FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3027, 1214 aa 1>>>pF1KB3027 1214 - 1214 aa - 1214 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.3451+/-0.000406; mu= -5.7958+/- 0.025 mean_var=337.3835+/-69.200, 0's: 0 Z-trim(121.9): 115 B-trim: 941 in 2/58 Lambda= 0.069825 statistics sampled from 38990 (39133) to 38990 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.459), width: 16 Scan time: 18.310 The best scores are: opt bits E(85289) NP_004625 (OMIM: 602410) peregrin isoform 2 [Homo (1214) 8307 851.7 0 NP_001305979 (OMIM: 602410) peregrin isoform 4 [Ho (1213) 8290 850.0 0 NP_001003694 (OMIM: 602410) peregrin isoform 1 [Ho (1220) 8285 849.5 0 XP_005265507 (OMIM: 602410) PREDICTED: peregrin is (1219) 8268 847.8 0 XP_011532403 (OMIM: 602410) PREDICTED: peregrin is (1248) 7262 746.5 2.5e-214 XP_011532404 (OMIM: 602410) PREDICTED: peregrin is (1248) 7262 746.5 2.5e-214 XP_005265506 (OMIM: 602410) PREDICTED: peregrin is (1247) 7245 744.8 8.2e-214 NP_001305978 (OMIM: 602410) peregrin isoform 3 [Ho (1119) 6004 619.7 3.2e-176 XP_005265509 (OMIM: 602410) PREDICTED: peregrin is (1125) 5985 617.8 1.2e-175 NP_001291737 (OMIM: 604589) bromodomain-containing (1189) 3061 323.3 6e-87 XP_016884206 (OMIM: 604589) PREDICTED: bromodomain (1189) 3061 323.3 6e-87 XP_016884204 (OMIM: 604589) PREDICTED: bromodomain (1189) 3061 323.3 6e-87 XP_016884205 (OMIM: 604589) PREDICTED: bromodomain (1189) 3061 323.3 6e-87 XP_016884209 (OMIM: 604589) PREDICTED: bromodomain ( 955) 3057 322.8 6.7e-87 XP_016884208 (OMIM: 604589) PREDICTED: bromodomain ( 958) 3057 322.8 6.7e-87 XP_016884210 (OMIM: 604589) PREDICTED: bromodomain ( 941) 3040 321.1 2.2e-86 NP_001291738 (OMIM: 604589) bromodomain-containing (1058) 3027 319.8 5.9e-86 XP_016884207 (OMIM: 604589) PREDICTED: bromodomain (1023) 3024 319.5 7.1e-86 XP_016884203 (OMIM: 604589) PREDICTED: bromodomain (1187) 2450 261.7 2e-68 XP_016866231 (OMIM: 616856) PREDICTED: bromodomain (1088) 1915 207.8 3.2e-52 XP_011512793 (OMIM: 616856) PREDICTED: bromodomain (1131) 1915 207.8 3.3e-52 XP_011512792 (OMIM: 616856) PREDICTED: bromodomain (1144) 1915 207.8 3.3e-52 NP_056510 (OMIM: 616856) bromodomain and PHD finge (1205) 1915 207.8 3.4e-52 XP_011512791 (OMIM: 616856) PREDICTED: bromodomain (1205) 1915 207.8 3.4e-52 XP_005249068 (OMIM: 616856) PREDICTED: bromodomain (1205) 1915 207.8 3.4e-52 XP_005249067 (OMIM: 616856) PREDICTED: bromodomain (1205) 1915 207.8 3.4e-52 XP_011512794 (OMIM: 616856) PREDICTED: bromodomain ( 832) 1890 205.2 1.5e-51 XP_011528375 (OMIM: 604589) PREDICTED: bromodomain ( 784) 1224 138.1 2.2e-31 XP_016884211 (OMIM: 604589) PREDICTED: bromodomain ( 802) 1224 138.1 2.2e-31 XP_016884212 (OMIM: 604589) PREDICTED: bromodomain ( 643) 1217 137.3 3.1e-31 XP_016866232 (OMIM: 616856) PREDICTED: bromodomain ( 572) 705 85.7 9.4e-16 NP_055550 (OMIM: 300618) protein Jade-3 [Homo sapi ( 823) 699 85.2 1.9e-15 NP_001070913 (OMIM: 300618) protein Jade-3 [Homo s ( 823) 699 85.2 1.9e-15 XP_016864116 (OMIM: 610514) PREDICTED: protein Jad ( 529) 664 81.6 1.5e-14 XP_016864115 (OMIM: 610514) PREDICTED: protein Jad ( 529) 664 81.6 1.5e-14 NP_001274370 (OMIM: 610514) protein Jade-1 isoform ( 509) 662 81.3 1.7e-14 NP_079176 (OMIM: 610514) protein Jade-1 isoform 2 ( 509) 662 81.3 1.7e-14 NP_001274366 (OMIM: 610514) protein Jade-1 isoform ( 830) 665 81.8 2.1e-14 NP_001274372 (OMIM: 610514) protein Jade-1 isoform ( 842) 660 81.3 2.9e-14 XP_005263289 (OMIM: 610514) PREDICTED: protein Jad ( 842) 660 81.3 2.9e-14 NP_001274369 (OMIM: 610514) protein Jade-1 isoform ( 842) 660 81.3 2.9e-14 NP_001274371 (OMIM: 610514) protein Jade-1 isoform ( 842) 660 81.3 2.9e-14 NP_955352 (OMIM: 610514) protein Jade-1 isoform 1 ( 842) 660 81.3 2.9e-14 NP_001274368 (OMIM: 610514) protein Jade-1 isoform ( 842) 660 81.3 2.9e-14 NP_056103 (OMIM: 610515) protein Jade-2 isoform 3 ( 790) 649 80.2 6e-14 NP_001276913 (OMIM: 610515) protein Jade-2 isoform ( 791) 649 80.2 6e-14 XP_016864771 (OMIM: 610515) PREDICTED: protein Jad ( 833) 649 80.2 6.3e-14 XP_011541593 (OMIM: 610515) PREDICTED: protein Jad ( 834) 649 80.2 6.3e-14 XP_005272002 (OMIM: 610515) PREDICTED: protein Jad ( 834) 649 80.2 6.3e-14 XP_005272003 (OMIM: 610515) PREDICTED: protein Jad ( 834) 649 80.2 6.3e-14 >>NP_004625 (OMIM: 602410) peregrin isoform 2 [Homo sapi (1214 aa) initn: 8307 init1: 8307 opt: 8307 Z-score: 4537.9 bits: 851.7 E(85289): 0 Smith-Waterman score: 8307; 100.0% identity (100.0% similar) in 1214 aa overlap (1-1214:1-1214) 10 20 30 40 50 60 pF1KB3 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDED 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 SPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEARE 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB3 HLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRS 1150 1160 1170 1180 1190 1200 1210 pF1KB3 KVQGEQSSETSDSD :::::::::::::: NP_004 KVQGEQSSETSDSD 1210 >>NP_001305979 (OMIM: 602410) peregrin isoform 4 [Homo s (1213 aa) initn: 5421 init1: 5309 opt: 8290 Z-score: 4528.7 bits: 850.0 E(85289): 0 Smith-Waterman score: 8290; 99.9% identity (99.9% similar) in 1214 aa overlap (1-1214:1-1213) 10 20 30 40 50 60 pF1KB3 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: NP_001 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA-EEERLVLLENQKHL 730 740 750 760 770 790 800 810 820 830 840 pF1KB3 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB3 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK 840 850 860 870 880 890 910 920 930 940 950 960 pF1KB3 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KB3 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KB3 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDED 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KB3 SPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEARE 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KB3 HLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRS 1140 1150 1160 1170 1180 1190 1210 pF1KB3 KVQGEQSSETSDSD :::::::::::::: NP_001 KVQGEQSSETSDSD 1200 1210 >>NP_001003694 (OMIM: 602410) peregrin isoform 1 [Homo s (1220 aa) initn: 4751 init1: 4597 opt: 8285 Z-score: 4525.9 bits: 849.5 E(85289): 0 Smith-Waterman score: 8285; 99.5% identity (99.5% similar) in 1220 aa overlap (1-1214:1-1220) 10 20 30 40 50 60 pF1KB3 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 EV------PDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF :: :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB3 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB3 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB3 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB3 DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB3 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB3 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB3 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR 1150 1160 1170 1180 1190 1200 1200 1210 pF1KB3 ALQHRSKVQGEQSSETSDSD :::::::::::::::::::: NP_001 ALQHRSKVQGEQSSETSDSD 1210 1220 >>XP_005265507 (OMIM: 602410) PREDICTED: peregrin isofor (1219 aa) initn: 7603 init1: 4597 opt: 8268 Z-score: 4516.6 bits: 847.8 E(85289): 0 Smith-Waterman score: 8268; 99.4% identity (99.4% similar) in 1220 aa overlap (1-1214:1-1219) 10 20 30 40 50 60 pF1KB3 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 EV------PDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF :: :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_005 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA-EEERLVLL 730 740 750 760 770 780 790 800 810 820 830 pF1KB3 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB3 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF 840 850 860 870 880 890 900 910 920 930 940 950 pF1KB3 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KB3 DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KB3 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KB3 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KB3 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR 1140 1150 1160 1170 1180 1190 1200 1210 pF1KB3 ALQHRSKVQGEQSSETSDSD :::::::::::::::::::: XP_005 ALQHRSKVQGEQSSETSDSD 1200 1210 >>XP_011532403 (OMIM: 602410) PREDICTED: peregrin isofor (1248 aa) initn: 8287 init1: 7262 opt: 7262 Z-score: 3968.8 bits: 746.5 E(85289): 2.5e-214 Smith-Waterman score: 8210; 97.2% identity (97.3% similar) in 1246 aa overlap (1-1212:1-1246) 10 20 30 40 50 60 pF1KB3 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP 970 980 990 1000 1010 1020 1030 1040 1050 1060 pF1KB3 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHS------------------ :::::::::::::::::::::::::::::::::::::::::: XP_011 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSSKFPCPRPGMLGTQCQGL 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 pF1KB3 ----------------MVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDP .::::::::::::::::::::::::::::::::::::::::::: XP_011 ASPPAADPPPLPHSCEVVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDP 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KB3 KMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLG 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 pF1KB3 VNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD :::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD 1210 1220 1230 1240 >>XP_011532404 (OMIM: 602410) PREDICTED: peregrin isofor (1248 aa) initn: 8287 init1: 7262 opt: 7262 Z-score: 3968.8 bits: 746.5 E(85289): 2.5e-214 Smith-Waterman score: 8210; 97.2% identity (97.3% similar) in 1246 aa overlap (1-1212:1-1246) 10 20 30 40 50 60 pF1KB3 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP 970 980 990 1000 1010 1020 1030 1040 1050 1060 pF1KB3 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHS------------------ :::::::::::::::::::::::::::::::::::::::::: XP_011 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSSKFPCPRPGMLGTQCQGL 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 pF1KB3 ----------------MVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDP .::::::::::::::::::::::::::::::::::::::::::: XP_011 ASPPAADPPPLPHSCEVVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDP 1090 1100 1110 1120 1130 1140 1110 1120 1130 1140 1150 1160 pF1KB3 KMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLG 1150 1160 1170 1180 1190 1200 1170 1180 1190 1200 1210 pF1KB3 VNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD :::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD 1210 1220 1230 1240 >>XP_005265506 (OMIM: 602410) PREDICTED: peregrin isofor (1247 aa) initn: 6446 init1: 5309 opt: 7245 Z-score: 3959.6 bits: 744.8 E(85289): 8.2e-214 Smith-Waterman score: 8206; 97.1% identity (97.2% similar) in 1248 aa overlap (1-1214:1-1247) 10 20 30 40 50 60 pF1KB3 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_005 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA-EEERLVLLENQKHL 730 740 750 760 770 790 800 810 820 830 840 pF1KB3 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB3 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK 840 850 860 870 880 890 910 920 930 940 950 960 pF1KB3 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KB3 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP 960 970 980 990 1000 1010 1030 1040 1050 1060 pF1KB3 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHS------------------ :::::::::::::::::::::::::::::::::::::::::: XP_005 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSSKFPCPRPGMLGTQCQGL 1020 1030 1040 1050 1060 1070 1070 1080 1090 1100 pF1KB3 ----------------MVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDP .::::::::::::::::::::::::::::::::::::::::::: XP_005 ASPPAADPPPLPHSCEVVRKSLGRGAGWLSEDEDSPLDALDLVWAKCRGYPSYPALIIDP 1080 1090 1100 1110 1120 1130 1110 1120 1130 1140 1150 1160 pF1KB3 KMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLG 1140 1150 1160 1170 1180 1190 1170 1180 1190 1200 1210 pF1KB3 VNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD 1200 1210 1220 1230 1240 >>NP_001305978 (OMIM: 602410) peregrin isoform 3 [Homo s (1119 aa) initn: 6178 init1: 5988 opt: 6004 Z-score: 3284.6 bits: 619.7 E(85289): 3.2e-176 Smith-Waterman score: 7445; 92.2% identity (92.2% similar) in 1214 aa overlap (1-1214:1-1119) 10 20 30 40 50 60 pF1KB3 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLLENQKHL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGPERHGPS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 SRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPK :::::::::::::::::::::::::::::::: NP_001 SRGSLTPHPAACDKDGQTDSAAEESSSQETSK---------------------------- 850 860 870 910 920 930 940 950 960 pF1KB3 TAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSSDSDSDK NP_001 ------------------------------------------------------------ 970 980 990 1000 1010 1020 pF1KB3 STEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------DLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTP 880 890 900 910 920 1030 1040 1050 1060 1070 1080 pF1KB3 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDED 930 940 950 960 970 980 1090 1100 1110 1120 1130 1140 pF1KB3 SPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEARE 990 1000 1010 1020 1030 1040 1150 1160 1170 1180 1190 1200 pF1KB3 HLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRS 1050 1060 1070 1080 1090 1100 1210 pF1KB3 KVQGEQSSETSDSD :::::::::::::: NP_001 KVQGEQSSETSDSD 1110 >>XP_005265509 (OMIM: 602410) PREDICTED: peregrin isofor (1125 aa) initn: 6365 init1: 4597 opt: 5985 Z-score: 3274.2 bits: 617.8 E(85289): 1.2e-175 Smith-Waterman score: 7423; 91.7% identity (91.7% similar) in 1220 aa overlap (1-1214:1-1125) 10 20 30 40 50 60 pF1KB3 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKMEPVRETGANGTSFSVRKTAYCDIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQVGRDSEDKNWALKEQLKSWQRLRHDLER 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARLLVELIRKREKLKRETIKVQQIAMEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLS 610 620 630 640 650 660 670 680 690 700 710 pF1KB3 EV------PDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF :: :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVTELDEVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIF 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDAAEEERLVLL 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB3 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRAKMIKKEMTALRRKLAHQRETGRDGP 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB3 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLF :::::::::::::::::::::::::::::::::::::: XP_005 ERHGPSSRGSLTPHPAACDKDGQTDSAAEESSSQETSK---------------------- 850 860 870 900 910 920 930 940 950 pF1KB3 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSSS XP_005 ------------------------------------------------------------ 960 970 980 990 1000 1010 pF1KB3 DSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD ::::::::::::::::::::::::::::::::::::::::::::::: XP_005 -------------DLPANGFSGGNQPVKKSFLVYRNDCSLPRSSSDSESSSSSSSSAASD 880 890 900 910 920 1020 1030 1040 1050 1060 1070 pF1KB3 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTSTTPSKQGRGKPSFSRGTFPEDSSEDTSGTENEAYSVGTGRGVGHSMVRKSLGRGAGW 930 940 950 960 970 980 1080 1090 1100 1110 1120 1130 pF1KB3 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSEDEDSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQM 990 1000 1010 1020 1030 1040 1140 1150 1160 1170 1180 1190 pF1KB3 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHR 1050 1060 1070 1080 1090 1100 1200 1210 pF1KB3 ALQHRSKVQGEQSSETSDSD :::::::::::::::::::: XP_005 ALQHRSKVQGEQSSETSDSD 1110 1120 >>NP_001291737 (OMIM: 604589) bromodomain-containing pro (1189 aa) initn: 3927 init1: 1868 opt: 3061 Z-score: 1682.0 bits: 323.3 E(85289): 6e-87 Smith-Waterman score: 3945; 52.3% identity (73.6% similar) in 1218 aa overlap (62-1212:2-1187) 40 50 60 70 80 90 pF1KB3 YKSYSGIEYHLYHYDHDNPPPPQQTPLRKHKKKGRQSRPANKQSPS-PSEVSQSPGREVM ..::: : . . :: : :..:: ::.. NP_001 MRRKGRCHRGSAARHPSSPCSVKHSPTRETL 10 20 30 100 110 120 130 140 150 pF1KB3 SYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPKSGK .:::::::::....::.::::::: :... ::. . .: : .:::::.: : . .. . NP_001 TYAQAQRMVEIEIEGRLHRISIFDPLEIILEDDLTAQEMSECNSNKENSERPPVCLRTKR 40 50 60 70 80 90 160 170 180 190 200 pF1KB3 HKNKE-KRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEEL :::.. :.:. :.. ::.. ::: : .: . :.:: :: ::..:::::::: NP_001 HKNNRVKKKNEALPSAHGTPASASA-LPEPKVRIVEYSPPSAPRRPPVYYKFIEKSAEEL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB3 DEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNAL :.::::::::::: ::.:.::.:: . : . : .::.::::.::::. :....:. ..: NP_001 DNEVEYDMDEEDYAWLEIVNEKRKGDCVPAVSQSMFEFLMDRFEKESHCENQKQGEQQSL 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB3 VDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVD .::::::::: ::::::::::::::::::::::::::::::::::::::.:::: .: .: NP_001 IDEDAVCCICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRARPAD 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB3 CALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYIC :.::::::::::.::: ::.::::::::::: ::::::.::::....:::::::::::.: NP_001 CVLCPNKGGAFKKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLC 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB3 KQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTP ::.: :::::::::::::::::::::.::::::::::.: ..::.::::::::::.::: NP_001 KQKGVGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTGGGTTFSVRKTAYCDVHTP 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB3 PGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEKRAAAP :: .:: : ... : . . : :: :. .. .: : : :::.: ::: :. : NP_001 PGCTRR-PLNIYGDVEMKNGVCRKE----SSVKTVRSTSKVRKKAKKAKKALAEPCAVLP 400 410 420 430 440 510 520 530 540 550 560 pF1KB3 VVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRN .: .: :::.::..:.:...::::.::..: :::: ::: ::::.:::::::. :::::. NP_001 TVCAPYIPPQRLNRIANQVAIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQSQRS 450 460 470 480 490 500 570 580 590 600 610 620 pF1KB3 CDQVGRDSEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQIAMEMQ .: :..... : ::.:: ::::::::::::::.::.::::::::: .::.:.:::.. NP_001 SQQ--RENDEEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQVAMELR 510 520 530 540 550 560 630 640 650 660 670 680 pF1KB3 LTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLN :::. .:::..:.:::.:: . ::..:: :.::::::::::.:::: ::.. ::: : : NP_001 LTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKN 570 580 590 600 610 620 690 700 710 720 730 740 pF1KB3 FDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHI . .:::::.::..::.::::.::.:::::::::.:::.:::::::.....:.. .:::. NP_001 LHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGGVVLRQARREVDSIGLEEASGMHL 630 640 650 660 670 680 750 760 770 780 790 800 pF1KB3 PHSLAGDEATHHTEDAAEEERLVLLENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRRA :. :. : .. . . .::. :. :: .::::. ::. :: . : :.: .::.:: NP_001 PERPAA--APRRPFSWEDVDRLLDPANRAHLGLEEQLRELLDMLDLTCAMKSSGSRSKRA 690 700 710 720 730 740 810 820 830 840 pF1KB3 KMIKKEMTALRRKLAHQRE----TG-------RDG----PE--RHGPSSRGSLTPH---- :..:::.. :: ::..:. :: .:: :: ..: .: .: : NP_001 KLLKKEIALLRNKLSQQHSQPLPTGPGLEGFEEDGAALGPEAGEEGDKSPPKLEPSDALP 750 760 770 780 790 800 850 860 870 pF1KB3 -PAACDK-------------------------DGQTDSAAEESS--------SQETSKGL :. . :... :: .:. ..:.: NP_001 LPSNSETNSEPPTLKPVELNPEQSKLFKRVTFDNESHSACTQSALVSGRPPEPTRASSGD 810 820 830 840 850 860 880 890 900 910 920 pF1KB3 GPNMSST----PAHEVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRESQMT-PSHGGSPVG : ... :: .:.::::::: :. :...::: :: :.: : :. : . NP_001 VPAAAASAVAEPASDVNRRTSVLFCKS--KSVSPPK----SAKNTETQPTSPQLGTKTFL 870 880 890 900 910 930 940 950 960 970 980 pF1KB3 PPQLPIMSSLRQ-RKRGRSPRPSSSSDSDSDKSTEDPPMDLPA---NGFSGGNQPVKKSF :: . .: : :::.:: . .::. :.: : : :::.:. . . . NP_001 SVVLPRLETLLQPRKRSRS------TCGDSEVEEESPGKRLDAGLTNGFGGARSEQEPGG 920 930 940 950 960 990 1000 1010 1020 1030 1040 pF1KB3 LVYRNDCSLPRSSSDSESSSSSSSSAASDRTSTTPSKQGRGKPSFSRGTFPEDSSEDTSG . :. . :: :::: :::.: : . ..: : :::::.. : :: :: : NP_001 GLGRK--ATPRRRCASESSISSSNSPLCDSSFNAP-KCGRGKPALVRRHTLEDRSELISC 970 980 990 1000 1010 1020 1050 1060 1070 1080 1090 1100 pF1KB3 TENEAYSVGTGRGVGHSMVRKSLGRGAGWLSEDED-SPLDALDLVWAKCRGYPSYPALII :: :. . . . .:... :.: : : :. : .::::: :::::::::: NP_001 IENGNYAKA-------ARIAAEVGQSSMWISTDAAASVLEPLKVVWAKCSGYPSYPALII 1030 1040 1050 1060 1070 1110 1120 1130 1140 1150 1160 pF1KB3 DPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVP :::::: :.:: ::.:::.:::.::.: .. :.:.:::::::::.:::::..:.:: NP_001 DPKMPRVPGHHNGVTIPAPPLDVLKIGEHMQTKSDEKLFLVLFFDNKRSWQWLPKSKMVP 1080 1090 1100 1110 1120 1130 1170 1180 1190 1200 1210 pF1KB3 LGVNQDLDKEKMLEGRKSNIRKSVQIAYHRALQHRSKVQGEQSSETSDSD ::... .:: ::.:::.:.:::.:.::. ::..: :.:.:: .:. :: NP_001 LGIDETIDKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGEPTSDLSDID 1140 1150 1160 1170 1180 1214 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:07:48 2016 done: Thu Nov 3 12:07:51 2016 Total Scan time: 18.310 Total Display time: 0.530 Function used was FASTA [36.3.4 Apr, 2011]