FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0953, 184 aa 1>>>pF1KB0953 184 - 184 aa - 184 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1172+/-0.000405; mu= 13.9411+/- 0.026 mean_var=77.4901+/-16.591, 0's: 0 Z-trim(114.2): 226 B-trim: 2123 in 3/47 Lambda= 0.145697 statistics sampled from 23548 (23938) to 23548 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.281), width: 16 Scan time: 5.830 The best scores are: opt bits E(85289) NP_001658 (OMIM: 601175) ADP-ribosylation factor-l ( 184) 1218 265.2 4.3e-71 NP_001186674 (OMIM: 601175) ADP-ribosylation facto ( 157) 748 166.3 2.1e-41 NP_004302 (OMIM: 604695) ADP-ribosylation factor-l ( 182) 663 148.5 5.5e-36 XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosyl ( 182) 663 148.5 5.5e-36 XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 181) 561 127.1 1.6e-29 NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 ( 181) 561 127.1 1.6e-29 NP_001019397 (OMIM: 103180) ADP-ribosylation facto ( 181) 553 125.4 5e-29 NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 ( 181) 553 125.4 5e-29 NP_001019399 (OMIM: 103180) ADP-ribosylation facto ( 181) 553 125.4 5e-29 NP_001019398 (OMIM: 103180) ADP-ribosylation facto ( 181) 553 125.4 5e-29 NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 ( 180) 547 124.1 1.2e-28 NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 ( 180) 547 124.1 1.2e-28 NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 ( 175) 528 120.1 1.9e-27 NP_001168 (OMIM: 603425) ADP-ribosylation factor-l ( 181) 498 113.8 1.5e-25 XP_005248554 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 398) 495 113.5 4.2e-25 NP_001647 (OMIM: 601747) E3 ubiquitin-protein liga ( 574) 495 113.6 5.6e-25 NP_848930 (OMIM: 608909) ADP-ribosylation factor-l ( 179) 489 111.9 5.6e-25 NP_036229 (OMIM: 608960) ADP-ribosylation factor-l ( 179) 484 110.9 1.2e-24 NP_079323 (OMIM: 614439) ADP-ribosylation factor-l ( 192) 476 109.2 3.9e-24 XP_005266310 (OMIM: 609351) PREDICTED: ADP-ribosyl ( 196) 452 104.2 1.3e-22 NP_612459 (OMIM: 609351) ADP-ribosylation factor-l ( 196) 452 104.2 1.3e-22 XP_016864933 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 569) 449 104.0 4.5e-22 NP_150230 (OMIM: 601747) E3 ubiquitin-protein liga ( 569) 449 104.0 4.5e-22 XP_006719454 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 137) 421 97.6 9.2e-21 XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosyl ( 212) 417 96.9 2.3e-20 NP_150231 (OMIM: 601747) E3 ubiquitin-protein liga ( 546) 418 97.4 4e-20 XP_005252458 (OMIM: 608909) PREDICTED: ADP-ribosyl ( 142) 409 95.0 5.4e-20 NP_878899 (OMIM: 608922,612291) ADP-ribosylation f ( 428) 414 96.5 6e-20 NP_001167621 (OMIM: 608922,612291) ADP-ribosylatio ( 428) 414 96.5 6e-20 NP_115522 (OMIM: 209900,268000,600151,608845,61357 ( 186) 404 94.1 1.4e-19 NP_001265222 (OMIM: 209900,268000,600151,608845,61 ( 186) 404 94.1 1.4e-19 NP_816931 (OMIM: 209900,268000,600151,608845,61357 ( 186) 404 94.1 1.4e-19 XP_016862800 (OMIM: 209900,268000,600151,608845,61 ( 186) 404 94.1 1.4e-19 NP_001032251 (OMIM: 608960) ADP-ribosylation facto ( 142) 398 92.7 2.7e-19 NP_817114 (OMIM: 608960) ADP-ribosylation factor-l ( 142) 398 92.7 2.7e-19 NP_001310442 (OMIM: 209900,268000,600151,608845,61 ( 193) 391 91.4 9.4e-19 NP_001652 (OMIM: 600732) ADP-ribosylation factor-l ( 201) 391 91.4 9.7e-19 XP_011523084 (OMIM: 600732) PREDICTED: ADP-ribosyl ( 201) 391 91.4 9.7e-19 NP_005728 (OMIM: 604787) ADP-ribosylation factor-l ( 192) 387 90.5 1.7e-18 NP_001287997 (OMIM: 603425) ADP-ribosylation facto ( 135) 385 90.0 1.7e-18 NP_001269360 (OMIM: 604787) ADP-ribosylation facto ( 201) 387 90.6 1.7e-18 XP_011510837 (OMIM: 608922,612291) PREDICTED: ADP- ( 403) 386 90.6 3.4e-18 XP_011526785 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 381 89.3 4.2e-18 XP_016883065 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 381 89.3 4.2e-18 NP_001254477 (OMIM: 604699) ADP-ribosylation facto ( 201) 381 89.3 4.2e-18 XP_011526784 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 381 89.3 4.2e-18 NP_003215 (OMIM: 604699) ADP-ribosylation factor-r ( 201) 381 89.3 4.2e-18 NP_001254476 (OMIM: 604699) ADP-ribosylation facto ( 201) 381 89.3 4.2e-18 NP_620150 (OMIM: 616597) ADP-ribosylation factor-l ( 186) 367 86.3 3e-17 NP_060654 (OMIM: 616596) ADP-ribosylation factor-l ( 186) 365 85.9 4e-17 >>NP_001658 (OMIM: 601175) ADP-ribosylation factor-like (184 aa) initn: 1218 init1: 1218 opt: 1218 Z-score: 1397.4 bits: 265.2 E(85289): 4.3e-71 Smith-Waterman score: 1218; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB0 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGATL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 LIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRI 130 140 150 160 170 180 pF1KB0 FTAD :::: NP_001 FTAD >>NP_001186674 (OMIM: 601175) ADP-ribosylation factor-li (157 aa) initn: 766 init1: 748 opt: 748 Z-score: 864.4 bits: 166.3 E(85289): 2.1e-41 Smith-Waterman score: 990; 85.3% identity (85.3% similar) in 184 aa overlap (1-184:1-157) 10 20 30 40 50 60 pF1KB0 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 KLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGATL ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEE------- 70 80 90 100 110 130 140 150 160 170 180 pF1KB0 LIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRI :::::::::::::::::::::::::::::::::::::::: NP_001 --------------------VLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRI 120 130 140 150 pF1KB0 FTAD :::: NP_001 FTAD >>NP_004302 (OMIM: 604695) ADP-ribosylation factor-like (182 aa) initn: 635 init1: 594 opt: 663 Z-score: 767.0 bits: 148.5 E(85289): 5.5e-36 Smith-Waterman score: 663; 53.3% identity (83.9% similar) in 180 aa overlap (1-179:1-180) 10 20 30 40 50 pF1KB0 MGLLTILKKMKQK-ERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRG ::::.::.:.:. ..:.:.:.::::::::::.::.. .:::. :.:: :::::... .: NP_004 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 FKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGAT ::::.::.:::...: ::.::::.:: ::.:.:::::.:... .:: :: ::.:. . NP_004 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 LLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSR .::::::::: : .. : : :.: .::.. : ::.:::.:::.. :..:. ..... NP_004 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK 130 140 150 160 170 180 180 pF1KB0 IFTAD NP_004 KK >>XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosylatio (182 aa) initn: 635 init1: 594 opt: 663 Z-score: 767.0 bits: 148.5 E(85289): 5.5e-36 Smith-Waterman score: 663; 53.3% identity (83.9% similar) in 180 aa overlap (1-179:1-180) 10 20 30 40 50 pF1KB0 MGLLTILKKMKQK-ERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRG ::::.::.:.:. ..:.:.:.::::::::::.::.. .:::. :.:: :::::... .: XP_016 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 FKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGAT ::::.::.:::...: ::.::::.:: ::.:.:::::.:... .:: :: ::.:. . XP_016 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 LLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSR .::::::::: : .. : : :.: .::.. : ::.:::.:::.. :..:. ..... XP_016 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK 130 140 150 160 170 180 180 pF1KB0 IFTAD XP_016 KK >>XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosylatio (181 aa) initn: 533 init1: 533 opt: 561 Z-score: 651.1 bits: 127.1 E(85289): 1.6e-29 Smith-Waterman score: 561; 47.4% identity (82.9% similar) in 175 aa overlap (6-179:8-180) 10 20 30 40 50 pF1KB0 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFN-GEDIDTISPTLGFNIKTLEH .::.. : .:.:.::.::: ::::::: :.. :: . :: ::.:::..:.:. XP_005 MGNIFGNLLKSLIGK-KEMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVETVEY 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 RGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAG .......:::::: ..: ::.::..:.:::.:::: ::.:... ..::. .:.:..: XP_005 KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 ATLLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDIS :.::.::::::::.:... : . : : :.: ..: ::. :..:..: :.::: .... XP_005 AVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLK 120 130 140 150 160 170 180 pF1KB0 SRIFTAD .. XP_005 NKK 180 >>NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 [Ho (181 aa) initn: 533 init1: 533 opt: 561 Z-score: 651.1 bits: 127.1 E(85289): 1.6e-29 Smith-Waterman score: 561; 47.4% identity (82.9% similar) in 175 aa overlap (6-179:8-180) 10 20 30 40 50 pF1KB0 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFN-GEDIDTISPTLGFNIKTLEH .::.. : .:.:.::.::: ::::::: :.. :: . :: ::.:::..:.:. NP_001 MGNIFGNLLKSLIGK-KEMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVETVEY 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 RGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAG .......:::::: ..: ::.::..:.:::.:::: ::.:... ..::. .:.:..: NP_001 KNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 ATLLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDIS :.::.::::::::.:... : . : : :.: ..: ::. :..:..: :.::: .... NP_001 AVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLK 120 130 140 150 160 170 180 pF1KB0 SRIFTAD .. NP_001 NKK 180 >>NP_001019397 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 529 init1: 529 opt: 553 Z-score: 642.1 bits: 125.4 E(85289): 5e-29 Smith-Waterman score: 553; 47.9% identity (83.2% similar) in 167 aa overlap (14-179:15-180) 10 20 30 40 50 pF1KB0 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFN-GEDIDTISPTLGFNIKTLEHR ..:.:.::.::: ::::::: :.. :: . :: ::.:::..:.:.. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVETVEYK 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 GFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGA ......:::::: ..: ::.::..:.:::.:::: ::.:... ..::. .:.:..: : NP_001 NISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 TLLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISS .::.::::::::.:... : . : : :.: ..: ::. :..:..: :.::: ... . NP_001 VLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRN 120 130 140 150 160 170 180 pF1KB0 RIFTAD . NP_001 QK 180 >>NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 [Ho (181 aa) initn: 529 init1: 529 opt: 553 Z-score: 642.1 bits: 125.4 E(85289): 5e-29 Smith-Waterman score: 553; 47.9% identity (83.2% similar) in 167 aa overlap (14-179:15-180) 10 20 30 40 50 pF1KB0 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFN-GEDIDTISPTLGFNIKTLEHR ..:.:.::.::: ::::::: :.. :: . :: ::.:::..:.:.. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVETVEYK 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 GFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGA ......:::::: ..: ::.::..:.:::.:::: ::.:... ..::. .:.:..: : NP_001 NISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 TLLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISS .::.::::::::.:... : . : : :.: ..: ::. :..:..: :.::: ... . NP_001 VLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRN 120 130 140 150 160 170 180 pF1KB0 RIFTAD . NP_001 QK 180 >>NP_001019399 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 529 init1: 529 opt: 553 Z-score: 642.1 bits: 125.4 E(85289): 5e-29 Smith-Waterman score: 553; 47.9% identity (83.2% similar) in 167 aa overlap (14-179:15-180) 10 20 30 40 50 pF1KB0 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFN-GEDIDTISPTLGFNIKTLEHR ..:.:.::.::: ::::::: :.. :: . :: ::.:::..:.:.. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVETVEYK 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 GFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGA ......:::::: ..: ::.::..:.:::.:::: ::.:... ..::. .:.:..: : NP_001 NISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 TLLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISS .::.::::::::.:... : . : : :.: ..: ::. :..:..: :.::: ... . NP_001 VLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRN 120 130 140 150 160 170 180 pF1KB0 RIFTAD . NP_001 QK 180 >>NP_001019398 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 529 init1: 529 opt: 553 Z-score: 642.1 bits: 125.4 E(85289): 5e-29 Smith-Waterman score: 553; 47.9% identity (83.2% similar) in 167 aa overlap (14-179:15-180) 10 20 30 40 50 pF1KB0 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFN-GEDIDTISPTLGFNIKTLEHR ..:.:.::.::: ::::::: :.. :: . :: ::.:::..:.:.. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTI-PTIGFNVETVEYK 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 GFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGA ......:::::: ..: ::.::..:.:::.:::: ::.:... ..::. .:.:..: : NP_001 NISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 TLLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISS .::.::::::::.:... : . : : :.: ..: ::. :..:..: :.::: ... . NP_001 VLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRN 120 130 140 150 160 170 180 pF1KB0 RIFTAD . NP_001 QK 180 184 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:27:19 2016 done: Sat Nov 5 17:27:20 2016 Total Scan time: 5.830 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]