FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0933, 148 aa 1>>>pF1KB0933 148 - 148 aa - 148 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7108+/-0.000274; mu= 16.5629+/- 0.017 mean_var=96.1522+/-20.120, 0's: 0 Z-trim(121.3): 211 B-trim: 1892 in 2/54 Lambda= 0.130796 statistics sampled from 37396 (37694) to 37396 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.795), E-opt: 0.2 (0.442), width: 16 Scan time: 5.500 The best scores are: opt bits E(85289) NP_009150 (OMIM: 612489) RING finger protein 24 is ( 148) 1054 207.8 5.4e-54 NP_001308678 (OMIM: 612489) RING finger protein 24 ( 148) 1054 207.8 5.4e-54 NP_001127809 (OMIM: 612489) RING finger protein 24 ( 148) 1054 207.8 5.4e-54 XP_011527448 (OMIM: 612489) PREDICTED: RING finger ( 163) 1054 207.8 5.7e-54 NP_001127810 (OMIM: 612489) RING finger protein 24 ( 169) 1054 207.8 5.9e-54 XP_016883109 (OMIM: 612489) PREDICTED: RING finger ( 169) 1054 207.8 5.9e-54 XP_011527447 (OMIM: 612489) PREDICTED: RING finger ( 169) 1054 207.8 5.9e-54 XP_016883110 (OMIM: 612489) PREDICTED: RING finger ( 169) 1054 207.8 5.9e-54 XP_016883111 (OMIM: 612489) PREDICTED: RING finger ( 137) 725 145.6 2.5e-35 XP_011527449 (OMIM: 612489) PREDICTED: RING finger ( 137) 725 145.6 2.5e-35 XP_016861149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 250) 234 53.3 2.8e-07 XP_016861145 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 234 53.3 2.9e-07 XP_016861146 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 234 53.3 2.9e-07 XP_011510678 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 234 53.3 2.9e-07 XP_005247149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 234 53.3 2.9e-07 XP_016861148 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 234 53.3 2.9e-07 XP_016861147 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 234 53.3 2.9e-07 XP_016861144 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 234 53.5 3.7e-07 XP_011510676 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 234 53.5 3.7e-07 XP_016861143 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 234 53.5 3.7e-07 NP_009213 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 234 53.5 3.7e-07 NP_899237 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 234 53.5 3.7e-07 XP_011510675 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 234 53.5 3.7e-07 NP_001307293 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 229 52.5 6.3e-07 NP_001307291 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 229 52.5 6.3e-07 NP_001307292 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 229 52.5 6.3e-07 NP_001307294 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 229 52.5 6.3e-07 NP_001307286 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 229 52.6 6.7e-07 NP_001307290 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 229 52.6 6.7e-07 NP_001307287 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 229 52.6 6.7e-07 NP_056343 (OMIM: 610431) E3 ubiquitin-protein liga ( 350) 229 52.6 6.7e-07 XP_016879916 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 350) 229 52.6 6.7e-07 NP_001307288 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 229 52.6 6.7e-07 NP_001307285 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 229 52.6 6.7e-07 NP_001307289 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 229 52.6 6.7e-07 XP_016861150 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 193) 207 48.1 8.2e-06 XP_016879917 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 227) 201 47.0 2e-05 NP_078815 (OMIM: 300439) E3 ubiquitin-protein liga ( 402) 191 45.5 0.00011 XP_016869786 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402) 191 45.5 0.00011 XP_016869785 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402) 191 45.5 0.00011 NP_919445 (OMIM: 300439) E3 ubiquitin-protein liga ( 428) 191 45.5 0.00011 NP_919313 (OMIM: 612488) E3 ubiquitin-protein liga ( 432) 191 45.5 0.00011 XP_011516014 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 191 45.5 0.00011 XP_005251423 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 191 45.5 0.00011 XP_005251425 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 191 45.5 0.00011 XP_005251424 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 191 45.5 0.00011 NP_919309 (OMIM: 612488) E3 ubiquitin-protein liga ( 432) 191 45.5 0.00011 XP_011516015 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 191 45.5 0.00011 NP_919311 (OMIM: 612488) E3 ubiquitin-protein liga ( 432) 191 45.5 0.00011 XP_006716784 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 191 45.5 0.00011 >>NP_009150 (OMIM: 612489) RING finger protein 24 isofor (148 aa) initn: 1054 init1: 1054 opt: 1054 Z-score: 1090.4 bits: 207.8 E(85289): 5.4e-54 Smith-Waterman score: 1054; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:1-148) 10 20 30 40 50 60 pF1KB0 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 KQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNM 70 80 90 100 110 120 130 140 pF1KB0 PVLQLAQLHSKQDRGPPQGPLPGAENIV :::::::::::::::::::::::::::: NP_009 PVLQLAQLHSKQDRGPPQGPLPGAENIV 130 140 >>NP_001308678 (OMIM: 612489) RING finger protein 24 iso (148 aa) initn: 1054 init1: 1054 opt: 1054 Z-score: 1090.4 bits: 207.8 E(85289): 5.4e-54 Smith-Waterman score: 1054; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:1-148) 10 20 30 40 50 60 pF1KB0 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNM 70 80 90 100 110 120 130 140 pF1KB0 PVLQLAQLHSKQDRGPPQGPLPGAENIV :::::::::::::::::::::::::::: NP_001 PVLQLAQLHSKQDRGPPQGPLPGAENIV 130 140 >>NP_001127809 (OMIM: 612489) RING finger protein 24 iso (148 aa) initn: 1054 init1: 1054 opt: 1054 Z-score: 1090.4 bits: 207.8 E(85289): 5.4e-54 Smith-Waterman score: 1054; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:1-148) 10 20 30 40 50 60 pF1KB0 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNM 70 80 90 100 110 120 130 140 pF1KB0 PVLQLAQLHSKQDRGPPQGPLPGAENIV :::::::::::::::::::::::::::: NP_001 PVLQLAQLHSKQDRGPPQGPLPGAENIV 130 140 >>XP_011527448 (OMIM: 612489) PREDICTED: RING finger pro (163 aa) initn: 1054 init1: 1054 opt: 1054 Z-score: 1089.9 bits: 207.8 E(85289): 5.7e-54 Smith-Waterman score: 1054; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:16-163) 10 20 30 40 pF1KB0 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCY ::::::::::::::::::::::::::::::::::::::::::::: XP_011 MCAEGRWKAENICSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCY 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB0 LIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCL 70 80 90 100 110 120 110 120 130 140 pF1KB0 IKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV ::::::::::::::::::::::::::::::::::::::::::: XP_011 IKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV 130 140 150 160 >>NP_001127810 (OMIM: 612489) RING finger protein 24 iso (169 aa) initn: 1054 init1: 1054 opt: 1054 Z-score: 1089.7 bits: 207.8 E(85289): 5.9e-54 Smith-Waterman score: 1054; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:22-169) 10 20 30 pF1KB0 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS ::::::::::::::::::::::::::::::::::::::: NP_001 MLNKSGESRYPALFPVLGGSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB0 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA 70 80 90 100 110 120 100 110 120 130 140 pF1KB0 FHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV 130 140 150 160 >>XP_016883109 (OMIM: 612489) PREDICTED: RING finger pro (169 aa) initn: 1054 init1: 1054 opt: 1054 Z-score: 1089.7 bits: 207.8 E(85289): 5.9e-54 Smith-Waterman score: 1054; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:22-169) 10 20 30 pF1KB0 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS ::::::::::::::::::::::::::::::::::::::: XP_016 MLNKSGESRYPALFPVLGGSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB0 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA 70 80 90 100 110 120 100 110 120 130 140 pF1KB0 FHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV 130 140 150 160 >>XP_011527447 (OMIM: 612489) PREDICTED: RING finger pro (169 aa) initn: 1054 init1: 1054 opt: 1054 Z-score: 1089.7 bits: 207.8 E(85289): 5.9e-54 Smith-Waterman score: 1054; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:22-169) 10 20 30 pF1KB0 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS ::::::::::::::::::::::::::::::::::::::: XP_011 MLNKSGESRYPALFPVLGGSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB0 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA 70 80 90 100 110 120 100 110 120 130 140 pF1KB0 FHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV 130 140 150 160 >>XP_016883110 (OMIM: 612489) PREDICTED: RING finger pro (169 aa) initn: 1054 init1: 1054 opt: 1054 Z-score: 1089.7 bits: 207.8 E(85289): 5.9e-54 Smith-Waterman score: 1054; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:22-169) 10 20 30 pF1KB0 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS ::::::::::::::::::::::::::::::::::::::: XP_016 MLNKSGESRYPALFPVLGGSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB0 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA 70 80 90 100 110 120 100 110 120 130 140 pF1KB0 FHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV 130 140 150 160 >>XP_016883111 (OMIM: 612489) PREDICTED: RING finger pro (137 aa) initn: 725 init1: 725 opt: 725 Z-score: 755.2 bits: 145.6 E(85289): 2.5e-35 Smith-Waterman score: 725; 100.0% identity (100.0% similar) in 103 aa overlap (1-103:22-124) 10 20 30 pF1KB0 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS ::::::::::::::::::::::::::::::::::::::: XP_016 MLNKSGESRYPALFPVLGGSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB0 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA 70 80 90 100 110 120 100 110 120 130 140 pF1KB0 FHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV :::: XP_016 FHRKAVPDKLDGFMIGL 130 >>XP_011527449 (OMIM: 612489) PREDICTED: RING finger pro (137 aa) initn: 725 init1: 725 opt: 725 Z-score: 755.2 bits: 145.6 E(85289): 2.5e-35 Smith-Waterman score: 725; 100.0% identity (100.0% similar) in 103 aa overlap (1-103:22-124) 10 20 30 pF1KB0 MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS ::::::::::::::::::::::::::::::::::::::: XP_011 MLNKSGESRYPALFPVLGGSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB0 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHELCAVCLEDFKPRDELGICPCKHA 70 80 90 100 110 120 100 110 120 130 140 pF1KB0 FHRKCLIKWLEVRKVCPLCNMPVLQLAQLHSKQDRGPPQGPLPGAENIV :::: XP_011 FHRKAVPDKLDGFMIGL 130 148 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:19:45 2016 done: Sat Nov 5 17:19:46 2016 Total Scan time: 5.500 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]