Result of FASTA (omim) for pF1KB1891
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB1891, 1463 aa
  1>>>pF1KB1891 1463 - 1463 aa - 1463 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.6011+/-0.000503; mu= -1.2494+/- 0.032
 mean_var=483.5668+/-98.574, 0's: 0 Z-trim(121.4): 203  B-trim: 609 in 1/59
 Lambda= 0.058324
 statistics sampled from 37751 (37958) to 37751 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.445), width:  16
 Scan time: 17.620

The best scores are:                                      opt bits E(85289)
NP_004710 (OMIM: 603668) protein SCAF11 [Homo sapi (1463) 9770 838.1       0
XP_005269287 (OMIM: 603668) PREDICTED: protein SCA (1463) 9770 838.1       0
XP_011537287 (OMIM: 603668) PREDICTED: protein SCA (1463) 9770 838.1       0
XP_011537286 (OMIM: 603668) PREDICTED: protein SCA (1479) 9770 838.1       0
XP_016875710 (OMIM: 603668) PREDICTED: protein SCA (1428) 9258 795.0       0
XP_016875708 (OMIM: 603668) PREDICTED: protein SCA (1473) 9258 795.0       0
XP_016875706 (OMIM: 603668) PREDICTED: protein SCA (1473) 9258 795.0       0
XP_016875712 (OMIM: 603668) PREDICTED: protein SCA (1411) 9251 794.4       0
XP_016875711 (OMIM: 603668) PREDICTED: protein SCA (1418) 9251 794.4       0
XP_016875707 (OMIM: 603668) PREDICTED: protein SCA (1436) 8957 769.7       0
XP_016875709 (OMIM: 603668) PREDICTED: protein SCA (1400) 8278 712.5 5.6e-204
XP_011518539 (OMIM: 611780) PREDICTED: PHD and RIN (1609)  524 60.2 1.6e-07
NP_001273512 (OMIM: 611780) PHD and RING finger do (1645)  524 60.2 1.6e-07
XP_005253084 (OMIM: 611780) PREDICTED: PHD and RIN (1646)  524 60.2 1.6e-07
NP_001273511 (OMIM: 611780) PHD and RING finger do (1647)  524 60.2 1.6e-07
XP_011518538 (OMIM: 611780) PREDICTED: PHD and RIN (1647)  524 60.2 1.6e-07
XP_005253082 (OMIM: 611780) PREDICTED: PHD and RIN (1648)  524 60.2 1.6e-07
NP_065952 (OMIM: 611780) PHD and RING finger domai (1648)  524 60.2 1.6e-07
NP_001273510 (OMIM: 611780) PHD and RING finger do (1649)  524 60.2 1.6e-07
XP_005266369 (OMIM: 616453) PREDICTED: zinc finger (1564)  339 44.6  0.0074
NP_055885 (OMIM: 616453) zinc finger CCCH domain-c (1564)  339 44.6  0.0074
NP_001317495 (OMIM: 616453) zinc finger CCCH domai (1668)  339 44.6  0.0078
NP_001317494 (OMIM: 616453) zinc finger CCCH domai (1668)  339 44.6  0.0078
NP_001317496 (OMIM: 616453) zinc finger CCCH domai (1668)  339 44.6  0.0078
XP_005266367 (OMIM: 616453) PREDICTED: zinc finger (1669)  339 44.6  0.0078
XP_016875968 (OMIM: 616453) PREDICTED: zinc finger (1669)  339 44.6  0.0078
XP_016875969 (OMIM: 616453) PREDICTED: zinc finger (1669)  339 44.6  0.0078
NP_001317493 (OMIM: 616453) zinc finger CCCH domai (1669)  339 44.6  0.0078
XP_016875966 (OMIM: 616453) PREDICTED: zinc finger (1669)  339 44.6  0.0078
NP_001070256 (OMIM: 616453) zinc finger CCCH domai (1669)  339 44.6  0.0078
XP_016875967 (OMIM: 616453) PREDICTED: zinc finger (1669)  339 44.6  0.0078


>>NP_004710 (OMIM: 603668) protein SCAF11 [Homo sapiens]  (1463 aa)
 initn: 9770 init1: 9770 opt: 9770  Z-score: 4461.3  bits: 838.1 E(85289):    0
Smith-Waterman score: 9770; 99.9% identity (99.9% similar) in 1463 aa overlap (1-1463:1-1463)

               10        20        30        40        50        60
pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDYNNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_004 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB1 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB1 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB1 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB1 RGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRENKRSQPRVKD
       ::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
NP_004 RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB1 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB1 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB1 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB1 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB1 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB1 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB1 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB1 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB1 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY
             1390      1400      1410      1420      1430      1440

             1450      1460   
pF1KB1 KYSRKGSQKKTLEEPVSTEKNIG
       :::::::::::::::::::::::
NP_004 KYSRKGSQKKTLEEPVSTEKNIG
             1450      1460   

>>XP_005269287 (OMIM: 603668) PREDICTED: protein SCAF11   (1463 aa)
 initn: 9770 init1: 9770 opt: 9770  Z-score: 4461.3  bits: 838.1 E(85289):    0
Smith-Waterman score: 9770; 99.9% identity (99.9% similar) in 1463 aa overlap (1-1463:1-1463)

               10        20        30        40        50        60
pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDYNNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
XP_005 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB1 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB1 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB1 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB1 RGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRENKRSQPRVKD
       ::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
XP_005 RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB1 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB1 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB1 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB1 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB1 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB1 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB1 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB1 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB1 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY
             1390      1400      1410      1420      1430      1440

             1450      1460   
pF1KB1 KYSRKGSQKKTLEEPVSTEKNIG
       :::::::::::::::::::::::
XP_005 KYSRKGSQKKTLEEPVSTEKNIG
             1450      1460   

>>XP_011537287 (OMIM: 603668) PREDICTED: protein SCAF11   (1463 aa)
 initn: 9770 init1: 9770 opt: 9770  Z-score: 4461.3  bits: 838.1 E(85289):    0
Smith-Waterman score: 9770; 99.9% identity (99.9% similar) in 1463 aa overlap (1-1463:1-1463)

               10        20        30        40        50        60
pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB1 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB1 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB1 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB1 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB1 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB1 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB1 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB1 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB1 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB1 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDYNNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
XP_011 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB1 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB1 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB1 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB1 RGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRENKRSQPRVKD
       ::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
XP_011 RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB1 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB1 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB1 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB1 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB1 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB1 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB1 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB1 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB1 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY
             1390      1400      1410      1420      1430      1440

             1450      1460   
pF1KB1 KYSRKGSQKKTLEEPVSTEKNIG
       :::::::::::::::::::::::
XP_011 KYSRKGSQKKTLEEPVSTEKNIG
             1450      1460   

>>XP_011537286 (OMIM: 603668) PREDICTED: protein SCAF11   (1479 aa)
 initn: 9770 init1: 9770 opt: 9770  Z-score: 4461.3  bits: 838.1 E(85289):    0
Smith-Waterman score: 9770; 99.9% identity (99.9% similar) in 1463 aa overlap (1-1463:17-1479)

                               10        20        30        40    
pF1KB1                 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPIC
                       ::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIVSIFSNKETLFQREMKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPIC
               10        20        30        40        50        60

           50        60        70        80        90       100    
pF1KB1 LNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKK
               70        80        90       100       110       120

          110       120       130       140       150       160    
pF1KB1 QLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGG
              130       140       150       160       170       180

          170       180       190       200       210       220    
pF1KB1 KKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALI
              190       200       210       220       230       240

          230       240       250       260       270       280    
pF1KB1 RQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSC
              250       260       270       280       290       300

          290       300       310       320       330       340    
pF1KB1 KGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNS
              310       320       330       340       350       360

          350       360       370       380       390       400    
pF1KB1 GCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSND
              370       380       390       400       410       420

          410       420       430       440       450       460    
pF1KB1 SVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANY
              430       440       450       460       470       480

          470       480       490       500       510       520    
pF1KB1 DTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLE
              490       500       510       520       530       540

          530       540       550       560       570       580    
pF1KB1 KQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKI
              550       560       570       580       590       600

          590       600       610       620       630       640    
pF1KB1 TESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVE
              610       620       630       640       650       660

          650       660       670       680       690       700    
pF1KB1 IIATCDTFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQ
       ::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQ
              670       680       690       700       710       720

          710       720       730       740       750       760    
pF1KB1 IQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLAD
              730       740       750       760       770       780

          770       780       790       800       810       820    
pF1KB1 EKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETG
              790       800       810       820       830       840

          830       840       850       860       870       880    
pF1KB1 KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPR
       ::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_011 KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPR
              850       860       870       880       890       900

          890       900       910       920       930       940    
pF1KB1 RETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSR
              910       920       930       940       950       960

          950       960       970       980       990      1000    
pF1KB1 CRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIH
              970       980       990      1000      1010      1020

         1010      1020      1030      1040      1050      1060    
pF1KB1 LDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFG
             1030      1040      1050      1060      1070      1080

         1070      1080      1090      1100      1110      1120    
pF1KB1 SGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYK
             1090      1100      1110      1120      1130      1140

         1130      1140      1150      1160      1170      1180    
pF1KB1 RKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETS
             1150      1160      1170      1180      1190      1200

         1190      1200      1210      1220      1230      1240    
pF1KB1 GQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQR
             1210      1220      1230      1240      1250      1260

         1250      1260      1270      1280      1290      1300    
pF1KB1 NPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGI
             1270      1280      1290      1300      1310      1320

         1310      1320      1330      1340      1350      1360    
pF1KB1 PSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAV
             1330      1340      1350      1360      1370      1380

         1370      1380      1390      1400      1410      1420    
pF1KB1 EASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEV
             1390      1400      1410      1420      1430      1440

         1430      1440      1450      1460   
pF1KB1 NSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
       :::::::::::::::::::::::::::::::::::::::
XP_011 NSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
             1450      1460      1470         

>>XP_016875710 (OMIM: 603668) PREDICTED: protein SCAF11   (1428 aa)
 initn: 9255 init1: 9255 opt: 9258  Z-score: 4228.6  bits: 795.0 E(85289):    0
Smith-Waterman score: 9258; 99.6% identity (99.8% similar) in 1395 aa overlap (69-1463:34-1428)

       40        50        60        70        80        90        
pF1KB1 DRCPICLNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYV
                                     .:  ::::::::::::::::::::::::::
XP_016 HPFFQLQVHLSHNLYPDVHVPGFSRELFIPIKTLETLASCPIDRKPFQAVFKFSALEGYV
            10        20        30        40        50        60   

      100       110       120       130       140       150        
pF1KB1 KVQVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVQVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSL
            70        80        90       100       110       120   

      160       170       180       190       200       210        
pF1KB1 YSETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEAS
           130       140       150       160       170       180   

      220       230       240       250       260       270        
pF1KB1 EISALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EISALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFE
           190       200       210       220       230       240   

      280       290       300       310       320       330        
pF1KB1 HFGTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFGTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRS
           250       260       270       280       290       300   

      340       350       360       370       380       390        
pF1KB1 PISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPE
           310       320       330       340       350       360   

      400       410       420       430       440       450        
pF1KB1 KSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESE
           370       380       390       400       410       420   

      460       470       480       490       500       510        
pF1KB1 KHTANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHTANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEK
           430       440       450       460       470       480   

      520       530       540       550       560       570        
pF1KB1 GGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESV
           490       500       510       520       530       540   

      580       590       600       610       620       630        
pF1KB1 VNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHV
           550       560       570       580       590       600   

      640       650       660       670       680       690        
pF1KB1 ETEDVEIIATCDTFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELP
       ::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_016 ETEDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELP
           610       620       630       640       650       660   

      700       710       720       730       740       750        
pF1KB1 KTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMP
           670       680       690       700       710       720   

      760       770       780       790       800       810        
pF1KB1 SSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPS
           730       740       750       760       770       780   

      820       830       840       850       860       870        
pF1KB1 PRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 PRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRS
           790       800       810       820       830       840   

      880       890       900       910       920       930        
pF1KB1 ESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSH
           850       860       870       880       890       900   

      940       950       960       970       980       990        
pF1KB1 SRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRK
           910       920       930       940       950       960   

     1000      1010      1020      1030      1040      1050        
pF1KB1 EKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNS
           970       980       990      1000      1010      1020   

     1060      1070      1080      1090      1100      1110        
pF1KB1 WNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFV
          1030      1040      1050      1060      1070      1080   

     1120      1130      1140      1150      1160      1170        
pF1KB1 EQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMK
          1090      1100      1110      1120      1130      1140   

     1180      1190      1200      1210      1220      1230        
pF1KB1 QEEETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEEETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAP
          1150      1160      1170      1180      1190      1200   

     1240      1250      1260      1270      1280      1290        
pF1KB1 LMNIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMNIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDG
          1210      1220      1230      1240      1250      1260   

     1300      1310      1320      1330      1340      1350        
pF1KB1 KQLQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQLQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAES
          1270      1280      1290      1300      1310      1320   

     1360      1370      1380      1390      1400      1410        
pF1KB1 KVSVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVSVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCH
          1330      1340      1350      1360      1370      1380   

     1420      1430      1440      1450      1460   
pF1KB1 SKSGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKSGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
          1390      1400      1410      1420        

>>XP_016875708 (OMIM: 603668) PREDICTED: protein SCAF11   (1473 aa)
 initn: 9255 init1: 9255 opt: 9258  Z-score: 4228.5  bits: 795.0 E(85289):    0
Smith-Waterman score: 9740; 99.2% identity (99.3% similar) in 1473 aa overlap (1-1463:1-1473)

               10        20        30        40        50        60
pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
               10        20        30        40        50        60

               70                  80        90       100       110
pF1KB1 HVFCMTCILKWAE----------TLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK
       :::::::::::::          :::::::::::::::::::::::::::::::::::::
XP_016 HVFCMTCILKWAEELFIPIKTLETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK
               70        80        90       100       110       120

              120       130       140       150       160       170
pF1KB1 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI
              130       140       150       160       170       180

              180       190       200       210       220       230
pF1KB1 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE
              190       200       210       220       230       240

              240       250       260       270       280       290
pF1KB1 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA
              250       260       270       280       290       300

              300       310       320       330       340       350
pF1KB1 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG
              310       320       330       340       350       360

              360       370       380       390       400       410
pF1KB1 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET
              370       380       390       400       410       420

              420       430       440       450       460       470
pF1KB1 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV
              430       440       450       460       470       480

              480       490       500       510       520       530
pF1KB1 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS
              490       500       510       520       530       540

              540       550       560       570       580       590
pF1KB1 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV
              550       560       570       580       590       600

              600       610       620       630       640       650
pF1KB1 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD
              610       620       630       640       650       660

              660       670       680       690       700       710
pF1KB1 TFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS
       ::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS
              670       680       690       700       710       720

              720       730       740       750       760       770
pF1KB1 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV
              730       740       750       760       770       780

              780       790       800       810       820       830
pF1KB1 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS
              790       800       810       820       830       840

              840       850       860       870       880       890
pF1KB1 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRE
       ::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_016 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRE
              850       860       870       880       890       900

              900       910       920       930       940       950
pF1KB1 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK
              910       920       930       940       950       960

              960       970       980       990      1000      1010
pF1KB1 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP
              970       980       990      1000      1010      1020

             1020      1030      1040      1050      1060      1070
pF1KB1 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN
             1030      1040      1050      1060      1070      1080

             1080      1090      1100      1110      1120      1130
pF1KB1 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE
             1090      1100      1110      1120      1130      1140

             1140      1150      1160      1170      1180      1190
pF1KB1 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL
             1150      1160      1170      1180      1190      1200

             1200      1210      1220      1230      1240      1250
pF1KB1 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH
             1210      1220      1230      1240      1250      1260

             1260      1270      1280      1290      1300      1310
pF1KB1 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV
             1270      1280      1290      1300      1310      1320

             1320      1330      1340      1350      1360      1370
pF1KB1 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS
             1330      1340      1350      1360      1370      1380

             1380      1390      1400      1410      1420      1430
pF1KB1 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVA
             1390      1400      1410      1420      1430      1440

             1440      1450      1460   
pF1KB1 NLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
       :::::::::::::::::::::::::::::::::
XP_016 NLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
             1450      1460      1470   

>>XP_016875706 (OMIM: 603668) PREDICTED: protein SCAF11   (1473 aa)
 initn: 9255 init1: 9255 opt: 9258  Z-score: 4228.5  bits: 795.0 E(85289):    0
Smith-Waterman score: 9740; 99.2% identity (99.3% similar) in 1473 aa overlap (1-1463:1-1473)

               10        20        30        40        50        60
pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
               10        20        30        40        50        60

               70                  80        90       100       110
pF1KB1 HVFCMTCILKWAE----------TLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK
       :::::::::::::          :::::::::::::::::::::::::::::::::::::
XP_016 HVFCMTCILKWAEELFIPIKTLETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK
               70        80        90       100       110       120

              120       130       140       150       160       170
pF1KB1 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI
              130       140       150       160       170       180

              180       190       200       210       220       230
pF1KB1 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE
              190       200       210       220       230       240

              240       250       260       270       280       290
pF1KB1 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA
              250       260       270       280       290       300

              300       310       320       330       340       350
pF1KB1 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG
              310       320       330       340       350       360

              360       370       380       390       400       410
pF1KB1 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET
              370       380       390       400       410       420

              420       430       440       450       460       470
pF1KB1 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV
              430       440       450       460       470       480

              480       490       500       510       520       530
pF1KB1 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS
              490       500       510       520       530       540

              540       550       560       570       580       590
pF1KB1 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV
              550       560       570       580       590       600

              600       610       620       630       640       650
pF1KB1 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD
              610       620       630       640       650       660

              660       670       680       690       700       710
pF1KB1 TFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS
       ::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS
              670       680       690       700       710       720

              720       730       740       750       760       770
pF1KB1 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV
              730       740       750       760       770       780

              780       790       800       810       820       830
pF1KB1 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS
              790       800       810       820       830       840

              840       850       860       870       880       890
pF1KB1 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRE
       ::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_016 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRE
              850       860       870       880       890       900

              900       910       920       930       940       950
pF1KB1 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK
              910       920       930       940       950       960

              960       970       980       990      1000      1010
pF1KB1 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP
              970       980       990      1000      1010      1020

             1020      1030      1040      1050      1060      1070
pF1KB1 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN
             1030      1040      1050      1060      1070      1080

             1080      1090      1100      1110      1120      1130
pF1KB1 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE
             1090      1100      1110      1120      1130      1140

             1140      1150      1160      1170      1180      1190
pF1KB1 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL
             1150      1160      1170      1180      1190      1200

             1200      1210      1220      1230      1240      1250
pF1KB1 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH
             1210      1220      1230      1240      1250      1260

             1260      1270      1280      1290      1300      1310
pF1KB1 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV
             1270      1280      1290      1300      1310      1320

             1320      1330      1340      1350      1360      1370
pF1KB1 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS
             1330      1340      1350      1360      1370      1380

             1380      1390      1400      1410      1420      1430
pF1KB1 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVA
             1390      1400      1410      1420      1430      1440

             1440      1450      1460   
pF1KB1 NLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
       :::::::::::::::::::::::::::::::::
XP_016 NLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
             1450      1460      1470   

>>XP_016875712 (OMIM: 603668) PREDICTED: protein SCAF11   (1411 aa)
 initn: 9251 init1: 9251 opt: 9251  Z-score: 4225.5  bits: 794.4 E(85289):    0
Smith-Waterman score: 9251; 99.6% identity (99.9% similar) in 1393 aa overlap (71-1463:19-1411)

               50        60        70        80        90       100
pF1KB1 CPICLNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKV
                                     ...:::::::::::::::::::::::::::
XP_016             MGRVHLSHNLYPDVHVPGFSRTLASCPIDRKPFQAVFKFSALEGYVKV
                           10        20        30        40        

              110       120       130       140       150       160
pF1KB1 QVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYS
       50        60        70        80        90       100        

              170       180       190       200       210       220
pF1KB1 ETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEI
      110       120       130       140       150       160        

              230       240       250       260       270       280
pF1KB1 SALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHF
      170       180       190       200       210       220        

              290       300       310       320       330       340
pF1KB1 GTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPI
      230       240       250       260       270       280        

              350       360       370       380       390       400
pF1KB1 SDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKS
      290       300       310       320       330       340        

              410       420       430       440       450       460
pF1KB1 SSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKH
      350       360       370       380       390       400        

              470       480       490       500       510       520
pF1KB1 TANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGG
      410       420       430       440       450       460        

              530       540       550       560       570       580
pF1KB1 DPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVN
      470       480       490       500       510       520        

              590       600       610       620       630       640
pF1KB1 EEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVET
      530       540       550       560       570       580        

              650       660       670       680       690       700
pF1KB1 EDVEIIATCDTFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKT
       ::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_016 EDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKT
      590       600       610       620       630       640        

              710       720       730       740       750       760
pF1KB1 HIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSS
      650       660       670       680       690       700        

              770       780       790       800       810       820
pF1KB1 DLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPR
      710       720       730       740       750       760        

              830       840       850       860       870       880
pF1KB1 RETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSES
       ::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 RETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSES
      770       780       790       800       810       820        

              890       900       910       920       930       940
pF1KB1 LSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSR
      830       840       850       860       870       880        

              950       960       970       980       990      1000
pF1KB1 SPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEK
      890       900       910       920       930       940        

             1010      1020      1030      1040      1050      1060
pF1KB1 NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWN
      950       960       970       980       990      1000        

             1070      1080      1090      1100      1110      1120
pF1KB1 KNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQ
     1010      1020      1030      1040      1050      1060        

             1130      1140      1150      1160      1170      1180
pF1KB1 QSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQE
     1070      1080      1090      1100      1110      1120        

             1190      1200      1210      1220      1230      1240
pF1KB1 EETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLM
     1130      1140      1150      1160      1170      1180        

             1250      1260      1270      1280      1290      1300
pF1KB1 NIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQ
     1190      1200      1210      1220      1230      1240        

             1310      1320      1330      1340      1350      1360
pF1KB1 LQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKV
     1250      1260      1270      1280      1290      1300        

             1370      1380      1390      1400      1410      1420
pF1KB1 SVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSK
     1310      1320      1330      1340      1350      1360        

             1430      1440      1450      1460   
pF1KB1 SGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
       :::::::::::::::::::::::::::::::::::::::::::
XP_016 SGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
     1370      1380      1390      1400      1410 

>>XP_016875711 (OMIM: 603668) PREDICTED: protein SCAF11   (1418 aa)
 initn: 9251 init1: 9251 opt: 9251  Z-score: 4225.5  bits: 794.4 E(85289):    0
Smith-Waterman score: 9251; 99.6% identity (99.9% similar) in 1393 aa overlap (71-1463:26-1418)

               50        60        70        80        90       100
pF1KB1 CPICLNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKV
                                     ...:::::::::::::::::::::::::::
XP_016      MVLHPFFQLQVHLSHNLYPDVHVPGFSRTLASCPIDRKPFQAVFKFSALEGYVKV
                    10        20        30        40        50     

              110       120       130       140       150       160
pF1KB1 QVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYS
          60        70        80        90       100       110     

              170       180       190       200       210       220
pF1KB1 ETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEI
         120       130       140       150       160       170     

              230       240       250       260       270       280
pF1KB1 SALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHF
         180       190       200       210       220       230     

              290       300       310       320       330       340
pF1KB1 GTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPI
         240       250       260       270       280       290     

              350       360       370       380       390       400
pF1KB1 SDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKS
         300       310       320       330       340       350     

              410       420       430       440       450       460
pF1KB1 SSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKH
         360       370       380       390       400       410     

              470       480       490       500       510       520
pF1KB1 TANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGG
         420       430       440       450       460       470     

              530       540       550       560       570       580
pF1KB1 DPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVN
         480       490       500       510       520       530     

              590       600       610       620       630       640
pF1KB1 EEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVET
         540       550       560       570       580       590     

              650       660       670       680       690       700
pF1KB1 EDVEIIATCDTFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKT
       ::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_016 EDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKT
         600       610       620       630       640       650     

              710       720       730       740       750       760
pF1KB1 HIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSS
         660       670       680       690       700       710     

              770       780       790       800       810       820
pF1KB1 DLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPR
         720       730       740       750       760       770     

              830       840       850       860       870       880
pF1KB1 RETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSES
       ::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 RETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSES
         780       790       800       810       820       830     

              890       900       910       920       930       940
pF1KB1 LSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSR
         840       850       860       870       880       890     

              950       960       970       980       990      1000
pF1KB1 SPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEK
         900       910       920       930       940       950     

             1010      1020      1030      1040      1050      1060
pF1KB1 NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWN
         960       970       980       990      1000      1010     

             1070      1080      1090      1100      1110      1120
pF1KB1 KNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQ
        1020      1030      1040      1050      1060      1070     

             1130      1140      1150      1160      1170      1180
pF1KB1 QSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQE
        1080      1090      1100      1110      1120      1130     

             1190      1200      1210      1220      1230      1240
pF1KB1 EETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLM
        1140      1150      1160      1170      1180      1190     

             1250      1260      1270      1280      1290      1300
pF1KB1 NIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQ
        1200      1210      1220      1230      1240      1250     

             1310      1320      1330      1340      1350      1360
pF1KB1 LQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKV
        1260      1270      1280      1290      1300      1310     

             1370      1380      1390      1400      1410      1420
pF1KB1 SVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSK
        1320      1330      1340      1350      1360      1370     

             1430      1440      1450      1460   
pF1KB1 SGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
       :::::::::::::::::::::::::::::::::::::::::::
XP_016 SGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
        1380      1390      1400      1410        

>>XP_016875707 (OMIM: 603668) PREDICTED: protein SCAF11   (1436 aa)
 initn: 8953 init1: 8953 opt: 8957  Z-score: 4091.7  bits: 769.7 E(85289):    0
Smith-Waterman score: 9439; 99.1% identity (99.2% similar) in 1427 aa overlap (1-1417:1-1426)

               10        20        30        40        50        60
pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN
               10        20        30        40        50        60

               70                  80        90       100       110
pF1KB1 HVFCMTCILKWAE----------TLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK
       :::::::::::::          :::::::::::::::::::::::::::::::::::::
XP_016 HVFCMTCILKWAEELFIPIKTLETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK
               70        80        90       100       110       120

              120       130       140       150       160       170
pF1KB1 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI
              130       140       150       160       170       180

              180       190       200       210       220       230
pF1KB1 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE
              190       200       210       220       230       240

              240       250       260       270       280       290
pF1KB1 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA
              250       260       270       280       290       300

              300       310       320       330       340       350
pF1KB1 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG
              310       320       330       340       350       360

              360       370       380       390       400       410
pF1KB1 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET
              370       380       390       400       410       420

              420       430       440       450       460       470
pF1KB1 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV
              430       440       450       460       470       480

              480       490       500       510       520       530
pF1KB1 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS
              490       500       510       520       530       540

              540       550       560       570       580       590
pF1KB1 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV
              550       560       570       580       590       600

              600       610       620       630       640       650
pF1KB1 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD
              610       620       630       640       650       660

              660       670       680       690       700       710
pF1KB1 TFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS
       ::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS
              670       680       690       700       710       720

              720       730       740       750       760       770
pF1KB1 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV
              730       740       750       760       770       780

              780       790       800       810       820       830
pF1KB1 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS
              790       800       810       820       830       840

              840       850       860       870       880       890
pF1KB1 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRE
       ::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_016 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRE
              850       860       870       880       890       900

              900       910       920       930       940       950
pF1KB1 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK
              910       920       930       940       950       960

              960       970       980       990      1000      1010
pF1KB1 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP
              970       980       990      1000      1010      1020

             1020      1030      1040      1050      1060      1070
pF1KB1 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN
             1030      1040      1050      1060      1070      1080

             1080      1090      1100      1110      1120      1130
pF1KB1 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE
             1090      1100      1110      1120      1130      1140

             1140      1150      1160      1170      1180      1190
pF1KB1 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL
             1150      1160      1170      1180      1190      1200

             1200      1210      1220      1230      1240      1250
pF1KB1 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH
             1210      1220      1230      1240      1250      1260

             1260      1270      1280      1290      1300      1310
pF1KB1 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV
             1270      1280      1290      1300      1310      1320

             1320      1330      1340      1350      1360      1370
pF1KB1 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS
             1330      1340      1350      1360      1370      1380

             1380      1390      1400      1410      1420      1430
pF1KB1 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVA
       ::::::::::::::::::::::::::::::::::::::::::::: :             
XP_016 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDK-CVLLECSIQKM   
             1390      1400      1410      1420       1430         

             1440      1450      1460   
pF1KB1 NLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG




1463 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 02:05:58 2016 done: Fri Nov  4 02:06:01 2016
 Total Scan time: 17.620 Total Display time:  0.770

Function used was FASTA [36.3.4 Apr, 2011]
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