. :...: :::.::: XP_011 MNESKPGDSQNLACVFCRKHDDCPN--KYGEKKTKEKWNLTVHYYCLLMSSG 10 20 30 40 50 80 90 100 110 120 130 pF1KB0 LVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAK . . .. . .: .:...::..:. :::: :.: ::..:: :...::: :. XP_011 IWQRGKEE--EGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGL 60 70 80 90 100 140 150 160 170 180 190 pF1KB0 KDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRK--KPLSGNHVQPPETM . . . : : . .: .: ::... .. . .:. . .. XP_011 QRECIFQ---FTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCC 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB0 KCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSE : : :. . .. .: : :. .: . . . .:.: :::: . : XP_011 KNAWFHRDCLQVQA--INAGV---FFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEE 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB0 SDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQE . :.:. . : XP_011 NAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNW 230 240 250 260 270 280 >>XP_011535228 (OMIM: 611299) PREDICTED: G2/M phase-spec (667 aa) initn: 214 init1: 159 opt: 230 Z-score: 247.8 bits: 55.2 E(85289): 4.6e-07 Smith-Waterman score: 230; 30.6% identity (62.0% similar) in 121 aa overlap (48-168:23-136) 20 30 40 50 60 70 pF1KB0 PEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSG ::. .:. .. :...: :::.::: XP_011 MNESKPGDSQNLACVFCRKHDDCPN--KYGEKKTKEKWNLTVHYYCLLMSSG 10 20 30 40 50 80 90 100 110 120 130 pF1KB0 LVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAK . . .. . .: .:...::..:. :::: :.: ::..:: :...::: :. XP_011 IWQRGKEE--EGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGL 60 70 80 90 100 140 150 160 170 180 190 pF1KB0 KDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKC . . . : : . .: .: ::... XP_011 QRECIFQ---FTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCC 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB0 NTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESD XP_011 KNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGIHIPENKWEIKRCQCCGSS 170 180 190 200 210 220 >>XP_006718902 (OMIM: 159555,605130) PREDICTED: histone- (3133 aa) initn: 218 init1: 179 opt: 209 Z-score: 215.2 bits: 51.4 E(85289): 3e-05 Smith-Waterman score: 259; 34.4% identity (58.1% similar) in 160 aa overlap (6-159:1007-1141) 10 20 30 pF1KB0 MAQASPPRPERVLGASSPEARPAQEALLLPTGVFQ :: : .: :. ..: . : : :. XP_006 HTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPP-IL--STDRSREDSPELNPPPGI-- 980 990 1000 1010 1020 1030 40 50 60 70 80 pF1KB0 VAEKMEKRTCALCPK--DVEYN----VLYFAQSENIAAHENCLLYSSGLVECEDQDPLNP ..: :::: : : .::..:.: .: :: :.:. . : :.: XP_006 ----EDNRQCALCLTYGDDSANDAGRLLYIGQNE--WTHVNCALWSAEVFE--DDDG--- 1040 1050 1060 1070 1080 90 100 110 120 130 140 pF1KB0 DRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVR ....:. . ::..:.:.::.: :::::: : .:..::::.:.. . : .: XP_006 ----SLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDK-- 1090 1100 1110 1120 1130 150 160 170 180 190 200 pF1KB0 GIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEEHG :. ::.: XP_006 ---KVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMT 1140 1150 1160 1170 1180 1190 >>XP_011541135 (OMIM: 159555,605130) PREDICTED: histone- (3166 aa) initn: 218 init1: 179 opt: 209 Z-score: 215.2 bits: 51.4 E(85289): 3e-05 Smith-Waterman score: 259; 34.4% identity (58.1% similar) in 160 aa overlap (6-159:1040-1174) 10 20 30 pF1KB0 MAQASPPRPERVLGASSPEARPAQEALLLPTGVFQ :: : .: :. ..: . : : :. XP_011 HTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPP-IL--STDRSREDSPELNPPPGI-- 1010 1020 1030 1040 1050 1060 40 50 60 70 80 pF1KB0 VAEKMEKRTCALCPK--DVEYN----VLYFAQSENIAAHENCLLYSSGLVECEDQDPLNP ..: :::: : : .::..:.: .: :: :.:. . : :.: XP_011 ----EDNRQCALCLTYGDDSANDAGRLLYIGQNE--WTHVNCALWSAEVFE--DDDG--- 1070 1080 1090 1100 1110 90 100 110 120 130 140 pF1KB0 DRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVR ....:. . ::..:.:.::.: :::::: : .:..::::.:.. . : .: XP_011 ----SLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDK-- 1120 1130 1140 1150 1160 150 160 170 180 190 200 pF1KB0 GIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEEHG :. ::.: XP_011 ---KVYCQRHRDLIKGEVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMT 1170 1180 1190 1200 1210 1220 331 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:14:25 2016 done: Sat Nov 5 17:14:27 2016 Total Scan time: 7.630 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]