FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0995, 284 aa 1>>>pF1KB0995 284 - 284 aa - 284 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.8032+/-0.0016; mu= -5.1401+/- 0.093 mean_var=369.2060+/-90.495, 0's: 0 Z-trim(107.4): 112 B-trim: 470 in 1/49 Lambda= 0.066748 statistics sampled from 9458 (9553) to 9458 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.293), width: 16 Scan time: 2.250 The best scores are: opt bits E(32554) CCDS5035.1 FHL5 gene_id:9457|Hs108|chr6 ( 284) 2151 221.2 6.8e-58 CCDS2070.1 FHL2 gene_id:2274|Hs108|chr2 ( 279) 1383 147.2 1.2e-35 CCDS30678.1 FHL3 gene_id:2275|Hs108|chr1 ( 280) 1176 127.3 1.2e-29 CCDS14655.1 FHL1 gene_id:2273|Hs108|chrX ( 280) 1010 111.3 8e-25 CCDS55506.1 FHL1 gene_id:2273|Hs108|chrX ( 296) 1010 111.3 8.3e-25 CCDS55505.1 FHL1 gene_id:2273|Hs108|chrX ( 309) 1010 111.4 8.5e-25 CCDS55507.1 FHL1 gene_id:2273|Hs108|chrX ( 323) 868 97.7 1.1e-20 CCDS76036.1 FHL1 gene_id:2273|Hs108|chrX ( 194) 616 73.2 1.7e-13 CCDS83493.1 FHL1 gene_id:2273|Hs108|chrX ( 210) 616 73.2 1.8e-13 >>CCDS5035.1 FHL5 gene_id:9457|Hs108|chr6 (284 aa) initn: 2151 init1: 2151 opt: 2151 Z-score: 1152.9 bits: 221.2 E(32554): 6.8e-58 Smith-Waterman score: 2151; 99.6% identity (100.0% similar) in 284 aa overlap (1-284:1-284) 10 20 30 40 50 60 pF1KB0 MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 HWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 HWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 NYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 NYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 LWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICF ::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::: CCDS50 LWHKECFLCSGCRKDLCEEQFMSRDDYPFCVDCYNHLYANKCVACSKPISGLTGAKFICF 190 200 210 220 230 240 250 260 270 280 pF1KB0 QDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI :::::::::::::::::::::::::::::::::::::::::::: CCDS50 QDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI 250 260 270 280 >>CCDS2070.1 FHL2 gene_id:2274|Hs108|chr2 (279 aa) initn: 1798 init1: 1346 opt: 1383 Z-score: 753.3 bits: 147.2 E(32554): 1.2e-35 Smith-Waterman score: 1383; 59.4% identity (85.3% similar) in 278 aa overlap (3-280:2-279) 10 20 30 40 50 60 pF1KB0 MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDR : .: :..:. ::.::::.:...:::::.:.. .:.: :::: ::: : ::: :::: CCDS20 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDR 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 HWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKG ::::.::.:..: .:::.::::::...::::.::::: :::: .::.:::::.::::.:: CCDS20 HWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB0 NYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQ . ::::::.:. :.:::::: .: :.. :.::::.::. : : ::: ::.::.:. .: CCDS20 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB0 LWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICF ::::::.:..:::.: ..: .:::. .:..:. :::.::..:..::::: :.:.: : CCDS20 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 180 190 200 210 220 230 250 260 270 280 pF1KB0 QDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI .. :::..:::: :::.::::.::::. .:.: ::. . CCDS20 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 240 250 260 270 >>CCDS30678.1 FHL3 gene_id:2275|Hs108|chr1 (280 aa) initn: 1615 init1: 1149 opt: 1176 Z-score: 645.5 bits: 127.3 E(32554): 1.2e-29 Smith-Waterman score: 1176; 48.3% identity (80.1% similar) in 271 aa overlap (6-276:5-275) 10 20 30 40 50 60 pF1KB0 MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDR : : :. :: :.::. :..:::: ::: .:.: : ::.. : ::..: :.:: CCDS30 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDR 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 HWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKG :.:::::.: .:..::...::. .: .:::..:: . ::.: : .:.::::::.:. : CCDS30 HFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB0 NYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQ . ::: ::.: .:.::.:.. .. ....:::::.:..:: : :.:..:.::.:. :: CCDS30 QTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB0 LWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICF ::.::..:.::. : .:: :::. :.:. :...:.: :: .:..:: :: :.:.. : CCDS30 PWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSF 180 190 200 210 220 230 250 260 270 280 pF1KB0 QDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI .: .:: .::.:..::.::::.::. .. ...:: : CCDS30 EDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQAGP 240 250 260 270 280 >>CCDS14655.1 FHL1 gene_id:2273|Hs108|chrX (280 aa) initn: 1123 init1: 850 opt: 1010 Z-score: 559.1 bits: 111.3 E(32554): 8e-25 Smith-Waterman score: 1010; 43.8% identity (73.9% similar) in 276 aa overlap (6-280:5-280) 10 20 30 40 50 60 pF1KB0 MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDR : :.:: : ::::: :: :. :.:. .: : ::.::: .:::.. ::.: CCDS14 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNR 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 HWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKG ::. ::.:.:: : :... :.:::...::..: . : : :: : ..:. :....:.:: CCDS14 FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB0 NYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQ . ::. ::.: ::.: ::: .. : ::: : : .::..: :.:.:::::::. :: CCDS14 TVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQ 120 130 140 150 160 170 190 200 210 220 230 pF1KB0 LWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGL-TGAKFIC :: .::.: : : : ..: . .: .:.:::... :.::..:..::.:. :.. . CCDS14 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVA 180 190 200 210 220 230 240 250 260 270 280 pF1KB0 FQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI .. ..::. ::.: ::::.:..: :. ......: :.. . CCDS14 YEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 240 250 260 270 280 >>CCDS55506.1 FHL1 gene_id:2273|Hs108|chrX (296 aa) initn: 1123 init1: 850 opt: 1010 Z-score: 558.8 bits: 111.3 E(32554): 8.3e-25 Smith-Waterman score: 1010; 43.8% identity (73.9% similar) in 276 aa overlap (6-280:21-296) 10 20 30 40 pF1KB0 MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECK : :.:: : ::::: :: :. :.:. .: : ::. CCDS55 MASHRHSGPSSYKVGTMAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECR 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB0 KPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHC ::: .:::.. ::.: ::. ::.:.:: : :... :.:::...::..: . : : :: : CCDS55 KPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB0 KRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNF ..:. :....:.::. ::. ::.: ::.: ::: .. : ::: : : .::..: CCDS55 FKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVK 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB0 CKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVAC :.:.:::::::. :: :: .::.: : : : ..: . .: .:.:::... :.::..: CCDS55 CNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB0 SKPISGL-TGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI ..::.:. :.. . .. ..::. ::.: ::::.:..: :. ......: :.. . CCDS55 KNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 250 260 270 280 290 >>CCDS55505.1 FHL1 gene_id:2273|Hs108|chrX (309 aa) initn: 1123 init1: 850 opt: 1010 Z-score: 558.6 bits: 111.4 E(32554): 8.5e-25 Smith-Waterman score: 1010; 43.8% identity (73.9% similar) in 276 aa overlap (6-280:34-309) 10 20 30 pF1KB0 MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDR : :.:: : ::::: :: :. :.:. CCDS55 YVASLALELIWMLSSPAGPSSYKVGTMAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB0 VFSNYCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYS .: : ::.::: .:::.. ::.: ::. ::.:.:: : :... :.:::...::..: . CCDS55 FCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTT 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB0 NECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCF : : :: : ..:. :....:.::. ::. ::.: ::.: ::: .. : ::: : CCDS55 REDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCH 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB0 EKEFAHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYN : .::..: :.:.:::::::. :: :: .::.: : : : ..: . .: .:.:::. CCDS55 ETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB0 HLYANKCVACSKPISGL-TGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQ .. :.::..:..::.:. :.. . .. ..::. ::.: ::::.:..: :. ......: CCDS55 NFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCP 250 260 270 280 290 300 280 pF1KB0 KCGSGMDTDI :.. . CCDS55 DCAKKL >>CCDS55507.1 FHL1 gene_id:2273|Hs108|chrX (323 aa) initn: 868 init1: 868 opt: 868 Z-score: 484.5 bits: 97.7 E(32554): 1.1e-20 Smith-Waterman score: 868; 46.9% identity (73.5% similar) in 226 aa overlap (6-231:5-230) 10 20 30 40 50 60 pF1KB0 MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDR : :.:: : ::::: :: :. :.:. .: : ::.::: .:::.. ::.: CCDS55 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNR 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 HWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKG ::. ::.:.:: : :... :.:::...::..: . : : :: : ..:. :....:.:: CCDS55 FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB0 NYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQ . ::. ::.: ::.: ::: .. : ::: : : .::..: :.:.:::::::. :: CCDS55 TVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB0 LWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICF :: .::.: : : : ..: . .: .:.:::... :.::..:..::.: CCDS55 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSH 180 190 200 210 220 230 250 260 270 280 pF1KB0 QDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI CCDS55 PVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLV 240 250 260 270 280 290 >>CCDS76036.1 FHL1 gene_id:2273|Hs108|chrX (194 aa) initn: 728 init1: 585 opt: 616 Z-score: 355.9 bits: 73.2 E(32554): 1.7e-13 Smith-Waterman score: 616; 46.6% identity (71.8% similar) in 163 aa overlap (6-168:5-167) 10 20 30 40 50 60 pF1KB0 MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDR : :.:: : ::::: :: :. :.:. .: : ::.::: .:::.. ::.: CCDS76 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNR 10 20 30 40 50 70 80 90 100 110 120 pF1KB0 HWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKG ::. ::.:.:: : :... :.:::...::..: . : : :: : ..:. :....:.:: CCDS76 FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKG 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB0 NYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQ . ::. ::.: ::.: ::: .. : ::: : : .::..: :.: CCDS76 TVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB0 LWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICF CCDS76 DNPGTTTASTAKNAP 180 190 >>CCDS83493.1 FHL1 gene_id:2273|Hs108|chrX (210 aa) initn: 728 init1: 585 opt: 616 Z-score: 355.5 bits: 73.2 E(32554): 1.8e-13 Smith-Waterman score: 616; 46.6% identity (71.8% similar) in 163 aa overlap (6-168:21-183) 10 20 30 40 pF1KB0 MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECK : :.:: : ::::: :: :. :.:. .: : ::. CCDS83 MASHRHSGPSSYKVGTMAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECR 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB0 KPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHC ::: .:::.. ::.: ::. ::.:.:: : :... :.:::...::..: . : : :: : CCDS83 KPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB0 KRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNF ..:. :....:.::. ::. ::.: ::.: ::: .. : ::: : : .::..: CCDS83 FKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVK 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB0 CKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVAC :.: CCDS83 CNKGLVKAPVWWPMKDNPGTTTASTAKNAP 190 200 210 284 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:44:06 2016 done: Sat Nov 5 17:44:07 2016 Total Scan time: 2.250 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]