FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0940, 390 aa 1>>>pF1KB0940 390 - 390 aa - 390 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3547+/-0.000348; mu= 13.8689+/- 0.022 mean_var=128.0414+/-26.487, 0's: 0 Z-trim(119.2): 130 B-trim: 1732 in 2/50 Lambda= 0.113344 statistics sampled from 32714 (32874) to 32714 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.385), width: 16 Scan time: 9.320 The best scores are: opt bits E(85289) NP_002389 (OMIM: 601739) homeobox protein Meis1 [H ( 390) 2740 459.0 8.7e-129 XP_005264380 (OMIM: 601739) PREDICTED: homeobox pr ( 406) 2714 454.8 1.7e-127 XP_005264379 (OMIM: 601739) PREDICTED: homeobox pr ( 465) 2601 436.3 6.9e-122 XP_005264378 (OMIM: 601739) PREDICTED: homeobox pr ( 481) 2575 432.1 1.3e-120 NP_733774 (OMIM: 601740) homeobox protein Meis2 is ( 394) 2377 399.6 6.5e-111 XP_016859631 (OMIM: 601739) PREDICTED: homeobox pr ( 417) 2377 399.7 6.7e-111 XP_006720588 (OMIM: 601740) PREDICTED: homeobox pr ( 393) 2351 395.4 1.2e-109 XP_016859630 (OMIM: 601739) PREDICTED: homeobox pr ( 433) 2351 395.4 1.3e-109 NP_002390 (OMIM: 601740) homeobox protein Meis2 is ( 381) 2284 384.4 2.4e-106 NP_733776 (OMIM: 601740) homeobox protein Meis2 is ( 470) 2250 379.0 1.3e-104 NP_001207411 (OMIM: 601740) homeobox protein Meis2 ( 470) 2250 379.0 1.3e-104 XP_005264382 (OMIM: 601739) PREDICTED: homeobox pr ( 325) 2163 364.6 1.9e-100 NP_733777 (OMIM: 601740) homeobox protein Meis2 is ( 401) 2074 350.1 5.4e-96 NP_733775 (OMIM: 601740) homeobox protein Meis2 is ( 477) 2074 350.2 6.1e-96 XP_006720587 (OMIM: 601740) PREDICTED: homeobox pr ( 400) 2048 345.9 1e-94 XP_006720586 (OMIM: 601740) PREDICTED: homeobox pr ( 476) 2048 345.9 1.2e-94 XP_005264381 (OMIM: 601739) PREDICTED: homeobox pr ( 400) 2024 341.9 1.6e-93 NP_758526 (OMIM: 601740) homeobox protein Meis2 is ( 388) 1981 334.9 2e-91 NP_758527 (OMIM: 601740) homeobox protein Meis2 is ( 306) 1879 318.1 1.8e-86 XP_016877694 (OMIM: 601740) PREDICTED: homeobox pr ( 306) 1879 318.1 1.8e-86 XP_016859632 (OMIM: 601739) PREDICTED: homeobox pr ( 352) 1800 305.3 1.5e-82 XP_016859635 (OMIM: 601739) PREDICTED: homeobox pr ( 246) 1729 293.5 3.6e-79 XP_006720589 (OMIM: 601740) PREDICTED: homeobox pr ( 389) 1720 292.2 1.4e-78 XP_016859634 (OMIM: 601739) PREDICTED: homeobox pr ( 321) 1590 270.9 3.1e-72 XP_016859633 (OMIM: 601739) PREDICTED: homeobox pr ( 321) 1590 270.9 3.1e-72 XP_006720592 (OMIM: 601740) PREDICTED: homeobox pr ( 255) 1477 252.3 9.5e-67 XP_006720590 (OMIM: 601740) PREDICTED: homeobox pr ( 331) 1342 230.3 5.1e-60 XP_011519893 (OMIM: 601740) PREDICTED: homeobox pr ( 331) 1342 230.3 5.1e-60 NP_001307623 (OMIM: 602100) homeobox protein PKNOX ( 435) 459 86.1 1.8e-16 XP_016873601 (OMIM: 613066) PREDICTED: homeobox pr ( 327) 453 85.0 2.9e-16 XP_011541248 (OMIM: 613066) PREDICTED: homeobox pr ( 356) 453 85.0 3.1e-16 NP_004562 (OMIM: 602100) homeobox protein PKNOX1 i ( 436) 443 83.4 1.1e-15 XP_011541249 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 386 74.0 5.9e-13 XP_006718957 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 386 74.0 5.9e-13 XP_016873600 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 386 74.0 5.9e-13 XP_005271700 (OMIM: 613066) PREDICTED: homeobox pr ( 443) 386 74.1 7.1e-13 XP_016873599 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 386 74.2 7.5e-13 XP_011541246 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 386 74.2 7.5e-13 NP_071345 (OMIM: 613066) homeobox protein PKNOX2 [ ( 472) 386 74.2 7.5e-13 XP_011541247 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 386 74.2 7.5e-13 XP_005271699 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 386 74.2 7.5e-13 NP_001273187 (OMIM: 602100) homeobox protein PKNOX ( 319) 375 72.2 2e-12 NP_620410 (OMIM: 300411) homeobox protein TGIF2LX ( 241) 258 52.9 9.2e-07 NP_631960 (OMIM: 400025) homeobox protein TGIF2LY ( 185) 252 51.9 1.5e-06 NP_775299 (OMIM: 142946,602630) homeobox protein T ( 286) 247 51.2 3.6e-06 NP_068581 (OMIM: 607294) homeobox protein TGIF2 [H ( 237) 245 50.8 4e-06 NP_001186444 (OMIM: 607294) homeobox protein TGIF2 ( 237) 245 50.8 4e-06 NP_001186442 (OMIM: 607294) homeobox protein TGIF2 ( 237) 245 50.8 4e-06 NP_001186443 (OMIM: 607294) homeobox protein TGIF2 ( 237) 245 50.8 4e-06 XP_016881447 (OMIM: 142946,602630) PREDICTED: home ( 272) 239 49.9 8.7e-06 >>NP_002389 (OMIM: 601739) homeobox protein Meis1 [Homo (390 aa) initn: 2740 init1: 2740 opt: 2740 Z-score: 2433.1 bits: 459.0 E(85289): 8.7e-129 Smith-Waterman score: 2740; 100.0% identity (100.0% similar) in 390 aa overlap (1-390:1-390) 10 20 30 40 50 60 pF1KB0 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAMA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 PSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 IAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 MPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 GDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 SEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMGGFVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMGGFVM 310 320 330 340 350 360 370 380 390 pF1KB0 DGQQHMGIRAPGPMSGMGMNMGMEGQWHYM :::::::::::::::::::::::::::::: NP_002 DGQQHMGIRAPGPMSGMGMNMGMEGQWHYM 370 380 390 >>XP_005264380 (OMIM: 601739) PREDICTED: homeobox protei (406 aa) initn: 2714 init1: 2714 opt: 2714 Z-score: 2409.9 bits: 454.8 E(85289): 1.7e-127 Smith-Waterman score: 2714; 100.0% identity (100.0% similar) in 386 aa overlap (5-390:21-406) 10 20 30 40 pF1KB0 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPP :::::::::::::::::::::::::::::::::::::::: XP_005 MAQRRKMESCAFAFEFALNLYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB0 LHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREP 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB0 GVAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB0 LCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB0 SGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVAT 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB0 NIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQ 310 320 330 340 350 360 350 360 370 380 390 pF1KB0 GTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM :::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM 370 380 390 400 >>XP_005264379 (OMIM: 601739) PREDICTED: homeobox protei (465 aa) initn: 2599 init1: 2599 opt: 2601 Z-score: 2309.3 bits: 436.3 E(85289): 6.9e-122 Smith-Waterman score: 2603; 96.4% identity (96.9% similar) in 392 aa overlap (1-382:1-392) 10 20 30 40 50 60 pF1KB0 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAMA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 PSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 IAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 MPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 GDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 SEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMGGFVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMGGFVM 310 320 330 340 350 360 370 380 390 pF1KB0 DGQQHMGIRAPG--PMSG--------MGMNMGMEGQWHYM :::::::::::: : : ::..:: XP_005 DGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSYTQPQMPPHPAQLRHGPPMHTYIPG 370 380 390 400 410 420 XP_005 HPHHPTVMMHGGPPHPGMPMSASSPTVLNTGDPTMSGQVMDIHAQ 430 440 450 460 >>XP_005264378 (OMIM: 601739) PREDICTED: homeobox protei (481 aa) initn: 2573 init1: 2573 opt: 2575 Z-score: 2286.1 bits: 432.1 E(85289): 1.3e-120 Smith-Waterman score: 2577; 96.4% identity (96.9% similar) in 388 aa overlap (5-382:21-408) 10 20 30 40 pF1KB0 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPP :::::::::::::::::::::::::::::::::::::::: XP_005 MAQRRKMESCAFAFEFALNLYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB0 LHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREP 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB0 GVAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB0 LCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB0 SGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVAT 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB0 NIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQ 310 320 330 340 350 360 350 360 370 380 390 pF1KB0 GTPYNPDGQPMGGFVMDGQQHMGIRAPG--PMSG--------MGMNMGMEGQWHYM :::::::::::::::::::::::::::: : : ::..:: XP_005 GTPYNPDGQPMGGFVMDGQQHMGIRAPGLQSMPGEYVARGGPMGVSMGQPSYTQPQMPPH 370 380 390 400 410 420 XP_005 PAQLRHGPPMHTYIPGHPHHPTVMMHGGPPHPGMPMSASSPTVLNTGDPTMSGQVMDIHA 430 440 450 460 470 480 >>NP_733774 (OMIM: 601740) homeobox protein Meis2 isofor (394 aa) initn: 1443 init1: 1141 opt: 2377 Z-score: 2112.3 bits: 399.6 E(85289): 6.5e-111 Smith-Waterman score: 2377; 85.8% identity (94.9% similar) in 394 aa overlap (1-390:1-394) 10 20 30 40 50 pF1KB0 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQY--PHTAHTNA ::::::.:::::::::::.:..::::::: : . ::::::::::::. :. :. : :. NP_733 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 MAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFN : ::::.:::::::::::::::::::::::.::::::::::::::::::::::::.::: NP_733 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 EDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: NP_733 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 GKMPIDLVIDDREGGSKSDSEDIT-RSANLTDQ-PSWNRDHDDTASTRSGGTPGPSSGGH ::::::::::.:.:.:::: :... :.::.:. :: :::::..::.:.:::::::::: NP_733 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 TSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLT .:.:::::::::::::::::::.:::::::::::::.::::::::::::::::::::::: NP_733 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMG :::::::::::::::::::::::::::::::::::::::::::::::::. :.:.::::: NP_733 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMG 310 320 330 340 350 360 360 370 380 390 pF1KB0 GFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM .::.::::::::: ::::::::::::.:::::: NP_733 SFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM 370 380 390 >>XP_016859631 (OMIM: 601739) PREDICTED: homeobox protei (417 aa) initn: 2726 init1: 2367 opt: 2377 Z-score: 2111.9 bits: 399.7 E(85289): 6.7e-111 Smith-Waterman score: 2676; 93.5% identity (93.5% similar) in 417 aa overlap (1-390:1-417) 10 20 30 40 50 60 pF1KB0 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAMA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 PSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNED 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 IAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 MPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTRSGGTPGPSSGGHTSHS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 GDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYP 250 260 270 280 290 300 310 320 330 340 pF1KB0 SEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRA------------------- ::::::::::::::::::::::::::::::::::::::::: XP_016 SEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGKSPIVTVFKSRKRKPSSS 310 320 330 340 350 360 350 360 370 380 390 pF1KB0 --------VSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSPGGPLPVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM 370 380 390 400 410 >>XP_006720588 (OMIM: 601740) PREDICTED: homeobox protei (393 aa) initn: 1417 init1: 1141 opt: 2351 Z-score: 2089.3 bits: 395.4 E(85289): 1.2e-109 Smith-Waterman score: 2351; 85.6% identity (94.9% similar) in 390 aa overlap (5-390:4-393) 10 20 30 40 50 pF1KB0 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQY--PHTAHTNA ::.:::::::::::.:..::::::: : . ::::::::::::. :. :. : :. XP_006 MFLYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 MAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFN : ::::.:::::::::::::::::::::::.::::::::::::::::::::::::.::: XP_006 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 EDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 GKMPIDLVIDDREGGSKSDSEDIT-RSANLTDQ-PSWNRDHDDTASTRSGGTPGPSSGGH ::::::::::.:.:.:::: :... :.::.:. :: :::::..::.:.:::::::::: XP_006 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 TSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLT .:.:::::::::::::::::::.:::::::::::::.::::::::::::::::::::::: XP_006 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMG :::::::::::::::::::::::::::::::::::::::::::::::::. :.:.::::: XP_006 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMG 300 310 320 330 340 350 360 370 380 390 pF1KB0 GFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM .::.::::::::: ::::::::::::.:::::: XP_006 SFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM 360 370 380 390 >>XP_016859630 (OMIM: 601739) PREDICTED: homeobox protei (433 aa) initn: 2700 init1: 2341 opt: 2351 Z-score: 2088.8 bits: 395.4 E(85289): 1.3e-109 Smith-Waterman score: 2650; 93.5% identity (93.5% similar) in 413 aa overlap (5-390:21-433) 10 20 30 40 pF1KB0 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPP :::::::::::::::::::::::::::::::::::::::: XP_016 MAQRRKMESCAFAFEFALNLYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB0 LHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREP 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB0 GVAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVAGGDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB0 LCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDITRSANLTDQPSWNRDHDDTASTR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB0 SGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVAT 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB0 NIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRA--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGKS 310 320 330 340 350 360 350 360 370 pF1KB0 ------------------------VSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGM :::::::::::::::::::::::::::::::::::: XP_016 PIVTVFKSRKRKPSSSHSPGGPLPVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGM 370 380 390 400 410 420 380 390 pF1KB0 GMNMGMEGQWHYM ::::::::::::: XP_016 GMNMGMEGQWHYM 430 >>NP_002390 (OMIM: 601740) homeobox protein Meis2 isofor (381 aa) initn: 1350 init1: 1141 opt: 2284 Z-score: 2030.3 bits: 384.4 E(85289): 2.4e-106 Smith-Waterman score: 2284; 85.6% identity (94.8% similar) in 381 aa overlap (14-390:1-381) 10 20 30 40 50 pF1KB0 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQY--PHTAHTNA :::::.:..::::::: : . ::::::::::::. :. :. : :. NP_002 MDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV 10 20 30 40 60 70 80 90 100 110 pF1KB0 MAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFN : ::::.:::::::::::::::::::::::.::::::::::::::::::::::::.::: NP_002 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB0 EDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB0 GKMPIDLVIDDREGGSKSDSEDIT-RSANLTDQ-PSWNRDHDDTASTRSGGTPGPSSGGH ::::::::::.:.:.:::: :... :.::.:. :: :::::..::.:.:::::::::: NP_002 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB0 TSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLT .:.:::::::::::::::::::.:::::::::::::.::::::::::::::::::::::: NP_002 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB0 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMG :::::::::::::::::::::::::::::::::::::::::::::::::. :.:.::::: NP_002 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMG 290 300 310 320 330 340 360 370 380 390 pF1KB0 GFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM .::.::::::::: ::::::::::::.:::::: NP_002 SFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM 350 360 370 380 >>NP_733776 (OMIM: 601740) homeobox protein Meis2 isofor (470 aa) initn: 2273 init1: 1004 opt: 2250 Z-score: 1999.0 bits: 379.0 E(85289): 1.3e-104 Smith-Waterman score: 2250; 83.0% identity (92.6% similar) in 393 aa overlap (1-383:1-393) 10 20 30 40 50 pF1KB0 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQY--PHTAHTNA ::::::.:::::::::::.:..::::::: : . ::::::::::::. :. :. : :. NP_733 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 MAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFN : ::::.:::::::::::::::::::::::.::::::::::::::::::::::::.::: NP_733 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 EDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: NP_733 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB0 GKMPIDLVIDDREGGSKSDSEDIT-RSANLTDQ-PSWNRDHDDTASTRSGGTPGPSSGGH ::::::::::.:.:.:::: :... :.::.:. :: :::::..::.:.:::::::::: NP_733 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB0 TSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLT .:.:::::::::::::::::::.:::::::::::::.::::::::::::::::::::::: NP_733 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPDGQPMG :::::::::::::::::::::::::::::::::::::::::::::::::. :.:.::::: NP_733 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMG 310 320 330 340 350 360 360 370 380 390 pF1KB0 GFVMDGQQHMGIRA------PGPMSGMGMNMGMEGQWHYM .::.::::::::: :: . ..: ::: NP_733 SFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLRHGPPMHS 370 380 390 400 410 420 NP_733 YLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ 430 440 450 460 470 390 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:21:57 2016 done: Sat Nov 5 17:21:59 2016 Total Scan time: 9.320 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]