Result of FASTA (omim) for
pF1KB1389
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB1389, 648 aa
1>>>pF1KB1389 648 - 648 aa - 648 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6306+/-0.000324; mu= 11.4609+/- 0.020
mean_var=177.7429+/-36.047, 0's: 0 Z-trim(122.0): 32 B-trim: 655 in 1/55
Lambda= 0.096201
statistics sampled from 39443 (39475) to 39443 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.463), width: 16
Scan time: 10.110
The best scores are: opt bits E(85289)
NP_003496 (OMIM: 603408) frizzled-1 [Homo sapiens] ( 647) 4514 638.7 2e-182
NP_003498 (OMIM: 603410) frizzled-7 precursor [Hom ( 574) 3096 441.8 3.2e-123
NP_001457 (OMIM: 600667) frizzled-2 precursor [Hom ( 565) 3088 440.7 6.8e-123
NP_003459 (OMIM: 601723) frizzled-5 precursor [Hom ( 585) 1609 235.4 4.3e-61
XP_016869330 (OMIM: 606143) PREDICTED: frizzled-3 ( 599) 1306 193.4 2e-48
NP_665873 (OMIM: 606143) frizzled-3 precursor [Hom ( 666) 1306 193.4 2.2e-48
NP_059108 (OMIM: 606143) frizzled-3 precursor [Hom ( 666) 1306 193.4 2.2e-48
NP_001158088 (OMIM: 603409,614157) frizzled-6 isof ( 674) 1265 187.8 1.1e-46
NP_001158087 (OMIM: 603409,614157) frizzled-6 isof ( 706) 1265 187.8 1.2e-46
NP_003497 (OMIM: 603409,614157) frizzled-6 isoform ( 706) 1265 187.8 1.2e-46
NP_009128 (OMIM: 606147) frizzled-10 precursor [Ho ( 581) 1213 180.5 1.5e-44
XP_016869332 (OMIM: 606143) PREDICTED: frizzled-3 ( 491) 1196 178.1 6.8e-44
XP_016869331 (OMIM: 606143) PREDICTED: frizzled-3 ( 502) 1196 178.1 6.9e-44
XP_016869333 (OMIM: 606143) PREDICTED: frizzled-3 ( 470) 1195 177.9 7.2e-44
NP_003499 (OMIM: 601766) frizzled-9 precursor [Hom ( 591) 1147 171.3 8.7e-42
NP_036325 (OMIM: 133780,604579) frizzled-4 precurs ( 537) 1055 158.5 5.6e-38
NP_114072 (OMIM: 606146) frizzled-8 precursor [Hom ( 694) 833 127.8 1.3e-28
NP_001304725 (OMIM: 603409,614157) frizzled-6 isof ( 401) 700 109.1 3.1e-23
XP_011514824 (OMIM: 601500,601707,605462) PREDICTE ( 657) 604 96.0 4.5e-19
NP_005622 (OMIM: 601500,601707,605462) smoothened ( 787) 604 96.1 5.2e-19
NP_001454 (OMIM: 165720,605083) secreted frizzled- ( 325) 435 72.3 3.1e-12
NP_003005 (OMIM: 265900,606570) secreted frizzled- ( 346) 417 69.8 1.8e-11
NP_003004 (OMIM: 604157) secreted frizzled-related ( 295) 374 63.8 1e-09
NP_003006 (OMIM: 604158) secreted frizzled-related ( 317) 373 63.7 1.2e-09
NP_003003 (OMIM: 604156) secreted frizzled-related ( 314) 363 62.3 3.1e-09
NP_001265515 (OMIM: 605236,614595) atrial natriure ( 734) 337 59.0 7.1e-08
NP_001265514 (OMIM: 605236,614595) atrial natriure ( 938) 337 59.1 8.4e-08
NP_006578 (OMIM: 605236,614595) atrial natriuretic (1042) 337 59.1 9.1e-08
NP_113621 (OMIM: 606227,609549,611040) membrane fr ( 579) 281 51.1 1.3e-05
NP_003643 (OMIM: 603105) carboxypeptidase Z isofor ( 641) 237 45.1 0.00096
NP_001014447 (OMIM: 603105) carboxypeptidase Z iso ( 652) 229 44.0 0.0021
>>NP_003496 (OMIM: 603408) frizzled-1 [Homo sapiens] (647 aa)
initn: 3945 init1: 3945 opt: 4514 Z-score: 3396.2 bits: 638.7 E(85289): 2e-182
Smith-Waterman score: 4514; 99.8% identity (99.8% similar) in 648 aa overlap (1-648:1-647)
10 20 30 40 50 60
pF1KB1 MAEEEAPKKSRAAGGGASWELCAGALSARLAEEGSGDAGGRRRPPVDPRRLARQLLLLLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAEEEAPKKSRAAGGGASWELCAGALSARLAEEGSGDAGGRRRPPVDPRRLARQLLLLLW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 LLEAPLLLGVRAQAAGQGPGQGPGPGQQPPPPPPQQQQSGQQYNGERGISVPDHGYCQPI
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
NP_003 LLEAPLLLGVRAQAAGQGPGQGPGPGQQPPPPP-QQQQSGQQYNGERGISVPDHGYCQPI
70 80 90 100 110
130 140 150 160 170 180
pF1KB1 SIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB1 LEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB1 PSLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSCPRALKVPSYLNYHFLGEKDCGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PSLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSCPRALKVPSYLNYHFLGEKDCGAP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB1 CEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB1 GCYTAVAVAYIAGFLLEDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GCYTAVAVAYIAGFLLEDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIW
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB1 WVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFV
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB1 GLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGV
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB1 FSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPD
540 550 560 570 580 590
610 620 630 640
pF1KB1 FTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
600 610 620 630 640
>>NP_003498 (OMIM: 603410) frizzled-7 precursor [Homo sa (574 aa)
initn: 3093 init1: 1890 opt: 3096 Z-score: 2333.3 bits: 441.8 E(85289): 3.2e-123
Smith-Waterman score: 3096; 79.9% identity (90.6% similar) in 553 aa overlap (101-648:33-574)
80 90 100 110 120 130
pF1KB1 RAQAAGQGPGQGPGPGQQPPPPPPQQQQSGQQYNGERGISVPDHGYCQPISIPLCTDIAY
: :.::.::::::::.::::::::::::::
NP_003 DPGAAAPLSSLGLCALVLALLGALSAGAGAQPYHGEKGISVPDHGFCQPISIPLCTDIAY
10 20 30 40 50 60
140 150 160 170 180 190
pF1KB1 NQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRS
::::.:::::::::::::::::::::::::::: ::.::::::::::::::.::.:::::
NP_003 NQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRS
70 80 90 100 110 120
200 210 220 230 240 250
pF1KB1 LCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTS
:::::::::::::::::::::. :.::.::::::::.:::::::: :. :. : . .
NP_003 LCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSD-GSGGPGGGPTAYPT
130 140 150 160 170 180
260 270 280 290 300
pF1KB1 NPQHGGGGHRGGFPGGAGASERGK----FSCPRALKVPSYLNYHFLGEKDCGAPCEPTKV
: . .: :: .. ::. ::::: :::: ::.:.::::.:::::::: ..
NP_003 APYLPDLPFTA-LPPGA-SDGRGRPAFPFSCPRQLKVPPYLGYRFLGERDCGAPCEPGRA
190 200 210 220 230
310 320 330 340 350 360
pF1KB1 YGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAV
::::: :: ::.: :.:.::::::::::::::::::::::::::::::::::::: :
NP_003 NGLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMV
240 250 260 270 280 290
370 380 390 400 410 420
pF1KB1 AVAYIAGFLLEDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSL
:::..::::::::.:: ..:..:: :::::::::::::::::.::::.::::::::::::
NP_003 AVAHVAGFLLEDRAVCVERFSDDGYRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSL
300 310 320 330 340 350
430 440 450 460 470 480
pF1KB1 TWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVD
:::::::::::::::::::::::::::::::.:::::::.::::::.:::::.:::..::
NP_003 TWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVD
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB1 ALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYT
420 430 440 450 460 470
550 560 570 580 590 600
pF1KB1 VPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPH-PPMSPDFTVFM
::::::.::::::::::..:::.:. :.:::::.::: : : :::::::::::
NP_003 VPATIVLACYFYEQAFREHWERTWLLQTCKSYAVPCP--------PGHFPPMSPDFTVFM
480 490 500 510 520 530
610 620 630 640
pF1KB1 IKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
::::::.:::::.::::::::::.:::.:: ::..:..:::.:
NP_003 IKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRLSHSSKGETAV
540 550 560 570
>>NP_001457 (OMIM: 600667) frizzled-2 precursor [Homo sa (565 aa)
initn: 3069 init1: 1869 opt: 3088 Z-score: 2327.4 bits: 440.7 E(85289): 6.8e-123
Smith-Waterman score: 3088; 80.4% identity (90.0% similar) in 552 aa overlap (102-648:24-565)
80 90 100 110 120 130
pF1KB1 AQAAGQGPGQGPGPGQQPPPPPPQQQQSGQQYNGERGISVPDHGYCQPISIPLCTDIAYN
:..::.:::.::::.:::::::::::::::
NP_001 MRPRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYN
10 20 30 40 50
140 150 160 170 180 190
pF1KB1 QTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSL
:::::::::::::::::::::::::::::::: ::.:::::::::::::::::.:::::.
NP_001 QTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSI
60 70 80 90 100 110
200 210 220 230 240 250
pF1KB1 CERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSN
::::::::::::::::::::. :.::.:: ::: ..::::: :. :.: .:: .
NP_001 CERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAP--ALLTTAPPPG
120 130 140 150 160 170
260 270 280 290 300
pF1KB1 PQHGGGGHRGGFPGGAGASER-----GKFSCPRALKVPSYLNYHFLGEKDCGAPCEPTKV
: :.:: :: :::.:: : : :::.:::::::.:.::::.::.:::::..
NP_001 LQPGAGGTPGG-PGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARP
180 190 200 210 220 230
310 320 330 340 350 360
pF1KB1 YGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAV
: :.:. :: ::.: :: :::::::::.::: ::::::.:: :::::::::::::: :
NP_001 DGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMV
240 250 260 270 280 290
370 380 390 400 410 420
pF1KB1 AVAYIAGFLLEDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSL
.:::::::.:..:::::..:.::: :::.:::::::::::::::::::::::::::::::
NP_001 SVAYIAGFVLQERVVCNERFSEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSL
300 310 320 330 340 350
430 440 450 460 470 480
pF1KB1 TWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVD
:::::::::::::::::::::::::::::::.:::::::.::.:::.::::::::::..:
NP_001 TWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLD
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB1 ALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYT
:::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_001 PLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYT
420 430 440 450 460 470
550 560 570 580 590 600
pF1KB1 VPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDFTVFMI
:::::::::::::::::..::::::.: ::: ::::: : : :::::::.::
NP_001 VPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCP-------AHYTPRMSPDFTVYMI
480 490 500 510 520
610 620 630 640
pF1KB1 KYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
::::::::::::::::::::::.::::::::::::..:::::
NP_001 KYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTNSRHGETTV
530 540 550 560
>>NP_003459 (OMIM: 601723) frizzled-5 precursor [Homo sa (585 aa)
initn: 1724 init1: 846 opt: 1609 Z-score: 1217.8 bits: 235.4 E(85289): 4.3e-61
Smith-Waterman score: 1814; 48.8% identity (71.4% similar) in 562 aa overlap (89-637:6-536)
60 70 80 90 100 110
pF1KB1 LWLLEAPLLLGVRAQAAGQGPGQGPGPGQQPPPPPPQQQQSGQQYNGERGISVPDHGYCQ
: :: : : :. .. ::
NP_003 MARPDPSAPPSLLLLLLAQLVG-RAAAASKAPVCQ
10 20 30
120 130 140 150 160 170
pF1KB1 PISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVC
:..:.: :.:: : ::: ..: .:..::::::::.:::..::: .:.:::::::.:.:
NP_003 EITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPIC
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB1 TV-LEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHG--AGELCVGQNTSD
.. ::::::.::::. :: :: ..:: ::. ..:...:: : : ::. : :.
NP_003 LPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGRDAEVLCMDYNRSE
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB1 KGTPTPSLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSCP-RALKVPSYLNYHFLGE
: : .: : :. . : :.: : : : : :: . : : .
NP_003 ATTAPPRPFPAKPTLPGPPGAPASGGECPAG------GPFVCKCREPFVPILKESHPLYN
160 170 180 190 200
300 310 320 330 340
pF1KB1 K-------DCGAPC-EPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDM
: .:..:: .:. :. .: :. :::.::::: :: :: :.:.::
NP_003 KVRTGQVPNCAVPCYQPS-------FSADERTFATFWIGLWSVLCFISTSTTVATFLIDM
210 220 230 240 250 260
350 360 370 380 390 400
pF1KB1 RRFSYPERPIIFLSGCYTAVAVAYIAGFLL-EDRVVCNDKFAEDGARTVAQGTKKEGCTI
.:: ::::::::::.:: :...... ... . :.:. . . .:.. . :::
NP_003 ERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHNHIHYETTGPAL----CTI
270 280 290 300 310
410 420 430 440 450 460
pF1KB1 LFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILA
.:...:::.:::::::::::::::::::::::.::: . .:::::::: .:..:.:: ::
NP_003 VFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALA
320 330 340 350 360 370
470 480 490 500 510 520
pF1KB1 LGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDG
:..:::: ..:.:.:: .:...::::::.:: .::..:: :::::::::::::...:. :
NP_003 LSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGG
380 390 400 410 420 430
530 540 550 560 570 580
pF1KB1 TKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHL
:::.::::::.:::.:..::::::.::.:::.::: .:..:: .: .: ::
NP_003 TKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQHYRESWE---AALTCA-----CPGH
440 450 460 470 480
590 600 610 620 630 640
pF1KB1 QAGGGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGE
..: .: .:.. :.:.::.: :.:::::: :::::::..:::.: .:
NP_003 DTG-----QPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVESWRRFTSRCCCRPRRG
490 500 510 520 530 540
pF1KB1 TTV
NP_003 HKSGGAMAAGDYPEASAALTGRTGPPGPAATYHKQVSLSHV
550 560 570 580
>>XP_016869330 (OMIM: 606143) PREDICTED: frizzled-3 isof (599 aa)
initn: 1244 init1: 813 opt: 1306 Z-score: 990.4 bits: 193.4 E(85289): 2e-48
Smith-Waterman score: 1506; 47.2% identity (69.9% similar) in 481 aa overlap (157-635:1-444)
130 140 150 160 170 180
pF1KB1 DIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALP
.:...:: ... :::..:::.: ..
XP_016 MVNLDCSRDFRPFLCALYAPICMEYGRVTL
10 20 30
190 200 210 220 230 240
pF1KB1 PCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPE
::: ::.:: . : ::. :: ::. ..: .:: : : : :.
XP_016 PCRRLCQRAYSECSKLMEMFGVPWPEDMECSRFP--------------DCDEPYPRLVDL
40 50 60 70
250 260 270 280 290 300
pF1KB1 FWTSNPQHGGGGHRGGFPGGAGASERGKFSCPRALKVPSYLNYHFLGEKDCGAPCEPTKV
...: .:. : : . : : ::: ::. :.: :: .::. :: :.
XP_016 NLAGEPTEGA-------PV-AVQRDYG-FWCPRELKIDPDLGYSFLHVRDCSPPC-PN--
80 90 100 110 120
310 320 330 340 350 360
pF1KB1 YGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAV
::: ::: :.: .::. :..: ..:::: ::.:.:. :: :::::::: . :: :
XP_016 ---MYFRREELSFARYFIGLISIICLSATLFTFLTFLIDVTRFRYPERPIIFYAVCYMMV
130 140 150 160 170 180
370 380 390 400 410 420
pF1KB1 AVAYIAGFLLEDRVVCNDKF-AEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWWVILS
.. .. ::::::::.:: .. :. : ::.::.....::.:::.::::.::.:.:::::.
XP_016 SLIFFIGFLLEDRVACNASIPAQYKASTVTQGSHNKACTMLFMILYFFTMAGSVWWVILT
190 200 210 220 230 240
430 440 450 460 470 480
pF1KB1 LTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNV
.:::::: ::: :::: .. :: .::..:. :: .::.....:: .:::::::: .:
XP_016 ITWFLAAVPKWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDV
250 260 270 280 290 300
490 500 510 520 530 540
pF1KB1 DALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLY
:::: :::::: .:. .:.:.::::..:: :.: . . . .:: :.:.::::::.::
XP_016 DALRYFVLAPLCLYVVVGVSLLLAGIISLNRVRIEIPLEKENQDKLVKFMIRIGVFSILY
310 320 330 340 350 360
550 560 570 580 590 600
pF1KB1 TVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMS-PDFTVF
:: .::.:::::::.: :: .:. . :. : ::::. :. :: ::. .:
XP_016 LVPLLVVIGCYFYEQAYRGIWETTWIQERCREYHIPCPY-QV-------TQMSRPDLILF
370 380 390 400 410
610 620 630 640
pF1KB1 MIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
..::::.::::: : ::. : :: : .:.
XP_016 LMKYLMALIVGIPSVFWVGSKKTCFEWASFFHGRRKKEIVNESRQVLQEPDFAQSLLRDP
420 430 440 450 460 470
XP_016 NTPIIRKSRGTSTQGTSTHASSTQLAMVDDQRSKAGSIHSKVSSYHGSLHRSRDGRYTPC
480 490 500 510 520 530
>>NP_665873 (OMIM: 606143) frizzled-3 precursor [Homo sa (666 aa)
initn: 1399 init1: 813 opt: 1306 Z-score: 989.8 bits: 193.4 E(85289): 2.2e-48
Smith-Waterman score: 1661; 47.2% identity (70.6% similar) in 521 aa overlap (117-635:28-511)
90 100 110 120 130 140
pF1KB1 QQPPPPPPQQQQSGQQYNGERGISVPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQED
:.::.. .: :. :: :.:::::.: .:.
NP_665 MAMTWIVFSLWPLTVFMGHIGGHSLFSCEPITLRMCQDLPYNTTFMPNLLNHYDQQT
10 20 30 40 50
150 160 170 180 190 200
pF1KB1 AGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKF
:.: .. :.:.:...:: ... :::..:::.: .. ::: ::.:: . : ::. :
NP_665 AALAMEPFHPMVNLDCSRDFRPFLCALYAPICMEYGRVTLPCRRLCQRAYSECSKLMEMF
60 70 80 90 100 110
210 220 230 240 250 260
pF1KB1 GFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGHRGGFPGG
: ::. ..: .:: : : : :. ...: .:. :
NP_665 GVPWPEDMECSRFP--------------DCDEPYPRLVDLNLAGEPTEGA-------PV-
120 130 140 150
270 280 290 300 310 320
pF1KB1 AGASERGKFSCPRALKVPSYLNYHFLGEKDCGAPCEPTKVYGLMYFGPEELRFSRTWIGI
: . : : ::: ::. :.: :: .::. :: :. ::: ::: :.: .::.
NP_665 AVQRDYG-FWCPRELKIDPDLGYSFLHVRDCSPPC-PN-----MYFRREELSFARYFIGL
160 170 180 190 200
330 340 350 360 370 380
pF1KB1 WSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKF
:..: ..:::: ::.:.:. :: :::::::: . :: :.. .. ::::::::.:: ..
NP_665 ISIICLSATLFTFLTFLIDVTRFRYPERPIIFYAVCYMMVSLIFFIGFLLEDRVACNASI
210 220 230 240 250 260
390 400 410 420 430 440
pF1KB1 -AEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANS
:. : ::.::.....::.:::.::::.::.:.:::::..:::::: ::: :::: ..
NP_665 PAQYKASTVTQGSHNKACTMLFMILYFFTMAGSVWWVILTITWFLAAVPKWGSEAIEKKA
270 280 290 300 310 320
450 460 470 480 490 500
pF1KB1 QYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTS
:: .::..:. :: .::.....:: .:::::::: .::::: :::::: .:. .:.:
NP_665 LLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVDALRYFVLAPLCLYVVVGVS
330 340 350 360 370 380
510 520 530 540 550 560
pF1KB1 FLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQ
.::::..:: :.: . . . .:: :.:.::::::.:: :: .::.:::::::.:
NP_665 LLLAGIISLNRVRIEIPLEKENQDKLVKFMIRIGVFSILYLVPLLVVIGCYFYEQAYRGI
390 400 410 420 430 440
570 580 590 600 610 620
pF1KB1 WERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMS-PDFTVFMIKYLMTLIVGITSGFWIWS
:: .:. . :. : ::::. :. :: ::. .:..::::.::::: : ::. :
NP_665 WETTWIQERCREYHIPCPY-QV-------TQMSRPDLILFLMKYLMALIVGIPSVFWVGS
450 460 470 480 490 500
630 640
pF1KB1 GKTLNSWRKFYTRLTNSKQGETTV
:: : .:.
NP_665 KKTCFEWASFFHGRRKKEIVNESRQVLQEPDFAQSLLRDPNTPIIRKSRGTSTQGTSTHA
510 520 530 540 550 560
>>NP_059108 (OMIM: 606143) frizzled-3 precursor [Homo sa (666 aa)
initn: 1399 init1: 813 opt: 1306 Z-score: 989.8 bits: 193.4 E(85289): 2.2e-48
Smith-Waterman score: 1661; 47.2% identity (70.6% similar) in 521 aa overlap (117-635:28-511)
90 100 110 120 130 140
pF1KB1 QQPPPPPPQQQQSGQQYNGERGISVPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQED
:.::.. .: :. :: :.:::::.: .:.
NP_059 MAMTWIVFSLWPLTVFMGHIGGHSLFSCEPITLRMCQDLPYNTTFMPNLLNHYDQQT
10 20 30 40 50
150 160 170 180 190 200
pF1KB1 AGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKF
:.: .. :.:.:...:: ... :::..:::.: .. ::: ::.:: . : ::. :
NP_059 AALAMEPFHPMVNLDCSRDFRPFLCALYAPICMEYGRVTLPCRRLCQRAYSECSKLMEMF
60 70 80 90 100 110
210 220 230 240 250 260
pF1KB1 GFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGHRGGFPGG
: ::. ..: .:: : : : :. ...: .:. :
NP_059 GVPWPEDMECSRFP--------------DCDEPYPRLVDLNLAGEPTEGA-------PV-
120 130 140 150
270 280 290 300 310 320
pF1KB1 AGASERGKFSCPRALKVPSYLNYHFLGEKDCGAPCEPTKVYGLMYFGPEELRFSRTWIGI
: . : : ::: ::. :.: :: .::. :: :. ::: ::: :.: .::.
NP_059 AVQRDYG-FWCPRELKIDPDLGYSFLHVRDCSPPC-PN-----MYFRREELSFARYFIGL
160 170 180 190 200
330 340 350 360 370 380
pF1KB1 WSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKF
:..: ..:::: ::.:.:. :: :::::::: . :: :.. .. ::::::::.:: ..
NP_059 ISIICLSATLFTFLTFLIDVTRFRYPERPIIFYAVCYMMVSLIFFIGFLLEDRVACNASI
210 220 230 240 250 260
390 400 410 420 430 440
pF1KB1 -AEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANS
:. : ::.::.....::.:::.::::.::.:.:::::..:::::: ::: :::: ..
NP_059 PAQYKASTVTQGSHNKACTMLFMILYFFTMAGSVWWVILTITWFLAAVPKWGSEAIEKKA
270 280 290 300 310 320
450 460 470 480 490 500
pF1KB1 QYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTS
:: .::..:. :: .::.....:: .:::::::: .::::: :::::: .:. .:.:
NP_059 LLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVDALRYFVLAPLCLYVVVGVS
330 340 350 360 370 380
510 520 530 540 550 560
pF1KB1 FLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQ
.::::..:: :.: . . . .:: :.:.::::::.:: :: .::.:::::::.:
NP_059 LLLAGIISLNRVRIEIPLEKENQDKLVKFMIRIGVFSILYLVPLLVVIGCYFYEQAYRGI
390 400 410 420 430 440
570 580 590 600 610 620
pF1KB1 WERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMS-PDFTVFMIKYLMTLIVGITSGFWIWS
:: .:. . :. : ::::. :. :: ::. .:..::::.::::: : ::. :
NP_059 WETTWIQERCREYHIPCPY-QV-------TQMSRPDLILFLMKYLMALIVGIPSVFWVGS
450 460 470 480 490 500
630 640
pF1KB1 GKTLNSWRKFYTRLTNSKQGETTV
:: : .:.
NP_059 KKTCFEWASFFHGRRKKEIVNESRQVLQEPDFAQSLLRDPNTPIIRKSRGTSTQGTSTHA
510 520 530 540 550 560
>>NP_001158088 (OMIM: 603409,614157) frizzled-6 isoform (674 aa)
initn: 1302 init1: 781 opt: 1265 Z-score: 959.0 bits: 187.8 E(85289): 1.1e-46
Smith-Waterman score: 1538; 44.5% identity (73.0% similar) in 512 aa overlap (128-637:3-477)
100 110 120 130 140 150
pF1KB1 QSGQQYNGERGISVPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPL
.:::.:..:::.:: .: :..:...: ::
NP_001 MKMAYNMTFFPNLMGHYDQSIAAVEMEHFLPL
10 20 30
160 170 180 190 200 210
pF1KB1 VKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCE
....:: ... :::. ..:.: ...::::.:::.. . :. :.. ::..::. :.:.
NP_001 ANLECSPNIETFLCKAFVPTCIEQIHVVPPCRKLCEKVYSDCKKLIDTFGIRWPEELECD
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB1 KFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSC
.. . : :. .:. .. :. .::. ... : :
NP_001 RL------QYC------DETVPV-TFDPHTEFLGPQKKT----------EQVQRDIGFWC
100 110 120
280 290 300 310 320 330
pF1KB1 PRALKVPSYLNYHFLGEKDCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLF
:: ::. . .:.::: .:. :: :. ::: .::.:....:: :..: .:::
NP_001 PRHLKTSGGQGYKFLGIDQCAPPC-PN-----MYFKSDELEFAKSFIGTVSIFCLCATLF
130 140 150 160 170 180
340 350 360 370 380 390
pF1KB1 TVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCN--DKFAEDGARTVA
: ::.:.:.::: :::::::. : ::. :.. :. :::: : ..:: :. : : ::.
NP_001 TFLTFLIDVRRFRYPERPIIYYSVCYSIVSLMYFIGFLLGDSTACNKADEKLELGD-TVV
190 200 210 220 230 240
400 410 420 430 440 450
pF1KB1 QGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAV
:.....::.:::.::::.::...:::::..::::::: ::. :::: .. .:: .::..
NP_001 LGSQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGT
250 260 270 280 290 300
460 470 480 490 500 510
pF1KB1 PAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLF
:.. :. .::...:.:: .:::::::: ..:: : ::: :: . .:.: :.::::..::
NP_001 PGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGLSLLLAGIISLN
310 320 330 340 350 360
520 530 540 550 560 570
pF1KB1 RIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSC
..: ...::: . :::.:.:.:::::: :: :: . ...:: :::. : :: .::.. :
NP_001 HVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRITWEITWVSDHC
370 380 390 400 410 420
580 590 600 610 620 630
pF1KB1 KSYAIPCPHLQAGGGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFY
..: ::::. :: . : :....:::::::::::::.. ::. : :: . : :.
NP_001 RQYHIPCPY-QAKAKA------RPELALFMIKYLMTLIVGISAVFWVGSKKTCTEWAGFF
430 440 450 460 470
640
pF1KB1 TRLTNSKQGETTV
:
NP_001 KRNRKRDPISESRRVLQESCEFFLKHNSKVKHKKKHYKPSSHKLKVISKSMGTSTGATAN
480 490 500 510 520 530
>>NP_001158087 (OMIM: 603409,614157) frizzled-6 isoform (706 aa)
initn: 1343 init1: 781 opt: 1265 Z-score: 958.7 bits: 187.8 E(85289): 1.2e-46
Smith-Waterman score: 1592; 44.7% identity (72.8% similar) in 523 aa overlap (117-637:24-509)
90 100 110 120 130 140
pF1KB1 QQPPPPPPQQQQSGQQYNGERGISVPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQED
:.::..: : .:::.:..:::.:: .:
NP_001 MEMFTFLLTCIFLPLLRGHSLFTCEPITVPRCMKMAYNMTFFPNLMGHYDQSI
10 20 30 40 50
150 160 170 180 190 200
pF1KB1 AGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKF
:..:...: ::....:: ... :::. ..:.: ...::::.:::.. . :. :.. :
NP_001 AAVEMEHFLPLANLECSPNIETFLCKAFVPTCIEQIHVVPPCRKLCEKVYSDCKKLIDTF
60 70 80 90 100 110
210 220 230 240 250 260
pF1KB1 GFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGHRGGFPGG
:..::. :.:... . : :. .:. .. :. .::. .
NP_001 GIRWPEELECDRL------QYC------DETVPV-TFDPHTEFLGPQK----KTEQVQRD
120 130 140 150
270 280 290 300 310 320
pF1KB1 AGASERGKFSCPRALKVPSYLNYHFLGEKDCGAPCEPTKVYGLMYFGPEELRFSRTWIGI
: : ::: ::. . .:.::: .:. :: :. ::: .::.:....::
NP_001 IG------FWCPRHLKTSGGQGYKFLGIDQCAPPC-PN-----MYFKSDELEFAKSFIGT
160 170 180 190 200
330 340 350 360 370 380
pF1KB1 WSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCN--D
:..: .:::: ::.:.:.::: :::::::. : ::. :.. :. :::: : ..:: :
NP_001 VSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYSIVSLMYFIGFLLGDSTACNKAD
210 220 230 240 250 260
390 400 410 420 430 440
pF1KB1 KFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEAN
. : : ::. :.....::.:::.::::.::...:::::..::::::: ::. :::: .
NP_001 EKLELGD-TVVLGSQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQK
270 280 290 300 310 320
450 460 470 480 490 500
pF1KB1 SQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGT
. .:: .::..:.. :. .::...:.:: .:::::::: ..:: : ::: :: . .:.:
NP_001 AVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGL
330 340 350 360 370 380
510 520 530 540 550 560
pF1KB1 SFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRD
:.::::..:: ..: ...::: . :::.:.:.:::::: :: :: . ...:: :::. :
NP_001 SLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRI
390 400 410 420 430 440
570 580 590 600 610 620
pF1KB1 QWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWS
:: .::.. :..: ::::. :: . : :....:::::::::::::.. ::. :
NP_001 TWEITWVSDHCRQYHIPCPY-QAKAKA------RPELALFMIKYLMTLIVGISAVFWVGS
450 460 470 480 490
630 640
pF1KB1 GKTLNSWRKFYTRLTNSKQGETTV
:: . : :. :
NP_001 KKTCTEWAGFFKRNRKRDPISESRRVLQESCEFFLKHNSKVKHKKKHYKPSSHKLKVISK
500 510 520 530 540 550
>>NP_003497 (OMIM: 603409,614157) frizzled-6 isoform a p (706 aa)
initn: 1343 init1: 781 opt: 1265 Z-score: 958.7 bits: 187.8 E(85289): 1.2e-46
Smith-Waterman score: 1592; 44.7% identity (72.8% similar) in 523 aa overlap (117-637:24-509)
90 100 110 120 130 140
pF1KB1 QQPPPPPPQQQQSGQQYNGERGISVPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQED
:.::..: : .:::.:..:::.:: .:
NP_003 MEMFTFLLTCIFLPLLRGHSLFTCEPITVPRCMKMAYNMTFFPNLMGHYDQSI
10 20 30 40 50
150 160 170 180 190 200
pF1KB1 AGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKF
:..:...: ::....:: ... :::. ..:.: ...::::.:::.. . :. :.. :
NP_003 AAVEMEHFLPLANLECSPNIETFLCKAFVPTCIEQIHVVPPCRKLCEKVYSDCKKLIDTF
60 70 80 90 100 110
210 220 230 240 250 260
pF1KB1 GFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGHRGGFPGG
:..::. :.:... . : :. .:. .. :. .::. .
NP_003 GIRWPEELECDRL------QYC------DETVPV-TFDPHTEFLGPQK----KTEQVQRD
120 130 140 150
270 280 290 300 310 320
pF1KB1 AGASERGKFSCPRALKVPSYLNYHFLGEKDCGAPCEPTKVYGLMYFGPEELRFSRTWIGI
: : ::: ::. . .:.::: .:. :: :. ::: .::.:....::
NP_003 IG------FWCPRHLKTSGGQGYKFLGIDQCAPPC-PN-----MYFKSDELEFAKSFIGT
160 170 180 190 200
330 340 350 360 370 380
pF1KB1 WSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCN--D
:..: .:::: ::.:.:.::: :::::::. : ::. :.. :. :::: : ..:: :
NP_003 VSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYSIVSLMYFIGFLLGDSTACNKAD
210 220 230 240 250 260
390 400 410 420 430 440
pF1KB1 KFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEAN
. : : ::. :.....::.:::.::::.::...:::::..::::::: ::. :::: .
NP_003 EKLELGD-TVVLGSQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQK
270 280 290 300 310 320
450 460 470 480 490 500
pF1KB1 SQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGT
. .:: .::..:.. :. .::...:.:: .:::::::: ..:: : ::: :: . .:.:
NP_003 AVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGL
330 340 350 360 370 380
510 520 530 540 550 560
pF1KB1 SFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRD
:.::::..:: ..: ...::: . :::.:.:.:::::: :: :: . ...:: :::. :
NP_003 SLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRI
390 400 410 420 430 440
570 580 590 600 610 620
pF1KB1 QWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWS
:: .::.. :..: ::::. :: . : :....:::::::::::::.. ::. :
NP_003 TWEITWVSDHCRQYHIPCPY-QAKAKA------RPELALFMIKYLMTLIVGISAVFWVGS
450 460 470 480 490
630 640
pF1KB1 GKTLNSWRKFYTRLTNSKQGETTV
:: . : :. :
NP_003 KKTCTEWAGFFKRNRKRDPISESRRVLQESCEFFLKHNSKVKHKKKHYKPSSHKLKVISK
500 510 520 530 540 550
648 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 20:25:48 2016 done: Thu Nov 3 20:25:49 2016
Total Scan time: 10.110 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]