Result of FASTA (omim) for
pF1KB0972
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0972, 437 aa
1>>>pF1KB0972 437 - 437 aa - 437 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6879+/-0.000382; mu= 12.3168+/- 0.024
mean_var=122.2763+/-23.885, 0's: 0 Z-trim(116.3): 12 B-trim: 0 in 0/57
Lambda= 0.115985
statistics sampled from 27354 (27364) to 27354 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.321), width: 16
Scan time: 7.660
The best scores are: opt bits E(85289)
NP_001395 (OMIM: 130593) elongation factor 1-gamma ( 437) 2977 509.3 7.9e-144
NP_006286 (OMIM: 192150) valine--tRNA ligase [Homo (1264) 433 83.9 2.5e-15
XP_005249419 (OMIM: 192150) PREDICTED: valine--tRN (1265) 429 83.3 4e-15
>>NP_001395 (OMIM: 130593) elongation factor 1-gamma [Ho (437 aa)
initn: 2977 init1: 2977 opt: 2977 Z-score: 2703.2 bits: 509.3 E(85289): 7.9e-144
Smith-Waterman score: 2977; 100.0% identity (100.0% similar) in 437 aa overlap (1-437:1-437)
10 20 30 40 50 60
pF1KB0 MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 FEGDDGFCVFESNAIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEGDDGFCVFESNAIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 MHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 RQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTPRKEKGSREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTPRKEKGSREE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 KQKPQAERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQKPQAERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DTLSVALPYFWEHFDKDGWSLWYSEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTLSVALPYFWEHFDKDGWSLWYSEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 ILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWE
370 380 390 400 410 420
430
pF1KB0 GAFQHVGKAFNQGKIFK
:::::::::::::::::
NP_001 GAFQHVGKAFNQGKIFK
430
>>NP_006286 (OMIM: 192150) valine--tRNA ligase [Homo sap (1264 aa)
initn: 326 init1: 237 opt: 433 Z-score: 396.1 bits: 83.9 E(85289): 2.5e-15
Smith-Waterman score: 447; 33.9% identity (60.8% similar) in 286 aa overlap (5-274:3-275)
10 20 30 40
pF1KB0 MAAGTLYT--YPENWRAFKALIAAQYS---------GAQVRVLSAPPHFHFGQTNRTPEF
:::. .:. . ...:::::.:. ::. :. :: :.:::
NP_006 MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPP-----PTSRTP--
10 20 30 40 50
50 60 70 80 90 100
pF1KB0 LRKFPAGKVPAFE-GDDGFCVFESNAIAYYVSNEELRG-STPEAAAQVVQWVSFADSDIV
:: ..::.: : :. :. ..:.: . : : . .::. : ::::.::....
NP_006 ---FPPPRLPALEQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELI
60 70 80 90 100
110 120 130 140 150 160
pF1KB0 PPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCT
: : ..:.:: .. . : . . . : :. :. .:. .:.:.:: ::::...: .
NP_006 PAACGATLPALG-LRSSAQDPQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB0 LLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQ--
:: .. ::.: :. . :..:::.::. ::.:::::::: : .. . :.
NP_006 LLLPFRYVLDPPARRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPEAPAL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB0 PKKDTP-RKEKGSREEKQKPQAERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLP
:: . .:: .::. .: : ..: ... : : :. . :. .:
NP_006 PKTAAQLKKEAKKREKLEKFQQKQKIQQQQ--PPPGEKKPKPEKREKRDPGVITYDLPTP
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB0 KSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYSEYRFPEELTQTFMSCNLITG
NP_006 PGEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPN
290 300 310 320 330 340
>>XP_005249419 (OMIM: 192150) PREDICTED: valine--tRNA li (1265 aa)
initn: 335 init1: 246 opt: 429 Z-score: 392.5 bits: 83.3 E(85289): 4e-15
Smith-Waterman score: 449; 33.7% identity (58.9% similar) in 309 aa overlap (5-286:3-300)
10 20 30 40
pF1KB0 MAAGTLYT--YPENWRAFKALIAAQYS---------GAQVRVLSAPPHFHFGQTNRTPEF
:::. .:. . ...:::::.:. ::. :. :: :.:::
XP_005 MSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPP-----PTSRTP--
10 20 30 40 50
50 60 70 80 90 100
pF1KB0 LRKFPAGKVPAFE-GDDGFCVFESNAIAYYVSNEELRG-STPEAAAQVVQWVSFADSDIV
:: ..::.: : :. :. ..:.: . : : . .::. : ::::.::....
XP_005 ---FPPPRLPALEQGPGGLWVWGATAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELI
60 70 80 90 100
110 120 130 140 150 160
pF1KB0 PPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCT
: : ..:.:: .. . : . . . : :. :. .:. .:.:.:: ::::...: .
XP_005 PAACGATLPALG-LRSSAQDPQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB0 LLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQF------DAKKF
:: .. ::.: :. . :..:::.::. ::.:::::::: : . .: .
XP_005 LLLPFRYVLDPPARRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPLSHQPGPEAPAL
170 180 190 200 210 220
230 240 250 260 270
pF1KB0 AET--QPKKDTPRKEKGSR-EEKQKPQAERKEEKKAAAPAPE--EEMDE--CEQALAAEP
.: : ::.. ..:: . ..::: : .. . : :: :. : : . :
XP_005 PKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEQKKPKPEKREKRDPGVITYDLPTPP
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB0 -KAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYSEYRFPEELT
. :: . .: :
XP_005 GEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNV
290 300 310 320 330 340
437 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:35:09 2016 done: Sat Nov 5 17:35:11 2016
Total Scan time: 7.660 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]