FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0977, 188 aa 1>>>pF1KB0977 188 - 188 aa - 188 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0332+/-0.000337; mu= 11.1438+/- 0.021 mean_var=106.4081+/-21.152, 0's: 0 Z-trim(117.9): 50 B-trim: 1583 in 2/54 Lambda= 0.124333 statistics sampled from 30352 (30403) to 30352 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.356), width: 16 Scan time: 5.850 The best scores are: opt bits E(85289) XP_011542251 (OMIM: 300327) PREDICTED: protein SSX ( 188) 1282 239.7 2.1e-63 XP_016885247 (OMIM: 300327) PREDICTED: protein SSX ( 188) 1282 239.7 2.1e-63 NP_783729 (OMIM: 300327) protein SSX5 isoform b [H ( 188) 1282 239.7 2.1e-63 NP_066295 (OMIM: 300327) protein SSX5 isoform a [H ( 229) 1130 212.5 3.9e-55 NP_066294 (OMIM: 300325) protein SSX3 [Homo sapien ( 188) 1102 207.4 1.1e-53 NP_783629 (OMIM: 300192,300813) protein SSX2 isofo ( 188) 1093 205.8 3.3e-53 NP_775494 (OMIM: 300542) protein SSX7 [Homo sapien ( 188) 1067 201.2 8.4e-52 XP_016885248 (OMIM: 300326) PREDICTED: protein SSX ( 188) 1000 189.1 3.5e-48 NP_005627 (OMIM: 300326) protein SSX4 isoform a [H ( 188) 1000 189.1 3.5e-48 NP_005626 (OMIM: 300813,312820) protein SSX1 [Homo ( 188) 991 187.5 1.1e-47 NP_001265620 (OMIM: 300813,312820) protein SSX1 [H ( 188) 991 187.5 1.1e-47 XP_011542187 (OMIM: 300325) PREDICTED: protein SSX ( 170) 891 169.6 2.5e-42 NP_001265626 (OMIM: 300192,300813) protein SSX2 is ( 214) 887 168.9 4.9e-42 NP_003138 (OMIM: 300192,300813) protein SSX2 isofo ( 223) 887 168.9 5e-42 XP_016884919 (OMIM: 300542) PREDICTED: protein SSX ( 223) 853 162.8 3.4e-40 XP_016884920 (OMIM: 300542) PREDICTED: protein SSX ( 129) 614 119.8 1.8e-27 NP_783856 (OMIM: 300326) protein SSX4 isoform b [H ( 153) 584 114.4 8.7e-26 XP_011521131 (OMIM: 609759) PREDICTED: probable hi ( 377) 181 42.5 0.00098 NP_001091643 (OMIM: 609759) probable histone-lysin ( 492) 181 42.6 0.0012 XP_005256331 (OMIM: 609759) PREDICTED: probable hi ( 492) 181 42.6 0.0012 NP_001297143 (OMIM: 609760) histone-lysine N-methy ( 894) 183 43.2 0.0015 NP_064612 (OMIM: 609760) histone-lysine N-methyltr ( 894) 183 43.2 0.0015 XP_011521133 (OMIM: 609759) PREDICTED: probable hi ( 172) 167 39.7 0.0031 >>XP_011542251 (OMIM: 300327) PREDICTED: protein SSX5 is (188 aa) initn: 1282 init1: 1282 opt: 1282 Z-score: 1259.4 bits: 239.7 E(85289): 2.1e-63 Smith-Waterman score: 1282; 99.5% identity (100.0% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB0 MNGDDAFVRRPRVGSQIPQKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_011 MNGDDAFVRRPRVGSQIPEKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI 130 140 150 160 170 180 pF1KB0 SDPQEDDE :::::::: XP_011 SDPQEDDE >>XP_016885247 (OMIM: 300327) PREDICTED: protein SSX5 is (188 aa) initn: 1282 init1: 1282 opt: 1282 Z-score: 1259.4 bits: 239.7 E(85289): 2.1e-63 Smith-Waterman score: 1282; 99.5% identity (100.0% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB0 MNGDDAFVRRPRVGSQIPQKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_016 MNGDDAFVRRPRVGSQIPEKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI 130 140 150 160 170 180 pF1KB0 SDPQEDDE :::::::: XP_016 SDPQEDDE >>NP_783729 (OMIM: 300327) protein SSX5 isoform b [Homo (188 aa) initn: 1282 init1: 1282 opt: 1282 Z-score: 1259.4 bits: 239.7 E(85289): 2.1e-63 Smith-Waterman score: 1282; 99.5% identity (100.0% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB0 MNGDDAFVRRPRVGSQIPQKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: NP_783 MNGDDAFVRRPRVGSQIPEKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_783 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_783 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI 130 140 150 160 170 180 pF1KB0 SDPQEDDE :::::::: NP_783 SDPQEDDE >>NP_066295 (OMIM: 300327) protein SSX5 isoform a [Homo (229 aa) initn: 1130 init1: 1130 opt: 1130 Z-score: 1110.9 bits: 212.5 E(85289): 3.9e-55 Smith-Waterman score: 1130; 99.4% identity (100.0% similar) in 166 aa overlap (23-188:64-229) 10 20 30 40 50 pF1KB0 MNGDDAFVRRPRVGSQIPQKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMK .::::::::::::::::::::::::::::: NP_066 IHLVNLSPFWKVGREPASSIKALLCGRGEARAFDDIAKYFSEKEWEKMKASEKIIYVYMK 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB0 RKYEAMTKLGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 RKYEAMTKLGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKIT 100 110 120 130 140 150 120 130 140 150 160 170 pF1KB0 PEKPAEEGNDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 PEKPAEEGNDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERK 160 170 180 190 200 210 180 pF1KB0 QLVIYEEISDPQEDDE :::::::::::::::: NP_066 QLVIYEEISDPQEDDE 220 >>NP_066294 (OMIM: 300325) protein SSX3 [Homo sapiens] (188 aa) initn: 1102 init1: 1102 opt: 1102 Z-score: 1084.9 bits: 207.4 E(85289): 1.1e-53 Smith-Waterman score: 1102; 84.0% identity (94.1% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB0 MNGDDAFVRRPRVGSQIPQKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK :::::.:.::: ::.:::.:.::::::::::::..::::::.::::.::::::::::::: NP_066 MNGDDTFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKVSEKIVYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG ::::: :: :::::::.:::::::::::::::::..::::::::::::::: :.:::::: NP_066 LGFKAILPSFMRNKRVTDFQGNDFDNDPNRGNQVQRPQMTFGRLQGIFPKIMPKKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI : :: :::::::::.:::: : :: .::::.: ::::::.::::::.:::::::::::: NP_066 NVSKEVPEASGPQNDGKQLCPPGKPTTSEKINMISGPKRGEHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB0 SDPQEDDE :::.:::: NP_066 SDPEEDDE >>NP_783629 (OMIM: 300192,300813) protein SSX2 isoform b (188 aa) initn: 1093 init1: 1093 opt: 1093 Z-score: 1076.2 bits: 205.8 E(85289): 3.3e-53 Smith-Waterman score: 1093; 83.5% identity (94.7% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB0 MNGDDAFVRRPRVGSQIPQKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK :::::::.::: ::.:::.:.::::::::::::..:::::::::::.::::::::::::: NP_783 MNGDDAFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKASEKIFYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG ::::::::::: :::. ::::::.:::::::::::.::::::::::: ::: :.:::::: NP_783 LGFKATLPPFMCNKRAEDFQGNDLDNDPNRGNQVERPQMTFGRLQGISPKIMPKKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI :::. :::::::::.::.: : :: .::::... ::::::.::::::.:::::::::::: NP_783 NDSEEVPEASGPQNDGKELCPPGKPTTSEKIHERSGPKRGEHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB0 SDPQEDDE :::.:::: NP_783 SDPEEDDE >>NP_775494 (OMIM: 300542) protein SSX7 [Homo sapiens] (188 aa) initn: 1067 init1: 1067 opt: 1067 Z-score: 1051.0 bits: 201.2 E(85289): 8.4e-52 Smith-Waterman score: 1067; 82.4% identity (93.6% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB0 MNGDDAFVRRPRVGSQIPQKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK :::::::.::::.:.:::.:.::.:::::::::.:::::::. ::: ::::::::::::: NP_775 MNGDDAFARRPRAGAQIPEKIQKSFDDIAKYFSKKEWEKMKSLEKISYVYMKRKYEAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG :::::::::::.: ..:.:::::::: :.:::::.::::: ::: ::::: :.:::::: NP_775 LGFKATLPPFMHNTGATDLQGNDFDNDRNQGNQVERPQMTFCRLQRIFPKIMPKKPAEEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI ::::::::::: ::.::.: : :: .::::.::::::::::::::::.:::::::::::: NP_775 NDSKGVPEASGSQNDGKHLCPPGKPSTSEKINKTSGPKRGKHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB0 SDPQEDDE :::.:::: NP_775 SDPEEDDE >>XP_016885248 (OMIM: 300326) PREDICTED: protein SSX4 is (188 aa) initn: 1000 init1: 1000 opt: 1000 Z-score: 986.0 bits: 189.1 E(85289): 3.5e-48 Smith-Waterman score: 1000; 77.7% identity (90.4% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB0 MNGDDAFVRRPRVGSQIPQKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK :::::::.:::: .:: .:..:::::::::::.:::::::.::::.::::: .::.::: XP_016 MNGDDAFARRPRDDAQISEKLRKAFDDIAKYFSKKEWEKMKSSEKIVYVYMKLNYEVMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG ::::.:::::::.::.:::.:::: :: :. ::::.:::::: :: ::::: :.::::: XP_016 LGFKVTLPPFMRSKRAADFHGNDFGNDRNHRNQVERPQMTFGSLQRIFPKIMPKKPAEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI : : :::::::::.:::: : :. .: ::.::::::::::::::::.:::::::.:::: XP_016 NGLKEVPEASGPQNDGKQLCPPGNPSTLEKINKTSGPKRGKHAWTHRLRERKQLVVYEEI 130 140 150 160 170 180 pF1KB0 SDPQEDDE :::.:::: XP_016 SDPEEDDE >>NP_005627 (OMIM: 300326) protein SSX4 isoform a [Homo (188 aa) initn: 1000 init1: 1000 opt: 1000 Z-score: 986.0 bits: 189.1 E(85289): 3.5e-48 Smith-Waterman score: 1000; 77.7% identity (90.4% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB0 MNGDDAFVRRPRVGSQIPQKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK :::::::.:::: .:: .:..:::::::::::.:::::::.::::.::::: .::.::: NP_005 MNGDDAFARRPRDDAQISEKLRKAFDDIAKYFSKKEWEKMKSSEKIVYVYMKLNYEVMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG ::::.:::::::.::.:::.:::: :: :. ::::.:::::: :: ::::: :.::::: NP_005 LGFKVTLPPFMRSKRAADFHGNDFGNDRNHRNQVERPQMTFGSLQRIFPKIMPKKPAEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI : : :::::::::.:::: : :. .: ::.::::::::::::::::.:::::::.:::: NP_005 NGLKEVPEASGPQNDGKQLCPPGNPSTLEKINKTSGPKRGKHAWTHRLRERKQLVVYEEI 130 140 150 160 170 180 pF1KB0 SDPQEDDE :::.:::: NP_005 SDPEEDDE >>NP_005626 (OMIM: 300813,312820) protein SSX1 [Homo sap (188 aa) initn: 991 init1: 991 opt: 991 Z-score: 977.3 bits: 187.5 E(85289): 1.1e-47 Smith-Waterman score: 991; 76.6% identity (89.4% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB0 MNGDDAFVRRPRVGSQIPQKMQKAFDDIAKYFSEKEWEKMKASEKIIYVYMKRKYEAMTK :::::.:..::: .. .: .::::::: :::.:::.::: :::: ::::::.:.:::: NP_005 MNGDDTFAKRPRDDAKASEKRSKAFDDIATYFSKKEWKKMKYSEKISYVYMKRNYKAMTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 LGFKATLPPFMRNKRVADFQGNDFDNDPNRGNQVEHPQMTFGRLQGIFPKITPEKPAEEG ::::.:::::: ::...:::::::::: :: ::::::::::::. :.::: :.::::. NP_005 LGFKVTLPPFMCNKQATDFQGNDFDNDHNRRIQVEHPQMTFGRLHRIIPKIMPKKPAEDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NDSKGVPEASGPQNNGKQLRPSGKLNTSEKVNKTSGPKRGKHAWTHRVRERKQLVIYEEI :::::: :::::::.::::.: :: : :::.:: :::::::::::::.:::::::::::: NP_005 NDSKGVSEASGPQNDGKQLHPPGKANISEKINKRSGPKRGKHAWTHRLRERKQLVIYEEI 130 140 150 160 170 180 pF1KB0 SDPQEDDE :::.:::: NP_005 SDPEEDDE 188 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:38:10 2016 done: Sat Nov 5 17:38:11 2016 Total Scan time: 5.850 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]