Result of FASTA (omim) for pF1KB0942
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0942, 392 aa
  1>>>pF1KB0942 392 - 392 aa - 392 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.7762+/-0.000414; mu= 11.0795+/- 0.026
 mean_var=166.4084+/-34.758, 0's: 0 Z-trim(115.5): 266  B-trim: 1159 in 1/55
 Lambda= 0.099423
 statistics sampled from 25611 (25956) to 25611 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.304), width:  16
 Scan time:  8.940

The best scores are:                                      opt bits E(85289)
NP_060376 (OMIM: 607811) p21-activated protein kin ( 392) 2605 386.0 8.1e-107
XP_005249261 (OMIM: 607811) PREDICTED: p21-activat ( 393) 2593 384.3 2.7e-106
XP_011513022 (OMIM: 607811) PREDICTED: p21-activat ( 415) 2405 357.4 3.6e-98
XP_011513023 (OMIM: 607811) PREDICTED: p21-activat ( 414) 2401 356.8 5.4e-98
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334)  264 50.2 8.8e-06
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334)  264 50.2 8.8e-06
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334)  264 50.2 8.8e-06
XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 ( 246)  232 45.4 0.00017
XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 ( 246)  232 45.4 0.00017
XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 ( 246)  232 45.4 0.00017
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300)  230 45.3 0.00024
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321)  230 45.3 0.00025
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326)  230 45.3 0.00025
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359)  230 45.3 0.00027
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369)  230 45.3 0.00028
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374)  230 45.4 0.00028
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407)  230 45.4 0.00029
NP_001269467 (OMIM: 139380,613065,616973) guanine  ( 240)  224 44.3 0.00037
XP_016856549 (OMIM: 139380,613065,616973) PREDICTE ( 340)  224 44.4 0.00047
NP_002065 (OMIM: 139380,613065,616973) guanine nuc ( 340)  224 44.4 0.00047
XP_016856548 (OMIM: 139380,613065,616973) PREDICTE ( 340)  224 44.4 0.00047
XP_016856550 (OMIM: 139380,613065,616973) PREDICTE ( 340)  224 44.4 0.00047
NP_001269468 (OMIM: 139380,613065,616973) guanine  ( 340)  224 44.4 0.00047
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540)  226 45.0 0.00053
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589)  226 45.0 0.00056
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627)  226 45.0 0.00059
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  226 45.1 0.00062
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  226 45.1 0.00062
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  226 45.1 0.00064
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  226 45.1 0.00064
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707)  226 45.1 0.00064
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  226 45.1 0.00064
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  226 45.1 0.00064
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655)  222 44.5  0.0009
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655)  222 44.5  0.0009
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655)  222 44.5  0.0009
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658)  222 44.5  0.0009
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672)  222 44.5 0.00091
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672)  222 44.5 0.00091
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672)  222 44.5 0.00091
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675)  222 44.5 0.00092
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675)  222 44.5 0.00092
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675)  222 44.5 0.00092
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675)  222 44.5 0.00092
NP_006373 (OMIM: 604596) CMT1A duplicated region t ( 752)  216 43.7  0.0018
NP_001246 (OMIM: 603618) cell division cycle prote ( 499)  213 43.1  0.0018
XP_011535412 (OMIM: 601686) PREDICTED: telomerase  (2104)  220 44.7  0.0024
XP_016863001 (OMIM: 606990) PREDICTED: coatomer su ( 877)  213 43.3  0.0027
NP_001305964 (OMIM: 601686) telomerase protein com (2519)  220 44.8  0.0027
NP_004757 (OMIM: 606990) coatomer subunit beta' [H ( 906)  213 43.3  0.0027


>>NP_060376 (OMIM: 607811) p21-activated protein kinase-  (392 aa)
 initn: 2605 init1: 2605 opt: 2605  Z-score: 2038.7  bits: 386.0 E(85289): 8.1e-107
Smith-Waterman score: 2605; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392)

               10        20        30        40        50        60
pF1KB0 MELVAGCYEQVLFGFAVHPEPEACGDHEQWTLVADFTHHAHTASLSAVAVNSRFVVTGSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MELVAGCYEQVLFGFAVHPEPEACGDHEQWTLVADFTHHAHTASLSAVAVNSRFVVTGSK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 DETIHIYDMKKKIEHGALVHHSGTITCLKFYGNRHLISGAEDGLICIWDAKKWECLKSIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DETIHIYDMKKKIEHGALVHHSGTITCLKFYGNRHLISGAEDGLICIWDAKKWECLKSIK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 AHKGQVTFLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPRGEQYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AHKGQVTFLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPRGEQYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 VIIQNKIDIYQLDTASISGTITNEKRISSVKFLSESVLAVAGDEEVIRFFDCDSLVCLCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VIIQNKIDIYQLDTASISGTITNEKRISSVKFLSESVLAVAGDEEVIRFFDCDSLVCLCE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 FKAHENRVKDMFSFEIPEHHVIVSASSDGFIKMWKLKQDKKVPPSLLCEINTNARLTCLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FKAHENRVKDMFSFEIPEHHVIVSASSDGFIKMWKLKQDKKVPPSLLCEINTNARLTCLG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 VWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPGDTVHKEEKRSKPNTKKRGLTGDSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPGDTVHKEEKRSKPNTKKRGLTGDSKK
              310       320       330       340       350       360

              370       380       390  
pF1KB0 ATKESGLISTKKRKMVEMLEKKRKKKKIKTMQ
       ::::::::::::::::::::::::::::::::
NP_060 ATKESGLISTKKRKMVEMLEKKRKKKKIKTMQ
              370       380       390  

>>XP_005249261 (OMIM: 607811) PREDICTED: p21-activated p  (393 aa)
 initn: 2401 init1: 2401 opt: 2593  Z-score: 2029.4  bits: 384.3 E(85289): 2.7e-106
Smith-Waterman score: 2593; 99.7% identity (99.7% similar) in 393 aa overlap (1-392:1-393)

               10        20         30        40        50         
pF1KB0 MELVAGCYEQVLFGFAVHPEPEACGDHEQ-WTLVADFTHHAHTASLSAVAVNSRFVVTGS
       ::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
XP_005 MELVAGCYEQVLFGFAVHPEPEACGDHEQQWTLVADFTHHAHTASLSAVAVNSRFVVTGS
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB0 KDETIHIYDMKKKIEHGALVHHSGTITCLKFYGNRHLISGAEDGLICIWDAKKWECLKSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDETIHIYDMKKKIEHGALVHHSGTITCLKFYGNRHLISGAEDGLICIWDAKKWECLKSI
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB0 KAHKGQVTFLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPRGEQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAHKGQVTFLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPRGEQY
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB0 VVIIQNKIDIYQLDTASISGTITNEKRISSVKFLSESVLAVAGDEEVIRFFDCDSLVCLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVIIQNKIDIYQLDTASISGTITNEKRISSVKFLSESVLAVAGDEEVIRFFDCDSLVCLC
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB0 EFKAHENRVKDMFSFEIPEHHVIVSASSDGFIKMWKLKQDKKVPPSLLCEINTNARLTCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFKAHENRVKDMFSFEIPEHHVIVSASSDGFIKMWKLKQDKKVPPSLLCEINTNARLTCL
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB0 GVWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPGDTVHKEEKRSKPNTKKRGLTGDSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPGDTVHKEEKRSKPNTKKRGLTGDSK
              310       320       330       340       350       360

     360       370       380       390  
pF1KB0 KATKESGLISTKKRKMVEMLEKKRKKKKIKTMQ
       :::::::::::::::::::::::::::::::::
XP_005 KATKESGLISTKKRKMVEMLEKKRKKKKIKTMQ
              370       380       390   

>>XP_011513022 (OMIM: 607811) PREDICTED: p21-activated p  (415 aa)
 initn: 2402 init1: 2402 opt: 2405  Z-score: 1883.4  bits: 357.4 E(85289): 3.6e-98
Smith-Waterman score: 2405; 95.3% identity (96.9% similar) in 387 aa overlap (6-392:31-415)

                                        10        20        30     
pF1KB0                          MELVAGCYEQVLFGFAVHPEPEACGDHEQWTLVAD
                                     : :   .::  .:   .  . ..:::::::
XP_011 MLSSNPVKQYLNCSRTSRRQNPSASEFKKEGLYSAGIFG-KTHVSNNQ-APQQQWTLVAD
               10        20        30         40         50        

          40        50        60        70        80        90     
pF1KB0 FTHHAHTASLSAVAVNSRFVVTGSKDETIHIYDMKKKIEHGALVHHSGTITCLKFYGNRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTHHAHTASLSAVAVNSRFVVTGSKDETIHIYDMKKKIEHGALVHHSGTITCLKFYGNRH
       60        70        80        90       100       110        

         100       110       120       130       140       150     
pF1KB0 LISGAEDGLICIWDAKKWECLKSIKAHKGQVTFLSIHPSGKLALSVGTDKTLRTWNLVEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LISGAEDGLICIWDAKKWECLKSIKAHKGQVTFLSIHPSGKLALSVGTDKTLRTWNLVEG
      120       130       140       150       160       170        

         160       170       180       190       200       210     
pF1KB0 RSAFIKNIKQNAHIVEWSPRGEQYVVIIQNKIDIYQLDTASISGTITNEKRISSVKFLSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSAFIKNIKQNAHIVEWSPRGEQYVVIIQNKIDIYQLDTASISGTITNEKRISSVKFLSE
      180       190       200       210       220       230        

         220       230       240       250       260       270     
pF1KB0 SVLAVAGDEEVIRFFDCDSLVCLCEFKAHENRVKDMFSFEIPEHHVIVSASSDGFIKMWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVLAVAGDEEVIRFFDCDSLVCLCEFKAHENRVKDMFSFEIPEHHVIVSASSDGFIKMWK
      240       250       260       270       280       290        

         280       290       300       310       320       330     
pF1KB0 LKQDKKVPPSLLCEINTNARLTCLGVWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKQDKKVPPSLLCEINTNARLTCLGVWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPG
      300       310       320       330       340       350        

         340       350       360       370       380       390  
pF1KB0 DTVHKEEKRSKPNTKKRGLTGDSKKATKESGLISTKKRKMVEMLEKKRKKKKIKTMQ
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTVHKEEKRSKPNTKKRGLTGDSKKATKESGLISTKKRKMVEMLEKKRKKKKIKTMQ
      360       370       380       390       400       410     

>>XP_011513023 (OMIM: 607811) PREDICTED: p21-activated p  (414 aa)
 initn: 2401 init1: 2401 opt: 2401  Z-score: 1880.3  bits: 356.8 E(85289): 5.4e-98
Smith-Waterman score: 2401; 99.7% identity (100.0% similar) in 365 aa overlap (28-392:50-414)

                  10        20        30        40        50       
pF1KB0    MELVAGCYEQVLFGFAVHPEPEACGDHEQWTLVADFTHHAHTASLSAVAVNSRFVVT
                                     .:::::::::::::::::::::::::::::
XP_011 QNPSASEFKKEGLYSAGIFGKTHVSNNQAPQQWTLVADFTHHAHTASLSAVAVNSRFVVT
      20        30        40        50        60        70         

        60        70        80        90       100       110       
pF1KB0 GSKDETIHIYDMKKKIEHGALVHHSGTITCLKFYGNRHLISGAEDGLICIWDAKKWECLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSKDETIHIYDMKKKIEHGALVHHSGTITCLKFYGNRHLISGAEDGLICIWDAKKWECLK
      80        90       100       110       120       130         

       120       130       140       150       160       170       
pF1KB0 SIKAHKGQVTFLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPRGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIKAHKGQVTFLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPRGE
     140       150       160       170       180       190         

       180       190       200       210       220       230       
pF1KB0 QYVVIIQNKIDIYQLDTASISGTITNEKRISSVKFLSESVLAVAGDEEVIRFFDCDSLVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYVVIIQNKIDIYQLDTASISGTITNEKRISSVKFLSESVLAVAGDEEVIRFFDCDSLVC
     200       210       220       230       240       250         

       240       250       260       270       280       290       
pF1KB0 LCEFKAHENRVKDMFSFEIPEHHVIVSASSDGFIKMWKLKQDKKVPPSLLCEINTNARLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCEFKAHENRVKDMFSFEIPEHHVIVSASSDGFIKMWKLKQDKKVPPSLLCEINTNARLT
     260       270       280       290       300       310         

       300       310       320       330       340       350       
pF1KB0 CLGVWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPGDTVHKEEKRSKPNTKKRGLTGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLGVWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPGDTVHKEEKRSKPNTKKRGLTGD
     320       330       340       350       360       370         

       360       370       380       390  
pF1KB0 SKKATKESGLISTKKRKMVEMLEKKRKKKKIKTMQ
       :::::::::::::::::::::::::::::::::::
XP_011 SKKATKESGLISTKKRKMVEMLEKKRKKKKIKTMQ
     380       390       400       410    

>>NP_060058 (OMIM: 609012) WD repeat-containing protein   (334 aa)
 initn: 148 init1: 148 opt: 264  Z-score: 224.8  bits: 50.2 E(85289): 8.8e-06
Smith-Waterman score: 267; 26.1% identity (61.8% similar) in 249 aa overlap (41-275:86-331)

               20        30        40          50        60        
pF1KB0 VLFGFAVHPEPEACGDHEQWTLVADFTHHAHTASLSAVA--VNSRFVVTGSKDETIHIYD
                                     :  ..: ::   .: ..:..: :.:..:.:
NP_060 NGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWD
          60        70        80        90       100       110     

       70        80        90        100       110       120       
pF1KB0 MKKKIEHGALVHHSGTITCLKFYGNRHLI-SGAEDGLICIWDAKKWECLKSIKAHKGQVT
       ...     .:  ::. . : .:  . .:: ::. :  . :::.:  .:::.. ::.  :.
NP_060 VSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVS
         120       130       140       150       160       170     

       130       140       150         160       170       180     
pF1KB0 FLSIHPSGKLALSVGTDKTLRTWNLVEGR--SAFIKNIKQNAHIVEWSPRGEQYVVI--I
        . .. .:.: .: . :   : :. . :.  ...: . .  . .:..:: : .:..   .
NP_060 AVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG-KYILAATL
         180       190       200       210       220        230    

           190       200       210           220        230        
pF1KB0 QNKIDIYQLDTASISGTITNEKRISSVKFLSESVLA----VAGDEE-VIRFFDCDSLVCL
       .: . ... . ..   : :..:  .   : . :: .    :.:.:. .. ... ..   .
NP_060 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIV
          240       250       260       270       280       290    

      240       250       260         270       280       290      
pF1KB0 CEFKAHENRVKDMFSFEIPEHHVIVSAS--SDGFIKMWKLKQDKKVPPSLLCEINTNARL
        ....: . :  . .   : ...:.::.  .:  ::.::                     
NP_060 QKLQGHTDVV--ISTACHPTENIIASAALENDKTIKLWKSDC                  
          300         310       320       330                      

        300       310       320       330       340       350      
pF1KB0 TCLGVWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPGDTVHKEEKRSKPNTKKRGLTG

>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta  (334 aa)
 initn: 148 init1: 148 opt: 264  Z-score: 224.8  bits: 50.2 E(85289): 8.8e-06
Smith-Waterman score: 267; 26.1% identity (61.8% similar) in 249 aa overlap (41-275:86-331)

               20        30        40          50        60        
pF1KB0 VLFGFAVHPEPEACGDHEQWTLVADFTHHAHTASLSAVA--VNSRFVVTGSKDETIHIYD
                                     :  ..: ::   .: ..:..: :.:..:.:
XP_005 NGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWD
          60        70        80        90       100       110     

       70        80        90        100       110       120       
pF1KB0 MKKKIEHGALVHHSGTITCLKFYGNRHLI-SGAEDGLICIWDAKKWECLKSIKAHKGQVT
       ...     .:  ::. . : .:  . .:: ::. :  . :::.:  .:::.. ::.  :.
XP_005 VSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVS
         120       130       140       150       160       170     

       130       140       150         160       170       180     
pF1KB0 FLSIHPSGKLALSVGTDKTLRTWNLVEGR--SAFIKNIKQNAHIVEWSPRGEQYVVI--I
        . .. .:.: .: . :   : :. . :.  ...: . .  . .:..:: : .:..   .
XP_005 AVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG-KYILAATL
         180       190       200       210       220        230    

           190       200       210           220        230        
pF1KB0 QNKIDIYQLDTASISGTITNEKRISSVKFLSESVLA----VAGDEE-VIRFFDCDSLVCL
       .: . ... . ..   : :..:  .   : . :: .    :.:.:. .. ... ..   .
XP_005 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIV
          240       250       260       270       280       290    

      240       250       260         270       280       290      
pF1KB0 CEFKAHENRVKDMFSFEIPEHHVIVSAS--SDGFIKMWKLKQDKKVPPSLLCEINTNARL
        ....: . :  . .   : ...:.::.  .:  ::.::                     
XP_005 QKLQGHTDVV--ISTACHPTENIIASAALENDKTIKLWKSDC                  
          300         310       320       330                      

        300       310       320       330       340       350      
pF1KB0 TCLGVWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPGDTVHKEEKRSKPNTKKRGLTG

>>NP_438172 (OMIM: 609012) WD repeat-containing protein   (334 aa)
 initn: 148 init1: 148 opt: 264  Z-score: 224.8  bits: 50.2 E(85289): 8.8e-06
Smith-Waterman score: 267; 26.1% identity (61.8% similar) in 249 aa overlap (41-275:86-331)

               20        30        40          50        60        
pF1KB0 VLFGFAVHPEPEACGDHEQWTLVADFTHHAHTASLSAVA--VNSRFVVTGSKDETIHIYD
                                     :  ..: ::   .: ..:..: :.:..:.:
NP_438 NGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWD
          60        70        80        90       100       110     

       70        80        90        100       110       120       
pF1KB0 MKKKIEHGALVHHSGTITCLKFYGNRHLI-SGAEDGLICIWDAKKWECLKSIKAHKGQVT
       ...     .:  ::. . : .:  . .:: ::. :  . :::.:  .:::.. ::.  :.
NP_438 VSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVS
         120       130       140       150       160       170     

       130       140       150         160       170       180     
pF1KB0 FLSIHPSGKLALSVGTDKTLRTWNLVEGR--SAFIKNIKQNAHIVEWSPRGEQYVVI--I
        . .. .:.: .: . :   : :. . :.  ...: . .  . .:..:: : .:..   .
NP_438 AVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG-KYILAATL
         180       190       200       210       220        230    

           190       200       210           220        230        
pF1KB0 QNKIDIYQLDTASISGTITNEKRISSVKFLSESVLA----VAGDEE-VIRFFDCDSLVCL
       .: . ... . ..   : :..:  .   : . :: .    :.:.:. .. ... ..   .
NP_438 DNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIV
          240       250       260       270       280       290    

      240       250       260         270       280       290      
pF1KB0 CEFKAHENRVKDMFSFEIPEHHVIVSAS--SDGFIKMWKLKQDKKVPPSLLCEINTNARL
        ....: . :  . .   : ...:.::.  .:  ::.::                     
NP_438 QKLQGHTDVV--ISTACHPTENIIASAALENDKTIKLWKSDC                  
          300         310       320       330                      

        300       310       320       330       340       350      
pF1KB0 TCLGVWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPGDTVHKEEKRSKPNTKKRGLTG

>>XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 cen  (246 aa)
 initn: 239 init1: 125 opt: 232  Z-score: 201.6  bits: 45.4 E(85289): 0.00017
Smith-Waterman score: 232; 28.8% identity (65.2% similar) in 132 aa overlap (40-168:101-230)

      10        20        30        40        50          60       
pF1KB0 QVLFGFAVHPEPEACGDHEQWTLVADFTHHAHTASLSAVAVNS--RFVVTGSKDETIHIY
                                     ::::.. .:   :  .  ::.: :.:....
XP_011 PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW
               80        90       100       110       120       130

        70        80        90        100       110       120      
pF1KB0 DMKKKIEHGALVHHSGTITCLKFYGN-RHLISGAEDGLICIWDAKKWECLKSIKAHKGQV
         ...    .: .: . . : ::  . : ..:...:  . .:: .. ::..:   : : :
XP_011 ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFV
              140       150       160       170       180       190

        130       140       150       160       170       180      
pF1KB0 TFLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPRGEQYVVIIQNK
       :....::::    ..: :.:...:..   :  .... . ..:                  
XP_011 TYVDFHPSGTCIAAAGMDNTVKVWDVRTHR--LLQHYQWTSHHCCLFKNGGVFCFWRL  
              200       210       220         230       240        

        190       200       210       220       230       240      
pF1KB0 IDIYQLDTASISGTITNEKRISSVKFLSESVLAVAGDEEVIRFFDCDSLVCLCEFKAHEN

>>XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 cen  (246 aa)
 initn: 239 init1: 125 opt: 232  Z-score: 201.6  bits: 45.4 E(85289): 0.00017
Smith-Waterman score: 232; 28.8% identity (65.2% similar) in 132 aa overlap (40-168:101-230)

      10        20        30        40        50          60       
pF1KB0 QVLFGFAVHPEPEACGDHEQWTLVADFTHHAHTASLSAVAVNS--RFVVTGSKDETIHIY
                                     ::::.. .:   :  .  ::.: :.:....
XP_011 PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW
               80        90       100       110       120       130

        70        80        90        100       110       120      
pF1KB0 DMKKKIEHGALVHHSGTITCLKFYGN-RHLISGAEDGLICIWDAKKWECLKSIKAHKGQV
         ...    .: .: . . : ::  . : ..:...:  . .:: .. ::..:   : : :
XP_011 ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFV
              140       150       160       170       180       190

        130       140       150       160       170       180      
pF1KB0 TFLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPRGEQYVVIIQNK
       :....::::    ..: :.:...:..   :  .... . ..:                  
XP_011 TYVDFHPSGTCIAAAGMDNTVKVWDVRTHR--LLQHYQWTSHHCCLFKNGGVFCFWRL  
              200       210       220         230       240        

        190       200       210       220       230       240      
pF1KB0 IDIYQLDTASISGTITNEKRISSVKFLSESVLAVAGDEEVIRFFDCDSLVCLCEFKAHEN

>>XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 cen  (246 aa)
 initn: 239 init1: 125 opt: 232  Z-score: 201.6  bits: 45.4 E(85289): 0.00017
Smith-Waterman score: 232; 28.8% identity (65.2% similar) in 132 aa overlap (40-168:101-230)

      10        20        30        40        50          60       
pF1KB0 QVLFGFAVHPEPEACGDHEQWTLVADFTHHAHTASLSAVAVNS--RFVVTGSKDETIHIY
                                     ::::.. .:   :  .  ::.: :.:....
XP_011 PSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW
               80        90       100       110       120       130

        70        80        90        100       110       120      
pF1KB0 DMKKKIEHGALVHHSGTITCLKFYGN-RHLISGAEDGLICIWDAKKWECLKSIKAHKGQV
         ...    .: .: . . : ::  . : ..:...:  . .:: .. ::..:   : : :
XP_011 ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFV
              140       150       160       170       180       190

        130       140       150       160       170       180      
pF1KB0 TFLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPRGEQYVVIIQNK
       :....::::    ..: :.:...:..   :  .... . ..:                  
XP_011 TYVDFHPSGTCIAAAGMDNTVKVWDVRTHR--LLQHYQWTSHHCCLFKNGGVFCFWRL  
              200       210       220         230       240        

        190       200       210       220       230       240      
pF1KB0 IDIYQLDTASISGTITNEKRISSVKFLSESVLAVAGDEEVIRFFDCDSLVCLCEFKAHEN




392 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 17:23:15 2016 done: Sat Nov  5 17:23:17 2016
 Total Scan time:  8.940 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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