FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB1487, 1913 aa 1>>>pF1KB1487 1913 - 1913 aa - 1913 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.0939+/-0.000613; mu= -4.0145+/- 0.038 mean_var=793.2764+/-168.683, 0's: 0 Z-trim(119.4): 1474 B-trim: 0 in 0/55 Lambda= 0.045537 statistics sampled from 31421 (33401) to 31421 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.392), width: 16 Scan time: 18.500 The best scores are: opt bits E(85289) XP_011511162 (OMIM: 600922,613780) PREDICTED: myos (1913) 12806 859.5 0 NP_444253 (OMIM: 600922,613780) myosin light chain (1914) 12794 858.8 0 NP_001308238 (OMIM: 600922,613780) myosin light ch (1738) 11621 781.6 0 NP_444255 (OMIM: 600922,613780) myosin light chain (1863) 11073 745.7 1e-213 XP_011511163 (OMIM: 600922,613780) PREDICTED: myos (1846) 9885 667.6 3.2e-190 NP_444254 (OMIM: 600922,613780) myosin light chain (1845) 9427 637.5 3.6e-181 NP_444256 (OMIM: 600922,613780) myosin light chain (1794) 7706 524.5 3.9e-147 XP_016861958 (OMIM: 600922,613780) PREDICTED: myos ( 991) 6578 450.0 5.7e-125 XP_016861959 (OMIM: 600922,613780) PREDICTED: myos ( 713) 4751 329.7 6.4e-89 XP_016861960 (OMIM: 600922,613780) PREDICTED: myos ( 714) 4739 328.9 1.1e-88 XP_006721397 (OMIM: 612147) PREDICTED: myosin ligh ( 478) 1056 86.7 6.1e-16 NP_001295230 (OMIM: 612147) myosin light chain kin ( 478) 1056 86.7 6.1e-16 NP_872299 (OMIM: 612147) myosin light chain kinase ( 819) 1056 87.1 8.2e-16 NP_149109 (OMIM: 192600,606566) myosin light chain ( 596) 1049 86.4 9.5e-16 NP_003310 (OMIM: 188840,600334,603689,604145,60880 (26926) 1090 91.6 1.2e-15 XP_016860312 (OMIM: 188840,600334,603689,604145,60 (26973) 1090 91.6 1.2e-15 NP_597676 (OMIM: 188840,600334,603689,604145,60880 (27051) 1090 91.6 1.2e-15 NP_597681 (OMIM: 188840,600334,603689,604145,60880 (27118) 1090 91.6 1.2e-15 XP_016860311 (OMIM: 188840,600334,603689,604145,60 (33101) 1090 91.7 1.3e-15 NP_596869 (OMIM: 188840,600334,603689,604145,60880 (33423) 1090 91.7 1.3e-15 XP_016860310 (OMIM: 188840,600334,603689,604145,60 (34087) 1090 91.7 1.4e-15 XP_016860309 (OMIM: 188840,600334,603689,604145,60 (34088) 1090 91.7 1.4e-15 NP_001243779 (OMIM: 188840,600334,603689,604145,60 (34350) 1090 91.7 1.4e-15 XP_016860308 (OMIM: 188840,600334,603689,604145,60 (35622) 1090 91.8 1.4e-15 NP_001254479 (OMIM: 188840,600334,603689,604145,60 (35991) 1090 91.8 1.4e-15 NP_444259 (OMIM: 600922,613780) myosin light chain ( 153) 1015 83.3 2.1e-15 XP_016861962 (OMIM: 600922,613780) PREDICTED: myos ( 153) 1015 83.3 2.1e-15 NP_444260 (OMIM: 600922,613780) myosin light chain ( 154) 1003 82.5 3.7e-15 XP_016861961 (OMIM: 600922,613780) PREDICTED: myos ( 154) 1003 82.5 3.7e-15 XP_005251814 (OMIM: 600831) PREDICTED: death-assoc ( 839) 912 77.6 5.9e-13 NP_001275659 (OMIM: 600831) death-associated prote (1430) 912 78.0 7.9e-13 NP_001275660 (OMIM: 600831) death-associated prote (1430) 912 78.0 7.9e-13 NP_004929 (OMIM: 600831) death-associated protein (1430) 912 78.0 7.9e-13 NP_001275658 (OMIM: 600831) death-associated prote (1430) 912 78.0 7.9e-13 XP_016877533 (OMIM: 616567) PREDICTED: death-assoc ( 350) 881 75.0 1.5e-12 NP_055141 (OMIM: 616567) death-associated protein ( 370) 881 75.1 1.5e-12 XP_011519716 (OMIM: 616567) PREDICTED: death-assoc ( 380) 881 75.1 1.6e-12 XP_011519715 (OMIM: 616567) PREDICTED: death-assoc ( 389) 881 75.1 1.6e-12 XP_011519717 (OMIM: 616567) PREDICTED: death-assoc ( 359) 857 73.5 4.5e-12 XP_011519718 (OMIM: 616567) PREDICTED: death-assoc ( 488) 857 73.7 5.3e-12 XP_005259565 (OMIM: 603289) PREDICTED: death-assoc ( 454) 845 72.8 8.8e-12 NP_001339 (OMIM: 603289) death-associated protein ( 454) 845 72.8 8.8e-12 XP_016877534 (OMIM: 616567) PREDICTED: death-assoc ( 316) 802 69.8 5.1e-11 XP_011519719 (OMIM: 616567) PREDICTED: death-assoc ( 316) 802 69.8 5.1e-11 XP_016877535 (OMIM: 616567) PREDICTED: death-assoc ( 316) 802 69.8 5.1e-11 NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370) 767 67.6 2.8e-10 XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413) 767 67.6 2.9e-10 XP_006717546 (OMIM: 607957) PREDICTED: calcium/cal ( 355) 747 66.2 6.7e-10 NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357) 747 66.2 6.7e-10 NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385) 747 66.3 7e-10 >>XP_011511162 (OMIM: 600922,613780) PREDICTED: myosin l (1913 aa) initn: 12806 init1: 12806 opt: 12806 Z-score: 4573.0 bits: 859.5 E(85289): 0 Smith-Waterman score: 12806; 99.9% identity (99.9% similar) in 1913 aa overlap (1-1913:1-1913) 10 20 30 40 50 60 pF1KB1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 LTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_011 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 DSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_011 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB1 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB1 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB1 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB1 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB1 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB1 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB1 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB1 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB1 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB1 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB1 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB1 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB1 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB1 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB1 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB1 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB1 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEDVSQAFLEAVA 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB1 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 pF1KB1 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1870 1880 1890 1900 1910 >>NP_444253 (OMIM: 600922,613780) myosin light chain kin (1914 aa) initn: 11970 init1: 11970 opt: 12794 Z-score: 4568.8 bits: 858.8 E(85289): 0 Smith-Waterman score: 12794; 99.8% identity (99.9% similar) in 1914 aa overlap (1-1913:1-1914) 10 20 30 40 50 60 pF1KB1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 LTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: NP_444 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 DSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_444 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB1 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB1 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB1 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB1 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB1 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB1 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB1 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB1 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB1 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB1 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB1 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB1 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB1 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB1 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB1 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB1 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 pF1KB1 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAV ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_444 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KB1 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KB1 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1870 1880 1890 1900 1910 >>NP_001308238 (OMIM: 600922,613780) myosin light chain (1738 aa) initn: 10797 init1: 10797 opt: 11621 Z-score: 4152.7 bits: 781.6 E(85289): 0 Smith-Waterman score: 11621; 99.9% identity (99.9% similar) in 1738 aa overlap (177-1913:1-1738) 150 160 170 180 190 200 pF1KB1 SAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR :::::::::::::::::::::::::::::: NP_001 MGRFSCKITGRPQPQVTWLKGNVPLQPSAR 10 20 30 210 220 230 240 250 260 pF1KB1 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKA 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB1 TNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCK 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB1 DSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB1 PGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVA 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB1 WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVER :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: NP_001 WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVER 280 290 300 310 320 330 510 520 530 540 550 560 pF1KB1 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA 340 350 360 370 380 390 570 580 590 600 610 620 pF1KB1 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 400 410 420 430 440 450 630 640 650 660 670 680 pF1KB1 QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF 460 470 480 490 500 510 690 700 710 720 730 740 pF1KB1 PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAG 520 530 540 550 560 570 750 760 770 780 790 800 pF1KB1 DPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ 580 590 600 610 620 630 810 820 830 840 850 860 pF1KB1 VSLMLQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSLMLQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDG 640 650 660 670 680 690 870 880 890 900 910 920 pF1KB1 EDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFR 700 710 720 730 740 750 930 940 950 960 970 980 pF1KB1 ANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLG 760 770 780 790 800 810 990 1000 1010 1020 1030 1040 pF1KB1 GKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET 820 830 840 850 860 870 1050 1060 1070 1080 1090 1100 pF1KB1 LKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQD 880 890 900 910 920 930 1110 1120 1130 1140 1150 1160 pF1KB1 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 940 950 960 970 980 990 1170 1180 1190 1200 1210 1220 pF1KB1 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1000 1010 1020 1030 1040 1050 1230 1240 1250 1260 1270 1280 pF1KB1 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1060 1070 1080 1090 1100 1110 1290 1300 1310 1320 1330 1340 pF1KB1 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1120 1130 1140 1150 1160 1170 1350 1360 1370 1380 1390 1400 pF1KB1 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRA 1180 1190 1200 1210 1220 1230 1410 1420 1430 1440 1450 1460 pF1KB1 INVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDI 1240 1250 1260 1270 1280 1290 1470 1480 1490 1500 1510 1520 pF1KB1 EERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVD 1300 1310 1320 1330 1340 1350 1530 1540 1550 1560 1570 1580 pF1KB1 AFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDL 1360 1370 1380 1390 1400 1410 1590 1600 1610 1620 1630 1640 pF1KB1 KPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWS 1420 1430 1440 1450 1460 1470 1650 1660 1670 1680 1690 1700 pF1KB1 IGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKN 1480 1490 1500 1510 1520 1530 1710 1720 1730 1740 1750 1760 pF1KB1 RLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISG 1540 1550 1560 1570 1580 1590 1770 1780 1790 1800 1810 1820 pF1KB1 LSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAA ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: NP_001 LSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAA 1600 1610 1620 1630 1640 1650 1830 1840 1850 1860 1870 1880 pF1KB1 RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVN 1660 1670 1680 1690 1700 1710 1890 1900 1910 pF1KB1 SLGEATCTAELIVETMEEGEGEGEEEEE :::::::::::::::::::::::::::: NP_001 SLGEATCTAELIVETMEEGEGEGEEEEE 1720 1730 >>NP_444255 (OMIM: 600922,613780) myosin light chain kin (1863 aa) initn: 11903 init1: 11073 opt: 11073 Z-score: 3957.9 bits: 745.7 E(85289): 1e-213 Smith-Waterman score: 12345; 97.2% identity (97.2% similar) in 1914 aa overlap (1-1913:1-1863) 10 20 30 40 50 60 pF1KB1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 LTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: NP_444 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 DSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_444 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB1 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB1 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB1 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB1 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB1 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB1 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB1 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB1 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB1 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB1 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB1 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB1 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB1 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB1 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB1 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF :::::::::::::::::::::::::::::::::: NP_444 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL-------------------------- 1630 1640 1650 1690 1700 1710 1720 1730 1740 pF1KB1 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM ::::::::::::::::::::::::::::::::::: NP_444 -------------------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1660 1670 1680 1750 1760 1770 1780 1790 pF1KB1 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAV ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_444 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1690 1700 1710 1720 1730 1740 1800 1810 1820 1830 1840 1850 pF1KB1 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1750 1760 1770 1780 1790 1800 1860 1870 1880 1890 1900 1910 pF1KB1 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1810 1820 1830 1840 1850 1860 >>XP_011511163 (OMIM: 600922,613780) PREDICTED: myosin l (1846 aa) initn: 10707 init1: 9877 opt: 9885 Z-score: 3536.1 bits: 667.6 E(85289): 3.2e-190 Smith-Waterman score: 12198; 96.3% identity (96.3% similar) in 1914 aa overlap (1-1913:1-1846) 10 20 30 40 50 60 pF1KB1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 LTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_011 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 DSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_011 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB1 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB1 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB1 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB1 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB1 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB1 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB1 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB1 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB1 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB1 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB1 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB1 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA :::::::::::::::::::::::::::::::: XP_011 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGS---------------------------- 1450 1460 1470 1510 1520 1530 1540 1550 1560 pF1KB1 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER :::::::::::::::::::: XP_011 ----------------------------------------VSGGELFERIIDEDFELTER 1480 1490 1570 1580 1590 1600 1610 1620 pF1KB1 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1500 1510 1520 1530 1540 1550 1630 1640 1650 1660 1670 1680 pF1KB1 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1560 1570 1580 1590 1600 1610 1690 1700 1710 1720 1730 1740 pF1KB1 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1620 1630 1640 1650 1660 1670 1750 1760 1770 1780 1790 pF1KB1 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAV ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_011 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1680 1690 1700 1710 1720 1730 1800 1810 1820 1830 1840 1850 pF1KB1 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1740 1750 1760 1770 1780 1790 1860 1870 1880 1890 1900 1910 pF1KB1 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1800 1810 1820 1830 1840 >>NP_444254 (OMIM: 600922,613780) myosin light chain kin (1845 aa) initn: 8594 init1: 8594 opt: 9427 Z-score: 3373.5 bits: 637.5 E(85289): 3.6e-181 Smith-Waterman score: 12170; 96.3% identity (96.3% similar) in 1914 aa overlap (1-1913:1-1845) 10 20 30 40 50 60 pF1KB1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 LTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: NP_444 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR :::::::::::::::: : NP_444 QSQEVKENQTVKFRCE--G----------------------------------------- 430 490 500 510 520 530 540 pF1KB1 DSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT :::::::::::::::::::::::::::::::::: NP_444 --------------------------LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 440 450 460 470 550 560 570 580 590 600 pF1KB1 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 480 490 500 510 520 530 610 620 630 640 650 660 pF1KB1 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 540 550 560 570 580 590 670 680 690 700 710 720 pF1KB1 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 600 610 620 630 640 650 730 740 750 760 770 780 pF1KB1 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 660 670 680 690 700 710 790 800 810 820 830 840 pF1KB1 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 720 730 740 750 760 770 850 860 870 880 890 900 pF1KB1 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 780 790 800 810 820 830 910 920 930 940 950 960 pF1KB1 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 840 850 860 870 880 890 970 980 990 1000 1010 1020 pF1KB1 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 900 910 920 930 940 950 1030 1040 1050 1060 1070 1080 pF1KB1 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 960 970 980 990 1000 1010 1090 1100 1110 1120 1130 1140 pF1KB1 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1020 1030 1040 1050 1060 1070 1150 1160 1170 1180 1190 1200 pF1KB1 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1080 1090 1100 1110 1120 1130 1210 1220 1230 1240 1250 1260 pF1KB1 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1140 1150 1160 1170 1180 1190 1270 1280 1290 1300 1310 1320 pF1KB1 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1200 1210 1220 1230 1240 1250 1330 1340 1350 1360 1370 1380 pF1KB1 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1260 1270 1280 1290 1300 1310 1390 1400 1410 1420 1430 1440 pF1KB1 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1320 1330 1340 1350 1360 1370 1450 1460 1470 1480 1490 1500 pF1KB1 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1380 1390 1400 1410 1420 1430 1510 1520 1530 1540 1550 1560 pF1KB1 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1440 1450 1460 1470 1480 1490 1570 1580 1590 1600 1610 1620 pF1KB1 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1500 1510 1520 1530 1540 1550 1630 1640 1650 1660 1670 1680 pF1KB1 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1560 1570 1580 1590 1600 1610 1690 1700 1710 1720 1730 1740 pF1KB1 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1620 1630 1640 1650 1660 1670 1750 1760 1770 1780 1790 pF1KB1 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAV ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_444 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1680 1690 1700 1710 1720 1730 1800 1810 1820 1830 1840 1850 pF1KB1 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1740 1750 1760 1770 1780 1790 1860 1870 1880 1890 1900 1910 pF1KB1 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1800 1810 1820 1830 1840 >>NP_444256 (OMIM: 600922,613780) myosin light chain kin (1794 aa) initn: 8527 init1: 7697 opt: 7706 Z-score: 2762.6 bits: 524.5 E(85289): 3.9e-147 Smith-Waterman score: 11721; 93.6% identity (93.6% similar) in 1914 aa overlap (1-1913:1-1794) 10 20 30 40 50 60 pF1KB1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 LTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: NP_444 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR :::::::::::::::: : NP_444 QSQEVKENQTVKFRCE--G----------------------------------------- 430 490 500 510 520 530 540 pF1KB1 DSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT :::::::::::::::::::::::::::::::::: NP_444 --------------------------LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 440 450 460 470 550 560 570 580 590 600 pF1KB1 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 480 490 500 510 520 530 610 620 630 640 650 660 pF1KB1 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 540 550 560 570 580 590 670 680 690 700 710 720 pF1KB1 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 600 610 620 630 640 650 730 740 750 760 770 780 pF1KB1 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 660 670 680 690 700 710 790 800 810 820 830 840 pF1KB1 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 720 730 740 750 760 770 850 860 870 880 890 900 pF1KB1 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 780 790 800 810 820 830 910 920 930 940 950 960 pF1KB1 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 840 850 860 870 880 890 970 980 990 1000 1010 1020 pF1KB1 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 900 910 920 930 940 950 1030 1040 1050 1060 1070 1080 pF1KB1 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 960 970 980 990 1000 1010 1090 1100 1110 1120 1130 1140 pF1KB1 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1020 1030 1040 1050 1060 1070 1150 1160 1170 1180 1190 1200 pF1KB1 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1080 1090 1100 1110 1120 1130 1210 1220 1230 1240 1250 1260 pF1KB1 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1140 1150 1160 1170 1180 1190 1270 1280 1290 1300 1310 1320 pF1KB1 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1200 1210 1220 1230 1240 1250 1330 1340 1350 1360 1370 1380 pF1KB1 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1260 1270 1280 1290 1300 1310 1390 1400 1410 1420 1430 1440 pF1KB1 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1320 1330 1340 1350 1360 1370 1450 1460 1470 1480 1490 1500 pF1KB1 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1380 1390 1400 1410 1420 1430 1510 1520 1530 1540 1550 1560 pF1KB1 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1440 1450 1460 1470 1480 1490 1570 1580 1590 1600 1610 1620 pF1KB1 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1500 1510 1520 1530 1540 1550 1630 1640 1650 1660 1670 1680 pF1KB1 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF :::::::::::::::::::::::::::::::::: NP_444 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL-------------------------- 1560 1570 1580 1690 1700 1710 1720 1730 1740 pF1KB1 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM ::::::::::::::::::::::::::::::::::: NP_444 -------------------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1590 1600 1610 1620 1750 1760 1770 1780 1790 pF1KB1 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAV ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_444 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1630 1640 1650 1660 1670 1680 1800 1810 1820 1830 1840 1850 pF1KB1 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1690 1700 1710 1720 1730 1740 1860 1870 1880 1890 1900 1910 pF1KB1 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1750 1760 1770 1780 1790 >>XP_016861958 (OMIM: 600922,613780) PREDICTED: myosin l (991 aa) initn: 6578 init1: 6578 opt: 6578 Z-score: 2364.6 bits: 450.0 E(85289): 5.7e-125 Smith-Waterman score: 6578; 100.0% identity (100.0% similar) in 991 aa overlap (923-1913:1-991) 900 910 920 930 940 950 pF1KB1 EQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVD :::::::::::::::::::::::::::::: XP_016 MDFRANLQRQVKPKTVSEEERKVHSPQQVD 10 20 30 960 970 980 990 1000 1010 pF1KB1 FRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSK 40 50 60 70 80 90 1020 1030 1040 1050 1060 1070 pF1KB1 PLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVK 100 110 120 130 140 150 1080 1090 1100 1110 1120 1130 pF1KB1 NDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWT 160 170 180 190 200 210 1140 1150 1160 1170 1180 1190 pF1KB1 LNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 220 230 240 250 260 270 1200 1210 1220 1230 1240 1250 pF1KB1 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 280 290 300 310 320 330 1260 1270 1280 1290 1300 1310 pF1KB1 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 340 350 360 370 380 390 1320 1330 1340 1350 1360 1370 pF1KB1 ENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD 400 410 420 430 440 450 1380 1390 1400 1410 1420 1430 pF1KB1 SANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 460 470 480 490 500 510 1440 1450 1460 1470 1480 1490 pF1KB1 DEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAG 520 530 540 550 560 570 1500 1510 1520 1530 1540 1550 pF1KB1 KFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIID 580 590 600 610 620 630 1560 1570 1580 1590 1600 1610 pF1KB1 EDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRL 640 650 660 670 680 690 1620 1630 1640 1650 1660 1670 pF1KB1 ENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLAN 700 710 720 730 740 750 1680 1690 1700 1710 1720 1730 pF1KB1 VTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLS 760 770 780 790 800 810 1740 1750 1760 1770 1780 1790 pF1KB1 KDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEDVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEDVS 820 830 840 850 860 870 1800 1810 1820 1830 1840 1850 pF1KB1 QAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 880 890 900 910 920 930 1860 1870 1880 1890 1900 1910 pF1KB1 HFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 940 950 960 970 980 990 pF1KB1 E : XP_016 E >>XP_016861959 (OMIM: 600922,613780) PREDICTED: myosin l (713 aa) initn: 4751 init1: 4751 opt: 4751 Z-score: 1717.4 bits: 329.7 E(85289): 6.4e-89 Smith-Waterman score: 4751; 100.0% identity (100.0% similar) in 713 aa overlap (1201-1913:1-713) 1180 1190 1200 1210 1220 1230 pF1KB1 VAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKT :::::::::::::::::::::::::::::: XP_016 MKSRRPKSSLPPVLGTESDATVKKKPAPKT 10 20 30 1240 1250 1260 1270 1280 1290 pF1KB1 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 40 50 60 70 80 90 1300 1310 1320 1330 1340 1350 pF1KB1 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 100 110 120 130 140 150 1360 1370 1380 1390 1400 1410 pF1KB1 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVY 160 170 180 190 200 210 1420 1430 1440 1450 1460 1470 pF1KB1 GTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERL 220 230 240 250 260 270 1480 1490 1500 1510 1520 1530 pF1KB1 GSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEE 280 290 300 310 320 330 1540 1550 1560 1570 1580 1590 pF1KB1 KANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPEN 340 350 360 370 380 390 1600 1610 1620 1630 1640 1650 pF1KB1 IMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVI 400 410 420 430 440 450 1660 1670 1680 1690 1700 1710 pF1KB1 CYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDC 460 470 480 490 500 510 1720 1730 1740 1750 1760 1770 pF1KB1 TQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGR 520 530 540 550 560 570 1780 1790 1800 1810 1820 1830 pF1KB1 KSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSTGSPTSPLNAEKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 580 590 600 610 620 630 1840 1850 1860 1870 1880 1890 pF1KB1 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 640 650 660 670 680 690 1900 1910 pF1KB1 TCTAELIVETMEEGEGEGEEEEE ::::::::::::::::::::::: XP_016 TCTAELIVETMEEGEGEGEEEEE 700 710 >>XP_016861960 (OMIM: 600922,613780) PREDICTED: myosin l (714 aa) initn: 3950 init1: 3915 opt: 4739 Z-score: 1713.1 bits: 328.9 E(85289): 1.1e-88 Smith-Waterman score: 4739; 99.9% identity (99.9% similar) in 714 aa overlap (1201-1913:1-714) 1180 1190 1200 1210 1220 1230 pF1KB1 VAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKT :::::::::::::::::::::::::::::: XP_016 MKSRRPKSSLPPVLGTESDATVKKKPAPKT 10 20 30 1240 1250 1260 1270 1280 1290 pF1KB1 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 40 50 60 70 80 90 1300 1310 1320 1330 1340 1350 pF1KB1 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 100 110 120 130 140 150 1360 1370 1380 1390 1400 1410 pF1KB1 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVY 160 170 180 190 200 210 1420 1430 1440 1450 1460 1470 pF1KB1 GTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERL 220 230 240 250 260 270 1480 1490 1500 1510 1520 1530 pF1KB1 GSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEE 280 290 300 310 320 330 1540 1550 1560 1570 1580 1590 pF1KB1 KANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPEN 340 350 360 370 380 390 1600 1610 1620 1630 1640 1650 pF1KB1 IMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVI 400 410 420 430 440 450 1660 1670 1680 1690 1700 1710 pF1KB1 CYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDC 460 470 480 490 500 510 1720 1730 1740 1750 1760 1770 pF1KB1 TQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGR 520 530 540 550 560 570 1780 1790 1800 1810 1820 pF1KB1 KSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: XP_016 KSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 580 590 600 610 620 630 1830 1840 1850 1860 1870 1880 pF1KB1 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 640 650 660 670 680 690 1890 1900 1910 pF1KB1 ATCTAELIVETMEEGEGEGEEEEE :::::::::::::::::::::::: XP_016 ATCTAELIVETMEEGEGEGEEEEE 700 710 1913 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:55:16 2016 done: Thu Nov 3 11:55:19 2016 Total Scan time: 18.500 Total Display time: 1.430 Function used was FASTA [36.3.4 Apr, 2011]