FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB1891, 1463 aa 1>>>pF1KB1891 1463 - 1463 aa - 1463 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.6011+/-0.000503; mu= -1.2494+/- 0.032 mean_var=483.5668+/-98.574, 0's: 0 Z-trim(121.4): 203 B-trim: 609 in 1/59 Lambda= 0.058324 statistics sampled from 37751 (37958) to 37751 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.445), width: 16 Scan time: 17.620 The best scores are: opt bits E(85289) NP_004710 (OMIM: 603668) protein SCAF11 [Homo sapi (1463) 9770 838.1 0 XP_005269287 (OMIM: 603668) PREDICTED: protein SCA (1463) 9770 838.1 0 XP_011537287 (OMIM: 603668) PREDICTED: protein SCA (1463) 9770 838.1 0 XP_011537286 (OMIM: 603668) PREDICTED: protein SCA (1479) 9770 838.1 0 XP_016875710 (OMIM: 603668) PREDICTED: protein SCA (1428) 9258 795.0 0 XP_016875708 (OMIM: 603668) PREDICTED: protein SCA (1473) 9258 795.0 0 XP_016875706 (OMIM: 603668) PREDICTED: protein SCA (1473) 9258 795.0 0 XP_016875712 (OMIM: 603668) PREDICTED: protein SCA (1411) 9251 794.4 0 XP_016875711 (OMIM: 603668) PREDICTED: protein SCA (1418) 9251 794.4 0 XP_016875707 (OMIM: 603668) PREDICTED: protein SCA (1436) 8957 769.7 0 XP_016875709 (OMIM: 603668) PREDICTED: protein SCA (1400) 8278 712.5 5.6e-204 XP_011518539 (OMIM: 611780) PREDICTED: PHD and RIN (1609) 524 60.2 1.6e-07 NP_001273512 (OMIM: 611780) PHD and RING finger do (1645) 524 60.2 1.6e-07 XP_005253084 (OMIM: 611780) PREDICTED: PHD and RIN (1646) 524 60.2 1.6e-07 NP_001273511 (OMIM: 611780) PHD and RING finger do (1647) 524 60.2 1.6e-07 XP_011518538 (OMIM: 611780) PREDICTED: PHD and RIN (1647) 524 60.2 1.6e-07 XP_005253082 (OMIM: 611780) PREDICTED: PHD and RIN (1648) 524 60.2 1.6e-07 NP_065952 (OMIM: 611780) PHD and RING finger domai (1648) 524 60.2 1.6e-07 NP_001273510 (OMIM: 611780) PHD and RING finger do (1649) 524 60.2 1.6e-07 XP_005266369 (OMIM: 616453) PREDICTED: zinc finger (1564) 339 44.6 0.0074 NP_055885 (OMIM: 616453) zinc finger CCCH domain-c (1564) 339 44.6 0.0074 NP_001317495 (OMIM: 616453) zinc finger CCCH domai (1668) 339 44.6 0.0078 NP_001317494 (OMIM: 616453) zinc finger CCCH domai (1668) 339 44.6 0.0078 NP_001317496 (OMIM: 616453) zinc finger CCCH domai (1668) 339 44.6 0.0078 XP_005266367 (OMIM: 616453) PREDICTED: zinc finger (1669) 339 44.6 0.0078 XP_016875968 (OMIM: 616453) PREDICTED: zinc finger (1669) 339 44.6 0.0078 XP_016875969 (OMIM: 616453) PREDICTED: zinc finger (1669) 339 44.6 0.0078 NP_001317493 (OMIM: 616453) zinc finger CCCH domai (1669) 339 44.6 0.0078 XP_016875966 (OMIM: 616453) PREDICTED: zinc finger (1669) 339 44.6 0.0078 NP_001070256 (OMIM: 616453) zinc finger CCCH domai (1669) 339 44.6 0.0078 XP_016875967 (OMIM: 616453) PREDICTED: zinc finger (1669) 339 44.6 0.0078 >>NP_004710 (OMIM: 603668) protein SCAF11 [Homo sapiens] (1463 aa) initn: 9770 init1: 9770 opt: 9770 Z-score: 4461.3 bits: 838.1 E(85289): 0 Smith-Waterman score: 9770; 99.9% identity (99.9% similar) in 1463 aa overlap (1-1463:1-1463) 10 20 30 40 50 60 pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDYNNI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: NP_004 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB1 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB1 RGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRENKRSQPRVKD ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: NP_004 RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB1 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB1 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB1 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB1 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB1 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB1 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB1 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB1 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB1 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY 1390 1400 1410 1420 1430 1440 1450 1460 pF1KB1 KYSRKGSQKKTLEEPVSTEKNIG ::::::::::::::::::::::: NP_004 KYSRKGSQKKTLEEPVSTEKNIG 1450 1460 >>XP_005269287 (OMIM: 603668) PREDICTED: protein SCAF11 (1463 aa) initn: 9770 init1: 9770 opt: 9770 Z-score: 4461.3 bits: 838.1 E(85289): 0 Smith-Waterman score: 9770; 99.9% identity (99.9% similar) in 1463 aa overlap (1-1463:1-1463) 10 20 30 40 50 60 pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDYNNI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_005 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB1 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB1 RGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRENKRSQPRVKD ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_005 RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB1 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB1 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB1 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB1 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB1 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB1 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB1 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB1 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB1 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY 1390 1400 1410 1420 1430 1440 1450 1460 pF1KB1 KYSRKGSQKKTLEEPVSTEKNIG ::::::::::::::::::::::: XP_005 KYSRKGSQKKTLEEPVSTEKNIG 1450 1460 >>XP_011537287 (OMIM: 603668) PREDICTED: protein SCAF11 (1463 aa) initn: 9770 init1: 9770 opt: 9770 Z-score: 4461.3 bits: 838.1 E(85289): 0 Smith-Waterman score: 9770; 99.9% identity (99.9% similar) in 1463 aa overlap (1-1463:1-1463) 10 20 30 40 50 60 pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB1 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB1 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB1 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB1 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB1 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB1 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB1 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB1 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB1 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB1 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDYNNI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_011 KTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB1 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPME 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB1 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDT 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB1 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB1 RGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRENKRSQPRVKD ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_011 RGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB1 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB1 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB1 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB1 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB1 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB1 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTG 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB1 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB1 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQ 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB1 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKY 1390 1400 1410 1420 1430 1440 1450 1460 pF1KB1 KYSRKGSQKKTLEEPVSTEKNIG ::::::::::::::::::::::: XP_011 KYSRKGSQKKTLEEPVSTEKNIG 1450 1460 >>XP_011537286 (OMIM: 603668) PREDICTED: protein SCAF11 (1479 aa) initn: 9770 init1: 9770 opt: 9770 Z-score: 4461.3 bits: 838.1 E(85289): 0 Smith-Waterman score: 9770; 99.9% identity (99.9% similar) in 1463 aa overlap (1-1463:17-1479) 10 20 30 40 pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPIC :::::::::::::::::::::::::::::::::::::::::::: XP_011 MIVSIFSNKETLFQREMKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPIC 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB1 LNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKK 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB1 QLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB1 KKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALI 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB1 RQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSC 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB1 KGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNS 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB1 GCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSND 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB1 SVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANY 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB1 DTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLE 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB1 KQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKI 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB1 TESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVE 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB1 IIATCDTFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQ ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQ 670 680 690 700 710 720 710 720 730 740 750 760 pF1KB1 IQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLAD 730 740 750 760 770 780 770 780 790 800 810 820 pF1KB1 EKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETG 790 800 810 820 830 840 830 840 850 860 870 880 pF1KB1 KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPR ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_011 KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPR 850 860 870 880 890 900 890 900 910 920 930 940 pF1KB1 RETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSR 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KB1 CRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIH 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KB1 LDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFG 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KB1 SGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYK 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KB1 RKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETS 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KB1 GQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQR 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KB1 NPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGI 1270 1280 1290 1300 1310 1320 1310 1320 1330 1340 1350 1360 pF1KB1 PSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAV 1330 1340 1350 1360 1370 1380 1370 1380 1390 1400 1410 1420 pF1KB1 EASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEV 1390 1400 1410 1420 1430 1440 1430 1440 1450 1460 pF1KB1 NSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG ::::::::::::::::::::::::::::::::::::::: XP_011 NSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG 1450 1460 1470 >>XP_016875710 (OMIM: 603668) PREDICTED: protein SCAF11 (1428 aa) initn: 9255 init1: 9255 opt: 9258 Z-score: 4228.6 bits: 795.0 E(85289): 0 Smith-Waterman score: 9258; 99.6% identity (99.8% similar) in 1395 aa overlap (69-1463:34-1428) 40 50 60 70 80 90 pF1KB1 DRCPICLNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYV .: :::::::::::::::::::::::::: XP_016 HPFFQLQVHLSHNLYPDVHVPGFSRELFIPIKTLETLASCPIDRKPFQAVFKFSALEGYV 10 20 30 40 50 60 100 110 120 130 140 150 pF1KB1 KVQVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVQVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSL 70 80 90 100 110 120 160 170 180 190 200 210 pF1KB1 YSETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEAS 130 140 150 160 170 180 220 230 240 250 260 270 pF1KB1 EISALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EISALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFE 190 200 210 220 230 240 280 290 300 310 320 330 pF1KB1 HFGTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HFGTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRS 250 260 270 280 290 300 340 350 360 370 380 390 pF1KB1 PISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPE 310 320 330 340 350 360 400 410 420 430 440 450 pF1KB1 KSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESE 370 380 390 400 410 420 460 470 480 490 500 510 pF1KB1 KHTANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHTANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEK 430 440 450 460 470 480 520 530 540 550 560 570 pF1KB1 GGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESV 490 500 510 520 530 540 580 590 600 610 620 630 pF1KB1 VNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHV 550 560 570 580 590 600 640 650 660 670 680 690 pF1KB1 ETEDVEIIATCDTFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELP ::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::: XP_016 ETEDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELP 610 620 630 640 650 660 700 710 720 730 740 750 pF1KB1 KTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMP 670 680 690 700 710 720 760 770 780 790 800 810 pF1KB1 SSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPS 730 740 750 760 770 780 820 830 840 850 860 870 pF1KB1 PRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRS ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_016 PRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRS 790 800 810 820 830 840 880 890 900 910 920 930 pF1KB1 ESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSH 850 860 870 880 890 900 940 950 960 970 980 990 pF1KB1 SRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRK 910 920 930 940 950 960 1000 1010 1020 1030 1040 1050 pF1KB1 EKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNS 970 980 990 1000 1010 1020 1060 1070 1080 1090 1100 1110 pF1KB1 WNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFV 1030 1040 1050 1060 1070 1080 1120 1130 1140 1150 1160 1170 pF1KB1 EQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMK 1090 1100 1110 1120 1130 1140 1180 1190 1200 1210 1220 1230 pF1KB1 QEEETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEEETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAP 1150 1160 1170 1180 1190 1200 1240 1250 1260 1270 1280 1290 pF1KB1 LMNIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMNIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDG 1210 1220 1230 1240 1250 1260 1300 1310 1320 1330 1340 1350 pF1KB1 KQLQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQLQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAES 1270 1280 1290 1300 1310 1320 1360 1370 1380 1390 1400 1410 pF1KB1 KVSVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVSVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCH 1330 1340 1350 1360 1370 1380 1420 1430 1440 1450 1460 pF1KB1 SKSGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG ::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKSGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG 1390 1400 1410 1420 >>XP_016875708 (OMIM: 603668) PREDICTED: protein SCAF11 (1473 aa) initn: 9255 init1: 9255 opt: 9258 Z-score: 4228.5 bits: 795.0 E(85289): 0 Smith-Waterman score: 9740; 99.2% identity (99.3% similar) in 1473 aa overlap (1-1463:1-1473) 10 20 30 40 50 60 pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN 10 20 30 40 50 60 70 80 90 100 110 pF1KB1 HVFCMTCILKWAE----------TLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK ::::::::::::: ::::::::::::::::::::::::::::::::::::: XP_016 HVFCMTCILKWAEELFIPIKTLETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB1 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB1 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB1 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB1 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB1 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB1 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB1 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB1 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB1 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB1 TFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB1 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB1 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB1 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRE ::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: XP_016 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRE 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB1 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB1 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB1 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB1 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB1 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB1 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB1 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB1 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB1 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVA 1390 1400 1410 1420 1430 1440 1440 1450 1460 pF1KB1 NLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG ::::::::::::::::::::::::::::::::: XP_016 NLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG 1450 1460 1470 >>XP_016875706 (OMIM: 603668) PREDICTED: protein SCAF11 (1473 aa) initn: 9255 init1: 9255 opt: 9258 Z-score: 4228.5 bits: 795.0 E(85289): 0 Smith-Waterman score: 9740; 99.2% identity (99.3% similar) in 1473 aa overlap (1-1463:1-1473) 10 20 30 40 50 60 pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN 10 20 30 40 50 60 70 80 90 100 110 pF1KB1 HVFCMTCILKWAE----------TLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK ::::::::::::: ::::::::::::::::::::::::::::::::::::: XP_016 HVFCMTCILKWAEELFIPIKTLETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB1 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB1 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB1 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB1 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB1 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB1 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB1 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB1 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB1 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB1 TFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB1 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB1 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB1 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRE ::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: XP_016 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRE 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB1 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB1 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB1 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB1 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB1 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB1 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB1 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB1 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB1 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVA 1390 1400 1410 1420 1430 1440 1440 1450 1460 pF1KB1 NLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG ::::::::::::::::::::::::::::::::: XP_016 NLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG 1450 1460 1470 >>XP_016875712 (OMIM: 603668) PREDICTED: protein SCAF11 (1411 aa) initn: 9251 init1: 9251 opt: 9251 Z-score: 4225.5 bits: 794.4 E(85289): 0 Smith-Waterman score: 9251; 99.6% identity (99.9% similar) in 1393 aa overlap (71-1463:19-1411) 50 60 70 80 90 100 pF1KB1 CPICLNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKV ...::::::::::::::::::::::::::: XP_016 MGRVHLSHNLYPDVHVPGFSRTLASCPIDRKPFQAVFKFSALEGYVKV 10 20 30 40 110 120 130 140 150 160 pF1KB1 QVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYS 50 60 70 80 90 100 170 180 190 200 210 220 pF1KB1 ETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEI 110 120 130 140 150 160 230 240 250 260 270 280 pF1KB1 SALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHF 170 180 190 200 210 220 290 300 310 320 330 340 pF1KB1 GTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPI 230 240 250 260 270 280 350 360 370 380 390 400 pF1KB1 SDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKS 290 300 310 320 330 340 410 420 430 440 450 460 pF1KB1 SSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKH 350 360 370 380 390 400 470 480 490 500 510 520 pF1KB1 TANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGG 410 420 430 440 450 460 530 540 550 560 570 580 pF1KB1 DPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVN 470 480 490 500 510 520 590 600 610 620 630 640 pF1KB1 EEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVET 530 540 550 560 570 580 650 660 670 680 690 700 pF1KB1 EDVEIIATCDTFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKT ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_016 EDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKT 590 600 610 620 630 640 710 720 730 740 750 760 pF1KB1 HIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSS 650 660 670 680 690 700 770 780 790 800 810 820 pF1KB1 DLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPR 710 720 730 740 750 760 830 840 850 860 870 880 pF1KB1 RETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSES ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_016 RETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSES 770 780 790 800 810 820 890 900 910 920 930 940 pF1KB1 LSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSR 830 840 850 860 870 880 950 960 970 980 990 1000 pF1KB1 SPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEK 890 900 910 920 930 940 1010 1020 1030 1040 1050 1060 pF1KB1 NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWN 950 960 970 980 990 1000 1070 1080 1090 1100 1110 1120 pF1KB1 KNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQ 1010 1020 1030 1040 1050 1060 1130 1140 1150 1160 1170 1180 pF1KB1 QSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQE 1070 1080 1090 1100 1110 1120 1190 1200 1210 1220 1230 1240 pF1KB1 EETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLM 1130 1140 1150 1160 1170 1180 1250 1260 1270 1280 1290 1300 pF1KB1 NIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQ 1190 1200 1210 1220 1230 1240 1310 1320 1330 1340 1350 1360 pF1KB1 LQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKV 1250 1260 1270 1280 1290 1300 1370 1380 1390 1400 1410 1420 pF1KB1 SVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSK 1310 1320 1330 1340 1350 1360 1430 1440 1450 1460 pF1KB1 SGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG ::::::::::::::::::::::::::::::::::::::::::: XP_016 SGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG 1370 1380 1390 1400 1410 >>XP_016875711 (OMIM: 603668) PREDICTED: protein SCAF11 (1418 aa) initn: 9251 init1: 9251 opt: 9251 Z-score: 4225.5 bits: 794.4 E(85289): 0 Smith-Waterman score: 9251; 99.6% identity (99.9% similar) in 1393 aa overlap (71-1463:26-1418) 50 60 70 80 90 100 pF1KB1 CPICLNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKV ...::::::::::::::::::::::::::: XP_016 MVLHPFFQLQVHLSHNLYPDVHVPGFSRTLASCPIDRKPFQAVFKFSALEGYVKV 10 20 30 40 50 110 120 130 140 150 160 pF1KB1 QVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYS 60 70 80 90 100 110 170 180 190 200 210 220 pF1KB1 ETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEI 120 130 140 150 160 170 230 240 250 260 270 280 pF1KB1 SALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHF 180 190 200 210 220 230 290 300 310 320 330 340 pF1KB1 GTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPI 240 250 260 270 280 290 350 360 370 380 390 400 pF1KB1 SDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKS 300 310 320 330 340 350 410 420 430 440 450 460 pF1KB1 SSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKH 360 370 380 390 400 410 470 480 490 500 510 520 pF1KB1 TANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGG 420 430 440 450 460 470 530 540 550 560 570 580 pF1KB1 DPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVN 480 490 500 510 520 530 590 600 610 620 630 640 pF1KB1 EEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVET 540 550 560 570 580 590 650 660 670 680 690 700 pF1KB1 EDVEIIATCDTFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKT ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_016 EDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKT 600 610 620 630 640 650 710 720 730 740 750 760 pF1KB1 HIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSS 660 670 680 690 700 710 770 780 790 800 810 820 pF1KB1 DLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPR 720 730 740 750 760 770 830 840 850 860 870 880 pF1KB1 RETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSES ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_016 RETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSES 780 790 800 810 820 830 890 900 910 920 930 940 pF1KB1 LSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSR 840 850 860 870 880 890 950 960 970 980 990 1000 pF1KB1 SPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEK 900 910 920 930 940 950 1010 1020 1030 1040 1050 1060 pF1KB1 NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWN 960 970 980 990 1000 1010 1070 1080 1090 1100 1110 1120 pF1KB1 KNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQ 1020 1030 1040 1050 1060 1070 1130 1140 1150 1160 1170 1180 pF1KB1 QSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQE 1080 1090 1100 1110 1120 1130 1190 1200 1210 1220 1230 1240 pF1KB1 EETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLM 1140 1150 1160 1170 1180 1190 1250 1260 1270 1280 1290 1300 pF1KB1 NIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQ 1200 1210 1220 1230 1240 1250 1310 1320 1330 1340 1350 1360 pF1KB1 LQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKV 1260 1270 1280 1290 1300 1310 1370 1380 1390 1400 1410 1420 pF1KB1 SVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSK 1320 1330 1340 1350 1360 1370 1430 1440 1450 1460 pF1KB1 SGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG ::::::::::::::::::::::::::::::::::::::::::: XP_016 SGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG 1380 1390 1400 1410 >>XP_016875707 (OMIM: 603668) PREDICTED: protein SCAF11 (1436 aa) initn: 8953 init1: 8953 opt: 8957 Z-score: 4091.7 bits: 769.7 E(85289): 0 Smith-Waterman score: 9439; 99.1% identity (99.2% similar) in 1427 aa overlap (1-1417:1-1426) 10 20 30 40 50 60 pF1KB1 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCN 10 20 30 40 50 60 70 80 90 100 110 pF1KB1 HVFCMTCILKWAE----------TLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK ::::::::::::: ::::::::::::::::::::::::::::::::::::: XP_016 HVFCMTCILKWAEELFIPIKTLETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB1 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB1 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB1 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB1 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB1 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEET 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB1 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERV 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB1 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQIS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB1 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB1 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCD 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB1 TFGNEDYNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFS 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB1 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETV 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB1 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKS 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB1 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRYTTRESRRSESLSPRRETSRE ::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::: XP_016 QSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRE 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB1 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB1 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDP 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB1 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSN 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB1 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQE 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB1 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB1 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIH 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB1 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHV 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB1 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADS 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB1 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVA ::::::::::::::::::::::::::::::::::::::::::::: : XP_016 SKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDK-CVLLECSIQKM 1390 1400 1410 1420 1430 1440 1450 1460 pF1KB1 NLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG 1463 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:05:58 2016 done: Fri Nov 4 02:06:01 2016 Total Scan time: 17.620 Total Display time: 0.770 Function used was FASTA [36.3.4 Apr, 2011]