FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3016, 779 aa 1>>>pF1KB3016 779 - 779 aa - 779 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0026+/-0.000377; mu= 21.9364+/- 0.023 mean_var=68.0343+/-13.582, 0's: 0 Z-trim(113.2): 86 B-trim: 279 in 2/53 Lambda= 0.155493 statistics sampled from 22357 (22448) to 22357 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.263), width: 16 Scan time: 12.430 The best scores are: opt bits E(85289) NP_078888 (OMIM: 607570) probable ATP-dependent RN ( 779) 5224 1181.5 0 XP_016880569 (OMIM: 607570) PREDICTED: probable AT ( 723) 4615 1044.8 0 XP_011523556 (OMIM: 607570) PREDICTED: probable AT ( 680) 4569 1034.5 0 NP_001159773 (OMIM: 607570) probable ATP-dependent ( 702) 4306 975.5 0 XP_016880572 (OMIM: 607570) PREDICTED: probable AT ( 640) 4292 972.3 0 XP_016880571 (OMIM: 607570) PREDICTED: probable AT ( 640) 4292 972.3 0 XP_006722146 (OMIM: 607570) PREDICTED: probable AT ( 752) 2961 673.8 7.3e-193 XP_011523555 (OMIM: 607570) PREDICTED: probable AT ( 718) 2549 581.4 4.7e-165 XP_016880570 (OMIM: 607570) PREDICTED: probable AT ( 653) 2306 526.8 1.1e-148 NP_001349 (OMIM: 603403) pre-mRNA-splicing factor ( 795) 1078 251.4 1.1e-65 NP_001309145 (OMIM: 600396) ATP-dependent RNA heli ( 945) 913 214.5 1.7e-54 NP_001309146 (OMIM: 600396) ATP-dependent RNA heli (1129) 913 214.5 2e-54 NP_001309149 (OMIM: 600396) ATP-dependent RNA heli (1152) 913 214.5 2e-54 NP_001309148 (OMIM: 600396) ATP-dependent RNA heli (1169) 913 214.5 2.1e-54 NP_001309147 (OMIM: 600396) ATP-dependent RNA heli (1179) 913 214.5 2.1e-54 NP_001289552 (OMIM: 600396) ATP-dependent RNA heli (1181) 913 214.5 2.1e-54 NP_001309150 (OMIM: 600396) ATP-dependent RNA heli (1218) 913 214.5 2.1e-54 NP_004932 (OMIM: 600396) ATP-dependent RNA helicas (1220) 913 214.5 2.1e-54 XP_011513243 (OMIM: 603405) PREDICTED: putative pr ( 524) 876 206.0 3.5e-52 XP_011513242 (OMIM: 603405) PREDICTED: putative pr ( 560) 876 206.0 3.7e-52 XP_011513240 (OMIM: 603405) PREDICTED: putative pr ( 742) 876 206.1 4.6e-52 XP_011513241 (OMIM: 603405) PREDICTED: putative pr ( 742) 876 206.1 4.6e-52 NP_001157711 (OMIM: 603405) putative pre-mRNA-spli ( 981) 876 206.2 5.7e-52 NP_003578 (OMIM: 603405) putative pre-mRNA-splicin (1041) 876 206.2 5.9e-52 XP_005256326 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1192) 847 199.7 6e-50 XP_016879402 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1192) 847 199.7 6e-50 XP_011521787 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1227) 847 199.7 6.1e-50 NP_054722 (OMIM: 605584) pre-mRNA-splicing factor (1227) 847 199.7 6.1e-50 XP_011521786 (OMIM: 605584) PREDICTED: pre-mRNA-sp (1227) 847 199.7 6.1e-50 NP_055781 (OMIM: 616423) putative ATP-dependent RN (1155) 812 191.9 1.3e-47 XP_016861406 (OMIM: 616423) PREDICTED: putative AT (1155) 812 191.9 1.3e-47 XP_016861405 (OMIM: 616423) PREDICTED: putative AT (1157) 812 191.9 1.4e-47 XP_006713096 (OMIM: 616423) PREDICTED: putative AT (1162) 812 191.9 1.4e-47 XP_016861404 (OMIM: 616423) PREDICTED: putative AT (1162) 812 191.9 1.4e-47 NP_001317919 (OMIM: 616423) putative ATP-dependent (1166) 812 191.9 1.4e-47 XP_011531799 (OMIM: 616423) PREDICTED: putative AT (1166) 812 191.9 1.4e-47 XP_011531798 (OMIM: 616423) PREDICTED: putative AT (1166) 812 191.9 1.4e-47 XP_011531800 (OMIM: 616423) PREDICTED: putative AT (1166) 812 191.9 1.4e-47 XP_011531797 (OMIM: 616423) PREDICTED: putative AT (1194) 812 191.9 1.4e-47 NP_619520 (OMIM: 616423) putative ATP-dependent RN (1194) 812 191.9 1.4e-47 XP_011531796 (OMIM: 616423) PREDICTED: putative AT (1194) 812 191.9 1.4e-47 XP_011531795 (OMIM: 616423) PREDICTED: putative AT (1228) 812 191.9 1.4e-47 XP_016861403 (OMIM: 616423) PREDICTED: putative AT (1238) 812 191.9 1.4e-47 XP_011531793 (OMIM: 616423) PREDICTED: putative AT (1265) 812 191.9 1.4e-47 XP_011531794 (OMIM: 616423) PREDICTED: putative AT (1265) 812 191.9 1.4e-47 XP_011531792 (OMIM: 616423) PREDICTED: putative AT (1265) 812 191.9 1.4e-47 NP_001186628 (OMIM: 614405) putative ATP-dependent ( 534) 710 168.7 5.7e-41 NP_064547 (OMIM: 614405) putative ATP-dependent RN ( 707) 660 157.6 1.7e-37 XP_011525852 (OMIM: 615475) PREDICTED: probable AT (1143) 643 153.9 3.5e-36 NP_055496 (OMIM: 615475) probable ATP-dependent RN (1143) 643 153.9 3.5e-36 >>NP_078888 (OMIM: 607570) probable ATP-dependent RNA he (779 aa) initn: 5224 init1: 5224 opt: 5224 Z-score: 6326.9 bits: 1181.5 E(85289): 0 Smith-Waterman score: 5224; 100.0% identity (100.0% similar) in 779 aa overlap (1-779:1-779) 10 20 30 40 50 60 pF1KB3 MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 HVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 HVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR 670 680 690 700 710 720 730 740 750 760 770 pF1KB3 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG 730 740 750 760 770 >>XP_016880569 (OMIM: 607570) PREDICTED: probable ATP-de (723 aa) initn: 4846 init1: 4615 opt: 4615 Z-score: 5589.0 bits: 1044.8 E(85289): 0 Smith-Waterman score: 4738; 92.8% identity (92.8% similar) in 779 aa overlap (1-779:1-723) 10 20 30 40 50 60 pF1KB3 MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK ::::::::::::::::::::::::::::::::::::: XP_016 MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADR----------------------- 10 20 30 70 80 90 100 110 120 pF1KB3 KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE ::::::::::::::::::::::::::: XP_016 ---------------------------------GFSQHGMIGVTQPRKVAAISVAQRVAE 40 50 60 130 140 150 160 170 180 pF1KB3 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 70 80 90 100 110 120 190 200 210 220 230 240 pF1KB3 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB3 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB3 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 250 260 270 280 290 300 370 380 390 400 410 420 pF1KB3 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 310 320 330 340 350 360 430 440 450 460 470 480 pF1KB3 HVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVT 370 380 390 400 410 420 490 500 510 520 530 540 pF1KB3 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH 430 440 450 460 470 480 550 560 570 580 590 600 pF1KB3 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL 490 500 510 520 530 540 610 620 630 640 650 660 pF1KB3 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHE 550 560 570 580 590 600 670 680 690 700 710 720 pF1KB3 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR 610 620 630 640 650 660 730 740 750 760 770 pF1KB3 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG 670 680 690 700 710 720 >>XP_011523556 (OMIM: 607570) PREDICTED: probable ATP-de (680 aa) initn: 4569 init1: 4569 opt: 4569 Z-score: 5533.6 bits: 1034.5 E(85289): 0 Smith-Waterman score: 4569; 100.0% identity (100.0% similar) in 680 aa overlap (100-779:1-680) 70 80 90 100 110 120 pF1KB3 SFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSK :::::::::::::::::::::::::::::: XP_011 MIGVTQPRKVAAISVAQRVAEEMKCTLGSK 10 20 30 130 140 150 160 170 180 pF1KB3 VGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLL 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB3 KKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRD 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB3 RENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTT 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB3 LDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQL 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB3 NHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRT 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB3 SLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEF 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB3 PLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGG 400 410 420 430 440 450 550 560 570 580 590 600 pF1KB3 FNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPKE 460 470 480 490 500 510 610 620 630 640 650 660 pF1KB3 TFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWII 520 530 540 550 560 570 670 680 690 700 710 720 pF1KB3 FHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDARRRWTNKENV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDARRRWTNKENV 580 590 600 610 620 630 730 740 750 760 770 pF1KB3 KQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG 640 650 660 670 680 >>NP_001159773 (OMIM: 607570) probable ATP-dependent RNA (702 aa) initn: 4708 init1: 4290 opt: 4306 Z-score: 5214.5 bits: 975.5 E(85289): 0 Smith-Waterman score: 4558; 90.1% identity (90.1% similar) in 779 aa overlap (1-779:1-702) 10 20 30 40 50 60 pF1KB3 MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE ::::: NP_001 KIIQA------------------------------------------------------- 130 140 150 160 170 180 pF1KB3 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL :::::::::::::::::::::::::::::::::::::: NP_001 ----------------------ETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 70 80 90 100 190 200 210 220 230 240 pF1KB3 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB3 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB3 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 230 240 250 260 270 280 370 380 390 400 410 420 pF1KB3 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 290 300 310 320 330 340 430 440 450 460 470 480 pF1KB3 HVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVT 350 360 370 380 390 400 490 500 510 520 530 540 pF1KB3 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH 410 420 430 440 450 460 550 560 570 580 590 600 pF1KB3 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL 470 480 490 500 510 520 610 620 630 640 650 660 pF1KB3 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHE 530 540 550 560 570 580 670 680 690 700 710 720 pF1KB3 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR 590 600 610 620 630 640 730 740 750 760 770 pF1KB3 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG 650 660 670 680 690 700 >>XP_016880572 (OMIM: 607570) PREDICTED: probable ATP-de (640 aa) initn: 4292 init1: 4292 opt: 4292 Z-score: 5198.1 bits: 972.3 E(85289): 0 Smith-Waterman score: 4292; 99.8% identity (100.0% similar) in 638 aa overlap (142-779:3-640) 120 130 140 150 160 170 pF1KB3 ISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVII .::::::::::::::::::::::::::::: XP_016 MKQETAIKYMTDGCLLKHILGDPNLTKFSVII 10 20 30 180 190 200 210 220 230 pF1KB3 LDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIP 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB3 GRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCEL 100 110 120 130 140 150 300 310 320 330 340 350 pF1KB3 LFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATS 160 170 180 190 200 210 360 370 380 390 400 410 pF1KB3 LTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSK 220 230 240 250 260 270 420 430 440 450 460 470 pF1KB3 DFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCD 280 290 300 310 320 330 480 490 500 510 520 530 pF1KB3 AIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPE 340 350 360 370 380 390 540 550 560 570 580 590 pF1KB3 YQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEA 400 410 420 430 440 450 600 610 620 630 640 650 pF1KB3 QLRELIRKLKQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLRELIRKLKQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVH 460 470 480 490 500 510 660 670 680 690 700 710 pF1KB3 IHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVA 520 530 540 550 560 570 720 730 740 750 760 770 pF1KB3 RREVREDARRRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RREVREDARRRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDH 580 590 600 610 620 630 pF1KB3 SDTRKETG :::::::: XP_016 SDTRKETG 640 >>XP_016880571 (OMIM: 607570) PREDICTED: probable ATP-de (640 aa) initn: 4292 init1: 4292 opt: 4292 Z-score: 5198.1 bits: 972.3 E(85289): 0 Smith-Waterman score: 4292; 99.8% identity (100.0% similar) in 638 aa overlap (142-779:3-640) 120 130 140 150 160 170 pF1KB3 ISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVII .::::::::::::::::::::::::::::: XP_016 MKQETAIKYMTDGCLLKHILGDPNLTKFSVII 10 20 30 180 190 200 210 220 230 pF1KB3 LDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIP 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB3 GRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCEL 100 110 120 130 140 150 300 310 320 330 340 350 pF1KB3 LFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATS 160 170 180 190 200 210 360 370 380 390 400 410 pF1KB3 LTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSK 220 230 240 250 260 270 420 430 440 450 460 470 pF1KB3 DFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCD 280 290 300 310 320 330 480 490 500 510 520 530 pF1KB3 AIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPE 340 350 360 370 380 390 540 550 560 570 580 590 pF1KB3 YQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEA 400 410 420 430 440 450 600 610 620 630 640 650 pF1KB3 QLRELIRKLKQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLRELIRKLKQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVH 460 470 480 490 500 510 660 670 680 690 700 710 pF1KB3 IHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVA 520 530 540 550 560 570 720 730 740 750 760 770 pF1KB3 RREVREDARRRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RREVREDARRRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDH 580 590 600 610 620 630 pF1KB3 SDTRKETG :::::::: XP_016 SDTRKETG 640 >>XP_006722146 (OMIM: 607570) PREDICTED: probable ATP-de (752 aa) initn: 2961 init1: 2961 opt: 2961 Z-score: 3583.5 bits: 673.8 E(85289): 7.3e-193 Smith-Waterman score: 4971; 96.5% identity (96.5% similar) in 779 aa overlap (1-779:1-752) 10 20 30 40 50 60 pF1KB3 MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 HVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVT :::::::::::::::::::::::::::: ::::: XP_006 HVIPEIKRTSLTSVVLTLKCLAIHDVIR---------------------------SGHVT 430 440 450 490 500 510 520 530 540 pF1KB3 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB3 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB3 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHE 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB3 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR 640 650 660 670 680 690 730 740 750 760 770 pF1KB3 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG 700 710 720 730 740 750 >>XP_011523555 (OMIM: 607570) PREDICTED: probable ATP-de (718 aa) initn: 2549 init1: 2549 opt: 2549 Z-score: 3084.3 bits: 581.4 E(85289): 4.7e-165 Smith-Waterman score: 4680; 92.2% identity (92.2% similar) in 779 aa overlap (1-779:1-718) 10 20 30 40 50 60 pF1KB3 MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSRFPAVAGRAPRRQEEGERSRDLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPD ::::::::::::::::::::::::::: XP_011 VDGGFVKQLNHNPRLGLDILEVVPISK--------------------------------- 370 380 430 440 450 460 470 480 pF1KB3 HVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVT :::::::::::::::::::::::::::::::: XP_011 ----------------------------FPYLDPPNERLILEALKQLYQCDAIDRSGHVT 390 400 410 490 500 510 520 530 540 pF1KB3 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRH 420 430 440 450 460 470 550 560 570 580 590 600 pF1KB3 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL 480 490 500 510 520 530 610 620 630 640 650 660 pF1KB3 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQQSDFPKETFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHE 540 550 560 570 580 590 670 680 690 700 710 720 pF1KB3 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDAR 600 610 620 630 640 650 730 740 750 760 770 pF1KB3 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRWTNKENVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG 660 670 680 690 700 710 >>XP_016880570 (OMIM: 607570) PREDICTED: probable ATP-de (653 aa) initn: 2306 init1: 2306 opt: 2306 Z-score: 2790.2 bits: 526.8 E(85289): 1.1e-148 Smith-Waterman score: 4316; 96.0% identity (96.0% similar) in 680 aa overlap (100-779:1-653) 70 80 90 100 110 120 pF1KB3 SFLIVTGNTGSGKTTQLPKYLYEAGFSQHGMIGVTQPRKVAAISVAQRVAEEMKCTLGSK :::::::::::::::::::::::::::::: XP_016 MIGVTQPRKVAAISVAQRVAEEMKCTLGSK 10 20 30 130 140 150 160 170 180 pF1KB3 VGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLL 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB3 KKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRD 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB3 RENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTT 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB3 LDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQL 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB3 NHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRT 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB3 SLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEF ::::::::::::::::::: :::::::::::::: XP_016 SLTSVVLTLKCLAIHDVIR---------------------------SGHVTRLGLSMVEF 340 350 360 490 500 510 520 530 540 pF1KB3 PLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGG 370 380 390 400 410 420 550 560 570 580 590 600 pF1KB3 FNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKLKQQSDFPKE 430 440 450 460 470 480 610 620 630 640 650 660 pF1KB3 TFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFEGPKHEVLRRCLCAGYFKNVARRSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEWII 490 500 510 520 530 540 670 680 690 700 710 720 pF1KB3 FHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDARRRWTNKENV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDARRRWTNKENV 550 560 570 580 590 600 730 740 750 760 770 pF1KB3 KQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG 610 620 630 640 650 >>NP_001349 (OMIM: 603403) pre-mRNA-splicing factor ATP- (795 aa) initn: 1343 init1: 586 opt: 1078 Z-score: 1300.2 bits: 251.4 E(85289): 1.1e-65 Smith-Waterman score: 1568; 40.5% identity (69.3% similar) in 684 aa overlap (53-721:137-782) 30 40 50 60 70 80 pF1KB3 DLQEERLSAVCIADREEKGCTSQEGGTTPTFPIQKQRKKIIQA-VRDNSFLIVTGNTGSG .:. . . .. . :: .::..: :.:::: NP_001 GHTSLPQCINPFTNLPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLV-GETGSG 110 120 130 140 150 160 90 100 110 120 130 pF1KB3 KTTQLPKYLYEAGFSQHGM---IGVTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDD ::::.:.. : : : .. ::::.:::.:::::::.:: ::..:::..::.: NP_001 KTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFED 170 180 190 200 210 220 140 150 160 170 180 190 pF1KB3 CSSKETAIKYMTDGCLLKHILGDPNLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSP ::: .: .:::::: ::.. ..:: : ...::::::::::::.::::.:.::.. ...: NP_001 CSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSD 230 240 250 260 270 280 200 210 220 230 240 250 pF1KB3 NRKEHLKVVVMSATMELAKLSAFFGNCPIFDIPGRLYPVREKFCNLIGPRDRENTAYIQA :::.:::::.. .:.. .: :::.. :::: .:: : : . :: :..: NP_001 -----LKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPV-EIFYTPEPERD-----YLEA 290 300 310 320 330 260 270 280 290 300 310 pF1KB3 IVKVTMDIHL-NEMAGDILVFLTGQFEIEKSCELLFQMAESVDYDYDVQDTTLDGLLILP ......::. .: ::.:.::::: ::...:. .. . :: :. . : . :.: NP_001 AIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACK---RIKREVD---DLGPEVGD-IKIIP 340 350 360 370 380 320 330 340 350 360 370 pF1KB3 CYGSMTTDQQRRIFLPPPP----GI--RKCVISTNISATSLTIDGIRYVVDGGFVKQLNH :... .::.::: :::: : :: :.::::. :::::::. .:.: ::.:: . NP_001 LYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVY 390 400 410 420 430 440 380 390 400 410 420 430 pF1KB3 NPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSL :::. .. : :. :::. : ::.:::::: :::::.:.. .. : :.. ::: :..: NP_001 NPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNL 450 460 470 480 490 500 440 450 460 470 480 490 pF1KB3 TSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQCDAIDRSGHVTRLGLSMVEFPL :::: :: :.: :...: ..::: . ...::. : :.. .: .:.:: :.:::: NP_001 GSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPL 510 520 530 540 550 560 500 510 520 530 540 550 pF1KB3 PPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRPVDPEYQKEAEQRHRELAAKAGGFN :.:. :: . . .: . .: :.::::: . :.::. : .: :.. . ..: : NP_001 DPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPT--EAKKAADEAKMRFAHIDG--- 570 580 590 600 610 620 560 570 580 590 600 pF1KB3 DFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFRVEAQLRELIRKL---KQQSDFPK : :: ... :.. ..:: ..:..: :.:: :. :: ... .. ....:: . NP_001 DHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTS 630 640 650 660 670 680 610 620 630 640 650 660 pF1KB3 ETFEGPKHEVLRRCLCAGYFKNVAR-RSVGRTFCTMDGRGSPVHIHPSSALHEQETKLEW . . . .:. : .::: .::. . .:. . . :.. :..:::..: . : :: NP_001 RDY----YINIRKALVTGYFMQVAHLERTGHYLTVKDNQ--VVQLHPSTVL---DHKPEW 690 700 710 720 730 670 680 690 700 710 720 pF1KB3 IIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHEFNAHDLSSVARREVREDARRRWTNKE ....: ..::: : : :. ::. . :. . :.:. . :.... : NP_001 VLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYY-----DMSNFPQCEAKRQLDRIIAKLQ 740 750 760 770 780 730 740 750 760 770 pF1KB3 NVKQLKDGISKDVLKKMQRRNDDKSISDARARFLERKQQRTQDHSDTRKETG NP_001 SKEYSQY 790 779 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:31:12 2016 done: Thu Nov 3 20:31:13 2016 Total Scan time: 12.430 Total Display time: 0.250 Function used was FASTA [36.3.4 Apr, 2011]