FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3020, 641 aa 1>>>pF1KB3020 641 - 641 aa - 641 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8018+/-0.000452; mu= 4.6860+/- 0.028 mean_var=368.4079+/-80.535, 0's: 0 Z-trim(120.7): 1648 B-trim: 0 in 0/51 Lambda= 0.066821 statistics sampled from 34270 (36255) to 34270 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.425), width: 16 Scan time: 12.190 The best scores are: opt bits E(85289) NP_114439 (OMIM: 605165) POZ-, AT hook-, and zinc ( 641) 4427 441.5 4.2e-123 NP_114441 (OMIM: 605165) POZ-, AT hook-, and zinc ( 537) 3469 349.1 2.4e-95 NP_055138 (OMIM: 605165) POZ-, AT hook-, and zinc ( 687) 3469 349.2 2.8e-95 NP_114440 (OMIM: 605165) POZ-, AT hook-, and zinc ( 537) 3050 308.7 3.5e-83 NP_001263204 (OMIM: 600999) myc-associated zinc fi ( 454) 874 98.8 4.4e-20 NP_002374 (OMIM: 600999) myc-associated zinc finge ( 477) 874 98.9 4.5e-20 XP_006721110 (OMIM: 600999) PREDICTED: myc-associa ( 470) 850 96.5 2.2e-19 NP_001036004 (OMIM: 600999) myc-associated zinc fi ( 493) 850 96.6 2.3e-19 NP_001317322 (OMIM: 606747) vascular endothelial z ( 512) 797 91.5 8.1e-18 XP_016880507 (OMIM: 606747) PREDICTED: vascular en ( 512) 797 91.5 8.1e-18 NP_009077 (OMIM: 606747) vascular endothelial zinc ( 521) 797 91.5 8.2e-18 XP_005257701 (OMIM: 606747) PREDICTED: vascular en ( 518) 775 89.4 3.6e-17 XP_005257700 (OMIM: 606747) PREDICTED: vascular en ( 527) 775 89.4 3.6e-17 NP_001243384 (OMIM: 607646) zinc finger and BTB do ( 539) 596 72.1 5.7e-12 XP_006711420 (OMIM: 607646) PREDICTED: zinc finger ( 539) 596 72.1 5.7e-12 XP_006711419 (OMIM: 607646) PREDICTED: zinc finger ( 539) 596 72.1 5.7e-12 XP_011507901 (OMIM: 607646) PREDICTED: zinc finger ( 539) 596 72.1 5.7e-12 XP_006711422 (OMIM: 607646) PREDICTED: zinc finger ( 539) 596 72.1 5.7e-12 XP_006711412 (OMIM: 607646) PREDICTED: zinc finger ( 539) 596 72.1 5.7e-12 XP_006711421 (OMIM: 607646) PREDICTED: zinc finger ( 539) 596 72.1 5.7e-12 XP_006711417 (OMIM: 607646) PREDICTED: zinc finger ( 539) 596 72.1 5.7e-12 XP_006711416 (OMIM: 607646) PREDICTED: zinc finger ( 539) 596 72.1 5.7e-12 XP_011507900 (OMIM: 607646) PREDICTED: zinc finger ( 573) 596 72.2 5.9e-12 NP_001239335 (OMIM: 607646) zinc finger and BTB do ( 573) 596 72.2 5.9e-12 XP_016856888 (OMIM: 607646) PREDICTED: zinc finger ( 630) 596 72.2 6.2e-12 XP_006721111 (OMIM: 600999) PREDICTED: myc-associa ( 401) 587 71.1 8.7e-12 NP_001252529 (OMIM: 601856) zinc finger protein 21 ( 503) 506 63.4 2.2e-09 NP_001252528 (OMIM: 601856) zinc finger protein 21 ( 555) 506 63.5 2.4e-09 NP_942152 (OMIM: 601856) zinc finger protein 211 i ( 564) 506 63.5 2.4e-09 NP_006376 (OMIM: 601856) zinc finger protein 211 i ( 577) 506 63.5 2.4e-09 NP_001252527 (OMIM: 601856) zinc finger protein 21 ( 616) 506 63.5 2.5e-09 NP_001309235 (OMIM: 601856) zinc finger protein 21 ( 627) 506 63.5 2.5e-09 NP_001252526 (OMIM: 601856) zinc finger protein 21 ( 629) 506 63.5 2.6e-09 XP_011540503 (OMIM: 611703) PREDICTED: zinc finger ( 452) 479 60.7 1.3e-08 NP_001070663 (OMIM: 611703) zinc finger protein 43 ( 470) 479 60.8 1.3e-08 NP_085137 (OMIM: 611703) zinc finger protein 436 [ ( 470) 479 60.8 1.3e-08 NP_001295198 (OMIM: 194628) zinc finger protein 12 ( 390) 471 59.9 2e-08 NP_001008727 (OMIM: 194628) zinc finger protein 12 ( 390) 471 59.9 2e-08 XP_016882728 (OMIM: 194628) PREDICTED: zinc finger ( 390) 471 59.9 2e-08 XP_016882440 (OMIM: 194558) PREDICTED: zinc finger ( 516) 472 60.2 2.2e-08 NP_001264878 (OMIM: 194558) zinc finger protein 83 ( 516) 472 60.2 2.2e-08 NP_060770 (OMIM: 194558) zinc finger protein 83 [H ( 516) 472 60.2 2.2e-08 NP_001099022 (OMIM: 194558) zinc finger protein 83 ( 516) 472 60.2 2.2e-08 NP_001264881 (OMIM: 194558) zinc finger protein 83 ( 516) 472 60.2 2.2e-08 NP_001264877 (OMIM: 194558) zinc finger protein 83 ( 516) 472 60.2 2.2e-08 NP_001264876 (OMIM: 194558) zinc finger protein 83 ( 516) 472 60.2 2.2e-08 NP_001264880 (OMIM: 194558) zinc finger protein 83 ( 516) 472 60.2 2.2e-08 NP_001099021 (OMIM: 194558) zinc finger protein 83 ( 516) 472 60.2 2.2e-08 NP_001264875 (OMIM: 194558) zinc finger protein 83 ( 516) 472 60.2 2.2e-08 NP_001099020 (OMIM: 194558) zinc finger protein 83 ( 516) 472 60.2 2.2e-08 >>NP_114439 (OMIM: 605165) POZ-, AT hook-, and zinc fing (641 aa) initn: 4427 init1: 4427 opt: 4427 Z-score: 2331.0 bits: 441.5 E(85289): 4.2e-123 Smith-Waterman score: 4427; 99.8% identity (99.8% similar) in 641 aa overlap (1-641:1-641) 10 20 30 40 50 60 pF1KB3 MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 ACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 AYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 SDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGTLPCGLCGKV :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_114 PLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 FTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 FTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEIC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 YMADHLKKHSEGPSNFCSICNREGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSANGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 YMADHLKKHSEGPSNFCSICNREGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSANGSF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 SCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 SCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSP 550 560 570 580 590 600 610 620 630 640 pF1KB3 FSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK ::::::::::::::::::::::::::::::::::::::::: NP_114 FSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK 610 620 630 640 >>NP_114441 (OMIM: 605165) POZ-, AT hook-, and zinc fing (537 aa) initn: 3466 init1: 3466 opt: 3469 Z-score: 1832.7 bits: 349.1 E(85289): 2.4e-95 Smith-Waterman score: 3469; 95.5% identity (96.6% similar) in 532 aa overlap (1-532:1-530) 10 20 30 40 50 60 pF1KB3 MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 ACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 AYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 SDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGTLPCGLCGKV :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_114 PLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 FTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 FTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEIC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 YMADHLKKHSEGPSNFCSICNREGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSANGSF :::::::::::::::::::::: : . : : ..: .: . . :: NP_114 YMADHLKKHSEGPSNFCSICNR-GLQAPGAHP-EWGSSVPLRQDLWQQRRPEMLTSGSD 490 500 510 520 530 550 560 570 580 590 600 pF1KB3 SCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSP >>NP_055138 (OMIM: 605165) POZ-, AT hook-, and zinc fing (687 aa) initn: 3466 init1: 3466 opt: 3469 Z-score: 1831.6 bits: 349.2 E(85289): 2.8e-95 Smith-Waterman score: 4219; 93.0% identity (93.0% similar) in 673 aa overlap (1-627:1-673) 10 20 30 40 50 60 pF1KB3 MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGTLPCGLCGKV :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_055 PLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 FTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEIC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAA 430 440 450 460 470 480 490 500 pF1KB3 YMADHLKKHSEGPSNFCSICNR-------------------------------------- :::::::::::::::::::::: NP_055 YMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPILNGGAAFH 490 500 510 520 530 540 510 520 530 540 550 pF1KB3 --------EGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSANGSFSCDMAVPKNKMESD :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CARTYGNKEGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSANGSFSCDMAVPKNKMESD 550 560 570 580 590 600 560 570 580 590 600 610 pF1KB3 GEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFG 610 620 630 640 650 660 620 630 640 pF1KB3 FQIVQSAFASSLVDPEVDQQPMGPEGK ::::::::::::: NP_055 FQIVQSAFASSLVDPEVDQQPMGPEGK 670 680 >>NP_114440 (OMIM: 605165) POZ-, AT hook-, and zinc fing (537 aa) initn: 3050 init1: 3050 opt: 3050 Z-score: 1614.4 bits: 308.7 E(85289): 3.5e-83 Smith-Waterman score: 3050; 99.8% identity (99.8% similar) in 445 aa overlap (1-445:1-445) 10 20 30 40 50 60 pF1KB3 MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 ACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 AYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 AYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 SDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGTLPCGLCGKV :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::: NP_114 PLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 FTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 FTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEIC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 GFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAA ::::::::::::::::::::::::: NP_114 GFSRPDHLNGHIKQVHTSERPHKCQVWVGSSSGLPPLEPLPSDLPSWDFAQPALWRSSHS 430 440 450 460 470 480 >>NP_001263204 (OMIM: 600999) myc-associated zinc finger (454 aa) initn: 983 init1: 838 opt: 874 Z-score: 481.5 bits: 98.8 E(85289): 4.4e-20 Smith-Waterman score: 927; 40.7% identity (62.3% similar) in 408 aa overlap (177-547:46-443) 150 160 170 180 190 200 pF1KB3 SVIEICQEVIKQSNVQILVPPARADIMLFRPPGT--SDLGFPLDMTNGAALAANSNGIAG :: : . . ::.. .::: ... :. NP_001 QNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAA 20 30 40 50 60 70 210 220 230 240 250 260 pF1KB3 SMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPSVASSAPPLTGK . :: .:.: : :. : .. . : : : : ...: .: .::: .. NP_001 AAAAAAAAAAVAAAPPAPAAASTVDTAALKQPP-APPPPPPPVSAP---AAEAAPPASAA 80 90 100 110 120 130 270 280 290 300 310 pF1KB3 RGRGRPRKANL--LDSMFGSPGG------LREAGTLPCGLCGKVFTDANRLRQHEAQH-G . : . ... .: . . : :.::.: : .. ::.::: : : NP_001 TIAAAAATAVVAPTSTVAVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTG 140 150 160 170 180 190 320 330 340 350 pF1KB3 VTSLQL--GYIDLP---P------PRLGENGLPISEDPDG--------------PRKRSR . . .. : . .: : :.:. : .: : . .: NP_001 AKAGRVPSGAMKMPTMVPLSLLSVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGKR 200 210 220 230 240 250 360 370 380 390 400 410 pF1KB3 TRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVG ::. :::.::: ::::::::::::::: ::::.:::: :::::::::::::::::.: NP_001 IRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVH 260 270 280 290 300 310 420 430 440 450 460 470 pF1KB3 KPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPC ::: :. :::.::::::::.:..:::..::: ::. :.:.:::.::::.: . ::.:::: NP_001 KPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKVPC 320 330 340 350 360 370 480 490 500 510 520 pF1KB3 QVCGKYLRAAYMADHLKKHSEGPSNFCSICNR-EGQKCSHQDPIESSDSYGDLSDASDLK .::::.: .::..::.: ::.:: . : .::. :. : :. .. . . . :. . NP_001 HVCGKMLSSAYISDHMKVHSQGPHHVCELCNKGTGEVC----PMAAAAAAAAAAAAAAVA 380 390 400 410 420 530 540 550 560 570 580 pF1KB3 TPEKQSANGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGP .: .: ::.: .:: NP_001 APP--TAVGSLSGAEGVPVSSQPLPSQPW 430 440 450 >>NP_002374 (OMIM: 600999) myc-associated zinc finger pr (477 aa) initn: 983 init1: 838 opt: 874 Z-score: 481.3 bits: 98.9 E(85289): 4.5e-20 Smith-Waterman score: 927; 40.7% identity (62.3% similar) in 408 aa overlap (177-547:69-466) 150 160 170 180 190 200 pF1KB3 SVIEICQEVIKQSNVQILVPPARADIMLFRPPGT--SDLGFPLDMTNGAALAANSNGIAG :: : . . ::.. .::: ... :. NP_002 QNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAA 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB3 SMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPSVASSAPPLTGK . :: .:.: : :. : .. . : : : : ...: .: .::: .. NP_002 AAAAAAAAAAVAAAPPAPAAASTVDTAALKQPP-APPPPPPPVSAP---AAEAAPPASAA 100 110 120 130 140 150 270 280 290 300 310 pF1KB3 RGRGRPRKANL--LDSMFGSPGG------LREAGTLPCGLCGKVFTDANRLRQHEAQH-G . : . ... .: . . : :.::.: : .. ::.::: : : NP_002 TIAAAAATAVVAPTSTVAVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTG 160 170 180 190 200 210 320 330 340 350 pF1KB3 VTSLQL--GYIDLP---P------PRLGENGLPISEDPDG--------------PRKRSR . . .. : . .: : :.:. : .: : . .: NP_002 AKAGRVPSGAMKMPTMVPLSLLSVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGKR 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB3 TRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVG ::. :::.::: ::::::::::::::: ::::.:::: :::::::::::::::::.: NP_002 IRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVH 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB3 KPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPC ::: :. :::.::::::::.:..:::..::: ::. :.:.:::.::::.: . ::.:::: NP_002 KPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKVPC 340 350 360 370 380 390 480 490 500 510 520 pF1KB3 QVCGKYLRAAYMADHLKKHSEGPSNFCSICNR-EGQKCSHQDPIESSDSYGDLSDASDLK .::::.: .::..::.: ::.:: . : .::. :. : :. .. . . . :. . NP_002 HVCGKMLSSAYISDHMKVHSQGPHHVCELCNKGTGEVC----PMAAAAAAAAAAAAAAVA 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB3 TPEKQSANGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGP .: .: ::.: .:: NP_002 APP--TAVGSLSGAEGVPVSSQPLPSQPW 460 470 >>XP_006721110 (OMIM: 600999) PREDICTED: myc-associated (470 aa) initn: 983 init1: 838 opt: 850 Z-score: 468.9 bits: 96.5 E(85289): 2.2e-19 Smith-Waterman score: 905; 38.7% identity (59.2% similar) in 434 aa overlap (177-564:46-470) 150 160 170 180 190 200 pF1KB3 SVIEICQEVIKQSNVQILVPPARADIMLFRPPGT--SDLGFPLDMTNGAALAANSNGIAG :: : . . ::.. .::: ... :. XP_006 QNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAA 20 30 40 50 60 70 210 220 230 240 250 260 pF1KB3 SMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPSVASSAPPLTGK . :: .:.: : :. : .. . : : : : ...: .: .::: .. XP_006 AAAAAAAAAAVAAAPPAPAAASTVDTAALKQPP-APPPPPPPVSAP---AAEAAPPASAA 80 90 100 110 120 130 270 280 290 300 310 pF1KB3 RGRGRPRKANL--LDSMFGSPGG------LREAGTLPCGLCGKVFTDANRLRQHEAQH-G . : . ... .: . . : :.::.: : .. ::.::: : : XP_006 TIAAAAATAVVAPTSTVAVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTG 140 150 160 170 180 190 320 330 340 350 pF1KB3 VTSLQL--GYIDLP---P------PRLGENGLPISEDPDG--------------PRKRSR . . .. : . .: : :.:. : .: : . .: XP_006 AKAGRVPSGAMKMPTMVPLSLLSVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGKR 200 210 220 230 240 250 360 370 380 390 400 410 pF1KB3 TRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVG ::. :::.::: ::::::::::::::: ::::.:::: :::::::::::::::::.: XP_006 IRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVH 260 270 280 290 300 310 420 430 440 450 460 470 pF1KB3 KPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPC ::: :. :::.::::::::.:..:::..::: ::. :.:.:::.::::.: . ::.:::: XP_006 KPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKVPC 320 330 340 350 360 370 480 490 500 510 520 pF1KB3 QVCGKYLRAAYMADHLKKHSEGPSNFCSICNREGQKCSHQDPIESSDSYGDLSDASD--- .::::.: .::..::.: ::.:: . : .::. : . :.. ..: . .: XP_006 HVCGKMLSSAYISDHMKVHSQGPHHVCELCNK-GFTTAAYLRIHAVKDHGLQAPRADRIL 380 390 400 410 420 430 530 540 550 560 570 580 pF1KB3 -------LKTPEKQSANGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQK ::: . ... . :.: :. : : : XP_006 CKLCSVHCKTPAQLAGHMQTHLGGAAP----PVPGDAPQPQPTC 440 450 460 470 590 600 610 620 630 640 pF1KB3 VHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEG >>NP_001036004 (OMIM: 600999) myc-associated zinc finger (493 aa) initn: 983 init1: 838 opt: 850 Z-score: 468.6 bits: 96.6 E(85289): 2.3e-19 Smith-Waterman score: 905; 38.7% identity (59.2% similar) in 434 aa overlap (177-564:69-493) 150 160 170 180 190 200 pF1KB3 SVIEICQEVIKQSNVQILVPPARADIMLFRPPGT--SDLGFPLDMTNGAALAANSNGIAG :: : . . ::.. .::: ... :. NP_001 QNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAA 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB3 SMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPSVASSAPPLTGK . :: .:.: : :. : .. . : : : : ...: .: .::: .. NP_001 AAAAAAAAAAVAAAPPAPAAASTVDTAALKQPP-APPPPPPPVSAP---AAEAAPPASAA 100 110 120 130 140 150 270 280 290 300 310 pF1KB3 RGRGRPRKANL--LDSMFGSPGG------LREAGTLPCGLCGKVFTDANRLRQHEAQH-G . : . ... .: . . : :.::.: : .. ::.::: : : NP_001 TIAAAAATAVVAPTSTVAVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTG 160 170 180 190 200 210 320 330 340 350 pF1KB3 VTSLQL--GYIDLP---P------PRLGENGLPISEDPDG--------------PRKRSR . . .. : . .: : :.:. : .: : . .: NP_001 AKAGRVPSGAMKMPTMVPLSLLSVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGKR 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB3 TRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVG ::. :::.::: ::::::::::::::: ::::.:::: :::::::::::::::::.: NP_001 IRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVH 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB3 KPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPC ::: :. :::.::::::::.:..:::..::: ::. :.:.:::.::::.: . ::.:::: NP_001 KPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKVPC 340 350 360 370 380 390 480 490 500 510 520 pF1KB3 QVCGKYLRAAYMADHLKKHSEGPSNFCSICNREGQKCSHQDPIESSDSYGDLSDASD--- .::::.: .::..::.: ::.:: . : .::. : . :.. ..: . .: NP_001 HVCGKMLSSAYISDHMKVHSQGPHHVCELCNK-GFTTAAYLRIHAVKDHGLQAPRADRIL 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB3 -------LKTPEKQSANGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQK ::: . ... . :.: :. : : : NP_001 CKLCSVHCKTPAQLAGHMQTHLGGAAP----PVPGDAPQPQPTC 460 470 480 490 590 600 610 620 630 640 pF1KB3 VHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEG >>NP_001317322 (OMIM: 606747) vascular endothelial zinc (512 aa) initn: 934 init1: 754 opt: 797 Z-score: 440.9 bits: 91.5 E(85289): 8.1e-18 Smith-Waterman score: 797; 55.9% identity (80.1% similar) in 186 aa overlap (327-511:139-322) 300 310 320 330 340 350 pF1KB3 CGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVA : . ...:.... : : ..:. : NP_001 TIAGDSSRTSLVSTIAGILSTVTTSSSGTNPSSSASTTAMPVTQSVKKPSK--PVKKNHA 110 120 130 140 150 160 360 370 380 390 400 410 pF1KB3 CEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQ ::.::: ::::::::::::::: :::. ::.:. ::::::::.::::::.:.. ::: :. NP_001 CEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCS 170 180 190 200 210 220 420 430 440 450 460 470 pF1KB3 SCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKY :::::::::::. :.:.::..::: :::::.:.:::.::::.:.. :: :: :..::: NP_001 VCGKGFSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKDRLRTHMVRHEGKVSCNICGKL 230 240 250 260 270 280 480 490 500 510 520 530 pF1KB3 LRAAYMADHLKKHSEGPSNFCSICNREGQK-CSHQDPIESSDSYGDLSDASDLKTPEKQS : :::...::: :... : :. :.. .: : .. NP_001 LSAAYITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQQQQQH 290 300 310 320 330 340 540 550 560 570 580 590 pF1KB3 ANGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGP NP_001 VTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFSITSSVSSGTMSNP 350 360 370 380 390 400 >>XP_016880507 (OMIM: 606747) PREDICTED: vascular endoth (512 aa) initn: 934 init1: 754 opt: 797 Z-score: 440.9 bits: 91.5 E(85289): 8.1e-18 Smith-Waterman score: 797; 55.9% identity (80.1% similar) in 186 aa overlap (327-511:139-322) 300 310 320 330 340 350 pF1KB3 CGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVA : . ...:.... : : ..:. : XP_016 TIAGDSSRTSLVSTIAGILSTVTTSSSGTNPSSSASTTAMPVTQSVKKPSK--PVKKNHA 110 120 130 140 150 160 360 370 380 390 400 410 pF1KB3 CEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQ ::.::: ::::::::::::::: :::. ::.:. ::::::::.::::::.:.. ::: :. XP_016 CEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCS 170 180 190 200 210 220 420 430 440 450 460 470 pF1KB3 SCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKY :::::::::::. :.:.::..::: :::::.:.:::.::::.:.. :: :: :..::: XP_016 VCGKGFSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKDRLRTHMVRHEGKVSCNICGKL 230 240 250 260 270 280 480 490 500 510 520 530 pF1KB3 LRAAYMADHLKKHSEGPSNFCSICNREGQK-CSHQDPIESSDSYGDLSDASDLKTPEKQS : :::...::: :... : :. :.. .: : .. XP_016 LSAAYITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQQQQQH 290 300 310 320 330 340 540 550 560 570 580 590 pF1KB3 ANGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGP XP_016 VTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFSITSSVSSGTMSNP 350 360 370 380 390 400 641 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:31:51 2016 done: Thu Nov 3 20:31:53 2016 Total Scan time: 12.190 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]