FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0962, 425 aa 1>>>pF1KB0962 425 - 425 aa - 425 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7184+/-0.000424; mu= 13.8143+/- 0.026 mean_var=207.3205+/-43.067, 0's: 0 Z-trim(118.3): 196 B-trim: 1599 in 1/55 Lambda= 0.089074 statistics sampled from 30783 (31113) to 30783 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.365), width: 16 Scan time: 8.140 The best scores are: opt bits E(85289) NP_008959 (OMIM: 609316) E3 ubiquitin-protein liga ( 425) 2852 379.3 1.1e-104 XP_011512566 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 424) 2833 376.8 5.7e-104 XP_011512567 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 421) 2731 363.7 5e-100 XP_011512568 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 261) 1728 234.5 2.4e-61 NP_003440 (OMIM: 600830) tripartite motif-containi ( 539) 637 94.7 5.9e-19 XP_006715243 (OMIM: 600830) PREDICTED: tripartite ( 539) 637 94.7 5.9e-19 XP_005249432 (OMIM: 600830) PREDICTED: tripartite ( 539) 637 94.7 5.9e-19 XP_005249431 (OMIM: 600830) PREDICTED: tripartite ( 539) 637 94.7 5.9e-19 XP_005249435 (OMIM: 600830) PREDICTED: tripartite ( 539) 637 94.7 5.9e-19 XP_005249434 (OMIM: 600830) PREDICTED: tripartite ( 539) 637 94.7 5.9e-19 NP_001229712 (OMIM: 600830) tripartite motif-conta ( 539) 637 94.7 5.9e-19 XP_005249433 (OMIM: 600830) PREDICTED: tripartite ( 539) 637 94.7 5.9e-19 NP_439893 (OMIM: 605701) tripartite motif-containi ( 395) 600 89.8 1.3e-17 NP_006769 (OMIM: 605701) tripartite motif-containi ( 481) 600 89.9 1.5e-17 NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488) 577 87.0 1.2e-16 NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 574 86.6 1.6e-16 NP_149083 (OMIM: 608487) tripartite motif-containi ( 347) 558 84.3 5.1e-16 NP_477514 (OMIM: 607564) tripartite motif-containi ( 488) 560 84.8 5.3e-16 NP_001003818 (OMIM: 607564) tripartite motif-conta ( 516) 560 84.8 5.5e-16 XP_016873951 (OMIM: 608487) PREDICTED: tripartite ( 300) 555 83.9 6.2e-16 NP_149084 (OMIM: 608487) tripartite motif-containi ( 326) 555 83.9 6.5e-16 XP_005253241 (OMIM: 608487) PREDICTED: tripartite ( 326) 555 83.9 6.5e-16 NP_149023 (OMIM: 608487) tripartite motif-containi ( 493) 555 84.2 8.3e-16 XP_005253240 (OMIM: 608487) PREDICTED: tripartite ( 493) 555 84.2 8.3e-16 XP_011518728 (OMIM: 608487) PREDICTED: tripartite ( 310) 536 81.4 3.4e-15 XP_016873950 (OMIM: 608487) PREDICTED: tripartite ( 310) 536 81.4 3.4e-15 XP_016873952 (OMIM: 608487) PREDICTED: tripartite ( 265) 532 80.8 4.4e-15 XP_006718421 (OMIM: 608487) PREDICTED: tripartite ( 265) 532 80.8 4.4e-15 XP_011518729 (OMIM: 608487) PREDICTED: tripartite ( 271) 529 80.5 5.9e-15 XP_011512527 (OMIM: 605701) PREDICTED: tripartite ( 413) 531 81.0 6.3e-15 XP_011512524 (OMIM: 605701) PREDICTED: tripartite ( 499) 531 81.1 7.1e-15 XP_011512525 (OMIM: 605701) PREDICTED: tripartite ( 499) 531 81.1 7.1e-15 XP_011512523 (OMIM: 605701) PREDICTED: tripartite ( 499) 531 81.1 7.1e-15 NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518) 526 80.5 1.1e-14 NP_660215 (OMIM: 607868) E3 ubiquitin-protein liga ( 468) 525 80.3 1.2e-14 XP_016873949 (OMIM: 608487) PREDICTED: tripartite ( 314) 520 79.4 1.4e-14 NP_003132 (OMIM: 109092) E3 ubiquitin-protein liga ( 475) 514 78.9 3.1e-14 XP_016857901 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 467) 501 77.2 9.8e-14 NP_006065 (OMIM: 606559) E3 ubiquitin-protein liga ( 498) 493 76.2 2.1e-13 NP_067629 (OMIM: 605684) tripartite motif-containi ( 488) 487 75.4 3.5e-13 NP_001003827 (OMIM: 605684) tripartite motif-conta ( 488) 487 75.4 3.5e-13 NP_001128327 (OMIM: 606123) E3 ubiquitin-protein l ( 343) 475 73.7 8.3e-13 NP_569074 (OMIM: 605684) tripartite motif-containi ( 270) 472 73.1 9.4e-13 XP_011513161 (OMIM: 600830) PREDICTED: tripartite ( 462) 474 73.7 1.1e-12 XP_016866752 (OMIM: 600830) PREDICTED: tripartite ( 462) 474 73.7 1.1e-12 NP_001186502 (OMIM: 606559) E3 ubiquitin-protein l ( 494) 472 73.5 1.3e-12 XP_011542512 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 471 73.3 1.4e-12 NP_057186 (OMIM: 606123) E3 ubiquitin-protein liga ( 477) 471 73.3 1.4e-12 NP_001020111 (OMIM: 606123) E3 ubiquitin-protein l ( 477) 471 73.3 1.4e-12 XP_011542511 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 471 73.3 1.4e-12 >>NP_008959 (OMIM: 609316) E3 ubiquitin-protein ligase T (425 aa) initn: 2852 init1: 2852 opt: 2852 Z-score: 2000.8 bits: 379.3 E(85289): 1.1e-104 Smith-Waterman score: 2852; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB0 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 RKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVCRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVCRES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 KDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEHEKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 KDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEHEKQR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVDSLKTKQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 ILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVDSLKTKQN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 MPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKKFKDQLQAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKKFKDQLQAD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNHHSSAPSHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 RKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNHHSSAPSHS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LFRASSAGKVTFPVCLLASYDEISGQGASSQDTKTFDVALSEELHAALSEWLTAIRAWFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 LFRASSAGKVTFPVCLLASYDEISGQGASSQDTKTFDVALSEELHAALSEWLTAIRAWFC 370 380 390 400 410 420 pF1KB0 EVPSS ::::: NP_008 EVPSS >>XP_011512566 (OMIM: 609316) PREDICTED: E3 ubiquitin-pr (424 aa) initn: 1728 init1: 1728 opt: 2833 Z-score: 1987.6 bits: 376.8 E(85289): 5.7e-104 Smith-Waterman score: 2833; 99.8% identity (99.8% similar) in 425 aa overlap (1-425:1-424) 10 20 30 40 50 60 pF1KB0 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 RKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVCRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVCRES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 KDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEHEKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEHEKQR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVDSLKTKQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVDSLKTKQN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 MPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKKFKDQLQAD ::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::: XP_011 MPPRQLLEDIKVVLC-SEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKKFKDQLQAD 250 260 270 280 290 310 320 330 340 350 360 pF1KB0 RKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNHHSSAPSHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNHHSSAPSHS 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB0 LFRASSAGKVTFPVCLLASYDEISGQGASSQDTKTFDVALSEELHAALSEWLTAIRAWFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFRASSAGKVTFPVCLLASYDEISGQGASSQDTKTFDVALSEELHAALSEWLTAIRAWFC 360 370 380 390 400 410 pF1KB0 EVPSS ::::: XP_011 EVPSS 420 >>XP_011512567 (OMIM: 609316) PREDICTED: E3 ubiquitin-pr (421 aa) initn: 2731 init1: 2731 opt: 2731 Z-score: 1916.8 bits: 363.7 E(85289): 5e-100 Smith-Waterman score: 2731; 99.8% identity (99.8% similar) in 410 aa overlap (1-410:1-410) 10 20 30 40 50 60 pF1KB0 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 RKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVCRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVCRES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 KDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEHEKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEHEKQR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVDSLKTKQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVDSLKTKQN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 MPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKKFKDQLQAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKKFKDQLQAD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNHHSSAPSHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNHHSSAPSHS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LFRASSAGKVTFPVCLLASYDEISGQGASSQDTKTFDVALSEELHAALSEWLTAIRAWFC :::::::::::::::::::::::::::::::::::::::::::::::: : XP_011 LFRASSAGKVTFPVCLLASYDEISGQGASSQDTKTFDVALSEELHAALMEKGSPCSSPRT 370 380 390 400 410 420 pF1KB0 EVPSS XP_011 L >>XP_011512568 (OMIM: 609316) PREDICTED: E3 ubiquitin-pr (261 aa) initn: 1728 init1: 1728 opt: 1728 Z-score: 1222.4 bits: 234.5 E(85289): 2.4e-61 Smith-Waterman score: 1728; 99.6% identity (99.6% similar) in 257 aa overlap (1-257:1-257) 10 20 30 40 50 60 pF1KB0 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 RKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVCRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVCRES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 KDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEHEKQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEHEKQR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 ILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVDSLKTKQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVDSLKTKQN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 MPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKKFKDQLQAD ::::::::::::::: : XP_011 MPPRQLLEDIKVVLCSSTTSS 250 260 >>NP_003440 (OMIM: 600830) tripartite motif-containing p (539 aa) initn: 596 init1: 360 opt: 637 Z-score: 461.3 bits: 94.7 E(85289): 5.9e-19 Smith-Waterman score: 637; 34.7% identity (65.6% similar) in 308 aa overlap (1-300:1-307) 10 20 30 40 50 60 pF1KB0 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV ::.. . .:.::: : :::: :. :::::::: :: .: :.. : . ::::: NP_003 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 RKNAIRFNSLLRNLVEKIQAL------QASEVQSKRKEAT-CPRHQEMFHYFCEDDGKFL .:. :: : .:::.:. : : .:: ....: : ::.: .::.::::::.: NP_003 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 CFVCRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQ-VKAQGVHRVDVFTD : .::::..:. :.. :.:.::: .. .: .....:. .... .: .:.: . . NP_003 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLR-RDRDKIQGFQAKGEADILAALK 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 QVEHEKQRILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLV ... ..: :..::: :: :.:... :: .. : .: ::. ... . .: : .. NP_003 KLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 DSLKTKQNMPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKK . :. : ..: .:..: . : : . .: :. ..:: .: ... :. .:.. NP_003 SELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLRE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 FKDQLQADRKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNH :. .: : NP_003 FQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLG 300 310 320 330 340 350 >>XP_006715243 (OMIM: 600830) PREDICTED: tripartite moti (539 aa) initn: 596 init1: 360 opt: 637 Z-score: 461.3 bits: 94.7 E(85289): 5.9e-19 Smith-Waterman score: 637; 34.7% identity (65.6% similar) in 308 aa overlap (1-300:1-307) 10 20 30 40 50 60 pF1KB0 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV ::.. . .:.::: : :::: :. :::::::: :: .: :.. : . ::::: XP_006 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 RKNAIRFNSLLRNLVEKIQAL------QASEVQSKRKEAT-CPRHQEMFHYFCEDDGKFL .:. :: : .:::.:. : : .:: ....: : ::.: .::.::::::.: XP_006 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 CFVCRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQ-VKAQGVHRVDVFTD : .::::..:. :.. :.:.::: .. .: .....:. .... .: .:.: . . XP_006 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLR-RDRDKIQGFQAKGEADILAALK 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 QVEHEKQRILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLV ... ..: :..::: :: :.:... :: .. : .: ::. ... . .: : .. XP_006 KLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 DSLKTKQNMPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKK . :. : ..: .:..: . : : . .: :. ..:: .: ... :. .:.. XP_006 SELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLRE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 FKDQLQADRKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNH :. .: : XP_006 FQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLG 300 310 320 330 340 350 >>XP_005249432 (OMIM: 600830) PREDICTED: tripartite moti (539 aa) initn: 596 init1: 360 opt: 637 Z-score: 461.3 bits: 94.7 E(85289): 5.9e-19 Smith-Waterman score: 637; 34.7% identity (65.6% similar) in 308 aa overlap (1-300:1-307) 10 20 30 40 50 60 pF1KB0 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV ::.. . .:.::: : :::: :. :::::::: :: .: :.. : . ::::: XP_005 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 RKNAIRFNSLLRNLVEKIQAL------QASEVQSKRKEAT-CPRHQEMFHYFCEDDGKFL .:. :: : .:::.:. : : .:: ....: : ::.: .::.::::::.: XP_005 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 CFVCRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQ-VKAQGVHRVDVFTD : .::::..:. :.. :.:.::: .. .: .....:. .... .: .:.: . . XP_005 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLR-RDRDKIQGFQAKGEADILAALK 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 QVEHEKQRILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLV ... ..: :..::: :: :.:... :: .. : .: ::. ... . .: : .. XP_005 KLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 DSLKTKQNMPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKK . :. : ..: .:..: . : : . .: :. ..:: .: ... :. .:.. XP_005 SELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLRE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 FKDQLQADRKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNH :. .: : XP_005 FQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLG 300 310 320 330 340 350 >>XP_005249431 (OMIM: 600830) PREDICTED: tripartite moti (539 aa) initn: 596 init1: 360 opt: 637 Z-score: 461.3 bits: 94.7 E(85289): 5.9e-19 Smith-Waterman score: 637; 34.7% identity (65.6% similar) in 308 aa overlap (1-300:1-307) 10 20 30 40 50 60 pF1KB0 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV ::.. . .:.::: : :::: :. :::::::: :: .: :.. : . ::::: XP_005 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 RKNAIRFNSLLRNLVEKIQAL------QASEVQSKRKEAT-CPRHQEMFHYFCEDDGKFL .:. :: : .:::.:. : : .:: ....: : ::.: .::.::::::.: XP_005 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 CFVCRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQ-VKAQGVHRVDVFTD : .::::..:. :.. :.:.::: .. .: .....:. .... .: .:.: . . XP_005 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLR-RDRDKIQGFQAKGEADILAALK 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 QVEHEKQRILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLV ... ..: :..::: :: :.:... :: .. : .: ::. ... . .: : .. XP_005 KLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 DSLKTKQNMPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKK . :. : ..: .:..: . : : . .: :. ..:: .: ... :. .:.. XP_005 SELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLRE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 FKDQLQADRKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNH :. .: : XP_005 FQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLG 300 310 320 330 340 350 >>XP_005249435 (OMIM: 600830) PREDICTED: tripartite moti (539 aa) initn: 596 init1: 360 opt: 637 Z-score: 461.3 bits: 94.7 E(85289): 5.9e-19 Smith-Waterman score: 637; 34.7% identity (65.6% similar) in 308 aa overlap (1-300:1-307) 10 20 30 40 50 60 pF1KB0 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV ::.. . .:.::: : :::: :. :::::::: :: .: :.. : . ::::: XP_005 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 RKNAIRFNSLLRNLVEKIQAL------QASEVQSKRKEAT-CPRHQEMFHYFCEDDGKFL .:. :: : .:::.:. : : .:: ....: : ::.: .::.::::::.: XP_005 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 CFVCRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQ-VKAQGVHRVDVFTD : .::::..:. :.. :.:.::: .. .: .....:. .... .: .:.: . . XP_005 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLR-RDRDKIQGFQAKGEADILAALK 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 QVEHEKQRILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLV ... ..: :..::: :: :.:... :: .. : .: ::. ... . .: : .. XP_005 KLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 DSLKTKQNMPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKK . :. : ..: .:..: . : : . .: :. ..:: .: ... :. .:.. XP_005 SELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLRE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 FKDQLQADRKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNH :. .: : XP_005 FQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLG 300 310 320 330 340 350 >>XP_005249434 (OMIM: 600830) PREDICTED: tripartite moti (539 aa) initn: 596 init1: 360 opt: 637 Z-score: 461.3 bits: 94.7 E(85289): 5.9e-19 Smith-Waterman score: 637; 34.7% identity (65.6% similar) in 308 aa overlap (1-300:1-307) 10 20 30 40 50 60 pF1KB0 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV ::.. . .:.::: : :::: :. :::::::: :: .: :.. : . ::::: XP_005 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 RKNAIRFNSLLRNLVEKIQAL------QASEVQSKRKEAT-CPRHQEMFHYFCEDDGKFL .:. :: : .:::.:. : : .:: ....: : ::.: .::.::::::.: XP_005 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 CFVCRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQ-VKAQGVHRVDVFTD : .::::..:. :.. :.:.::: .. .: .....:. .... .: .:.: . . XP_005 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLR-RDRDKIQGFQAKGEADILAALK 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 QVEHEKQRILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLV ... ..: :..::: :: :.:... :: .. : .: ::. ... . .: : .. XP_005 KLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVI 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 DSLKTKQNMPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKK . :. : ..: .:..: . : : . .: :. ..:: .: ... :. .:.. XP_005 SELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLRE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 FKDQLQADRKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNH :. .: : XP_005 FQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLG 300 310 320 330 340 350 425 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:30:30 2016 done: Sat Nov 5 17:30:32 2016 Total Scan time: 8.140 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]