FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB1393, 810 aa 1>>>pF1KB1393 810 - 810 aa - 810 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.1238+/-0.000472; mu= -12.4223+/- 0.029 mean_var=372.7852+/-78.132, 0's: 0 Z-trim(119.2): 138 B-trim: 445 in 1/52 Lambda= 0.066427 statistics sampled from 32795 (32935) to 32795 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.386), width: 16 Scan time: 13.280 The best scores are: opt bits E(85289) XP_016873933 (OMIM: 603142) PREDICTED: liprin-beta ( 810) 5365 529.1 3e-149 XP_006718414 (OMIM: 603142) PREDICTED: liprin-beta ( 850) 5336 526.3 2.1e-148 XP_006718413 (OMIM: 603142) PREDICTED: liprin-beta ( 887) 5249 518.0 7.2e-146 XP_011518718 (OMIM: 603142) PREDICTED: liprin-beta ( 897) 5220 515.2 5e-145 XP_011518716 (OMIM: 603142) PREDICTED: liprin-beta ( 927) 5220 515.2 5.1e-145 XP_006718412 (OMIM: 603142) PREDICTED: liprin-beta ( 927) 5220 515.2 5.1e-145 XP_011518715 (OMIM: 603142) PREDICTED: liprin-beta ( 927) 5220 515.2 5.1e-145 XP_011518717 (OMIM: 603142) PREDICTED: liprin-beta ( 900) 5219 515.1 5.3e-145 XP_011518719 (OMIM: 603142) PREDICTED: liprin-beta ( 858) 5217 514.9 5.8e-145 XP_011518720 (OMIM: 603142) PREDICTED: liprin-beta ( 815) 5026 496.6 1.8e-139 XP_011518721 (OMIM: 603142) PREDICTED: liprin-beta ( 769) 4811 476.0 2.8e-133 XP_011518722 (OMIM: 603142) PREDICTED: liprin-beta ( 769) 4811 476.0 2.8e-133 XP_006718416 (OMIM: 603142) PREDICTED: liprin-beta ( 784) 4787 473.7 1.4e-132 XP_016873936 (OMIM: 603142) PREDICTED: liprin-beta ( 750) 4700 465.3 4.3e-130 NP_003612 (OMIM: 603142) liprin-beta-2 isoform 1 [ ( 876) 2864 289.4 4.5e-77 NP_001243497 (OMIM: 603142) liprin-beta-2 isoform ( 764) 2861 289.1 4.9e-77 NP_001243498 (OMIM: 603142) liprin-beta-2 isoform ( 733) 2855 288.5 7.1e-77 XP_016873932 (OMIM: 603142) PREDICTED: liprin-beta ( 876) 2853 288.4 9.4e-77 XP_016873935 (OMIM: 603142) PREDICTED: liprin-beta ( 799) 2850 288.1 1.1e-76 XP_016873934 (OMIM: 603142) PREDICTED: liprin-beta ( 807) 2850 288.1 1.1e-76 XP_005253234 (OMIM: 603142) PREDICTED: liprin-beta ( 916) 2824 285.6 6.7e-76 XP_006718415 (OMIM: 603142) PREDICTED: liprin-beta ( 839) 2821 285.3 7.6e-76 XP_016875547 (OMIM: 603141) PREDICTED: liprin-beta (1023) 1668 174.9 1.6e-42 XP_005253565 (OMIM: 603141) PREDICTED: liprin-beta (1026) 1653 173.4 4.4e-42 NP_001185845 (OMIM: 603141) liprin-beta-1 isoform ( 980) 1652 173.3 4.6e-42 XP_016875555 (OMIM: 603141) PREDICTED: liprin-beta ( 995) 1650 173.1 5.3e-42 XP_016875560 (OMIM: 603141) PREDICTED: liprin-beta ( 984) 1649 173.0 5.6e-42 XP_016875562 (OMIM: 603141) PREDICTED: liprin-beta ( 981) 1646 172.7 6.8e-42 XP_016875550 (OMIM: 603141) PREDICTED: liprin-beta (1022) 1643 172.5 8.6e-42 XP_016875559 (OMIM: 603141) PREDICTED: liprin-beta ( 991) 1641 172.3 9.6e-42 XP_016875561 (OMIM: 603141) PREDICTED: liprin-beta ( 983) 1640 172.2 1e-41 NP_001185844 (OMIM: 603141) liprin-beta-1 isoform ( 858) 1638 171.9 1e-41 NP_803193 (OMIM: 603141) liprin-beta-1 isoform 2 [ (1011) 1638 172.0 1.2e-41 XP_005253564 (OMIM: 603141) PREDICTED: liprin-beta (1033) 1637 171.9 1.3e-41 XP_006719222 (OMIM: 603141) PREDICTED: liprin-beta ( 883) 1633 171.5 1.5e-41 XP_016875545 (OMIM: 603141) PREDICTED: liprin-beta (1036) 1633 171.5 1.7e-41 XP_016875546 (OMIM: 603141) PREDICTED: liprin-beta (1036) 1633 171.5 1.7e-41 XP_005253562 (OMIM: 603141) PREDICTED: liprin-beta (1036) 1633 171.5 1.7e-41 XP_016875553 (OMIM: 603141) PREDICTED: liprin-beta (1002) 1631 171.3 1.9e-41 XP_016875549 (OMIM: 603141) PREDICTED: liprin-beta (1015) 1631 171.3 1.9e-41 XP_016875558 (OMIM: 603141) PREDICTED: liprin-beta ( 991) 1630 171.2 2e-41 XP_016875548 (OMIM: 603141) PREDICTED: liprin-beta (1025) 1628 171.0 2.3e-41 XP_016875564 (OMIM: 603141) PREDICTED: liprin-beta ( 841) 1625 170.7 2.4e-41 NP_003613 (OMIM: 603141) liprin-beta-1 isoform 1 [ (1005) 1627 170.9 2.5e-41 XP_016875563 (OMIM: 603141) PREDICTED: liprin-beta ( 861) 1625 170.7 2.5e-41 XP_005253566 (OMIM: 603141) PREDICTED: liprin-beta (1025) 1626 170.8 2.7e-41 XP_016875557 (OMIM: 603141) PREDICTED: liprin-beta ( 994) 1625 170.7 2.8e-41 XP_016875551 (OMIM: 603141) PREDICTED: liprin-beta (1014) 1625 170.7 2.8e-41 XP_016875556 (OMIM: 603141) PREDICTED: liprin-beta ( 994) 1623 170.5 3.2e-41 XP_016875565 (OMIM: 603141) PREDICTED: liprin-beta ( 687) 1614 169.6 4.3e-41 >>XP_016873933 (OMIM: 603142) PREDICTED: liprin-beta-2 i (810 aa) initn: 5365 init1: 5365 opt: 5365 Z-score: 2800.5 bits: 529.1 E(85289): 3e-149 Smith-Waterman score: 5365; 99.9% identity (99.9% similar) in 810 aa overlap (1-810:1-810) 10 20 30 40 50 60 pF1KB1 MDGDIDVYKHFSWLKRSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDGDIDVYKHFSWLKRSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 KIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 QEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 HSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 MVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKSLE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 TRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFLAEHKYPTLPGKLSGATPNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFLAEHKYPTLPGKLSGATPNGE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 AAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWDDTAVVNDLSSTSSGTESGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWDDTAVVNDLSSTSSGTESGPQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 SPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSRTRDSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSRTRDSKG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 QKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKELGIKHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKELGIKHP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 LHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTV ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_016 LHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDRRMLQYLTV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 NDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEW 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 LRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 PEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPMEPSDGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPMEPSDGVS 730 740 750 760 770 780 790 800 810 pF1KB1 DSHRVYSGYRGLSPLDAPELDGLDQVGQIS :::::::::::::::::::::::::::::: XP_016 DSHRVYSGYRGLSPLDAPELDGLDQVGQIS 790 800 810 >>XP_006718414 (OMIM: 603142) PREDICTED: liprin-beta-2 i (850 aa) initn: 5396 init1: 5336 opt: 5336 Z-score: 2785.2 bits: 526.3 E(85289): 2.1e-148 Smith-Waterman score: 5336; 99.8% identity (99.9% similar) in 806 aa overlap (1-806:1-806) 10 20 30 40 50 60 pF1KB1 MDGDIDVYKHFSWLKRSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MDGDIDVYKHFSWLKRSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 KIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 QEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 HSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 MVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKSLE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 TRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFLAEHKYPTLPGKLSGATPNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFLAEHKYPTLPGKLSGATPNGE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 AAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWDDTAVVNDLSSTSSGTESGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWDDTAVVNDLSSTSSGTESGPQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 SPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSRTRDSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSRTRDSKG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 QKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKELGIKHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKELGIKHP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 LHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTV ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_006 LHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDRRMLQYLTV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 NDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEW 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 LRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 PEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPMEPSDGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPMEPSDGVS 730 740 750 760 770 780 790 800 810 pF1KB1 DSHRVYSGYRGLSPLDAPELDGLDQVGQIS :::::::::::::::::::::::::. XP_006 DSHRVYSGYRGLSPLDAPELDGLDQMAPSEGTVTQIGLLSQDIHRLTTMLSQDQLLNDSR 790 800 810 820 830 840 >>XP_006718413 (OMIM: 603142) PREDICTED: liprin-beta-2 i (887 aa) initn: 5246 init1: 5246 opt: 5249 Z-score: 2739.8 bits: 518.0 E(85289): 7.2e-146 Smith-Waterman score: 5249; 99.2% identity (99.6% similar) in 800 aa overlap (13-810:88-887) 10 20 30 40 pF1KB1 MDGDIDVYKHFSWLKRS--QVNHHSAASNETYQERLARLEGD :...: ::::::::::::::::::::::: XP_006 RLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGD 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB1 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL 120 130 140 150 160 170 110 120 130 140 150 160 pF1KB1 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK 180 190 200 210 220 230 170 180 190 200 210 220 pF1KB1 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD 240 250 260 270 280 290 230 240 250 260 270 280 pF1KB1 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM 300 310 320 330 340 350 290 300 310 320 330 340 pF1KB1 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL 360 370 380 390 400 410 350 360 370 380 390 400 pF1KB1 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD 420 430 440 450 460 470 410 420 430 440 450 460 pF1KB1 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR 480 490 500 510 520 530 470 480 490 500 510 520 pF1KB1 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG 540 550 560 570 580 590 530 540 550 560 570 580 pF1KB1 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ 600 610 620 630 640 650 590 600 610 620 630 640 pF1KB1 YKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YKDQFHESRVDRRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD 660 670 680 690 700 710 650 660 670 680 690 700 pF1KB1 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI 720 730 740 750 760 770 710 720 730 740 750 760 pF1KB1 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK 780 790 800 810 820 830 770 780 790 800 810 pF1KB1 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS :::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS 840 850 860 870 880 >>XP_011518718 (OMIM: 603142) PREDICTED: liprin-beta-2 i (897 aa) initn: 5277 init1: 5217 opt: 5220 Z-score: 2724.8 bits: 515.2 E(85289): 5e-145 Smith-Waterman score: 5220; 99.1% identity (99.6% similar) in 796 aa overlap (13-806:88-883) 10 20 30 40 pF1KB1 MDGDIDVYKHFSWLKRS--QVNHHSAASNETYQERLARLEGD :...: ::::::::::::::::::::::: XP_011 RLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGD 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB1 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL 120 130 140 150 160 170 110 120 130 140 150 160 pF1KB1 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK 180 190 200 210 220 230 170 180 190 200 210 220 pF1KB1 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD 240 250 260 270 280 290 230 240 250 260 270 280 pF1KB1 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM 300 310 320 330 340 350 290 300 310 320 330 340 pF1KB1 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL 360 370 380 390 400 410 350 360 370 380 390 400 pF1KB1 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD 420 430 440 450 460 470 410 420 430 440 450 460 pF1KB1 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR 480 490 500 510 520 530 470 480 490 500 510 520 pF1KB1 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG 540 550 560 570 580 590 530 540 550 560 570 580 pF1KB1 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ 600 610 620 630 640 650 590 600 610 620 630 640 pF1KB1 YKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKDQFHESRVDRRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD 660 670 680 690 700 710 650 660 670 680 690 700 pF1KB1 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI 720 730 740 750 760 770 710 720 730 740 750 760 pF1KB1 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK 780 790 800 810 820 830 770 780 790 800 810 pF1KB1 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS :::::::::::::::::::::::::::::::::::::::::::::. XP_011 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQMAPSEDNAEPGPAAE 840 850 860 870 880 890 >>XP_011518716 (OMIM: 603142) PREDICTED: liprin-beta-2 i (927 aa) initn: 5277 init1: 5217 opt: 5220 Z-score: 2724.5 bits: 515.2 E(85289): 5.1e-145 Smith-Waterman score: 5220; 99.1% identity (99.6% similar) in 796 aa overlap (13-806:88-883) 10 20 30 40 pF1KB1 MDGDIDVYKHFSWLKRS--QVNHHSAASNETYQERLARLEGD :...: ::::::::::::::::::::::: XP_011 RLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGD 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB1 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL 120 130 140 150 160 170 110 120 130 140 150 160 pF1KB1 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK 180 190 200 210 220 230 170 180 190 200 210 220 pF1KB1 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD 240 250 260 270 280 290 230 240 250 260 270 280 pF1KB1 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM 300 310 320 330 340 350 290 300 310 320 330 340 pF1KB1 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL 360 370 380 390 400 410 350 360 370 380 390 400 pF1KB1 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD 420 430 440 450 460 470 410 420 430 440 450 460 pF1KB1 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR 480 490 500 510 520 530 470 480 490 500 510 520 pF1KB1 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG 540 550 560 570 580 590 530 540 550 560 570 580 pF1KB1 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ 600 610 620 630 640 650 590 600 610 620 630 640 pF1KB1 YKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKDQFHESRVDRRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD 660 670 680 690 700 710 650 660 670 680 690 700 pF1KB1 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI 720 730 740 750 760 770 710 720 730 740 750 760 pF1KB1 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK 780 790 800 810 820 830 770 780 790 800 810 pF1KB1 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS :::::::::::::::::::::::::::::::::::::::::::::. XP_011 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQMAPSEGTVTQIGLLS 840 850 860 870 880 890 XP_011 QDIHRLTTMLSQDQLLNDSRLPAPNSDDWR 900 910 920 >>XP_006718412 (OMIM: 603142) PREDICTED: liprin-beta-2 i (927 aa) initn: 5277 init1: 5217 opt: 5220 Z-score: 2724.5 bits: 515.2 E(85289): 5.1e-145 Smith-Waterman score: 5220; 99.1% identity (99.6% similar) in 796 aa overlap (13-806:88-883) 10 20 30 40 pF1KB1 MDGDIDVYKHFSWLKRS--QVNHHSAASNETYQERLARLEGD :...: ::::::::::::::::::::::: XP_006 RLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGD 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB1 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL 120 130 140 150 160 170 110 120 130 140 150 160 pF1KB1 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK 180 190 200 210 220 230 170 180 190 200 210 220 pF1KB1 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD 240 250 260 270 280 290 230 240 250 260 270 280 pF1KB1 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM 300 310 320 330 340 350 290 300 310 320 330 340 pF1KB1 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL 360 370 380 390 400 410 350 360 370 380 390 400 pF1KB1 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD 420 430 440 450 460 470 410 420 430 440 450 460 pF1KB1 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR 480 490 500 510 520 530 470 480 490 500 510 520 pF1KB1 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG 540 550 560 570 580 590 530 540 550 560 570 580 pF1KB1 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ 600 610 620 630 640 650 590 600 610 620 630 640 pF1KB1 YKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YKDQFHESRVDRRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD 660 670 680 690 700 710 650 660 670 680 690 700 pF1KB1 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI 720 730 740 750 760 770 710 720 730 740 750 760 pF1KB1 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK 780 790 800 810 820 830 770 780 790 800 810 pF1KB1 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS :::::::::::::::::::::::::::::::::::::::::::::. XP_006 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQMAPSEGTVTQIGLLS 840 850 860 870 880 890 XP_006 QDIHRLTTMLSQDQLLNDSRLPAPNSDDWR 900 910 920 >>XP_011518715 (OMIM: 603142) PREDICTED: liprin-beta-2 i (927 aa) initn: 5277 init1: 5217 opt: 5220 Z-score: 2724.5 bits: 515.2 E(85289): 5.1e-145 Smith-Waterman score: 5220; 99.1% identity (99.6% similar) in 796 aa overlap (13-806:88-883) 10 20 30 40 pF1KB1 MDGDIDVYKHFSWLKRS--QVNHHSAASNETYQERLARLEGD :...: ::::::::::::::::::::::: XP_011 RLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGD 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB1 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL 120 130 140 150 160 170 110 120 130 140 150 160 pF1KB1 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK 180 190 200 210 220 230 170 180 190 200 210 220 pF1KB1 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD 240 250 260 270 280 290 230 240 250 260 270 280 pF1KB1 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM 300 310 320 330 340 350 290 300 310 320 330 340 pF1KB1 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL 360 370 380 390 400 410 350 360 370 380 390 400 pF1KB1 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD 420 430 440 450 460 470 410 420 430 440 450 460 pF1KB1 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR 480 490 500 510 520 530 470 480 490 500 510 520 pF1KB1 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG 540 550 560 570 580 590 530 540 550 560 570 580 pF1KB1 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ 600 610 620 630 640 650 590 600 610 620 630 640 pF1KB1 YKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKDQFHESRVDRRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD 660 670 680 690 700 710 650 660 670 680 690 700 pF1KB1 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI 720 730 740 750 760 770 710 720 730 740 750 760 pF1KB1 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK 780 790 800 810 820 830 770 780 790 800 810 pF1KB1 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS :::::::::::::::::::::::::::::::::::::::::::::. XP_011 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQMAPSEGTVTQIGLLS 840 850 860 870 880 890 XP_011 QDIHRLTTMLSQDQLLNDSRLPAPNSDDWR 900 910 920 >>XP_011518717 (OMIM: 603142) PREDICTED: liprin-beta-2 i (900 aa) initn: 5216 init1: 5216 opt: 5219 Z-score: 2724.2 bits: 515.1 E(85289): 5.3e-145 Smith-Waterman score: 5219; 99.2% identity (99.6% similar) in 795 aa overlap (13-805:88-882) 10 20 30 40 pF1KB1 MDGDIDVYKHFSWLKRS--QVNHHSAASNETYQERLARLEGD :...: ::::::::::::::::::::::: XP_011 RLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGD 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB1 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDL 120 130 140 150 160 170 110 120 130 140 150 160 pF1KB1 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK 180 190 200 210 220 230 170 180 190 200 210 220 pF1KB1 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKD 240 250 260 270 280 290 230 240 250 260 270 280 pF1KB1 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEM 300 310 320 330 340 350 290 300 310 320 330 340 pF1KB1 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFL 360 370 380 390 400 410 350 360 370 380 390 400 pF1KB1 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWD 420 430 440 450 460 470 410 420 430 440 450 460 pF1KB1 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFR 480 490 500 510 520 530 470 480 490 500 510 520 pF1KB1 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSG 540 550 560 570 580 590 530 540 550 560 570 580 pF1KB1 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQ 600 610 620 630 640 650 590 600 610 620 630 640 pF1KB1 YKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKDQFHESRVDRRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPAD 660 670 680 690 700 710 650 660 670 680 690 700 pF1KB1 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNI 720 730 740 750 760 770 710 720 730 740 750 760 pF1KB1 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRK 780 790 800 810 820 830 770 780 790 800 810 pF1KB1 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS ::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQKRSNTEKAPPGPSSC 840 850 860 870 880 890 XP_011 SLD 900 >>XP_011518719 (OMIM: 603142) PREDICTED: liprin-beta-2 i (858 aa) initn: 5277 init1: 5217 opt: 5217 Z-score: 2723.5 bits: 514.9 E(85289): 5.8e-145 Smith-Waterman score: 5217; 99.7% identity (99.9% similar) in 790 aa overlap (17-806:25-814) 10 20 30 40 50 pF1KB1 MDGDIDVYKHFSWLKRSQVNHHSAASNETYQERLARLEGDKESLILQVSVLT :::::::::::::::::::::::::::::::::::: XP_011 MWLSTVMADRGGQRLGSRRTVKATSQVNHHSAASNETYQERLARLEGDKESLILQVSVLT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB1 DQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB1 GMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVAL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB1 KDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB1 YRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPP 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB1 PLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFLAEHKYPTLPGKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFLAEHKYPTLPGKL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB1 SGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWDDTAVVNDLSSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGATPNGEAAKSPPTICQPDATGSSLLRLNRGRSVSAPVLGDTESGWDDTAVVNDLSSTS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB1 SGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB1 SRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDME 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB1 KELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDR 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB1 RMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQW 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB1 SNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLT 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB1 TKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICP 730 740 750 760 770 780 780 790 800 810 pF1KB1 MEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS :::::::::::::::::::::::::::::::::. XP_011 MEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQMAPSEGTVTQIGLLSQDIHRLTTMLSQ 790 800 810 820 830 840 XP_011 DQLLNDSRLPAPNSDDWR 850 >>XP_011518720 (OMIM: 603142) PREDICTED: liprin-beta-2 i (815 aa) initn: 5126 init1: 5024 opt: 5026 Z-score: 2624.9 bits: 496.6 E(85289): 1.8e-139 Smith-Waterman score: 5026; 99.6% identity (99.9% similar) in 760 aa overlap (47-806:12-771) 20 30 40 50 60 70 pF1KB1 SQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKL .::::::::::::::::::::::::::::: XP_011 MSSEQWPRLPGKVSVLTDQVEAQGEKIRDLEVCLEGHQVKL 10 20 30 40 80 90 100 110 120 130 pF1KB1 NAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELR 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB1 HLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHT 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB1 ERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEE 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB1 EPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRS 230 240 250 260 270 280 320 330 340 350 360 370 pF1KB1 ESVDKCMDGNQPFPVLEPKDSPFLAEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESVDKCMDGNQPFPVLEPKDSPFLAEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGS 290 300 310 320 330 340 380 390 400 410 420 430 pF1KB1 SLLRLNRGRSVSAPVLGDTESGWDDTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLRLNRGRSVSAPVLGDTESGWDDTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKK 350 360 370 380 390 400 440 450 460 470 480 490 pF1KB1 FWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTER 410 420 430 440 450 460 500 510 520 530 540 550 pF1KB1 VCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTK 470 480 490 500 510 520 560 570 580 590 600 610 pF1KB1 QEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLS ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: XP_011 QEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDRRMLQYLTVNDLLFLKVTSQLHHLS 530 540 550 560 570 580 620 630 640 650 660 670 pF1KB1 IKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGS 590 600 610 620 630 640 680 690 700 710 720 730 pF1KB1 GVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAY 650 660 670 680 690 700 740 750 760 770 780 790 pF1KB1 TPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLD 710 720 730 740 750 760 800 810 pF1KB1 APELDGLDQVGQIS :::::::::. XP_011 APELDGLDQMAPSEGTVTQIGLLSQDIHRLTTMLSQDQLLNDSRLPAPNSDDWR 770 780 790 800 810 810 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:52:39 2016 done: Thu Nov 3 11:52:41 2016 Total Scan time: 13.280 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]