FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0934, 381 aa 1>>>pF1KB0934 381 - 381 aa - 381 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9852+/-0.00092; mu= 9.2097+/- 0.056 mean_var=120.8819+/-24.284, 0's: 0 Z-trim(108.9): 90 B-trim: 67 in 1/52 Lambda= 0.116652 statistics sampled from 10405 (10507) to 10405 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.323), width: 16 Scan time: 2.820 The best scores are: opt bits E(32554) CCDS3146.1 RNF13 gene_id:11342|Hs108|chr3 ( 381) 2526 436.2 2.3e-122 CCDS11060.1 RNF167 gene_id:26001|Hs108|chr17 ( 350) 1104 196.8 2.4e-50 CCDS82040.1 RNF167 gene_id:26001|Hs108|chr17 ( 315) 1081 193.0 3.2e-49 CCDS42475.1 ZNRF4 gene_id:148066|Hs108|chr19 ( 429) 756 138.3 1.2e-32 >>CCDS3146.1 RNF13 gene_id:11342|Hs108|chr3 (381 aa) initn: 2526 init1: 2526 opt: 2526 Z-score: 2310.2 bits: 436.2 E(32554): 2.3e-122 Smith-Waterman score: 2526; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381) 10 20 30 40 50 60 pF1KB0 MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 AEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 AEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 VHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHLILVPEFSLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHLILVPEFSLPL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 EYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 AICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 AICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSSQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 EENEVTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDYEEDDNEDTDSSDAENEINE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EENEVTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDYEEDDNEDTDSSDAENEINE 310 320 330 340 350 360 370 380 pF1KB0 HDVVVQLQPNGERDYNIANTV ::::::::::::::::::::: CCDS31 HDVVVQLQPNGERDYNIANTV 370 380 >>CCDS11060.1 RNF167 gene_id:26001|Hs108|chr17 (350 aa) initn: 1106 init1: 1085 opt: 1104 Z-score: 1017.4 bits: 196.8 E(32554): 2.4e-50 Smith-Waterman score: 1112; 53.3% identity (79.7% similar) in 306 aa overlap (31-327:21-325) 10 20 30 40 50 60 pF1KB0 MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLP :... : : . .:::. : :::: :: : CCDS11 MHPAAFPLPVVVAAVLWGAAPTRGLIRATSDHNASMDFADLPALFGATLS 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 AEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAI :::.:::....:.::: ::.::: ....::.:.::.:::::.::::::.::: ::. CCDS11 QEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB0 VHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHLILVPEFSLPL ::::.:..:..: :. :. ..: :::::::: :.. :. :.::::....:::. ..:: CCDS11 VHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNTFPL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB0 EYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVC :::::: :::. .. . ::.. .: :.: .:::: :.:::..:.: ..:::.:::: CCDS11 GYYLIPFTGIVGLLVLAMGAVMIARCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDVC 180 190 200 210 220 230 250 260 270 280 290 pF1KB0 AICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSS- ::::::::::::::.:::.:::: .:::::::.:.::::.::: : . :: :.. ... CCDS11 AICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 QEENE--------VTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDYEEDDNEDTDS :::.. ..:.:::: .. . :::.:. CCDS11 QEEGDEGEPRDHPASERTPLLGSSPTLPT-SFGSLAPAPLVFPGPSTDPPLSPPSSPVIL 300 310 320 330 340 360 370 380 pF1KB0 SDAENEINEHDVVVQLQPNGERDYNIANTV CCDS11 V 350 >>CCDS82040.1 RNF167 gene_id:26001|Hs108|chr17 (315 aa) initn: 1084 init1: 1063 opt: 1081 Z-score: 997.1 bits: 193.0 E(32554): 3.2e-49 Smith-Waterman score: 1089; 54.3% identity (80.3% similar) in 289 aa overlap (48-327:3-290) 20 30 40 50 60 70 pF1KB0 ILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGLKGFLINSKPENAC : :::: :: : :::.:::....:.::: CCDS82 MDFADLPALFGATLSQEGLQGFLVEAHPDNAC 10 20 30 80 90 100 110 120 130 pF1KB0 EPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDI ::.::: ....::.:.::.:::::.::::::.::: ::.::::.:..:..: :. CCDS82 SPIAPPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB0 EVLKKIDIPSVFIGESSANSLKDEFTYEKGGHLILVPEFSLPLEYYLIPFLIIVGICLIL :. ..: :::::::: :.. :. :.::::....:::. ..:: :::::: :::. .. CCDS82 EIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNTFPLGYYLIPFTGIVGLLVLA 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB0 IVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILP . ::.. .: :.: .:::: :.:::..:.: ..:::.::::::::::::::::::.:: CCDS82 MGAVMIARCIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP 160 170 180 190 200 210 260 270 280 290 300 pF1KB0 CSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSS-QEENE--------VTEH :.:::: .:::::::.:.::::.::: : . :: :.. ... :::.. ..:. CCDS82 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEGDEGEPRDHPASER 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB0 TPLLRPLASVSAQSFGALSESRSHQNMTESSDYEEDDNEDTDSSDAENEINEHDVVVQLQ :::: .. . :::.:. CCDS82 TPLLGSSPTLPT-SFGSLAPAPLVFPGPSTDPPLSPPSSPVILV 280 290 300 310 >>CCDS42475.1 ZNRF4 gene_id:148066|Hs108|chr19 (429 aa) initn: 620 init1: 281 opt: 756 Z-score: 699.5 bits: 138.3 E(32554): 1.2e-32 Smith-Waterman score: 756; 41.1% identity (69.0% similar) in 316 aa overlap (18-321:80-389) 10 20 30 40 pF1KB0 MLLSIGMLMLSATQVYTILTVQLFAFLNLL--PVEADILAYNFENAS ...:. . :.:: :..: . : .:.: CCDS42 KASCLPPPVGPSSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSS 50 60 70 80 90 100 50 60 70 80 90 100 pF1KB0 QT-FDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNF .. : :::: :: : ::..:.:.. :: :::.:: : . . : :. :::::: ::.: CCDS42 SVDFADLPALFGVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGA-IVLIRRYDCTF 110 120 130 140 150 160 110 120 130 140 150 160 pF1KB0 DIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTY :.:::::::::..::::::: ::::.:: .. .: :::::..:.....:. . CCDS42 DLKVLNAQRAGFEAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGC 170 180 190 200 210 220 170 180 190 200 210 pF1KB0 EKGGHLILVPEFSLPLEYYLIPFLII---VGICLILIV-IFMITKFVQDRHRA---RRNR .:..: .:.:. . : : . .: : :.: :.. . . .: .: CCDS42 NKSAHALLLPDDPPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRP 230 240 250 260 270 280 220 230 240 250 260 270 pF1KB0 LRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKT-KK .. . .: :. : . :.:::::::::.::.:.::::::.:::::.:::.... .. CCDS42 VKTSTCQKAQVRTFTWHN--DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRR 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB0 TCPVCKQKVVPSQGDSDSDTDSSQEENE-VTEHTPLLRPLASVSAQSFGALSESRSHQNM .::::::.:. .. . :: : : ..:. . : : :. ....: CCDS42 SCPVCKQSVAATEDSFDSTTYSFRDEDPSLPGHRP---PIWAIQVQLRSRRLELLGRASP 350 360 370 380 390 400 340 350 360 370 380 pF1KB0 TESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV CCDS42 HCHCSTTSLEAEYTTVSSAPPEAPGQ 410 420 381 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:26:29 2016 done: Sat Nov 5 21:26:30 2016 Total Scan time: 2.820 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]