FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0928, 364 aa 1>>>pF1KB0928 364 - 364 aa - 364 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6837+/-0.000512; mu= 18.1625+/- 0.033 mean_var=227.7636+/-57.872, 0's: 0 Z-trim(114.2): 104 B-trim: 2678 in 2/50 Lambda= 0.084983 statistics sampled from 23765 (23905) to 23765 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.28), width: 16 Scan time: 7.820 The best scores are: opt bits E(85289) NP_002887 (OMIM: 602571) RNA-binding protein 4 iso ( 364) 2388 306.1 7.9e-83 NP_001185773 (OMIM: 602571) RNA-binding protein 4 ( 173) 911 124.5 1.8e-28 NP_001185772 (OMIM: 602571) RNA-binding protein 4 ( 143) 905 123.6 2.7e-28 NP_006319 (OMIM: 612409) RNA-binding protein 14 is ( 669) 471 71.5 6e-12 NP_001185765 (OMIM: 612409) RNA-binding protein 14 ( 156) 433 65.8 7.5e-11 NP_001185766 (OMIM: 612409) RNA-binding protein 14 ( 119) 301 49.4 4.9e-06 >>NP_002887 (OMIM: 602571) RNA-binding protein 4 isoform (364 aa) initn: 2388 init1: 2388 opt: 2388 Z-score: 1608.0 bits: 306.1 E(85289): 7.9e-83 Smith-Waterman score: 2388; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364) 10 20 30 40 50 60 pF1KB0 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPIDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPIDRS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 GRVADLTEQYNEQYGAVRTPYTMSYGDSLYYNNAYGALDAYYKRCRAARSYEAVAAAAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GRVADLTEQYNEQYGAVRTPYTMSYGDSLYYNNAYGALDAYYKRCRAARSYEAVAAAAAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 VYNYAEQTLSQLPQVQNTAMASHLTSTSLDPYDRHLLPTSGAAATAAAAAAAAAAVTAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VYNYAEQTLSQLPQVQNTAMASHLTSTSLDPYDRHLLPTSGAAATAAAAAAAAAAVTAAS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 TSYYGRDRSPLRRATAPVPTVGEGYGYGHESELSQASAAARNSLYDMARYEREQYADRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TSYYGRDRSPLRRATAPVPTVGEGYGYGHESELSQASAAARNSLYDMARYEREQYADRAR 310 320 330 340 350 360 pF1KB0 YSAF :::: NP_002 YSAF >>NP_001185773 (OMIM: 602571) RNA-binding protein 4 isof (173 aa) initn: 911 init1: 911 opt: 911 Z-score: 632.1 bits: 124.5 E(85289): 1.8e-28 Smith-Waterman score: 911; 100.0% identity (100.0% similar) in 139 aa overlap (1-139:1-139) 10 20 30 40 50 60 pF1KB0 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPIDRS ::::::::::::::::::: NP_001 AEDAVEAIRGLDNTEFQGKITPVTEGYCCCNKGHTYIFKNCNLILESRKSRRC 130 140 150 160 170 >>NP_001185772 (OMIM: 602571) RNA-binding protein 4 isof (143 aa) initn: 905 init1: 905 opt: 905 Z-score: 628.9 bits: 123.6 E(85289): 2.7e-28 Smith-Waterman score: 905; 100.0% identity (100.0% similar) in 138 aa overlap (1-138:1-138) 10 20 30 40 50 60 pF1KB0 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPIDRS :::::::::::::::::: NP_001 AEDAVEAIRGLDNTEFQGGMCVG 130 140 >>NP_006319 (OMIM: 612409) RNA-binding protein 14 isofor (669 aa) initn: 505 init1: 322 opt: 471 Z-score: 335.5 bits: 71.5 E(85289): 6e-12 Smith-Waterman score: 487; 34.3% identity (59.8% similar) in 321 aa overlap (2-305:1-319) 10 20 30 40 50 pF1KB0 MVKLFIGNLP-REATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYK .:.:.::. ..: .:. .:: :: :. : ..:...:::......: ::. :: .. NP_006 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHE 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 LH-GVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHM :. : . :: :. . .. :. :::.: .::..:::. ::. : :::::.::::::::: NP_006 LRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 ERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPID :. :: :: :.. : .:::..:.:::. . .::.. ::: . : : . : NP_006 EKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSG-DKTKKPGAGDTAFP-G 120 130 140 150 160 170 180 190 200 210 220 pF1KB0 RSGRVA--DLTEQYNEQYGA----VRTPYTMSYG---DSLYYN---NAYGA-LDAYYKRC .: : : . .... :. .: : .: . : . .: : : : NP_006 TGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATY 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB0 RAARSYEAVAAAAASVYNYAEQTLSQLPQVQNTAMASHLTSTSLD-PYDRHLL-PTSGAA :: : :: :. :.. ..: :.:: :: .: :.: .: NP_006 RAQPSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSA 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB0 ATAAAAAAAAAAVTAASTSYYGRDRSPLRRATAPVPTVGEGYGYGHESELSQASAAARNS :... . ..: .:.. : :: NP_006 AASSLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYG 300 310 320 330 340 350 >>NP_001185765 (OMIM: 612409) RNA-binding protein 14 iso (156 aa) initn: 391 init1: 288 opt: 433 Z-score: 315.8 bits: 65.8 E(85289): 7.5e-11 Smith-Waterman score: 433; 45.3% identity (75.7% similar) in 148 aa overlap (2-147:1-148) 10 20 30 40 50 pF1KB0 MVKLFIGNLP-REATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYK .:.:.::. ..: .:. .:: :: :. : ..:...:::......: ::. :: .. NP_001 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHE 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 LH-GVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHM :. : . :: :. . .. :. :::.: .::..:::. ::. : :::::.::::::::: NP_001 LRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 ERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPID :. :: :: :.. : .:::..:.::: NP_001 EKEADAKAAIAQLNGKEVKGKRINVELSTKGMVPTGV 120 130 140 150 >>NP_001185766 (OMIM: 612409) RNA-binding protein 14 iso (119 aa) initn: 259 init1: 156 opt: 301 Z-score: 229.3 bits: 49.4 E(85289): 4.9e-06 Smith-Waterman score: 301; 41.1% identity (75.0% similar) in 112 aa overlap (2-111:1-112) 10 20 30 40 50 pF1KB0 MVKLFIGNLP-REATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYK .:.:.::. ..: .:. .:: :: :. : ..:...:::......: ::. :: .. NP_001 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHE 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 LH-GVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHM :. : . :: :. . .. :. :::.: .::..:::. ::. : :::::.:: NP_001 LRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKGMVPTGV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 ERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPID 364 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:57:36 2016 done: Sat Nov 5 17:57:37 2016 Total Scan time: 7.820 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]