Result of FASTA (omim) for
pF1KB0996
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0996, 465 aa
1>>>pF1KB0996 465 - 465 aa - 465 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8682+/-0.000482; mu= 11.9243+/- 0.030
mean_var=189.0312+/-40.508, 0's: 0 Z-trim(116.0): 248 B-trim: 1198 in 2/53
Lambda= 0.093284
statistics sampled from 26517 (26817) to 26517 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.314), width: 16
Scan time: 8.020
The best scores are: opt bits E(85289)
NP_003132 (OMIM: 109092) E3 ubiquitin-protein liga ( 475) 1191 173.2 1.3e-42
NP_660215 (OMIM: 607868) E3 ubiquitin-protein liga ( 468) 1092 159.9 1.4e-38
XP_016857901 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 467) 1079 158.2 4.5e-38
NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488) 1021 150.4 1e-35
XP_006711842 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 921 136.9 1.2e-31
NP_057186 (OMIM: 606123) E3 ubiquitin-protein liga ( 477) 921 136.9 1.2e-31
NP_001020111 (OMIM: 606123) E3 ubiquitin-protein l ( 477) 921 136.9 1.2e-31
XP_011542512 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 921 136.9 1.2e-31
XP_011542511 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 477) 921 136.9 1.2e-31
NP_477514 (OMIM: 607564) tripartite motif-containi ( 488) 846 126.8 1.3e-28
NP_001003818 (OMIM: 607564) tripartite motif-conta ( 516) 846 126.9 1.3e-28
XP_011542513 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 450) 825 124.0 8.7e-28
NP_060543 (OMIM: 613184) E3 ubiquitin-protein liga ( 485) 790 119.3 2.4e-26
NP_006065 (OMIM: 606559) E3 ubiquitin-protein liga ( 498) 750 113.9 1e-24
NP_001186502 (OMIM: 606559) E3 ubiquitin-protein l ( 494) 723 110.3 1.2e-23
NP_067629 (OMIM: 605684) tripartite motif-containi ( 488) 720 109.9 1.6e-23
NP_001003827 (OMIM: 605684) tripartite motif-conta ( 488) 720 109.9 1.6e-23
NP_149023 (OMIM: 608487) tripartite motif-containi ( 493) 684 105.0 4.7e-22
XP_005253240 (OMIM: 608487) PREDICTED: tripartite ( 493) 684 105.0 4.7e-22
NP_065091 (OMIM: 606124) tripartite motif-containi ( 452) 639 98.9 3e-20
XP_016873951 (OMIM: 608487) PREDICTED: tripartite ( 300) 632 97.8 4.4e-20
XP_005253241 (OMIM: 608487) PREDICTED: tripartite ( 326) 632 97.8 4.6e-20
NP_149084 (OMIM: 608487) tripartite motif-containi ( 326) 632 97.8 4.6e-20
NP_149083 (OMIM: 608487) tripartite motif-containi ( 347) 632 97.8 4.8e-20
XP_006718421 (OMIM: 608487) PREDICTED: tripartite ( 265) 621 96.2 1.1e-19
XP_016873952 (OMIM: 608487) PREDICTED: tripartite ( 265) 621 96.2 1.1e-19
XP_011518728 (OMIM: 608487) PREDICTED: tripartite ( 310) 621 96.3 1.3e-19
XP_016873950 (OMIM: 608487) PREDICTED: tripartite ( 310) 621 96.3 1.3e-19
XP_011518729 (OMIM: 608487) PREDICTED: tripartite ( 271) 617 95.7 1.7e-19
XP_016873949 (OMIM: 608487) PREDICTED: tripartite ( 314) 605 94.2 5.6e-19
NP_569074 (OMIM: 605684) tripartite motif-containi ( 270) 583 91.1 4e-18
NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518) 583 91.5 6e-18
NP_001268380 (OMIM: 612548) E3 ubiquitin-protein l ( 487) 581 91.2 7e-18
NP_835226 (OMIM: 612548) E3 ubiquitin-protein liga ( 487) 581 91.2 7e-18
XP_011542587 (OMIM: 607868) PREDICTED: E3 ubiquiti ( 391) 570 89.6 1.7e-17
NP_001291425 (OMIM: 613184) E3 ubiquitin-protein l ( 262) 565 88.7 2.1e-17
XP_011514091 (OMIM: 612548) PREDICTED: E3 ubiquiti ( 486) 569 89.5 2.1e-17
NP_001268379 (OMIM: 612548) E3 ubiquitin-protein l ( 486) 569 89.5 2.1e-17
NP_001229732 (OMIM: 613595) butyrophilin subfamily ( 374) 553 87.3 8e-17
NP_932078 (OMIM: 613595) butyrophilin subfamily 3 ( 535) 552 87.3 1.1e-16
NP_008925 (OMIM: 613595) butyrophilin subfamily 3 ( 584) 552 87.3 1.2e-16
NP_001008275 (OMIM: 613288) tripartite motif-conta ( 477) 549 86.8 1.4e-16
NP_001128327 (OMIM: 606123) E3 ubiquitin-protein l ( 343) 542 85.7 2.1e-16
NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 542 85.9 2.7e-16
NP_439893 (OMIM: 605701) tripartite motif-containi ( 395) 540 85.5 2.8e-16
NP_006769 (OMIM: 605701) tripartite motif-containi ( 481) 540 85.6 3.2e-16
NP_892030 (OMIM: 616017) E3 ubiquitin-protein liga ( 500) 540 85.7 3.3e-16
XP_016856908 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 262) 530 84.0 5.5e-16
XP_016856907 (OMIM: 606123) PREDICTED: E3 ubiquiti ( 262) 530 84.0 5.5e-16
XP_011512533 (OMIM: 613591) PREDICTED: butyrophili ( 313) 511 81.5 3.6e-15
>>NP_003132 (OMIM: 109092) E3 ubiquitin-protein ligase T (475 aa)
initn: 755 init1: 489 opt: 1191 Z-score: 885.8 bits: 173.2 E(85289): 1.3e-42
Smith-Waterman score: 1191; 42.4% identity (68.3% similar) in 458 aa overlap (1-450:1-446)
10 20 30 40 50 60
pF1KB0 MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP
:::.. : ::.:: :::. ...::::.::::.:. ::.. :. .. ::
NP_003 MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGS--------VCP
10 20 30 40 50
70 80 90 100 110
pF1KB0 QCRAPFHMDSLRPNKQLGSLIEALKETDQEMS-------CEEHGEQFHLFCEDEGQLICW
:: : . .::::.::..... ::: .:: : :::..::::: .:. .::
NP_003 VCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 RCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQ
: .. .:. :. . .:.. : :.:::: :. .:.. .. . .. :.. . ::. :.
NP_003 VCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB0 IQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILEL
:...:...: . . :: :::. : .:::.:.. : : . :: :. .:. :. : ::
NP_003 TQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISEL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB0 EEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVS
...:..:: .:::.: .: :: . .:. . .: ::...:.: : :::::. :
NP_003 DRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGL----KKMLRTCAVH
240 250 260 270 280
300 310 320 330 340 350
pF1KB0 VTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDV
.:::::::. :::::::::: : ::.. . .:: ..: ::: . : ::..:.::::
NP_003 ITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDV
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB0 GEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVG
.:::::: ..:.: . .:::::. : .:. : : : : : :::. : ::
NP_003 TGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVG
350 360 370 380 390 400
420 430 440 450 460
pF1KB0 IFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD
::::::::.::::: . : :..: . .:. :::.:
NP_003 IFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIG
410 420 430 440 450 460
NP_003 SQGSTDY
470
>>NP_660215 (OMIM: 607868) E3 ubiquitin-protein ligase T (468 aa)
initn: 1119 init1: 392 opt: 1092 Z-score: 813.9 bits: 159.9 E(85289): 1.4e-38
Smith-Waterman score: 1092; 40.8% identity (63.1% similar) in 463 aa overlap (1-457:1-449)
10 20 30 40 50 60
pF1KB0 MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP
::. . ...:::::.:::. .:.:: .:::..:. :: . .: . . ::
NP_660 MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP------EGPYACP
10 20 30 40 50
70 80 90 100 110
pF1KB0 QCRAPFHMDSLRPNKQLGSLIEALKETDQ-----EMSCEEHGEQFHLFCEDEGQLICWRC
.:: . .::::. :... : .. . : : : . :: :: .:.: :
NP_660 ECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAAC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 ERAPQHKGHTTALVEDVCQGYKEKLQKAVTKL-KQLEDRCTEQKLSTAMRITKWKEKVQI
::. .: .: . ..:. . : ::.:.. .: ::..: : . . :.. :.
NP_660 ERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVL-WQKMVES
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB0 QRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELE
:::.. ..:. :. .: :::.. : :::.:: ..: :::. : :: .: .: : :::
NP_660 QRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB0 EKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSV
.:: : :::...:.: : :::. :.: .::.:.: : : . :: . .:
NP_660 GRCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLV----ETLRRFRGDV
240 250 260 270 280
300 310 320 330 340 350
pF1KB0 TLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVG
:::::::. :::::::::.: :: .. : .:: ::::: : :::::.:.::.::
NP_660 TLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVG
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB0 EGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGI
. :.: :::: :::.: . .::: : . : .: . :.. : :::
NP_660 DRTSWALGVCRENVNRKEKGELSAGNGFWILVFL---GSYYNSSERALAPLRDPPRRVGI
350 360 370 380 390 400
420 430 440 450 460
pF1KB0 FLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD
::::::: .:::... : .: ::. :: :::: :. . ::
NP_660 FLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTICRPKGGSGDTLA
410 420 430 440 450 460
NP_660 PQ
>>XP_016857901 (OMIM: 607868) PREDICTED: E3 ubiquitin-pr (467 aa)
initn: 1130 init1: 340 opt: 1079 Z-score: 804.4 bits: 158.2 E(85289): 4.5e-38
Smith-Waterman score: 1079; 40.8% identity (62.9% similar) in 463 aa overlap (1-457:1-448)
10 20 30 40 50 60
pF1KB0 MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP
::. . ...:::::.:::. .:.:: .:::..:. :: . .: . . ::
XP_016 MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP------EGPYACP
10 20 30 40 50
70 80 90 100 110
pF1KB0 QCRAPFHMDSLRPNKQLGSLIEALKETDQ-----EMSCEEHGEQFHLFCEDEGQLICWRC
.:: . .::::. :... : .. . : : : . :: :: .:.: :
XP_016 ECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAAC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 ERAPQHKGHTTALVEDVCQGYKEKLQKAVTKL-KQLEDRCTEQKLSTAMRITKWKEKVQI
::. .: .: . ..:. . : ::.:.. .: ::..: : . . :. :.
XP_016 ERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVL-WQM-VES
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB0 QRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELE
:::.. ..:. :. .: :::.. : :::.:: ..: :::. : :: .: .: : :::
XP_016 QRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB0 EKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSV
.:: : :::...:.: : :::. :.: .::.:.: : : . :: . .:
XP_016 GRCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLV----ETLRRFRGDV
240 250 260 270 280
300 310 320 330 340 350
pF1KB0 TLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVG
:::::::. :::::::::.: :: .. : .:: ::::: : :::::.:.::.::
XP_016 TLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVG
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB0 EGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGI
. :.: :::: :::.: . .::: : . : .: . :.. : :::
XP_016 DRTSWALGVCRENVNRKEKGELSAGNGFWILVFL---GSYYNSSERALAPLRDPPRRVGI
350 360 370 380 390 400
420 430 440 450 460
pF1KB0 FLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD
::::::: .:::... : .: ::. :: :::: :. . ::
XP_016 FLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTICRPKGGSGDTLA
410 420 430 440 450 460
XP_016 PQ
>>NP_742013 (OMIM: 605700) E3 ubiquitin-protein ligase T (488 aa)
initn: 1127 init1: 400 opt: 1021 Z-score: 762.0 bits: 150.4 E(85289): 1e-35
Smith-Waterman score: 1116; 40.0% identity (65.6% similar) in 483 aa overlap (2-465:11-486)
10 20 30 40
pF1KB0 MASTTSTKKMME----EATCSICLSLMTNPVSINCGHSYCHLCITDFFKNP
::..:: .: ::.::.:: . .:: :.:::..:. ::: ....
NP_742 MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWED-
10 20 30 40 50
50 60 70 80 90 100
pF1KB0 SQKQLRQETFCCPQCRAPFHMDSLRPNKQLGSLIEALKETD-------QEMSCEEHGEQF
:... : :: :: .. :::::.::::..: :. . .: : .: : .
NP_742 ----LERD-FPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEAL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB0 HLFCEDEGQLICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLS
::: .. . .: : . :..::.. ..:. : ::::::: . :.: .. :. : :
NP_742 SLFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB0 TAMRITKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLG
. . :. :. .::.: .:..:. : ::.. : :::.:::. :.:::. : ::
NP_742 EEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLG
180 190 200 210 220 230
230 240 250 260 270
pF1KB0 LKSNELKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELH-TMCNVSKL
: .: :.: :: :. ..:..:..:: . :: .::.::. .. : .
NP_742 DKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQ
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB0 YFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQ-ENQDTSSRRFTAFPCVLG
:: ..:.:.. ..:::::.::: .:.:::::..: :. .. . :::: .::::.
NP_742 YFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLA
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB0 CEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTS
:::::::.:.::.::. : : .::: ..:.: . :..:.: .:: . :.: :.
NP_742 TEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTT
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB0 PPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQV------
: : ::.. .: ::::::::::..:::: . ::.:: .:.. : : :
NP_742 PFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTD-TFTEKLWPLFYPGIRAGR
420 430 440 450 460 470
460
pF1KB0 YQYSPLFLPPPGD
. .:: . :: :
NP_742 KNAAPLTIRPPTDWE
480
>>XP_006711842 (OMIM: 606123) PREDICTED: E3 ubiquitin-pr (477 aa)
initn: 765 init1: 476 opt: 921 Z-score: 689.4 bits: 136.9 E(85289): 1.2e-31
Smith-Waterman score: 921; 34.3% identity (64.6% similar) in 461 aa overlap (1-450:1-456)
10 20 30 40 50
pF1KB0 MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE---TF
: .. ..:..:::::::::. .:.:: .:::..:. :: ... :. :.. .:
XP_006 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 CCPQCRAPFHMDSLRPNKQLGSLIEALKE----TDQEMSCEEHGEQFHLFCEDEGQLICW
::.:: . .: ::. : .. : .. :.. :.:: : ..:::. . . ::
XP_006 PCPECREMSPQRNLLPNRLLTKVAEMAQQHPGLQKQDL-CQEHHEPLKLFCQKDQSPICV
70 80 90 100 110
120 130 140 150 160 170
pF1KB0 RCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQ
:... .:. : . .:.. :::: ::.. . :.. : . . . ...:. ::.
XP_006 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB0 IQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILEL
.:..: .:.... .: :::. : :: ::..: ::::. : : ... :. .:.:
XP_006 ERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB0 EEKCQGSAQKLLQNVNDTLSRSWAVKLETSE-AVSLELHTMCNVSKLYFDVKKMLRSHQV
::. . ..::.... :::. :... : : . .:.: : ..::.
XP_006 EERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQI----EVLRGFLE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB0 SVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSR-RFTAFPCVLGCEGFTSGRRYFEV
.:. : .:. :.: :.:.. : . :.. :. ::.:.::..: .:.:::.:.::
XP_006 DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEV
300 310 320 330 340 350
360 370 380 390 400
pF1KB0 DVG-EGTG-WDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQP
.. : . : :::: .::.: . . :..:::...: : :.. : : . : : :
XP_006 GMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPP
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB0 LLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD
.:::::.::: ::::. . : :. :. .:.: :.:.:
XP_006 SHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVISTVTMWV
420 430 440 450 460 470
XP_006 KG
>>NP_057186 (OMIM: 606123) E3 ubiquitin-protein ligase T (477 aa)
initn: 765 init1: 476 opt: 921 Z-score: 689.4 bits: 136.9 E(85289): 1.2e-31
Smith-Waterman score: 921; 34.3% identity (64.6% similar) in 461 aa overlap (1-450:1-456)
10 20 30 40 50
pF1KB0 MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE---TF
: .. ..:..:::::::::. .:.:: .:::..:. :: ... :. :.. .:
NP_057 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 CCPQCRAPFHMDSLRPNKQLGSLIEALKE----TDQEMSCEEHGEQFHLFCEDEGQLICW
::.:: . .: ::. : .. : .. :.. :.:: : ..:::. . . ::
NP_057 PCPECREMSPQRNLLPNRLLTKVAEMAQQHPGLQKQDL-CQEHHEPLKLFCQKDQSPICV
70 80 90 100 110
120 130 140 150 160 170
pF1KB0 RCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQ
:... .:. : . .:.. :::: ::.. . :.. : . . . ...:. ::.
NP_057 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB0 IQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILEL
.:..: .:.... .: :::. : :: ::..: ::::. : : ... :. .:.:
NP_057 ERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB0 EEKCQGSAQKLLQNVNDTLSRSWAVKLETSE-AVSLELHTMCNVSKLYFDVKKMLRSHQV
::. . ..::.... :::. :... : : . .:.: : ..::.
NP_057 EERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQI----EVLRGFLE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB0 SVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSR-RFTAFPCVLGCEGFTSGRRYFEV
.:. : .:. :.: :.:.. : . :.. :. ::.:.::..: .:.:::.:.::
NP_057 DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEV
300 310 320 330 340 350
360 370 380 390 400
pF1KB0 DVG-EGTG-WDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQP
.. : . : :::: .::.: . . :..:::...: : :.. : : . : : :
NP_057 GMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPP
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB0 LLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD
.:::::.::: ::::. . : :. :. .:.: :.:.:
NP_057 SHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVISTVTMWV
420 430 440 450 460 470
NP_057 KG
>>NP_001020111 (OMIM: 606123) E3 ubiquitin-protein ligas (477 aa)
initn: 765 init1: 476 opt: 921 Z-score: 689.4 bits: 136.9 E(85289): 1.2e-31
Smith-Waterman score: 921; 34.3% identity (64.6% similar) in 461 aa overlap (1-450:1-456)
10 20 30 40 50
pF1KB0 MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE---TF
: .. ..:..:::::::::. .:.:: .:::..:. :: ... :. :.. .:
NP_001 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 CCPQCRAPFHMDSLRPNKQLGSLIEALKE----TDQEMSCEEHGEQFHLFCEDEGQLICW
::.:: . .: ::. : .. : .. :.. :.:: : ..:::. . . ::
NP_001 PCPECREMSPQRNLLPNRLLTKVAEMAQQHPGLQKQDL-CQEHHEPLKLFCQKDQSPICV
70 80 90 100 110
120 130 140 150 160 170
pF1KB0 RCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQ
:... .:. : . .:.. :::: ::.. . :.. : . . . ...:. ::.
NP_001 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB0 IQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILEL
.:..: .:.... .: :::. : :: ::..: ::::. : : ... :. .:.:
NP_001 ERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB0 EEKCQGSAQKLLQNVNDTLSRSWAVKLETSE-AVSLELHTMCNVSKLYFDVKKMLRSHQV
::. . ..::.... :::. :... : : . .:.: : ..::.
NP_001 EERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQI----EVLRGFLE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB0 SVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSR-RFTAFPCVLGCEGFTSGRRYFEV
.:. : .:. :.: :.:.. : . :.. :. ::.:.::..: .:.:::.:.::
NP_001 DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEV
300 310 320 330 340 350
360 370 380 390 400
pF1KB0 DVG-EGTG-WDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQP
.. : . : :::: .::.: . . :..:::...: : :.. : : . : : :
NP_001 GMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPP
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB0 LLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD
.:::::.::: ::::. . : :. :. .:.: :.:.:
NP_001 SHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVISTVTMWV
420 430 440 450 460 470
NP_001 KG
>>XP_011542512 (OMIM: 606123) PREDICTED: E3 ubiquitin-pr (477 aa)
initn: 765 init1: 476 opt: 921 Z-score: 689.4 bits: 136.9 E(85289): 1.2e-31
Smith-Waterman score: 921; 34.3% identity (64.6% similar) in 461 aa overlap (1-450:1-456)
10 20 30 40 50
pF1KB0 MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE---TF
: .. ..:..:::::::::. .:.:: .:::..:. :: ... :. :.. .:
XP_011 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 CCPQCRAPFHMDSLRPNKQLGSLIEALKE----TDQEMSCEEHGEQFHLFCEDEGQLICW
::.:: . .: ::. : .. : .. :.. :.:: : ..:::. . . ::
XP_011 PCPECREMSPQRNLLPNRLLTKVAEMAQQHPGLQKQDL-CQEHHEPLKLFCQKDQSPICV
70 80 90 100 110
120 130 140 150 160 170
pF1KB0 RCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQ
:... .:. : . .:.. :::: ::.. . :.. : . . . ...:. ::.
XP_011 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB0 IQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILEL
.:..: .:.... .: :::. : :: ::..: ::::. : : ... :. .:.:
XP_011 ERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB0 EEKCQGSAQKLLQNVNDTLSRSWAVKLETSE-AVSLELHTMCNVSKLYFDVKKMLRSHQV
::. . ..::.... :::. :... : : . .:.: : ..::.
XP_011 EERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQI----EVLRGFLE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB0 SVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSR-RFTAFPCVLGCEGFTSGRRYFEV
.:. : .:. :.: :.:.. : . :.. :. ::.:.::..: .:.:::.:.::
XP_011 DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEV
300 310 320 330 340 350
360 370 380 390 400
pF1KB0 DVG-EGTG-WDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQP
.. : . : :::: .::.: . . :..:::...: : :.. : : . : : :
XP_011 GMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPP
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB0 LLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD
.:::::.::: ::::. . : :. :. .:.: :.:.:
XP_011 SHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVISTVTMWV
420 430 440 450 460 470
XP_011 KG
>>XP_011542511 (OMIM: 606123) PREDICTED: E3 ubiquitin-pr (477 aa)
initn: 765 init1: 476 opt: 921 Z-score: 689.4 bits: 136.9 E(85289): 1.2e-31
Smith-Waterman score: 921; 34.3% identity (64.6% similar) in 461 aa overlap (1-450:1-456)
10 20 30 40 50
pF1KB0 MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE---TF
: .. ..:..:::::::::. .:.:: .:::..:. :: ... :. :.. .:
XP_011 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 CCPQCRAPFHMDSLRPNKQLGSLIEALKE----TDQEMSCEEHGEQFHLFCEDEGQLICW
::.:: . .: ::. : .. : .. :.. :.:: : ..:::. . . ::
XP_011 PCPECREMSPQRNLLPNRLLTKVAEMAQQHPGLQKQDL-CQEHHEPLKLFCQKDQSPICV
70 80 90 100 110
120 130 140 150 160 170
pF1KB0 RCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQ
:... .:. : . .:.. :::: ::.. . :.. : . . . ...:. ::.
XP_011 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB0 IQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILEL
.:..: .:.... .: :::. : :: ::..: ::::. : : ... :. .:.:
XP_011 ERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB0 EEKCQGSAQKLLQNVNDTLSRSWAVKLETSE-AVSLELHTMCNVSKLYFDVKKMLRSHQV
::. . ..::.... :::. :... : : . .:.: : ..::.
XP_011 EERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQI----EVLRGFLE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB0 SVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSR-RFTAFPCVLGCEGFTSGRRYFEV
.:. : .:. :.: :.:.. : . :.. :. ::.:.::..: .:.:::.:.::
XP_011 DVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEV
300 310 320 330 340 350
360 370 380 390 400
pF1KB0 DVG-EGTG-WDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQP
.. : . : :::: .::.: . . :..:::...: : :.. : : . : : :
XP_011 GMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPP
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB0 LLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD
.:::::.::: ::::. . : :. :. .:.: :.:.:
XP_011 SHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVISTVTMWV
420 430 440 450 460 470
XP_011 KG
>>NP_477514 (OMIM: 607564) tripartite motif-containing p (488 aa)
initn: 1030 init1: 459 opt: 846 Z-score: 634.7 bits: 126.8 E(85289): 1.3e-28
Smith-Waterman score: 1024; 38.3% identity (67.4% similar) in 473 aa overlap (12-450:11-472)
10 20 30 40 50
pF1KB0 MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE-TFCC
::.:: ::: :.:.:.::.::::.:. ::: : .. . :: :
NP_477 MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACIT---PNGRESVIGQEGERSC
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 PQCRAPFHMDSLRPNKQLGSLIEALKET----DQEMS---CEEHGEQFHLFCEDEGQLIC
: :.. .. .::::..:..... :.:. .... : .:::...:::...:..::
NP_477 PVCQTSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVIC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 WRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMR--ITKWKE
: :::. .:.:: : :::.: : :.::.:... :::. :.. .::.. .: :.::.
NP_477 WLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEA--EKLTAFIREKKTSWKN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB0 KVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHI
... .: .:...:..:. .: . :. : .::.::.. : ... : : ... :. :
NP_477 QMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELI
180 190 200 210 220 230
240 250 260 270 280
pF1KB0 LELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLR--
.::..::::...:::.:.:. :: :. ::. .:..: . :.:.:::
NP_477 SDLERRCQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAP----DLKRMLRVC
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB0 -------SHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPC-VLGCE
:. :.:::.: ::. .:.:...:::: .. . . : . : ::: .
NP_477 RELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVR--FVGAKVSGPSCLEKHYDCSVLGSQ
300 310 320 330 340
350 360 370 380
pF1KB0 GFTSGRRYFEVDVGEGTGWDLGVCMENV----------QRGTGM-KQEPQSGFWTLRLCK
:.::..:.::::.. :.: :::: ... : ... . .::::.:.. : .
NP_477 HFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQH
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB0 KKGYVAL--TSPPTSLHLHEQPLLVGIFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTL
.. : : .:: : . : ::.:::::::.::::: : : :.:: : : ::
NP_477 NHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTL
410 420 430 440 450 460
450 460
pF1KB0 RPYFQVYQYSPLFLPPPGD
:::
NP_477 CPYFNPCNCVIPMTLRRPSS
470 480
465 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:44:40 2016 done: Sat Nov 5 17:44:42 2016
Total Scan time: 8.020 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]