FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3031, 593 aa 1>>>pF1KB3031 593 - 593 aa - 593 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5854+/-0.000418; mu= 19.7066+/- 0.026 mean_var=151.8121+/-36.200, 0's: 0 Z-trim(115.1): 540 B-trim: 2812 in 2/51 Lambda= 0.104093 statistics sampled from 24709 (25412) to 24709 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.298), width: 16 Scan time: 10.720 The best scores are: opt bits E(85289) NP_002825 (OMIM: 151100,156250,163950,176876,60778 ( 593) 4005 614.1 4e-175 NP_001317366 (OMIM: 151100,156250,163950,176876,60 ( 597) 3987 611.4 2.6e-174 XP_016875211 (OMIM: 151100,156250,163950,176876,60 ( 592) 3986 611.3 2.9e-174 XP_011536915 (OMIM: 151100,156250,163950,176876,60 ( 596) 3968 608.6 1.9e-173 NP_542168 (OMIM: 151100,156250,163950,176876,60778 ( 460) 3114 480.2 6.6e-135 NP_536858 (OMIM: 176883) tyrosine-protein phosphat ( 597) 2205 343.8 9.5e-94 XP_011519290 (OMIM: 176883) PREDICTED: tyrosine-pr ( 597) 2205 343.8 9.5e-94 NP_002822 (OMIM: 176883) tyrosine-protein phosphat ( 595) 2197 342.6 2.2e-93 NP_536859 (OMIM: 176883) tyrosine-protein phosphat ( 624) 2197 342.7 2.2e-93 XP_006719057 (OMIM: 176883) PREDICTED: tyrosine-pr ( 481) 1639 258.7 3.2e-68 XP_016866639 (OMIM: 602545) PREDICTED: receptor-ty ( 723) 727 122.0 7e-27 XP_016866638 (OMIM: 602545) PREDICTED: receptor-ty ( 727) 727 122.0 7e-27 XP_016866636 (OMIM: 602545) PREDICTED: receptor-ty (1374) 727 122.4 1e-26 XP_016866634 (OMIM: 602545) PREDICTED: receptor-ty (1375) 727 122.4 1e-26 XP_016866635 (OMIM: 602545) PREDICTED: receptor-ty (1375) 727 122.4 1e-26 XP_011534320 (OMIM: 602545) PREDICTED: receptor-ty (1391) 727 122.4 1e-26 XP_011534319 (OMIM: 602545) PREDICTED: receptor-ty (1391) 727 122.4 1e-26 XP_006715600 (OMIM: 602545) PREDICTED: receptor-ty (1445) 727 122.4 1e-26 NP_001129120 (OMIM: 602545) receptor-type tyrosine (1446) 727 122.4 1e-26 XP_011534317 (OMIM: 602545) PREDICTED: receptor-ty (1458) 727 122.4 1e-26 XP_011534316 (OMIM: 602545) PREDICTED: receptor-ty (1461) 727 122.4 1e-26 NP_001278910 (OMIM: 602545) receptor-type tyrosine (1462) 727 122.4 1e-26 NP_001193768 (OMIM: 176891,600263) receptor-type t (1448) 647 110.4 4.3e-23 XP_005250576 (OMIM: 176891,600263) PREDICTED: rece (2308) 647 110.7 5.6e-23 NP_001193767 (OMIM: 176891,600263) receptor-type t (1455) 644 109.9 5.9e-23 XP_016867966 (OMIM: 176891,600263) PREDICTED: rece (2301) 644 110.2 7.7e-23 NP_002842 (OMIM: 176891,600263) receptor-type tyro (2315) 644 110.2 7.7e-23 XP_016855484 (OMIM: 602454) PREDICTED: receptor-ty (1187) 617 105.8 8.7e-22 NP_573438 (OMIM: 602454) receptor-type tyrosine-pr (1440) 617 105.9 9.7e-22 XP_006710332 (OMIM: 602454) PREDICTED: receptor-ty (1442) 617 105.9 9.8e-22 XP_016855481 (OMIM: 602454) PREDICTED: receptor-ty (1452) 617 105.9 9.8e-22 XP_016866637 (OMIM: 602545) PREDICTED: receptor-ty (1368) 615 105.6 1.2e-21 NP_001278913 (OMIM: 602545) receptor-type tyrosine (1439) 615 105.6 1.2e-21 NP_002835 (OMIM: 602545) receptor-type tyrosine-pr (1440) 615 105.6 1.2e-21 XP_011534318 (OMIM: 602545) PREDICTED: receptor-ty (1456) 615 105.6 1.2e-21 XP_006716902 (OMIM: 601598) PREDICTED: receptor-ty (1491) 610 104.9 2.1e-21 XP_006716901 (OMIM: 601598) PREDICTED: receptor-ty (1495) 610 104.9 2.1e-21 XP_006716900 (OMIM: 601598) PREDICTED: receptor-ty (1496) 610 104.9 2.1e-21 NP_569077 (OMIM: 601598) receptor-type tyrosine-pr (1496) 610 104.9 2.1e-21 XP_016870483 (OMIM: 601598) PREDICTED: receptor-ty (1501) 610 104.9 2.1e-21 XP_016870484 (OMIM: 601598) PREDICTED: receptor-ty (1501) 610 104.9 2.1e-21 NP_001035802 (OMIM: 601598) receptor-type tyrosine (1502) 610 104.9 2.1e-21 XP_016870482 (OMIM: 601598) PREDICTED: receptor-ty (1502) 610 104.9 2.1e-21 XP_006716898 (OMIM: 601598) PREDICTED: receptor-ty (1502) 610 104.9 2.1e-21 XP_016870481 (OMIM: 601598) PREDICTED: receptor-ty (1503) 610 104.9 2.1e-21 XP_006716896 (OMIM: 601598) PREDICTED: receptor-ty (1505) 610 104.9 2.1e-21 NP_001164496 (OMIM: 601598) receptor-type tyrosine (1505) 610 104.9 2.1e-21 XP_006716895 (OMIM: 601598) PREDICTED: receptor-ty (1505) 610 104.9 2.1e-21 NP_569075 (OMIM: 601598) receptor-type tyrosine-pr (1505) 610 104.9 2.1e-21 XP_006716897 (OMIM: 601598) PREDICTED: receptor-ty (1505) 610 104.9 2.1e-21 >>NP_002825 (OMIM: 151100,156250,163950,176876,607785) t (593 aa) initn: 4005 init1: 4005 opt: 4005 Z-score: 3265.0 bits: 614.1 E(85289): 4e-175 Smith-Waterman score: 4005; 100.0% identity (100.0% similar) in 593 aa overlap (1-593:1-593) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 EYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR 550 560 570 580 590 >>NP_001317366 (OMIM: 151100,156250,163950,176876,607785 (597 aa) initn: 2763 init1: 2733 opt: 3987 Z-score: 3250.4 bits: 611.4 E(85289): 2.6e-174 Smith-Waterman score: 3987; 99.3% identity (99.3% similar) in 597 aa overlap (1-593:1-597) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQ----GNTERTVW :::::::::::::::::::::::::::::::::::::::::::::::: :::::::: NP_001 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB3 QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR 550 560 570 580 590 >>XP_016875211 (OMIM: 151100,156250,163950,176876,607785 (592 aa) initn: 3697 init1: 3697 opt: 3986 Z-score: 3249.6 bits: 611.3 E(85289): 2.9e-174 Smith-Waterman score: 3986; 99.8% identity (99.8% similar) in 593 aa overlap (1-593:1-592) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_016 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVR-NGAVTHIKIQNTG 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB3 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB3 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB3 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH 480 490 500 510 520 530 550 560 570 580 590 pF1KB3 EYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR 540 550 560 570 580 590 >>XP_011536915 (OMIM: 151100,156250,163950,176876,607785 (596 aa) initn: 2455 init1: 2425 opt: 3968 Z-score: 3234.9 bits: 608.6 E(85289): 1.9e-173 Smith-Waterman score: 3968; 99.2% identity (99.2% similar) in 597 aa overlap (1-593:1-596) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_011 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVR-NGAVTHIKIQNTG 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB3 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 300 310 320 330 340 350 370 380 390 400 410 pF1KB3 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQ----GNTERTVW :::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_011 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR 540 550 560 570 580 590 >>NP_542168 (OMIM: 151100,156250,163950,176876,607785) t (460 aa) initn: 3114 init1: 3114 opt: 3114 Z-score: 2543.0 bits: 480.2 E(85289): 6.6e-135 Smith-Waterman score: 3114; 100.0% identity (100.0% similar) in 459 aa overlap (1-459:1-459) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR ::::::::::::::::::::::::::::::::::::::: NP_542 RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCR 430 440 450 460 490 500 510 520 530 540 pF1KB3 EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH >>NP_536858 (OMIM: 176883) tyrosine-protein phosphatase (597 aa) initn: 2365 init1: 939 opt: 2205 Z-score: 1804.1 bits: 343.8 E(85289): 9.5e-94 Smith-Waterman score: 2205; 58.6% identity (81.0% similar) in 548 aa overlap (1-547:1-543) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG : :: ::: ...:..::.:: ::: ::::::::..: :::.:::: . ::::.:::.: NP_536 MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :.::::::::::::.:::.:: ...: :....: .:.:::::::.:::::::.:::.:: NP_536 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKY .:: :: ::. .:::::: :.:::::::: . :. ... :. .:::. . :. .: NP_536 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRY 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAET ::: : ::::::::::.::. . :. :. . :.:: .::.:::.::.:: ::.: :. NP_536 TVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQES 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE : .: :::::::.::.:: : :..: :::: :::.::::::::::::.::.:. : : NP_536 EDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE : ::::::: : .. .:. :.:::.::::. ::::::.:..:::::::::::.: NP_536 PGSDYINANYIKNQLLGPDENA---KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTRE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH ::.:..::: :::. . :: . : : : . .: :: :..: . .:. : .:.:. NP_536 VEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQ 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII . .::::::::.:::::.::......:::. :::..::::::::::::.::::.:.. : NP_536 YLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG ::.:::::. :::::::.::::::::::::.:::.:. ..::: ....: :..: . NP_536 STKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQE 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 HEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR :: :: : NP_536 SEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLK 540 550 560 570 580 590 >>XP_011519290 (OMIM: 176883) PREDICTED: tyrosine-protei (597 aa) initn: 2365 init1: 939 opt: 2205 Z-score: 1804.1 bits: 343.8 E(85289): 9.5e-94 Smith-Waterman score: 2205; 58.6% identity (81.0% similar) in 548 aa overlap (1-547:1-543) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG : :: ::: ...:..::.:: ::: ::::::::..: :::.:::: . ::::.:::.: XP_011 MLSRGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :.::::::::::::.:::.:: ...: :....: .:.:::::::.:::::::.:::.:: XP_011 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG 70 80 90 100 110 120 130 140 150 160 170 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKY .:: :: ::. .:::::: :.:::::::: . :. ... :. .:::. . :. .: XP_011 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRY 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAET ::: : ::::::::::.::. . :. :. . :.:: .::.:::.::.:: ::.: :. XP_011 TVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQES 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE : .: :::::::.::.:: : :..: :::: :::.::::::::::::.::.:. : : XP_011 EDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE : ::::::: : .. .:. :.:::.::::. ::::::.:..:::::::::::.: XP_011 PGSDYINANYIKNQLLGPDENA---KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTRE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH ::.:..::: :::. . :: . : : : . .: :: :..: . .:. : .:.:. XP_011 VEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQ 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII . .::::::::.:::::.::......:::. :::..::::::::::::.::::.:.. : XP_011 YLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG ::.:::::. :::::::.::::::::::::.:::.:. ..::: ....: :..: . XP_011 STKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQE 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 HEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR :: :: : XP_011 SEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLK 540 550 560 570 580 590 >>NP_002822 (OMIM: 176883) tyrosine-protein phosphatase (595 aa) initn: 2368 init1: 939 opt: 2197 Z-score: 1797.6 bits: 342.6 E(85289): 2.2e-93 Smith-Waterman score: 2197; 58.6% identity (81.2% similar) in 544 aa overlap (5-547:3-541) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::: ...:..::.:: ::: ::::::::..: :::.:::: . ::::.:::.: NP_002 MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :.::::::::::::.:::.:: ...: :....: .:.:::::::.:::::::.:::.:: NP_002 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG 60 70 80 90 100 110 130 140 150 160 170 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKY .:: :: ::. .:::::: :.:::::::: . :. ... :. .:::. . :. .: NP_002 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAET ::: : ::::::::::.::. . :. :. . :.:: .::.:::.::.:: ::.: :. NP_002 TVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQES 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE : .: :::::::.::.:: : :..: :::: :::.::::::::::::.::.:. : : NP_002 EDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE : ::::::: : .. .:.: .:::.::::. ::::::.:..:::::::::::.: NP_002 PGSDYINANYIKNQLLGPDENAK---TYIASQGCLEATVNDFWQMAWQENSRVIVMTTRE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH ::.:..::: :::. . :: . : : : . .: :: :..: . .:. : .:.:. NP_002 VEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQ 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII . .::::::::.:::::.::......:::. :::..::::::::::::.::::.:.. : NP_002 YLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG ::.:::::. :::::::.::::::::::::.:::.:. ..::: ....: :..: . NP_002 STKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQE 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 HEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR :: :: : NP_002 SEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLK 540 550 560 570 580 590 >>NP_536859 (OMIM: 176883) tyrosine-protein phosphatase (624 aa) initn: 2368 init1: 939 opt: 2197 Z-score: 1797.4 bits: 342.7 E(85289): 2.2e-93 Smith-Waterman score: 2197; 58.6% identity (81.2% similar) in 544 aa overlap (5-547:3-541) 10 20 30 40 50 60 pF1KB3 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG :::: ...:..::.:: ::: ::::::::..: :::.:::: . ::::.:::.: NP_536 MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK :.::::::::::::.:::.:: ...: :....: .:.:::::::.:::::::.:::.:: NP_536 DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG 60 70 80 90 100 110 130 140 150 160 170 pF1KB3 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKY .:: :: ::. .:::::: :.:::::::: . :. ... :. .:::. . :. .: NP_536 QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 DVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAET ::: : ::::::::::.::. . :. :. . :.:: .::.:::.::.:: ::.: :. NP_536 TVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQES 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 TDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE : .: :::::::.::.:: : :..: :::: :::.::::::::::::.::.:. : : NP_536 EDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE : ::::::: : .. .:.: .:::.::::. ::::::.:..:::::::::::.: NP_536 PGSDYINANYIKNQLLGPDENAK---TYIASQGCLEATVNDFWQMAWQENSRVIVMTTRE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 VERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYH ::.:..::: :::. . :: . : : : . .: :: :..: . .:. : .:.:. NP_536 VEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQ 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 FRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDII . .::::::::.:::::.::......:::. :::..::::::::::::.::::.:.. : NP_536 YLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB3 REKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKG ::.:::::. :::::::.::::::::::::.:::.:. ..::: ....: :..: . NP_536 STKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQE 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB3 HEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR :: :: : NP_536 SEYGNITYPPAMKNAHAKASRTSSKSLESSAGTVAASPVRRGGQRGLPVPGPPVLSPDLH 540 550 560 570 580 590 >>XP_006719057 (OMIM: 176883) PREDICTED: tyrosine-protei (481 aa) initn: 1732 init1: 939 opt: 1639 Z-score: 1345.7 bits: 258.7 E(85289): 3.2e-68 Smith-Waterman score: 1639; 56.5% identity (78.9% similar) in 432 aa overlap (117-547:1-427) 90 100 110 120 130 140 pF1KB3 QLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGD .:: .:: :: ::. .:::::: :.::: XP_006 MSGGQAETLLQAKGEPWTFLVRESLSQPGD 10 20 30 150 160 170 180 190 200 pF1KB3 FVLSVRTGDDKGESNDGKS-KVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVET ::::: . :. ... :. .:::. . :. .: ::: : ::::::::::.::. . :. XP_006 FVLSVLS--DQPKAGPGSPLRVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEA 40 50 60 70 80 210 220 230 240 250 260 pF1KB3 LGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSR :. . :.:: .::.:::.::.:: ::.: :. : .: :::::::.::.:: : :..: XP_006 SGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQR 90 100 110 120 130 140 270 280 290 300 310 320 pF1KB3 KEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKK :::: :::.::::::::::::.::.:. : : : ::::::: : .. .:. : XP_006 LEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENA---K 150 160 170 180 190 200 330 340 350 360 370 380 pF1KB3 SYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRV .:::.::::. ::::::.:..:::::::::::.:::.:..::: :::. . :: . : XP_006 TYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSV 210 220 230 240 250 260 390 400 410 420 430 440 pF1KB3 RNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHK : : . .: :: :..: . .:. : .:.:.. .::::::::.:::::.::...... XP_006 TNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQR 270 280 290 300 310 320 450 460 470 480 490 500 pF1KB3 QESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMV :::. :::..::::::::::::.::::.:.. : ::.:::::. :::::::.:::::: XP_006 QESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMV 330 340 350 360 370 380 510 520 530 540 550 560 pF1KB3 QTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTP ::::::.:::.:. ..::: ....: :..: . :: :: : XP_006 QTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGNITYPPAMKNAHAKASRTSSKH 390 400 410 420 430 440 570 580 590 pF1KB3 TPPCAEMREDSARVYENVGLMQQQKSFR XP_006 KEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK 450 460 470 480 593 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:10:45 2016 done: Thu Nov 3 12:10:47 2016 Total Scan time: 10.720 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]