FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0971, 209 aa
1>>>pF1KB0971 209 - 209 aa - 209 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0844+/-0.000273; mu= 16.0942+/- 0.017
mean_var=79.9029+/-15.625, 0's: 0 Z-trim(120.4): 21 B-trim: 0 in 0/54
Lambda= 0.143481
statistics sampled from 35482 (35511) to 35482 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.416), width: 16
Scan time: 6.820
The best scores are: opt bits E(85289)
XP_011540450 (OMIM: 611043) PREDICTED: protein lin ( 209) 1462 311.2 7.8e-85
NP_078950 (OMIM: 611043) protein lin-28 homolog A ( 209) 1462 311.2 7.8e-85
NP_001004317 (OMIM: 611044) protein lin-28 homolog ( 250) 912 197.4 1.7e-50
XP_011534120 (OMIM: 611044) PREDICTED: protein lin ( 258) 912 197.4 1.7e-50
XP_006715540 (OMIM: 611044) PREDICTED: protein lin ( 269) 912 197.4 1.8e-50
NP_057066 (OMIM: 611447) Y-box-binding protein 2 [ ( 364) 229 56.2 8e-08
XP_016875611 (OMIM: 603437) PREDICTED: Y-box-bindi ( 369) 227 55.8 1.1e-07
NP_003642 (OMIM: 603437) Y-box-binding protein 3 i ( 372) 227 55.8 1.1e-07
XP_011519173 (OMIM: 603437) PREDICTED: Y-box-bindi ( 200) 222 54.5 1.4e-07
XP_016875612 (OMIM: 603437) PREDICTED: Y-box-bindi ( 300) 222 54.7 1.9e-07
NP_001138898 (OMIM: 603437) Y-box-binding protein ( 303) 222 54.7 1.9e-07
NP_004550 (OMIM: 154030) nuclease-sensitive elemen ( 324) 203 50.7 3.1e-06
>>XP_011540450 (OMIM: 611043) PREDICTED: protein lin-28 (209 aa)
initn: 1462 init1: 1462 opt: 1462 Z-score: 1644.0 bits: 311.2 E(85289): 7.8e-85
Smith-Waterman score: 1462; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209)
10 20 30 40 50 60
pF1KB0 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 RAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 ERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQ
130 140 150 160 170 180
190 200
pF1KB0 GPSAQGKPTYFREEEEEIHSPTLLPEAQN
:::::::::::::::::::::::::::::
XP_011 GPSAQGKPTYFREEEEEIHSPTLLPEAQN
190 200
>>NP_078950 (OMIM: 611043) protein lin-28 homolog A [Hom (209 aa)
initn: 1462 init1: 1462 opt: 1462 Z-score: 1644.0 bits: 311.2 E(85289): 7.8e-85
Smith-Waterman score: 1462; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209)
10 20 30 40 50 60
pF1KB0 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 RAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 RAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 ERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 ERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQ
130 140 150 160 170 180
190 200
pF1KB0 GPSAQGKPTYFREEEEEIHSPTLLPEAQN
:::::::::::::::::::::::::::::
NP_078 GPSAQGKPTYFREEEEEIHSPTLLPEAQN
190 200
>>NP_001004317 (OMIM: 611044) protein lin-28 homolog B [ (250 aa)
initn: 915 init1: 861 opt: 912 Z-score: 1027.7 bits: 197.4 E(85289): 1.7e-50
Smith-Waterman score: 912; 68.5% identity (78.7% similar) in 197 aa overlap (11-205:4-192)
10 20 30 40 50 60
pF1KB0 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTA
:: .:.. : : . :: : .: :.:.:.: ::::::::::::.::
NP_001 MAEGGASKGGGEEPGKLPEPA---EEESQVLRGTGHCKWFNVRMGFGFISMIN
10 20 30 40 50
70 80 90 100 110 120
pF1KB0 RAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGS
: : :: ::::::::::: ::::::::::: ::::::::.::::::::::::: :.::
NP_001 REGSPLDIPVDVFVHQSKLFMEGFRSLKEGEPVEFTFKKSSKGLESIRVTGPGGSPCLGS
60 70 80 90 100 110
130 140 150 160 170
pF1KB0 ERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLK--A
:::::::..:::. ::::::::::::::::::.:::::::::.:::: ::::.:: : :
NP_001 ERRPKGKTLQKRKPKGDRCYNCGGLDHHAKECSLPPQPKKCHYCQSIMHMVANCPHKNVA
120 130 140 150 160 170
180 190 200
pF1KB0 QQGPSAQGKPTYFREEEEEIHSPTLLPEAQN
: :.:: :.: : . ::
NP_001 QPPASSQG-----RQEAESQPCTSTLPREVGGGHGCTSPPFPQEARAEISERSGRSPQEA
180 190 200 210 220
>>XP_011534120 (OMIM: 611044) PREDICTED: protein lin-28 (258 aa)
initn: 915 init1: 861 opt: 912 Z-score: 1027.5 bits: 197.4 E(85289): 1.7e-50
Smith-Waterman score: 912; 68.5% identity (78.7% similar) in 197 aa overlap (11-205:12-200)
10 20 30 40 50
pF1KB0 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMT
:: .:.. : : . :: : .: :.:.:.: ::::::::::::.::
XP_011 MRSFNQVSSAPGGASKGGGEEPGKLPEPA---EEESQVLRGTGHCKWFNVRMGFGFISMI
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 ARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIG
: : :: ::::::::::: ::::::::::: ::::::::.::::::::::::: :.:
XP_011 NREGSPLDIPVDVFVHQSKLFMEGFRSLKEGEPVEFTFKKSSKGLESIRVTGPGGSPCLG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 SERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLK--
::::::::..:::. ::::::::::::::::::.:::::::::.:::: ::::.:: :
XP_011 SERRPKGKTLQKRKPKGDRCYNCGGLDHHAKECSLPPQPKKCHYCQSIMHMVANCPHKNV
120 130 140 150 160 170
180 190 200
pF1KB0 AQQGPSAQGKPTYFREEEEEIHSPTLLPEAQN
:: :.:: :.: : . ::
XP_011 AQPPASSQG-----RQEAESQPCTSTLPREVGGGHGCTSPPFPQEARAEISERSGRSPQE
180 190 200 210 220 230
>>XP_006715540 (OMIM: 611044) PREDICTED: protein lin-28 (269 aa)
initn: 915 init1: 861 opt: 912 Z-score: 1027.3 bits: 197.4 E(85289): 1.8e-50
Smith-Waterman score: 912; 68.5% identity (78.7% similar) in 197 aa overlap (11-205:23-211)
10 20 30 40
pF1KB0 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFN
:: .:.. : : . :: : .: :.:.:.: :::::
XP_006 MSHRRQVLQKRMRSFNQVSSAPGGASKGGGEEPGKLPEPA---EEESQVLRGTGHCKWFN
10 20 30 40 50
50 60 70 80 90 100
pF1KB0 VRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIR
:::::::.:: : : :: ::::::::::: ::::::::::: ::::::::.:::::::
XP_006 VRMGFGFISMINREGSPLDIPVDVFVHQSKLFMEGFRSLKEGEPVEFTFKKSSKGLESIR
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB0 VTGPGGVFCIGSERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSIS
:::::: :.:::::::::..:::. ::::::::::::::::::.:::::::::.::::
XP_006 VTGPGGSPCLGSERRPKGKTLQKRKPKGDRCYNCGGLDHHAKECSLPPQPKKCHYCQSIM
120 130 140 150 160 170
170 180 190 200
pF1KB0 HMVASCPLK--AQQGPSAQGKPTYFREEEEEIHSPTLLPEAQN
::::.:: : :: :.:: :.: : . ::
XP_006 HMVANCPHKNVAQPPASSQG-----RQEAESQPCTSTLPREVGGGHGCTSPPFPQEARAE
180 190 200 210 220 230
XP_006 ISERSGRSPQEASSTKSSIAPEEQSKKGPSVQKRKKT
240 250 260
>>NP_057066 (OMIM: 611447) Y-box-binding protein 2 [Homo (364 aa)
initn: 271 init1: 121 opt: 229 Z-score: 261.5 bits: 56.2 E(85289): 8e-08
Smith-Waterman score: 229; 36.6% identity (60.4% similar) in 134 aa overlap (3-131:59-182)
10 20 30
pF1KB0 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAA
:. ... :. : :. .: :: : :
NP_057 VVPVPAGEPQKGGGAGGGGGAASGPAAGTPSAPGSRTPGNPATAVSGTP--APP-ARSQA
30 40 50 60 70 80
40 50 60 70 80
pF1KB0 DEPQL-LHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEG----FRSL
:.: : .. : :::::: :.::.. . : ::::::. .. .. .::.
NP_057 DKPVLAIQVLGTVKWFNVRNGYGFINRN-------DTKEDVFVHQTAIKRNNPRKFLRSV
90 100 110 120 130
90 100 110 120 130 140
pF1KB0 KEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKSMQKRRSKGDRCYNCGGLDH
.::.::: .. :: :. ::::::: ::. :. .. ..
NP_057 GDGETVEFDVVEGEKGAEATNVTGPGGVPVKGSRYAPNRRKSRRFIPRPPSVAPPPMVAE
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB0 HAKECKLPPQPKKCHFCQSISHMVASCPLKAQQGPSAQGKPTYFREEEEEIHSPTLLPEA
NP_057 IPSAGTGPGSKGERAEDSGQRPRRWCPPPFFYRRRFVRGPRPPNQQQPIEGTDRVEPKET
200 210 220 230 240 250
>>XP_016875611 (OMIM: 603437) PREDICTED: Y-box-binding p (369 aa)
initn: 222 init1: 103 opt: 227 Z-score: 259.2 bits: 55.8 E(85289): 1.1e-07
Smith-Waterman score: 227; 36.7% identity (54.7% similar) in 139 aa overlap (10-140:64-192)
10 20 30
pF1KB0 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLH
: : : :: : . ::: . . ..:
XP_016 SPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEKKVLATKVL-
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB0 GAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEG----FRSLKEGEAVEF
: :::::: :.::.. . : ::::::. .. .. .::. .::.:::
XP_016 --GTVKWFNVRNGYGFINRN-------DTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEF
100 110 120 130 140
100 110 120 130 140 150
pF1KB0 TFKKSAKGLESIRVTGPGGVFCIGS----ERRPKGKSMQKRRSKGDRCYNCGGLDHHAKE
.. :: :. :::: :: :: .:: ... :: : :
XP_016 DVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGS
150 160 170 180 190 200
160 170 180 190 200
pF1KB0 CKLPPQPKKCHFCQSISHMVASCPLKAQQGPSAQGKPTYFREEEEEIHSPTLLPEAQN
XP_016 SEGFDPPATDRQFSGARNQLRRPQYRPQYRQRRFPPYHVGQTFDRRSRVLPHPNRIQAGE
210 220 230 240 250 260
>>NP_003642 (OMIM: 603437) Y-box-binding protein 3 isofo (372 aa)
initn: 222 init1: 103 opt: 227 Z-score: 259.1 bits: 55.8 E(85289): 1.1e-07
Smith-Waterman score: 227; 36.7% identity (54.7% similar) in 139 aa overlap (10-140:64-192)
10 20 30
pF1KB0 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLH
: : : :: : . ::: . . ..:
NP_003 SPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEKKVLATKVL-
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB0 GAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEG----FRSLKEGEAVEF
: :::::: :.::.. . : ::::::. .. .. .::. .::.:::
NP_003 --GTVKWFNVRNGYGFINRN-------DTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEF
100 110 120 130 140
100 110 120 130 140 150
pF1KB0 TFKKSAKGLESIRVTGPGGVFCIGS----ERRPKGKSMQKRRSKGDRCYNCGGLDHHAKE
.. :: :. :::: :: :: .:: ... :: : :
NP_003 DVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGS
150 160 170 180 190 200
160 170 180 190 200
pF1KB0 CKLPPQPKKCHFCQSISHMVASCPLKAQQGPSAQGKPTYFREEEEEIHSPTLLPEAQN
NP_003 SEGFDPPATDRQFSGARNQLRRPQYRPQYRQRRFPPYHVGQTFDRRSRVLPHPNRIQAGE
210 220 230 240 250 260
>>XP_011519173 (OMIM: 603437) PREDICTED: Y-box-binding p (200 aa)
initn: 222 init1: 103 opt: 222 Z-score: 257.0 bits: 54.5 E(85289): 1.4e-07
Smith-Waterman score: 222; 36.8% identity (54.1% similar) in 133 aa overlap (10-138:64-185)
10 20 30
pF1KB0 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLH
: : : :: : . ::: . . ..:
XP_011 SPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEKKVLATKVL-
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB0 GAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEG----FRSLKEGEAVEF
: :::::: :.::.. . : ::::::. .. .. .::. .::.:::
XP_011 --GTVKWFNVRNGYGFINRN-------DTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEF
100 110 120 130 140
100 110 120 130 140 150
pF1KB0 TFKKSAKGLESIRVTGPGGVFCIGSERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLP
.. :: :. :::: :: :: : . .: : :
XP_011 DVVEGEKGAEAANVTGPDGVPVEGS-RYAADRRRYRRGYYGRRRGPPRNISDVWFNRR
150 160 170 180 190 200
160 170 180 190 200
pF1KB0 PQPKKCHFCQSISHMVASCPLKAQQGPSAQGKPTYFREEEEEIHSPTLLPEAQN
>>XP_016875612 (OMIM: 603437) PREDICTED: Y-box-binding p (300 aa)
initn: 222 init1: 103 opt: 222 Z-score: 254.7 bits: 54.7 E(85289): 1.9e-07
Smith-Waterman score: 223; 33.3% identity (50.0% similar) in 186 aa overlap (10-190:64-218)
10 20 30
pF1KB0 MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLH
: : : :: : . ::: . . ..:
XP_016 SPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEKKVLATKVL-
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB0 GAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEG----FRSLKEGEAVEF
: :::::: :.::.. . : ::::::. .. .. .::. .::.:::
XP_016 --GTVKWFNVRNGYGFINRN-------DTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEF
100 110 120 130 140
100 110 120 130 140 150
pF1KB0 TFKKSAKGLESIRVTGPGGVFCIGSERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLP
.. :: :. :::: :: :: : . .: : : . :
XP_016 DVVEGEKGAEAANVTGPDGVPVEGS-RYAADRRRYRRGYYGRR--------------RGP
150 160 170 180
160 170 180 190 200
pF1KB0 PQPKKCHFCQSISHMVASCPLKAQ-QGPSAQGKPTYFREEEEEIHSPTLLPEAQN
:. :..: . : :: ::: .. .:::
XP_016 PRNAG-----EIGEMKDGVPEGAQLQGP-VHRNPTYRPSRGPPRPRPAPAVGEAEDKENQ
190 200 210 220 230 240
XP_016 QATSGPNQPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTENPAPPTQQSSAE
250 260 270 280 290 300
209 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:34:33 2016 done: Sat Nov 5 17:34:34 2016
Total Scan time: 6.820 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]