FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3031, 593 aa 1>>>pF1KB3031 593 - 593 aa - 593 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6720+/-0.000999; mu= 18.6630+/- 0.060 mean_var=110.7932+/-23.037, 0's: 0 Z-trim(107.9): 187 B-trim: 842 in 2/50 Lambda= 0.121848 statistics sampled from 9615 (9840) to 9615 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.302), width: 16 Scan time: 3.490 The best scores are: opt bits E(32554) CCDS9163.1 PTPN11 gene_id:5781|Hs108|chr12 ( 593) 4005 715.4 5.1e-206 CCDS81741.1 PTPN11 gene_id:5781|Hs108|chr12 ( 597) 3987 712.2 4.6e-205 CCDS58280.1 PTPN11 gene_id:5781|Hs108|chr12 ( 460) 3114 558.6 6.1e-159 CCDS41744.1 PTPN6 gene_id:5777|Hs108|chr12 ( 597) 2205 399.0 9.2e-111 CCDS44820.1 PTPN6 gene_id:5777|Hs108|chr12 ( 595) 2197 397.5 2.4e-110 CCDS44821.1 PTPN6 gene_id:5777|Hs108|chr12 ( 624) 2197 397.6 2.5e-110 CCDS47473.1 PTPRK gene_id:5796|Hs108|chr6 (1446) 727 139.5 2.8e-32 CCDS78179.1 PTPRK gene_id:5796|Hs108|chr6 (1462) 727 139.5 2.8e-32 CCDS56505.1 PTPRZ1 gene_id:5803|Hs108|chr7 (1448) 647 125.5 4.7e-28 CCDS34740.1 PTPRZ1 gene_id:5803|Hs108|chr7 (2315) 644 125.2 9.5e-28 CCDS44098.2 PTPRU gene_id:10076|Hs108|chr1 (1440) 617 120.2 1.8e-26 CCDS75517.1 PTPRK gene_id:5796|Hs108|chr6 (1439) 615 119.8 2.3e-26 CCDS5137.1 PTPRK gene_id:5796|Hs108|chr6 (1440) 615 119.8 2.3e-26 CCDS75813.1 PTPRD gene_id:5789|Hs108|chr9 (1496) 610 119.0 4.4e-26 CCDS55288.1 PTPRD gene_id:5789|Hs108|chr9 (1502) 610 119.0 4.4e-26 CCDS55289.1 PTPRD gene_id:5789|Hs108|chr9 (1505) 610 119.0 4.4e-26 CCDS6472.2 PTPRD gene_id:5789|Hs108|chr9 (1505) 610 119.0 4.4e-26 CCDS55290.1 PTPRD gene_id:5789|Hs108|chr9 (1506) 610 119.0 4.4e-26 CCDS43786.1 PTPRD gene_id:5789|Hs108|chr9 (1912) 610 119.1 5.2e-26 CCDS13039.1 PTPRA gene_id:5786|Hs108|chr20 ( 793) 604 117.6 5.9e-26 CCDS13038.1 PTPRA gene_id:5786|Hs108|chr20 ( 802) 604 117.6 6e-26 CCDS12139.1 PTPRS gene_id:5802|Hs108|chr19 (1501) 604 117.9 9.2e-26 CCDS74265.1 PTPRS gene_id:5802|Hs108|chr19 (1505) 604 117.9 9.2e-26 CCDS12140.1 PTPRS gene_id:5802|Hs108|chr19 (1910) 604 118.0 1.1e-25 CCDS45930.1 PTPRS gene_id:5802|Hs108|chr19 (1948) 604 118.0 1.1e-25 CCDS42874.1 PTPRT gene_id:11122|Hs108|chr20 (1441) 601 117.4 1.3e-25 CCDS68127.1 PTPRT gene_id:11122|Hs108|chr20 (1460) 601 117.4 1.3e-25 CCDS7658.1 PTPRE gene_id:5791|Hs108|chr10 ( 642) 592 115.4 2.2e-25 CCDS7657.1 PTPRE gene_id:5791|Hs108|chr10 ( 700) 592 115.5 2.3e-25 CCDS11840.1 PTPRM gene_id:5797|Hs108|chr18 (1452) 593 116.0 3.4e-25 CCDS58613.1 PTPRM gene_id:5797|Hs108|chr18 (1465) 593 116.0 3.4e-25 CCDS78294.1 PTPRN2 gene_id:5799|Hs108|chr7 ( 977) 587 114.7 5.4e-25 CCDS5949.1 PTPRN2 gene_id:5799|Hs108|chr7 ( 986) 587 114.8 5.4e-25 CCDS5948.1 PTPRN2 gene_id:5799|Hs108|chr7 ( 998) 587 114.8 5.5e-25 CCDS5947.1 PTPRN2 gene_id:5799|Hs108|chr7 (1015) 587 114.8 5.6e-25 CCDS490.2 PTPRF gene_id:5792|Hs108|chr1 (1898) 586 114.9 9.7e-25 CCDS489.2 PTPRF gene_id:5792|Hs108|chr1 (1907) 586 114.9 9.7e-25 CCDS2895.1 PTPRG gene_id:5793|Hs108|chr3 (1445) 584 114.4 1e-24 CCDS335.1 PTPRU gene_id:10076|Hs108|chr1 (1436) 571 112.1 5e-24 CCDS334.1 PTPRU gene_id:10076|Hs108|chr1 (1446) 571 112.1 5e-24 CCDS56167.1 PTPRN gene_id:5798|Hs108|chr2 ( 889) 566 111.0 6.6e-24 CCDS56168.1 PTPRN gene_id:5798|Hs108|chr2 ( 950) 566 111.0 6.9e-24 CCDS2440.1 PTPRN gene_id:5798|Hs108|chr2 ( 979) 566 111.1 7e-24 CCDS55845.1 PTPRB gene_id:5787|Hs108|chr12 (1907) 557 109.8 3.3e-23 CCDS55846.1 PTPRB gene_id:5787|Hs108|chr12 (1907) 557 109.8 3.3e-23 CCDS44944.1 PTPRB gene_id:5787|Hs108|chr12 (1997) 557 109.8 3.4e-23 CCDS81713.1 PTPRB gene_id:5787|Hs108|chr12 (2127) 557 109.8 3.6e-23 CCDS44943.1 PTPRB gene_id:5787|Hs108|chr12 (2215) 557 109.8 3.7e-23 CCDS11864.1 PTPN2 gene_id:5771|Hs108|chr18 ( 353) 543 106.6 5.7e-23 CCDS11863.1 PTPN2 gene_id:5771|Hs108|chr18 ( 387) 543 106.6 6.1e-23 >>CCDS9163.1 PTPN11 gene_id:5781|Hs108|chr12 (593 aa) initn: 4005 init1: 4005 opt: 4005 Z-score: 3812.1 bits: 715.4 E(32554): 5.1e-206 Smith-Waterman score: 4005; 100.0% identity (100.0% similar) in 593 aa overlap (1-593:1-593) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 EYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 EYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR 550 560 570 580 590 >>CCDS81741.1 PTPN11 gene_id:5781|Hs108|chr12 (597 aa) initn: 2763 init1: 2733 opt: 3987 Z-score: 3795.0 bits: 712.2 E(32554): 4.6e-205 Smith-Waterman score: 3987; 99.3% identity (99.3% similar) in 597 aa overlap (1-593:1-597) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQ----GNTERTVW :::::::::::::::::::::::::::::::::::::::::::::::: :::::::: CCDS81 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR 550 560 570 580 590 >>CCDS58280.1 PTPN11 gene_id:5781|Hs108|chr12 (460 aa) initn: 3114 init1: 3114 opt: 3114 Z-score: 2967.0 bits: 558.6 E(32554): 6.1e-159 Smith-Waterman score: 3114; 100.0% identity (100.0% similar) in 459 aa overlap (1-459:1-459) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR ::::::::::::::::::::::::::::::::::::::: CCDS58 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCR 430 440 450 460 490 500 510 520 530 540 pF1KB3 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH >>CCDS41744.1 PTPN6 gene_id:5777|Hs108|chr12 (597 aa) initn: 2365 init1: 939 opt: 2205 Z-score: 2102.0 bits: 399.0 E(32554): 9.2e-111 Smith-Waterman score: 2205; 58.6% identity (81.0% similar) in 548 aa overlap (1-547:1-543) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG : :: ::: ...:..::.:: ::: ::::::::..: :::.:::: . ::::.:::.: CCDS41 MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :.::::::::::::.:::.:: ...: :....: .:.:::::::.:::::::.:::.:: CCDS41 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKY .:: :: ::. .:::::: :.:::::::: . :. ... :. .:::. . :. .: CCDS41 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRY 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAET ::: : ::::::::::.::. . :. :. . :.:: .::.:::.::.:: ::.: :. CCDS41 TVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQES 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE : .: :::::::.::.:: : :..: :::: :::.::::::::::::.::.:. : : CCDS41 EDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE : ::::::: : .. .:. :.:::.::::. ::::::.:..:::::::::::.: CCDS41 PGSDYINANYIKNQLLGPDENA---KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTRE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH ::.:..::: :::. . :: . : : : . .: :: :..: . .:. : .:.:. CCDS41 VEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQ 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII . .::::::::.:::::.::......:::. :::..::::::::::::.::::.:.. : CCDS41 YLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG ::.:::::. :::::::.::::::::::::.:::.:. ..::: ....: :..: . CCDS41 STKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQE 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 HEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR :: :: : CCDS41 SEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLK 540 550 560 570 580 590 >>CCDS44820.1 PTPN6 gene_id:5777|Hs108|chr12 (595 aa) initn: 2368 init1: 939 opt: 2197 Z-score: 2094.4 bits: 397.5 E(32554): 2.4e-110 Smith-Waterman score: 2197; 58.6% identity (81.2% similar) in 544 aa overlap (5-547:3-541) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::: ...:..::.:: ::: ::::::::..: :::.:::: . ::::.:::.: CCDS44 MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :.::::::::::::.:::.:: ...: :....: .:.:::::::.:::::::.:::.:: CCDS44 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG 60 70 80 90 100 110 130 140 150 160 170 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKY .:: :: ::. .:::::: :.:::::::: . :. ... :. .:::. . :. .: CCDS44 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAET ::: : ::::::::::.::. . :. :. . :.:: .::.:::.::.:: ::.: :. CCDS44 TVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQES 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE : .: :::::::.::.:: : :..: :::: :::.::::::::::::.::.:. : : CCDS44 EDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE : ::::::: : .. .:.: .:::.::::. ::::::.:..:::::::::::.: CCDS44 PGSDYINANYIKNQLLGPDENAK---TYIASQGCLEATVNDFWQMAWQENSRVIVMTTRE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH ::.:..::: :::. . :: . : : : . .: :: :..: . .:. : .:.:. CCDS44 VEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQ 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII . .::::::::.:::::.::......:::. :::..::::::::::::.::::.:.. : CCDS44 YLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG ::.:::::. :::::::.::::::::::::.:::.:. ..::: ....: :..: . CCDS44 STKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQE 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 HEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR :: :: : CCDS44 SEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLK 540 550 560 570 580 590 >>CCDS44821.1 PTPN6 gene_id:5777|Hs108|chr12 (624 aa) initn: 2368 init1: 939 opt: 2197 Z-score: 2094.2 bits: 397.6 E(32554): 2.5e-110 Smith-Waterman score: 2197; 58.6% identity (81.2% similar) in 544 aa overlap (5-547:3-541) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::: ...:..::.:: ::: ::::::::..: :::.:::: . ::::.:::.: CCDS44 MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :.::::::::::::.:::.:: ...: :....: .:.:::::::.:::::::.:::.:: CCDS44 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG 60 70 80 90 100 110 130 140 150 160 170 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKY .:: :: ::. .:::::: :.:::::::: . :. ... :. .:::. . :. .: CCDS44 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAET ::: : ::::::::::.::. . :. :. . :.:: .::.:::.::.:: ::.: :. CCDS44 TVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQES 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE : .: :::::::.::.:: : :..: :::: :::.::::::::::::.::.:. : : CCDS44 EDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE : ::::::: : .. .:.: .:::.::::. ::::::.:..:::::::::::.: CCDS44 PGSDYINANYIKNQLLGPDENAK---TYIASQGCLEATVNDFWQMAWQENSRVIVMTTRE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH ::.:..::: :::. . :: . : : : . .: :: :..: . .:. : .:.:. CCDS44 VEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQ 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII . .::::::::.:::::.::......:::. :::..::::::::::::.::::.:.. : CCDS44 YLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG ::.:::::. :::::::.::::::::::::.:::.:. ..::: ....: :..: . CCDS44 STKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQE 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 HEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR :: :: : CCDS44 SEYGNITYPPAMKNAHAKASRTSSKSLESSAGTVAASPVRRGGQRGLPVPGPPVLSPDLH 540 550 560 570 580 590 >>CCDS47473.1 PTPRK gene_id:5796|Hs108|chr6 (1446 aa) initn: 658 init1: 212 opt: 727 Z-score: 693.1 bits: 139.5 E(32554): 2.8e-32 Smith-Waterman score: 727; 41.2% identity (68.6% similar) in 306 aa overlap (213-518:856-1145) 190 200 210 220 230 240 pF1KB3 GGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDK ..: .: ... : . . . .: .:.:. CCDS47 HNFSPRYENHSATAESSRLLDVPRYLCEGTESPYQTGQLHPAIRVADLLQHINLMKTSDS 830 840 850 860 870 880 250 260 270 280 290 300 pF1KB3 VKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVS :: ::.:.. . . : .....:. :::: ::. .::.::.:. . ..: : CCDS47 Y--GFKEEYESFFEGQSA---SWDVAKKDQNRAKNRYGNIIAYDHSRVILQPVE-DDPSS 890 900 910 920 930 310 320 330 340 350 360 pF1KB3 DYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVER :::::: : . . . ..:.. :::::: ...:: :::::..::.: :::.:. :: CCDS47 DYINANYI-DIWLYRDGYQRPSH-YIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEV 940 950 960 970 980 990 370 380 390 400 410 420 pF1KB3 GKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRT :. :: :::::. . :: ..: :. .:..: . : . : : : : :.:: CCDS47 GRVKCYKYWPDDTEV--YGDFKVTCVEMEPLAEYVVRTFTLERRGY-NEIREVKQFHFTG 1000 1010 1020 1030 1040 1050 430 440 450 460 470 480 pF1KB3 WPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREK ::::::: :.:.:...: : . .:::.::::::: :::: .:::::..:. ... CCDS47 WPDHGVPYHATGLLSFIRRV--KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAERE 1060 1070 1080 1090 1100 1110 490 500 510 520 530 540 pF1KB3 GVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEY :: .:. . .. .::.: .::::: :: ::. :. CCDS47 GV---VDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMI 1120 1130 1140 1150 1160 550 560 570 580 590 pF1KB3 TNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR CCDS47 RIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITI 1170 1180 1190 1200 1210 1220 >-- initn: 214 init1: 124 opt: 392 Z-score: 374.8 bits: 80.6 E(32554): 1.5e-14 Smith-Waterman score: 392; 28.6% identity (62.7% similar) in 276 aa overlap (254-524:1194-1445) 230 240 250 260 270 280 pF1KB3 AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNIL :: ..:.. . .:..:::. ..: CCDS47 AYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSI------ACLPRNHDKNRFMDML 1170 1180 1190 1200 1210 290 300 310 320 330 340 pF1KB3 PFDHTR--VVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDF : :. .. ::. :.:::: .. .. . ..:.:: : :::.:: CCDS47 PPDRCLPFLITIDGES----SNYINAALM--------DSYRQPAAFIVTQYPLPNTVKDF 1220 1230 1240 1250 1260 350 360 370 380 390 400 pF1KB3 WRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLREL ::.:.. . ::: . ::. ... : .:::.: :. :: ..:. .. : : : . CCDS47 WRLVYDYGCTSIVMLN-EVDLSQG-CPQYWPEEGMLR-YGPIQVECMSCSMDCDVINRIF 1270 1280 1290 1300 1310 1320 410 420 430 440 450 pF1KB3 KLSKVGQGNTERT-VWQYHFRTWPDHG-VPSDPGGVLDFLEEVHHKQESIMDA-GPVVVH .. .. . . : :... : .: ::.. . : .. .:.. :: .. : ...: CCDS47 RICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIH 1330 1340 1350 1360 1370 1380 460 470 480 490 500 510 pF1KB3 CSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV : : ::.: : .: :.........: .:: .... .:... .::.. :::: : .. CCDS47 CLNGGGRSGMFCAIGIVVEMVKRQNV---VDVFHAVKTLRNSKPNMVEAPEQYRFCYDVA 1390 1400 1410 1420 1430 520 530 540 550 560 570 pF1KB3 QHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSAR .:.:. CCDS47 LEYLESS 1440 >>CCDS78179.1 PTPRK gene_id:5796|Hs108|chr6 (1462 aa) initn: 658 init1: 212 opt: 727 Z-score: 693.0 bits: 139.5 E(32554): 2.8e-32 Smith-Waterman score: 727; 41.2% identity (68.6% similar) in 306 aa overlap (213-518:872-1161) 190 200 210 220 230 240 pF1KB3 GGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDK ..: .: ... : . . . .: .:.:. CCDS78 VLVPITDENHSATAESSRLLDVPRYLCEGTESPYQTGQLHPAIRVADLLQHINLMKTSDS 850 860 870 880 890 900 250 260 270 280 290 300 pF1KB3 VKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVS :: ::.:.. . . : .....:. :::: ::. .::.::.:. . ..: : CCDS78 Y--GFKEEYESFFEGQSA---SWDVAKKDQNRAKNRYGNIIAYDHSRVILQPVE-DDPSS 910 920 930 940 950 310 320 330 340 350 360 pF1KB3 DYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVER :::::: : . . . ..:.. :::::: ...:: :::::..::.: :::.:. :: CCDS78 DYINANYI-DIWLYRDGYQRPSH-YIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEV 960 970 980 990 1000 1010 370 380 390 400 410 420 pF1KB3 GKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRT :. :: :::::. . :: ..: :. .:..: . : . : : : : :.:: CCDS78 GRVKCYKYWPDDTEV--YGDFKVTCVEMEPLAEYVVRTFTLERRGY-NEIREVKQFHFTG 1020 1030 1040 1050 1060 1070 430 440 450 460 470 480 pF1KB3 WPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREK ::::::: :.:.:...: : . .:::.::::::: :::: .:::::..:. ... CCDS78 WPDHGVPYHATGLLSFIRRV--KLSNPPSAGPIVVHCSAGAGRTGCYIVIDIMLDMAERE 1080 1090 1100 1110 1120 490 500 510 520 530 540 pF1KB3 GVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEY :: .:. . .. .::.: .::::: :: ::. :. CCDS78 GV---VDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACLCGETAIPVCEFKAAYFDMI 1130 1140 1150 1160 1170 1180 550 560 570 580 590 pF1KB3 TNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR CCDS78 RIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITI 1190 1200 1210 1220 1230 1240 >-- initn: 214 init1: 124 opt: 392 Z-score: 374.7 bits: 80.6 E(32554): 1.5e-14 Smith-Waterman score: 392; 28.6% identity (62.7% similar) in 276 aa overlap (254-524:1210-1461) 230 240 250 260 270 280 pF1KB3 AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNIL :: ..:.. . .:..:::. ..: CCDS78 AYFDMIRIDSQTNSSHLKDEFQTLNSVTPRLQAEDCSI------ACLPRNHDKNRFMDML 1180 1190 1200 1210 1220 1230 290 300 310 320 330 340 pF1KB3 PFDHTR--VVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDF : :. .. ::. :.:::: .. .. . ..:.:: : :::.:: CCDS78 PPDRCLPFLITIDGES----SNYINAALM--------DSYRQPAAFIVTQYPLPNTVKDF 1240 1250 1260 1270 1280 350 360 370 380 390 400 pF1KB3 WRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLREL ::.:.. . ::: . ::. ... : .:::.: :. :: ..:. .. : : : . CCDS78 WRLVYDYGCTSIVMLN-EVDLSQG-CPQYWPEEGMLR-YGPIQVECMSCSMDCDVINRIF 1290 1300 1310 1320 1330 410 420 430 440 450 pF1KB3 KLSKVGQGNTERT-VWQYHFRTWPDHG-VPSDPGGVLDFLEEVHHKQESIMDA-GPVVVH .. .. . . : :... : .: ::.. . : .. .:.. :: .. : ...: CCDS78 RICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTIIH 1340 1350 1360 1370 1380 1390 460 470 480 490 500 510 pF1KB3 CSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAV : : ::.: : .: :.........: .:: .... .:... .::.. :::: : .. CCDS78 CLNGGGRSGMFCAIGIVVEMVKRQNV---VDVFHAVKTLRNSKPNMVEAPEQYRFCYDVA 1400 1410 1420 1430 1440 1450 520 530 540 550 560 570 pF1KB3 QHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSAR .:.:. CCDS78 LEYLESS 1460 >>CCDS56505.1 PTPRZ1 gene_id:5803|Hs108|chr7 (1448 aa) initn: 620 init1: 203 opt: 647 Z-score: 617.1 bits: 125.5 E(32554): 4.7e-28 Smith-Waterman score: 647; 40.6% identity (69.8% similar) in 278 aa overlap (246-515:856-1119) 220 230 240 250 260 270 pF1KB3 LNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKN :: :::: .:. : . ... .::. CCDS56 PTPIFPISDDVGAIPIKHFPKHVADLHASSGFTEEFEEVQSCTVDLGITADSSNHPDNKH 830 840 850 860 870 880 280 290 300 310 320 330 pF1KB3 KNRYKNILPFDHTRVVLHD-GDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCL :::: ::. .::.:: : . .. . ..:::::: . . ..:: .:::.:: : CCDS56 KNRYINIVAYDHSRVKLAQLAEKDGKLTDYINANYVD-------GYNRPK-AYIAAQGPL 890 900 910 920 930 340 350 360 370 380 390 pF1KB3 QNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRV--RNVKESA ..:..:::::....: .:::: :. ::.:. :: .::: . . .::: . : ..:. : CCDS56 KSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPADGS-EEYGNFLVTQKSVQVLA 940 950 960 970 980 990 400 410 420 430 440 pF1KB3 AH---DYTLRELKLSKVGQGN--TERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQE . ..:::. :..: .: . . :.: :::. ::: ::: :: :.... . .. CCDS56 YYTVRNFTLRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYSLPVLTFVRKAAYAKR 1000 1010 1020 1030 1040 1050 450 460 470 480 490 500 pF1KB3 SIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQT . ::::::::::.:::::.::.: ... :...:. ... .. .::::. .::: CCDS56 HAV--GPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGT---VNIFGFLKHIRSQRNYLVQT 1060 1070 1080 1090 1100 1110 510 520 530 540 550 560 pF1KB3 EAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTP : :: ::. CCDS56 EEQYVFIHDTLVEAILSKETEVLDSHIHAYVNALLIPGPAGKTKLEKQFQLLSQSNIQQS 1120 1130 1140 1150 1160 1170 >>CCDS34740.1 PTPRZ1 gene_id:5803|Hs108|chr7 (2315 aa) initn: 552 init1: 203 opt: 644 Z-score: 611.7 bits: 125.2 E(32554): 9.5e-28 Smith-Waterman score: 644; 40.7% identity (69.1% similar) in 285 aa overlap (246-515:1716-1986) 220 230 240 250 260 pF1KB3 LNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQ-----QECK--LLYSRKEG :: ::::::.. : : : . . CCDS34 PTPIFPISDDVGAIPIKHFPKHVADLHASSGFTEEFETLKEFYQEVQSCTVDLGITADSS 1690 1700 1710 1720 1730 1740 270 280 290 300 310 320 pF1KB3 QRQENKNKNRYKNILPFDHTRVVLHD-GDPNEPVSDYINANIIMPEFETKCNNSKPKKSY .. .::.:::: ::. .::.:: : . .. . ..:::::: . . ..:: .: CCDS34 NHPDNKHKNRYINIVAYDHSRVKLAQLAEKDGKLTDYINANYVD-------GYNRPK-AY 1750 1760 1770 1780 1790 330 340 350 360 370 380 pF1KB3 IATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRV-- ::.:: :..:..:::::....: .:::: :. ::.:. :: .::: . . .::: . : CCDS34 IAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPADGS-EEYGNFLVTQ 1800 1810 1820 1830 1840 1850 390 400 410 420 430 440 pF1KB3 RNVKESAAH---DYTLRELKLSKVGQGN--TERTVWQYHFRTWPDHGVPSDPGGVLDFLE ..:. : . ..:::. :..: .: . . :.: :::. ::: ::: :: :.. CCDS34 KSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYSLPVLTFVR 1860 1870 1880 1890 1900 1910 450 460 470 480 490 500 pF1KB3 EVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQ .. . .. . ::::::::::.:::::.::.: ... :...:. ... .. .::: CCDS34 KAAYAKRHAV--GPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGT---VNIFGFLKHIRSQ 1920 1930 1940 1950 1960 1970 510 520 530 540 550 560 pF1KB3 RSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPL :. .:::: :: ::. CCDS34 RNYLVQTEEQYVFIHDTLVEAILSKETEVLDSHIHAYVNALLIPGPAGKTKLEKQFQLLS 1980 1990 2000 2010 2020 2030 593 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:10:45 2016 done: Thu Nov 3 12:10:45 2016 Total Scan time: 3.490 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]