Result of FASTA (omim) for
pF1KB0950
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0950, 407 aa
1>>>pF1KB0950 407 - 407 aa - 407 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9597+/-0.000335; mu= 5.3458+/- 0.021
mean_var=171.6882+/-35.123, 0's: 0 Z-trim(121.2): 7 B-trim: 311 in 1/56
Lambda= 0.097882
statistics sampled from 37492 (37499) to 37492 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.44), width: 16
Scan time: 9.950
The best scores are: opt bits E(85289)
NP_444274 (OMIM: 606424) egl nine homolog 2 [Homo ( 407) 2845 413.6 4.4e-115
NP_542770 (OMIM: 606424) egl nine homolog 2 [Homo ( 407) 2845 413.6 4.4e-115
NP_071334 (OMIM: 606425,609070,609820) egl nine ho ( 426) 1147 173.8 6.9e-43
NP_071356 (OMIM: 606426) egl nine homolog 3 isofor ( 239) 1002 153.2 6.4e-37
XP_005273223 (OMIM: 606425,609070,609820) PREDICTE ( 383) 1005 153.7 6.9e-37
XP_005273224 (OMIM: 606425,609070,609820) PREDICTE ( 345) 762 119.4 1.4e-26
NP_001295032 (OMIM: 606426) egl nine homolog 3 iso ( 145) 662 105.0 1.2e-22
>>NP_444274 (OMIM: 606424) egl nine homolog 2 [Homo sapi (407 aa)
initn: 2845 init1: 2845 opt: 2845 Z-score: 2187.1 bits: 413.6 E(85289): 4.4e-115
Smith-Waterman score: 2845; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)
10 20 30 40 50 60
pF1KB0 MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 SGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 SGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 WAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 WAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 YIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 YIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 AWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 AWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 PHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 PHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEV
310 320 330 340 350 360
370 380 390 400
pF1KB0 KPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT
:::::::::::::::::::::::::::::::::::::::::::::::
NP_444 KPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT
370 380 390 400
>>NP_542770 (OMIM: 606424) egl nine homolog 2 [Homo sapi (407 aa)
initn: 2845 init1: 2845 opt: 2845 Z-score: 2187.1 bits: 413.6 E(85289): 4.4e-115
Smith-Waterman score: 2845; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)
10 20 30 40 50 60
pF1KB0 MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 SGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 WAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 WAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 YIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 YIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 AWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 AWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 PHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEV
310 320 330 340 350 360
370 380 390 400
pF1KB0 KPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT
:::::::::::::::::::::::::::::::::::::::::::::::
NP_542 KPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT
370 380 390 400
>>NP_071334 (OMIM: 606425,609070,609820) egl nine homolo (426 aa)
initn: 1109 init1: 1079 opt: 1147 Z-score: 890.9 bits: 173.8 E(85289): 6.9e-43
Smith-Waterman score: 1158; 50.7% identity (70.4% similar) in 371 aa overlap (35-403:60-417)
10 20 30 40 50 60
pF1KB0 CQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAGSGTP
: :. : . : : .: :. :
NP_071 LLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAP---PAAVPPP
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB0 RATATSTT-ASPLRDGFGGQDG-GELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWA
:: : :. ::. .:. . :... :: .. :. :: :.. : . :
NP_071 RAGAREPRKAAARRDNASGDAAKGKVKAKPPADPAAAASP-CR--AAAGGQGSAVAAE-A
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB0 EDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYI
: : . : :.. ... . . . . : :.: : . . ::. .:::.::
NP_071 EPGKEEP-PARSSLFQEKANLYPPSNTPGDALSPGGGLRPNG-QTKPLPAL--KLALEYI
150 160 170 180 190
190 200 210 220 230 240
pF1KB0 VPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAW
:::: .:::: :.::: : .. ::.::. :.. :::::::.. ..::::.:.:
NP_071 VPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITW
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB0 VEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPH
.::.::::..:: ::. .: .:::: :.:::: :::::::::::::::: :::::::::.
NP_071 IEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPN
260 270 280 290 300 310
310 320 330 340 350 360
pF1KB0 GDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKP
:::::.:::::::..::.:: ::.:.:::::. :.::: :::::.:::::::::::.:
NP_071 GDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQP
320 330 340 350 360 370
370 380 390 400
pF1KB0 AYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT
::::::::::::::: ::: :: :: .:.:::.: ...:
NP_071 AYATRYAITVWYFDADERARAKVKYL--TGEKGVRVELNKPSDSVGKDVF
380 390 400 410 420
>>NP_071356 (OMIM: 606426) egl nine homolog 3 isoform 1 (239 aa)
initn: 1025 init1: 820 opt: 1002 Z-score: 783.8 bits: 153.2 E(85289): 6.4e-37
Smith-Waterman score: 1002; 61.9% identity (86.0% similar) in 215 aa overlap (175-388:12-226)
150 160 170 180 190 200
pF1KB0 EREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYIVPCMRYYGICVKDSFLGAALGG
:..::.:::::.. :.: :.::: ..:
NP_071 MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGD
10 20 30 40
210 220 230 240 250 260
pF1KB0 RVLAEVEALKRGGRLRDGQLVSQRA-IPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAV
:: .:. :. : ::::::.. :: . : .:::::.:. :.: ::..:. :.. .: .
NP_071 CVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRL
50 60 70 80 90 100
270 280 290 300 310 320
pF1KB0 IRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVH
. .:..:::.: .. :.::::::::::: :::::::::.:::::::::::::.:::.:.:
NP_071 VLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLH
110 120 130 140 150 160
330 340 350 360 370 380
pF1KB0 GGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAA
::.:.:::::. .:..::.:::::.:::::::::::.:.::::::.:::::::.::: :
NP_071 GGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEA
170 180 190 200 210 220
390 400
pF1KB0 KDKYQLASGQKGVQVPVSQPPTPT
: :..
NP_071 KKKFRNLTRKTESALTED
230
>>XP_005273223 (OMIM: 606425,609070,609820) PREDICTED: e (383 aa)
initn: 1022 init1: 971 opt: 1005 Z-score: 783.2 bits: 153.7 E(85289): 6.9e-37
Smith-Waterman score: 1016; 49.3% identity (69.0% similar) in 335 aa overlap (35-367:60-383)
10 20 30 40 50 60
pF1KB0 CQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAGSGTP
: :. : . : : .: : :
XP_005 LLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVP---PP
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB0 RATATSTT-ASPLRDGFGGQDG-GELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWA
:: : :. ::. .:. . :... :: .. :. :: :.. : . :
XP_005 RAGAREPRKAAARRDNASGDAAKGKVKAKPPADPAAAASP-CR--AAAGGQGSAVAAE-A
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB0 EDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYI
: : . : :.. ... . . . . : :.: : . . ::. .:::.::
XP_005 EPGKEEP-PARSSLFQEKANLYPPSNTPGDALSPGGGLRPNG-QTKPLPAL--KLALEYI
150 160 170 180 190
190 200 210 220 230 240
pF1KB0 VPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAW
:::: .:::: :.::: : .. ::.::. :.. :::::::.. ..::::.:.:
XP_005 VPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITW
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB0 VEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPH
.::.::::..:: ::. .: .:::: :.:::: :::::::::::::::: :::::::::.
XP_005 IEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPN
260 270 280 290 300 310
310 320 330 340 350 360
pF1KB0 GDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKP
:::::.:::::::..::.:: ::.:.:::::. :.::: :::::.:::::::::::.:
XP_005 GDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQP
320 330 340 350 360 370
370 380 390 400
pF1KB0 AYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT
:::::
XP_005 AYATR
380
>>XP_005273224 (OMIM: 606425,609070,609820) PREDICTED: e (345 aa)
initn: 776 init1: 725 opt: 762 Z-score: 598.4 bits: 119.4 E(85289): 1.4e-26
Smith-Waterman score: 773; 44.7% identity (66.4% similar) in 295 aa overlap (35-327:60-343)
10 20 30 40 50 60
pF1KB0 CQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAGSGTP
: :. : . : : .: :. :
XP_005 LLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPP---AAVPPP
30 40 50 60 70 80
70 80 90 100 110 120
pF1KB0 RATATSTT-ASPLRDGFGGQDG-GELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWA
:: : :. ::. .:. . :... :: .. :. :: :.. : . :
XP_005 RAGAREPRKAAARRDNASGDAAKGKVKAKPPADPAAAASP-CR--AAAGGQGSAVAAE-A
90 100 110 120 130 140
130 140 150 160 170 180
pF1KB0 EDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYI
: : . : :.. ... . . . . : :.: : . . ::. .:::.::
XP_005 EPGKEEP-PARSSLFQEKANLYPPSNTPGDALSPGGGLRPNG-QTKPLPAL--KLALEYI
150 160 170 180 190
190 200 210 220 230 240
pF1KB0 VPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAW
:::: .:::: :.::: : .. ::.::. :.. :::::::.. ..::::.:.:
XP_005 VPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITW
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB0 VEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPH
.::.::::..:: ::. .: .:::: :.:::: :::::::::::::::: :::::::::.
XP_005 IEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPN
260 270 280 290 300 310
310 320 330 340 350 360
pF1KB0 GDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKP
:::::.:::::::..::.::... :
XP_005 GDGRCVTCIYYLNKDWDAKVRNNCLVF
320 330 340
>>NP_001295032 (OMIM: 606426) egl nine homolog 3 isoform (145 aa)
initn: 716 init1: 655 opt: 662 Z-score: 527.3 bits: 105.0 E(85289): 1.2e-22
Smith-Waterman score: 662; 73.9% identity (92.2% similar) in 115 aa overlap (274-388:18-132)
250 260 270 280 290 300
pF1KB0 EGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHG
:.. .:::::::::: :::::::::.:
NP_001 MPLGHIMRLDLEKIALEYIVPCLHEAMVACYPGNGTGYVRHVDNPNG
10 20 30 40
310 320 330 340 350 360
pF1KB0 DGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPA
::::::::::::.:::.:.:::.:.:::::. .:..::.:::::.:::::::::::.:.
NP_001 DGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPS
50 60 70 80 90 100
370 380 390 400
pF1KB0 YATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT
::::::.:::::::.::: :: :..
NP_001 YATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED
110 120 130 140
407 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:25:40 2016 done: Sat Nov 5 17:25:41 2016
Total Scan time: 9.950 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]