FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB1440, 1898 aa 1>>>pF1KB1440 1898 - 1898 aa - 1898 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.2492+/-0.00064; mu= -2.0992+/- 0.040 mean_var=312.5558+/-61.070, 0's: 0 Z-trim(113.2): 912 B-trim: 33 in 1/57 Lambda= 0.072545 statistics sampled from 21383 (22457) to 21383 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.263), width: 16 Scan time: 21.690 The best scores are: opt bits E(85289) NP_569707 (OMIM: 179590,616001) receptor-type tyro (1898) 12718 1347.7 0 XP_006710861 (OMIM: 179590,616001) PREDICTED: rece (1902) 12700 1345.9 0 XP_016870470 (OMIM: 601598) PREDICTED: receptor-ty (1890) 9074 966.4 0 XP_006716890 (OMIM: 601598) PREDICTED: receptor-ty (1893) 9045 963.3 0 XP_005271138 (OMIM: 179590,616001) PREDICTED: rece (1909) 8761 933.6 0 XP_006710859 (OMIM: 179590,616001) PREDICTED: rece (1913) 8743 931.7 0 XP_016857433 (OMIM: 179590,616001) PREDICTED: rece (1800) 8458 901.9 0 XP_005271139 (OMIM: 179590,616001) PREDICTED: rece (1796) 8445 900.5 0 XP_016870469 (OMIM: 601598) PREDICTED: receptor-ty (1903) 8189 873.7 0 NP_002831 (OMIM: 179590,616001) receptor-type tyro (1907) 7564 808.3 0 XP_006710860 (OMIM: 179590,616001) PREDICTED: rece (1911) 7564 808.3 0 XP_005259664 (OMIM: 601576) PREDICTED: receptor-ty (1906) 7409 792.1 0 NP_001316069 (OMIM: 179590,616001) receptor-type t (1603) 6582 705.5 1.1e-201 XP_016882561 (OMIM: 601576) PREDICTED: receptor-ty (1910) 6274 673.3 6.4e-192 NP_002830 (OMIM: 601598) receptor-type tyrosine-pr (1912) 5573 599.9 7.8e-170 XP_011516294 (OMIM: 601598) PREDICTED: receptor-ty (1912) 5573 599.9 7.8e-170 XP_006716886 (OMIM: 601598) PREDICTED: receptor-ty (1913) 5561 598.7 1.9e-169 XP_006716888 (OMIM: 601598) PREDICTED: receptor-ty (1912) 5550 597.5 4.1e-169 XP_016870467 (OMIM: 601598) PREDICTED: receptor-ty (1917) 5543 596.8 6.9e-169 XP_016870465 (OMIM: 601598) PREDICTED: receptor-ty (1918) 5541 596.6 7.9e-169 XP_016870468 (OMIM: 601598) PREDICTED: receptor-ty (1916) 5532 595.6 1.5e-168 XP_005271137 (OMIM: 179590,616001) PREDICTED: rece (1918) 5171 557.9 3.6e-157 XP_016882560 (OMIM: 601576) PREDICTED: receptor-ty (1919) 4925 532.1 2e-149 NP_569077 (OMIM: 601598) receptor-type tyrosine-pr (1496) 4890 528.4 2.1e-148 XP_006716900 (OMIM: 601598) PREDICTED: receptor-ty (1496) 4890 528.4 2.1e-148 XP_016870482 (OMIM: 601598) PREDICTED: receptor-ty (1502) 4890 528.4 2.1e-148 XP_016870483 (OMIM: 601598) PREDICTED: receptor-ty (1501) 4889 528.3 2.3e-148 XP_016870481 (OMIM: 601598) PREDICTED: receptor-ty (1503) 4876 526.9 5.9e-148 XP_016870479 (OMIM: 601598) PREDICTED: receptor-ty (1506) 4876 526.9 5.9e-148 NP_001035802 (OMIM: 601598) receptor-type tyrosine (1502) 4875 526.8 6.4e-148 XP_006716898 (OMIM: 601598) PREDICTED: receptor-ty (1502) 4875 526.8 6.4e-148 XP_006716896 (OMIM: 601598) PREDICTED: receptor-ty (1505) 4875 526.8 6.4e-148 NP_569075 (OMIM: 601598) receptor-type tyrosine-pr (1505) 4875 526.8 6.4e-148 XP_016870478 (OMIM: 601598) PREDICTED: receptor-ty (1507) 4874 526.7 6.9e-148 XP_016870480 (OMIM: 601598) PREDICTED: receptor-ty (1506) 4873 526.6 7.4e-148 NP_569076 (OMIM: 601598) receptor-type tyrosine-pr (1506) 4873 526.6 7.4e-148 XP_006716902 (OMIM: 601598) PREDICTED: receptor-ty (1491) 4864 525.6 1.4e-147 XP_006716901 (OMIM: 601598) PREDICTED: receptor-ty (1495) 4864 525.6 1.4e-147 XP_016870484 (OMIM: 601598) PREDICTED: receptor-ty (1501) 4864 525.6 1.4e-147 NP_570923 (OMIM: 601576) receptor-type tyrosine-pr (1501) 4761 514.9 2.5e-144 XP_005259666 (OMIM: 601576) PREDICTED: receptor-ty (1501) 4761 514.9 2.5e-144 XP_016882565 (OMIM: 601576) PREDICTED: receptor-ty (1505) 4761 514.9 2.5e-144 NP_570925 (OMIM: 601576) receptor-type tyrosine-pr (1505) 4761 514.9 2.5e-144 XP_005259667 (OMIM: 601576) PREDICTED: receptor-ty (1497) 4757 514.4 3.3e-144 XP_005259663 (OMIM: 601576) PREDICTED: receptor-ty (1910) 4592 497.3 6.3e-139 NP_570924 (OMIM: 601576) receptor-type tyrosine-pr (1910) 4592 497.3 6.3e-139 XP_016882559 (OMIM: 601576) PREDICTED: receptor-ty (1923) 4592 497.3 6.3e-139 XP_006710863 (OMIM: 179590,616001) PREDICTED: rece (1811) 4501 487.7 4.4e-136 XP_016857434 (OMIM: 179590,616001) PREDICTED: rece (1807) 4406 477.8 4.4e-133 XP_016857432 (OMIM: 179590,616001) PREDICTED: rece (1816) 4327 469.5 1.4e-130 >>NP_569707 (OMIM: 179590,616001) receptor-type tyrosine (1898 aa) initn: 12718 init1: 12718 opt: 12718 Z-score: 7211.6 bits: 1347.7 E(85289): 0 Smith-Waterman score: 12718; 100.0% identity (100.0% similar) in 1898 aa overlap (1-1898:1-1898) 10 20 30 40 50 60 pF1KB1 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB1 ETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 ETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB1 LLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 LLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIR 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB1 TPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 TPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB1 DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB1 LSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 LSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQH 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB1 LVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGSMLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 LVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGSMLTP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB1 RWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKNYRGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 RWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKNYRGF 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB1 YNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 YNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB1 AVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 AVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDH 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB1 PPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 PPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDH 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB1 SRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 SRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB1 TRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 TRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQF 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB1 QFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 QFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB1 HEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 HEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQ 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB1 VPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 VPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGV 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB1 EGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 EGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKC 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB1 HQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 HQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVP 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB1 KTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_569 KTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQ 1810 1820 1830 1840 1850 1860 1870 1880 1890 pF1KB1 TVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT :::::::::::::::::::::::::::::::::::::: NP_569 TVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1870 1880 1890 >>XP_006710861 (OMIM: 179590,616001) PREDICTED: receptor (1902 aa) initn: 11217 init1: 11217 opt: 12700 Z-score: 7201.4 bits: 1345.9 E(85289): 0 Smith-Waterman score: 12700; 99.8% identity (99.8% similar) in 1902 aa overlap (1-1898:1-1902) 10 20 30 40 50 60 pF1KB1 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS 130 140 150 160 170 180 190 200 210 220 230 pF1KB1 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSI :::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_006 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRDQREVRRVAPRFSI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB1 PPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANY 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB1 TCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB1 AGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB1 PRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB1 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB1 QERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB1 IEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGR 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB1 HVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVE 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB1 VEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTIS 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB1 GLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKE 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB1 LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFE 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB1 KEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQ 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB1 NITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMK 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB1 TSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB1 GLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGS 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB1 MLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKN 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB1 YRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVT 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB1 GPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB1 MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVI 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB1 AYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTAT 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB1 VVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRE 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB1 LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAML 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KB1 ERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQ 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KB1 KLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQP 1630 1640 1650 1660 1670 1680 1680 1690 1700 1710 1720 1730 pF1KB1 IRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMG 1690 1700 1710 1720 1730 1740 1740 1750 1760 1770 1780 1790 pF1KB1 REKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 REKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPE 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KB1 QGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVV 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 pF1KB1 DMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT :::::::::::::::::::::::::::::::::::::::::: XP_006 DMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1870 1880 1890 1900 >>XP_016870470 (OMIM: 601598) PREDICTED: receptor-type t (1890 aa) initn: 7158 init1: 3926 opt: 9074 Z-score: 5150.4 bits: 966.4 E(85289): 0 Smith-Waterman score: 9074; 70.7% identity (87.4% similar) in 1889 aa overlap (18-1898:9-1890) 10 20 30 40 50 60 pF1KB1 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP :..: . . ... : : ..: ::::.:::::::.:::::.: XP_016 MVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDP 10 20 30 40 50 70 80 90 100 110 120 pF1KB1 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA .:.:.: :::::::.:::::::::::.::::::::::. ::::::::.:.:..:::..:. XP_016 RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVST 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB1 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS .:.::.:.:.: :::.:::::::::::..:::::::::.:::::::.::::::::: ... XP_016 RLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNN 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB1 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS :::::::::::::::.:::::::::::::::::::::::::::::::::: :::::::.. XP_016 NGRIKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTN 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB1 QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA .:.:::::::.::::::.::::::::.:::.:: ::.::.:::::::..: .:::::::: XP_016 HEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVA 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB1 ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE .:.::.::: ::.::::::::: ::::.::::.:::::::: :::.:: ::.. ..: XP_016 MSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB1 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV ..:.:::::::::..::::.:.: :::.:::.:::::::: : ..:.:::::: :: : XP_016 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB1 QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLP ::::::..:.::::. :::::: ..::::::: : . : : :::. . .::.:.:.: XP_016 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVP 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB1 GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI :::..:::::..:::: : ::: :: :::.:: .:.:: ::.: : ::: : .. : XP_016 QKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTI 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB1 IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR ::::: .: ..: ..:..: .:: :. :::..:: :.::::: .:.:. : : :: XP_016 ANYELVYKDGEHGEEQ-RITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISAR 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB1 TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD : :: :::::: . :.: .::.. ::: :::....::.::.::. : :::::: : . XP_016 TMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEIL 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB1 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL :: . ... : ::::::::. : ::::::::::: ::.::.:::::::::::::: . XP_016 GIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAV 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB1 NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTP :::.:.: :. :::.::::::::::: :::.:::::.: :...:::::.::. :::: : XP_016 NSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISGLQP 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB1 ETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGE ::.::.::.::::::::::::::.:.:::::::.: ..:. : :::::.::::: . : XP_016 ETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGP 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB1 LLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIR : ::::.. : : .:..:.. ..:::.: .:::..:.:::.:.:..:.:::. ::: XP_016 LQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEIS 840 850 860 870 880 890 910 920 930 940 950 pF1KB1 TPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQ---QELQN ::..:.::::::: : :.....:.:.::::::::: : .::...:::: .: XP_016 IPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLI 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KB1 ITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKT . .:: .::::::::::::.:::: :::: :: :::.: ::.::.:::::::.: :.::: XP_016 VPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKT 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KB1 SVLLSWEVPDSYKSAVPFKILYN-GQSVE-VDGHSMRKLIADLQPNTEYSFVLMNRGSSA :::::::.:..:.::.::::::. :. :: :::.. .:::..:.:. ::::: :::.:: XP_016 SVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSA 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KB1 GGLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGG ::::: :. .::::.: :: . :: . ...:.: .. .::..::. . : XP_016 GGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKSRG 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KB1 SMLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKK ... : : .:.:.::::::. : . ... : :..: ::::.::..:::: ::::: : XP_016 KFIKP-WESPDEMELDELLKEISRK-RRSIRYGREVE-LKPYIAAHFDVLPTEFTLGDDK 1140 1150 1160 1170 1180 1200 1210 1220 1230 1240 1250 pF1KB1 NYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIV-VQVTPAQQQEEPE-ML .: :: :. :. : :::: . : ..: ::.::::: .: ... : .: : .. XP_016 HYGGFTNKQLQSGQEYVFFVLAVM-EHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLI 1190 1200 1210 1220 1230 1240 1260 1270 1280 1290 1300 1310 pF1KB1 WVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSI-GLKDSLLAHSSDPVEMRRLNY ::.::::::..:: :::::::.::::..: : : .:: . :. : .::::.::::. XP_016 WVVGPVLAVVFIICIVIAILLYKRKRAESDSRK--SSIPNNKEIPSHHPTDPVELRRLNF 1250 1260 1270 1280 1290 1300 1320 1330 1340 1350 1360 1370 pF1KB1 QTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRY ::::: .:::::: .:::.::::::::.:::::::::::::::::::.:::::::::::: XP_016 QTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRY 1310 1320 1330 1340 1350 1360 1380 1390 1400 1410 1420 1430 pF1KB1 ANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQ :::::::::::.:..:.:.:::::.::::::::::::::::::: ::::.::::::.::: XP_016 ANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQ 1370 1380 1390 1400 1410 1420 1440 1450 1460 1470 1480 1490 pF1KB1 RTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSS :.:::::::.:::.::::::::::.::::: ::.::::::::::::: ::::::.:.::: XP_016 RSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSS 1430 1440 1450 1460 1470 1480 1500 1510 1520 1530 1540 1550 pF1KB1 EKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVI ::::.::::: :::::::::.:::.::::::::.::: :::::::::::::::::::::: XP_016 EKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVI 1490 1500 1510 1520 1530 1540 1560 1570 1580 1590 1600 1610 pF1KB1 DAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLY ::::::.::::::::::::: ::.::::::::::::.:::.:::::.:::.::::::::: XP_016 DAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLY 1550 1560 1570 1580 1590 1600 1620 1630 1640 1650 1660 1670 pF1KB1 AHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRV :.:::: :. ::.::.:::::: :::::::::::::::::::::::::::::::: ::: XP_016 AYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRV 1610 1620 1630 1640 1650 1660 1680 1690 1700 1710 1720 1730 pF1KB1 CLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKL ::::::::::::::::::.::::::::::::::::::.:::::::::::::::.:::::: XP_016 CLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKL 1670 1680 1690 1700 1710 1720 1740 1750 1760 1770 1780 1790 pF1KB1 REMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFT :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: XP_016 REMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFT 1730 1740 1750 1760 1770 1780 1800 1810 1820 1830 1840 1850 pF1KB1 DWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRY :::::::::.::::::::::::::::::::::::.::::::::::::::::::::::::: XP_016 DWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRY 1790 1800 1810 1820 1830 1840 1860 1870 1880 1890 pF1KB1 EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT :::::.::::: ::::::::::::::::. :::::::::::::::: XP_016 EGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT 1850 1860 1870 1880 1890 >>XP_006716890 (OMIM: 601598) PREDICTED: receptor-type t (1893 aa) initn: 6898 init1: 3936 opt: 9045 Z-score: 5134.0 bits: 963.3 E(85289): 0 Smith-Waterman score: 9045; 70.5% identity (87.2% similar) in 1893 aa overlap (18-1898:9-1893) 10 20 30 40 50 60 pF1KB1 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP :..: . . ... : : ..: ::::.:::::::.:::::.: XP_006 MVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDP 10 20 30 40 50 70 80 90 100 110 120 pF1KB1 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA .:.:.: :::::::.:::::::::::.::::::::::. ::::::::.:.:..:::..:. XP_006 RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVST 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB1 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS .:.::.:.:.: :::.:::::::::::..:::::::::.:::::::.::::::::: ... XP_006 RLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNN 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB1 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS :::::::::::::::.:::::::::::::::::::::::::::::::::: :::::::.. XP_006 NGRIKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTN 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB1 QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA .:.:::::::.::::::.::::::::.:::.:: ::.::.:::::::..: .:::::::: XP_006 HEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVA 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB1 ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE .:.::.::: ::.::::::::: ::::.::::.:::::::: :::.:: ::.. ..: XP_006 MSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB1 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV ..:.:::::::::..::::.:.: :::.:::.:::::::: : ..:.:::::: :: : XP_006 ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDV 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB1 QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLP ::::::..:.::::. :::::: ..::::::: : . : : :::. . .::.:.:.: XP_006 QARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVP 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB1 GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI :::..:::::..:::: : ::: :: :::.:: .:.:: ::.: : ::: : .. : XP_006 QKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTI 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB1 IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR ::::: .: ..: ..:..: .:: :. :::..:: :.::::: .:.:. : : :: XP_006 ANYELVYKDGEHGEEQ-RITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISAR 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB1 TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD : :: :::::: . :.: .::.. ::: :::....::.::.::. : :::::: : . XP_006 TMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEIL 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB1 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL :: . ... : ::::::::. : ::::::::::: ::.::.:::::::::::::: . XP_006 GIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAV 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB1 NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTP :::.:.: :. :::.::::::::::: :::.:::::.: :...:::::.::. :::: : XP_006 NSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISGLQP 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB1 ETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGE ::.::.::.::::::::::::::.:.:::::::.: ..:. : :::::.::::: . : XP_006 ETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGP 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB1 LLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIR : ::::.. : : .:..:.. ..:::.: .:::..:.:::.:.:..:.:::. ::: XP_006 LQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEIS 840 850 860 870 880 890 910 920 930 940 950 pF1KB1 TPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQ---QELQN ::..:.::::::: : :.....:.:.::::::::: : .::...:::: .: XP_006 IPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLI 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KB1 ITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKT . .:: .::::::::::::.:::: :::: :: :::.: ::.::.:::::::.: :.::: XP_006 VPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKT 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KB1 SVLLSWEVPDSYKSAVPFKILYN-GQSVE-VDGHSMRKLIADLQPNTEYSFVLMNRGSSA :::::::.:..:.::.::::::. :. :: :::.. .:::..:.:. ::::: :::.:: XP_006 SVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSA 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KB1 GGLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGG ::::: :. .::::.: :: . :: . ...:.: .. .::..::. . : XP_006 GGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKSRG 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KB1 SMLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKK ... : : .:.:.::::::. : . ... : :..: ::::.::..:::: ::::: : XP_006 KFIKP-WESPDEMELDELLKEISRK-RRSIRYGREVE-LKPYIAAHFDVLPTEFTLGDDK 1140 1150 1160 1170 1180 1200 1210 1220 1230 1240 1250 pF1KB1 NYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIV-VQVTPAQQQEEPE-ML .: :: :. :. : :::: ... .. ::.::::: .: ... : .: : .. XP_006 HYGGFTNKQLQSGQEYVFFVLAVMEHA--ESMYATSPYSDPVVSMDLDPQPITDEEEGLI 1190 1200 1210 1220 1230 1240 1260 1270 1280 1290 1300 pF1KB1 WVTGPVLAVILIILIVIAILLFK----RKRTHSPSSKDEQSI-GLKDSLLAHSSDPVEMR ::.::::::..:: :::::::.: :::..: : : .:: . :. : .::::.: XP_006 WVVGPVLAVVFIICIVIAILLYKSKPDRKRAESDSRK--SSIPNNKEIPSHHPTDPVELR 1250 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 pF1KB1 RLNYQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKP :::.::::: .:::::: .:::.::::::::.:::::::::::::::::::.:::::::: XP_006 RLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKP 1310 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 pF1KB1 KNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRM :::::::::::::::.:..:.:.:::::.::::::::::::::::::: ::::.:::::: XP_006 KNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRM 1370 1380 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 pF1KB1 VWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHK .::::.:::::::.:::.::::::::::.::::: ::.::::::::::::: ::::::.: XP_006 IWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYK 1430 1440 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 pF1KB1 SGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGC .:::::::.::::: :::::::::.:::.::::::::.::: :::::::::::::::::: XP_006 NGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGC 1490 1500 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 pF1KB1 FIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPA ::::::::::.::::::::::::: ::.::::::::::::.:::.:::::.:::.::::: XP_006 FIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPA 1550 1560 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 pF1KB1 RNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYE :::::.:::: :. ::.::.:::::: :::::::::::::::::::::::::::::::: XP_006 RNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYE 1610 1620 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 pF1KB1 LTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVM :::::::::::::::::::::.::::::::::::::::::.:::::::::::::::.:: XP_006 STRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVM 1670 1680 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 pF1KB1 LTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: XP_006 LTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQ 1730 1740 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 pF1KB1 FQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLE :::::::::::::.::::::::::::::::::::::::.::::::::::::::::::::: XP_006 FQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLE 1790 1800 1810 1820 1830 1840 1850 1860 1870 1880 1890 pF1KB1 RMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT :::::::::.::::: ::::::::::::::::. :::::::::::::::: XP_006 RMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT 1850 1860 1870 1880 1890 >>XP_005271138 (OMIM: 179590,616001) PREDICTED: receptor (1909 aa) initn: 9488 init1: 8751 opt: 8761 Z-score: 4973.3 bits: 933.6 E(85289): 0 Smith-Waterman score: 12686; 99.4% identity (99.4% similar) in 1909 aa overlap (1-1898:1-1909) 10 20 30 40 50 60 pF1KB1 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB1 ETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB1 LLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIR 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB1 TPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB1 DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB1 LSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQH 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB1 LVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGSMLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGSMLTP 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB1 RWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKNYRGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKNYRGF 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB1 YNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KB1 AVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGSSVP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 pF1KB1 -------MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPK ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SCPNTSSMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPK 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KB1 NRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMV 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KB1 WEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKS 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KB1 GSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCF 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KB1 IVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPAR 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KB1 NLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYEL 1630 1640 1650 1660 1670 1680 1670 1680 1690 1700 1710 1720 pF1KB1 TRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVML 1690 1700 1710 1720 1730 1740 1730 1740 1750 1760 1770 1780 pF1KB1 TKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQF 1750 1760 1770 1780 1790 1800 1790 1800 1810 1820 1830 1840 pF1KB1 QFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLER 1810 1820 1830 1840 1850 1860 1850 1860 1870 1880 1890 pF1KB1 MRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1870 1880 1890 1900 >>XP_006710859 (OMIM: 179590,616001) PREDICTED: receptor (1913 aa) initn: 7987 init1: 7250 opt: 8743 Z-score: 4963.1 bits: 931.7 E(85289): 0 Smith-Waterman score: 12668; 99.2% identity (99.2% similar) in 1913 aa overlap (1-1898:1-1913) 10 20 30 40 50 60 pF1KB1 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS 130 140 150 160 170 180 190 200 210 220 230 pF1KB1 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSI :::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_006 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRDQREVRRVAPRFSI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB1 PPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANY 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB1 TCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB1 AGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB1 PRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB1 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB1 QERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB1 IEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGR 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB1 HVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVE 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB1 VEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTIS 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB1 GLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKE 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB1 LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFE 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB1 KEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQ 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB1 NITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMK 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB1 TSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB1 GLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGS 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB1 MLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKN 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB1 YRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVT 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB1 GPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 pF1KB1 -----------MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEV ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSVPSCPNTSSMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEV 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KB1 NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDF 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 1470 1480 pF1KB1 WRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFA 1450 1460 1470 1480 1490 1500 1490 1500 1510 1520 1530 1540 pF1KB1 LHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGR 1510 1520 1530 1540 1550 1560 1550 1560 1570 1580 1590 1600 pF1KB1 TGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTE 1570 1580 1590 1600 1610 1620 1610 1620 1630 1640 1650 1660 pF1KB1 VPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIM 1630 1640 1650 1660 1670 1680 1670 1680 1690 1700 1710 1720 pF1KB1 PYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTI 1690 1700 1710 1720 1730 1740 1730 1740 1750 1760 1770 1780 pF1KB1 IVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRT 1750 1760 1770 1780 1790 1800 1790 1800 1810 1820 1830 1840 pF1KB1 IRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSI 1810 1820 1830 1840 1850 1860 1850 1860 1870 1880 1890 pF1KB1 VLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1870 1880 1890 1900 1910 >>XP_016857433 (OMIM: 179590,616001) PREDICTED: receptor (1800 aa) initn: 9551 init1: 8059 opt: 8458 Z-score: 4802.3 bits: 901.9 E(85289): 0 Smith-Waterman score: 11772; 94.4% identity (94.4% similar) in 1902 aa overlap (1-1898:1-1800) 10 20 30 40 50 60 pF1KB1 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS 130 140 150 160 170 180 190 200 210 220 230 pF1KB1 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----VRRVAPRFSI :::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_016 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRDQREVRRVAPRFSI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB1 PPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANY 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB1 TCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB1 AGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB1 PRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB1 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB1 QERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB1 IEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGR :::::::: XP_016 IEARTAQS---------------------------------------------------- 660 670 680 690 700 710 pF1KB1 HVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVE .::::::::: XP_016 --------------------------------------------------MPSGPPRKVE 610 720 730 740 750 760 770 pF1KB1 VEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTIS 620 630 640 650 660 670 780 790 800 810 820 830 pF1KB1 GLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKE 680 690 700 710 720 730 840 850 860 870 880 890 pF1KB1 LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFE 740 750 760 770 780 790 900 910 920 930 940 950 pF1KB1 KEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQ 800 810 820 830 840 850 960 970 980 990 1000 1010 pF1KB1 NITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMK 860 870 880 890 900 910 1020 1030 1040 1050 1060 1070 pF1KB1 TSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAG 920 930 940 950 960 970 1080 1090 1100 1110 1120 1130 pF1KB1 GLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGS 980 990 1000 1010 1020 1030 1140 1150 1160 1170 1180 1190 pF1KB1 MLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKN 1040 1050 1060 1070 1080 1090 1200 1210 1220 1230 1240 1250 pF1KB1 YRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVT 1100 1110 1120 1130 1140 1150 1260 1270 1280 1290 1300 1310 pF1KB1 GPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPG 1160 1170 1180 1190 1200 1210 1320 1330 1340 1350 1360 1370 pF1KB1 MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVI 1220 1230 1240 1250 1260 1270 1380 1390 1400 1410 1420 1430 pF1KB1 AYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTAT 1280 1290 1300 1310 1320 1330 1440 1450 1460 1470 1480 1490 pF1KB1 VVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRE 1340 1350 1360 1370 1380 1390 1500 1510 1520 1530 1540 1550 pF1KB1 LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAML 1400 1410 1420 1430 1440 1450 1560 1570 1580 1590 1600 1610 pF1KB1 ERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQ 1460 1470 1480 1490 1500 1510 1620 1630 1640 1650 1660 1670 pF1KB1 KLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQP 1520 1530 1540 1550 1560 1570 1680 1690 1700 1710 1720 1730 pF1KB1 IRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMG 1580 1590 1600 1610 1620 1630 1740 1750 1760 1770 1780 1790 pF1KB1 REKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPE 1640 1650 1660 1670 1680 1690 1800 1810 1820 1830 1840 1850 pF1KB1 QGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVV 1700 1710 1720 1730 1740 1750 1860 1870 1880 1890 pF1KB1 DMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT :::::::::::::::::::::::::::::::::::::::::: XP_016 DMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1760 1770 1780 1790 1800 >>XP_005271139 (OMIM: 179590,616001) PREDICTED: receptor (1796 aa) initn: 8059 init1: 8059 opt: 8445 Z-score: 4794.9 bits: 900.5 E(85289): 0 Smith-Waterman score: 11790; 94.6% identity (94.6% similar) in 1898 aa overlap (1-1898:1-1796) 10 20 30 40 50 60 pF1KB1 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD :::: XP_005 TAQS-------------------------------------------------------- 670 680 690 700 710 720 pF1KB1 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL .::::::::::::: XP_005 ----------------------------------------------MPSGPPRKVEVEPL 610 730 740 750 760 770 780 pF1KB1 NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTP 620 630 640 650 660 670 790 800 810 820 830 840 pF1KB1 ETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGE 680 690 700 710 720 730 850 860 870 880 890 900 pF1KB1 LLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIR 740 750 760 770 780 790 910 920 930 940 950 960 pF1KB1 TPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITT 800 810 820 830 840 850 970 980 990 1000 1010 1020 pF1KB1 DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVL 860 870 880 890 900 910 1030 1040 1050 1060 1070 1080 pF1KB1 LSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQH 920 930 940 950 960 970 1090 1100 1110 1120 1130 1140 pF1KB1 LVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGSMLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGSMLTP 980 990 1000 1010 1020 1030 1150 1160 1170 1180 1190 1200 pF1KB1 RWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKNYRGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKNYRGF 1040 1050 1060 1070 1080 1090 1210 1220 1230 1240 1250 1260 pF1KB1 YNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVL 1100 1110 1120 1130 1140 1150 1270 1280 1290 1300 1310 1320 pF1KB1 AVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDH 1160 1170 1180 1190 1200 1210 1330 1340 1350 1360 1370 1380 pF1KB1 PPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDH 1220 1230 1240 1250 1260 1270 1390 1400 1410 1420 1430 1440 pF1KB1 SRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM 1280 1290 1300 1310 1320 1330 1450 1460 1470 1480 1490 1500 pF1KB1 TRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQF 1340 1350 1360 1370 1380 1390 1510 1520 1530 1540 1550 1560 pF1KB1 QFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMK 1400 1410 1420 1430 1440 1450 1570 1580 1590 1600 1610 1620 pF1KB1 HEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQ 1460 1470 1480 1490 1500 1510 1630 1640 1650 1660 1670 1680 pF1KB1 VPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGV 1520 1530 1540 1550 1560 1570 1690 1700 1710 1720 1730 1740 pF1KB1 EGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKC 1580 1590 1600 1610 1620 1630 1750 1760 1770 1780 1790 1800 pF1KB1 HQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVP 1640 1650 1660 1670 1680 1690 1810 1820 1830 1840 1850 1860 pF1KB1 KTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQ 1700 1710 1720 1730 1740 1750 1870 1880 1890 pF1KB1 TVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT :::::::::::::::::::::::::::::::::::::: XP_005 TVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1760 1770 1780 1790 >>XP_016870469 (OMIM: 601598) PREDICTED: receptor-type t (1903 aa) initn: 7361 init1: 3926 opt: 8189 Z-score: 4649.8 bits: 873.7 E(85289): 0 Smith-Waterman score: 9028; 70.2% identity (86.8% similar) in 1902 aa overlap (18-1898:9-1903) 10 20 30 40 50 60 pF1KB1 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP :..: . . ... : : ..: ::::.:::::::.:::::.: XP_016 MVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDP 10 20 30 40 50 70 80 90 100 110 120 pF1KB1 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA .:.:.: :::::::.:::::::::::.::::::::::. ::::::::.:.:..:::..:. XP_016 RPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVST 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB1 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS .:.::.:.:.: :::.:::::::::::..:::::::::.:::::::.::::::::: ... XP_016 RLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNN 120 130 140 150 160 170 190 200 210 220 pF1KB1 NGRIKQLRS---------GALQIESSEESDQGKYECVATNSAGTRYSAPANLYVR----V ::::::::: ::::::.:::::::::::::::::::::::::::::: : XP_016 NGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREV 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB1 RRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLEL ::: :::::::...:.:::::::.::::::.::::::::.:::.:: ::.::.::::::: XP_016 RRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLEL 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB1 SNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPV ..: .::::::::.:.::.::: ::.::::::::: ::::.::::.:::::::: ::: XP_016 NDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPV 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB1 TYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRAR .:: ::.. ..: ..:.:::::::::..::::.:.: :::.:::.:::::::: : .. XP_016 SYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQ 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB1 TGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNT :.:::::: :: :::::::..:.::::. :::::: ..::::::: : . : : :::. XP_016 TSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV 420 430 440 450 460 470 470 480 490 500 510 520 pF1KB1 DAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTR . .::.:.:.: :::..:::::..:::: : ::: :: :::.:: .:.:: ::.: XP_016 ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETS 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB1 IQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSD : ::: : .. : ::::: .: ..: ..:..: .:: :. :::..:: :.::::: XP_016 ILLSWTPPRSDTIANYELVYKDGEHGEEQ-RITIEPGTSYRLQGLKPNSLYYFRLAARSP 540 550 560 570 580 590 590 600 610 620 630 640 pF1KB1 MGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYE .:.:. : : ::: :: :::::: . :.: .::.. ::: :::....::.::.::. : XP_016 QGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT 600 610 620 630 640 650 650 660 670 680 690 700 pF1KB1 AVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDV :::::: : . :: . ... : ::::::::. : ::::::::::: ::.::.::: XP_016 AVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDV 660 670 680 690 700 710 710 720 730 740 750 760 pF1KB1 PSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVML ::::::::::: .:::.:.: :. :::.::::::::::: :::.:::::.: :...:::: XP_016 PSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVML 720 730 740 750 760 770 770 780 790 800 810 820 pF1KB1 AEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTA :.::. :::: :::.::.::.::::::::::::::.:.:::::::.: ..:. : :::: XP_016 ADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTA 780 790 800 810 820 830 830 840 850 860 870 880 pF1KB1 LLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKN :.::::: . : : ::::.. : : .:..:.. ..:::.: .:::..:.:::.:.: XP_016 LIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARN 840 850 860 870 880 890 890 900 910 920 930 940 pF1KB1 RAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFR ..:.:::. ::: ::..:.::::::: : :.....:.:.::::::::: : .::...: XP_016 KVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYR 900 910 920 930 940 950 950 960 970 980 990 1000 pF1KB1 DINSQ---QELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQV ::: .: . .:: .::::::::::::.:::: :::: :: :::.: ::.::.:: XP_016 DINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQV 960 970 980 990 1000 1010 1010 1020 1030 1040 1050 1060 pF1KB1 FAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYN-GQSVE-VDGHSMRKLIADLQPNT :::::.: :.::::::::::.:..:.::.::::::. :. :: :::.. .:::..:.:. XP_016 FAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEK 1020 1030 1040 1050 1060 1070 1070 1080 1090 1100 1110 1120 pF1KB1 EYSFVLMNRGSSAGGLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRW ::::: :::.::::::: :. .::::.: :: . :: . ...:.: .. XP_016 SYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKG 1080 1090 1100 1110 1120 1130 1130 1140 1150 1160 1170 1180 pF1KB1 FYIVVVPIDRVGGSMLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQL .::..::. . :... : : .:.:.::::::. : . ... : :..: ::::.::.. XP_016 YYIIIVPLKKSRGKFIKP-WESPDEMELDELLKEISRK-RRSIRYGREVE-LKPYIAAHF 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 pF1KB1 DVLPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIV-VQV :::: ::::: :.: :: :. :. : :::: . : ..: ::.::::: .: ... XP_016 DVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVM-EHAESKMYATSPYSDPVVSMDL 1190 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 pF1KB1 TPAQQQEEPE-MLWVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSI-GLKDSLLA : .: : ..::.::::::..:: :::::::.::::..: : : .:: . :. XP_016 DPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESDSRK--SSIPNNKEIPSH 1250 1260 1270 1280 1290 1300 1300 1310 1320 1330 1340 1350 pF1KB1 HSSDPVEMRRLNYQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWE : .::::.::::.::::: .:::::: .:::.::::::::.::::::::::::::::::: XP_016 HPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWE 1310 1320 1330 1340 1350 1360 1360 1370 1380 1390 1400 1410 pF1KB1 NSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLP .:::::::::::::::::::::::.:..:.:.:::::.::::::::::::::::::: :: XP_016 HSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLP 1370 1380 1390 1400 1410 1420 1420 1430 1440 1450 1460 1470 pF1KB1 ETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATY ::.::::::.::::.:::::::.:::.::::::::::.::::: ::.::::::::::::: XP_016 ETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATY 1430 1440 1450 1460 1470 1480 1480 1490 1500 1510 1520 1530 pF1KB1 TVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHC ::::::.:.:::::::.::::: :::::::::.:::.::::::::.::: ::::::::: XP_016 CVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHC 1490 1500 1510 1520 1530 1540 1540 1550 1560 1570 1580 1590 pF1KB1 SAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAA :::::::::::::::::::.::::::::::::: ::.::::::::::::.:::.:::::. XP_016 SAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAV 1550 1560 1570 1580 1590 1600 1600 1610 1620 1630 1640 1650 pF1KB1 TCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKN :::.::::::::::.:::: :. ::.::.:::::: ::::::::::::::::::::::: XP_016 TCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKN 1610 1620 1630 1640 1650 1660 1660 1670 1680 1690 1700 1710 pF1KB1 RLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLW ::::::::: :::::::::::::::::::::.::::::::::::::::::.::::::::: XP_016 RLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLW 1670 1680 1690 1700 1710 1720 1720 1730 1740 1750 1760 1770 pF1KB1 EHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDAR ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDAR 1730 1740 1750 1760 1770 1780 1780 1790 1800 1810 1820 1830 pF1KB1 DGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGV ::::::.:::::::::::::::.::::::::::::::::::::::::.:::::::::::: XP_016 DGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGV 1790 1800 1810 1820 1830 1840 1840 1850 1860 1870 1880 1890 pF1KB1 FITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT ::::::::::::::::::.::::: ::::::::::::::::. :::::::::::::::: XP_016 FITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT 1850 1860 1870 1880 1890 1900 >>NP_002831 (OMIM: 179590,616001) receptor-type tyrosine (1907 aa) initn: 7561 init1: 7561 opt: 7564 Z-score: 4296.3 bits: 808.3 E(85289): 0 Smith-Waterman score: 12690; 99.5% identity (99.5% similar) in 1907 aa overlap (1-1898:1-1907) 10 20 30 40 50 60 pF1KB1 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEAR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL 670 680 690 700 710 720 730 740 750 760 770 pF1KB1 NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQ--------- ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDY 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB1 ETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQW 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB1 HPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGL 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB1 GEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB1 QQELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QQELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRV 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB1 AAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNR 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB1 GSSAGGLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GSSAGGLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPID 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB1 RVGGSMLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RVGGSMLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB1 GDKKNYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GDKKNYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPE 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB1 MLWVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MLWVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLN 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB1 YQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNR 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB1 YANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWE 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB1 QRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGS 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB1 SEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIV 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KB1 IDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNL 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KB1 YAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTR 1630 1640 1650 1660 1670 1680 1680 1690 1700 1710 1720 1730 pF1KB1 VCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTK 1690 1700 1710 1720 1730 1740 1740 1750 1760 1770 1780 1790 pF1KB1 LREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQF 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KB1 TDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMR 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 pF1KB1 YEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT ::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT 1870 1880 1890 1900 1898 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:54:07 2016 done: Thu Nov 3 11:54:11 2016 Total Scan time: 21.690 Total Display time: 1.830 Function used was FASTA [36.3.4 Apr, 2011]