Result of FASTA (omim) for
pF1KB0982
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0982, 447 aa
1>>>pF1KB0982 447 - 447 aa - 447 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6326+/-0.000336; mu= 8.7799+/- 0.021
mean_var=180.1788+/-38.048, 0's: 0 Z-trim(120.9): 491 B-trim: 3506 in 2/53
Lambda= 0.095548
statistics sampled from 36067 (36729) to 36067 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.431), width: 16
Scan time: 9.300
The best scores are: opt bits E(85289)
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450) 3041 431.2 2.7e-120
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465) 1006 150.7 7.6e-36
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462) 948 142.7 1.9e-33
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328) 563 89.5 1.4e-17
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331) 563 89.5 1.4e-17
XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B ad ( 366) 563 89.6 1.5e-17
XP_011532740 (OMIM: 104220) PREDICTED: alpha-1B ad ( 389) 563 89.6 1.6e-17
XP_011532739 (OMIM: 104220) PREDICTED: alpha-1B ad ( 402) 563 89.6 1.6e-17
NP_000670 (OMIM: 104220) alpha-1B adrenergic recep ( 520) 563 89.7 2e-17
XP_011532737 (OMIM: 104220) PREDICTED: alpha-1B ad ( 556) 563 89.7 2.1e-17
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 558 88.8 2.2e-17
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317) 558 88.8 2.2e-17
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324) 558 88.8 2.3e-17
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342) 558 88.8 2.4e-17
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370) 558 88.9 2.5e-17
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372) 558 88.9 2.5e-17
XP_006716356 (OMIM: 104221) PREDICTED: alpha-1A ad ( 429) 558 88.9 2.8e-17
NP_150645 (OMIM: 104221) alpha-1A adrenergic recep ( 429) 558 88.9 2.8e-17
NP_150647 (OMIM: 104221) alpha-1A adrenergic recep ( 455) 558 89.0 2.9e-17
NP_000671 (OMIM: 104221) alpha-1A adrenergic recep ( 466) 558 89.0 3e-17
XP_016868584 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 558 89.0 3e-17
XP_006716355 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 558 89.0 3e-17
XP_016868583 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 558 89.0 3e-17
NP_150646 (OMIM: 104221) alpha-1A adrenergic recep ( 475) 558 89.0 3e-17
NP_000515 (OMIM: 109760,614674) 5-hydroxytryptamin ( 422) 528 84.8 4.8e-16
NP_000856 (OMIM: 182132) 5-hydroxytryptamine recep ( 365) 501 81.0 5.7e-15
XP_011534091 (OMIM: 182132) PREDICTED: 5-hydroxytr ( 365) 501 81.0 5.7e-15
NP_000855 (OMIM: 182133) 5-hydroxytryptamine recep ( 377) 497 80.5 8.6e-15
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 497 80.5 8.8e-15
NP_000669 (OMIM: 104219) alpha-1D adrenergic recep ( 572) 499 80.9 9.6e-15
XP_016872785 (OMIM: 126450,159900) PREDICTED: D(2) ( 443) 492 79.8 1.6e-14
NP_000786 (OMIM: 126450,159900) D(2) dopamine rece ( 443) 492 79.8 1.6e-14
NP_057658 (OMIM: 126450,159900) D(2) dopamine rece ( 414) 483 78.6 3.5e-14
NP_001006631 (OMIM: 118493) muscarinic acetylcholi ( 466) 474 77.4 9e-14
NP_001006630 (OMIM: 118493) muscarinic acetylcholi ( 466) 474 77.4 9e-14
NP_001006629 (OMIM: 118493) muscarinic acetylcholi ( 466) 474 77.4 9e-14
XP_011514071 (OMIM: 118493) PREDICTED: muscarinic ( 466) 474 77.4 9e-14
NP_001006633 (OMIM: 118493) muscarinic acetylcholi ( 466) 474 77.4 9e-14
NP_000730 (OMIM: 118493) muscarinic acetylcholine ( 466) 474 77.4 9e-14
NP_001006632 (OMIM: 118493) muscarinic acetylcholi ( 466) 474 77.4 9e-14
NP_001006627 (OMIM: 118493) muscarinic acetylcholi ( 466) 474 77.4 9e-14
NP_001006628 (OMIM: 118493) muscarinic acetylcholi ( 466) 474 77.4 9e-14
NP_062874 (OMIM: 182137) 5-hydroxytryptamine recep ( 432) 456 74.9 4.8e-13
NP_000863 (OMIM: 182137) 5-hydroxytryptamine recep ( 445) 456 74.9 4.9e-13
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479) 456 74.9 5.1e-13
NP_387512 (OMIM: 126451,181500,190300) D(3) dopami ( 367) 453 74.4 5.6e-13
NP_001277738 (OMIM: 126451,181500,190300) D(3) dop ( 400) 453 74.4 6e-13
NP_000787 (OMIM: 126451,181500,190300) D(3) dopami ( 400) 453 74.4 6e-13
NP_001269492 (OMIM: 126451,181500,190300) D(3) dop ( 400) 453 74.4 6e-13
XP_016861318 (OMIM: 126451,181500,190300) PREDICTE ( 400) 453 74.4 6e-13
>>NP_000673 (OMIM: 104260,607876) alpha-2B adrenergic re (450 aa)
initn: 2199 init1: 2030 opt: 3041 Z-score: 2280.8 bits: 431.2 E(85289): 2.7e-120
Smith-Waterman score: 3041; 99.3% identity (99.3% similar) in 450 aa overlap (1-447:1-450)
10 20 30 40 50 60
pF1KB0 MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
250 260 270 280 290 300
310 320 330 340 350
pF1KB0 EEEEEE---CEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRR
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB0 AQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSS
370 380 390 400 410 420
420 430 440
pF1KB0 LNPVIYTIFNQDFRRAFRRILCRPWTQTAW
::::::::::::::::::::::::::::::
NP_000 LNPVIYTIFNQDFRRAFRRILCRPWTQTAW
430 440 450
>>NP_000672 (OMIM: 104210) alpha-2A adrenergic receptor (465 aa)
initn: 1240 init1: 739 opt: 1006 Z-score: 764.6 bits: 150.7 E(85289): 7.6e-36
Smith-Waterman score: 1442; 53.7% identity (72.9% similar) in 447 aa overlap (6-440:42-458)
10 20 30
pF1KB0 MDHQDPYSVQATAAIAAAITFLILFTIFGNALVIL
:::.:.: ... .:.:.:.:::.:::.
NP_000 SFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVII
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB0 AVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLF
::.:::.:.:::::::::::.::::::::.::::::::..::::: ..:::.::::::::
NP_000 AVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLF
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB0 CTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIY----K
:::::::::::::::::....:.::: :::::::: ::.:::.:.::::.::::
NP_000 CTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKG
140 150 160 170 180 190
160 170 180 190 200
pF1KB0 GDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRS-----NRRG
: :::: ..:.:..:.. ::...: :::::::::::::::.::: :::: .:::
NP_000 GGGGPQP-AEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRG
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB0 PRAKGGPGQGESKQPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTG
: : ..: : . ::. : :: . . ..:: . :: . :.::
NP_000 PDAVAAPPGGTER--RPNGLGPERSAGPGGAEAEPLPTQLNG---APGEPAPA-GPRDTD
260 270 280 290 300
270 280 290 300 310 320
pF1KB0 TRALPPSWAALPNSGQGQKEGVCGASPEDEAEEEEEEEEECEPQAVPVSPASACSPPLQQ
. : : .: .... : . :. . . . .: :.:.. : : .
NP_000 ALDLEES----SSSDHAER-------PPGPRRPERGPRGKGKARASQVKPGD--SLPRRG
310 320 330 340 350
330 340 350 360 370 380
pF1KB0 PQGSRVLATLRGQVLLGRG---VGAIGGQWWRRRAQLTREKRFTFVLAVVIGVFVLCWFP
: .. . : : : ::: .. :: : . :::::::::::::::::.::::
NP_000 PGATGI-----GTPAAGPGEERVGAAKASRWRGRQN--REKRFTFVLAVVIGVFVVCWFP
360 370 380 390 400
390 400 410 420 430 440
pF1KB0 FFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRILCRPWT
:::.:.: :. :.::. ::.::::.::::::::::::::::.::::::..::::
NP_000 FFFTYTLTAV---GCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDR
410 420 430 440 450 460
pF1KB0 QTAW
NP_000 KRIV
>>NP_000674 (OMIM: 104250) alpha-2C adrenergic receptor (462 aa)
initn: 1399 init1: 727 opt: 948 Z-score: 721.4 bits: 142.7 E(85289): 1.9e-33
Smith-Waterman score: 1383; 54.8% identity (72.3% similar) in 440 aa overlap (7-440:46-454)
10 20 30
pF1KB0 MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILA
::. :.:..::.. :::.::. ::.::..:
NP_000 AGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB0 VLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFC
:::::.:::::::::::::.::::::::..::::::::..:::: ..:: ::::::::::
NP_000 VLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFC
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB0 TSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGP
::::::::::::::::.:..:.::: ::::::.: :..::::.::::.:::. : :
NP_000 TSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQ-P
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB0 QPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRR--GPRAKGGPG
. . ::: ::.:.::::.: ::::::::::: ::: ::: .:: .: :: ::
NP_000 DGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGP-
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB0 QGESKQPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSW
.: : : ..: :...:.: : ::: . : :....
NP_000 DGAS--PTTENG----------LGAAAGAGE-NGHCAPP--PADVEPDESSAAAERRRRR
260 270 280 290
280 290 300 310 320 330
pF1KB0 AALPNSGQ---GQKEGVCGASPEDEAEEEEEEEEECEPQAVPVSPASACSPPLQQPQGSR
.:: .:. : . :. ::. . . : :. . .: : : :
NP_000 GALRRGGRRRAGAEGGAGGADGQGAG-----------PGAAESGALTASRSP--GPGGRL
300 310 320 330 340
340 350 360 370 380 390
pF1KB0 VLATLRG-QVLLGRGVGAIGGQWWRRRAQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSL
:. :. . .:.: : .. :. :: .::::::::::::.::::::::::::::::
NP_000 SRASSRSVEFFLSRRRRARSSVCRRKVAQ-AREKRFTFVLAVVMGVFVLCWFPFFFSYSL
350 360 370 380 390 400
400 410 420 430 440
pF1KB0 GAICPKHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRILCRPWTQTAW
.:: . :.:: ::.::::::::::::::::::.:::::::.:..:: :
NP_000 YGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
410 420 430 440 450 460
>>XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B adrene (328 aa)
initn: 625 init1: 420 opt: 563 Z-score: 436.5 bits: 89.5 E(85289): 1.4e-17
Smith-Waterman score: 563; 43.6% identity (74.4% similar) in 195 aa overlap (12-204:43-235)
10 20 30
pF1KB0 MDHQDPYSVQATAAIAAAITF--LILFTIFGNALVILAVLT
: ::...... .:::.: :: ::::.:
XP_005 APAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVAC
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB0 SRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSS
.: ::.: : :.:.:: ::.:.. ..::: : :.:::: . : .:... :.::: ::.:
XP_005 NRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTAS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB0 IVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPR
:. :::::.::: .: .:.: . : :. .:.::....:::. ::. : . : :
XP_005 ILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLL--GWKEPAPN
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB0 GRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESK
.: ...: .: : ::.:::. : .....: :.:..:::...
XP_005 DDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKE
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB0 QPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPN
XP_005 LTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPF
260 270 280 290 300 310
>>XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B adrene (331 aa)
initn: 616 init1: 420 opt: 563 Z-score: 436.5 bits: 89.5 E(85289): 1.4e-17
Smith-Waterman score: 563; 43.6% identity (74.4% similar) in 195 aa overlap (12-204:43-235)
10 20 30
pF1KB0 MDHQDPYSVQATAAIAAAITF--LILFTIFGNALVILAVLT
: ::...... .:::.: :: ::::.:
XP_006 APAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVAC
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB0 SRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSS
.: ::.: : :.:.:: ::.:.. ..::: : :.:::: . : .:... :.::: ::.:
XP_006 NRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTAS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB0 IVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPR
:. :::::.::: .: .:.: . : :. .:.::....:::. ::. : . : :
XP_006 ILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLL--GWKEPAPN
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB0 GRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESK
.: ...: .: : ::.:::. : .....: :.:..:::...
XP_006 DDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKE
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB0 QPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPN
XP_006 LTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPF
260 270 280 290 300 310
>>XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B adrene (366 aa)
initn: 616 init1: 420 opt: 563 Z-score: 435.9 bits: 89.6 E(85289): 1.5e-17
Smith-Waterman score: 563; 43.6% identity (74.4% similar) in 195 aa overlap (12-204:43-235)
10 20 30
pF1KB0 MDHQDPYSVQATAAIAAAITF--LILFTIFGNALVILAVLT
: ::...... .:::.: :: ::::.:
XP_005 APAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVAC
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB0 SRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSS
.: ::.: : :.:.:: ::.:.. ..::: : :.:::: . : .:... :.::: ::.:
XP_005 NRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTAS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB0 IVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPR
:. :::::.::: .: .:.: . : :. .:.::....:::. ::. : . : :
XP_005 ILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLL--GWKEPAPN
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB0 GRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESK
.: ...: .: : ::.:::. : .....: :.:..:::...
XP_005 DDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKE
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB0 QPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPN
XP_005 LTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPF
260 270 280 290 300 310
>>XP_011532740 (OMIM: 104220) PREDICTED: alpha-1B adrene (389 aa)
initn: 616 init1: 420 opt: 563 Z-score: 435.5 bits: 89.6 E(85289): 1.6e-17
Smith-Waterman score: 563; 43.6% identity (74.4% similar) in 195 aa overlap (12-204:43-235)
10 20 30
pF1KB0 MDHQDPYSVQATAAIAAAITF--LILFTIFGNALVILAVLT
: ::...... .:::.: :: ::::.:
XP_011 APAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVAC
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB0 SRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSS
.: ::.: : :.:.:: ::.:.. ..::: : :.:::: . : .:... :.::: ::.:
XP_011 NRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTAS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB0 IVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPR
:. :::::.::: .: .:.: . : :. .:.::....:::. ::. : . : :
XP_011 ILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLL--GWKEPAPN
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB0 GRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESK
.: ...: .: : ::.:::. : .....: :.:..:::...
XP_011 DDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKE
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB0 QPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPN
XP_011 LTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPF
260 270 280 290 300 310
>>XP_011532739 (OMIM: 104220) PREDICTED: alpha-1B adrene (402 aa)
initn: 616 init1: 420 opt: 563 Z-score: 435.4 bits: 89.6 E(85289): 1.6e-17
Smith-Waterman score: 563; 43.6% identity (74.4% similar) in 195 aa overlap (12-204:43-235)
10 20 30
pF1KB0 MDHQDPYSVQATAAIAAAITF--LILFTIFGNALVILAVLT
: ::...... .:::.: :: ::::.:
XP_011 APAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVAC
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB0 SRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSS
.: ::.: : :.:.:: ::.:.. ..::: : :.:::: . : .:... :.::: ::.:
XP_011 NRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTAS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB0 IVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPR
:. :::::.::: .: .:.: . : :. .:.::....:::. ::. : . : :
XP_011 ILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLL--GWKEPAPN
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB0 GRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESK
.: ...: .: : ::.:::. : .....: :.:..:::...
XP_011 DDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKE
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB0 QPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPN
XP_011 LTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPF
260 270 280 290 300 310
>>NP_000670 (OMIM: 104220) alpha-1B adrenergic receptor (520 aa)
initn: 795 init1: 424 opt: 563 Z-score: 433.9 bits: 89.7 E(85289): 2e-17
Smith-Waterman score: 624; 31.6% identity (55.5% similar) in 434 aa overlap (12-440:43-368)
10 20 30
pF1KB0 MDHQDPYSVQATAAIAAAITF--LILFTIFGNALVILAVLT
: ::...... .:::.: :: ::::.:
NP_000 APAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVAC
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB0 SRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSS
.: ::.: : :.:.:: ::.:.. ..::: : :.:::: . : .:... :.::: ::.:
NP_000 NRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTAS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB0 IVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPR
:. :::::.::: .: .:.: . : :. .:.::....:::. ::. : . : :
NP_000 ILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLL--GWKEPAPN
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB0 GRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESK
.: ...: .: : ::.:::. : .....: :.:..:::... : :
NP_000 DDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLE-------AGVMK
200 210 220 230 240
220 230 240 250 260 270
pF1KB0 QPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPN
. ....: .: :::. : :: : .
NP_000 E--------MSNSKELTLRI---------HSKNFHE--------DT-----------LSS
250 260
280 290 300 310 320 330
pF1KB0 SGQGQKEGVCGASPEDEAEEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQ
. . .: ..:..: .. ..
NP_000 T---KAKG-------------------------------------HNPRSSIAVKLFK--
270 280
340 350 360 370 380 390
pF1KB0 VLLGRGVGAIGGQWWRRRAQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCK
..:::. . .:..:.:.:.:::.:::.. ::.. . :
NP_000 --------------------FSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLF-STLK
290 300 310 320
400 410 420 430 440
pF1KB0 VPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRIL---CRPWTQTAW
: ..:. ::.:: :: :::.:: ...:.::: ::: ::
NP_000 PPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRRRLGGC
330 340 350 360 370 380
NP_000 AYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRTLPSASPSPGYLGRGAPPPVELCAF
390 400 410 420 430 440
>>XP_011532737 (OMIM: 104220) PREDICTED: alpha-1B adrene (556 aa)
initn: 780 init1: 420 opt: 563 Z-score: 433.5 bits: 89.7 E(85289): 2.1e-17
Smith-Waterman score: 565; 31.4% identity (55.8% similar) in 439 aa overlap (12-440:43-404)
10 20 30
pF1KB0 MDHQDPYSVQATAAIAAAITF--LILFTIFGNALVILAVLT
: ::...... .:::.: :: ::::.:
XP_011 APAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVAC
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB0 SRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSS
.: ::.: : :.:.:: ::.:.. ..::: : :.:::: . : .:... :.::: ::.:
XP_011 NRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTAS
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB0 IVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPR
:. :::::.::: .: .:.: . : :. .:.::....:::. ::. : . : :
XP_011 ILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLL--GWKEPAPN
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB0 GRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESK
.: ...: .: : ::.:::. : .....: :.:..:::... : :
XP_011 DDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLE-------AGVMK
200 210 220 230 240
220 230 240 250 260 270
pF1KB0 QPRPDHGGALASAKLPALASVASAREVNGHSKS-TGEKEEGETPEDT-GTRALPPSWAAL
. ....: .: . : : : . .. : .:..:... ... . :
XP_011 E--------MSNSKELTL-RIHSK---NFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKK
250 260 270 280 290
280 290 300 310 320 330
pF1KB0 PNSGQGQKEGVCGASPEDEAEEEEEEEEECE-P--QAVPVSPASACSPPLQQPQGSRVLA
. : :. : : :.:..: : :: : ::.
XP_011 AAKTLGIVVGMFIL---------------CWLPFFIALPLDPDS---PP---PTHLRVVP
300 310 320 330
340 350 360 370 380 390
pF1KB0 TLRGQVLLGRGVGAIGGQWWRRRAQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAIC
. : . . .. : .:. :. . : :..
XP_011 AP-----------------WGHSSIMN--------LPLVL--------PLDATRS-GSLF
340 350
400 410 420 430 440
pF1KB0 PKHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRIL---CRPWTQTAW
. : : ..:. ::.:: :: :::.:: ...:.::: ::: ::
XP_011 -STLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRR
360 370 380 390 400 410
XP_011 RLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRTLPSASPSPGYLGRGAPPPV
420 430 440 450 460 470
447 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:40:30 2016 done: Sat Nov 5 17:40:31 2016
Total Scan time: 9.300 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]