Result of FASTA (omim) for
pF1KB3002
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3002, 575 aa
1>>>pF1KB3002 575 - 575 aa - 575 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8957+/-0.000341; mu= -2.0485+/- 0.021
mean_var=206.4517+/-42.138, 0's: 0 Z-trim(121.2): 66 B-trim: 0 in 0/61
Lambda= 0.089262
statistics sampled from 37454 (37520) to 37454 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.44), width: 16
Scan time: 11.930
The best scores are: opt bits E(85289)
XP_011537953 (OMIM: 606343) PREDICTED: DNA polymer ( 575) 3868 510.6 5.4e-144
NP_001167555 (OMIM: 606343) DNA polymerase lambda ( 575) 3868 510.6 5.4e-144
NP_037406 (OMIM: 606343) DNA polymerase lambda iso ( 575) 3868 510.6 5.4e-144
XP_011537954 (OMIM: 606343) PREDICTED: DNA polymer ( 582) 3844 507.5 4.7e-143
XP_011537952 (OMIM: 606343) PREDICTED: DNA polymer ( 582) 3844 507.5 4.7e-143
XP_011537955 (OMIM: 606343) PREDICTED: DNA polymer ( 582) 3844 507.5 4.7e-143
XP_011537959 (OMIM: 606343) PREDICTED: DNA polymer ( 494) 3256 431.8 2.5e-120
XP_016871580 (OMIM: 606343) PREDICTED: DNA polymer ( 406) 2577 344.3 4.5e-94
XP_011537961 (OMIM: 606343) PREDICTED: DNA polymer ( 413) 2553 341.2 3.9e-93
XP_011537962 (OMIM: 606343) PREDICTED: DNA polymer ( 413) 2553 341.2 3.9e-93
XP_016871578 (OMIM: 606343) PREDICTED: DNA polymer ( 413) 2553 341.2 3.9e-93
XP_016871574 (OMIM: 606343) PREDICTED: DNA polymer ( 474) 2000 270.0 1.2e-71
XP_016871573 (OMIM: 606343) PREDICTED: DNA polymer ( 481) 2000 270.0 1.2e-71
XP_016871575 (OMIM: 606343) PREDICTED: DNA polymer ( 469) 1887 255.5 2.8e-67
XP_006717839 (OMIM: 606343) PREDICTED: DNA polymer ( 314) 1875 253.9 5.8e-67
XP_006717838 (OMIM: 606343) PREDICTED: DNA polymer ( 314) 1875 253.9 5.8e-67
NP_001167556 (OMIM: 606343) DNA polymerase lambda ( 483) 1875 253.9 8.5e-67
XP_011537957 (OMIM: 606343) PREDICTED: DNA polymer ( 483) 1875 253.9 8.5e-67
NP_001295311 (OMIM: 606343) DNA polymerase lambda ( 300) 1870 253.2 8.7e-67
XP_006717840 (OMIM: 606343) PREDICTED: DNA polymer ( 300) 1870 253.2 8.7e-67
XP_011537964 (OMIM: 606343) PREDICTED: DNA polymer ( 321) 1851 250.8 5e-66
XP_011537965 (OMIM: 606343) PREDICTED: DNA polymer ( 321) 1851 250.8 5e-66
XP_016871582 (OMIM: 606343) PREDICTED: DNA polymer ( 307) 1846 250.1 7.6e-66
XP_011537967 (OMIM: 606343) PREDICTED: DNA polymer ( 307) 1846 250.1 7.6e-66
XP_011537966 (OMIM: 606343) PREDICTED: DNA polymer ( 307) 1846 250.1 7.6e-66
XP_011537968 (OMIM: 606343) PREDICTED: DNA polymer ( 307) 1846 250.1 7.6e-66
XP_011537969 (OMIM: 606343) PREDICTED: DNA polymer ( 267) 1790 242.9 9.9e-64
XP_016871576 (OMIM: 606343) PREDICTED: DNA polymer ( 389) 1399 192.6 2e-48
XP_011537956 (OMIM: 606343) PREDICTED: DNA polymer ( 490) 1386 191.0 7.8e-48
XP_011537958 (OMIM: 606343) PREDICTED: DNA polymer ( 476) 1303 180.3 1.3e-44
XP_016871579 (OMIM: 606343) PREDICTED: DNA polymer ( 359) 926 131.7 4e-30
XP_016871581 (OMIM: 606343) PREDICTED: DNA polymer ( 366) 926 131.7 4.1e-30
XP_016871577 (OMIM: 606343) PREDICTED: DNA polymer ( 366) 926 131.7 4.1e-30
NP_002681 (OMIM: 174760) DNA polymerase beta [Homo ( 335) 653 96.5 1.4e-19
XP_005273592 (OMIM: 174760) PREDICTED: DNA polymer ( 370) 494 76.1 2.3e-13
XP_005273595 (OMIM: 174760) PREDICTED: DNA polymer ( 221) 473 73.3 9.5e-13
XP_016869072 (OMIM: 174760) PREDICTED: DNA polymer ( 221) 473 73.3 9.5e-13
NP_037416 (OMIM: 606344) DNA-directed DNA/RNA poly ( 494) 471 73.1 2.3e-12
XP_006715755 (OMIM: 606344) PREDICTED: DNA-directe ( 588) 471 73.2 2.7e-12
XP_011513581 (OMIM: 606344) PREDICTED: DNA-directe ( 499) 451 70.6 1.4e-11
XP_011513577 (OMIM: 606344) PREDICTED: DNA-directe ( 593) 451 70.6 1.6e-11
XP_005273594 (OMIM: 174760) PREDICTED: DNA polymer ( 306) 402 64.2 7.2e-10
XP_006716416 (OMIM: 174760) PREDICTED: DNA polymer ( 181) 378 61.0 3.8e-09
XP_005273597 (OMIM: 174760) PREDICTED: DNA polymer ( 181) 378 61.0 3.8e-09
XP_005273596 (OMIM: 174760) PREDICTED: DNA polymer ( 181) 378 61.0 3.8e-09
XP_016869073 (OMIM: 174760) PREDICTED: DNA polymer ( 181) 378 61.0 3.8e-09
NP_001017520 (OMIM: 187410) DNA nucleotidylexotran ( 508) 344 56.8 2e-07
NP_004079 (OMIM: 187410) DNA nucleotidylexotransfe ( 509) 344 56.8 2e-07
XP_006715759 (OMIM: 606344) PREDICTED: DNA-directe ( 498) 319 53.6 1.8e-06
NP_001271260 (OMIM: 606344) DNA-directed DNA/RNA p ( 457) 318 53.4 1.8e-06
>>XP_011537953 (OMIM: 606343) PREDICTED: DNA polymerase (575 aa)
initn: 3868 init1: 3868 opt: 3868 Z-score: 2706.1 bits: 510.6 E(85289): 5.4e-144
Smith-Waterman score: 3868; 100.0% identity (100.0% similar) in 575 aa overlap (1-575:1-575)
10 20 30 40 50 60
pF1KB3 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 GPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNT
490 500 510 520 530 540
550 560 570
pF1KB3 HGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
:::::::::::::::::::::::::::::::::::
XP_011 HGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
550 560 570
>>NP_001167555 (OMIM: 606343) DNA polymerase lambda isof (575 aa)
initn: 3868 init1: 3868 opt: 3868 Z-score: 2706.1 bits: 510.6 E(85289): 5.4e-144
Smith-Waterman score: 3868; 100.0% identity (100.0% similar) in 575 aa overlap (1-575:1-575)
10 20 30 40 50 60
pF1KB3 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 GPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNT
490 500 510 520 530 540
550 560 570
pF1KB3 HGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
:::::::::::::::::::::::::::::::::::
NP_001 HGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
550 560 570
>>NP_037406 (OMIM: 606343) DNA polymerase lambda isoform (575 aa)
initn: 3868 init1: 3868 opt: 3868 Z-score: 2706.1 bits: 510.6 E(85289): 5.4e-144
Smith-Waterman score: 3868; 100.0% identity (100.0% similar) in 575 aa overlap (1-575:1-575)
10 20 30 40 50 60
pF1KB3 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 GPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNT
490 500 510 520 530 540
550 560 570
pF1KB3 HGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
:::::::::::::::::::::::::::::::::::
NP_037 HGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
550 560 570
>>XP_011537954 (OMIM: 606343) PREDICTED: DNA polymerase (582 aa)
initn: 3854 init1: 3040 opt: 3844 Z-score: 2689.3 bits: 507.5 E(85289): 4.7e-143
Smith-Waterman score: 3844; 98.8% identity (98.8% similar) in 582 aa overlap (1-575:1-582)
10 20 30 40 50 60
pF1KB3 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
370 380 390 400 410 420
430 440 450 460 470
pF1KB3 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQE-------GFLTDDLVSQEENGQQQKY
:::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_011 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEAVPSVGPGFLTDDLVSQEENGQQQKY
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB3 LGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALS
490 500 510 520 530 540
540 550 560 570
pF1KB3 TAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
::::::::::::::::::::::::::::::::::::::::::
XP_011 TAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
550 560 570 580
>>XP_011537952 (OMIM: 606343) PREDICTED: DNA polymerase (582 aa)
initn: 3854 init1: 3040 opt: 3844 Z-score: 2689.3 bits: 507.5 E(85289): 4.7e-143
Smith-Waterman score: 3844; 98.8% identity (98.8% similar) in 582 aa overlap (1-575:1-582)
10 20 30 40 50 60
pF1KB3 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
370 380 390 400 410 420
430 440 450 460 470
pF1KB3 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQE-------GFLTDDLVSQEENGQQQKY
:::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_011 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEAVPSVGPGFLTDDLVSQEENGQQQKY
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB3 LGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALS
490 500 510 520 530 540
540 550 560 570
pF1KB3 TAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
::::::::::::::::::::::::::::::::::::::::::
XP_011 TAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
550 560 570 580
>>XP_011537955 (OMIM: 606343) PREDICTED: DNA polymerase (582 aa)
initn: 3854 init1: 3040 opt: 3844 Z-score: 2689.3 bits: 507.5 E(85289): 4.7e-143
Smith-Waterman score: 3844; 98.8% identity (98.8% similar) in 582 aa overlap (1-575:1-582)
10 20 30 40 50 60
pF1KB3 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
370 380 390 400 410 420
430 440 450 460 470
pF1KB3 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQE-------GFLTDDLVSQEENGQQQKY
:::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_011 GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEAVPSVGPGFLTDDLVSQEENGQQQKY
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB3 LGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALS
490 500 510 520 530 540
540 550 560 570
pF1KB3 TAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
::::::::::::::::::::::::::::::::::::::::::
XP_011 TAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
550 560 570 580
>>XP_011537959 (OMIM: 606343) PREDICTED: DNA polymerase (494 aa)
initn: 3266 init1: 2452 opt: 3256 Z-score: 2281.2 bits: 431.8 E(85289): 2.5e-120
Smith-Waterman score: 3256; 98.6% identity (98.6% similar) in 494 aa overlap (89-575:1-494)
60 70 80 90 100 110
pF1KB3 ELFEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLC
::::::::::::::::::::::::::::::
XP_011 MDYERALRLLRLPQLPPGAQLVKSAWLSLC
10 20 30
120 130 140 150 160 170
pF1KB3 LQERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSP
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB3 PQKAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQKAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDK
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB3 WVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQE
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB3 ACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFR
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB3 SLEDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLEDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSY
280 290 300 310 320 330
420 430 440 450 460 470
pF1KB3 RRGKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQE-------GFLTDDLVSQEENGQQQ
:::::::::::::::::::::::::::::::::::: :::::::::::::::::
XP_011 RRGKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEAVPSVGPGFLTDDLVSQEENGQQQ
340 350 360 370 380 390
480 490 500 510 520 530
pF1KB3 KYLGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYLGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHA
400 410 420 430 440 450
540 550 560 570
pF1KB3 LSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
460 470 480 490
>>XP_016871580 (OMIM: 606343) PREDICTED: DNA polymerase (406 aa)
initn: 2577 init1: 2577 opt: 2577 Z-score: 1810.0 bits: 344.3 E(85289): 4.5e-94
Smith-Waterman score: 2577; 99.2% identity (99.7% similar) in 387 aa overlap (189-575:20-406)
160 170 180 190 200 210
pF1KB3 EALLQTALSPPPPPTRPVSPPQKAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGH
. .:::::::::::::::::::::::::::
XP_016 MLMHHQKYLQRFLGGKREKKQKPISDDEASDGEETQVSAADLEALISGH
10 20 30 40
220 230 240 250 260 270
pF1KB3 YPTSLEGDCEPSPAPAVLDKWVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPTSLEGDCEPSPAPAVLDKWVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALG
50 60 70 80 90 100
280 290 300 310 320 330
pF1KB3 YAKAINALKSFHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAKAINALKSFHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELF
110 120 130 140 150 160
340 350 360 370 380 390
pF1KB3 SNIWGAGTKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNIWGAGTKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQT
170 180 190 200 210 220
400 410 420 430 440 450
pF1KB3 VQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLT
230 240 250 260 270 280
460 470 480 490 500 510
pF1KB3 DDLVSQEENGQQQKYLGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDLVSQEENGQQQKYLGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRA
290 300 310 320 330 340
520 530 540 550 560 570
pF1KB3 LAKTKGMSLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKTKGMSLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
350 360 370 380 390 400
>>XP_011537961 (OMIM: 606343) PREDICTED: DNA polymerase (413 aa)
initn: 2563 init1: 1749 opt: 2553 Z-score: 1793.2 bits: 341.2 E(85289): 3.9e-93
Smith-Waterman score: 2553; 97.5% identity (98.0% similar) in 394 aa overlap (189-575:20-413)
160 170 180 190 200 210
pF1KB3 EALLQTALSPPPPPTRPVSPPQKAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGH
. .:::::::::::::::::::::::::::
XP_011 MLMHHQKYLQRFLGGKREKKQKPISDDEASDGEETQVSAADLEALISGH
10 20 30 40
220 230 240 250 260 270
pF1KB3 YPTSLEGDCEPSPAPAVLDKWVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPTSLEGDCEPSPAPAVLDKWVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALG
50 60 70 80 90 100
280 290 300 310 320 330
pF1KB3 YAKAINALKSFHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAKAINALKSFHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELF
110 120 130 140 150 160
340 350 360 370 380 390
pF1KB3 SNIWGAGTKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNIWGAGTKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQT
170 180 190 200 210 220
400 410 420 430 440 450
pF1KB3 VQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQE----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEAVPS
230 240 250 260 270 280
460 470 480 490 500 510
pF1KB3 ---GFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGPGFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAH
290 300 310 320 330 340
520 530 540 550 560 570
pF1KB3 FNRSMRALAKTKGMSLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNRSMRALAKTKGMSLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPA
350 360 370 380 390 400
pF1KB3 ERDW
::::
XP_011 ERDW
410
>>XP_011537962 (OMIM: 606343) PREDICTED: DNA polymerase (413 aa)
initn: 2563 init1: 1749 opt: 2553 Z-score: 1793.2 bits: 341.2 E(85289): 3.9e-93
Smith-Waterman score: 2553; 97.5% identity (98.0% similar) in 394 aa overlap (189-575:20-413)
160 170 180 190 200 210
pF1KB3 EALLQTALSPPPPPTRPVSPPQKAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGH
. .:::::::::::::::::::::::::::
XP_011 MLMHHQKYLQRFLGGKREKKQKPISDDEASDGEETQVSAADLEALISGH
10 20 30 40
220 230 240 250 260 270
pF1KB3 YPTSLEGDCEPSPAPAVLDKWVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPTSLEGDCEPSPAPAVLDKWVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALG
50 60 70 80 90 100
280 290 300 310 320 330
pF1KB3 YAKAINALKSFHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAKAINALKSFHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELF
110 120 130 140 150 160
340 350 360 370 380 390
pF1KB3 SNIWGAGTKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNIWGAGTKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQT
170 180 190 200 210 220
400 410 420 430 440 450
pF1KB3 VQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQE----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEAVPS
230 240 250 260 270 280
460 470 480 490 500 510
pF1KB3 ---GFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGPGFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRRLDIIVVPYSEFACALLYFTGSAH
290 300 310 320 330 340
520 530 540 550 560 570
pF1KB3 FNRSMRALAKTKGMSLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNRSMRALAKTKGMSLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPA
350 360 370 380 390 400
pF1KB3 ERDW
::::
XP_011 ERDW
410
575 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:02:27 2016 done: Thu Nov 3 12:02:29 2016
Total Scan time: 11.930 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]