FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB1292, 652 aa 1>>>pF1KB1292 652 - 652 aa - 652 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9245+/-0.00107; mu= 16.8635+/- 0.064 mean_var=82.6423+/-16.547, 0's: 0 Z-trim(104.8): 15 B-trim: 181 in 2/46 Lambda= 0.141082 statistics sampled from 8100 (8105) to 8100 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.249), width: 16 Scan time: 2.810 The best scores are: opt bits E(32554) CCDS6132.1 SLC20A2 gene_id:6575|Hs108|chr8 ( 652) 4273 880.0 0 CCDS2099.1 SLC20A1 gene_id:6574|Hs108|chr2 ( 679) 1240 262.7 1.2e-69 >>CCDS6132.1 SLC20A2 gene_id:6575|Hs108|chr8 (652 aa) initn: 4273 init1: 4273 opt: 4273 Z-score: 4700.4 bits: 880.0 E(32554): 0 Smith-Waterman score: 4273; 99.8% identity (100.0% similar) in 652 aa overlap (1-652:1-652) 10 20 30 40 50 60 pF1KB1 MAMDEYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 MAMDEYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 LLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIASFLRLPISGTHCIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 LLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIASFLRLPISGTHCIVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 STIGFSLVAIGTKGVQWMELVKIVASWFISPLLSGFMSGLLFVLIRIFILKKEDPVPNGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 STIGFSLVAIGTKGVQWMELVKIVASWFISPLLSGFMSGLLFVLIRIFILKKEDPVPNGL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 RALPVFYAATIAINVFSIMYTGAPVLGLVLPMWAIALISFGVALLFAFFVWLFVCPWMRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 RALPVFYAATIAINVFSIMYTGAPVLGLVLPMWAIALISFGVALLFAFFVWLFVCPWMRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 KITGKLQKEGALSRVSDESLSKVQEAESPVFKELPGAKANDDSTIPLTGAAGETLGTSEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 KITGKLQKEGALSRVSDESLSKVQEAESPVFKELPGAKANDDSTIPLTGAAGETLGTSEG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 TSASSHPRAAYGRALSMTHGSVKSPISNGTFGFDGHTRSDGHVYHTVHKDSGLYKDLLHK :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 TSAGSHPRAAYGRALSMTHGSVKSPISNGTFGFDGHTRSDGHVYHTVHKDSGLYKDLLHK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 IHIDRGPEEKPAQESNYRLLRRNNSYTCYTAAICGLPVHATFRAADSSAPEDSEKLVGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 IHIDRGPEEKPAQESNYRLLRRNNSYTCYTAAICGLPVHATFRAADSSAPEDSEKLVGDT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 VSYSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMKLASELADPDQPREDPAEEEKEEKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 VSYSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMKLASELADPDQPREDPAEEEKEEKDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 PEVHLLFHFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYKQGGVTQEAATPVWLLFYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 PEVHLLFHFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYKQGGVTQEAATPVWLLFYG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 GVGICTGLWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 GVGICTGLWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVG 550 560 570 580 590 600 610 620 630 640 650 pF1KB1 SVVAVGWIRSRKAVDWRLFRNIFVAWFVTVPVAGLFSAAVMALLMYGILPYV :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 SVVAVGWIRSRKAVDWRLFRNIFVAWFVTVPVAGLFSAAVMALLMYGILPYV 610 620 630 640 650 >>CCDS2099.1 SLC20A1 gene_id:6574|Hs108|chr2 (679 aa) initn: 2430 init1: 1096 opt: 1240 Z-score: 1363.8 bits: 262.7 E(32554): 1.2e-69 Smith-Waterman score: 2523; 60.7% identity (80.1% similar) in 672 aa overlap (5-649:20-677) 10 20 30 40 pF1KB1 MAMDEYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLR .::::.::::::::.:::::::::::::::::::::::::. CCDS20 MATLITSTTAATAASGPLVDYLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLK 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB1 QACILASIFETTGSVLLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIA :::::::::::.:::::::::.::::::.:::..:: : :::: :::: :::::::.: CCDS20 QACILASIFETVGSVLLGAKVSETIRKGLIDVEMYNSTQGLLMAGSVSAMFGSAVWQLVA 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB1 SFLRLPISGTHCIVGSTIGFSLVAIGTKGVQWMELVKIVASWFISPLLSGFMSGLLFVLI :::.:::::::::::.:::::::: : .::.: ::.::: :::.::::::.:::.:: :. CCDS20 SFLKLPISGTHCIVGATIGFSLVAKGQEGVKWSELIKIVMSWFVSPLLSGIMSGILFFLV 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB1 RIFILKKEDPVPNGLRALPVFYAATIAINVFSIMYTGAPVLGL-VLPMWAIALISFGVAL : :::.: ::::::::::::::: :..::.:::::::::.::. ::.:. ::: : :. CCDS20 RAFILHKADPVPNGLRALPVFYACTVGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAV 190 200 210 220 230 240 230 240 250 260 270 pF1KB1 LFAFFVWLFVCPWMRRKITGK----------LQKEGALSRVSDESLSKVQEAES--PVFK . :..::.:::: :.::: . ..:...:.. .:. .: . :. :: . CCDS20 FCALIVWFFVCPRMKRKIEREIKCSPSESPLMEKKNSLKEDHEETKLSVGDIENKHPVSE 250 260 270 280 290 300 280 290 300 310 320 pF1KB1 ELPGAKANDDSTIPLTGAAGET-----LGTSEGTSASSH-PRAAYGRALSM---THGSVK : .:.:: ... : :: : . . : . . :. ..:.:. CCDS20 VGP-------ATVPLQAVVEERTVSFKLGDLEEAPERERLPSVDLKEETSIDSTVNGAVQ 310 320 330 340 350 330 340 350 360 370 pF1KB1 SPISNGT-FG--FDGHTRSDGHV-YHTVHKDSGLYKDLLHKIHIDRGPEEKPAQESNYRL : .: . :. ... :.:: ::::::::::::.::::.:. . . .:. . CCDS20 LPNGNLVQFSQAVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDC--MGDSGDKP 360 370 380 390 400 410 380 390 400 410 420 430 pF1KB1 LRRNNSYTCYTAAICGLPVHATFRAADSSAP-EDSEKLVGDTVSYSKKRLRYDSYSSYCN :::::::: :: ::::.:. .::: .. :. :::. ... ::::.:.:::.:::: CCDS20 LRRNNSYTSYTMAICGMPLD-SFRAKEGEQKGEEMEKLTWPNAD-SKKRIRMDSYTSYCN 420 430 440 450 460 440 450 460 470 480 490 pF1KB1 AVAEAEIEAEEGGVEMKLASELADPDQPREDPAEEEKEEKDAPEVHLLFHFLQVLTACFG ::.. . .: ..:.. .:.. :. . . :: ..: ::: :::.:::.:::::: CCDS20 AVSDLHSASE---IDMSVKAEMGLGDRKGSNGSLEEWYDQDKPEVSLLFQFLQILTACFG 470 480 490 500 510 520 500 510 520 530 540 550 pF1KB1 SFAHGGNDVSNAIGPLVALWLIYKQGGVTQEAATPVWLLFYGGVGICTGLWVWGRRVIQT :::::::::::::::::::.:.: : :....:::.:::.:::::::.:::::::::::: CCDS20 SFAHGGNDVSNAIGPLVALYLVYDTGDVSSKVATPIWLLLYGGVGICVGLWVWGRRVIQT 530 540 550 560 570 580 560 570 580 590 600 610 pF1KB1 MGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGWIRSRKAVDWRL ::::::::::::::.::::::.:::::::::::.:::::::::::.:::.::.::::::: CCDS20 MGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRL 590 600 610 620 630 640 620 630 640 650 pF1KB1 FRNIFVAWFVTVPVAGLFSAAVMALLMYGILPYV :::::.:::::::..:..:::.::.. : :: CCDS20 FRNIFMAWFVTVPISGVISAAIMAIFRYVILRM 650 660 670 652 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:24:06 2016 done: Thu Nov 3 20:24:07 2016 Total Scan time: 2.810 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]