FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0950, 407 aa 1>>>pF1KB0950 407 - 407 aa - 407 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4046+/-0.000791; mu= 8.6532+/- 0.047 mean_var=158.6809+/-31.857, 0's: 0 Z-trim(114.1): 8 B-trim: 70 in 1/51 Lambda= 0.101815 statistics sampled from 14674 (14678) to 14674 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.451), width: 16 Scan time: 3.430 The best scores are: opt bits E(32554) CCDS12567.1 EGLN2 gene_id:112398|Hs108|chr19 ( 407) 2845 429.4 2.9e-120 CCDS1595.1 EGLN1 gene_id:54583|Hs108|chr1 ( 426) 1147 180.0 3.7e-45 CCDS9646.1 EGLN3 gene_id:112399|Hs108|chr14 ( 239) 1002 158.5 6.1e-39 CCDS76671.1 EGLN3 gene_id:112399|Hs108|chr14 ( 145) 662 108.4 4.5e-24 >>CCDS12567.1 EGLN2 gene_id:112398|Hs108|chr19 (407 aa) initn: 2845 init1: 2845 opt: 2845 Z-score: 2272.5 bits: 429.4 E(32554): 2.9e-120 Smith-Waterman score: 2845; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407) 10 20 30 40 50 60 pF1KB0 MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 SGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 SGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 WAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 WAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 YIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 YIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 AWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 AWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 PHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEV 310 320 330 340 350 360 370 380 390 400 pF1KB0 KPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT ::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 KPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT 370 380 390 400 >>CCDS1595.1 EGLN1 gene_id:54583|Hs108|chr1 (426 aa) initn: 1109 init1: 1079 opt: 1147 Z-score: 924.3 bits: 180.0 E(32554): 3.7e-45 Smith-Waterman score: 1158; 50.7% identity (70.4% similar) in 371 aa overlap (35-403:60-417) 10 20 30 40 50 60 pF1KB0 CQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAGSGTP : :. : . : : .: :. : CCDS15 LLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAP---PAAVPPP 30 40 50 60 70 80 70 80 90 100 110 120 pF1KB0 RATATSTT-ASPLRDGFGGQDG-GELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWA :: : :. ::. .:. . :... :: .. :. :: :.. : . : CCDS15 RAGAREPRKAAARRDNASGDAAKGKVKAKPPADPAAAASP-CR--AAAGGQGSAVAAE-A 90 100 110 120 130 140 130 140 150 160 170 180 pF1KB0 EDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYI : : . : :.. ... . . . . : :.: : . . ::. .:::.:: CCDS15 EPGKEEP-PARSSLFQEKANLYPPSNTPGDALSPGGGLRPNG-QTKPLPAL--KLALEYI 150 160 170 180 190 190 200 210 220 230 240 pF1KB0 VPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAW :::: .:::: :.::: : .. ::.::. :.. :::::::.. ..::::.:.: CCDS15 VPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITW 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB0 VEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPH .::.::::..:: ::. .: .:::: :.:::: :::::::::::::::: :::::::::. CCDS15 IEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPN 260 270 280 290 300 310 310 320 330 340 350 360 pF1KB0 GDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKP :::::.:::::::..::.:: ::.:.:::::. :.::: :::::.:::::::::::.: CCDS15 GDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQP 320 330 340 350 360 370 370 380 390 400 pF1KB0 AYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT ::::::::::::::: ::: :: :: .:.:::.: ...: CCDS15 AYATRYAITVWYFDADERARAKVKYL--TGEKGVRVELNKPSDSVGKDVF 380 390 400 410 420 >>CCDS9646.1 EGLN3 gene_id:112399|Hs108|chr14 (239 aa) initn: 1025 init1: 820 opt: 1002 Z-score: 812.6 bits: 158.5 E(32554): 6.1e-39 Smith-Waterman score: 1002; 61.9% identity (86.0% similar) in 215 aa overlap (175-388:12-226) 150 160 170 180 190 200 pF1KB0 EREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYIVPCMRYYGICVKDSFLGAALGG :..::.:::::.. :.: :.::: ..: CCDS96 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGD 10 20 30 40 210 220 230 240 250 260 pF1KB0 RVLAEVEALKRGGRLRDGQLVSQRA-IPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAV :: .:. :. : ::::::.. :: . : .:::::.:. :.: ::..:. :.. .: . CCDS96 CVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRL 50 60 70 80 90 100 270 280 290 300 310 320 pF1KB0 IRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVH . .:..:::.: .. :.::::::::::: :::::::::.:::::::::::::.:::.:.: CCDS96 VLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLH 110 120 130 140 150 160 330 340 350 360 370 380 pF1KB0 GGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAA ::.:.:::::. .:..::.:::::.:::::::::::.:.::::::.:::::::.::: : CCDS96 GGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEA 170 180 190 200 210 220 390 400 pF1KB0 KDKYQLASGQKGVQVPVSQPPTPT : :.. CCDS96 KKKFRNLTRKTESALTED 230 >>CCDS76671.1 EGLN3 gene_id:112399|Hs108|chr14 (145 aa) initn: 716 init1: 655 opt: 662 Z-score: 545.6 bits: 108.4 E(32554): 4.5e-24 Smith-Waterman score: 662; 73.9% identity (92.2% similar) in 115 aa overlap (274-388:18-132) 250 260 270 280 290 300 pF1KB0 EGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHG :.. .:::::::::: :::::::::.: CCDS76 MPLGHIMRLDLEKIALEYIVPCLHEAMVACYPGNGTGYVRHVDNPNG 10 20 30 40 310 320 330 340 350 360 pF1KB0 DGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPA ::::::::::::.:::.:.:::.:.:::::. .:..::.:::::.:::::::::::.:. CCDS76 DGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPS 50 60 70 80 90 100 370 380 390 400 pF1KB0 YATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT ::::::.:::::::.::: :: :.. CCDS76 YATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED 110 120 130 140 407 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:25:39 2016 done: Sat Nov 5 17:25:39 2016 Total Scan time: 3.430 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]