FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB1326, 942 aa 1>>>pF1KB1326 942 - 942 aa - 942 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4174+/-0.000404; mu= 8.2200+/- 0.025 mean_var=219.2983+/-45.225, 0's: 0 Z-trim(120.1): 170 B-trim: 63 in 1/50 Lambda= 0.086608 statistics sampled from 34629 (34828) to 34629 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.408), width: 16 Scan time: 15.290 The best scores are: opt bits E(85289) NP_001338 (OMIM: 601207) diacylglycerol kinase the ( 942) 6516 827.8 0 XP_011511713 (OMIM: 601207) PREDICTED: diacylglyce ( 942) 6168 784.3 0 XP_011511714 (OMIM: 601207) PREDICTED: diacylglyce ( 630) 4404 563.8 9.8e-160 XP_016863303 (OMIM: 601207) PREDICTED: diacylglyce ( 597) 4059 520.6 9e-147 XP_011511716 (OMIM: 601207) PREDICTED: diacylglyce ( 583) 4036 517.8 6.4e-146 XP_011511717 (OMIM: 601207) PREDICTED: diacylglyce ( 486) 3426 441.5 5e-123 XP_016863304 (OMIM: 601207) PREDICTED: diacylglyce ( 481) 3395 437.6 7.2e-122 NP_003638 (OMIM: 601440,615008) diacylglycerol kin ( 567) 871 122.3 7e-27 XP_011523696 (OMIM: 601440,615008) PREDICTED: diac ( 585) 871 122.3 7.2e-27 XP_011518725 (OMIM: 601441) PREDICTED: diacylglyce ( 809) 832 117.6 2.7e-25 NP_001186197 (OMIM: 601441) diacylglycerol kinase ( 906) 832 117.6 2.9e-25 XP_011518724 (OMIM: 601441) PREDICTED: diacylglyce ( 911) 832 117.6 2.9e-25 NP_001186196 (OMIM: 601441) diacylglycerol kinase ( 928) 832 117.6 2.9e-25 NP_003637 (OMIM: 601441) diacylglycerol kinase zet ( 929) 832 117.6 3e-25 NP_963291 (OMIM: 601441) diacylglycerol kinase zet ( 933) 832 117.6 3e-25 XP_006718418 (OMIM: 601441) PREDICTED: diacylglyce ( 933) 832 117.6 3e-25 XP_005253239 (OMIM: 601441) PREDICTED: diacylglyce ( 934) 832 117.6 3e-25 NP_001186195 (OMIM: 601441) diacylglycerol kinase ( 934) 832 117.6 3e-25 NP_963290 (OMIM: 601441) diacylglycerol kinase zet ( 945) 832 117.6 3e-25 XP_005253238 (OMIM: 601441) PREDICTED: diacylglyce ( 946) 832 117.6 3e-25 NP_001099010 (OMIM: 601441) diacylglycerol kinase (1117) 832 117.7 3.4e-25 XP_006718417 (OMIM: 601441) PREDICTED: diacylglyce (1118) 832 117.7 3.4e-25 XP_016873946 (OMIM: 601441) PREDICTED: diacylglyce (1153) 832 117.7 3.5e-25 XP_016873945 (OMIM: 601441) PREDICTED: diacylglyce (1175) 832 117.7 3.5e-25 XP_016873944 (OMIM: 601441) PREDICTED: diacylglyce (1176) 832 117.7 3.5e-25 XP_011523697 (OMIM: 601440,615008) PREDICTED: diac ( 543) 788 111.9 9e-24 XP_011514986 (OMIM: 604072) PREDICTED: diacylglyce ( 724) 781 111.1 2e-23 NP_001308639 (OMIM: 604072) diacylglycerol kinase ( 734) 781 111.1 2.1e-23 XP_016868277 (OMIM: 604072) PREDICTED: diacylglyce ( 757) 781 111.2 2.1e-23 NP_001308638 (OMIM: 604072) diacylglycerol kinase ( 757) 781 111.2 2.1e-23 XP_016868275 (OMIM: 604072) PREDICTED: diacylglyce ( 778) 781 111.2 2.1e-23 XP_016868276 (OMIM: 604072) PREDICTED: diacylglyce ( 778) 781 111.2 2.1e-23 XP_016868274 (OMIM: 604072) PREDICTED: diacylglyce ( 879) 781 111.2 2.3e-23 XP_011514984 (OMIM: 604072) PREDICTED: diacylglyce ( 946) 781 111.2 2.5e-23 XP_016868273 (OMIM: 604072) PREDICTED: diacylglyce ( 963) 781 111.2 2.5e-23 XP_016868272 (OMIM: 604072) PREDICTED: diacylglyce ( 985) 781 111.3 2.6e-23 XP_016868270 (OMIM: 604072) PREDICTED: diacylglyce (1021) 781 111.3 2.6e-23 NP_001308637 (OMIM: 604072) diacylglycerol kinase (1057) 781 111.3 2.7e-23 NP_004708 (OMIM: 604072) diacylglycerol kinase iot (1065) 781 111.3 2.7e-23 XP_016868269 (OMIM: 604072) PREDICTED: diacylglyce (1078) 781 111.3 2.7e-23 XP_016880732 (OMIM: 601440,615008) PREDICTED: diac ( 691) 629 92.1 1e-17 XP_016867279 (OMIM: 604070) PREDICTED: diacylglyce ( 725) 584 86.5 5.2e-16 NP_663733 (OMIM: 604070) diacylglycerol kinase bet ( 773) 584 86.5 5.5e-16 XP_011513460 (OMIM: 604070) PREDICTED: diacylglyce ( 785) 584 86.6 5.6e-16 XP_005249688 (OMIM: 604070) PREDICTED: diacylglyce ( 785) 584 86.6 5.6e-16 XP_016867278 (OMIM: 604070) PREDICTED: diacylglyce ( 792) 584 86.6 5.6e-16 XP_016867277 (OMIM: 604070) PREDICTED: diacylglyce ( 792) 584 86.6 5.6e-16 XP_011513459 (OMIM: 604070) PREDICTED: diacylglyce ( 792) 584 86.6 5.6e-16 XP_011513458 (OMIM: 604070) PREDICTED: diacylglyce ( 796) 584 86.6 5.6e-16 XP_016867275 (OMIM: 604070) PREDICTED: diacylglyce ( 796) 584 86.6 5.6e-16 >>NP_001338 (OMIM: 601207) diacylglycerol kinase theta [ (942 aa) initn: 6516 init1: 6516 opt: 6516 Z-score: 4412.6 bits: 827.8 E(85289): 0 Smith-Waterman score: 6516; 99.9% identity (100.0% similar) in 942 aa overlap (1-942:1-942) 10 20 30 40 50 60 pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEET 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 RYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLSVDEADAVLMDRWTILLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLSVDEADAVLMDRWTILLD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 AHEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB1 RVGLQKISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRFEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVGLQKISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRFEKP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB1 RMDDGLLEVVGVTGVVYMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWVQAPGH ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 RMDDGLLEVVGVTGVVHMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWVQAPGH 850 860 870 880 890 900 910 920 930 940 pF1KB1 MIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR :::::::::::::::::::::::::::::::::::::::::: NP_001 MIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR 910 920 930 940 >>XP_011511713 (OMIM: 601207) PREDICTED: diacylglycerol (942 aa) initn: 6133 init1: 6133 opt: 6168 Z-score: 4177.6 bits: 784.3 E(85289): 0 Smith-Waterman score: 6168; 95.3% identity (96.6% similar) in 945 aa overlap (1-942:1-942) 10 20 30 40 50 60 pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ... XP_011 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQGGLE 430 440 450 460 470 480 490 500 510 520 530 pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLP--P-GLSPEEYSSLLHEAGATKATVVSVSHIYS . : . .: :. . . : .: : : : . : : ::::::::::: XP_011 LQISPRSSRGTDRGC-PQQGSLCGPFPRFPVDLIPGSVPDALFCCFA--ATVVSVSHIYS 490 500 510 520 530 540 550 560 570 580 590 pF1KB1 SQGAVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQGAVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKS 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB1 GGLKGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGLKGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGAL 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB1 EETRYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLSVDEADAVLMDRWTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EETRYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLSVDEADAVLMDRWTI 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB1 LLDAHEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLDAHEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKG 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB1 VYVRVGLQKISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYVRVGLQKISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRF 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB1 EKPRMDDGLLEVVGVTGVVYMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWVQA :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: XP_011 EKPRMDDGLLEVVGVTGVVHMGQVQGGLRSGIRIAQGSYFRVTLLKATPVQVDGEPWVQA 840 850 860 870 880 890 900 910 920 930 940 pF1KB1 PGHMIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR ::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGHMIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR 900 910 920 930 940 >>XP_011511714 (OMIM: 601207) PREDICTED: diacylglycerol (630 aa) initn: 4404 init1: 4404 opt: 4404 Z-score: 2988.7 bits: 563.8 E(85289): 9.8e-160 Smith-Waterman score: 4404; 100.0% identity (100.0% similar) in 629 aa overlap (1-629:1-629) 10 20 30 40 50 60 pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEET ::::::::::::::::::::::::::::: XP_011 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGE 610 620 630 >>XP_016863303 (OMIM: 601207) PREDICTED: diacylglycerol (597 aa) initn: 4059 init1: 4059 opt: 4059 Z-score: 2756.1 bits: 520.6 E(85289): 9e-147 Smith-Waterman score: 4059; 99.0% identity (99.0% similar) in 588 aa overlap (1-588:1-588) 10 20 30 40 50 60 pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL :::::::::::::::::::::::::::::::::::::: : ::: XP_016 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLLPALGTRSCPQTAVPSLCS 550 560 570 580 590 610 620 630 640 650 660 pF1KB1 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEET >>XP_011511716 (OMIM: 601207) PREDICTED: diacylglycerol (583 aa) initn: 4036 init1: 4036 opt: 4036 Z-score: 2740.7 bits: 517.8 E(85289): 6.4e-146 Smith-Waterman score: 4036; 100.0% identity (100.0% similar) in 578 aa overlap (1-578:1-578) 10 20 30 40 50 60 pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGL :::::::::::::::::::::::::::::::::::::: XP_011 AVVLDVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLLPALG 550 560 570 580 610 620 630 640 650 660 pF1KB1 KGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEET >>XP_011511717 (OMIM: 601207) PREDICTED: diacylglycerol (486 aa) initn: 3426 init1: 3426 opt: 3426 Z-score: 2329.8 bits: 441.5 E(85289): 5e-123 Smith-Waterman score: 3426; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481) 10 20 30 40 50 60 pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG : XP_011 QPPWCP >>XP_016863304 (OMIM: 601207) PREDICTED: diacylglycerol (481 aa) initn: 3395 init1: 3395 opt: 3395 Z-score: 2308.9 bits: 437.6 E(85289): 7.2e-122 Smith-Waterman score: 3395; 100.0% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KB1 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAAAAEPGARAWLGGGSPRPGSPACSPVLGSGGRARPGPGPGPGPERAGVRAPGPAAAPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKHVRIPCTSVAPSLVRVPV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHCFGPRGLHKRKFCAVCRKVLEAPALHCEVCELHLHPDCVPFACSDCRQCHQDGHQDHD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSLCSAALAPECGFGRLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLVLPPACVRLLPGGFSKTQSFRIVEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIFDGDDAVRRSQFRLVTVSRLAGAEEVLEAALRAHHIPEDPGHLELCRLPPSSQACDAW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGGKAGSAVISEEGRSPGSGEATPEAWVIRALPRAQEVLKIYPGWLKVGVAYVSVRVTPK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQMSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STARSVVLEVLPLLGRQAESPESFQLVEVAMGCRHVQRTMLMDEQPLLDRLQDIRQPPWC 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 QVSQTRFYVAESRDVAPHVSLFVGGLPPGLSPEEYSSLLHEAGATKATVVSVSHIYSSQG XP_016 P >>NP_003638 (OMIM: 601440,615008) diacylglycerol kinase (567 aa) initn: 1003 init1: 248 opt: 871 Z-score: 603.6 bits: 122.3 E(85289): 7e-27 Smith-Waterman score: 871; 40.4% identity (67.3% similar) in 361 aa overlap (576-928:207-559) 550 560 570 580 590 600 pF1KB1 VACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGLKGRDL ..: .:: . ::....: .:: :. : NP_003 CDFGEFKNLIIPPSYLTSINQMRKDKKTDYEVLASKLGKQWTPLIILANSRSGTNMGEGL 180 190 200 210 220 230 610 620 630 640 650 660 pF1KB1 LCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCF--RVLVCGGDGTVGWVLGALEETRYR : :: :::: ::::.:. :. .:.: . .: . ::::::::::::::: :... . . NP_003 LGEFRILLNPVQVFDVTKTPPIKALQLCTLLPYYSARVLVCGGDGTVGWVLDAVDDMKIK 240 250 260 270 280 290 670 680 690 700 710 720 pF1KB1 LACPE-PSVAILPLGTGNDLGRVLRWGAGYSGEDPFS-VLLSVDEADAVLMDRWTILLDA :.::.:::::::::. .: ::.::.:: : . :: .: :::.. .::: . . NP_003 GQEKYIPQVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQV-- 300 310 320 330 340 350 730 740 750 760 770 780 pF1KB1 HEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYVR ... . . :: :.:: ..: :: ..:.:: ::. :. :.::. ::.::. NP_003 -----TNKGYYNLRKPKEFTMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLF 360 370 380 390 400 790 800 810 820 830 pF1KB1 VGLQK--ISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRFEK : . ... ..:.:...:... ..: :::.::.: .:: ::.: :: . .: . NP_003 YGTKDCLVQECKDLNKKVELELDGERVALPSLEGIIVLNIGYWGGGCRLWEGMGDETYPL 410 420 430 440 450 460 840 850 860 870 880 890 pF1KB1 PRMDDGLLEVVGVTGVVYMGQVQGGLRSGIRIAQGSYFRVTLLKAT--PVQVDGEPWVQA : :::::::::: : . .:.: : . .::.:. :. .:: . :.:::::::.:. NP_003 ARHDDGLLEVVGVYGSFHCAQIQVKLANPFRIGQAHTVRL-ILKCSMMPMQVDGEPWAQG 470 480 490 500 510 520 900 910 920 930 940 pF1KB1 PGHMIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR : . :. . . ...: ..: : NP_003 PCTVTITHKTHAMMLYFSGEQTDDDISSTSDQEDIKATE 530 540 550 560 >>XP_011523696 (OMIM: 601440,615008) PREDICTED: diacylgl (585 aa) initn: 1003 init1: 248 opt: 871 Z-score: 603.4 bits: 122.3 E(85289): 7.2e-27 Smith-Waterman score: 871; 40.4% identity (67.3% similar) in 361 aa overlap (576-928:225-577) 550 560 570 580 590 600 pF1KB1 VACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGLKGRDL ..: .:: . ::....: .:: :. : XP_011 CDFGEFKNLIIPPSYLTSINQMRKDKKTDYEVLASKLGKQWTPLIILANSRSGTNMGEGL 200 210 220 230 240 250 610 620 630 640 650 660 pF1KB1 LCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCF--RVLVCGGDGTVGWVLGALEETRYR : :: :::: ::::.:. :. .:.: . .: . ::::::::::::::: :... . . XP_011 LGEFRILLNPVQVFDVTKTPPIKALQLCTLLPYYSARVLVCGGDGTVGWVLDAVDDMKIK 260 270 280 290 300 310 670 680 690 700 710 720 pF1KB1 LACPE-PSVAILPLGTGNDLGRVLRWGAGYSGEDPFS-VLLSVDEADAVLMDRWTILLDA :.::.:::::::::. .: ::.::.:: : . :: .: :::.. .::: . . XP_011 GQEKYIPQVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQV-- 320 330 340 350 360 370 730 740 750 760 770 780 pF1KB1 HEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYVR ... . . :: :.:: ..: :: ..:.:: ::. :. :.::. ::.::. XP_011 -----TNKGYYNLRKPKEFTMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLF 380 390 400 410 420 790 800 810 820 830 pF1KB1 VGLQK--ISHSRSLHKQIRLQVERQEVELPSIEGLIFINIPSWGSGADLWGSDSDTRFEK : . ... ..:.:...:... ..: :::.::.: .:: ::.: :: . .: . XP_011 YGTKDCLVQECKDLNKKVELELDGERVALPSLEGIIVLNIGYWGGGCRLWEGMGDETYPL 430 440 450 460 470 480 840 850 860 870 880 890 pF1KB1 PRMDDGLLEVVGVTGVVYMGQVQGGLRSGIRIAQGSYFRVTLLKAT--PVQVDGEPWVQA : :::::::::: : . .:.: : . .::.:. :. .:: . :.:::::::.:. XP_011 ARHDDGLLEVVGVYGSFHCAQIQVKLANPFRIGQAHTVRL-ILKCSMMPMQVDGEPWAQG 490 500 510 520 530 540 900 910 920 930 940 pF1KB1 PGHMIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR : . :. . . ...: ..: : XP_011 PCTVTITHKTHAMMLYFSGEQTDDDISSTSDQEDIKATE 550 560 570 580 >>XP_011518725 (OMIM: 601441) PREDICTED: diacylglycerol (809 aa) initn: 638 init1: 307 opt: 832 Z-score: 575.2 bits: 117.6 E(85289): 2.7e-25 Smith-Waterman score: 832; 40.8% identity (68.3% similar) in 375 aa overlap (575-938:163-523) 550 560 570 580 590 600 pF1KB1 DVACFAEAERLYMLLKDMAVRGRLLTALVLPDLLHAKLPPDSCPLLVFVNPKSGGLKGRD : ... : :::::::::::: .: XP_011 QNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAK 140 150 160 170 180 190 610 620 630 640 650 660 pF1KB1 LLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLVCGGDGTVGWVLGALEETRYRL .. :: :::.:::::..::: .:... .: .:.:.:::::::::.:..:.. : . XP_011 IIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLK- 200 210 220 230 240 250 670 680 690 700 710 720 pF1KB1 ACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLS-VDEADAVLMDRWTILLDAH- : : ::::::::::::.:.: ::.::. : : : .:: :.:...: .::: . . . XP_011 --PPPPVAILPLGTGNDLARTLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHAEPNP 260 270 280 290 300 730 740 750 760 770 780 pF1KB1 EAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQAREEEPGKFTSRLHNKGVYVRV ::: . : . .. . ..:: ..:.::...:.::..:: .: ::.::..:: :. . XP_011 EAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGT 310 320 330 340 350 360 790 800 810 820 830 pF1KB1 GLQK--ISHSRSLHKQIRLQVERQEVELPSIEGL-----IFINIPSWGSGADLWGSDSDT ... .. :..: :.::. . ... :.:. : .:.::: . .:. :: .. XP_011 AFSDFLMGSSKDLAKHIRVVCDGMDLT-PKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEH 370 380 390 400 410 420 840 850 860 870 880 890 pF1KB1 R-FEKPRMDDGLLEVVGVTGVVYMGQVQ-GGLRSGIRIAQGSYFRVTLLKATPVQVDGEP . :: : ::: :::.: : .. .. .: :: : :..: .: :: :::::::: XP_011 HDFEPQRHDDGYLEVIGFT-MTSLAALQVGG--HGERLTQCREVVLTTSKAIPVQVDGEP 430 440 450 460 470 480 900 910 920 930 940 pF1KB1 WVQAPGHMIISAAGPKVHMLRKAKQKPRRAGTTRDARADAAPAPESDPR : ... : : .. :..::: ::... ..: :.:: XP_011 CKLAASRIRI-ALRNQATMVQKAK---RRSAAP--LHSDQQPVPEQLRIQVSRVSMHDYE 490 500 510 520 530 XP_011 ALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCF 540 550 560 570 580 590 942 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:50:39 2016 done: Thu Nov 3 11:50:41 2016 Total Scan time: 15.290 Total Display time: 0.190 Function used was FASTA [36.3.4 Apr, 2011]