FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0994, 461 aa 1>>>pF1KB0994 461 - 461 aa - 461 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8710+/-0.000345; mu= 16.3634+/- 0.021 mean_var=124.0234+/-25.918, 0's: 0 Z-trim(116.9): 156 B-trim: 119 in 1/52 Lambda= 0.115166 statistics sampled from 28277 (28504) to 28277 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.334), width: 16 Scan time: 9.970 The best scores are: opt bits E(85289) NP_009005 (OMIM: 605000,615401) coronin-1A [Homo s ( 461) 3136 532.5 9.4e-151 NP_001180262 (OMIM: 605000,615401) coronin-1A [Hom ( 461) 3136 532.5 9.4e-151 XP_011544016 (OMIM: 605000,615401) PREDICTED: coro ( 461) 3136 532.5 9.4e-151 XP_016878374 (OMIM: 605000,615401) PREDICTED: coro ( 463) 2933 498.7 1.3e-140 XP_016878375 (OMIM: 605000,615401) PREDICTED: coro ( 463) 2933 498.7 1.3e-140 NP_065174 (OMIM: 609849) coronin-1B [Homo sapiens] ( 489) 2190 375.3 2e-103 NP_001018080 (OMIM: 609849) coronin-1B [Homo sapie ( 489) 2190 375.3 2e-103 NP_055140 (OMIM: 605269) coronin-1C isoform b [Hom ( 474) 2155 369.5 1.1e-101 XP_016874612 (OMIM: 605269) PREDICTED: coronin-1C ( 474) 2155 369.5 1.1e-101 XP_016874611 (OMIM: 605269) PREDICTED: coronin-1C ( 474) 2155 369.5 1.1e-101 NP_001263400 (OMIM: 605269) coronin-1C isoform b [ ( 474) 2155 369.5 1.1e-101 XP_016874610 (OMIM: 605269) PREDICTED: coronin-1C ( 527) 2155 369.5 1.2e-101 NP_001098707 (OMIM: 605269) coronin-1C isoform a [ ( 527) 2155 369.5 1.2e-101 NP_001310944 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63 NP_001310943 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63 NP_001177386 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63 NP_001177385 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 1381 240.9 5.8e-63 NP_006082 (OMIM: 605002) coronin-2B isoform 1 [Hom ( 480) 1381 240.9 5.8e-63 NP_003380 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 1349 235.6 2.5e-61 NP_438171 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 1349 235.6 2.5e-61 XP_011517288 (OMIM: 602159) PREDICTED: coronin-2A ( 525) 1349 235.6 2.5e-61 XP_011536427 (OMIM: 605269) PREDICTED: coronin-1C ( 286) 1046 185.0 2.3e-46 NP_078811 (OMIM: 611668) coronin-7 isoform 1 [Homo ( 925) 740 134.7 1e-30 NP_001188401 (OMIM: 611668) coronin-7 isoform 2 [H ( 907) 648 119.4 4.1e-26 NP_001188402 (OMIM: 611668) coronin-7 isoform 3 [H ( 840) 538 101.1 1.2e-20 NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 194 43.5 0.0011 XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 194 43.5 0.0011 NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 194 43.5 0.0011 XP_016863186 (OMIM: 609005) PREDICTED: WD repeat-c ( 982) 199 44.8 0.0012 NP_115737 (OMIM: 606929) THO complex subunit 3 [Ho ( 351) 192 43.2 0.0014 XP_005262782 (OMIM: 609005) PREDICTED: WD repeat-c (1216) 199 44.9 0.0014 NP_851782 (OMIM: 609005) WD repeat-containing prot (1283) 199 45.0 0.0015 XP_011529884 (OMIM: 609005) PREDICTED: WD repeat-c (1290) 199 45.0 0.0015 XP_016863178 (OMIM: 609005) PREDICTED: WD repeat-c (1307) 199 45.0 0.0015 XP_016863177 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 199 45.0 0.0015 XP_016863175 (OMIM: 609005) PREDICTED: WD repeat-c (1314) 199 45.0 0.0015 NP_733828 (OMIM: 609005) WD repeat-containing prot (1322) 199 45.0 0.0015 NP_056975 (OMIM: 605585) pre-mRNA-processing facto ( 579) 192 43.4 0.0019 NP_055317 (OMIM: 608330) pre-mRNA-processing facto ( 504) 190 43.0 0.0022 XP_011519465 (OMIM: 604447) PREDICTED: guanine nuc ( 301) 182 41.4 0.0039 XP_011519464 (OMIM: 604447) PREDICTED: guanine nuc ( 353) 182 41.5 0.0044 NP_006569 (OMIM: 604447) guanine nucleotide-bindin ( 353) 182 41.5 0.0044 NP_057278 (OMIM: 604447) guanine nucleotide-bindin ( 395) 182 41.6 0.0047 XP_005258020 (OMIM: 610091) PREDICTED: WD repeat a ( 216) 178 40.6 0.005 XP_016879923 (OMIM: 610091) PREDICTED: WD repeat a ( 216) 178 40.6 0.005 NP_004795 (OMIM: 604333) probable cytosolic iron-s ( 339) 178 40.8 0.0068 >>NP_009005 (OMIM: 605000,615401) coronin-1A [Homo sapie (461 aa) initn: 3136 init1: 3136 opt: 3136 Z-score: 2827.5 bits: 532.5 E(85289): 9.4e-151 Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461) 10 20 30 40 50 60 pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE 370 380 390 400 410 420 430 440 450 460 pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK ::::::::::::::::::::::::::::::::::::::::: NP_009 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK 430 440 450 460 >>NP_001180262 (OMIM: 605000,615401) coronin-1A [Homo sa (461 aa) initn: 3136 init1: 3136 opt: 3136 Z-score: 2827.5 bits: 532.5 E(85289): 9.4e-151 Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461) 10 20 30 40 50 60 pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE 370 380 390 400 410 420 430 440 450 460 pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK ::::::::::::::::::::::::::::::::::::::::: NP_001 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK 430 440 450 460 >>XP_011544016 (OMIM: 605000,615401) PREDICTED: coronin- (461 aa) initn: 3136 init1: 3136 opt: 3136 Z-score: 2827.5 bits: 532.5 E(85289): 9.4e-151 Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 461 aa overlap (1-461:1-461) 10 20 30 40 50 60 pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE 370 380 390 400 410 420 430 440 450 460 pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK ::::::::::::::::::::::::::::::::::::::::: XP_011 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK 430 440 450 460 >>XP_016878374 (OMIM: 605000,615401) PREDICTED: coronin- (463 aa) initn: 2933 init1: 2933 opt: 2933 Z-score: 2645.2 bits: 498.7 E(85289): 1.3e-140 Smith-Waterman score: 2933; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE 370 380 390 400 410 420 430 440 450 460 pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK ::::::: XP_016 ASGTPSSVRGLGSQGIKLGGWGGAGVWGTSNSQHWESLWVREW 430 440 450 460 >>XP_016878375 (OMIM: 605000,615401) PREDICTED: coronin- (463 aa) initn: 2933 init1: 2933 opt: 2933 Z-score: 2645.2 bits: 498.7 E(85289): 1.3e-140 Smith-Waterman score: 2933; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427) 10 20 30 40 50 60 pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPE 370 380 390 400 410 420 430 440 450 460 pF1KB0 ASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK ::::::: XP_016 ASGTPSSVRGLGSQGIKLGGWGGAGVWGTSNSQHWESLWVREW 430 440 450 460 >>NP_065174 (OMIM: 609849) coronin-1B [Homo sapiens] (489 aa) initn: 2244 init1: 1235 opt: 2190 Z-score: 1977.7 bits: 375.3 E(85289): 2e-103 Smith-Waterman score: 2217; 66.5% identity (86.2% similar) in 477 aa overlap (3-456:4-479) 10 20 30 40 50 pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAF :.:::.::::::::::.: ::::::.:::..:::: ::::::::.:.: :::::::: NP_065 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 LVLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLP :::::.::::.:: :::::::.::::: ::::::.::::::::::::::.::..:: : NP_065 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 LREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTI : ::::.::::::::::.::: ::.:::::::::::...:.:::. . : .::: : NP_065 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDS-LHPDLI 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 YSVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGF :.:.:...:.:.:..:.:: ::::.::.::.:::... :::.::.::.:...::..:::: NP_065 YNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGF 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 SRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITS :::::::.:::: ..::::..:::::.:.:.::::.::::..::.:::::::::::::: NP_065 SRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 EAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLF : :..:.:. :.::: ::::: ::::::::.:::::::::::::.::::.:::::::::: NP_065 EPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB0 QEDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LDTGRRRA :.:::: ::::. :: ::::..:::: :.::::...::: :.:.:...: :. .: NP_065 QDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAM 360 370 380 390 400 410 420 430 440 450 pF1KB0 APEAS--GTPSS-----DAV-----------SRLEE---EMRKLQATVQELQKRLDRLEE :: .: :.:.: ::. ..::: :.: :.: :.: :. :::: NP_065 APGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEE 420 430 440 450 460 470 460 pF1KB0 TVQAK NP_065 QLGRMENGDA 480 >>NP_001018080 (OMIM: 609849) coronin-1B [Homo sapiens] (489 aa) initn: 2244 init1: 1235 opt: 2190 Z-score: 1977.7 bits: 375.3 E(85289): 2e-103 Smith-Waterman score: 2217; 66.5% identity (86.2% similar) in 477 aa overlap (3-456:4-479) 10 20 30 40 50 pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAF :.:::.::::::::::.: ::::::.:::..:::: ::::::::.:.: :::::::: NP_001 MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 LVLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLP :::::.::::.:: :::::::.::::: ::::::.::::::::::::::.::..:: : NP_001 LVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB0 LREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTI : ::::.::::::::::.::: ::.:::::::::::...:.:::. . : .::: : NP_001 LTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDS-LHPDLI 130 140 150 160 170 180 190 200 210 220 230 pF1KB0 YSVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGF :.:.:...:.:.:..:.:: ::::.::.::.:::... :::.::.::.:...::..:::: NP_001 YNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGF 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB0 SRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITS :::::::.:::: ..::::..:::::.:.:.::::.::::..::.:::::::::::::: NP_001 SRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB0 EAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLF : :..:.:. :.::: ::::: ::::::::.:::::::::::::.::::.:::::::::: NP_001 EPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB0 QEDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LDTGRRRA :.:::: ::::. :: ::::..:::: :.::::...::: :.:.:...: :. .: NP_001 QDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAM 360 370 380 390 400 410 420 430 440 450 pF1KB0 APEAS--GTPSS-----DAV-----------SRLEE---EMRKLQATVQELQKRLDRLEE :: .: :.:.: ::. ..::: :.: :.: :.: :. :::: NP_001 APGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEE 420 430 440 450 460 470 460 pF1KB0 TVQAK NP_001 QLGRMENGDA 480 >>NP_055140 (OMIM: 605269) coronin-1C isoform b [Homo sa (474 aa) initn: 2181 init1: 1198 opt: 2155 Z-score: 1946.4 bits: 369.5 E(85289): 1.1e-101 Smith-Waterman score: 2170; 65.3% identity (88.0% similar) in 467 aa overlap (3-456:2-467) 10 20 30 40 50 60 pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL :.:::.::::::::: .: ::::.:.:::..::::.::::::.:::.: ::::::::: NP_055 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFL 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL :::: ::::.::. :::::::.::::: ::::::.::::::::::::::.::..:: : : NP_055 VLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY :::: ::::.::::::::: ::.::::::::::.:..:.:::: :...: ..: : :: NP_055 TEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS .:.:.:.:.::::. .::.::.:.::: .::::.. :::.::.::.:...:...::::: NP_055 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE ::::::.:::. :...::..:.:.:::.::::::.::::.:.::::::::::::::::.: NP_055 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ .:..:::. ::::: ::::::::::::.:::::::::.:::::.:::: ::::::::::: NP_055 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ 300 310 320 330 340 350 370 380 390 400 410 pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD---TGRR .:::: ::::. :: ::::. :..: :.::::: ::.: :.:.:.: . :: :. . NP_055 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANK 360 370 380 390 400 410 420 430 440 450 460 pF1KB0 R----AAPE-ASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEETVQAK . . :. .. : : . ..:.: :..... :. . ..:...::. NP_055 KCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA 420 430 440 450 460 470 >>XP_016874612 (OMIM: 605269) PREDICTED: coronin-1C isof (474 aa) initn: 2181 init1: 1198 opt: 2155 Z-score: 1946.4 bits: 369.5 E(85289): 1.1e-101 Smith-Waterman score: 2170; 65.3% identity (88.0% similar) in 467 aa overlap (3-456:2-467) 10 20 30 40 50 60 pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL :.:::.::::::::: .: ::::.:.:::..::::.::::::.:::.: ::::::::: XP_016 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFL 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL :::: ::::.::. :::::::.::::: ::::::.::::::::::::::.::..:: : : XP_016 VLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY :::: ::::.::::::::: ::.::::::::::.:..:.:::: :...: ..: : :: XP_016 TEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS .:.:.:.:.::::. .::.::.:.::: .::::.. :::.::.::.:...:...::::: XP_016 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE ::::::.:::. :...::..:.:.:::.::::::.::::.:.::::::::::::::::.: XP_016 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ .:..:::. ::::: ::::::::::::.:::::::::.:::::.:::: ::::::::::: XP_016 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ 300 310 320 330 340 350 370 380 390 400 410 pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD---TGRR .:::: ::::. :: ::::. :..: :.::::: ::.: :.:.:.: . :: :. . XP_016 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANK 360 370 380 390 400 410 420 430 440 450 460 pF1KB0 R----AAPE-ASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEETVQAK . . :. .. : : . ..:.: :..... :. . ..:...::. XP_016 KCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA 420 430 440 450 460 470 >>XP_016874611 (OMIM: 605269) PREDICTED: coronin-1C isof (474 aa) initn: 2181 init1: 1198 opt: 2155 Z-score: 1946.4 bits: 369.5 E(85289): 1.1e-101 Smith-Waterman score: 2170; 65.3% identity (88.0% similar) in 467 aa overlap (3-456:2-467) 10 20 30 40 50 60 pF1KB0 MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFL :.:::.::::::::: .: ::::.:.:::..::::.::::::.:::.: ::::::::: XP_016 MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFL 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 VLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPL :::: ::::.::. :::::::.::::: ::::::.::::::::::::::.::..:: : : XP_016 VLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB0 REPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIY :::: ::::.::::::::: ::.::::::::::.:..:.:::: :...: ..: : :: XP_016 TEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLD-DMHSDMIY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB0 SVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFS .:.:.:.:.::::. .::.::.:.::: .::::.. :::.::.::.:...:...::::: XP_016 NVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB0 RMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSE ::::::.:::. :...::..:.:.:::.::::::.::::.:.::::::::::::::::.: XP_016 RMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB0 APFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQ .:..:::. ::::: ::::::::::::.:::::::::.:::::.:::: ::::::::::: XP_016 SPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQ 300 310 320 330 340 350 370 380 390 400 410 pF1KB0 EDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRG--LD---TGRR .:::: ::::. :: ::::. :..: :.::::: ::.: :.:.:.: . :: :. . XP_016 DDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANK 360 370 380 390 400 410 420 430 440 450 460 pF1KB0 R----AAPE-ASGTPSSDAVSRLEE---EMRKLQATVQELQKRLDRLEETVQAK . . :. .. : : . ..:.: :..... :. . ..:...::. XP_016 KCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA 420 430 440 450 460 470 461 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:43:32 2016 done: Sat Nov 5 17:43:33 2016 Total Scan time: 9.970 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]