FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB0999, 2450 aa 1>>>pF1KB0999 2450 - 2450 aa - 2450 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.9897+/-0.00119; mu= -21.1552+/- 0.072 mean_var=659.9692+/-134.340, 0's: 0 Z-trim(116.4): 54 B-trim: 44 in 1/54 Lambda= 0.049924 statistics sampled from 16965 (17005) to 16965 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.522), width: 16 Scan time: 10.240 The best scores are: opt bits E(32554) CCDS41858.2 NCOR2 gene_id:9612|Hs108|chr12 (2514) 12442 913.0 0 CCDS41857.2 NCOR2 gene_id:9612|Hs108|chr12 (2458) 10933 804.3 0 CCDS55892.1 NCOR2 gene_id:9612|Hs108|chr12 (2504) 10933 804.3 0 CCDS11175.1 NCOR1 gene_id:9611|Hs108|chr17 (2440) 2868 223.4 1.1e-56 CCDS54095.1 NCOR1 gene_id:9611|Hs108|chr17 (2337) 2860 222.8 1.6e-56 CCDS54094.1 NCOR1 gene_id:9611|Hs108|chr17 ( 914) 2566 201.4 1.8e-50 >>CCDS41858.2 NCOR2 gene_id:9612|Hs108|chr12 (2514 aa) initn: 10228 init1: 6903 opt: 12442 Z-score: 4857.7 bits: 913.0 E(32554): 0 Smith-Waterman score: 16081; 96.5% identity (96.5% similar) in 2493 aa overlap (1-2418:1-2482) 10 20 30 40 50 60 pF1KB0 MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB0 LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB0 KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB0 SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB0 DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB0 SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB0 NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB0 AEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB0 EPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB0 EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB0 GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB0 LDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB0 GKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDP :::::::::::::: :::::::::::::::::::::::::::::::::::::: CCDS41 GKSRSPAPPADKEA--------FAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDP 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KB0 SAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQ 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KB0 LHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEA 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KB0 SVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSP 1200 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KB0 SRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYD 1260 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 1380 pF1KB0 MMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLR 1320 1330 1340 1350 1360 1370 1390 1400 1410 1420 1430 1440 pF1KB0 REAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 REAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREE 1380 1390 1400 1410 1420 1430 1450 1460 1470 1480 1490 1500 pF1KB0 LRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDV 1440 1450 1460 1470 1480 1490 1510 1520 1530 1540 1550 1560 pF1KB0 MADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAG 1500 1510 1520 1530 1540 1550 1570 1580 1590 1600 1610 1620 pF1KB0 HLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 HLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYE 1560 1570 1580 1590 1600 1610 1630 1640 1650 1660 1670 1680 pF1KB0 HLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 HLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRG 1620 1630 1640 1650 1660 1670 1690 1700 1710 1720 1730 1740 pF1KB0 YPDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YPDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGII 1680 1690 1700 1710 1720 1730 1750 1760 1770 1780 1790 1800 pF1KB0 DLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTS 1740 1750 1760 1770 1780 1790 1810 1820 1830 1840 1850 1860 pF1KB0 SSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPA ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: CCDS41 SSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSG---GGGGSSSRPA 1800 1810 1820 1830 1840 1870 1880 1890 1900 1910 1920 pF1KB0 SHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAAT 1850 1860 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KB0 FPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 FPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPA 1910 1920 1930 1940 1950 1960 1990 2000 2010 2020 2030 2040 pF1KB0 SSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFS 1970 1980 1990 2000 2010 2020 2050 2060 2070 2080 2090 2100 pF1KB0 IQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 IQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPG 2030 2040 2050 2060 2070 2080 2110 2120 2130 2140 2150 2160 pF1KB0 PVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHP 2090 2100 2110 2120 2130 2140 2170 2180 2190 2200 2210 2220 pF1KB0 QQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKT 2150 2160 2170 2180 2190 2200 2230 2240 2250 2260 2270 2280 pF1KB0 SVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFF 2210 2220 2230 2240 2250 2260 2290 2300 2310 2320 2330 pF1KB0 SKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTG--------- ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAV 2270 2280 2290 2300 2310 2320 pF1KB0 ------------------------------------------------------------ CCDS41 QEHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDH 2330 2340 2350 2360 2370 2380 2340 2350 2360 2370 2380 pF1KB0 ------GGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWED :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TLTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWED 2390 2400 2410 2420 2430 2440 2390 2400 2410 2420 2430 2440 pF1KB0 RPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYET ::::::::::::::::::::::::::::::::: CCDS41 RPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYET 2450 2460 2470 2480 2490 2500 2450 pF1KB0 LSDSE CCDS41 LSDSE 2510 >>CCDS41857.2 NCOR2 gene_id:9612|Hs108|chr12 (2458 aa) initn: 8383 init1: 7544 opt: 10933 Z-score: 4270.5 bits: 804.3 E(32554): 0 Smith-Waterman score: 16306; 97.9% identity (97.9% similar) in 2479 aa overlap (1-2450:1-2458) 10 20 30 40 50 60 pF1KB0 MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSG ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: CCDS41 RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQ-RVGQRGSG 310 320 330 340 350 370 380 390 400 410 420 pF1KB0 LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB0 KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB0 SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB0 DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB0 SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB0 NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB0 AEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP ::: :::::::::::::::::::::::::::::::::::::::: CCDS41 AEA-----------------TVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP 720 730 740 750 760 790 800 810 820 830 840 pF1KB0 EPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG 770 780 790 800 810 820 850 860 870 880 890 900 pF1KB0 EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS 830 840 850 860 870 880 910 920 930 940 950 960 pF1KB0 GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KB0 LDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KB0 GKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDP 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KB0 SAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQ 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KB0 LHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEA 1130 1140 1150 1160 1170 1180 1210 1220 1230 1240 1250 1260 pF1KB0 SVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSP 1190 1200 1210 1220 1230 1240 1270 1280 1290 1300 1310 1320 pF1KB0 SRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYD 1250 1260 1270 1280 1290 1300 1330 1340 1350 1360 1370 1380 pF1KB0 MMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLR 1310 1320 1330 1340 1350 1360 1390 1400 1410 1420 1430 1440 pF1KB0 REAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 REAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREE 1370 1380 1390 1400 1410 1420 1450 1460 1470 1480 1490 1500 pF1KB0 LRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDV 1430 1440 1450 1460 1470 1480 1510 1520 1530 1540 1550 1560 pF1KB0 MADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAG 1490 1500 1510 1520 1530 1540 1570 1580 1590 1600 1610 1620 pF1KB0 HLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 HLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYE 1550 1560 1570 1580 1590 1600 1630 1640 1650 1660 1670 1680 pF1KB0 HLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 HLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRG 1610 1620 1630 1640 1650 1660 1690 1700 1710 1720 1730 1740 pF1KB0 YPDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YPDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGII 1670 1680 1690 1700 1710 1720 1750 1760 1770 1780 1790 1800 pF1KB0 DLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTS 1730 1740 1750 1760 1770 1780 1810 1820 1830 1840 1850 1860 pF1KB0 SSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPA ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: CCDS41 SSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSG---GGGGSSSRPA 1790 1800 1810 1820 1830 1870 1880 1890 1900 1910 1920 pF1KB0 SHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAAT 1840 1850 1860 1870 1880 1890 1930 1940 1950 1960 1970 1980 pF1KB0 FPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 FPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPA 1900 1910 1920 1930 1940 1950 1990 2000 2010 2020 2030 2040 pF1KB0 SSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFS 1960 1970 1980 1990 2000 2010 2050 2060 2070 2080 2090 2100 pF1KB0 IQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 IQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPG 2020 2030 2040 2050 2060 2070 2110 2120 2130 2140 2150 2160 pF1KB0 PVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHP 2080 2090 2100 2110 2120 2130 2170 2180 2190 2200 2210 2220 pF1KB0 QQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKT 2140 2150 2160 2170 2180 2190 2230 2240 2250 2260 2270 2280 pF1KB0 SVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFF 2200 2210 2220 2230 2240 2250 2290 2300 2310 2320 2330 pF1KB0 SKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTG--------- ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAV 2260 2270 2280 2290 2300 2310 2340 2350 2360 2370 pF1KB0 --------------------GGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGD :::::::::::::::::::::::::::::::::::::::: CCDS41 QEHASTNMGLEAIIRKALMGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGD 2320 2330 2340 2350 2360 2370 2380 2390 2400 2410 2420 2430 pF1KB0 CNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 CNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAW 2380 2390 2400 2410 2420 2430 2440 2450 pF1KB0 DEEPKPLLCSQYETLSDSE ::::::::::::::::::: CCDS41 DEEPKPLLCSQYETLSDSE 2440 2450 >>CCDS55892.1 NCOR2 gene_id:9612|Hs108|chr12 (2504 aa) initn: 8389 init1: 7544 opt: 10933 Z-score: 4270.4 bits: 804.3 E(32554): 0 Smith-Waterman score: 15913; 96.1% identity (96.1% similar) in 2485 aa overlap (1-2410:1-2464) 10 20 30 40 50 60 pF1KB0 MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB0 PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPDPLLRP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB0 SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SPLLATGQPAGSEDLTKDRSLTGKLEPVSPPSPPHTDPELELVPPRLSKEELIQNMDRVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB0 REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 REITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRSLVQIIYDENRKKAEA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB0 AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 AHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFKRRNHARKQWEQKFCQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB0 RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQSRVGQRGSG ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: CCDS55 RYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRELQERMQ-RVGQRGSG 310 320 330 340 350 370 380 390 400 410 420 pF1KB0 LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQRIKFINMNGLMADPM 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB0 KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYK 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB0 SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEEKPEVEN 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB0 DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQ 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB0 SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SAELASMELNESSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQ 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB0 NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB0 AEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP ::: :::::::::::::::::::::::::::::::::::::::: CCDS55 AEA-----------------TVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPP 720 730 740 750 760 790 800 810 820 830 840 pF1KB0 EPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG 770 780 790 800 810 820 850 860 870 880 890 900 pF1KB0 EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 EEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS 830 840 850 860 870 880 910 920 930 940 950 960 pF1KB0 GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKP 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KB0 LDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPR 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KB0 GKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDP 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KB0 SAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQ 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KB0 LHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEA 1130 1140 1150 1160 1170 1180 1210 1220 1230 1240 1250 1260 pF1KB0 SVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SVLRGTALGSVPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSP 1190 1200 1210 1220 1230 1240 1270 1280 1290 1300 1310 1320 pF1KB0 SRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SRLDRGREDSLPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYD 1250 1260 1270 1280 1290 1300 1330 1340 1350 1360 1370 1380 pF1KB0 MMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MMEGRVGRAISSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLR 1310 1320 1330 1340 1350 1360 1390 1400 1410 1420 1430 1440 pF1KB0 REAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 REAKLLKREGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREE 1370 1380 1390 1400 1410 1420 1450 1460 1470 1480 1490 1500 pF1KB0 LRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LRHTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDV 1430 1440 1450 1460 1470 1480 1510 1520 1530 1540 1550 1560 pF1KB0 MADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MADARALERACYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAG 1490 1500 1510 1520 1530 1540 1570 1580 1590 1600 1610 1620 pF1KB0 HLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HLPRGSPVTTREPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYE 1550 1560 1570 1580 1590 1600 1630 1640 1650 1660 1670 1680 pF1KB0 HLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRG 1610 1620 1630 1640 1650 1660 1690 1700 1710 1720 1730 1740 pF1KB0 YPDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YPDTAALENRQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRESSLALNYAAGPRGII 1670 1680 1690 1700 1710 1720 1750 1760 1770 1780 1790 1800 pF1KB0 DLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTS 1730 1740 1750 1760 1770 1780 1810 1820 1830 1840 1850 1860 pF1KB0 SSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPA ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: CCDS55 SSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGS---SGGGGGSSSRPA 1790 1800 1810 1820 1830 1870 1880 1890 1900 1910 1920 pF1KB0 SHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SHSHAHQHSPISPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAAT 1840 1850 1860 1870 1880 1890 1930 1940 1950 1960 1970 1980 pF1KB0 FPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPA 1900 1910 1920 1930 1940 1950 1990 2000 2010 2020 2030 2040 pF1KB0 SSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFS 1960 1970 1980 1990 2000 2010 2050 2060 2070 2080 2090 2100 pF1KB0 IQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 IQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPG 2020 2030 2040 2050 2060 2070 2110 2120 2130 2140 2150 2160 pF1KB0 PVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHP 2080 2090 2100 2110 2120 2130 2170 2180 2190 2200 2210 2220 pF1KB0 QQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKT 2140 2150 2160 2170 2180 2190 2230 2240 2250 2260 2270 2280 pF1KB0 SVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFF 2200 2210 2220 2230 2240 2250 2290 2300 2310 2320 2330 pF1KB0 SKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTG--------- ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAV 2260 2270 2280 2290 2300 2310 pF1KB0 ------------------------------------------------------------ CCDS55 QEHASTNMGLEAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDH 2320 2330 2340 2350 2360 2370 2340 2350 2360 2370 2380 pF1KB0 ------GGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWED :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 TLTSPGGGGKAKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWED 2380 2390 2400 2410 2420 2430 2390 2400 2410 2420 2430 2440 pF1KB0 RPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYET ::::::::::::::::::::::::: CCDS55 RPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYET 2440 2450 2460 2470 2480 2490 >>CCDS11175.1 NCOR1 gene_id:9611|Hs108|chr17 (2440 aa) initn: 2280 init1: 1139 opt: 2868 Z-score: 1131.1 bits: 223.4 E(32554): 1.1e-56 Smith-Waterman score: 5071; 40.7% identity (61.4% similar) in 2660 aa overlap (1-2450:1-2439) 10 20 30 40 50 pF1KB0 MSGSTQPVAQTWRATEP-RYPPHSLSYPVQIARTHTDVGLLEYQ--HHSRDYASHLSPGS ::.: : : .:: ::::::..: .: . . .. .:. : . ::.: . CCDS11 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 IIQPQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPD-- : ::::::::::.::..: :: : . . : . . . .:::::::: . : CCDS11 QQQQLRRRPSLLSEFHPGSDRPQER--RTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSH 70 80 90 100 110 120 130 140 150 160 pF1KB0 ---------PLLRPSPLLATGQPAGSEDLTKDRSLTGKLE-PVSPPSPPHTDPELELVPP ::..: : : : : : :: .. :: : : :: : . . : CCDS11 FQRVSAAVLPLVHPLP---EGLRA-SADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB0 RLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRS .::::::::.::::::::. ::::: :::::::::::::::::::::::::::.:.:::: CCDS11 KLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRS 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB0 LVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFK .::::::::::::: ::.:.:::::.::::::::::::. :::::: ::.:::::::.:: CCDS11 IVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFK 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB0 RRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRE :::::::: :::.:::::::::::::::.::::::::.:::::.:::::::::::::::: CCDS11 RRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQRE 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB0 LQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQ :::.: ::::::.::: . ::::::.:::::::::::: :::::::.:::::..::.:. CCDS11 QQERFQ-RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQR 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB0 RIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAE :.::::::::: :::::::::: ::.:...::: :..::.:::::::::::.::::.: . CCDS11 RVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPD 420 430 440 450 460 470 470 480 490 500 510 520 pF1KB0 CVLYYYLTKKNENYKSLVRRSY-RRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKE :::::::::::::::.::::.: .:::..:: . .:... ..... .. . :: :.: CCDS11 CVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEED--KAEKTEKKEEE 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB0 KEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITR :. : ::.:.. :: :: :.: : :. :...:.: .. .::::::::::::::::: CCDS11 KKDEEEKDEKEDSKENTKE---KDKIDGTA-EETEEREQATPRGRKTANSQGRRKGRITR 540 550 560 570 580 590 600 610 620 630 pF1KB0 SMANEAN---------SEEAITP-QQSAELASMELNESSRWTEEEMETAKKGLLEHGRNW ::.::: .:: : : : : :.:::::::::.:::::.:::::: CCDS11 SMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNW 590 600 610 620 630 640 640 650 660 670 680 690 pF1KB0 SAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEA .:::.:::.:. .::::::::::.:.:::..::::: : .. .: .. ..:: . CCDS11 AAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVS 650 660 670 680 690 700 700 710 720 730 740 750 pF1KB0 AFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSP : :::..::: :::: :..:. .. .: ..: .... ..:: :. CCDS11 A----QEDEDIEAS----NEEENPEDSEVEAVKPSE------DSPENATSRGNTE--PAV 710 720 730 740 750 760 770 780 790 800 810 pF1KB0 HTEAAKDTGQNGPKPPATLGADGPPPEPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPS . : . .: .:. .:.. : : : :: . : .... .: : CCDS11 ELEPTTET---APSTSPSLAV------PSTKPAED---ESVETQVNDSISAETAEQMD-- 760 770 780 790 820 830 840 850 860 870 pF1KB0 PSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGP : .:.. :: .. : :::.. .::. : : . . ..: CCDS11 ------VDQQEHSAEEGSVCDP--------PPATKADSVDV---EVRVPENHASKVEGDN 800 810 820 830 840 880 890 900 910 920 930 pF1KB0 AKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDK .: .: . : .: . .. .. .:. .:.:::::::::: ..: .. CCDS11 TKERDLDRASEKVE----PRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEP-ER 850 860 870 880 890 940 950 960 970 980 990 pF1KB0 NRL--LSPRPSLLTPTGDPRANASPQKP--LDLKQLKQRAAAIPPIQVTKVHEPPREDAA .:. .. .::::.:::. .. :: :: ::: ::..:::.:::. : : . CCDS11 QRMFPMDSKPSLLNPTGSILVS-SPLKPNPLDLPQLQHRAAVIPPM----VSCTPCN--- 900 910 920 930 940 1000 1010 1020 1030 1040 1050 pF1KB0 PTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKL : . : . . :. ..:. : : .. CCDS11 ----IPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRS-------------- 950 960 970 980 1060 1070 1080 1090 1100 1110 pF1KB0 PGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTI . :: :: : ::.. .:: .... : : :: :.::. : :: : CCDS11 -STSPCGTS--KSPNREWEVLQPAPH----QVITNLPEGVRLP-----TTRPTRPPPPLI 990 1000 1010 1020 1030 1120 1130 1140 1150 1160 pF1KB0 SNPPPLISSAKHPSVLERQIGAISQG-----MSVQLHVPYSEHAKAP-VGPVTMGLPLPM . ..: : :: . . :.:::: .. . .. :.... : :: ...::: . CCDS11 PSSKTTVASEK-PSFI--MGGSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPRQQ 1040 1050 1060 1070 1080 1090 1170 1180 1190 1200 1210 1220 pF1KB0 DPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPSTR . : : . .:::..:::.: . ::.: : ::. .:.:::: :.. ::::.: :... CCDS11 ESAKSATLPYIKQEEFSPRSQNSQPEGLLV-RAQHEGVVRGTA-GAIQEGSITRGTPTSK 1100 1110 1120 1130 1140 1150 1230 1240 1250 1260 1270 pF1KB0 VPSDSAITYRGSITHGTPA--------DVLYKGTITRIIGEDSPSRLDRGREDSLPKGHV . .: . :::::.:::: ..: ::.:.:. ::: ..:::.. :::: CCDS11 ISVESIPSLRGSITQGTPALPQTGIPTEALVKGSISRMPIEDSSP--EKGREEAASKGHV 1160 1170 1180 1190 1200 1210 1280 1290 1300 1310 1320 1330 pF1KB0 IYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAIS----- :::::.::.:::.. . ..: : : :: . ::.:. .:: . ...: CCDS11 IYEGKSGHILSYDN----IKNARE-GTRSPRTAHEISL-KRSYESVEGNIKQGMSMRESP 1220 1230 1240 1250 1260 1340 1350 1360 1370 1380 pF1KB0 -SASIEGLMGRAIPPERHSPHH-LKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKRE :: .:::. ::.: : ::: :::. . ::: :: ::. .:. :: :. : .::: CCDS11 VSAPLEGLICRALP--RGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYP-KQIKRE 1270 1280 1290 1300 1310 1320 1390 1400 1410 1420 1430 1440 pF1KB0 GTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREEL-----RHT . :: : . : : :: ..: ..:.:: :::::::::... :.: CCDS11 S-----PPIRAFEGAIT-------KGKP-YDG-ITTIKEMGRSIHEIPRQDILTQESRKT 1330 1340 1350 1360 1450 1460 1470 1480 1490 1500 pF1KB0 PELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMADA ::. . ::. ::::.::::.:.:.. : .. ::.:.::: .:.. . ::... . CCDS11 PEVVQSTRPIIEGSISQGTPIKFDNN-SGQSAIKHNVKSLITGPSKLSRGMPPLEIVPEN 1370 1380 1390 1400 1410 1420 1510 1520 1530 1540 1550 pF1KB0 -RALERACYE-----ESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGA-- ...::. :: :...:: .. ::: :. :.. . : : . :: :.: .: CCDS11 IKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRST---LHEAPKAQLSPGIYDDTSARR 1430 1440 1450 1460 1470 1480 1560 1570 1580 1590 1600 1610 pF1KB0 -P--FAGHLPRGSPVTTREPTPRLQEGSLSSSKAS-QDRKLTSTPREIAKSP-HSTVPEH : . . . ::::. .: .. ..::.:.. ..:: : :: . . : .: :: CCDS11 TPVSYQNTMSRGSPMMNRT-----SDVTISSNKSTNHERKSTLTPTQRESIPAKSPVPGV 1490 1500 1510 1520 1530 1620 1630 1640 1650 1660 pF1KB0 HP---HPISPYEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLD-AAAAYYLPRHLAPNP : : ::.. :: .. ..::::.: .:: ..: :: ::::: . :.:.:.: CCDS11 DPVVSH--SPFDPHHRGSTAGEVYRSHLPTHLDP-AMPFHRALDPAAAAYLFQRQLSPTP 1540 1550 1560 1570 1580 1590 1670 1680 1690 1700 1710 1720 pF1KB0 TYPHLYPPYLIRGYPDTAALEN-RQTIINDYITSQQMHHNAATAMAQRADMLRGLSPRES :: : : :.:: ::::.:::::::::. : : :. :::::::. CCDS11 GYPSQYQLY---------AMENTRQTILNDYITSQQMQVNL------RPDVARGLSPREQ 1600 1610 1620 1630 1640 1730 1740 1750 1760 1770 1780 pF1KB0 SLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSR-HSSSPL :.: : : ::::::...: .::: :: . :::..:.: . : : ..:. . CCDS11 PLGLPYPA-TRGIIDLTNMPPT-ILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSASM 1650 1660 1670 1680 1690 1790 1800 1810 1820 1830 1840 pF1KB0 SPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGS ::: ::::. ...:.::::.:.::..:.::: : .... . :::.:: CCDS11 SPGHPTHLA---AAASAEREREREREKERERER---IAAASSDL----YLRPGSEQP--- 1700 1710 1720 1730 1740 1850 1860 1870 1880 1890 1900 pF1KB0 SGSSGGGGGSSSRPASHSHAHQHSPISPRTQDA-LQQRPSVLHNTGMKGIITAVEPSTPT .::.::..... :: : :::.. :::::::...:. ..:: ..:.. CCDS11 -----------GRPGSHGYVRSPSP-SVRTQETMLQQRPSVFQGTNGTSVITPLDPTAQL 1750 1760 1770 1780 1790 1910 1920 1930 1940 1950 pF1KB0 VLRSTSTSSPV----RPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKE----APRVARP . ...: ::. . :. :.. .:.. . . : :: : :. . CCDS11 RIMPLPAGGPSISQGLPASRYNTAADA-LAALVDAAASAPQMDVSKTKESKHEAARLEEN 1800 1810 1820 1830 1840 1850 1960 1970 1980 1990 pF1KB0 ERPR--ADTGHAFLAKPP----ARS--GLEPASS-PSKGSEPRPLV-----------PPV : : : . . : . :: : .:. :: .:. : :: CCDS11 LRSRSAAVSEQQQLEQKTLEVEKRSVQCLYTSSAFPSGKPQPHSSVVYSEAGKDKGPPPK 1860 1870 1880 1890 1900 1910 2000 2010 2020 2030 2040 2050 pF1KB0 SGHATIARTPAKNLAPHHASPDPPAPPASASDPH-REK-TQSKPFSIQELELRSLGYHGS : . :: .:. : ::: ::. .::. : ::. : CCDS11 SRYEEELRTRGKTTITAANFIDVIITRQIASDKDARERGSQSSDSS------SSLSSHRY 1920 1930 1940 1950 1960 2060 2070 2080 2090 2100 2110 pF1KB0 SYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHL ...: .::.:::. ..: . : . .. :.. . :: : : CCDS11 ETPSDAIEVISPASSPAPPQEKLQTYQPEVVKANQAENDPTRQYEGP---------LHHY 1970 1980 1990 2000 2010 2120 2130 2140 2150 2160 pF1KB0 RPLPESQPSSSPLLQTAPGVKGH--------QRVVTLAQHISEVITQDYTRHHPQQLSAP :: .: : :: : :. ... .:..:::.:: ..::::..:.. .. . : CCDS11 RP---QQESPSPQQQLPPSSQAEGMGQVPRTHRLITLADHICQIITQDFARNQVSSQT-P 2020 2030 2040 2050 2060 2070 2170 2180 2190 2200 2210 pF1KB0 LPAPLYSF---PGA--SCPVLDLRRPPSDLYLPPPD-----HGAP-ARGSPH-----SEG : .: :.: : :: : :. : : . : : .: ::. :.: CCDS11 QQPPTSTFQNSPSALVSTPV---RTKTSNRYSPESQAQSVHHQRPGSRVSPENLVDKSRG 2080 2090 2100 2110 2120 2130 2220 2230 2240 2250 2260 2270 pF1KB0 GKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSP .. . :... : . . ::.:::. . : .. :: . : . .: ..:: CCDS11 SRPGKSPERSHV---SSEPYEPISPPQ--VPVVHEKQDSLLLLSQRGAEPAEQRNDARSP 2140 2150 2160 2170 2180 2280 2290 2300 2310 2320 2330 pF1KB0 GNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGT :. : :.::.:: :..: ::::::::: .:::. . .. .. .::::::::.::.: . CCDS11 GSISYLPSFFTKL-ENTSPMVKSKKQEIFRKLNSSGGGDSDMAAAQPGTEIFNLPAVTTS 2190 2200 2210 2220 2230 2240 pF1KB0 GG---------------------------------------------------------- :. CCDS11 GSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKVEDHGVVMSQPMGVVPGTANTSVVTS 2250 2260 2270 2280 2290 2300 2340 2350 2360 2370 pF1KB0 --------------GG--KAKVSGRPSSRKAKSPAPGLA--SGDRPPSVSSVHSEGDCNR :: : :. .. .:::.::: :: . . .:: :::::::::: .: CCDS11 GETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHR 2310 2320 2330 2340 2350 2360 2380 2390 2400 2410 2420 2430 pF1KB0 RTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVMASPPPPGLPAGSG-PLAGPHHA--- .:: . .:::::::.::: :::::: ::. . ..:: : : :. :.::. CCDS11 QTP--GWAWEDRPSSTGSTQFPYNPLTMRMLS---STPPTPIACAPSAVNQAAPHQQNRI 2370 2380 2390 2400 2410 2440 2450 pF1KB0 WDEEPKPLLCSQYETLSDSE :..:: ::: .::::::::. CCDS11 WEREPAPLLSAQYETLSDSDD 2420 2430 2440 >>CCDS54095.1 NCOR1 gene_id:9611|Hs108|chr17 (2337 aa) initn: 2271 init1: 1139 opt: 2860 Z-score: 1128.3 bits: 222.8 E(32554): 1.6e-56 Smith-Waterman score: 5036; 41.1% identity (60.9% similar) in 2625 aa overlap (1-2450:1-2336) 10 20 30 40 50 pF1KB0 MSGSTQPVAQTWRATEP-RYPPHSLSYPVQIARTHTDVGLLEYQ--HHSRDYASHLSPGS ::.: : : .:: ::::::..: .: . . .. .:. : . ::.: . CCDS54 MSSSGYPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQEFAVPDYRSSHLEVSQASQLLQQQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB0 IIQPQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELLPD-- : ::::::::::.::..: :: : . . : . . . .:::::::: . : CCDS54 QQQQLRRRPSLLSEFHPGSDRPQER--RTSYEPFHPGPSPVDHDSLESKRPRLEQVSDSH 70 80 90 100 110 120 130 140 150 160 pF1KB0 ---------PLLRPSPLLATGQPAGSEDLTKDRSLTGKLE-PVSPPSPPHTDPELELVPP ::..: : : : : : :: .. :: : : :: : . . : CCDS54 FQRVSAAVLPLVHPLP---EGLRA-SADAKKDPAFGGKHEAPSSPISGQPCGDDQNASPS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB0 RLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRS .::::::::.::::::::. ::::: :::::::::::::::::::::::::::.:.:::: CCDS54 KLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRS 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB0 LVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFK .::::::::::::: ::.:.:::::.::::::::::::. :::::: ::.:::::::.:: CCDS54 IVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFK 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB0 RRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRE :::::::: :::.:::::::::::::::.::::::::.:::::.:::::::::::::::: CCDS54 RRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQRE 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB0 LQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQ :::.: ::::::.::: . ::::::.:::::::::::: :::::::.:::::..::.:. CCDS54 QQERFQ-RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQR 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB0 RIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAE :.::::::::: :::::::::: ::.:...::: :..::.:::::::::::.::::.: . CCDS54 RVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPD 420 430 440 450 460 470 470 480 490 500 510 520 pF1KB0 CVLYYYLTKKNENYKSLVRRSY-RRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKE :::::::::::::::.::::.: .:::..:: . .:... ..... .. . :: :.: CCDS54 CVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEED--KAEKTEKKEEE 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB0 KEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITR :. : ::.:.. :: :: :.: : :. :...:.: .. .::::::::::::::::: CCDS54 KKDEEEKDEKEDSKENTKE---KDKIDGTA-EETEEREQATPRGRKTANSQGRRKGRITR 540 550 560 570 580 590 600 610 620 630 pF1KB0 SMANEAN---------SEEAITP-QQSAELASMELNESSRWTEEEMETAKKGLLEHGRNW ::.::: .:: : : : : :.:::::::::.:::::.:::::: CCDS54 SMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNW 590 600 610 620 630 640 640 650 660 670 680 690 pF1KB0 SAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEA .:::.:::.:. .::::::::::.:.:::..::::: : .. .: .. ..:: . CCDS54 AAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVS 650 660 670 680 690 700 700 710 720 730 740 750 pF1KB0 AFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSP : :::..::: :::: :..: : : ::::::: ::: CCDS54 A----QEDEDIEAS----NEEENPEDSE-----GAE-------------NSSDTESAPSP 710 720 730 740 760 770 780 790 800 810 pF1KB0 HTEAAKDTGQNGPKPPATLGADGPPPE-PPTPPPEDIPAPTEPTPASE-ATGAPTPPPAP : ....:. .. : : : :: .:. .:... : . . CCDS54 SPVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVN 750 760 770 780 790 800 820 830 840 850 860 870 pF1KB0 PSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEE : :: ...:..: ::: :: : . .:. .: : . . ..: CCDS54 DSISAETAEQMDVDQQEHSA-----EEGSVCDPPPATK--ADSVDVEVRVPENHASKVEG 810 820 830 840 850 880 890 900 910 920 930 pF1KB0 GPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGG .: .: . : .: . .. .. .:. .:.:::::::::: ..: CCDS54 DNTKERDLDRASEKVE----PRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEP- 860 870 880 890 900 940 950 960 970 980 pF1KB0 DKNRL--LSPRPSLLTPTGDPRANASPQKP--LDLKQLKQRAAAIPPIQVTKVHEPPRED ...:. .. .::::.:::. .. :: :: ::: ::..:::.:::. : : . CCDS54 ERQRMFPMDSKPSLLNPTGSILVS-SPLKPNPLDLPQLQHRAAVIPPM----VSCTPCN- 910 920 930 940 950 960 990 1000 1010 1020 1030 1040 pF1KB0 AAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQ : . : . . :. ..:. : : .. CCDS54 ------IPIGTPVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRS------------ 970 980 990 1000 1050 1060 1070 1080 1090 1100 pF1KB0 KLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPP . :: :: : ::.. .:: .... : : :: :.::. : :: CCDS54 ---STSPCGTS--KSPNREWEVLQPAPH----QVITNLPEGVRLP-----TTRPTRPPPP 1010 1020 1030 1040 1050 1110 1120 1130 1140 1150 1160 pF1KB0 TISNPPPLISSAKHPSVLERQIGAISQG-----MSVQLHVPYSEHAKAP-VGPVTMGLPL : . ..: : :: . . :.:::: .. . .. :.... : :: ...::: CCDS54 LIPSSKTTVASEK-PSFI--MGGSISQGTPGTYLTSHNQASYTQETPKPSVGSISLGLPR 1060 1070 1080 1090 1100 1170 1180 1190 1200 1210 1220 pF1KB0 PMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGSVPGGSITKGIPS .. : : . .:::..:::.: . ::.: : ::. .:.:::: :.. ::::.: :. CCDS54 QQESAKSATLPYIKQEEFSPRSQNSQPEGLLV-RAQHEGVVRGTA-GAIQEGSITRGTPT 1110 1120 1130 1140 1150 1160 1230 1240 1250 1260 1270 pF1KB0 TRVPSDSAITYRGSITHGTPA--------DVLYKGTITRIIGEDSPSRLDRGREDSLPKG ... .: . :::::.:::: ..: ::.:.:. ::: ..:::.. :: CCDS54 SKISVESIPSLRGSITQGTPALPQTGIPTEALVKGSISRMPIEDSSP--EKGREEAASKG 1170 1180 1190 1200 1210 1220 1280 1290 1300 1310 1320 1330 pF1KB0 HVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAIS--- :::::::.::.:::.. . ..: : : :: . ::.:. .:: . ...: CCDS54 HVIYEGKSGHILSYDN----IKNARE-GTRSPRTAHEISL-KRSYESVEGNIKQGMSMRE 1230 1240 1250 1260 1270 1340 1350 1360 1370 1380 pF1KB0 ---SASIEGLMGRAIPPERHSPHH-LKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLK :: .:::. ::.: : ::: :::. . ::: :: ::. .:. :: :. : .: CCDS54 SPVSAPLEGLICRALP--RGSPHSDLKERTVLSGSIMQGTPRATTESFEDGLKYP-KQIK 1280 1290 1300 1310 1320 1330 1390 1400 1410 1420 1430 1440 pF1KB0 REGTPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREEL-----R ::. :: : . : : :: ..: ..:.:: :::::::::... : CCDS54 RES-----PPIRAFEGAIT-------KGKP-YDG-ITTIKEMGRSIHEIPRQDILTQESR 1340 1350 1360 1370 1380 1450 1460 1470 1480 1490 1500 pF1KB0 HTPELPLAPRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMA .:::. . ::. ::::.::::.:.:.. : .. ::.:.::: .:.. . ::... CCDS54 KTPEVVQSTRPIIEGSISQGTPIKFDNN-SGQSAIKHNVKSLITGPSKLSRGMPPLEIVP 1390 1400 1410 1420 1430 1440 1510 1520 1530 1540 1550 pF1KB0 DA-RALERACYE-----ESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGA . ...::. :: :...:: .. ::: :. :.. . : : . :: :.: .: CCDS54 ENIKVVERGKYEDVKAGETVRSRHTSVVSSGPSVLRST---LHEAPKAQLSPGIYDDTSA 1450 1460 1470 1480 1490 1560 1570 1580 1590 1600 pF1KB0 ---P--FAGHLPRGSPVTTREPTPRLQEGSLSSSKAS-QDRKLTSTPREIAKSP-HSTVP : . . . ::::. .: .. ..::.:.. ..:: : :: . . : .: :: CCDS54 RRTPVSYQNTMSRGSPMMNRT-----SDVTISSNKSTNHERKSTLTPTQRESIPAKSPVP 1500 1510 1520 1530 1540 1550 1610 1620 1630 1640 1650 1660 pF1KB0 EHHP---HPISPYEHLLRGVSGVDLYRSHIPLAFDPTSIPRGIPLD-AAAAYYLPRHLAP : : ::.. :: .. ..::::.: .:: ..: :: ::::: . :.:.: CCDS54 GVDPVVSH--SPFDPHHRGSTAGEVYRSHLPTHLDP-AMPFHRALDPAAAAYLFQRQLSP 1560 1570 1580 1590 1600 1670 1680 1690 1700 1710 1720 pF1KB0 NPTYPHLYPPYLIRGYPDTAALEN-RQTIINDYITSQQMHHNAATAMAQRADMLRGLSPR .: :: : : :.:: ::::.:::::::::. : : :. :::::: CCDS54 TPGYPSQYQLY---------AMENTRQTILNDYITSQQMQVNL------RPDVARGLSPR 1610 1620 1630 1640 1650 1730 1740 1750 1760 1770 1780 pF1KB0 ESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSR-HSSS :. :.: : : ::::::...: .::: :: . :::..:.: . : : ..:. CCDS54 EQPLGLPYPA-TRGIIDLTNMPPT-ILVPHPGGTSTPPMDRITYIPGTQITFPPRPYNSA 1660 1670 1680 1690 1700 1710 1790 1800 1810 1820 1830 1840 pF1KB0 PLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSS .::: ::::. ...:.::::.:.::..:.::: : .... . :::.:: CCDS54 SMSPGHPTHLA---AAASAEREREREREKERERER---IAAASSDL----YLRPGSEQ-- 1720 1730 1740 1750 1760 1850 1860 1870 1880 1890 1900 pF1KB0 GSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDA-LQQRPSVLHNTGMKGIITAVEPST .::.::..... :: : :::.. :::::::...:. ..:: ..:.. CCDS54 ------------PGRPGSHGYVRSPSP-SVRTQETMLQQRPSVFQGTNGTSVITPLDPTA 1770 1780 1790 1800 1910 1920 1930 1940 1950 1960 pF1KB0 PTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRVARPERPRAD :: . : : :: :.. . :: : . CCDS54 Q--LR-------IMPL---------PAGG------PSISQG--LPAS----------RYN 1810 1820 1830 1970 1980 1990 2000 2010 2020 pF1KB0 TGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASP-DPPA :. :: .. : . :: .: .:.: .::. : . :: . :: CCDS54 TAADALAALVDAAASAPQMDVSKTKE-------ISSHRY--ETPSD--AIEVISPASSPA 1840 1850 1860 1870 1880 2030 2040 2050 2060 2070 2080 pF1KB0 PPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLTHDKGLPKH :: .:: :. :.:: :. . ..:. .. : : CCDS54 PP-------QEKLQT-------------------YQPEVVKANQAENDPTRQYEG--PLH 1890 1900 1910 2090 2100 2110 2120 2130 2140 pF1KB0 LEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVV : ::.: .: . .:: : :: . . .: . : :.. CCDS54 -------HY----RPQQESP----SPQQQLP-----PSSQAEG---MGQVP--RTH-RLI 1920 1930 1940 2150 2160 2170 2180 2190 pF1KB0 TLAQHISEVITQDYTRHHPQQLSAPLPAPLYSF---PGA--SCPVLDLRRPPSDLYLPPP :::.:: ..::::..:.. .. . : : .: :.: : :: : :. : : CCDS54 TLADHICQIITQDFARNQVSSQT-PQQPPTSTFQNSPSALVSTPV---RTKTSNRYSPES 1950 1960 1970 1980 1990 2000 2200 2210 2220 2230 2240 pF1KB0 D-----HGAP-ARGSPH-----SEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHS . : : .: ::. :.:.. . :... : . . ::.:::. . : CCDS54 QAQSVHHQRPGSRVSPENLVDKSRGSRPGKSPERSHV---SSEPYEPISPPQ--VPVVHE 2010 2020 2030 2040 2050 2250 2260 2270 2280 2290 2300 pF1KB0 RSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTH .. :: . : . .: ..:::. : :.::.:: :..: ::::::::: .:::. CCDS54 KQDSLLLLSQRGAEPAEQRNDARSPGSISYLPSFFTKL-ENTSPMVKSKKQEIFRKLNSS 2060 2070 2080 2090 2100 2110 2310 2320 2330 pF1KB0 NRNEPEYNISQPGTEIFNMPAITGTGG--------------------------------- . .. .. .::::::::.::.: .:. CCDS54 GGGDSDMAAAQPGTEIFNLPAVTTSGSVSSRGHSFADPASNLGLEDIIRKALMGSFDDKV 2120 2130 2140 2150 2160 2170 2340 2350 pF1KB0 ---------------------------------------GG--KAKVSGRPSSRKAKSPA :: : :. .. .:::.::: CCDS54 EDHGVVMSQPMGVVPGTANTSVVTSGETRREEGDPSPHSGGVCKPKLISKSNSRKSKSPI 2180 2190 2200 2210 2220 2230 2360 2370 2380 2390 2400 pF1KB0 PGLA--SGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRLQAGVM :: . . .:: :::::::::: .:.:: . .:::::::.::: :::::: ::. . CCDS54 PGQGYLGTERPSSVSSVHSEGDYHRQTP--GWAWEDRPSSTGSTQFPYNPLTMRMLS--- 2240 2250 2260 2270 2280 2290 2410 2420 2430 2440 2450 pF1KB0 ASPPPPGLPAGSG-PLAGPHHA---WDEEPKPLLCSQYETLSDSE ..:: : : :. :.::. :..:: ::: .::::::::. CCDS54 STPPTPIACAPSAVNQAAPHQQNRIWEREPAPLLSAQYETLSDSDD 2300 2310 2320 2330 >>CCDS54094.1 NCOR1 gene_id:9611|Hs108|chr17 (914 aa) initn: 1665 init1: 1139 opt: 2566 Z-score: 1019.7 bits: 201.4 E(32554): 1.8e-50 Smith-Waterman score: 2780; 52.9% identity (71.1% similar) in 918 aa overlap (137-1026:36-907) 110 120 130 140 150 160 pF1KB0 RPRLELLPDPLLRPSPLLATGQPAGSEDLTKDRSLTGKLE-PVSPPSPPHTDPELELVPP .: .. :: : : :: : . . : CCDS54 YPPNQGAFSTEQSRYPPHSVQYTFPNTRHQQDPAFGGKHEAPSSPISGQPCGDDQNASPS 10 20 30 40 50 60 170 180 190 200 210 220 pF1KB0 RLSKEELIQNMDRVDREITMVEQQISKLKKKQQQLEEEAAKPPEPEKPVSPPPIESKHRS .::::::::.::::::::. ::::: :::::::::::::::::::::::::::.:.:::: CCDS54 KLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPEKPVSPPPVEQKHRS 70 80 90 100 110 120 230 240 250 260 270 280 pF1KB0 LVQIIYDENRKKAEAAHRILEGLGPQVELPLYNQPSDTRQYHENIKINQAMRKKLILYFK .::::::::::::: ::.:.:::::.::::::::::::. :::::: ::.:::::::.:: CCDS54 IVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFK 130 140 150 160 170 180 290 300 310 320 330 340 pF1KB0 RRNHARKQWEQKFCQRYDQLMEAWEKKVERIENNPRRRAKESKVREYYEKQFPEIRKQRE :::::::: :::.:::::::::::::::.::::::::.:::::.:::::::::::::::: CCDS54 RRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQRE 190 200 210 220 230 240 350 360 370 380 390 400 pF1KB0 LQERMQSRVGQRGSGLSMSAARSEHEVSEIIDGLSEQENLEKQMRQLAVIPPMLYDADQQ :::.: ::::::.::: . ::::::.:::::::::::: :::::::.:::::..::.:. CCDS54 QQERFQ-RVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQR 250 260 270 280 290 300 410 420 430 440 450 460 pF1KB0 RIKFINMNGLMADPMKVYKDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAE :.::::::::: :::::::::: ::.:...::: :..::.:::::::::::.::::.: . CCDS54 RVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPD 310 320 330 340 350 360 470 480 490 500 510 520 pF1KB0 CVLYYYLTKKNENYKSLVRRSY-RRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKE :::::::::::::::.::::.: .:::..:: . .:... ..... .. . :: :.: CCDS54 CVLYYYLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEED--KAEKTEKKEEE 370 380 390 400 410 420 530 540 550 560 570 580 pF1KB0 KEKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITR :. : ::.:.. :: :: :.: : :. :...:.: .. .::::::::::::::::: CCDS54 KKDEEEKDEKEDSKENTKE---KDKIDGTA-EETEEREQATPRGRKTANSQGRRKGRITR 430 440 450 460 470 590 600 610 620 630 pF1KB0 SMANEAN---------SEEAITP-QQSAELASMELNESSRWTEEEMETAKKGLLEHGRNW ::.::: .:: : : : : :.:::::::::.:::::.:::::: CCDS54 SMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNW 480 490 500 510 520 530 640 650 660 670 680 690 pF1KB0 SAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEA .:::.:::.:. .::::::::::.:.:::..::::: : .. .: .. ..:: . CCDS54 AAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVS 540 550 560 570 580 590 700 710 720 730 740 750 pF1KB0 AFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSP : :::..::: :::: :..: : : ::::::: ::: CCDS54 A----QEDEDIEAS----NEEENPEDSE-----GAE-------------NSSDTESAPSP 600 610 620 630 760 770 780 790 800 810 pF1KB0 HTEAAKDTGQNGPKPPATLGADGPPPE-PPTPPPEDIPAPTEPTPASE-ATGAPTPPPAP : ....:. .. : : : :: .:. .:... : . . CCDS54 SPVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVN 640 650 660 670 680 690 820 830 840 850 860 870 pF1KB0 PSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEE : :: ...:..: ::: :: : . .:. .: : . . ..: CCDS54 DSISAETAEQMDVDQQEHSA-----EEGSVCDPPPATK--ADSVDVEVRVPENHASKVEG 700 710 720 730 740 880 890 900 910 920 930 pF1KB0 GPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGG .: .: . : .: . .. .. .:. .:.:::::::::: ..: CCDS54 DNTKERDLDRASEKVE----PRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEP- 750 760 770 780 790 800 940 950 960 970 980 pF1KB0 DKNRL--LSPRPSLLTPTGDPRANASPQKP--LDLKQLKQRAAAIPP-IQVTKVHEP--- ...:. .. .::::.:::. .. :: :: ::: ::..:::.::: .. : . : CCDS54 ERQRMFPMDSKPSLLNPTGSILVS-SPLKPNPLDLPQLQHRAAVIPPMVSCTPCNIPIGT 810 820 830 840 850 990 1000 1010 1020 1030 pF1KB0 PREDAAPTKPAPPAPPPPQNLQPESDAPQQ------PGSSPRGKSRSPAPPADKEAEKPV : : . : :. . . .: ..:: : :.:: CCDS54 PVSGYALYQRHIKAMHESALLEEQRQRQEQIDLECRSSTSPCGTSKSPNREWEGR 860 870 880 890 900 910 1040 1050 1060 1070 1080 1090 pF1KB0 FFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHD 2450 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:41:27 2016 done: Sat Nov 5 01:41:29 2016 Total Scan time: 10.240 Total Display time: 1.350 Function used was FASTA [36.3.4 Apr, 2011]