FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0968, 431 aa
1>>>pF1KB0968 431 - 431 aa - 431 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4915+/-0.000384; mu= -2.1513+/- 0.024
mean_var=564.5640+/-128.424, 0's: 0 Z-trim(125.7): 785 B-trim: 2748 in 1/61
Lambda= 0.053978
statistics sampled from 48659 (50023) to 48659 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.843), E-opt: 0.2 (0.587), width: 16
Scan time: 11.020
The best scores are: opt bits E(85289)
NP_690599 (OMIM: 606633,613849) transcription fact ( 431) 3097 255.5 1.9e-67
NP_001166938 (OMIM: 606633,613849) transcription f ( 431) 3097 255.5 1.9e-67
XP_011536202 (OMIM: 606633,613849) PREDICTED: tran ( 413) 2986 246.8 7.6e-65
NP_001287766 (OMIM: 606633,613849) transcription f ( 413) 2986 246.8 7.6e-65
NP_954871 (OMIM: 608613) transcription factor Sp6 ( 376) 813 77.5 6.3e-14
XP_006722178 (OMIM: 608613) PREDICTED: transcripti ( 376) 813 77.5 6.3e-14
NP_001245177 (OMIM: 608613) transcription factor S ( 376) 813 77.5 6.3e-14
NP_945194 (OMIM: 608306) transcription factor Sp8 ( 490) 808 77.3 9.6e-14
NP_874359 (OMIM: 608306) transcription factor Sp8 ( 508) 808 77.3 9.7e-14
NP_001313472 (OMIM: 600540) transcription factor S ( 471) 618 62.5 2.7e-09
NP_001313471 (OMIM: 600540) transcription factor S ( 767) 618 62.8 3.5e-09
XP_005249885 (OMIM: 600540) PREDICTED: transcripti ( 767) 618 62.8 3.5e-09
NP_003103 (OMIM: 600540) transcription factor Sp4 ( 784) 618 62.8 3.5e-09
NP_001003845 (OMIM: 609391) transcription factor S ( 398) 605 61.4 4.9e-09
XP_005246599 (OMIM: 609391) PREDICTED: transcripti ( 442) 605 61.4 5.2e-09
XP_011509461 (OMIM: 609391) PREDICTED: transcripti ( 454) 605 61.5 5.2e-09
NP_001238754 (OMIM: 189906) transcription factor S ( 737) 606 61.8 6.5e-09
NP_003100 (OMIM: 189906) transcription factor Sp1 ( 778) 606 61.9 6.7e-09
XP_011536998 (OMIM: 189906) PREDICTED: transcripti ( 778) 606 61.9 6.7e-09
NP_612482 (OMIM: 189906) transcription factor Sp1 ( 785) 606 61.9 6.8e-09
NP_001017371 (OMIM: 601804) transcription factor S ( 713) 590 60.6 1.5e-08
NP_001166183 (OMIM: 601804) transcription factor S ( 778) 590 60.6 1.6e-08
NP_003102 (OMIM: 601804) transcription factor Sp3 ( 781) 590 60.6 1.6e-08
NP_057079 (OMIM: 605328,612001) Krueppel-like fact ( 288) 515 54.2 5.2e-07
NP_003101 (OMIM: 601801) transcription factor Sp2 ( 613) 522 55.2 5.5e-07
XP_006722088 (OMIM: 601801) PREDICTED: transcripti ( 660) 522 55.2 5.7e-07
XP_006722090 (OMIM: 601801) PREDICTED: transcripti ( 660) 522 55.2 5.7e-07
XP_016880457 (OMIM: 601801) PREDICTED: transcripti ( 660) 522 55.2 5.7e-07
XP_016880458 (OMIM: 601801) PREDICTED: transcripti ( 660) 522 55.2 5.7e-07
XP_011523444 (OMIM: 601801) PREDICTED: transcripti ( 660) 522 55.2 5.7e-07
XP_011523445 (OMIM: 601801) PREDICTED: transcripti ( 660) 522 55.2 5.7e-07
XP_006722089 (OMIM: 601801) PREDICTED: transcripti ( 660) 522 55.2 5.7e-07
XP_006722086 (OMIM: 601801) PREDICTED: transcripti ( 667) 522 55.2 5.8e-07
XP_011523442 (OMIM: 601801) PREDICTED: transcripti ( 717) 522 55.3 6e-07
XP_011523441 (OMIM: 601801) PREDICTED: transcripti ( 727) 522 55.3 6e-07
XP_011523440 (OMIM: 601801) PREDICTED: transcripti ( 760) 522 55.3 6.2e-07
XP_011523439 (OMIM: 601801) PREDICTED: transcripti ( 768) 522 55.3 6.2e-07
XP_011523438 (OMIM: 601801) PREDICTED: transcripti ( 771) 522 55.3 6.3e-07
NP_114124 (OMIM: 606139) Krueppel-like factor 16 [ ( 252) 500 52.9 1.1e-06
NP_057354 (OMIM: 602016) Krueppel-like factor 2 [H ( 355) 499 53.1 1.4e-06
NP_619638 (OMIM: 609393) Krueppel-like factor 14 [ ( 323) 475 51.1 4.8e-06
XP_011513788 (OMIM: 600540) PREDICTED: transcripti ( 711) 481 52.1 5.5e-06
XP_005249886 (OMIM: 600540) PREDICTED: transcripti ( 706) 470 51.2 9.9e-06
XP_005247457 (OMIM: 606465) PREDICTED: Krueppel-li ( 416) 463 50.4 1.1e-05
NP_054798 (OMIM: 606465) Krueppel-like factor 15 [ ( 416) 463 50.4 1.1e-05
XP_011511045 (OMIM: 606465) PREDICTED: Krueppel-li ( 435) 463 50.4 1.1e-05
XP_011539002 (OMIM: 609602) PREDICTED: Krueppel-li ( 352) 452 49.4 1.8e-05
NP_775755 (OMIM: 609602) Krueppel-like factor 17 [ ( 389) 452 49.5 1.9e-05
NP_001197 (OMIM: 602902) Krueppel-like factor 9 [H ( 244) 446 48.7 2e-05
XP_011525944 (OMIM: 111150,600599,613566,613673) P ( 324) 440 48.4 3.2e-05
>>NP_690599 (OMIM: 606633,613849) transcription factor S (431 aa)
initn: 3097 init1: 3097 opt: 3097 Z-score: 1331.7 bits: 255.5 E(85289): 1.9e-67
Smith-Waterman score: 3097; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KB0 MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 GDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 CLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 CLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 TLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 TLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 EGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 EGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 CGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 CGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 KRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPG
370 380 390 400 410 420
430
pF1KB0 GSPEQSNLLEI
:::::::::::
NP_690 GSPEQSNLLEI
430
>>NP_001166938 (OMIM: 606633,613849) transcription facto (431 aa)
initn: 3097 init1: 3097 opt: 3097 Z-score: 1331.7 bits: 255.5 E(85289): 1.9e-67
Smith-Waterman score: 3097; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KB0 MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 CLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 TLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 EGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 CGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 KRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPG
370 380 390 400 410 420
430
pF1KB0 GSPEQSNLLEI
:::::::::::
NP_001 GSPEQSNLLEI
430
>>XP_011536202 (OMIM: 606633,613849) PREDICTED: transcri (413 aa)
initn: 2986 init1: 2986 opt: 2986 Z-score: 1285.2 bits: 246.8 E(85289): 7.6e-65
Smith-Waterman score: 2986; 100.0% identity (100.0% similar) in 413 aa overlap (19-431:1-413)
10 20 30 40 50 60
pF1KB0 MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTM
::::::::::::::::::::::::::::::::::::::::::
XP_011 MLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTM
10 20 30 40
70 80 90 100 110 120
pF1KB0 GDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB0 CLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQG
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB0 TLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB0 EGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPG
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB0 CGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCS
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB0 KRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPG
350 360 370 380 390 400
430
pF1KB0 GSPEQSNLLEI
:::::::::::
XP_011 GSPEQSNLLEI
410
>>NP_001287766 (OMIM: 606633,613849) transcription facto (413 aa)
initn: 2986 init1: 2986 opt: 2986 Z-score: 1285.2 bits: 246.8 E(85289): 7.6e-65
Smith-Waterman score: 2986; 100.0% identity (100.0% similar) in 413 aa overlap (19-431:1-413)
10 20 30 40 50 60
pF1KB0 MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTM
::::::::::::::::::::::::::::::::::::::::::
NP_001 MLTAACSKFGGSSPLRDSTTLGKAGTKKPYSVGSDLSASKTM
10 20 30 40
70 80 90 100 110 120
pF1KB0 GDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDAYPAPFTSTNGLLSPAGSPPAPTSGYANDYPPFSHSFPGPTGTQDPGLLVPKGHSSSD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB0 CLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLPSVYTSLDMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQG
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB0 TLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDVYKPKAVGNSGQL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB0 EGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGSGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPG
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB0 CGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCS
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB0 KRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPG
350 360 370 380 390 400
430
pF1KB0 GSPEQSNLLEI
:::::::::::
NP_001 GSPEQSNLLEI
410
>>NP_954871 (OMIM: 608613) transcription factor Sp6 [Hom (376 aa)
initn: 700 init1: 526 opt: 813 Z-score: 371.0 bits: 77.5 E(85289): 6.3e-14
Smith-Waterman score: 857; 40.7% identity (59.0% similar) in 398 aa overlap (59-427:8-376)
30 40 50 60 70 80
pF1KB0 GSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYP-APFTSTNGL-LSPAGSPPAPTS
..:. . :: .: : :.: . . ::
NP_954 MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTS
10 20 30
90 100 110 120
pF1KB0 GYANDYP-PFS----HSFP-GPTGTQDPGLLVPKGHSSSDC---------LPSVYTSL--
:.::: :.. .:.: :: . : .: . : : :. ...:
NP_954 PEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB0 -DMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQ
::.: : ::.. : :: :::.::: .:. . ::.: :.:..
NP_954 PDMSHHYESWFRP-TH------PGAEDGSWWDLHPGTSWMDLPH-----TQGAL-TSPGH
100 110 120 130 140
190 200 210 220 230 240
pF1KB0 P-PLNPQLPTYPSDFAPLNPAPYPAPHLLQP--GPQHVL-PQDVYKPKAVG--NSGQLEG
: :. : : .: : :.: : : : : ::.: : : : :. .: :..
NP_954 PGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQHLLGPPDGAKALEVAAPESQGLDS
150 160 170 180 190 200
250 260 270 280 290
pF1KB0 S-GGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAA--GLRKKPIHSCHIP
: :: :.:. . ..:.. : :::: : ::::: . : .:: .:.::::
NP_954 SLDGAARPKGSRRSVP-----RSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIP
210 220 230 240 250
300 310 320 330 340 350
pF1KB0 GCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLC
::::.:.:.::::::::::.:.::::::::::::::::::::.::..::: ::: : .:
NP_954 GCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVC
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB0 SKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAP
:. : :::::.::..:: : :: . : ..:: .:. . .: .. . :
NP_954 SRVFMRSDHLAKHMKTH---------EGAKEEAAGAASGEGKAGGAVEPPGGKGKREAE-
320 330 340 350 360
420 430
pF1KB0 GGSPEQSNLLEI
:: ::
NP_954 -GSVAPSN
370
>>XP_006722178 (OMIM: 608613) PREDICTED: transcription f (376 aa)
initn: 700 init1: 526 opt: 813 Z-score: 371.0 bits: 77.5 E(85289): 6.3e-14
Smith-Waterman score: 857; 40.7% identity (59.0% similar) in 398 aa overlap (59-427:8-376)
30 40 50 60 70 80
pF1KB0 GSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYP-APFTSTNGL-LSPAGSPPAPTS
..:. . :: .: : :.: . . ::
XP_006 MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTS
10 20 30
90 100 110 120
pF1KB0 GYANDYP-PFS----HSFP-GPTGTQDPGLLVPKGHSSSDC---------LPSVYTSL--
:.::: :.. .:.: :: . : .: . : : :. ...:
XP_006 PEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB0 -DMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQ
::.: : ::.. : :: :::.::: .:. . ::.: :.:..
XP_006 PDMSHHYESWFRP-TH------PGAEDGSWWDLHPGTSWMDLPH-----TQGAL-TSPGH
100 110 120 130 140
190 200 210 220 230 240
pF1KB0 P-PLNPQLPTYPSDFAPLNPAPYPAPHLLQP--GPQHVL-PQDVYKPKAVG--NSGQLEG
: :. : : .: : :.: : : : : ::.: : : : :. .: :..
XP_006 PGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQHLLGPPDGAKALEVAAPESQGLDS
150 160 170 180 190 200
250 260 270 280 290
pF1KB0 S-GGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAA--GLRKKPIHSCHIP
: :: :.:. . ..:.. : :::: : ::::: . : .:: .:.::::
XP_006 SLDGAARPKGSRRSVP-----RSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIP
210 220 230 240 250
300 310 320 330 340 350
pF1KB0 GCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLC
::::.:.:.::::::::::.:.::::::::::::::::::::.::..::: ::: : .:
XP_006 GCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVC
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB0 SKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAP
:. : :::::.::..:: : :: . : ..:: .:. . .: .. . :
XP_006 SRVFMRSDHLAKHMKTH---------EGAKEEAAGAASGEGKAGGAVEPPGGKGKREAE-
320 330 340 350 360
420 430
pF1KB0 GGSPEQSNLLEI
:: ::
XP_006 -GSVAPSN
370
>>NP_001245177 (OMIM: 608613) transcription factor Sp6 [ (376 aa)
initn: 700 init1: 526 opt: 813 Z-score: 371.0 bits: 77.5 E(85289): 6.3e-14
Smith-Waterman score: 857; 40.7% identity (59.0% similar) in 398 aa overlap (59-427:8-376)
30 40 50 60 70 80
pF1KB0 GSSPLRDSTTLGKAGTKKPYSVGSDLSASKTMGDAYP-APFTSTNGL-LSPAGSPPAPTS
..:. . :: .: : :.: . . ::
NP_001 MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTS
10 20 30
90 100 110 120
pF1KB0 GYANDYP-PFS----HSFP-GPTGTQDPGLLVPKGHSSSDC---------LPSVYTSL--
:.::: :.. .:.: :: . : .: . : : :. ...:
NP_001 PEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB0 -DMTHPYGSWYKAGIHAGISPGPGNTPTPWWDMHPGGNWLGGGQGQGDGLQGTLPTGPAQ
::.: : ::.. : :: :::.::: .:. . ::.: :.:..
NP_001 PDMSHHYESWFRP-TH------PGAEDGSWWDLHPGTSWMDLPH-----TQGAL-TSPGH
100 110 120 130 140
190 200 210 220 230 240
pF1KB0 P-PLNPQLPTYPSDFAPLNPAPYPAPHLLQP--GPQHVL-PQDVYKPKAVG--NSGQLEG
: :. : : .: : :.: : : : : ::.: : : : :. .: :..
NP_001 PGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQHLLGPPDGAKALEVAAPESQGLDS
150 160 170 180 190 200
250 260 270 280 290
pF1KB0 S-GGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAA--GLRKKPIHSCHIP
: :: :.:. . ..:.. : :::: : ::::: . : .:: .:.::::
NP_001 SLDGAARPKGSRRSVP-----RSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIP
210 220 230 240 250
300 310 320 330 340 350
pF1KB0 GCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLC
::::.:.:.::::::::::.:.::::::::::::::::::::.::..::: ::: : .:
NP_001 GCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVC
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB0 SKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAP
:. : :::::.::..:: : :: . : ..:: .:. . .: .. . :
NP_001 SRVFMRSDHLAKHMKTH---------EGAKEEAAGAASGEGKAGGAVEPPGGKGKREAE-
320 330 340 350 360
420 430
pF1KB0 GGSPEQSNLLEI
:: ::
NP_001 -GSVAPSN
370
>>NP_945194 (OMIM: 608306) transcription factor Sp8 isof (490 aa)
initn: 702 init1: 702 opt: 808 Z-score: 367.8 bits: 77.3 E(85289): 9.6e-14
Smith-Waterman score: 993; 40.2% identity (64.3% similar) in 440 aa overlap (13-430:63-490)
10 20 30 40
pF1KB0 MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKA
:.: : .:: . .... . :: . : .
NP_945 WKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGS
40 50 60 70 80 90
50 60 70 80 90
pF1KB0 GTKKPYSVGSDLSASKTMGDAYPA---PFTSTNGLL-SPAGSPPAPTSGYANDYPPFSHS
.. .:. :. .:. . . : : ::.. ... .:. : . .: .. .::
NP_945 PGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHS
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB0 FPGPTGTQDPGLLVPKGHSSSDCLPSVYTSLDMTHPYGSWYKAGIHAGISPGP--GNT-P
:...: ... : :.: : : ..: . :.::: ::.: . : :.. . :..
NP_945 ---QDGSHQP-VFISKVHTSVDGLQGIYPRVGMAHPYESWFKPS-HPGLGAAGEVGSAGA
160 170 180 190 200
160 170 180 190 200 210
pF1KB0 TPWWDMHPGGNWLG-GGQGQGDGLQGTL-PT-GPAQPPLNPQLPTYPSDFAPLNPAPYPA
. :::. :..:. . ... .: :.: :. : : :. : : ::.. :. . . .
NP_945 SSWWDV--GAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSAFSS
210 220 230 240 250 260
220 230 240 250 260
pF1KB0 ---PHLLQPGPQHVLPQDVYKPKAVGN-----SGQLEGSGGAKPPRGASTGGSGGYGGSG
:::.:. ::.. : .:: :. . : :.::. : :. .:. .:.
NP_945 GASSHLLSPAGQHLM--DGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAPLGGSPRSSA
270 280 290 300 310 320
270 280 290 300 310 320
pF1KB0 ---AGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPGCGKVYGKASHLKAHLRWHTGE
.::..:::::::: :::: :.:.::.: .::::::::::::::.:::::::::::::
NP_945 RRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGE
330 340 350 360 370 380
330 340 350 360 370 380
pF1KB0 RPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCSKRFTRSDHLSKHQRTHGEPGP
::::::::::::::::::::.::.:::: ::.:.: .:.::: :::::::: .::. :
NP_945 RPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGGGG
390 400 410 420 430 440
390 400 410 420 430
pF1KB0 GPPPSGPKELGEGRSTGEEEASQTPRPSASPA-TPEKAPGGSPEQSNLLEI
: .: : : . : . :. .. : .:: : . : ::
NP_945 GGGSAGS---GSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE
450 460 470 480 490
>>NP_874359 (OMIM: 608306) transcription factor Sp8 isof (508 aa)
initn: 850 init1: 702 opt: 808 Z-score: 367.6 bits: 77.3 E(85289): 9.7e-14
Smith-Waterman score: 993; 40.2% identity (64.3% similar) in 440 aa overlap (13-430:81-508)
10 20 30 40
pF1KB0 MASSLLEEEVHYGSSPLAMLTAACSKFGGSSPLRDSTTLGKA
:.: : .:: . .... . :: . : .
NP_874 WKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGS
60 70 80 90 100 110
50 60 70 80 90
pF1KB0 GTKKPYSVGSDLSASKTMGDAYPA---PFTSTNGLL-SPAGSPPAPTSGYANDYPPFSHS
.. .:. :. .:. . . : : ::.. ... .:. : . .: .. .::
NP_874 PGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHS
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB0 FPGPTGTQDPGLLVPKGHSSSDCLPSVYTSLDMTHPYGSWYKAGIHAGISPGP--GNT-P
:...: ... : :.: : : ..: . :.::: ::.: . : :.. . :..
NP_874 ---QDGSHQP-VFISKVHTSVDGLQGIYPRVGMAHPYESWFKPS-HPGLGAAGEVGSAGA
180 190 200 210 220
160 170 180 190 200 210
pF1KB0 TPWWDMHPGGNWLG-GGQGQGDGLQGTL-PT-GPAQPPLNPQLPTYPSDFAPLNPAPYPA
. :::. :..:. . ... .: :.: :. : : :. : : ::.. :. . . .
NP_874 SSWWDV--GAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSAFSS
230 240 250 260 270 280
220 230 240 250 260
pF1KB0 ---PHLLQPGPQHVLPQDVYKPKAVGN-----SGQLEGSGGAKPPRGASTGGSGGYGGSG
:::.:. ::.. : .:: :. . : :.::. : :. .:. .:.
NP_874 GASSHLLSPAGQHLM--DGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAPLGGSPRSSA
290 300 310 320 330 340
270 280 290 300 310 320
pF1KB0 ---AGRSSCDCPNCQELERLGAAAAGLRKKPIHSCHIPGCGKVYGKASHLKAHLRWHTGE
.::..:::::::: :::: :.:.::.: .::::::::::::::.:::::::::::::
NP_874 RRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGE
350 360 370 380 390 400
330 340 350 360 370 380
pF1KB0 RPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCSKRFTRSDHLSKHQRTHGEPGP
::::::::::::::::::::.::.:::: ::.:.: .:.::: :::::::: .::. :
NP_874 RPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGGGG
410 420 430 440 450 460
390 400 410 420 430
pF1KB0 GPPPSGPKELGEGRSTGEEEASQTPRPSASPA-TPEKAPGGSPEQSNLLEI
: .: : : . : . :. .. : .:: : . : ::
NP_874 GGGSAGS---GSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE
470 480 490 500
>>NP_001313472 (OMIM: 600540) transcription factor Sp4 i (471 aa)
initn: 567 init1: 529 opt: 618 Z-score: 288.0 bits: 62.5 E(85289): 2.7e-09
Smith-Waterman score: 618; 46.0% identity (62.9% similar) in 224 aa overlap (217-430:249-469)
190 200 210 220 230 240
pF1KB0 AQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHV-LPQDVYKPKAVGNSGQLEGSGG
: : . : . : . : .:. .: ... :
NP_001 NLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIG
220 230 240 250 260 270
250 260 270 280 290
pF1KB0 AKPP---------RGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGLRKKPIHSC
: : .: .:. . :. : .:.::::.: : :. : :: : :
NP_001 AVSPDQLTQVHLQQGQQTSDQEVQPGKRLRRVACSCPNCREGEGRGSNEPG--KKKQHIC
280 290 300 310 320 330
300 310 320 330 340 350
pF1KB0 HIPGCGKVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTC
:: ::::::::.:::.::::::::::::.:::.::::::::::::.:: :::: ::.: :
NP_001 HIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFEC
340 350 360 370 380 390
360 370 380 390 400 410
pF1KB0 LLCSKRFTRSDHLSKHQRTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPE
::::: :::::::: .:: . : . :: :. :. .:: . : .
NP_001 PECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSS-VTEVLGSPRIVTVAAISQ
400 410 420 430 440 450
420 430
pF1KB0 KAPGGSPEQSNLLEI
. ..:. :. .:
NP_001 DSNPATPNVSTNMEEF
460 470
431 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:33:20 2016 done: Sat Nov 5 17:33:22 2016
Total Scan time: 11.020 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]