FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0931, 145 aa 1>>>pF1KB0931 145 - 145 aa - 145 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0150+/-0.000424; mu= 7.8422+/- 0.026 mean_var=146.1914+/-32.226, 0's: 0 Z-trim(115.3): 406 B-trim: 752 in 2/51 Lambda= 0.106075 statistics sampled from 25061 (25671) to 25061 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.301), width: 16 Scan time: 4.570 The best scores are: opt bits E(85289) NP_060843 (OMIM: 609411) synaptojanin-2-binding pr ( 145) 958 157.8 5.8e-39 XP_011510811 (OMIM: 601014) PREDICTED: disks large ( 554) 283 55.2 1.7e-07 NP_001308005 (OMIM: 602887) disks large homolog 4 ( 664) 282 55.1 2.1e-07 NP_001308006 (OMIM: 602887) disks large homolog 4 ( 664) 282 55.1 2.1e-07 XP_011522004 (OMIM: 602887) PREDICTED: disks large ( 664) 282 55.1 2.1e-07 NP_001191317 (OMIM: 601014) disks large homolog 1 ( 788) 283 55.3 2.1e-07 NP_001191316 (OMIM: 601014) disks large homolog 1 ( 800) 283 55.3 2.2e-07 XP_016861312 (OMIM: 601014) PREDICTED: disks large ( 810) 283 55.4 2.2e-07 XP_016861311 (OMIM: 601014) PREDICTED: disks large ( 821) 283 55.4 2.2e-07 XP_016879779 (OMIM: 602887) PREDICTED: disks large ( 697) 282 55.1 2.2e-07 XP_016879778 (OMIM: 602887) PREDICTED: disks large ( 699) 282 55.1 2.2e-07 XP_016879777 (OMIM: 602887) PREDICTED: disks large ( 702) 282 55.1 2.2e-07 XP_016861310 (OMIM: 601014) PREDICTED: disks large ( 843) 283 55.4 2.2e-07 NP_001122299 (OMIM: 602887) disks large homolog 4 ( 721) 282 55.1 2.3e-07 XP_011510808 (OMIM: 601014) PREDICTED: disks large ( 853) 283 55.4 2.3e-07 XP_016861309 (OMIM: 601014) PREDICTED: disks large ( 853) 283 55.4 2.3e-07 NP_001308004 (OMIM: 602887) disks large homolog 4 ( 724) 282 55.1 2.3e-07 XP_016861306 (OMIM: 601014) PREDICTED: disks large ( 871) 283 55.4 2.3e-07 XP_016861307 (OMIM: 601014) PREDICTED: disks large ( 871) 283 55.4 2.3e-07 XP_016861305 (OMIM: 601014) PREDICTED: disks large ( 871) 283 55.4 2.3e-07 XP_011510807 (OMIM: 601014) PREDICTED: disks large ( 871) 283 55.4 2.3e-07 XP_016861308 (OMIM: 601014) PREDICTED: disks large ( 871) 283 55.4 2.3e-07 XP_016861304 (OMIM: 601014) PREDICTED: disks large ( 874) 283 55.4 2.3e-07 XP_016861300 (OMIM: 601014) PREDICTED: disks large ( 875) 283 55.4 2.3e-07 XP_016861303 (OMIM: 601014) PREDICTED: disks large ( 875) 283 55.4 2.3e-07 XP_016861301 (OMIM: 601014) PREDICTED: disks large ( 875) 283 55.4 2.3e-07 XP_016861302 (OMIM: 601014) PREDICTED: disks large ( 875) 283 55.4 2.3e-07 XP_005256548 (OMIM: 602887) PREDICTED: disks large ( 754) 282 55.2 2.3e-07 XP_011510805 (OMIM: 601014) PREDICTED: disks large ( 892) 283 55.4 2.3e-07 XP_016861299 (OMIM: 601014) PREDICTED: disks large ( 892) 283 55.4 2.3e-07 NP_001191315 (OMIM: 601014) disks large homolog 1 ( 892) 283 55.4 2.3e-07 XP_016861296 (OMIM: 601014) PREDICTED: disks large ( 893) 283 55.4 2.3e-07 XP_016861297 (OMIM: 601014) PREDICTED: disks large ( 893) 283 55.4 2.3e-07 XP_016861295 (OMIM: 601014) PREDICTED: disks large ( 893) 283 55.4 2.3e-07 XP_016861298 (OMIM: 601014) PREDICTED: disks large ( 893) 283 55.4 2.3e-07 NP_001308003 (OMIM: 602887) disks large homolog 4 ( 764) 282 55.2 2.3e-07 XP_011510804 (OMIM: 601014) PREDICTED: disks large ( 904) 283 55.4 2.3e-07 NP_001091894 (OMIM: 601014) disks large homolog 1 ( 904) 283 55.4 2.3e-07 XP_016861294 (OMIM: 601014) PREDICTED: disks large ( 904) 283 55.4 2.3e-07 NP_001277912 (OMIM: 601014) disks large homolog 1 ( 904) 283 55.4 2.3e-07 NP_001356 (OMIM: 602887) disks large homolog 4 iso ( 767) 282 55.2 2.3e-07 XP_016861293 (OMIM: 601014) PREDICTED: disks large ( 925) 283 55.4 2.4e-07 XP_016861290 (OMIM: 601014) PREDICTED: disks large ( 926) 283 55.4 2.4e-07 XP_005269346 (OMIM: 601014) PREDICTED: disks large ( 926) 283 55.4 2.4e-07 XP_016861292 (OMIM: 601014) PREDICTED: disks large ( 926) 283 55.4 2.4e-07 XP_016861289 (OMIM: 601014) PREDICTED: disks large ( 926) 283 55.4 2.4e-07 XP_016861291 (OMIM: 601014) PREDICTED: disks large ( 926) 283 55.4 2.4e-07 NP_004078 (OMIM: 601014) disks large homolog 1 iso ( 926) 283 55.4 2.4e-07 XP_011522001 (OMIM: 602887) PREDICTED: disks large ( 797) 282 55.2 2.4e-07 XP_011522000 (OMIM: 602887) PREDICTED: disks large ( 797) 282 55.2 2.4e-07 >>NP_060843 (OMIM: 609411) synaptojanin-2-binding protei (145 aa) initn: 958 init1: 958 opt: 958 Z-score: 820.4 bits: 157.8 E(85289): 5.8e-39 Smith-Waterman score: 958; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145) 10 20 30 40 50 60 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 EGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGHRGEGDPSGIPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGHRGEGDPSGIPI 70 80 90 100 110 120 130 140 pF1KB0 FMVLVPVFALTMVAAWAFMRYRQQL ::::::::::::::::::::::::: NP_060 FMVLVPVFALTMVAAWAFMRYRQQL 130 140 >>XP_011510811 (OMIM: 601014) PREDICTED: disks large hom (554 aa) initn: 450 init1: 279 opt: 283 Z-score: 255.5 bits: 55.2 E(85289): 1.7e-07 Smith-Waterman score: 283; 42.0% identity (71.4% similar) in 119 aa overlap (1-118:180-296) 10 20 pF1KB0 MNGR-VDYLVTEEEINLTRGPSGLGFNIVG .:: .:: :::.: :: :::::.:.: XP_011 GFVSHSHISPIKANPPPVLVNTDSLETPTYVNGTDADY--EYEEITLERGNSGLGFSIAG 150 160 170 180 190 200 30 40 50 60 70 80 pF1KB0 GTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAG :::. ....::.:....: .:::: ::::. .: :: :: :.... :. ::. ...:: XP_011 GTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAG 210 220 230 240 250 260 90 100 110 120 130 140 pF1KB0 YAVSLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL : : :..: :.. . . :.:. XP_011 SIVRLYVKRRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAH 270 280 290 300 310 320 >-- initn: 253 init1: 167 opt: 238 Z-score: 218.3 bits: 48.3 E(85289): 2e-05 Smith-Waterman score: 238; 43.8% identity (70.8% similar) in 96 aa overlap (6-99:424-513) 10 20 30 pF1KB0 MNGRVDYLVTEE--EINLTRGPSGLGFNIVGGTDQ : .:.: .. : :: .::::::::: : XP_011 VDNHVSPSSFLGQTPASPARYSPVSKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDG 400 410 420 430 440 450 40 50 60 70 80 90 pF1KB0 QYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVS . ::..: : .: : :.:.:..::.:.:::. ::. :..:. ..::: ::. XP_011 E------GIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVT 460 470 480 490 500 100 110 120 130 140 pF1KB0 LRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL . .:.: XP_011 IVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVR 510 520 530 540 550 >-- initn: 365 init1: 212 opt: 212 Z-score: 196.8 bits: 44.3 E(85289): 0.00032 Smith-Waterman score: 212; 45.2% identity (80.8% similar) in 73 aa overlap (24-96:297-369) 10 20 30 40 50 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAA ::.:.::. .:.. .:..:::..: :.::: XP_011 GSIVRLYVKRRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAA 270 280 290 300 310 320 60 70 80 90 100 110 pF1KB0 ALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGHRGEG ::.:: :::.:.::. :... :..:: ..:.. : :.: XP_011 HKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGYAPPDI 330 340 350 360 370 380 120 130 140 pF1KB0 DPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL XP_011 TNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVLGDDEITREPRKVVLHRGSTGLGFN 390 400 410 420 430 440 >>NP_001308005 (OMIM: 602887) disks large homolog 4 isof (664 aa) initn: 431 init1: 272 opt: 282 Z-score: 253.8 bits: 55.1 E(85289): 2.1e-07 Smith-Waterman score: 282; 51.2% identity (83.3% similar) in 84 aa overlap (13-96:100-183) 10 20 30 40 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGI ::.: .::.::::.:.::. .:.. .:..: NP_001 HSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSI 70 80 90 100 110 120 50 60 70 80 90 100 pF1KB0 YVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQV ::..: :.::: ::::: :::::.::. :....:.::: ..:. .: :.: NP_001 YVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNA 130 140 150 160 170 180 110 120 130 140 pF1KB0 QNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL NP_001 YLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPR 190 200 210 220 230 240 >-- initn: 292 init1: 268 opt: 268 Z-score: 242.2 bits: 53.0 E(85289): 9.4e-07 Smith-Waterman score: 268; 47.7% identity (79.5% similar) in 88 aa overlap (12-99:4-91) 10 20 30 40 50 60 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQ :::.: :: :::::.:.::::. ....: .:....: .:::: ::::. NP_001 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLR 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 EGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGHRGEGDPSGIPI .:.:: :: :.... :. ::. ...:: : : :..: NP_001 VNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGF 60 70 80 90 100 110 130 140 pF1KB0 FMVLVPVFALTMVAAWAFMRYRQQL NP_001 SIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAAL 120 130 140 150 160 170 >-- initn: 261 init1: 173 opt: 241 Z-score: 219.9 bits: 48.8 E(85289): 1.7e-05 Smith-Waterman score: 241; 43.3% identity (70.1% similar) in 97 aa overlap (3-99:243-333) 10 20 30 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTD :. : ..: . :: .::::::::: : NP_001 SHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGED 220 230 240 250 260 270 40 50 60 70 80 90 pF1KB0 QQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAV . ::..: : .: : :.:.:..::.:::::: ::.: :..:. ..::: .: NP_001 GE------GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTV 280 290 300 310 320 100 110 120 130 140 pF1KB0 SLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL .. .:.. NP_001 TIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCG 330 340 350 360 370 380 >>NP_001308006 (OMIM: 602887) disks large homolog 4 isof (664 aa) initn: 431 init1: 272 opt: 282 Z-score: 253.8 bits: 55.1 E(85289): 2.1e-07 Smith-Waterman score: 282; 51.2% identity (83.3% similar) in 84 aa overlap (13-96:100-183) 10 20 30 40 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGI ::.: .::.::::.:.::. .:.. .:..: NP_001 HSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSI 70 80 90 100 110 120 50 60 70 80 90 100 pF1KB0 YVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQV ::..: :.::: ::::: :::::.::. :....:.::: ..:. .: :.: NP_001 YVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNA 130 140 150 160 170 180 110 120 130 140 pF1KB0 QNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL NP_001 YLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPR 190 200 210 220 230 240 >-- initn: 292 init1: 268 opt: 268 Z-score: 242.2 bits: 53.0 E(85289): 9.4e-07 Smith-Waterman score: 268; 47.7% identity (79.5% similar) in 88 aa overlap (12-99:4-91) 10 20 30 40 50 60 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQ :::.: :: :::::.:.::::. ....: .:....: .:::: ::::. NP_001 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLR 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 EGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGHRGEGDPSGIPI .:.:: :: :.... :. ::. ...:: : : :..: NP_001 VNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGF 60 70 80 90 100 110 130 140 pF1KB0 FMVLVPVFALTMVAAWAFMRYRQQL NP_001 SIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAAL 120 130 140 150 160 170 >-- initn: 261 init1: 173 opt: 241 Z-score: 219.9 bits: 48.8 E(85289): 1.7e-05 Smith-Waterman score: 241; 43.3% identity (70.1% similar) in 97 aa overlap (3-99:243-333) 10 20 30 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTD :. : ..: . :: .::::::::: : NP_001 SHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGED 220 230 240 250 260 270 40 50 60 70 80 90 pF1KB0 QQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAV . ::..: : .: : :.:.:..::.:::::: ::.: :..:. ..::: .: NP_001 GE------GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTV 280 290 300 310 320 100 110 120 130 140 pF1KB0 SLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL .. .:.. NP_001 TIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCG 330 340 350 360 370 380 >>XP_011522004 (OMIM: 602887) PREDICTED: disks large hom (664 aa) initn: 431 init1: 272 opt: 282 Z-score: 253.8 bits: 55.1 E(85289): 2.1e-07 Smith-Waterman score: 282; 51.2% identity (83.3% similar) in 84 aa overlap (13-96:100-183) 10 20 30 40 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGI ::.: .::.::::.:.::. .:.. .:..: XP_011 HSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSI 70 80 90 100 110 120 50 60 70 80 90 100 pF1KB0 YVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQV ::..: :.::: ::::: :::::.::. :....:.::: ..:. .: :.: XP_011 YVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNA 130 140 150 160 170 180 110 120 130 140 pF1KB0 QNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL XP_011 YLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPR 190 200 210 220 230 240 >-- initn: 292 init1: 268 opt: 268 Z-score: 242.2 bits: 53.0 E(85289): 9.4e-07 Smith-Waterman score: 268; 47.7% identity (79.5% similar) in 88 aa overlap (12-99:4-91) 10 20 30 40 50 60 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQ :::.: :: :::::.:.::::. ....: .:....: .:::: ::::. XP_011 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLR 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 EGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGHRGEGDPSGIPI .:.:: :: :.... :. ::. ...:: : : :..: XP_011 VNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGF 60 70 80 90 100 110 130 140 pF1KB0 FMVLVPVFALTMVAAWAFMRYRQQL XP_011 SIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAAL 120 130 140 150 160 170 >-- initn: 261 init1: 173 opt: 241 Z-score: 219.9 bits: 48.8 E(85289): 1.7e-05 Smith-Waterman score: 241; 43.3% identity (70.1% similar) in 97 aa overlap (3-99:243-333) 10 20 30 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTD :. : ..: . :: .::::::::: : XP_011 SHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGED 220 230 240 250 260 270 40 50 60 70 80 90 pF1KB0 QQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAV . ::..: : .: : :.:.:..::.:::::: ::.: :..:. ..::: .: XP_011 GE------GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTV 280 290 300 310 320 100 110 120 130 140 pF1KB0 SLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL .. .:.. XP_011 TIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCG 330 340 350 360 370 380 >>NP_001191317 (OMIM: 601014) disks large homolog 1 isof (788 aa) initn: 432 init1: 279 opt: 283 Z-score: 253.8 bits: 55.3 E(85289): 2.1e-07 Smith-Waterman score: 283; 42.0% identity (71.4% similar) in 119 aa overlap (1-118:97-213) 10 20 pF1KB0 MNGR-VDYLVTEEEINLTRGPSGLGFNIVG .:: .:: :::.: :: :::::.:.: NP_001 IDCISVATSSTQANPPPVLVNTDSLETPTYVNGTDADY--EYEEITLERGNSGLGFSIAG 70 80 90 100 110 120 30 40 50 60 70 80 pF1KB0 GTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAG :::. ....::.:....: .:::: ::::. .: :: :: :.... :. ::. ...:: NP_001 GTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAG 130 140 150 160 170 180 90 100 110 120 130 140 pF1KB0 YAVSLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL : : :..: :.. . . :.:. NP_001 SIVRLYVKRRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAH 190 200 210 220 230 240 >>NP_001191316 (OMIM: 601014) disks large homolog 1 isof (800 aa) initn: 432 init1: 279 opt: 283 Z-score: 253.7 bits: 55.3 E(85289): 2.2e-07 Smith-Waterman score: 283; 42.0% identity (71.4% similar) in 119 aa overlap (1-118:97-213) 10 20 pF1KB0 MNGR-VDYLVTEEEINLTRGPSGLGFNIVG .:: .:: :::.: :: :::::.:.: NP_001 IDCISVATSSTQANPPPVLVNTDSLETPTYVNGTDADY--EYEEITLERGNSGLGFSIAG 70 80 90 100 110 120 30 40 50 60 70 80 pF1KB0 GTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAG :::. ....::.:....: .:::: ::::. .: :: :: :.... :. ::. ...:: NP_001 GTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAG 130 140 150 160 170 180 90 100 110 120 130 140 pF1KB0 YAVSLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL : : :..: :.. . . :.:. NP_001 SIVRLYVKRRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAH 190 200 210 220 230 240 >>XP_016861312 (OMIM: 601014) PREDICTED: disks large hom (810 aa) initn: 432 init1: 279 opt: 283 Z-score: 253.6 bits: 55.4 E(85289): 2.2e-07 Smith-Waterman score: 283; 42.0% identity (71.4% similar) in 119 aa overlap (1-118:97-213) 10 20 pF1KB0 MNGR-VDYLVTEEEINLTRGPSGLGFNIVG .:: .:: :::.: :: :::::.:.: XP_016 IDCISVATSSTQANPPPVLVNTDSLETPTYVNGTDADY--EYEEITLERGNSGLGFSIAG 70 80 90 100 110 120 30 40 50 60 70 80 pF1KB0 GTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAG :::. ....::.:....: .:::: ::::. .: :: :: :.... :. ::. ...:: XP_016 GTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAG 130 140 150 160 170 180 90 100 110 120 130 140 pF1KB0 YAVSLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL : : :..: :.. . . :.:. XP_016 SIVRLYVKRRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAH 190 200 210 220 230 240 >>XP_016861311 (OMIM: 601014) PREDICTED: disks large hom (821 aa) initn: 432 init1: 279 opt: 283 Z-score: 253.6 bits: 55.4 E(85289): 2.2e-07 Smith-Waterman score: 283; 42.0% identity (71.4% similar) in 119 aa overlap (1-118:130-246) 10 20 pF1KB0 MNGR-VDYLVTEEEINLTRGPSGLGFNIVG .:: .:: :::.: :: :::::.:.: XP_016 AENTVILPTIPQANPPPVLVNTDSLETPTYVNGTDADY--EYEEITLERGNSGLGFSIAG 100 110 120 130 140 150 30 40 50 60 70 80 pF1KB0 GTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAG :::. ....::.:....: .:::: ::::. .: :: :: :.... :. ::. ...:: XP_016 GTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAG 160 170 180 190 200 210 90 100 110 120 130 140 pF1KB0 YAVSLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL : : :..: :.. . . :.:. XP_016 SIVRLYVKRRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAH 220 230 240 250 260 270 >>XP_016879779 (OMIM: 602887) PREDICTED: disks large hom (697 aa) initn: 431 init1: 272 opt: 282 Z-score: 253.5 bits: 55.1 E(85289): 2.2e-07 Smith-Waterman score: 282; 51.2% identity (83.3% similar) in 84 aa overlap (13-96:133-216) 10 20 30 40 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGI ::.: .::.::::.:.::. .:.. .:..: XP_016 HSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSI 110 120 130 140 150 160 50 60 70 80 90 100 pF1KB0 YVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQV ::..: :.::: ::::: :::::.::. :....:.::: ..:. .: :.: XP_016 YVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNA 170 180 190 200 210 220 110 120 130 140 pF1KB0 QNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL XP_016 YLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPR 230 240 250 260 270 280 >-- initn: 291 init1: 268 opt: 269 Z-score: 242.8 bits: 53.1 E(85289): 8.7e-07 Smith-Waterman score: 269; 45.4% identity (77.3% similar) in 97 aa overlap (3-99:32-124) 10 20 30 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTD :...: :::.: :: :::::.:.:::: XP_016 GRTGEHQANSPPVIVNTDTLEAPGYVNGTEGEMEY----EEITLERGNSGLGFSIAGGTD 10 20 30 40 50 40 50 60 70 80 90 pF1KB0 QQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAV . ....: .:....: .:::: ::::. .:.:: :: :.... :. ::. ...:: : XP_016 NPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIV 60 70 80 90 100 110 100 110 120 130 140 pF1KB0 SLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL : :..: XP_016 RLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDG 120 130 140 150 160 170 >-- initn: 261 init1: 173 opt: 241 Z-score: 219.6 bits: 48.8 E(85289): 1.7e-05 Smith-Waterman score: 241; 43.3% identity (70.1% similar) in 97 aa overlap (3-99:276-366) 10 20 30 pF1KB0 MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTD :. : ..: . :: .::::::::: : XP_016 SHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGED 250 260 270 280 290 300 40 50 60 70 80 90 pF1KB0 QQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAV . ::..: : .: : :.:.:..::.:::::: ::.: :..:. ..::: .: XP_016 GE------GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTV 310 320 330 340 350 100 110 120 130 140 pF1KB0 SLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL .. .:.. XP_016 TIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCG 360 370 380 390 400 410 145 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:19:12 2016 done: Sat Nov 5 17:19:13 2016 Total Scan time: 4.570 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]