FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0980, 450 aa 1>>>pF1KB0980 450 - 450 aa - 450 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1217+/-0.000854; mu= 4.9983+/- 0.052 mean_var=153.9259+/-31.643, 0's: 0 Z-trim(112.3): 48 B-trim: 7 in 1/50 Lambda= 0.103376 statistics sampled from 13048 (13091) to 13048 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.402), width: 16 Scan time: 2.560 The best scores are: opt bits E(32554) CCDS46398.1 PAX8 gene_id:7849|Hs108|chr2 ( 450) 3045 465.8 4.1e-131 CCDS46399.1 PAX8 gene_id:7849|Hs108|chr2 ( 398) 2050 317.3 1.7e-86 CCDS42736.1 PAX8 gene_id:7849|Hs108|chr2 ( 321) 1780 277.0 1.9e-74 CCDS42735.1 PAX8 gene_id:7849|Hs108|chr2 ( 287) 1777 276.5 2.4e-74 CCDS41561.1 PAX2 gene_id:5076|Hs108|chr10 ( 394) 1287 203.5 3.1e-52 CCDS7499.1 PAX2 gene_id:5076|Hs108|chr10 ( 396) 1277 202.1 8.7e-52 CCDS65047.1 PAX5 gene_id:5079|Hs108|chr9 ( 357) 1151 183.2 3.6e-46 CCDS65046.1 PAX5 gene_id:5079|Hs108|chr9 ( 328) 1141 181.7 9.5e-46 CCDS65048.1 PAX5 gene_id:5079|Hs108|chr9 ( 362) 1141 181.7 1e-45 CCDS6607.1 PAX5 gene_id:5079|Hs108|chr9 ( 391) 1138 181.3 1.5e-45 CCDS65045.1 PAX5 gene_id:5079|Hs108|chr9 ( 324) 1108 176.8 2.8e-44 CCDS65044.1 PAX5 gene_id:5079|Hs108|chr9 ( 295) 1081 172.8 4.3e-43 CCDS65042.1 PAX5 gene_id:5079|Hs108|chr9 ( 319) 876 142.2 7.3e-34 CCDS65043.1 PAX5 gene_id:5079|Hs108|chr9 ( 348) 876 142.2 7.9e-34 CCDS31451.1 PAX6 gene_id:5080|Hs108|chr11 ( 422) 791 129.6 6.1e-30 CCDS46522.1 PAX3 gene_id:5077|Hs108|chr2 ( 483) 680 113.1 6.5e-25 CCDS74709.1 PAX1 gene_id:5075|Hs108|chr20 ( 457) 668 111.3 2.2e-24 CCDS42826.1 PAX3 gene_id:5077|Hs108|chr2 ( 479) 668 111.3 2.2e-24 CCDS42825.1 PAX3 gene_id:5077|Hs108|chr2 ( 484) 668 111.3 2.3e-24 CCDS9662.1 PAX9 gene_id:5083|Hs108|chr14 ( 341) 665 110.7 2.3e-24 CCDS2448.1 PAX3 gene_id:5077|Hs108|chr2 ( 505) 668 111.3 2.3e-24 CCDS13146.2 PAX1 gene_id:5075|Hs108|chr20 ( 534) 668 111.3 2.5e-24 CCDS2450.1 PAX3 gene_id:5077|Hs108|chr2 ( 403) 642 107.4 2.9e-23 CCDS2449.1 PAX3 gene_id:5077|Hs108|chr2 ( 407) 642 107.4 2.9e-23 CCDS2451.1 PAX3 gene_id:5077|Hs108|chr2 ( 206) 636 106.3 3e-23 CCDS46523.1 PAX3 gene_id:5077|Hs108|chr2 ( 215) 636 106.3 3.1e-23 CCDS44075.1 PAX7 gene_id:5081|Hs108|chr1 ( 518) 635 106.4 7.3e-23 CCDS44074.1 PAX7 gene_id:5081|Hs108|chr1 ( 505) 627 105.2 1.6e-22 CCDS186.1 PAX7 gene_id:5081|Hs108|chr1 ( 520) 627 105.2 1.7e-22 CCDS5797.1 PAX4 gene_id:5078|Hs108|chr7 ( 343) 558 94.8 1.5e-19 CCDS31452.1 PAX6 gene_id:5080|Hs108|chr11 ( 436) 558 94.8 1.8e-19 CCDS65039.1 PAX5 gene_id:5079|Hs108|chr9 ( 220) 529 90.4 2e-18 CCDS65040.1 PAX5 gene_id:5079|Hs108|chr9 ( 283) 415 73.4 3.3e-13 CCDS65041.1 PAX5 gene_id:5079|Hs108|chr9 ( 291) 391 69.8 4e-12 >>CCDS46398.1 PAX8 gene_id:7849|Hs108|chr2 (450 aa) initn: 3045 init1: 3045 opt: 3045 Z-score: 2467.4 bits: 465.8 E(32554): 4.1e-131 Smith-Waterman score: 3045; 100.0% identity (100.0% similar) in 450 aa overlap (1-450:1-450) 10 20 30 40 50 60 pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 PHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQAL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFP 370 380 390 400 410 420 430 440 450 pF1KB0 NSSLLSSPYYYSSTSRPSAPPTTATAFDHL :::::::::::::::::::::::::::::: CCDS46 NSSLLSSPYYYSSTSRPSAPPTTATAFDHL 430 440 450 >>CCDS46399.1 PAX8 gene_id:7849|Hs108|chr2 (398 aa) initn: 2091 init1: 2040 opt: 2050 Z-score: 1666.2 bits: 317.3 E(32554): 1.7e-86 Smith-Waterman score: 2052; 82.6% identity (86.5% similar) in 385 aa overlap (1-385:1-359) 10 20 30 40 50 60 pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 PHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQAL : :: : :.:.:.: : :: .: . :. .. CCDS46 P--PFWI--------CSKSAPGSRPSM-------------PFPMLPPCT---GSSRARPS 310 320 330 370 380 390 400 410 420 pF1KB0 LSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYSSYSEAWRFP .:.. :: : : : . ... CCDS46 SQGERWWGPRCPDTHPTSPPADRAAMPPLPSQAWWQEVNTLAMPMATPPTPPTARPGASP 340 350 360 370 380 390 >>CCDS42736.1 PAX8 gene_id:7849|Hs108|chr2 (321 aa) initn: 1829 init1: 1778 opt: 1780 Z-score: 1450.0 bits: 277.0 E(32554): 1.9e-74 Smith-Waterman score: 1780; 85.2% identity (89.6% similar) in 317 aa overlap (1-312:1-317) 10 20 30 40 50 60 pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 ERQHYPEAYASPSHTKGEQGLY---P-LPLLNSTLDDG-KATLTPSNTPLGRNLSTHQTY :::::::::::::::::::: : : . : . .:.. : . . . .. CCDS42 ERQHYPEAYASPSHTKGEQGERWWGPRCPDTHPTSPPADRAAMPPLPSQAWWQEVNTLAM 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB0 PVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQF :... : : : .: CCDS42 PMATPPTPPTARPGASPTPAC 310 320 >>CCDS42735.1 PAX8 gene_id:7849|Hs108|chr2 (287 aa) initn: 1796 init1: 1770 opt: 1777 Z-score: 1448.3 bits: 276.5 E(32554): 2.4e-74 Smith-Waterman score: 1777; 93.0% identity (94.7% similar) in 284 aa overlap (1-284:1-283) 10 20 30 40 50 60 pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTHQTYPVVAD ::::::::::::::::::: . : . .: : :. .: CCDS42 ERQHYPEAYASPSHTKGEQEVNTLAMPMAT-PPTPPTARPGASPTPAC 250 260 270 280 310 320 330 340 350 360 pF1KB0 PHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASVYGQFTGQAL >>CCDS41561.1 PAX2 gene_id:5076|Hs108|chr10 (394 aa) initn: 1509 init1: 870 opt: 1287 Z-score: 1051.3 bits: 203.5 E(32554): 3.1e-52 Smith-Waterman score: 1543; 55.5% identity (72.8% similar) in 449 aa overlap (2-448:9-392) 10 20 30 40 50 pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRV : .... ::::.:::::.::::::::.:::::::.::::::::::::::::: CCDS41 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 SHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLA ::::::::::::::::::.:::::::::::::::::.::..::::::::::::::::::: CCDS41 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 EGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQS ::.::::::::::::::::::::::::. : . ..: .::::..::.: : : .. CCDS41 EGICDNDTVPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASN 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 DSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHL : .:: :::::.::: . ...::: :.. ... . ::::. .. :::::.:.:.:..: CCDS41 DPVGS-YSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 EPLECPFERQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKATLTPSNTP-LGRNLST : :. ::: ::... . : :.::: : :: :. ::. :..:. :..: :: :.: CCDS41 EALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 HQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASV :::::: CCDS41 TQTYPVV----------------------------------------------------- 300 360 370 380 390 400 410 pF1KB0 YGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHTPYS .::.:.. ::::::::.: .::::: .:..:::: :::.::: :.: :. CCDS41 ----------TGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYT 310 320 330 340 350 420 430 440 450 pF1KB0 SYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDHL .:.::::: : .:::::::::.. : ::: ..:.:.: CCDS41 AYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAAAYDRH 360 370 380 390 >>CCDS7499.1 PAX2 gene_id:5076|Hs108|chr10 (396 aa) initn: 1308 init1: 870 opt: 1277 Z-score: 1043.2 bits: 202.1 E(32554): 8.7e-52 Smith-Waterman score: 1330; 51.2% identity (69.0% similar) in 445 aa overlap (2-443:9-386) 10 20 30 40 50 pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRV : .... ::::.:::::.::::::::.:::::::.::::::::::::::::: CCDS74 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 SHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLA ::::::::::::::::::.:::::::::::::::::.::..::::::::::::::::::: CCDS74 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 EGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQS ::.::::::::::::::::::::::::. : . ..: .::::..::.: : : .. CCDS74 EGICDNDTVPSVSSINRIIRTKVQQPFH-PTPDGAGTGVTAPGHTIVPSTASPPVSSASN 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 DSLGSTYSINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHL : .:: :::::.::: . ...::: :.. ... . ::::. .. :::::.:.:.:..: CCDS74 DPVGS-YSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 EPLECPFERQHYPEAYASPSHTKGEQG-LYPLPLLNSTLDDGKATLTPSNTP-LGRNLST : :. ::: ::... . : :.::: : :: :. ::. :..:. :..: :: :.: CCDS74 EALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 HQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHAASV :::::: CCDS74 TQTYPVV----------------------------------------------------- 300 360 370 380 390 400 410 pF1KB0 YGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYS-GNAYGHTPY .::.:.. ::::::::.: .::::: .:..:::: . . ... : CCDS74 ----------TGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPEAAVGPSSSLMSKPG 310 320 330 340 350 420 430 440 450 pF1KB0 SSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDHL . .:. . . ::: . :. ::. ::: CCDS74 RKLAEVPPCVQPTGASSPA--TRTATPSTRPTTRLGDSATPPY 360 370 380 390 >>CCDS65047.1 PAX5 gene_id:5079|Hs108|chr9 (357 aa) initn: 1216 init1: 864 opt: 1151 Z-score: 942.3 bits: 183.2 E(32554): 3.6e-46 Smith-Waterman score: 1191; 49.4% identity (64.5% similar) in 451 aa overlap (2-448:10-355) 10 20 30 40 50 pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLR :..: :.::::.:::::.::::::::.:::::::.:::::::::::::::: CCDS65 MDLEKNYPTPRTS-RTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 VSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLL :::::::::::::::::::.::::::::::::::::::::..:::::::::::::::::: CCDS65 VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 AEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQ :: :::::::::::::::::::::::: : :. . .:... ...:: : . CCDS65 AERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPA--------SSHSIVSTGSVTQVSSVS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 SDSLGSTYSINGLLGIAQPGSD--KRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQ .:: ::.:::.:.:::..:..: ::: :.. :.: . : . . ::..: : :.: CCDS65 TDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQ 180 190 200 210 220 230 240 250 260 270 280 pF1KB0 HHLEPLECPFERQHYPEAYASPSHTKGEQGLY--PLPLLNSTLDDGKATLTPSNTPLGRN ..:: :. :::::: . ... : :: . : . ::: ::.:. : :: CCDS65 QQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLA-SPTP---- 240 250 260 270 280 290 300 310 320 330 340 pF1KB0 LSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHA :: .::.:: CCDS65 ----------AD----------------------------------IGSSVP-------- 290 350 360 370 380 390 400 pF1KB0 ASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHT :: .:: .:.:::.::. :.: CCDS65 -------------------GPQ--SYP------------------IVTGSEFSGSPYSHP 300 310 410 420 430 440 450 pF1KB0 PYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDHL ::::...::::: .::.::::::...: .:::..:::.: CCDS65 QYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH 320 330 340 350 >>CCDS65046.1 PAX5 gene_id:5079|Hs108|chr9 (328 aa) initn: 1069 init1: 855 opt: 1141 Z-score: 934.8 bits: 181.7 E(32554): 9.5e-46 Smith-Waterman score: 1141; 59.9% identity (78.3% similar) in 309 aa overlap (2-305:10-307) 10 20 30 40 50 pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLR :..: :.::::.:::::.::::::::.:::::::.:::::::::::::::: CCDS65 MDLEKNYPTPRTS-RTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 VSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLL :::::::::::::::::::.::::::::::::::::::::..:::::::::::::::::: CCDS65 VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 AEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQ :: :::::::::::::::::::::::: : :. . .:... ...:: : . CCDS65 AERVCDNDTVPSVSSINRIIRTKVQQPPNQPVP--------ASSHSIVSTGSVTQVSSVS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 SDSLGSTYSINGLLGIAQPGSD--KRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQ .:: ::.:::.:.:::..:..: ::: :.. :.: . : . . ::..: : :.: CCDS65 TDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQ 180 190 200 210 220 230 240 250 260 270 280 pF1KB0 HHLEPLECPFERQHYPEAYASPSHTKGEQGLY--PLPLLNSTLDDGKATL-TPSNTPLGR ..:: :. :::::: . ... : :: . : . ::: ::.: .:. . .: CCDS65 QQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGS 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB0 NLSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPH .. :.::.:. ::. CCDS65 SVPGPQSYPIVTG--SPYYYSAAARGAAPPAAATAYDRH 300 310 320 >>CCDS65048.1 PAX5 gene_id:5079|Hs108|chr9 (362 aa) initn: 1241 init1: 864 opt: 1141 Z-score: 934.2 bits: 181.7 E(32554): 1e-45 Smith-Waterman score: 1210; 49.0% identity (65.4% similar) in 451 aa overlap (2-448:10-360) 10 20 30 40 50 pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLR :..: :.::::.:::::.::::::::.:::::::.:::::::::::::::: CCDS65 MDLEKNYPTPRTS-RTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 VSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLL :::::::::::::::::::.::::::::::::::::::::..:::::::::::::::::: CCDS65 VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 AEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQ :: :::::::::::::::::::::::: : :. . .:... ...:: : . CCDS65 AERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPA--------SSHSIVSTGSVTQVSSVS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 SDSLGSTYSINGLLGIAQPGSD--KRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQ .:: ::.:::.:.:::..:..: ::: :.. :.: . : . . ::..: : :.: CCDS65 TDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQ 180 190 200 210 220 230 240 250 260 270 280 pF1KB0 HHLEPLECPFERQHYPEAYASPSHTKGEQGLY--PLPLLNSTLDDGKATLTPSNTPLGRN ..:: :. :::::: . ... : :: . : . ::: ::.:. : :: CCDS65 QQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLA-SPTP---- 240 250 260 270 280 290 300 310 320 330 340 pF1KB0 LSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHA :: .::.:: ...: CCDS65 ----------AD----------------------------------IGSSVPGPQSYP-- 290 300 350 360 370 380 390 400 pF1KB0 ASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHT ...::.... ::::::::.: .:::::.. ...::: :: CCDS65 -----------IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGS---------- 310 320 330 410 420 430 440 450 pF1KB0 PYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDHL :::::...: .:::..:::.: CCDS65 -------------------PYYYSAAARGAAPPAAATAYDRH 340 350 360 >>CCDS6607.1 PAX5 gene_id:5079|Hs108|chr9 (391 aa) initn: 1373 init1: 864 opt: 1138 Z-score: 931.2 bits: 181.3 E(32554): 1.5e-45 Smith-Waterman score: 1408; 52.8% identity (71.0% similar) in 451 aa overlap (2-448:10-389) 10 20 30 40 50 pF1KB0 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLR :..: :.::::.:::::.::::::::.:::::::.:::::::::::::::: CCDS66 MDLEKNYPTPRTS-RTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLR 10 20 30 40 50 60 70 80 90 100 110 pF1KB0 VSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLL :::::::::::::::::::.::::::::::::::::::::..:::::::::::::::::: CCDS66 VSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB0 AEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQ :: :::::::::::::::::::::::: : :. . .:... ...:: : . CCDS66 AERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPA--------SSHSIVSTGSVTQVSSVS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 SDSLGSTYSINGLLGIAQPGSD--KRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQ .:: ::.:::.:.:::..:..: ::: :.. :.: . : . . ::..: : :.: CCDS66 TDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQ 180 190 200 210 220 230 240 250 260 270 280 pF1KB0 HHLEPLECPFERQHYPEAYASPSHTKGEQGLY--PLPLLNSTLDDGKATLTPSNTPLGRN ..:: :. :::::: . ... : :: . : . ::: ::.:. : :: CCDS66 QQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLA-SPTP---- 240 250 260 270 280 290 300 310 320 330 340 pF1KB0 LSTHQTYPVVADPHSPFAIKQETPEVSSSSSTPSSLSSSAFLDLQQVGSGVPPFNAFPHA :: .::.:: ...: CCDS66 ----------AD----------------------------------IGSSVPGPQSYP-- 290 300 350 360 370 380 390 400 pF1KB0 ASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYGHT ...::.... ::::::::.: .:::::.. ...::: :::.::. :.: CCDS66 -----------IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHP 310 320 330 340 410 420 430 440 450 pF1KB0 PYSSYSEAWRFPNSSLLSSPYYYSSTSRPSAPPTTATAFDHL ::::...::::: .::.::::::...: .:::..:::.: CCDS66 QYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH 350 360 370 380 390 450 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:39:54 2016 done: Sat Nov 5 17:39:54 2016 Total Scan time: 2.560 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]