FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0974, 437 aa 1>>>pF1KB0974 437 - 437 aa - 437 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1737+/-0.000311; mu= 14.3067+/- 0.019 mean_var=102.3210+/-19.884, 0's: 0 Z-trim(119.3): 46 B-trim: 73 in 1/52 Lambda= 0.126792 statistics sampled from 33112 (33159) to 33112 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.389), width: 16 Scan time: 10.390 The best scores are: opt bits E(85289) NP_065139 (OMIM: 162860) CD177 antigen precursor [ ( 437) 3056 569.3 7e-162 XP_016882510 (OMIM: 162860) PREDICTED: CD177 antig ( 467) 2844 530.5 3.5e-150 XP_016882511 (OMIM: 162860) PREDICTED: CD177 antig ( 412) 2830 527.9 1.9e-149 NP_001123483 (OMIM: 612665) testis-expressed seque ( 249) 430 88.7 1.8e-17 NP_113639 (OMIM: 612665) testis-expressed sequence ( 267) 430 88.8 1.9e-17 XP_005259360 (OMIM: 612665) PREDICTED: testis-expr ( 305) 430 88.8 2.1e-17 NP_055215 (OMIM: 609484) ly6/PLAUR domain-containi ( 346) 173 41.8 0.0033 >>NP_065139 (OMIM: 162860) CD177 antigen precursor [Homo (437 aa) initn: 3056 init1: 3056 opt: 3056 Z-score: 3027.3 bits: 569.3 E(85289): 7e-162 Smith-Waterman score: 3056; 99.1% identity (99.5% similar) in 437 aa overlap (1-437:1-437) 10 20 30 40 50 60 pF1KB0 MSAVLLLALLGFILPLPGVQALLCQFGTVQHVWKVSDLPRQWTPKNTSCDSGLGCQDTLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MSAVLLLALLGFILPLPGVQALLCQFGTVQHVWKVSDLPRQWTPKNTSCDSGLGCQDTLM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LIESGPQVSLVLSKGCTEAKDQEPRVTEHRMGPGLSLISYTFVCRQEDFCNNLVNSLPLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LIESGPQVSLVLSKGCTEAKDQEPRVTEHRMGPGLSLISYTFVCRQEDFCNNLVNSLPLW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 APQPPADPGSLRCPVCLSMEGCLEGTTEEICPKGTTHCYDGLLRLRGGGIFSNLRVQGCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 APQPPADPGSLRCPVCLSMEGCLEGTTEEICPKGTTHCYDGLLRLRGGGIFSNLRVQGCM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PQPGCNLLNGTQEIGPVGMTENCNRKDFLTCHRGTTIMTHGNLAQEPTDWTTSNTEMCEV ::: :::::::::::::::::::. ::::::::::::::::::::::::::::::::::: NP_065 PQPVCNLLNGTQEIGPVGMTENCDMKDFLTCHRGTTIMTHGNLAQEPTDWTTSNTEMCEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 GQVCQETLLLIDVGLTSTLVGTKGCSTVGAQNSQKTTIHSAPPGVLVASYTHFCSSDLCN ::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GQVCQETLLLLDVGLTSTLVGTKGCSTVGAQNSQKTTIHSAPPGVLVASYTHFCSSDLCN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 SASSSSVLLNSLPPQAAPVPGDRQCPTCVQPLGTCSSGSPRMTCPRGATHCYDGYIHLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SASSSSVLLNSLPPQAAPVPGDRQCPTCVQPLGTCSSGSPRMTCPRGATHCYDGYIHLSG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 GGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSAREKRDVQPPASQHEGGGAEGLESLTWGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSAREKRDVQPPASQHEGGGAEGLESLTWGV 370 380 390 400 410 420 430 pF1KB0 GLALAPALWWGVVCPSC ::::::::::::::::: NP_065 GLALAPALWWGVVCPSC 430 >>XP_016882510 (OMIM: 162860) PREDICTED: CD177 antigen i (467 aa) initn: 3146 init1: 2841 opt: 2844 Z-score: 2817.3 bits: 530.5 E(85289): 3.5e-150 Smith-Waterman score: 2844; 95.8% identity (97.4% similar) in 427 aa overlap (1-427:1-426) 10 20 30 40 50 60 pF1KB0 MSAVLLLALLGFILPLPGVQALLCQFGTVQHVWKVSDLPRQWTPKNTSCDSGLGCQDTLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSAVLLLALLGFILPLPGVQALLCQFGTVQHVWKVSDLPRQWTPKNTSCDSGLGCQDTLM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LIESGPQVSLVLSKGCTEAKDQEPRVTEHRMGPGLSLISYTFVCRQEDFCNNLVNSLPLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIESGPQVSLVLSKGCTEAKDQEPRVTEHRMGPGLSLISYTFVCRQEDFCNNLVNSLPLW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 APQPPADPGSLRCPVCLSMEGCLEGTTEEICPKGTTHCYDGLLRLRGGGIFSNLRVQGCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APQPPADPGSLRCPVCLSMEGCLEGTTEEICPKGTTHCYDGLLRLRGGGIFSNLRVQGCM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PQPGCNLLNGTQEIGPVGMTENCNRKDFLTCHRGTTIMTHGNLAQEPTDWTTSNTEMCEV ::: :::::::::::::::::::. ::::::::::::::::::::::::::::::::::: XP_016 PQPVCNLLNGTQEIGPVGMTENCDMKDFLTCHRGTTIMTHGNLAQEPTDWTTSNTEMCEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 GQVCQETLLLIDVGLTSTLVGTKGCSTVGAQNSQKTTIHSAPPGVLVASYTHFCSSDLCN ::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQVCQETLLLLDVGLTSTLVGTKGCSTVGAQNSQKTTIHSAPPGVLVASYTHFCSSDLCN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 SASSSSVLLNSLPPQAAPVPGDRQCPTCVQPLGTCSSGSPRMTCPRGATHCYDGYIHLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SASSSSVLLNSLPPQAAPVPGDRQCPTCVQPLGTCSSGSPRMTCPRGATHCYDGYIHLSG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 GGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSAREKRDVQPPASQHEGGGAEGLESLTWGV :::::::::::::::::::::::::::::::::::::::::::::::: : . . . .: XP_016 GGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSAREKRDVQPPASQHEGGPPE-VGTKAAAV 370 380 390 400 410 430 pF1KB0 GLALAPALWWGVVCPSC . ::: XP_016 HFCWAPAHREDPSISLVCTFLLCMRSQGFPGAHRCGRGRGRRTGAMGA 420 430 440 450 460 >>XP_016882511 (OMIM: 162860) PREDICTED: CD177 antigen i (412 aa) initn: 2830 init1: 2830 opt: 2830 Z-score: 2804.2 bits: 527.9 E(85289): 1.9e-149 Smith-Waterman score: 2830; 99.0% identity (99.5% similar) in 407 aa overlap (1-407:1-407) 10 20 30 40 50 60 pF1KB0 MSAVLLLALLGFILPLPGVQALLCQFGTVQHVWKVSDLPRQWTPKNTSCDSGLGCQDTLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSAVLLLALLGFILPLPGVQALLCQFGTVQHVWKVSDLPRQWTPKNTSCDSGLGCQDTLM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LIESGPQVSLVLSKGCTEAKDQEPRVTEHRMGPGLSLISYTFVCRQEDFCNNLVNSLPLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIESGPQVSLVLSKGCTEAKDQEPRVTEHRMGPGLSLISYTFVCRQEDFCNNLVNSLPLW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 APQPPADPGSLRCPVCLSMEGCLEGTTEEICPKGTTHCYDGLLRLRGGGIFSNLRVQGCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APQPPADPGSLRCPVCLSMEGCLEGTTEEICPKGTTHCYDGLLRLRGGGIFSNLRVQGCM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 PQPGCNLLNGTQEIGPVGMTENCNRKDFLTCHRGTTIMTHGNLAQEPTDWTTSNTEMCEV ::: :::::::::::::::::::. ::::::::::::::::::::::::::::::::::: XP_016 PQPVCNLLNGTQEIGPVGMTENCDMKDFLTCHRGTTIMTHGNLAQEPTDWTTSNTEMCEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 GQVCQETLLLIDVGLTSTLVGTKGCSTVGAQNSQKTTIHSAPPGVLVASYTHFCSSDLCN ::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQVCQETLLLLDVGLTSTLVGTKGCSTVGAQNSQKTTIHSAPPGVLVASYTHFCSSDLCN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 SASSSSVLLNSLPPQAAPVPGDRQCPTCVQPLGTCSSGSPRMTCPRGATHCYDGYIHLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SASSSSVLLNSLPPQAAPVPGDRQCPTCVQPLGTCSSGSPRMTCPRGATHCYDGYIHLSG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 GGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSAREKRDVQPPASQHEGGGAEGLESLTWGV ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSAREKRDVQPPASQHEGVEVPH 370 380 390 400 410 430 pF1KB0 GLALAPALWWGVVCPSC >>NP_001123483 (OMIM: 612665) testis-expressed sequence (249 aa) initn: 411 init1: 199 opt: 430 Z-score: 434.6 bits: 88.7 E(85289): 1.8e-17 Smith-Waterman score: 464; 33.9% identity (66.1% similar) in 224 aa overlap (209-428:26-241) 180 190 200 210 220 230 pF1KB0 CMPQPGCNLLNGTQEIGPVGMTENCNRKDFLTCHRGTTIMTHGNLAQEPTDWTTSNTEMC : :..: .. .... :. .::: ..: : NP_001 MGTPRIQHLLILLVLGASLLTSGLELYCQKGLSMTVEADPANM-FNWTTEEVETC 10 20 30 40 50 240 250 260 270 280 290 pF1KB0 EVGQVCQETLLLIDVGLTSTLVGTKGCSTVGAQNSQKTTIHSAPPGVLVASYTHFCSSDL . : .::::.:.: .: .....:::: : ... . ::.:::..:.::...: ... NP_001 DKGALCQETILIIKAGTETAILATKGCIPEG-EEAITIVQHSSPPGLIVTSYSNYCEDSF 60 70 80 90 100 110 300 310 320 330 340 350 pF1KB0 CNSASSSSVLLNSLPPQAAPVPGDRQCPTCVQPLGTCSSGSPRMTCPRGATHCYDGYIHL ::. .: : . . :. : .::::: :::: : .: . :: :.:.::.: ... NP_001 CNDKDSLSQFWEFSETTASTVSTTLHCPTCVA-LGTCFS-APSLPCPNGTTRCYQGKLEI 120 130 140 150 160 170 360 370 380 390 400 410 pF1KB0 SGGGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSARE----KRDVQPPASQHEGGGAEGLE .:::. ... ..::.:. . :.. .: . .:: . .:: ... :: : NP_001 TGGGIESSVEVKGCTAMIGCRLMSGILAVGPMFVREACPHQLLTQPRKTEN---GATCLP 180 190 200 210 220 420 430 pF1KB0 SLTWGVGLALAPALWWGVVCPSC .::. : : : : NP_001 IPVWGLQLLL-PLLLPSFIHFS 230 240 >>NP_113639 (OMIM: 612665) testis-expressed sequence 101 (267 aa) initn: 411 init1: 199 opt: 430 Z-score: 434.2 bits: 88.8 E(85289): 1.9e-17 Smith-Waterman score: 464; 33.9% identity (66.1% similar) in 224 aa overlap (209-428:44-259) 180 190 200 210 220 230 pF1KB0 CMPQPGCNLLNGTQEIGPVGMTENCNRKDFLTCHRGTTIMTHGNLAQEPTDWTTSNTEMC : :..: .. .... :. .::: ..: : NP_113 SPEEAMGTPRIQHLLILLVLGASLLTSGLELYCQKGLSMTVEADPANM-FNWTTEEVETC 20 30 40 50 60 70 240 250 260 270 280 290 pF1KB0 EVGQVCQETLLLIDVGLTSTLVGTKGCSTVGAQNSQKTTIHSAPPGVLVASYTHFCSSDL . : .::::.:.: .: .....:::: : ... . ::.:::..:.::...: ... NP_113 DKGALCQETILIIKAGTETAILATKGCIPEG-EEAITIVQHSSPPGLIVTSYSNYCEDSF 80 90 100 110 120 130 300 310 320 330 340 350 pF1KB0 CNSASSSSVLLNSLPPQAAPVPGDRQCPTCVQPLGTCSSGSPRMTCPRGATHCYDGYIHL ::. .: : . . :. : .::::: :::: : .: . :: :.:.::.: ... NP_113 CNDKDSLSQFWEFSETTASTVSTTLHCPTCVA-LGTCFS-APSLPCPNGTTRCYQGKLEI 140 150 160 170 180 360 370 380 390 400 410 pF1KB0 SGGGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSARE----KRDVQPPASQHEGGGAEGLE .:::. ... ..::.:. . :.. .: . .:: . .:: ... :: : NP_113 TGGGIESSVEVKGCTAMIGCRLMSGILAVGPMFVREACPHQLLTQPRKTEN---GATCLP 190 200 210 220 230 240 420 430 pF1KB0 SLTWGVGLALAPALWWGVVCPSC .::. : : : : NP_113 IPVWGLQLLL-PLLLPSFIHFS 250 260 >>XP_005259360 (OMIM: 612665) PREDICTED: testis-expresse (305 aa) initn: 432 init1: 199 opt: 430 Z-score: 433.4 bits: 88.8 E(85289): 2.1e-17 Smith-Waterman score: 464; 33.9% identity (66.1% similar) in 224 aa overlap (209-428:82-297) 180 190 200 210 220 230 pF1KB0 CMPQPGCNLLNGTQEIGPVGMTENCNRKDFLTCHRGTTIMTHGNLAQEPTDWTTSNTEMC : :..: .. .... :. .::: ..: : XP_005 SPEEAMGTPRIQHLLILLVLGASLLTSGLELYCQKGLSMTVEADPANM-FNWTTEEVETC 60 70 80 90 100 110 240 250 260 270 280 290 pF1KB0 EVGQVCQETLLLIDVGLTSTLVGTKGCSTVGAQNSQKTTIHSAPPGVLVASYTHFCSSDL . : .::::.:.: .: .....:::: : ... . ::.:::..:.::...: ... XP_005 DKGALCQETILIIKAGTETAILATKGCIPEG-EEAITIVQHSSPPGLIVTSYSNYCEDSF 120 130 140 150 160 300 310 320 330 340 350 pF1KB0 CNSASSSSVLLNSLPPQAAPVPGDRQCPTCVQPLGTCSSGSPRMTCPRGATHCYDGYIHL ::. .: : . . :. : .::::: :::: : .: . :: :.:.::.: ... XP_005 CNDKDSLSQFWEFSETTASTVSTTLHCPTCVA-LGTCFS-APSLPCPNGTTRCYQGKLEI 170 180 190 200 210 220 360 370 380 390 400 410 pF1KB0 SGGGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSARE----KRDVQPPASQHEGGGAEGLE .:::. ... ..::.:. . :.. .: . .:: . .:: ... :: : XP_005 TGGGIESSVEVKGCTAMIGCRLMSGILAVGPMFVREACPHQLLTQPRKTEN---GATCLP 230 240 250 260 270 280 420 430 pF1KB0 SLTWGVGLALAPALWWGVVCPSC .::. : : : : XP_005 IPVWGLQLLL-PLLLPSFIHFS 290 300 >>NP_055215 (OMIM: 609484) ly6/PLAUR domain-containing p (346 aa) initn: 97 init1: 76 opt: 173 Z-score: 178.6 bits: 41.8 E(85289): 0.0033 Smith-Waterman score: 173; 23.3% identity (56.4% similar) in 172 aa overlap (214-373:27-194) 190 200 210 220 230 240 pF1KB0 GCNLLNGTQEIGPVGMTENCNRKDFLTCHRGTTIMTHGNLAQEPTDWTTSN---TEMCEV :. . . .:. : . : : : NP_055 MDPARKAGAQAMIWTAGWLLLLLLRGGAQALECYSCVQKADDGCSPNKMKTVKCAP 10 20 30 40 50 250 260 270 280 290 pF1KB0 G-QVCQETLLLIDVGLTSTLVGTKGC-STVGAQNSQKTTIHSAPPGVLVASYTHFCSSDL : .:: :.. ... . ....:: : . ..:.. .: :.:. . :..: NP_055 GVDVCTEAVGAVETIHGQFSLAVRGCGSGLPGKNDRGLDLH----GLLAFIQLQQCAQDR 60 70 80 90 100 110 300 310 320 330 340 350 pF1KB0 CNSASS-SSVLLNSLPPQAAPVPGDRQCPTCVQ-PLGTCSSGSPRM-TCPRGATH----C ::. . .: :. ..: :. .: .:: .:.. :: . .: .. : : NP_055 CNAKLNLTSRALDPAGNESAYPPNGVECYSCVGLSREACQGTSPPVVSCYNASDHVYKGC 120 130 140 150 160 170 360 370 380 390 400 410 pF1KB0 YDGYIHLSGGGLSTKMSIQGCVAQPSSFLLNHTRQIGIFSAREKRDVQPPASQHEGGGAE .:: . :......... ..::: NP_055 FDGNVTLTAANVTVSLPVRGCVQDEFCTRDGVTGPGFTLSGSCCQGSRCNSDLRNKTYFS 180 190 200 210 220 230 437 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:36:27 2016 done: Sat Nov 5 17:36:29 2016 Total Scan time: 10.390 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]